Tearsheet

Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.

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Valuation becoming less expensive
P/S 6M Chg %Price/Sales change over 6 months. Declining P/S indicates valuation has become less expensive. is -40%

Megatrend and thematic drivers
Megatrends include Aging Population & Chronic Disease, and Precision Medicine. Themes include Diabetes Management, Targeted Therapies, Show more.

Weak multi-year price returns
2Y Excs Rtn is -64%, 3Y Excs Rtn is -91%

Expensive valuation multiples
P/EBITPrice/EBIT or Price/(Operating Income) ratio is 99x, P/CFOPrice/(Cash Flow from Operations). CFO is cash before capital expenditures. is 56x

Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -6.5%

Key risks
MNKD key risks include [1] the potential failure of its clinical development programs, Show more.

0 Valuation becoming less expensive
P/S 6M Chg %Price/Sales change over 6 months. Declining P/S indicates valuation has become less expensive. is -40%
1 Megatrend and thematic drivers
Megatrends include Aging Population & Chronic Disease, and Precision Medicine. Themes include Diabetes Management, Targeted Therapies, Show more.
2 Weak multi-year price returns
2Y Excs Rtn is -64%, 3Y Excs Rtn is -91%
3 Expensive valuation multiples
P/EBITPrice/EBIT or Price/(Operating Income) ratio is 99x, P/CFOPrice/(Cash Flow from Operations). CFO is cash before capital expenditures. is 56x
4 Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -6.5%
5 Key risks
MNKD key risks include [1] the potential failure of its clinical development programs, Show more.

Valuation, Metrics & Events

Price Chart

Why The Stock Moved

Qualitative Assessment

AI Analysis | Feedback

MannKind (MNKD) stock has lost about 40% since 1/31/2026 because of the following key factors:

1. Direct Threat to Key Royalty Revenue from United Therapeutics' Tresmi.

MannKind's stock experienced a significant drop of 36.82% on February 25, 2026, following the announcement by its collaboration partner, United Therapeutics, of a new proprietary soft mist inhaler called Tresmi. This product directly competes with Tyvaso DPI, for which MannKind receives a 9% royalty on net sales, posing a substantial threat to a key revenue stream.

2. Increased Operating Expenses and Q1 Net Loss.

For the first quarter of 2026 (ending March 31, 2026), MannKind reported a GAAP net loss of $16.6 million, or $0.05 per share, which missed analyst estimates of -$0.02 per share. This loss was largely attributed to increased operating expenses, including a 56% rise in research and development expenses to $17.2 million and a 116% surge in selling, general, and administrative expenses to $54.1 million, reflecting substantial investments in pipeline development and commercialization.

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Stock Movement Drivers

Fundamental Drivers

The -39.1% change in MNKD stock from 1/31/2026 to 5/10/2026 was primarily driven by a -46.8% change in the company's P/S Multiple.
(LTM values as of)13120265102026Change
Stock Price ($)5.783.52-39.1%
Change Contribution By: 
Total Revenues ($ Mil)31436115.0%
P/S Multiple5.73.0-46.8%
Shares Outstanding (Mil)307308-0.5%
Cumulative Contribution-39.1%

LTM = Last Twelve Months as of date shown

Market Drivers

1/31/2026 to 5/10/2026
ReturnCorrelation
MNKD-39.1% 
Market (SPY)3.6%17.0%
Sector (XLV)-6.9%21.2%

Fundamental Drivers

The -37.0% change in MNKD stock from 10/31/2025 to 5/10/2026 was primarily driven by a -46.8% change in the company's P/S Multiple.
(LTM values as of)103120255102026Change
Stock Price ($)5.593.52-37.0%
Change Contribution By: 
Total Revenues ($ Mil)30236119.6%
P/S Multiple5.63.0-46.8%
Shares Outstanding (Mil)305308-1.1%
Cumulative Contribution-37.0%

LTM = Last Twelve Months as of date shown

Market Drivers

10/31/2025 to 5/10/2026
ReturnCorrelation
MNKD-37.0% 
Market (SPY)5.5%13.9%
Sector (XLV)0.3%19.0%

