Market Movers | Winners: WSHP, SGBX, SEMR | Losers: IVP, AGIO, TPST

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On Wednesday, November 19, markets rallied broadly, with the S&P 500 rising 0.38%, the Dow 30 rising 0.10%, and the Nasdaq 100 rising 0.56%. While many stocks participated in the rally, some lagged behind.
 

List of Market Winners

The following table shows the list of 10 stocks that generated the highest returns on the last trading day:
 

# Ticker Company Name 1-D
Returns
YTD
Returns
1 WSHP WeShop 506.1% 562.0%
2 SGBX Safe & Green 78.0% -80.2%
3 SEMR SEMrush 74.0% -1.0%
4 NUVB Nuvation Bio 49.0% 168.8%
5 CABR Caring Brands 40.0% -9.2%
6 SGML Sigma Lithium 33.3% -7.7%
7 ZYXI Zynex 32.1% -93.1%
8 LNAI Lunai Bioworks 29.3% 79.5%
9 XCUR Exicure 27.1% -65.3%
10 ANNX Annexon 26.9% -20.9%

 
List of Market Losers

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On the other hand, the following table shows the list of 10 stocks that generated the lowest returns:
 

# Ticker Company Name 1-D
Returns
YTD
Returns
1 IVP Inspire Veterinary Partners -61.1% -97.8%
2 AGIO Agios Pharmaceuticals -50.9% -32.0%
3 TPST Tempest Therapeutics -48.6% -56.2%
4 MIGI Mawson Infrastructure -40.0% -64.0%
5 CARV Carver Bancorp -39.9% -1.6%
6 NCPL Netcapital -37.1% -49.5%
7 MTNB Matinas BioPharma -31.5% 58.5%
8 KTTA Pasithea Therapeutics -27.9% -84.9%
9 SPRU Spruce Power -27.1% 46.8%
10 SEGG Lottery.com -24.6% -72.1%

 
Why does this matter? Significant stock moves – up or down – deserve your attention. Sharp declines in fundamentally strong names can offer smart buying opportunities. And when momentum aligns with solid fundamentals, riding the trend can be highly rewarding.

You can’t predict what happens to individual stocks, but you can prepare. See how the Trefis High Quality Portfolio helps you.

Movers – Last One Week

Analysing over the last one week (5 trading days), markets declined across the board, with the S&P 500 falling 3.05%, the Dow 30 falling 4.39%, and the Nasdaq 100 falling 3.44%. Although broad pressure was felt, a few stocks managed to outperform.
 
List of 1-Week Market Winners

The following table shows the list of 10 stocks that generated the highest returns over the last week:
 

# Ticker Company Name 1-W
Returns
YTD
Returns
1 ASNS Actelis Networks 566.7% -75.3%
2 MRSN Mersana Therapeutics 211.3% -22.8%
3 SGBX Safe & Green 154.0% -80.2%
4 OLMA Olema Pharmaceuticals 141.1% 233.3%
5 CDTX Cidara Therapeutics 104.5% 714.8%
6 CNTB Connect Biopharma 95.7% 128.3%
7 MCRB Seres Therapeutics 78.8% 72.3%
8 SGML Sigma Lithium 77.4% -7.7%
9 BCAB BioAtla 68.7% 96.2%
10 LNAI Lunai Bioworks 63.8% 79.5%

 
List of 1-Week Market Losers

Similarly, the following table shows the 10 stocks that were at the bottom in terms of returns:
 

# Ticker Company Name 1-W
Returns
YTD
Returns
1 IVP Inspire Veterinary Partners -84.8% -97.8%
2 RPGL Republic Power -82.6% -90.8%
3 KRRO Korro Bio -79.6% -83.2%
4 CABR Caring Brands -75.8% -9.2%
5 MVO MV Oil Trust -71.2% -82.1%
6 APLT Applied Therapeutics -68.7% -66.7%
7 MIGI Mawson Infrastructure -54.2% -64.0%
8 NVNO enVVeno Medical -54.0% -89.5%
9 TSSI TSS -53.2% -36.3%
10 FOXX Foxx Development -49.6% -70.1%

 
Movers – Last One Month

On a slightly wider timeline over the last one month, selling pressure hit the S&P 500 falling 1.38%, the Dow 30 falling 1.67%, and the Nasdaq 100 falling 1.94%. Declines were common, though some stocks held steady.
 
List of 1-Month Market Winners

The following table shows the 10 stocks that generated the maximum returns over the last one month:
 

# Ticker Company Name 1-M
Returns
YTD
Returns
1 Q Qnity Electronics 1065.7% 1065.7%
2 CYPH Cypherpunk Technologies 505.4% 2.3%
3 TERN Terns Pharmaceuticals 234.0% 389.5%
4 MRSN Mersana Therapeutics 174.7% -22.8%
5 FRGE Forge Global 164.3% 215.5%
6 SGBX Safe & Green 156.1% -80.2%
7 VTYX Ventyx Biosciences 151.9% 332.4%
8 SOHO Sotherly Hotels 144.1% 131.9%
9 GLTO Galecto 138.3% 337.2%
10 OLMA Olema Pharmaceuticals 134.7% 233.3%

 
List of 1-Month Market Losers

In the same period, these 10 stocks were at the bottom in terms of returns:
 

# Ticker Company Name 1-M
Returns
YTD
Returns
1 FPAY FlexShopper -95.9% -99.6%
2 SOND Sonder -91.5% -97.1%
3 FUSE Fusemachines -91.2% -95.9%
4 ADTX Aditxt -89.5% -99.9%
5 IVP Inspire Veterinary Partners -89.1% -97.8%
6 KRRO Korro Bio -84.5% -83.2%
7 AMZE Amaze -81.7% -98.0%
8 PMI Picard Medical -81.2% 3661.9%
9 APLT Applied Therapeutics -80.3% -66.7%
10 CMND Clearmind Medicine -80.3% -85.3%

 

Picking winners on a consistent basis is not an easy task – especially given the volatility associated with a single stock. Instead, the Trefis High Quality (HQ) Portfolio, with a collection of 30 stocks, has a track record of comfortably outperforming its benchmark that includes all 3 — the S&P 500, S&P mid-cap, and Russell 2000 indices. Why is that? As a group, HQ Portfolio stocks provided better returns with less risk versus the benchmark index; less of a roller-coaster ride, as evident in HQ Portfolio performance metrics.