Tearsheet

BioRestorative Therapies (BRTX)


Market Price (2/1/2026): $1.17 | Market Cap: $10.7 Mil
Sector: Health Care | Industry: Biotechnology

BioRestorative Therapies (BRTX)


Market Price (2/1/2026): $1.17
Market Cap: $10.7 Mil
Sector: Health Care
Industry: Biotechnology

Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.

0 Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -43%
Weak multi-year price returns
2Y Excs Rtn is -70%, 3Y Excs Rtn is -135%
Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -15 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -3785%
1 Megatrend and thematic drivers
Megatrends include Biotechnology & Genomics, Precision Medicine, and Aging Population & Chronic Disease. Themes include Cell Therapy, Show more.
  Weak revenue growth
Rev Chg QQuarterly Revenue Change % is -95%
2   Significant share based compensation
SBC/Rev LTMShare Based Compensation / Revenue (Sales), Last Twelve Months (LTM) is 796%
3   Not cash flow generative
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -2796%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -2809%
4   Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -126%
5   Key risks
BRTX key risks include [1] its dependence on an aggressive 69-74% annual growth rate to achieve profitability and [2] continued shareholder dilution from the need to fund its cash-burning operations.
0 Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -43%
1 Megatrend and thematic drivers
Megatrends include Biotechnology & Genomics, Precision Medicine, and Aging Population & Chronic Disease. Themes include Cell Therapy, Show more.
2 Weak multi-year price returns
2Y Excs Rtn is -70%, 3Y Excs Rtn is -135%
3 Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -15 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -3785%
4 Weak revenue growth
Rev Chg QQuarterly Revenue Change % is -95%
5 Significant share based compensation
SBC/Rev LTMShare Based Compensation / Revenue (Sales), Last Twelve Months (LTM) is 796%
6 Not cash flow generative
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -2796%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -2809%
7 Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -126%
8 Key risks
BRTX key risks include [1] its dependence on an aggressive 69-74% annual growth rate to achieve profitability and [2] continued shareholder dilution from the need to fund its cash-burning operations.

Valuation, Metrics & Events

Price Chart

Why The Stock Moved

Qualitative Assessment

AI Analysis | Feedback

BioRestorative Therapies (BRTX) stock has lost about 25% since 10/31/2025 because of the following key factors:

1. Dilutive Registered Direct Offering

BioRestorative Therapies announced a registered direct offering in early October 2025, selling common stock at $1.60 per share and issuing warrants with an exercise price of $2.75. This capital raise, while providing funds, likely led to stock dilution and an immediate 5% drop in the stock price upon announcement.

2. Deteriorating Financial Performance in Q3 2025

The company reported significantly weaker financial results for the third quarter ended September 30, 2025. Revenues plummeted to $11,800 from $233,600 in the prior year, primarily due to the timing of biocosmeceutical sales orders. Additionally, the net loss widened substantially to $3 million, or $0.33 per share, compared to a net loss of $1 million, or $0.13 per share, in the same period a year ago, reflecting increased operational losses.

Show more

Stock Movement Drivers

Fundamental Drivers

The -24.0% change in BRTX stock from 10/31/2025 to 2/1/2026 was primarily driven by a -36.6% change in the company's Total Revenues ($ Mil).
(LTM values as of)103120252012026Change
Stock Price ($)1.541.17-24.0%
Change Contribution By: 
Total Revenues ($ Mil)10-36.6%
P/S Multiple22.227.825.1%
Shares Outstanding (Mil)99-4.1%
Cumulative Contribution-24.0%

LTM = Last Twelve Months as of date shown

Market Drivers

10/31/2025 to 2/1/2026
ReturnCorrelation
BRTX-26.0% 
Market (SPY)1.5%38.7%
Sector (XLV)7.3%15.9%

Fundamental Drivers

The -20.4% change in BRTX stock from 7/31/2025 to 2/1/2026 was primarily driven by a -11.5% change in the company's P/S Multiple.
(LTM values as of)73120252012026Change
Stock Price ($)1.471.17-20.4%
Change Contribution By: 
Total Revenues ($ Mil)00-1.9%
P/S Multiple31.427.8-11.5%
Shares Outstanding (Mil)89-8.3%
Cumulative Contribution-20.4%

LTM = Last Twelve Months as of date shown

Market Drivers

7/31/2025 to 2/1/2026
ReturnCorrelation
BRTX-22.4% 
Market (SPY)9.8%35.1%
Sector (XLV)19.2%15.0%

