Tearsheet

Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.

0

Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -32%

Valuation becoming less expensive
P/S 6M Chg %Price/Sales change over 6 months. Declining P/S indicates valuation has become less expensive. is -76%

Megatrend and thematic drivers
Megatrends include Precision Medicine. Themes include Biopharmaceutical R&D, and Targeted Therapies.

Weak multi-year price returns
2Y Excs Rtn is -5.6%

Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -66 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -28427%

Expensive valuation multiples
P/SPrice/Sales ratio is 604x

Stock price has recently run up significantly
12M Rtn12 month market price return is 196%

Weak revenue growth
Rev Chg LTMRevenue Change % Last Twelve Months (LTM) is -99%

Significant share based compensation
SBC/Rev LTMShare Based Compensation / Revenue (Sales), Last Twelve Months (LTM) is 1709%

Not cash flow generative
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -24572%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -24723%

Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -50%

High stock price volatility
Vol 12M is 105%

Key risks
CNTB key risks include [1] potential failure to develop and approve its pipeline, Show more.

0 Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -32%
1 Valuation becoming less expensive
P/S 6M Chg %Price/Sales change over 6 months. Declining P/S indicates valuation has become less expensive. is -76%
2 Megatrend and thematic drivers
Megatrends include Precision Medicine. Themes include Biopharmaceutical R&D, and Targeted Therapies.
3 Weak multi-year price returns
2Y Excs Rtn is -5.6%
4 Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -66 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -28427%
5 Expensive valuation multiples
P/SPrice/Sales ratio is 604x
6 Stock price has recently run up significantly
12M Rtn12 month market price return is 196%
7 Weak revenue growth
Rev Chg LTMRevenue Change % Last Twelve Months (LTM) is -99%
8 Significant share based compensation
SBC/Rev LTMShare Based Compensation / Revenue (Sales), Last Twelve Months (LTM) is 1709%
9 Not cash flow generative
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -24572%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -24723%
10 Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -50%
11 High stock price volatility
Vol 12M is 105%
12 Key risks
CNTB key risks include [1] potential failure to develop and approve its pipeline, Show more.

Valuation, Metrics & Events

Price Chart

Why The Stock Moved

Qualitative Assessment

AI Analysis | Feedback

Updated on 5/1/2026
Connect Biopharma (CNTB) stock has remained largely at the same level since 2/28/2026 because of the following key factors:

1. Ongoing clinical trial progress and positive interim data for rademikibart in asthma and COPD. Connect Biopharma continued advancing its lead asset, rademikibart, with ongoing enrollment in the Phase 2 Seabreeze STAT studies for acute exacerbations in asthma and chronic obstructive pulmonary disease (COPD), with topline data anticipated mid-2026. An independent Data Monitoring Committee (DMC) completed an interim review in April 2026, recommending no changes to the sample size and confirming no safety concerns for these studies, indicating smooth trial progression. Additionally, positive topline data from a Phase 1 intravenous (IV) rademikibart study, announced in March 2026, demonstrated rapid onset and sustained lung function improvement.

2. Successful private placement extended cash runway. The company completed a private placement financing on March 31, 2026, raising $20.2 million in gross proceeds and an estimated $18.6 million in net proceeds. This capital injection bolstered cash and cash equivalents to $46.0 million as of March 31, 2026, and is expected to fund operations into the second half of 2027. This secured funding helps alleviate near-term financial concerns, providing stability to the stock.

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Stock Movement Drivers

Fundamental Drivers

The 0.8% change in CNTB stock from 2/28/2026 to 5/31/2026 was primarily driven by a 0.0% change in the company's Total Revenues ($ Mil).
(LTM values as of)22820265312026Change
Stock Price ($)2.472.490.8%
Change Contribution By: 
Total Revenues ($ Mil)00.0%
P/S Multiple604.30.0%
Shares Outstanding (Mil)5557-2.3%
Cumulative Contribution0.0%

LTM = Last Twelve Months as of date shown

Market Drivers

2/28/2026 to 5/31/2026
ReturnCorrelation
CNTB0.8% 
Market (SPY)10.6%3.9%
Sector (XLV)-6.3%3.0%