Fundamental Drivers

The -30.2% change in MNKD stock from 4/30/2025 to 5/10/2026 was primarily driven by a -39.0% change in the company's P/S Multiple.
(LTM values as of)43020255102026Change
Stock Price ($)5.043.52-30.2%
Change Contribution By: 
Total Revenues ($ Mil)28636126.4%
P/S Multiple4.93.0-39.0%
Shares Outstanding (Mil)279308-9.4%
Cumulative Contribution-30.2%

LTM = Last Twelve Months as of date shown

Market Drivers

4/30/2025 to 5/10/2026
ReturnCorrelation
MNKD-30.2% 
Market (SPY)30.4%16.6%
Sector (XLV)4.0%23.9%

Fundamental Drivers

The -8.6% change in MNKD stock from 4/30/2023 to 5/10/2026 was primarily driven by a -70.4% change in the company's P/S Multiple.
(LTM values as of)43020235102026Change
Stock Price ($)3.853.52-8.6%
Change Contribution By: 
Total Revenues ($ Mil)100361261.6%
P/S Multiple10.23.0-70.4%
Shares Outstanding (Mil)263308-14.5%
Cumulative Contribution-8.6%

LTM = Last Twelve Months as of date shown

Market Drivers

4/30/2023 to 5/10/2026
ReturnCorrelation
MNKD-8.6% 
Market (SPY)78.7%21.1%
Sector (XLV)13.0%26.5%

Return vs. Risk

Price Returns Compared

 202120222023202420252026Total [1]
Returns
MNKD Return40%21%-31%77%-12%-37%13%
Peers Return9%-9%4%-11%10%6%7%
S&P 500 Return27%-19%24%23%16%7%95%

Monthly Win Rates [3]
MNKD Win Rate50%50%50%67%50%60% 
Peers Win Rate52%50%55%43%50%60% 
S&P 500 Win Rate75%42%67%75%67%60% 

Max Drawdowns [4]
MNKD Max Drawdown0%-40%-37%-11%-47%-60% 
Peers Max Drawdown-11%-23%-19%-26%-19%-14% 
S&P 500 Max Drawdown-1%-25%-1%-2%-15%-7% 


[1] Cumulative total returns since the beginning of 2021
[2] Peers: ACT, ALKS, LIVN, PRGO, PCRX. See MNKD Returns vs. Peers.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 5/8/2026 (YTD)

How Low Can It Go

EventMNKDS&P 500
2025 US Tariff Shock
  % Loss-32.7%-18.8%
  % Gain to Breakeven48.5%23.1%
  Time to Breakeven81 days79 days
Summer-Fall 2023 Five Percent Yield Shock
  % Loss-23.1%-9.5%
  % Gain to Breakeven30.0%10.5%
  Time to Breakeven112 days24 days
2023 SVB Regional Banking Crisis
  % Loss-29.8%-6.7%
  % Gain to Breakeven42.5%7.1%
  Time to Breakeven98 days31 days
2022 Inflation Shock & Fed Tightening
  % Loss-41.1%-24.5%
  % Gain to Breakeven69.8%32.4%
  Time to Breakeven87 days427 days
2020 COVID-19 Crash
  % Loss-41.2%-33.7%
  % Gain to Breakeven69.9%50.9%
  Time to Breakeven67 days140 days
Q4 2018 Fed Policy Error / Growth Scare
  % Loss-43.3%-19.2%
  % Gain to Breakeven76.5%23.7%
  Time to Breakeven62 days105 days

Compare to ACT, ALKS, LIVN, PRGO, PCRX

In The Past

MannKind's stock fell -32.7% during the 2025 US Tariff Shock. Such a loss loss requires a 48.5% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