Fundamental Drivers

The -50.8% change in BRTX stock from 1/31/2025 to 2/1/2026 was primarily driven by a -45.7% change in the company's P/S Multiple.
(LTM values as of)13120252012026Change
Stock Price ($)2.381.17-50.8%
Change Contribution By: 
Total Revenues ($ Mil)001.7%
P/S Multiple51.327.8-45.7%
Shares Outstanding (Mil)89-10.9%
Cumulative Contribution-50.8%

LTM = Last Twelve Months as of date shown

Market Drivers

1/31/2025 to 2/1/2026
ReturnCorrelation
BRTX-52.1% 
Market (SPY)16.0%31.4%
Sector (XLV)6.8%23.5%

Fundamental Drivers

The -60.2% change in BRTX stock from 1/31/2023 to 2/1/2026 was primarily driven by a -68.5% change in the company's P/S Multiple.
(LTM values as of)13120232012026Change
Stock Price ($)2.941.17-60.2%
Change Contribution By: 
Total Revenues ($ Mil)00216.6%
P/S Multiple88.427.8-68.5%
Shares Outstanding (Mil)49-60.0%
Cumulative Contribution-60.2%

LTM = Last Twelve Months as of date shown

Market Drivers

1/31/2023 to 2/1/2026
ReturnCorrelation
BRTX-61.2% 
Market (SPY)76.6%19.4%
Sector (XLV)21.4%14.7%

Return vs. Risk

Price Returns Compared

 202120222023202420252026Total [1]
Returns
BRTX Return2169900%-37%-37%-18%-18%-3%569900%
Peers Return6308%-27%40%9%46%-7%9651%
S&P 500 Return27%-19%24%23%16%2%86%

Monthly Win Rates [3]
BRTX Win Rate8%33%42%33%42%0% 
Peers Win Rate40%32%53%43%53%40% 
S&P 500 Win Rate75%42%67%75%67%100% 

Max Drawdowns [4]
BRTX Max Drawdown0%-43%-47%-34%-27%-6% 
Peers Max Drawdown-4%-65%-16%-34%-32%-11% 
S&P 500 Max Drawdown-1%-25%-1%-2%-15%-1% 


[1] Cumulative total returns since the beginning of 2021
[2] Peers: CELZ, VCEL, ORGO, LCTX, VKTX.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 1/30/2026 (YTD)

How Low Can It Go

Unique KeyEventBRTXS&P 500
2022 Inflation Shock2022 Inflation Shock  
2022 Inflation Shock% Loss% Loss-81.3%-25.4%
2022 Inflation Shock% Gain to Breakeven% Gain to Breakeven435.9%34.1%
2022 Inflation ShockTime to BreakevenTime to BreakevenNot Fully Recovered days464 days
2020 Covid Pandemic2020 Covid Pandemic  
2020 Covid Pandemic% Loss% Loss-99.2%-33.9%
2020 Covid Pandemic% Gain to Breakeven% Gain to Breakeven12500.0%51.3%
2020 Covid PandemicTime to BreakevenTime to Breakeven619 days148 days
2018 Correction2018 Correction  
2018 Correction% Loss% Loss-99.9%-19.8%
2018 Correction% Gain to Breakeven% Gain to Breakeven67900.0%24.7%
2018 CorrectionTime to BreakevenTime to Breakeven675 days120 days

Compare to CELZ, VCEL, ORGO, LCTX, VKTX

In The Past

BioRestorative Therapies's stock fell -81.3% during the 2022 Inflation Shock from a high on 11/12/2021. A -81.3% loss requires a 435.9% gain to breakeven.

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About BioRestorative Therapies (BRTX)

BioRestorative Therapies, Inc., a life sciences company, focuses on the development of regenerative medicine products and therapies using cell and tissue protocols primarily involving adult stem cells. The company's two core developmental programs relate to the treatment of disc/spine disease and metabolic disorders. Its disc/spine program (brtxDisc) includes a lead cell therapy candidate, BRTX-100, a product candidate formulated from autologous cultured mesenchymal stem cells collected from the patient's bone marrow, which has completed Phase 1 clinical trials for use in the non-surgical treatment of painful lumbosacral disc disorders. The company is also developing Metabolic Program (ThermoStem), a cell-based therapy candidate that is in preclinical stage to target obesity and metabolic disorders using brown adipose derived stem cells to generate brown adipose tissue. In addition, it provides investigational curved needle device designed to deliver cells and/or other therapeutic products or material to the spine and discs. BioRestorative Therapies, Inc. has a research and development agreement with Rohto Pharmaceutical Co., Ltd.; a research agreement with Pfizer, Inc.; and a research collaboration agreement with the University of Pennsylvania. The company was formerly known as Stem Cell Assurance, Inc. and changed its name to BioRestorative Therapies, Inc. in August 2011. BioRestorative Therapies, Inc. was incorporated in 1997 and is based in Melville, New York.