Fundamental Drivers

The -11.4% change in CNTB stock from 11/30/2025 to 5/31/2026 was primarily driven by a -2.3% change in the company's Shares Outstanding (Mil).
(LTM values as of)113020255312026Change
Stock Price ($)2.812.49-11.4%
Change Contribution By: 
Total Revenues ($ Mil)00.0%
P/S Multiple604.30.0%
Shares Outstanding (Mil)5557-2.3%
Cumulative Contribution0.0%

LTM = Last Twelve Months as of date shown

Market Drivers

11/30/2025 to 5/31/2026
ReturnCorrelation
CNTB-11.4% 
Market (SPY)11.3%8.7%
Sector (XLV)-4.4%1.7%

Fundamental Drivers

The 196.4% change in CNTB stock from 5/31/2025 to 5/31/2026 was primarily driven by a 0.0% change in the company's Total Revenues ($ Mil).
(LTM values as of)53120255312026Change
Stock Price ($)0.842.49196.4%
Change Contribution By: 
Total Revenues ($ Mil)00.0%
P/S Multiple604.30.0%
Shares Outstanding (Mil)5557-2.6%
Cumulative Contribution0.0%

LTM = Last Twelve Months as of date shown

Market Drivers

5/31/2025 to 5/31/2026
ReturnCorrelation
CNTB196.4% 
Market (SPY)29.8%-2.2%
Sector (XLV)14.7%-1.0%

Fundamental Drivers

null
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Market Drivers

5/31/2023 to 5/31/2026
ReturnCorrelation
CNTB129.7% 
Market (SPY)88.1%7.0%
Sector (XLV)22.9%4.7%

Return vs. Risk

Price Returns Compared

 202120222023202420252026Total [1]
Returns
CNTB Return-72%-83%36%17%104%-16%-87%
Peers Return23%20%15%7%31%-3%133%
S&P 500 Return27%-19%24%23%16%10%101%

Monthly Win Rates [3]
CNTB Win Rate60%25%58%42%67%40% 
Peers Win Rate57%63%57%57%60%48% 
S&P 500 Win Rate75%42%67%75%67%60% 

Max Drawdowns [4]
CNTB Max Drawdown--91%-66%-57%-60%-41% 
Peers Max Drawdown-22%-19%-22%-26%-27%-19% 
S&P 500 Max Drawdown-5%-25%-10%-8%-19%-9% 


[1] Cumulative total returns since the beginning of 2021
[2] Peers: REGN, AMGN, LLY, ABBV, INCY.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 5/29/2026 (YTD)

How Low Can It Go

EventCNTBS&P 500
2025 US Tariff Shock
  % Loss-40.2%-18.8%
  % Gain to Breakeven67.4%23.1%
  Time to Breakeven74 days79 days
2024 Yen Carry Trade Unwind
  % Loss-16.8%-7.8%
  % Gain to Breakeven20.2%8.5%
  Time to Breakeven24 days18 days
Summer-Fall 2023 Five Percent Yield Shock
  % Loss-36.7%-9.5%
  % Gain to Breakeven58.0%10.5%
  Time to Breakeven19 days24 days
2023 SVB Regional Banking Crisis
  % Loss-25.5%-6.7%
  % Gain to Breakeven34.1%7.1%
  Time to Breakeven14 days31 days

Compare to REGN, AMGN, LLY, ABBV, INCY

In The Past

Connect Biopharma's stock fell -40.2% during the 2025 US Tariff Shock. Such a loss loss requires a 67.4% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

EventCNTBS&P 500
2025 US Tariff Shock
  % Loss-40.2%-18.8%
  % Gain to Breakeven67.4%23.1%
  Time to Breakeven74 days79 days
Summer-Fall 2023 Five Percent Yield Shock
  % Loss-36.7%-9.5%
  % Gain to Breakeven58.0%10.5%
  Time to Breakeven19 days24 days
2023 SVB Regional Banking Crisis
  % Loss-25.5%-6.7%
  % Gain to Breakeven34.1%7.1%
  Time to Breakeven14 days31 days