EventMNKDS&P 500
2025 US Tariff Shock
  % Loss-32.7%-18.8%
  % Gain to Breakeven48.5%23.1%
  Time to Breakeven81 days79 days
Summer-Fall 2023 Five Percent Yield Shock
  % Loss-23.1%-9.5%
  % Gain to Breakeven30.0%10.5%
  Time to Breakeven112 days24 days
2023 SVB Regional Banking Crisis
  % Loss-29.8%-6.7%
  % Gain to Breakeven42.5%7.1%
  Time to Breakeven98 days31 days
2022 Inflation Shock & Fed Tightening
  % Loss-41.1%-24.5%
  % Gain to Breakeven69.8%32.4%
  Time to Breakeven87 days427 days
2020 COVID-19 Crash
  % Loss-41.2%-33.7%
  % Gain to Breakeven69.9%50.9%
  Time to Breakeven67 days140 days
Q4 2018 Fed Policy Error / Growth Scare
  % Loss-43.3%-19.2%
  % Gain to Breakeven76.5%23.7%
  Time to Breakeven62 days105 days
2016-2017 Trump Reflation Bond Selloff
  % Loss-76.8%-3.7%
  % Gain to Breakeven331.8%3.9%
  Time to Breakeven154 days6 days
2011 US Debt Ceiling Crisis & European Contagion
  % Loss-36.6%-17.9%
  % Gain to Breakeven57.8%21.8%
  Time to Breakeven44 days123 days
2010 Eurozone Sovereign Debt Crisis / Flash Crash
  % Loss-29.3%-15.4%
  % Gain to Breakeven41.5%18.2%
  Time to Breakeven36 days125 days
2008-2009 Global Financial Crisis
  % Loss-75.8%-53.4%
  % Gain to Breakeven313.4%114.4%
  Time to Breakeven105 days1085 days

Compare to ACT, ALKS, LIVN, PRGO, PCRX

In The Past

MannKind's stock fell -32.7% during the 2025 US Tariff Shock. Such a loss loss requires a 48.5% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

About MannKind (MNKD)

MannKind Corporation, a biopharmaceutical company, focuses on the development and commercialization of inhaled therapeutic products for endocrine and orphan lung diseases in the United States. It offers Afrezza, an inhaled insulin used to improve glycemic control in adults with diabetes. It also promotes Thyquidity to adult and pediatric endocrinologists, and other healthcare providers for the treatment of hypothyroidism. The company has a license and collaboration agreement with United Therapeutics Corporation. It also has an agreement with NRx Pharmaceuticals to develop a dry powder formulation of ZYESAMI (aviptadil), a synthetic form of human vasoactive intestinal peptide to help protect cells against inflammatory conditions. MannKind Corporation was incorporated in 1991 and is headquartered in Westlake Village, California.

AI Analysis | Feedback

  • The Eli Lilly of inhaled insulin.
  • The Dyson of inhaled drug delivery.
  • Like a specialized Vertex Pharmaceuticals, but focused on inhaled treatments for endocrine and orphan lung diseases.

AI Analysis | Feedback

  • Afrezza: An inhaled insulin used to improve glycemic control in adults with diabetes.
  • Thyquidity: A product promoted for the treatment of hypothyroidism.
  • ZYESAMI (aviptadil): A dry powder formulation under development in collaboration with NRx Pharmaceuticals to help protect cells against inflammatory conditions.

AI Analysis | Feedback

MannKind Corporation (MNKD) sells its products primarily to other companies within the healthcare supply chain and through strategic collaborations. Its major customers include:

  • Pharmaceutical Wholesalers: These companies are the primary direct purchasers of MannKind’s commercial products, such as Afrezza and Thyquidity, for distribution to pharmacies, hospitals, and other healthcare providers. The largest pharmaceutical wholesalers in the United States, which typically serve as major customers for biopharmaceutical companies, include:
    • McKesson Corporation (MCK)
    • Cardinal Health, Inc. (CAH)
    • AmerisourceBergen Corporation (ABC)
  • United Therapeutics Corporation (UTHR): As per the company description, MannKind has a license and collaboration agreement with United Therapeutics Corporation. This agreement indicates that United Therapeutics is a significant partner and customer for licensed products or services related to their collaboration.
  • NRx Pharmaceuticals (NRXP): MannKind has an agreement with NRx Pharmaceuticals to develop a dry powder formulation of ZYESAMI. This type of development agreement often involves payments for services or future product supply, making NRx Pharmaceuticals a customer in this context.

