Market Movers | Winners: XHLD, TLRY, HPP | Losers: SONN, JANX, ABTC

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On Tuesday, December 2, a calm session left the S&P 500 remaining flat, the Dow 30 remaining flat, and the Nasdaq 100 remaining flat nearly unchanged. Yet under the surface, there was more activity in specific names.
 

List of Market Winners

The following table shows the list of 10 stocks that generated the highest returns on the last trading day:
 

# Ticker Company Name 1-D
Returns
YTD
Returns
1 XHLD TEN 1443.9% -97.8%
2 TLRY Tilray Brands 885.4% -42.0%
3 HPP Hudson Pacific Properties 617.7% -33.0%
4 EB Eventbrite 78.6% 31.8%
5 FOXX Foxx Development 34.8% 5.3%
6 MDB MongoDB 22.2% 72.7%
7 LESL Leslies 21.4% -92.0%
8 FBYD Falcons Beyond Global 20.4% 160.2%
9 IPW iPower 18.6% -50.6%
10 AIHS Senmiao Technology 18.5% -86.8%

 
List of Market Losers

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On the other hand, the following table shows the list of 10 stocks that generated the lowest returns:
 

# Ticker Company Name 1-D
Returns
YTD
Returns
1 SONN Sonnet BioTherapeutics -59.4% -13.7%
2 JANX Janux Therapeutics -53.3% -70.4%
3 ABTC American Bitcoin -38.8% -72.8%
4 FLYE Fly-E -32.3% -87.3%
5 PRPH ProPhase Labs -27.0% -81.4%
6 CD Chaince Digital -23.5% -3.5%
7 ARMP Armata Pharmaceuticals -21.6% 187.0%
8 SYM Symbotic -21.5% 182.4%
9 CTOR Citius Oncology -20.7% 13.0%
10 MTVA MetaVia -20.1% -70.4%

 
Why does this matter? Significant stock moves – up or down – deserve your attention. Sharp declines in fundamentally strong names can offer smart buying opportunities. And when momentum aligns with solid fundamentals, riding the trend can be highly rewarding.

Individual stocks can soar or tank, but one thing matters: staying invested. The Trefis High Quality Portfolio helps you do that.

Movers – Last One Week

Analysing over the last one week (5 trading days), broader market witnessed strong advances in the S&P 500 rising 0.94%, the Dow 30 rising 0.77%, and the Nasdaq 100 rising 2.15%. Participation was broad, although not entirely uniform.
 
List of 1-Week Market Winners

The following table shows the list of 10 stocks that generated the highest returns over the last week:
 

# Ticker Company Name 1-W
Returns
YTD
Returns
1 MBRX Moleculin Biotech 1711.0% -84.4%
2 PHGE BiomX 1528.0% -66.1%
3 KTTA Pasithea Therapeutics 180.1% -62.2%
4 FLYE Fly-E 165.9% -87.3%
5 AHMA Ambitions Enterprise Management 96.3% 163.4%
6 EB Eventbrite 80.8% 31.8%
7 KALA Kala Bio 78.3% -84.1%
8 CSTE Caesarstone 74.9% -61.9%
9 SNBR Sleep Number 69.9% -56.3%
10 QTTB Q32 Bio 67.2% -0.9%

 
List of 1-Week Market Losers

Similarly, the following table shows the 10 stocks that were at the bottom in terms of returns:
 

# Ticker Company Name 1-W
Returns
YTD
Returns
1 SONN Sonnet BioTherapeutics -74.0% -13.7%
2 INHD Inno -69.4% -96.9%
3 CLSD Clearside Biomedical -54.4% -97.1%
4 ABTC American Bitcoin -50.1% -72.8%
5 JANX Janux Therapeutics -49.7% -70.4%
6 IVF INVO Fertility -42.2% -99.4%
7 ATON AlphaTON Capital -39.1% -67.7%
8 TWNP Twin Hospitality -37.7% -92.2%
9 CD Chaince Digital -37.1% -3.5%
10 CYPH Cypherpunk Technologies -36.1% -59.3%

 
Movers – Last One Month

On a slightly wider timeline over the last one month, index performance was mixed — the S&P 500 falling 0.33%, the Dow 30 rising 0.29%, and the Nasdaq 100 falling 1.61% offered no clear consensus. Stock-specific factors shaped outcomes throughout the market.
 
List of 1-Month Market Winners

The following table shows the 10 stocks that generated the maximum returns over the last one month:
 

# Ticker Company Name 1-M
Returns
YTD
Returns
1 ADTX Aditxt 4075.1% -100.0%
2 FLYE Fly-E 2018.9% -87.3%
3 IPST Heritage Distilling 958.2% -82.0%
4 TERN Terns Pharmaceuticals 212.2% 365.5%
5 OLMA Olema Pharmaceuticals 202.7% 365.7%
6 PTN Palatin Technologies 195.2% 1668.5%
7 MRSN Mersana Therapeutics 187.3% -23.0%
8 GLTO Galecto 164.2% 315.9%
9 CYPH Cypherpunk Technologies 161.6% -59.3%
10 PACS PACS 160.5% 140.0%

 
List of 1-Month Market Losers

In the same period, these 10 stocks were at the bottom in terms of returns:
 

# Ticker Company Name 1-M
Returns
YTD
Returns
1 CLSD Clearside Biomedical -89.9% -97.1%
2 KRRO Korro Bio -87.1% -86.1%
3 INHD Inno -86.5% -96.9%
4 IVP Inspire Veterinary Partners -84.2% -97.3%
5 CMND Clearmind Medicine -83.7% -90.6%
6 APLT Applied Therapeutics -81.5% -75.1%
7 ECDA ECD Automotive Design -79.7% -98.9%
8 MIGI Mawson Infrastructure -79.5% -72.0%
9 SLRX Salarius Pharmaceuticals -78.0% -96.9%
10 MVO MV Oil Trust -77.9% -85.1%

 

Picking winners on a consistent basis is not an easy task – especially given the volatility associated with a single stock. Instead, the Trefis High Quality (HQ) Portfolio, with a collection of 30 stocks, has a track record of comfortably outperforming its benchmark that includes all 3 — the S&P 500, S&P mid-cap, and Russell 2000 indices. Why is that? As a group, HQ Portfolio stocks provided better returns with less risk versus the benchmark index; less of a roller-coaster ride, as evident in HQ Portfolio performance metrics.