Compare to REGN, AMGN, LLY, ABBV, INCY

In The Past

Connect Biopharma's stock fell -40.2% during the 2025 US Tariff Shock. Such a loss loss requires a 67.4% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

About Connect Biopharma (CNTB)

Connect Biopharma Holdings Limited, a clinical-stage biopharmaceutical company, focuses on the discovery and development of immune modulators for the treatment of serious autoimmune diseases and inflammation. The company's lead product candidate is CBP-201, an anti-interleukin-4 receptor alpha antibody, which is in Phase IIb clinical trial for the treatment of inflammatory allergic diseases, such as atopic dermatitis, asthma, and chronic rhinosinusitis with nasal polyps. Its products also comprise CBP-307, a small molecule modulator of sphingosine 1-phosphate receptor 1, a regulator of T cell mobilization out of lymph nodes into the periphery that is in Phase II for the treatment of autoimmune-related inflammation diseases; CBP-174, a small molecule histamine receptor 3 antagonist for oral administration, which is in a preclinical stage to treat chronic itch associated with skin inflammation; and CBP-233, a preclinical stage humanized antibody against interleukin-33, a cytokine involved in T helper 2 inflammation. The company was founded in 2012 and is headquartered in Taicang, China.

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An early-stage Sanofi or Regeneron, aiming to develop the next big drug for allergic and autoimmune diseases, much like Dupixent.

A clinical-stage AbbVie or Amgen, focused on discovering new treatments for autoimmune diseases.

AI Analysis | Feedback

  • CBP-201: An anti-interleukin-4 receptor alpha antibody in Phase IIb clinical trials for inflammatory allergic diseases like atopic dermatitis, asthma, and chronic rhinosinusitis with nasal polyps.
  • CBP-307: A small molecule modulator of sphingosine 1-phosphate receptor 1 in Phase II for autoimmune-related inflammation diseases.
  • CBP-174: A small molecule histamine receptor 3 antagonist in preclinical stage for treating chronic itch associated with skin inflammation.
  • CBP-233: A humanized antibody against interleukin-33 in preclinical stage for T helper 2 inflammation.

AI Analysis | Feedback

Connect Biopharma Holdings Limited (CNTB) is a clinical-stage biopharmaceutical company focused on the discovery and development of immune modulators. As described, their product candidates are currently in various stages of clinical trials (Phase IIb, Phase II, and preclinical stage) and are not yet approved for commercial sale. Therefore, Connect Biopharma does not have major customers in the traditional sense, as they are not currently selling commercial products to individuals or other companies.

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Supplier Name Symbol
WuXi Biologics (Cayman) Inc. 2269.HK
WuXi AppTec Co., Ltd. 2359.HK
Pharmaron (Beijing) Co., Ltd. 2268.HK
Lonza Group AG LONN.SW

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Barry Quart, Pharm.D. Chief Executive Officer and Director

Barry Quart brings over three decades of experience in the biotechnology and pharmaceutical sectors. He has personally led several early-stage biotech companies through late-stage clinical development and regulatory strategy, resulting in nine U.S. Food and Drug Administration (FDA) approved drugs. Prior to joining Connect Biopharma in June 2024, Dr. Quart served as CEO at Heron Therapeutics, where he oversaw the development and approval of four drugs. He also co-founded Ardea Biosciences, Inc. in 2006, leading it as President and CEO through its acquisition by AstraZeneca PLC in 2012.

David Szekeres President

David Szekeres is an experienced life science executive with a strong background in operational, commercial, corporate development/strategy, and legal expertise. He was appointed President of Connect Biopharma in June 2024. Previously, Mr. Szekeres served as Executive Vice President and Chief Operating Officer of Heron Therapeutics. His prior roles also include Chief Business Officer and General Counsel of Regulus Therapeutics and Head of Mergers & Acquisitions at Life Technologies Corporation.