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  • United Therapeutics Corporation (UTHR)
  • Bachem AG (BANB)
  • Dr. Reddy's Laboratories Ltd. (RDY)
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Michael Castagna, Chief Executive Officer

Michael Castagna became CEO of MannKind Corporation and joined its board of directors in 2017, bringing over 25 years of experience in healthcare, pharmaceuticals, and biotechnology to the company's product and medical device development strategy. Prior to MannKind, he served as Vice President at Amgen, where he guided both the Lifecycle Management and Global Commercial Biosimilar business areas. He spent a combined 10 years at Bristol-Myers Squibb, focusing on medical, marketing, and sales, and also directed their Immunoscience division. His other industry experience includes serving as a Vice President at Sandoz (Novartis), where he established the U.S. Biologics Business Unit, and as a Director at Merck, Serono, Pharmasset, and DuPont Pharmaceuticals.

Christopher Prentiss, Chief Financial Officer

Christopher Prentiss was appointed Chief Financial Officer of MannKind Corporation effective April 22, 2024. He brings over two decades of financial leadership experience within the biopharma sector. Prior to joining MannKind, Mr. Prentiss served as CFO of ADARx Pharmaceuticals, where he helped facilitate a funding round of nearly $250 million. His professional history also includes a tenure as CFO at Adamas Pharmaceuticals, where he contributed to significant company milestones such as product launches and revenue growth.

Dominic Marasco, President, Endocrine Business Unit

Dominic Marasco joined MannKind Corporation as President, Endocrine Business Unit, effective January 6, 2025. He has over 25 years of experience in driving commercial success within the biopharma and biotech sectors. Mr. Marasco previously held the position of Executive President, Chief Commercial Officer for Envision Pharma Group, and prior to that, he was Chief Commercial Officer at BioAgilytix Labs, Inc. His background also includes leadership roles at Syneos Health, Amgen, and Sandoz Biopharmaceuticals.

Ajay Ahuja, Executive Vice President and Chief Medical Officer

Dr. Ajay Ahuja joined MannKind Corporation as Executive Vice President and Chief Medical Officer in 2025, with his appointment effective September 29, 2025. A pediatrician and cardiologist, Dr. Ahuja is a seasoned biopharmaceutical leader with over two decades of industry experience. His expertise spans medical devices, drug delivery platforms, and biopharmaceuticals, particularly in therapeutic areas such as diabetes, cardiovascular disease, respiratory medicine, and infectious diseases. Before MannKind, Dr. Ahuja held leadership roles in clinical development, medical affairs, and commercial strategy at companies including Kardigan Bio, Takeda, Pfizer, GSK, and Novartis.

Sanjay Singh, Executive Vice President, Technical Operations

Sanjay Singh is MannKind's Executive Vice President of Technical Operations, leading the company's Danbury facility and overseeing commercial and contract manufacturing. He brings over 30 years of experience in pharmaceutical technical operations, having worked with multiple technologies, delivery systems, and therapeutic areas. Prior to joining MannKind in 2022, Mr. Singh was Associate President of Operations for Aurobindo Pharma USA and served as Senior VP of Operations for Aurobindo Pharma India.

AI Analysis | Feedback

The key risks to MannKind Corporation (MNKD) include the following, listed in order from most significant to least significant:

  1. Dependence on United Therapeutics and Competition from New Products: MannKind is heavily reliant on its collaboration with United Therapeutics, particularly for royalties derived from Tyvaso DPI. A significant and immediate risk is United Therapeutics' recent unveiling of Tresmi, a soft-mist treprostinil inhaler, which has been described as a "category killer product" and could potentially compete with or replace Tyvaso DPI. This development introduces uncertainty regarding the long-term durability of MannKind's Tyvaso DPI royalties, a key revenue stream.
  2. Regulatory and Market Adoption Challenges for Products: As a biopharmaceutical company, MannKind faces ongoing regulatory risks. Immediate risks include upcoming FDA decisions on the Afrezza pediatric sBLA in May 2026 and the Furoscix ReadyFlow Autoinjector sNDA in July 2026. Delays or negative outcomes in these regulatory processes could materially impact near-term growth expectations. Historically, Afrezza has also encountered significant market adoption hurdles, including issues with insurance coverage and the requirement for lung function tests, which could recur with new product introductions or expanded indications.
  3. Need for Additional Capital and Financial Health: MannKind has a history of requiring additional capital to fund its operations, research and development activities, and commercialization efforts. Despite recent initiatives like a sale-leaseback transaction to generate capital, indicators such as a low Altman Z-Score suggest an elevated financial distress risk and highlight that interest payments are not consistently well covered by earnings. The company must continuously manage its financial health and access to capital to support its growth strategy and ongoing operations.

AI Analysis | Feedback

null

AI Analysis | Feedback

MannKind Corporation's primary products, Afrezza and Thyquidity, operate within addressable markets of significant size. Information regarding the addressable market for their collaboration product, ZYESAMI, is not available. * **Afrezza (Inhaled Insulin)** The global inhalable insulin market was valued at USD 630 million in 2024 and is projected to reach USD 1,476.10 million by 2032. Within North America, the inhaled insulin market was valued at USD 237.51 million in 2024 and is expected to reach approximately USD 1,012.83 million by 2034. The U.S. inhalable insulin market held the largest revenue share of 77.9% within North America in 2024. The broader global non-injectable insulin market, which includes inhalable insulin, is estimated at USD 1.7 billion in 2024 and is projected to reach USD 6.1 billion by 2034. * **Thyquidity (Hypothyroidism Treatment)** The global thyroid gland disorder treatment market was valued at USD 2.22 billion in 2023 and is projected to grow at a Compound Annual Growth Rate (CAGR) of 3.6% from 2024 to 2030. Hypothyroidism was the dominant segment within this market, accounting for a 68.7% share in 2023. North America led the global thyroid gland disorder treatment market with a revenue share of over 35.44% in 2023, with the U.S. market alone accounting for 29.4% of the global market in the same year. Additionally, the 7 major hypothyroidism markets (United States, EU4, UK, and Japan) collectively reached USD 1.6 billion in 2024 and are anticipated to grow to USD 2.3 billion by 2035. The global hypothyroidism market is projected to reach USD 1,817.13 million (approximately USD 1.82 billion) by 2030. * **ZYESAMI (aviptadil)** null

AI Analysis | Feedback

MannKind (MNKD) is expected to drive future revenue growth over the next 2-3 years through several key areas:

  1. Continued Growth in Tyvaso DPI Royalties and Collaboration Revenue: MannKind's collaboration with United Therapeutics for Tyvaso DPI, an inhaled therapy for pulmonary arterial hypertension and pulmonary hypertension associated with interstitial lung disease, continues to be a significant revenue driver. The company receives royalties on net sales of Tyvaso DPI and revenue from its manufacturing activities. Strong patient demand for this product has consistently driven increased revenue, with MannKind anticipating receiving between $700 million and $1 billion in cash from Tyvaso over the next few years.
  2. Expansion and Demand for Afrezza: Afrezza, MannKind's inhaled insulin product, is expected to see continued revenue growth driven by increasing patient demand, favorable pricing strategies, and improved gross-to-net adjustments. A significant anticipated catalyst is the potential FDA approval for a pediatric indication, with a decision expected by May 29th, 2026. Additionally, an FDA label update to simplify switching from injected insulin is expected to further support its adoption. International expansion efforts are also contributing to Afrezza's growth.
  3. Growth of FUROSCIX with Autoinjector Launch: Following the acquisition of scPharmaceuticals, FUROSCIX has become a key growth engine within MannKind's cardiometabolic franchise. The anticipated approval of the FUROSCIX ReadyFlow Autoinjector, with a PDUFA date of July 26th, 2026, is considered a major catalyst. This autoinjector is expected to significantly expand market reach, particularly within hospitals, and accelerate sales growth, with MannKind aiming for FUROSCIX revenues in the range of $110 million to $120 million in 2026.
  4. Advancement of Orphan Lung Disease Pipeline (MNKD-101 and MNKD-201): MannKind is actively advancing its pipeline products for orphan lung diseases. MNKD-101 (clofazimine inhalation suspension for NTM lung disease) is progressing into a global Phase 3 clinical trial. Furthermore, MNKD-201 (nintedanib DPI for Idiopathic Pulmonary Fibrosis - IPF) has successfully completed Phase 1 studies and is on track for further clinical development, including Phase 2/3 trials. Successful development and potential commercialization of these pipeline assets represent future revenue opportunities.