AI Analysis | Feedback

Here are 1-2 brief analogies for BioRestorative Therapies (BRTX):

  • Think of them as an early-stage Moderna, but focused on developing cell therapies for chronic conditions like back pain and metabolic disorders, rather than mRNA technology.
  • Imagine a nascent Pfizer, but entirely dedicated to developing cell-based therapies for chronic conditions like back pain, rather than a broad range of pharmaceutical drugs.

AI Analysis | Feedback

  • BRTX-100: An investigational autologous (patient's own) stem cell therapy for the treatment of chronic lumbar disc disease, currently in clinical trials.
  • ThermoStem® Program: A research and development program focused on brown adipose tissue-derived stem cell therapies for obesity and metabolic disorders.
  • Immuno-Stemâ„¢ Program: A research program exploring stem cell-based therapies for various autoimmune and inflammatory diseases.

AI Analysis | Feedback

BioRestorative Therapies (symbol: BRTX) is a clinical-stage biotechnology company focused on developing stem cell-based therapies. As such, the company does not currently have commercialized products or traditional major customers purchasing its therapies. Its primary activities are research and development, including conducting clinical trials to gain regulatory approval for its product candidates.

However, if its therapeutic products receive regulatory approval and become commercially available, the company would primarily sell to and serve individuals through the healthcare system. Based on its current product pipeline, the major categories of future customers would include:

  • Individuals suffering from chronic lumbar disc disease: These patients would be candidates for BRTX-100, an autologous mesenchymal stem cell therapy aimed at treating degenerative disc disease, a common cause of chronic back pain.
  • Individuals diagnosed with metabolic disorders, such as Type 2 diabetes: These patients would be candidates for BRTX-201, an allogeneic mesenchymal stem cell therapy in development to address metabolic conditions.

AI Analysis | Feedback

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AI Analysis | Feedback

Lance Alstodt, President, CEO and Chairman of the Board

Mr. Alstodt was appointed President, Chief Executive Officer, and Chairman of the Board of BioRestorative Therapies as of November 16, 2020. He brings over 25 years of experience in leading medical technology and life sciences companies in operations, capital raising, strategy, and mergers and acquisitions. Most recently, he was the Founder and CEO of MedVest Consulting Corporation, an advisory and capital firm focused exclusively within the healthcare sector. Prior to MedVest, Mr. Alstodt had a career as an investment banker with over 25 years of experience in healthcare investment banking, including mergers and acquisitions. His experience includes roles at J.P. Morgan Chase in the Global M&A Group, where he worked on acquisitions, leveraged buyouts, private and public financings, and exclusive sales. He also served as a Managing Director in the Healthcare Group and Global M&A Group at Bank of America Merrill Lynch, and as a Managing Director and Head of Medical Technology at Oppenheimer & Co.

Robert Kristal, Chief Financial Officer

Mr. Kristal was appointed Chief Financial Officer of BioRestorative Therapies in November 2021. He brings over 25 years of strategic and financial markets experience, including advising global public life sciences companies in corporate finance, operations management systems, and strategic collaborations. Mr. Kristal is an experienced Wall Street and Bay St. professional who has built teams in institutional sales and equity research. He most recently served as the Head of Research for H.C. Wainwright, where he grew their research product and presence in the biotech and biopharma space. Mr. Kristal has been involved in numerous transactions in investment and merchant banking and has extensive experience in providing strategic advice and dealing with investors and corporate management.

Francisco Silva, Chief Scientist & VP, R&D

Mr. Silva joined BioRestorative Therapies in April 2011 and serves as Vice President of Research and Development. He is responsible for all laboratory operations and the development and growth of the company's stem cell programs. Mr. Silva previously held the position of Chief Executive Officer at two companies focused on the commercialization of human-based biologics for research and therapeutic applications. From 2003 to 2007, he was the Vice President of Research and Development for PrimeGen Biotech LLC, where he focused on the development of cell-based platforms.