Kimberly J. Manhard Chief Development Officer

Kimberly J. Manhard has over 25 years of experience in drug development, regulatory affairs, and pharmaceutical operations, and has been instrumental in the development and approval of eight drugs across multiple therapeutic categories. She previously served as Executive Vice President, Drug Development, and director of Heron Therapeutics, where she played a key role in the development and regulatory approvals of oncology care products. Prior to Heron, she was Senior Vice President of Regulatory Affairs and Development Operations at Ardea Biosciences, Inc., which was acquired by AstraZeneca. Her experience also includes regulatory positions at Exelixis, Agouron Pharmaceuticals, Bristol-Myers Squibb Company, and Eli Lilly and Company.

Lisa Peraza Senior Vice President, Finance

Lisa Peraza was appointed Vice President, Finance, for Connect Biopharma, effective August 12, 2024. She is a licensed Certified Public Accountant (C.P.A.) and has a background at Heron Therapeutics.

Jeff Cohn, J.D. General Counsel and Corporate Secretary

Jeff Cohn serves as the General Counsel and Corporate Secretary for Connect Biopharma.

AI Analysis | Feedback

Connect Biopharma (CNTB) faces several key risks inherent to its nature as a clinical-stage biopharmaceutical company. These risks are primarily associated with the lengthy, costly, and uncertain process of drug development and commercialization.

  1. Clinical Trial Failure Risk
    Connect Biopharma's most advanced product candidates, CBP-201 and CBP-307, are in Phase II/IIb clinical trials. CBP-201, an anti-interleukin-4 receptor alpha antibody, is in Phase IIb for inflammatory allergic diseases, including atopic dermatitis, asthma, and chronic rhinosinusitis with nasal polyps. It has shown positive results in a global Phase 2b trial for atopic dermatitis and a China-specific pivotal trial is ongoing with top-line results anticipated. CBP-307, a small molecule modulator of sphingosine 1-phosphate receptor 1 (S1P1), is in Phase II for autoimmune-related inflammation diseases. While CBP-307 has completed enrollment for its Phase 2 ulcerative colitis trial, and some secondary endpoints were met, the primary endpoint was not met in the 12-week induction phase. The success of these trials is critical, as clinical trials can fail at any stage due to lack of efficacy, safety concerns, or other issues. A failure would result in significant financial losses and could jeopardize the company's future.
  2. Regulatory Approval Risk
    Even if Connect Biopharma's clinical trials demonstrate positive results, there is no guarantee that its product candidates will receive regulatory approval from agencies such as the FDA or China's National Medical Products Administration (NMPA). The regulatory approval process is rigorous and can be unpredictable, potentially requiring additional studies, leading to delays, or even outright rejection. Connect Biopharma aims for a potential NDA approval for CBP-201 in China as early as 2025. Delays or failure to obtain regulatory approvals would significantly hinder the company's ability to commercialize its drugs and generate revenue.
  3. Intense Competition
    Connect Biopharma operates in highly competitive therapeutic areas. For CBP-201, targeting the IL-4Rα pathway, there is established competition, most notably Dupixent (dupilumab) developed by Sanofi and Regeneron, which is already approved for atopic dermatitis and asthma and has set a high standard for efficacy and safety. Connect Biopharma's rademikibart (CBP-201) is being positioned as a next-generation IL-4Rα antibody with potential for differentiated efficacy and safety. Similarly, for CBP-307, which is an S1P1 modulator, the market for autoimmune diseases already includes approved S1P receptor modulators like fingolimod and ozanimod, as well as numerous other drugs in development. The competitive landscape means Connect Biopharma must demonstrate superior efficacy, safety, or other advantages to capture market share.

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The primary clear emerging threat for Connect Biopharma is the intense competition from already established and highly successful pharmaceutical products targeting the same mechanisms and indications as their lead product candidate, CBP-201. Specifically, CBP-201, an anti-interleukin-4 receptor alpha antibody in Phase IIb clinical trials for atopic dermatitis, asthma, and chronic rhinosinusitis with nasal polyps, faces a significant challenge from Dupilumab (Dupixent), developed by Sanofi and Regeneron. Dupilumab is a blockbuster drug that targets the same IL-4Rα pathway and is already approved and widely prescribed for these exact conditions, having established a dominant market position years prior to CBP-201's current stage of development. This established market leader poses a substantial hurdle for CBP-201's future commercial viability, requiring significant differentiation in efficacy, safety, or cost to compete effectively.