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Share Issuance

  • MannKind reached agreements in December 2024 to exchange approximately $193.7 million of its convertible senior notes for 26,749,559 shares of common stock and about $89.2 million in cash.
  • The number of shares issued and outstanding increased from 302,959,782 as of December 31, 2024, to 307,832,587 as of December 31, 2025.
  • Shares outstanding (diluted average) grew by 10.39% to $313.3 million in 2025 from $283.8 million in 2024, and by 6.3% in 2024 from $267.0 million in 2023.

Inbound Investments

  • MannKind receives royalties from United Therapeutics for the sales of Tyvaso DPI, leveraging MannKind's Technosphere drug delivery technology.
  • The company anticipates receiving $700 million to $1 billion in cash from Tyvaso over the next few years.
  • A minimum supply agreement with United Therapeutics is expected to provide approximately $100 million in revenue for 2025 and 2026, and about $50 million annually thereafter, ensuring a predictable cash flow.

Outbound Investments

  • MannKind successfully completed the acquisition of scPharmaceuticals Inc. in October 2025.
  • This acquisition is projected to diversify and accelerate MannKind's double-digit revenue growth, primarily driven by FUROSCIX.

Capital Expenditures

  • Capital expenditures for MannKind were $4.57 million in 2025, $9.69 million in 2024, and $42 million in 2023.
  • In Q4 2025, capital expenditures amounted to $2.0 million.
  • Capital expenditures absorb a significant portion of operating cash flow, contributing to a low free cash flow margin of 3.9%.

Better Bets vs. MannKind (MNKD)

Trade Ideas

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Recent Active Movers

Peer Comparisons

Peers to compare with:

Financials

MNKDACTALKSLIVNPRGOPCRXMedian
NameMannKind Enact Alkermes LivaNova Perrigo Pacira B. 
Mkt Price3.5244.0434.9971.8611.7123.1529.07
Mkt Cap1.16.25.83.91.60.92.8
Rev LTM3611,2411,5621,4334,1787351,337
Op Inc LTM19-19219226716192
FCF LTM13722222161108133147
FCF 3Y Avg13716366112190155173
CFO LTM19722256246189142217
CFO 3Y Avg29716406169291168230

Growth & Margins

MNKDACTALKSLIVNPRGOPCRXMedian
NameMannKind Enact Alkermes LivaNova Perrigo Pacira B. 
Rev Chg LTM21.2%2.0%3.2%12.4%-3.6%4.6%3.9%
Rev Chg 3Y Avg42.9%3.9%15.0%11.1%-2.8%3.2%7.5%
Rev Chg Q15.1%1.7%28.2%14.3%-7.2%5.0%9.7%
QoQ Delta Rev Chg LTM3.4%0.4%5.9%3.3%-1.8%1.2%2.2%
Op Inc Chg LTM-76.0%--50.9%19.1%-33.6%-80.7%-50.9%
Op Inc Chg 3Y Avg79.2%-1,583.6%106.7%32.6%15.0%79.2%
Op Mgn LTM5.2%-12.3%13.4%6.4%2.2%6.4%
Op Mgn 3Y Avg15.1%-21.8%9.8%6.8%9.2%9.8%
QoQ Delta Op Mgn LTM-8.1%--4.9%-1.0%-1.0%-0.5%-1.0%
CFO/Rev LTM5.3%58.2%16.4%17.1%4.5%19.4%16.8%
CFO/Rev 3Y Avg11.0%59.3%25.4%12.7%6.6%23.8%18.2%
FCF/Rev LTM3.6%58.2%14.2%11.2%2.6%18.1%12.7%
FCF/Rev 3Y Avg4.1%59.3%22.9%8.4%4.3%22.0%15.2%