Crystal Romano, Head of Global Commercial Operations

Ms. Romano joined BioRestorative Therapies in October 2025 as Head of Global Commercial Operations. She has over 19 years of progressive leadership experience in the medical, aesthetics, and regenerative industries. Her expertise includes product development and innovation, commercialization, sales and account management, clinical and product training, and navigating patent and U.S. Food and Drug Administration (FDA) regulations. Before joining BioRestorative Therapies, Ms. Romano held pivotal roles at Cartessa and Lumenis, where she led medical aesthetics product innovation, development, and commercialization. Most recently, as Head of Innovation and Emerging Technologies at Cartessa, she successfully conceptualized, developed, and commercialized over 11 new products and a biologics line in under two years.

Adam D. Bergstein, Senior Vice President, Planning and Business Development

Mr. Bergstein was appointed Senior Vice President, Planning and Business Development at BioRestorative Therapies in January 2018. In this role, he was responsible for strategic planning, business development, and capital market activities. From 2008 until 2017, Mr. Bergstein founded and operated PharmaShield, an analytics company. Prior to that, from 1998 through 2006, he was a private equity investor in the healthcare and technology sectors.

AI Analysis | Feedback

BioRestorative Therapies (BRTX) faces several key business risks, primarily stemming from its status as a clinical-stage biotechnology company.
  1. Failure to Achieve Profitability: BioRestorative Therapies is currently a loss-making entity, with analysts projecting continued losses through 2026 and a potential breakeven in 2027. This profitability hinges on an aggressive annual growth rate of 69% to 74%, and a slower growth could significantly delay achieving profitability. The company reported a net loss of $9.0 million in its latest financial year, which broadened to a trailing-twelve-month loss of $11 million to $12 million.
  2. Clinical Development and Regulatory Approval Risk: As a regenerative medicine innovator, BioRestorative Therapies' success is highly dependent on the successful completion of clinical trials for its therapeutic candidates, particularly BRTX-100 for chronic lower back and cervical discogenic pain, and subsequent regulatory approvals. The outcomes of clinical trials are subject to numerous risks and uncertainties that could cause actual results to differ materially from projections, as cautioned in the company's SEC filings.
  3. Need for Additional Capital and Potential Dilution: While BioRestorative Therapies currently operates without debt, it is a cash-burning company that relies on shareholder funding and equity offerings to finance its ongoing research, development, and operational activities. The need for continuous financing to support its clinical programs and potential commercialization efforts presents a risk, as future offerings could dilute existing shareholders or may not be secured on favorable terms. For example, the company recently conducted a registered direct offering to strengthen its financial position.

AI Analysis | Feedback

The widespread and rapidly increasing adoption of GLP-1 receptor agonists (such as Wegovy, Ozempic, Zepbound, and Mounjaro) for weight management and metabolic health presents a significant emerging threat to BioRestorative Therapies' metabolic disorder program, particularly their brown adipose tissue (BAT) derived stem cell therapy for obesity and diabetes.

These pharmaceutical treatments have demonstrated unprecedented efficacy in achieving substantial weight loss and improving metabolic parameters. Their ease of administration (weekly injections) and growing market penetration are rapidly redefining the standard of care for obesity. This creates a challenging environment for any new, more complex, or less established therapeutic approaches, including cell therapies, that aim to address the same conditions. The high efficacy and increasing accessibility of GLP-1 agonists could significantly diminish the market opportunity and patient/physician interest in alternative obesity treatments, regardless of their distinct mechanisms of action.

AI Analysis | Feedback

BioRestorative Therapies (BRTX) has two primary product development programs: the Disc/Spine Program featuring BRTX-100 and the Metabolic Program featuring ThermoStem®.

Disc/Spine Program (BRTX-100)

The BRTX-100 therapy, an autologous mesenchymal stem cell (MSC) treatment, targets chronic lumbar disc disease (cLDD) and chronic cervical discogenic pain (cCDP). The broader market for conditions treated by mesenchymal stem cell therapy, including orthopedic and musculoskeletal disorders, was estimated at USD 80.9 million globally in 2024 and is projected to reach USD 337.36 million globally by 2034, growing at a CAGR of 23.5% from 2025 to 2030. Within this, the U.S. market size for mesenchymal stem cells is projected to reach USD 65.9 million by 2034. An older report from 2016 indicates that surgical procedures for degenerative disc disease in the U.S. account for $40 billion annually, with 32 million American adults diagnosed and treated for disc degeneration.