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Connect Biopharma (CNTB) Addressable Markets

Connect Biopharma's main products target several significant addressable markets globally and in the U.S.:

  • CBP-201 (anti-interleukin-4 receptor alpha antibody) is in Phase IIb clinical trial for the treatment of inflammatory allergic diseases, including atopic dermatitis, asthma, and chronic rhinosinusitis with nasal polyps:
    • For **Atopic Dermatitis**: The global atopic dermatitis drugs market was estimated at approximately USD 12.1 billion in 2024 and is projected to reach USD 31 billion by 2034. The U.S. atopic dermatitis drugs market generated USD 4.7 billion in 2023 and is expected to reach USD 13.1 billion by 2034. Other sources suggest the global market was USD 15.92 billion in 2025, projected to reach USD 33.42 billion by 2035.
    • For **Asthma**: The global asthma market size was around USD 27 billion in 2024 and is expected to grow through 2025–2034. The U.S. asthma market was valued at approximately USD 21.5 billion in 2024. Another report states the U.S. asthma drugs market size was valued at USD 10.45 billion in 2025 and is projected to surpass approximately USD 17.25 billion by 2035.
    • For **Chronic Rhinosinusitis with Nasal Polyps**: The global market size for chronic rhinosinusitis with nasal polyps is projected to grow from USD 5.1 billion in 2024 to USD 7.6 billion by 2030. The U.S. market is estimated at USD 1.91 billion in 2024 and is projected to reach approximately USD 2.66 billion by 2030.
  • CBP-307 (small molecule modulator of sphingosine 1-phosphate receptor 1) is in Phase II for the treatment of autoimmune-related inflammation diseases:
    • For **Autoimmune Diseases**: The global autoimmune disease therapeutics market is valued at USD 168.6 billion in 2025 and is forecast to reach USD 226.2 billion by 2035. The U.S. autoimmune disease therapeutics market is estimated at USD 32.18 billion in 2025 and is expected to reach USD 49.12 billion by 2033.
  • CBP-174 (small molecule histamine receptor 3 antagonist) is in a preclinical stage to treat chronic itch associated with skin inflammation:
    • For **Chronic Itch (Pruritus)**: The global chronic pruritus therapeutics market size accounted for USD 11.25 billion in 2024 and is projected to surpass approximately USD 17.26 billion by 2034. The chronic pruritus market in the 7MM (United States, EU4, UK, and Japan) was valued at approximately USD 3,845 million in 2025 and is projected to reach an estimated USD 8,110 million by 2034. The U.S. pruritus therapeutics market size was exhibited at USD 3.23 billion in 2024 and is projected to be worth around USD 4.99 billion by 2034.
  • CBP-233 (humanized antibody against interleukin-33) is a preclinical stage humanized antibody against interleukin-33, a cytokine involved in T helper 2 inflammation:
    • The addressable market for CBP-233, which targets IL-33 involved in T helper 2 (Th2) inflammation, would primarily overlap with inflammatory allergic diseases such as atopic dermatitis and asthma. Market sizes for these conditions are provided above.

AI Analysis | Feedback

Connect Biopharma (CNTB) is expected to drive future revenue growth over the next 2-3 years through several key initiatives focused on the advancement and commercialization of its lead product candidates and strategic partnerships:

  1. Commercialization of Rademikibart (CBP-201) for Atopic Dermatitis in China: Connect Biopharma anticipates potential marketing approval for rademikibart in China for moderate-to-severe atopic dermatitis as early as 2025, following positive pivotal trial data and ongoing engagement with China's Center for Drug Evaluation (CDE). The company has granted Simcere Pharmaceutical Co., Ltd. exclusive rights to develop, manufacture, and commercialize rademikibart in Greater China, with an analyst projection of $120 million in annual sales as early as 2026 for the China AD market.
  2. Milestone Payments and Royalties from Simcere Partnership: The existing license and collaboration agreement with Simcere Pharmaceutical Co., Ltd. for rademikibart in Greater China is already generating revenue through upfront fees, development milestones, and cost reimbursements. Continued progress in China, including regulatory approvals and sales, is expected to lead to further milestone payments and eventual royalties within the next 2-3 years.
  3. New Strategic Partnerships and Out-licensing Agreements: Connect Biopharma is actively seeking partnerships, particularly to advance the global Phase 3 program for rademikibart in moderate-to-severe atopic dermatitis, which was paused due to the funding environment until a suitable partner is secured. Additionally, the company is looking to out-license CBP-307 for future trials in ulcerative colitis and Crohn's disease. Successful execution of these partnerships within the timeframe could generate significant upfront payments and future milestone revenues.
  4. Advancement of Rademikibart (CBP-201) for Asthma and COPD: Following positive Phase 2b data for rademikibart in moderate-to-severe persistent asthma, Connect Biopharma has outlined a rapid clinical development strategy targeting acute asthma and COPD exacerbations. Parallel Phase 2 trials are expected to initiate in the second quarter of 2025, with top-line data anticipated in the second half of 2026. Positive results could pave the way for further development, potential partnerships, and eventual commercialization, contributing to revenue growth.

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Share Issuance

  • In March 2021, Connect Biopharma completed its initial public offering (IPO) on the Nasdaq Global Market, raising $191 million by pricing an upsized US IPO at $17 per share.
  • The company's shares outstanding were 56 million in Q3 2025, reflecting a 0.3% increase from the prior quarter.

Inbound Investments

  • Connect Biopharma is eligible to receive remaining milestone payments of up to approximately $110 million from an exclusive license and collaboration agreement with Simcere Pharmaceutical Co., Ltd. for rademikibart in Greater China.
  • Simcere Pharmaceutical paid Connect Biopharma approximately $24 million in upfront and regulatory milestones for the rights to develop and commercialize rademikibart in China.

Capital Expenditures

  • Connect Biopharma Holdings Ltd invested $34K in capital expenditures in Q3 2025.
  • Capital expenditures of $750K contributed to the company's free cash flow of -$24.4M in a period where it generated -$23.6M in operating cash flow.

Trade Ideas

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ABT_4302026_Dip_Buyer_ValueBuy04302026ABTAbbott LaboratoriesDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
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ZBIO_4302026_Insider_Buying_45D_2Buy_200K04302026ZBIOZenas BioPharmaInsiderInsider Buys 45DStrong Insider Buying
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Recent Active Movers

Peer Comparisons

Peers to compare with:

Financials

CNTBREGNAMGNLLYABBVINCYMedian
NameConnect .Regenero.Amgen Eli LillyAbbVie Incyte  
Mkt Price2.49614.78336.791,105.00217.7296.74277.25
Mkt Cap0.163.9181.9988.4385.419.3122.9
Rev LTM014,92037,22072,25062,8195,36126,070
Op Inc LTM-663,84310,56834,17220,8441,4507,205
FCF LTM-583,7918,59710,36819,9801,4216,194
FCF 3Y Avg-3,5618,8701,73419,0858333,561
CFO LTM-575,01310,75620,48021,2241,5177,884
CFO 3Y Avg-4,56810,34811,15820,10490710,348