Valuation

MNKDACTALKSLIVNPRGOPCRXMedian
NameMannKind Enact Alkermes LivaNova Perrigo Pacira B. 
Mkt Cap1.16.25.83.91.60.92.8
P/S3.05.03.72.70.41.32.9
P/Op Inc57.8-30.320.46.158.630.3
P/EBIT98.76.824.523.9-1.034.424.2
P/E-45.49.238.136.7-0.9182.322.9
P/CFO56.38.622.716.08.66.612.3
Total Yield-2.2%12.8%2.6%2.7%-109.5%0.5%1.6%
Dividend Yield0.0%2.0%0.0%0.0%2.5%0.0%0.0%
FCF Yield 3Y Avg1.1%13.5%7.1%4.1%6.1%13.7%6.6%
D/E0.30.10.30.12.20.40.3
Net D/E0.2-0.30.2-0.02.00.20.2

Returns

MNKDACTALKSLIVNPRGOPCRXMedian
NameMannKind Enact Alkermes LivaNova Perrigo Pacira B. 
1M Rtn37.0%5.0%4.9%14.5%7.8%-2.7%6.4%
3M Rtn-39.1%2.5%0.2%8.0%-18.2%10.2%1.4%
6M Rtn-37.5%20.3%6.4%42.4%-15.3%5.0%5.7%
12M Rtn-22.8%24.6%16.1%63.1%-53.6%-7.8%4.1%
3Y Rtn-17.0%103.8%20.7%52.9%-62.0%-44.9%1.9%
1M Excs Rtn29.1%-5.3%-8.2%5.0%2.1%-11.2%-1.6%
3M Excs Rtn-45.8%-4.2%-6.5%1.2%-25.0%3.5%-5.4%
6M Excs Rtn-50.8%15.0%3.7%32.6%-27.8%-2.9%0.4%
12M Excs Rtn-58.8%-8.2%-16.2%33.8%-84.0%-39.5%-27.8%
3Y Excs Rtn-91.3%23.5%-49.5%-29.6%-144.9%-127.2%-70.4%

Comparison Analyses

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FDA Approved Drugs Data

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Post-Approval Fwd Returns
FDA
App #
Brand
Name
Generic
Name
Dosage
Form
FDA
Approval
3M
Rtn
6M
Rtn
1Y
Rtn
2Y
Rtn
Total
Rtn
BLA022472  AFREZZAinsulin recombinant humanpowder6272014-39.0%-43.4%-41.8%-87.5%-93.0%

Financials

Segment Financials

Revenue by Segment
$ Mil20252024202320222021
Single Segment28619910075 
Product revenue    32
Services    33
Total2861991007565


Net Income by Segment
$ Mil20252024202320222021
Single Segment28-12   
Total28-12   


Price Behavior

Price Behavior
Market Price$3.52 
Market Cap ($ Bil)1.1 
First Trading Date07/28/2004 
Distance from 52W High-43.3% 
   50 Days200 Days
DMA Price$2.73$4.60
DMA Trenddowndown
Distance from DMA29.0%-23.5%
 3M1YR
Volatility102.3%72.1%
Downside Capture0.320.35
Upside Capture-176.5716.43
Correlation (SPY)12.8%15.0%
MNKD Betas & Captures as of 4/30/2026

 1M2M3M6M1Y3Y
Beta1.471.481.010.720.890.76
Up Beta1.442.011.891.391.280.56
Down Beta15.331.491.450.530.850.79
Up Capture120%46%-95%-39%11%40%
Bmk +ve Days15223166141428
Stock +ve Days14192955114350
Down Capture430%207%196%130%119%102%
Bmk -ve Days4183056108321
Stock -ve Days8223361126371

