Market Movers | Winners: XWEL, LRMR, CDIO | Losers: NUCL, CASI, KTWO
On Wednesday, February 25, markets rallied broadly, with the S&P 500 rising 0.81%, the Dow 30 rising 0.63%, and the Nasdaq 100 rising 1.41%. While many stocks participated in the rally, some lagged behind.
List of Market Winners
The following table shows the list of 10 stocks that generated the highest returns on the last trading day:
| # | Ticker | Company Name | 1-D Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | XWEL | XWELL | 220.1% | 162.6% |
| 2 | LRMR | Larimar Therapeutics | 61.2% | 56.2% |
| 3 | CDIO | Cardio Diagnostics | 60.4% | 95.9% |
| 4 | RYAM | Rayonier Advanced Materials | 42.7% | 73.7% |
| 5 | YOU | Clear Secure | 39.0% | 32.6% |
| 6 | NITO | N2OFF | 38.6% | -27.4% |
| 7 | RCKY | Rocky Brands | 37.4% | 56.8% |
| 8 | UPXI | Upexi | 36.0% | -50.8% |
| 9 | CRCL | Circle Internet | 35.5% | 4.8% |
| 10 | SGML | Sigma Lithium | 29.9% | 24.1% |
List of Market Losers
On the other hand, the following table shows the list of 10 stocks that generated the lowest returns:
| # | Ticker | Company Name | 1-D Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | NUCL | Eagle Nuclear Energy | -76.1% | -76.1% |
| 2 | CASI | CASI Pharmaceuticals | -74.1% | -75.6% |
| 3 | KTWO | K2 Capital Acquisition | -64.1% | -64.1% |
| 4 | IXHL | Incannex Healthcare | -42.1% | -55.7% |
| 5 | MNKD | MannKind | -36.8% | -38.3% |
| 6 | MGN | Megan | -31.7% | -20.1% |
| 7 | DRVN | Driven Brands | -30.2% | -21.7% |
| 8 | AIDX | 20/20 Biolabs | -28.8% | -76.2% |
| 9 | ASPN | Aspen Aerogels | -27.8% | -9.2% |
| 10 | TLF | Tandy Leather Factory | -23.5% | 48.5% |
Why does this matter? Significant stock moves – up or down – deserve your attention. Sharp declines in fundamentally strong names can offer smart buying opportunities. And when momentum aligns with solid fundamentals, riding the trend can be highly rewarding. Among the stocks above, we find Clear Secure (YOU) attractive
Individual stocks can be volatile, but markets aren’t spared either. Think 2008 and 2020. Volatility happens. See how Trefis’ Boston-based wealth management partner’s asset allocation framework handled both.
Movers – Last One Week
Analysing over the last one week (5 trading days), index performance was mixed — the S&P 500 rising 0.94%, the Dow 30 falling 0.36%, and the Nasdaq 100 rising 1.73% offered no clear consensus. Stock-specific factors shaped outcomes throughout the market.
List of 1-Week Market Winners
The following table shows the list of 10 stocks that generated the highest returns over the last week:
| # | Ticker | Company Name | 1-W Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | ADVB | Advanced Biomed | 1748.9% | -32.5% |
| 2 | BTM | Bitcoin Depot | 430.1% | -44.1% |
| 3 | TRNR | Interactive Strength | 406.2% | -75.8% |
| 4 | NBY | NovaBay Pharmaceuticals | 257.0% | -94.5% |
| 5 | XWEL | XWELL | 202.5% | 162.6% |
| 6 | CDIO | Cardio Diagnostics | 149.3% | 95.9% |
| 7 | LRMR | Larimar Therapeutics | 101.7% | 56.2% |
| 8 | KLTO | Klotho Neurosciences | 80.6% | 47.4% |
| 9 | AXTI | AXT | 74.0% | 150.6% |
| 10 | EZRA | Reliance Global | 66.2% | 13.6% |
List of 1-Week Market Losers
Similarly, the following table shows the 10 stocks that were at the bottom in terms of returns:
| # | Ticker | Company Name | 1-W Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | ROC | Rank One Computing | -91.9% | -91.9% |
| 2 | GOSS | Gossamer Bio | -82.5% | -87.7% |
| 3 | NUCL | Eagle Nuclear Energy | -76.1% | -76.1% |
| 4 | CASI | CASI Pharmaceuticals | -73.4% | -75.6% |
| 5 | KTWO | K2 Capital Acquisition | -64.1% | -64.1% |
| 6 | VEEE | Twin Vee PowerCats | -55.8% | -75.0% |
| 7 | GRAL | GRAIL | -49.4% | -39.5% |
| 8 | UHG | United Homes | -48.2% | -26.3% |
| 9 | MBRX | Moleculin Biotech | -46.4% | -22.1% |
| 10 | WSHP | WeShop | -45.8% | -78.4% |
Movers – Last One Month
On a slightly wider timeline over the last one month, index performance was mixed — the S&P 500 falling 0.06%, the Dow 30 rising 0.14%, and the Nasdaq 100 falling 1.49% offered no clear consensus. Stock-specific factors shaped outcomes throughout the market.
List of 1-Month Market Winners
The following table shows the 10 stocks that generated the maximum returns over the last one month:
| # | Ticker | Company Name | 1-M Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | SCPQ | Social Commerce Partners | 9909900.0% | 9909900.0% |
| 2 | RPC | Ridgepost Capital | 4144900.0% | 4144900.0% |
| 3 | LIFE | Ethos Technologies | 1335.8% | 1335.8% |
| 4 | ATOS | Atossa Therapeutics | 523.1% | -51.8% |
| 5 | PBM | Psyence Biomedical | 286.2% | -91.3% |
| 6 | XWEL | XWELL | 260.9% | 162.6% |
| 7 | SNSE | Sensei Biotherapeutics | 236.6% | 220.8% |
| 8 | CDIO | Cardio Diagnostics | 193.4% | 95.9% |
| 9 | SGN | Signing Day Sports | 183.0% | -32.0% |
| 10 | REVB | Revelation Biosciences | 156.3% | -55.9% |
List of 1-Month Market Losers
In the same period, these 10 stocks were at the bottom in terms of returns:
| # | Ticker | Company Name | 1-M Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | RPGL | Republic Power | -96.0% | -97.5% |
| 2 | QNCX | Quince Therapeutics | -95.6% | -96.1% |
| 3 | ROC | Rank One Computing | -91.9% | -91.9% |
| 4 | NBY | NovaBay Pharmaceuticals | -90.2% | -94.5% |
| 5 | CALC | CalciMedica | -89.6% | -91.8% |
| 6 | GOSS | Gossamer Bio | -85.7% | -87.7% |
| 7 | PFSA | Profusa | -82.8% | -84.0% |
| 8 | BRTX | BioRestorative Therapies | -79.9% | -80.8% |
| 9 | CASI | CASI Pharmaceuticals | -78.8% | -75.6% |
| 10 | GUTS | Fractyl Health | -76.8% | -77.0% |
Picking winners on a consistent basis is not an easy task – especially given the volatility associated with a single stock. Instead, the Trefis High Quality (HQ) Portfolio, with a collection of 30 stocks, has a track record of comfortably outperforming its benchmark that includes all 3 — the S&P 500, S&P mid-cap, and Russell 2000 indices. Why is that? As a group, HQ Portfolio stocks provided better returns with less risk versus the benchmark index; less of a roller-coaster ride, as evident in HQ Portfolio performance metrics.