Metabolic Program (ThermoStem®)

The ThermoStem® platform focuses on cell-based therapies for obesity and metabolic disorders. The global obesity market is projected to exceed $100 billion annually by the end of the decade (by 2030), primarily driven by the demand for GLP-1 therapies. More specifically, the global obesity therapeutics market was valued at US$ 11.03 billion in 2024 and is expected to reach US$ 63.75 billion by 2033, with a CAGR of 21.6% during the forecast period 2025-2033. North America holds a significant share, dominating the global obesity therapeutics market with a 48.5% revenue share in 2024. Another report valued the global obesity treatment market at USD 15.92 billion in 2024, projected to reach USD 60.53 billion by 2030, growing at a CAGR of 22.31% from 2025 to 2030. North America also led this market with a 73.39% revenue share in 2024. For general metabolic disorders, the global therapeutics market was valued at USD 74.40 billion in 2024 and is anticipated to grow at a CAGR of 7.68% through 2030, with North America being the largest regional market in 2024.

BioCosmeceutical Platform

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AI Analysis | Feedback

Expected Drivers of Future Revenue Growth for BioRestorative Therapies (BRTX)

Over the next 2-3 years, BioRestorative Therapies (NASDAQ: BRTX) is anticipated to drive future revenue growth through several key initiatives, primarily centered on the commercialization of its proprietary therapeutic products and expansion into new markets. Here are 3-5 expected drivers: * Commercialization of BioCosmeceutical Products: BioRestorative Therapies has already begun generating revenue from its BioCosmeceutical platform. The company reported a 240% increase in revenues in Q2 2025, primarily driven by strong sales in this segment. A transformative five-year agreement with Cartessa, a leader in medical aesthetics technology, involves BioRestorative supplying its initial commercial cell-based biologic product. This partnership is expected to provide financial flexibility and reduce dependence on capital markets for future funding, with intentions to expand into a broader family of cell-based biologic aesthetic products and therapeutics. * Advancement and Potential Approval of BRTX-100 for Chronic Lumbar Disc Disease (cLDD): The company's lead cell therapy candidate, BRTX-100, is currently in a Phase 2 clinical trial for chronic lower back pain arising from degenerative disc disease. Preliminary blinded data from the trial has shown promising results, with a significant percentage of subjects experiencing over 50% improvement in both function and pain. The FDA has granted Fast Track designation for BRTX-100 for cLDD, reflecting positive preliminary safety and efficacy data. Successful completion of the Phase 2 trial and progression towards regulatory approval and commercialization would open up access to the substantial chronic back pain market, which is valued at over $150 billion. * Expansion of BRTX-100 Indications to Chronic Cervical Discogenic Pain (cCDP): In February 2025, the FDA cleared BioRestorative Therapies' Investigational New Drug (IND) application for BRTX-100 for the treatment of chronic cervical discogenic pain (cCDP). This expands the potential market for BRTX-100 beyond lumbar disc disease to include chronic neck pain, further broadening the product's revenue-generating potential upon successful clinical development and approval. * Development of ThermoStem® Program for Metabolic Disorders: BioRestorative Therapies is developing cell-based therapy candidates under its ThermoStem® program to target obesity and metabolic disorders. This program utilizes brown adipose (fat) derived stem cells to generate brown adipose tissue, which is intended to regulate metabolic homeostasis. Preclinical research suggests that increased brown fat may lead to additional caloric burning and reduced glucose and lipid levels. Successful development and commercialization of these therapies could tap into the multi-billion dollar market for obesity and metabolic disorder treatments. * Strategic Partnerships and Commercial Leadership: BioRestorative Therapies is actively pursuing partnerships to expand its pipeline and accelerate regulatory approval. The company has also strengthened its commercial leadership with the appointment of Crystal Romano as Head of Global Commercial Operations, aiming to accelerate the growth of its cell-based product portfolio. These strategic moves are intended to enhance operational efficiency and expand market reach, contributing to future revenue growth.

AI Analysis | Feedback

Share Repurchases

  • BioRestorative Therapies authorized a $2 million stock repurchase program on June 17, 2025, allowing the company to buy back shares through June 16, 2026.