[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with MNKD
MNKD-25.9%72.1%-0.09-
Sector ETF (XLV)7.9%15.4%0.3023.1%
Equity (SPY)29.0%12.5%1.8316.1%
Gold (GLD)39.8%27.0%1.2215.7%
Commodities (DBC)50.6%18.0%2.21-6.0%
Real Estate (VNQ)13.0%13.5%0.6615.5%
Bitcoin (BTCUSD)-17.4%42.1%-0.344.7%

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Based On 5-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with MNKD
MNKD-4.0%59.6%0.17-
Sector ETF (XLV)4.9%14.6%0.1631.2%
Equity (SPY)12.8%17.1%0.5931.5%
Gold (GLD)20.9%17.9%0.9510.6%
Commodities (DBC)13.8%19.1%0.594.7%
Real Estate (VNQ)3.4%18.8%0.0829.4%
Bitcoin (BTCUSD)7.0%56.0%0.3413.7%

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Based On 10-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with MNKD
MNKD-6.1%83.6%0.29-
Sector ETF (XLV)9.3%16.5%0.4621.8%
Equity (SPY)15.1%17.9%0.7222.8%
Gold (GLD)13.4%15.9%0.695.6%
Commodities (DBC)9.3%17.8%0.448.0%
Real Estate (VNQ)5.8%20.7%0.2418.2%
Bitcoin (BTCUSD)67.8%66.9%1.079.3%

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Short Interest

Short Interest: As Of Date4152026
Short Interest: Shares Quantity29.6 Mil
Short Interest: % Change Since 33120260.4%
Average Daily Volume3.4 Mil
Days-to-Cover Short Interest8.8 days
Basic Shares Quantity308.3 Mil
Short % of Basic Shares9.6%

Earnings Returns History

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 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
2/26/2026-7.4%-15.7%-34.3%
11/5/202510.6%-4.2%3.6%
8/6/2025-13.2%-8.3%33.8%
5/8/2025-4.5%-5.8%-9.7%
2/26/2025-4.4%-5.9%-6.8%
11/7/2024-0.6%-5.0%-9.9%
8/7/2024-4.9%-3.8%14.4%
5/8/2024-2.0%1.1%6.1%
...
SUMMARY STATS   
# Positive111013
# Negative131411
Median Positive4.9%11.1%17.8%
Median Negative-4.5%-6.9%-9.9%
Max Positive18.5%35.3%42.5%
Max Negative-13.2%-39.5%-37.5%

SEC Filings

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Report DateFiling DateFiling
03/31/202605/06/202610-Q
12/31/202502/26/202610-K
09/30/202511/05/202510-Q
06/30/202508/06/202510-Q
03/31/202505/08/202510-Q
12/31/202402/26/202510-K
09/30/202411/07/202410-Q
06/30/202408/07/202410-Q
03/31/202405/08/202410-Q
12/31/202302/27/202410-K
09/30/202311/07/202310-Q
06/30/202308/07/202310-Q
03/31/202305/09/202310-Q
12/31/202202/23/202310-K
09/30/202211/08/202210-Q
06/30/202208/09/202210-Q

Recent Forward Guidance [BETA]

Latest: Q1 2026 Earnings Reported 5/6/2026

Forward GuidanceGuidance Change
MetricLowMidHigh% Chg% DeltaChangePrior
2026 Development Milestone Payments 35.00 Mil    
2026 Royalties 0.1    

Prior: Q4 2025 Earnings Reported 2/26/2026

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Insider Activity

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#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Castagna, MichaelChief Executive OfficerDirectBuy31020262.59100,000259,0006,671,609Form
2Tross, Stuart AChief People & Workpl OfficerDirectSell10920266.3347,006297,5486,235,094Form
3Castagna, MichaelChief Executive OfficerDirectSell121920256.0165,804395,48215,053,800Form
4Castagna, MichaelChief Executive OfficerDirectSell121620256.0021,310127,86015,028,752Form
5Castagna, MichaelChief Executive OfficerDirectSell121620256.0020,806124,83615,028,752Form