Share Issuance

  • On October 6, 2025, BioRestorative Therapies agreed to sell 678,125 common shares at $1.60 per share in a registered direct offering, generating gross proceeds of $1.085 million.
  • Concurrently, the company issued unregistered warrants to purchase up to 508,594 shares of common stock at an exercise price of $2.75 per share, exercisable for five years starting six months after issuance.
  • For the three months ended March 31, 2025, the company reported net proceeds of $901,610 from the issuance and sale of 492,087 shares of common stock.

Inbound Investments

  • The $1.085 million registered direct offering in October 2025 involved "accredited and/or institutional investors," including the company's largest institutional shareholder, providing new capital to the company.

Capital Expenditures

  • Net proceeds from the October 2025 offering are designated to fund BRTX-100 clinical trials, ThermoStem preclinical research and development, the development of its commercial biocosmeceuticals platform, and general corporate purposes.

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Unique Key

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Peer Comparisons

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Financials

BRTXCELZVCELORGOLCTXVKTXMedian
NameBioResto.Creative.Vericel Organoge.Lineage .Viking T. 
Mkt Price1.172.0236.004.011.4729.123.01
Mkt Cap0.00.01.80.50.33.30.4
Rev LTM002594651106
Op Inc LTM-15-671-20-275-10
FCF LTM-11-620-52-21-225-16
FCF 3Y Avg-8-77-17-25-122-13
CFO LTM-11-659-39-20-225-16
CFO 3Y Avg-8-7461-25-122-8

Growth & Margins

BRTXCELZVCELORGOLCTXVKTXMedian
NameBioResto.Creative.Vericel Organoge.Lineage .Viking T. 
Rev Chg LTM1.7%-45.5%14.1%2.1%24.1%-2.1%
Rev Chg 3Y Avg66.3%-61.0%17.6%0.1%-4.2%-0.1%
Rev Chg Q-94.9%-16.6%30.7%-2.6%-7.0%
QoQ Delta Rev Chg LTM-36.6%0.0%3.9%8.2%-0.9%-0.0%
Op Mgn LTM-3,785.1%-101,379.4%2.7%0.2%-188.1%--188.1%
Op Mgn 3Y Avg-6,555.8%-64,574.8%-1.6%2.5%-244.6%--244.6%
QoQ Delta Op Mgn LTM-1,622.2%-2,722.7%2.3%3.6%-1.2%--1.2%
CFO/Rev LTM-2,796.5%-97,807.1%22.9%-8.3%-188.5%--188.5%
CFO/Rev 3Y Avg-3,246.0%-61,677.9%20.2%0.3%-267.1%--267.1%
FCF/Rev LTM-2,809.2%-97,807.1%7.9%-11.1%-193.0%--193.0%
FCF/Rev 3Y Avg-3,343.2%-61,677.9%2.9%-3.7%-271.9%--271.9%

Valuation

BRTXCELZVCELORGOLCTXVKTXMedian
NameBioResto.Creative.Vericel Organoge.Lineage .Viking T. 
Mkt Cap0.00.01.80.50.33.30.4
P/S27.8868.87.01.131.0-27.8
P/EBIT-0.7-0.9131.2611.5-16.5-11.9-0.8
P/E-0.8-0.9138.9506.3-5.0-13.8-0.9
P/CFO-1.0-0.930.7-13.1-16.4-14.6-7.1
Total Yield-121.9%-114.4%0.7%0.2%-20.0%-7.3%-13.6%
Dividend Yield0.0%0.0%0.0%0.0%0.0%0.0%0.0%
FCF Yield 3Y Avg-83.7%-142.2%0.4%-2.5%-15.4%-3.6%-9.5%
D/E0.00.00.10.10.00.00.0
Net D/E-0.4-1.0-0.0-0.0-0.1-0.2-0.2

Returns

BRTXCELZVCELORGOLCTXVKTXMedian
NameBioResto.Creative.Vericel Organoge.Lineage .Viking T. 
1M Rtn-4.1%2.5%1.1%-13.5%-10.7%-17.8%-7.4%
3M Rtn-24.0%-36.3%2.7%-5.6%-23.7%-23.5%-23.6%
6M Rtn-17.0%-29.6%1.0%-11.1%48.7%-10.9%-11.0%
12M Rtn-50.8%-35.5%-38.5%9.0%143.9%-11.1%-23.3%
3Y Rtn-62.6%-62.9%14.9%36.9%4.6%216.9%9.8%
1M Excs Rtn-0.2%9.2%-2.6%-23.2%-9.1%-18.2%-5.8%
3M Excs Rtn-25.7%-47.0%2.5%-4.5%-15.0%-18.0%-16.5%
6M Excs Rtn-30.1%-36.8%-6.4%-22.7%34.3%-20.1%-21.4%
12M Excs Rtn-65.5%-52.0%-53.9%-9.4%128.4%-27.8%-39.9%
3Y Excs Rtn-136.4%-134.3%-43.8%-11.3%-74.4%168.4%-59.1%

Comparison Analyses

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Financials

Price Behavior

Price Behavior
Market Price$1.14 
Market Cap ($ Bil)0.0 
First Trading Date09/19/2011 
Distance from 52W High-54.2% 
   50 Days200 Days
DMA Price$1.14$1.49
DMA Trenddowndown
Distance from DMA0.1%-23.4%
 3M1YR
Volatility75.0%70.1%
Downside Capture284.31190.42
Upside Capture85.6285.97
Correlation (SPY)38.9%31.3%
BRTX Betas & Captures as of 1/31/2026

 1M2M3M6M1Y3Y
Beta0.330.642.541.971.141.17
Up Beta2.191.930.190.450.661.05
Down Beta2.370.805.353.511.431.59
Up Capture-178%75%85%119%85%36%
Bmk +ve Days11223471142430
Stock +ve Days8182353107336
Down Capture-195%-25%249%201%142%106%
Bmk -ve Days9192754109321
Stock -ve Days10162955120366

[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with BRTX
BRTX-49.4%69.8%-0.69-
Sector ETF (XLV)7.7%17.2%0.2723.5%
Equity (SPY)16.1%19.2%0.6531.3%
Gold (GLD)76.5%23.4%2.38-0.6%
Commodities (DBC)11.1%15.9%0.48-1.2%
Real Estate (VNQ)5.3%16.5%0.1422.2%
Bitcoin (BTCUSD)-18.9%39.9%-0.4313.9%

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Based On 5-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with BRTX
BRTX-29.9%90.5%-0.04-
Sector ETF (XLV)7.1%14.5%0.3115.6%
Equity (SPY)14.0%17.1%0.6520.3%
Gold (GLD)20.8%16.5%1.032.9%
Commodities (DBC)12.2%18.8%0.530.6%
Real Estate (VNQ)4.8%18.8%0.1613.1%
Bitcoin (BTCUSD)21.1%57.5%0.569.9%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 10-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with BRTX
BRTX-53.3%219.8%-0.12-
Sector ETF (XLV)10.4%16.6%0.522.7%
Equity (SPY)15.6%17.9%0.754.5%
Gold (GLD)15.6%15.3%0.853.3%
Commodities (DBC)8.5%17.6%0.401.4%
Real Estate (VNQ)5.9%20.8%0.252.9%
Bitcoin (BTCUSD)71.5%66.4%1.114.7%

Smart multi-asset allocation framework can stack odds in your favor. Learn How

Short Interest

Short Interest: As Of Date1152026
Short Interest: Shares Quantity0.1 Mil
Short Interest: % Change Since 12312025-2.8%
Average Daily Volume0.0 Mil
Days-to-Cover Short Interest5.4 days
Basic Shares Quantity9.1 Mil
Short % of Basic Shares1.5%

Earnings Returns History

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 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
11/12/2025-9.4%3.6%-19.6%
8/12/20252.0%2.4%8.8%
3/27/2025-1.1%-1.6%-7.1%
11/13/2024-1.9%-9.1%-5.8%
8/6/2024-4.3%2.2%9.4%
SUMMARY STATS   
# Positive132
# Negative423
Median Positive2.0%2.4%9.1%
Median Negative-3.1%-5.4%-7.1%
Max Positive2.0%3.6%9.4%
Max Negative-9.4%-9.1%-19.6%

SEC Filings

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Report DateFiling DateFiling
09/30/202511/12/202510-Q
06/30/202508/12/202510-Q
03/31/202505/14/202510-Q
12/31/202403/28/202510-K
09/30/202411/12/202410-Q
06/30/202408/13/202410-Q
03/31/202406/11/202410-Q
12/31/202304/01/202410-K
09/30/202311/13/202310-Q
06/30/202308/11/202310-Q
03/31/202305/12/202310-Q
12/31/202203/27/202310-K
09/30/202211/14/202210-Q
06/30/202208/15/202210-Q
03/31/202205/16/202210-Q
12/31/202103/30/202210-K