Growth & Margins

CNTBREGNAMGNLLYABBVINCYMedian
NameConnect .Regenero.Amgen Eli LillyAbbVie Incyte  
Rev Chg LTM-99.1%5.9%9.1%47.4%9.5%21.5%9.3%
Rev Chg 3Y Avg-6.4%12.5%37.9%3.6%15.7%12.5%
Rev Chg Q-19.0%5.8%55.5%12.4%20.9%19.0%
QoQ Delta Rev Chg LTM264.1%4.0%1.3%10.8%2.7%4.3%4.1%
Op Inc Chg LTM-211.5%-2.4%41.9%73.3%61.4%540.1%51.7%
Op Inc Chg 3Y Avg--6.3%8.8%67.4%12.1%171.7%12.1%
Op Mgn LTM-28,426.6%25.8%28.4%47.3%33.2%27.1%27.7%
Op Mgn 3Y Avg-28.1%24.6%39.7%26.9%17.1%26.9%
QoQ Delta Op Mgn LTM62,314.0%-0.1%3.7%1.7%0.3%0.9%1.3%
CFO/Rev LTM-24,571.7%33.6%28.9%28.3%33.8%28.3%28.6%
CFO/Rev 3Y Avg-32.6%30.7%19.2%34.7%19.6%30.7%
FCF/Rev LTM-24,723.2%25.4%23.1%14.4%31.8%26.5%24.3%
FCF/Rev 3Y Avg-25.5%26.4%0.3%33.0%18.0%25.5%

Valuation

CNTBREGNAMGNLLYABBVINCYMedian
NameConnect .Regenero.Amgen Eli LillyAbbVie Incyte  
Mkt Cap0.163.9181.9988.4385.419.3122.9
P/S604.34.34.913.76.13.65.5
P/Op Inc-2.116.617.228.918.513.316.9
P/EBIT-2.112.315.427.643.410.913.9
P/E-2.214.523.339.1106.013.518.9
P/CFO-2.512.816.948.318.212.714.8
Total Yield-45.9%7.5%7.1%3.1%4.0%7.4%5.6%
Dividend Yield0.0%0.6%2.9%0.6%3.1%0.0%0.6%
FCF Yield 3Y Avg-4.3%5.2%0.2%5.4%5.4%5.2%
D/E0.00.00.30.00.20.00.0
Net D/E-0.3-0.10.20.00.2-0.2-0.0

Returns

CNTBREGNAMGNLLYABBVINCYMedian
NameConnect .Regenero.Amgen Eli LillyAbbVie Incyte  
1M Rtn0.8%-12.2%2.9%14.9%5.4%-0.2%1.8%
3M Rtn0.8%-21.2%-12.6%5.2%-5.4%-4.5%-4.9%
6M Rtn-11.4%-21.0%-1.1%3.1%-2.8%-7.4%-5.1%
12M Rtn196.4%26.1%20.4%50.9%20.8%48.7%37.4%
3Y Rtn124.3%-15.2%72.3%158.6%81.7%57.3%77.0%
1M Excs Rtn-7.8%-16.5%-5.8%23.8%0.6%-8.6%-6.8%
3M Excs Rtn-9.4%-31.4%-22.8%-5.0%-15.6%-14.7%-15.1%
6M Excs Rtn-22.5%-33.7%-11.9%-12.1%-16.6%-20.4%-18.5%
12M Excs Rtn190.5%-24.3%-4.1%26.0%-5.9%20.3%8.1%
3Y Excs Rtn30.0%-100.0%-18.3%83.9%-12.7%-34.2%-15.5%

Comparison Analyses

null

Financials

Segment Financials

Revenue by Segment
$ Mil20252024202320222021
Treatment of respiratory diseases26    
Total26    


Net Income by Segment
$ Mil20252024202320222021
Treatment of respiratory diseases-16    
Total-16    


Assets by Segment
$ Mil20252024202320222021
Single Segment 126176291166
Total 126176291166


Price Behavior

Price Behavior
Market Price$2.49 
Market Cap ($ Bil)0.1 
First Trading Date03/19/2021 
Distance from 52W High-32.5% 
   50 Days200 Days
DMA Price$2.66$2.30
DMA Trendupdown
Distance from DMA-6.3%8.1%
 3M1YR
Volatility86.6%105.6%
Downside Capture130.97-54.72
Upside Capture85.3992.21
Correlation (SPY)4.2%-2.1%
CNTB Betas & Captures as of 5/31/2026

 1M2M3M6M1Y3Y
Beta1.970.340.230.59-0.210.52
Up Beta0.96-2.15-2.85-1.25-1.530.15
Down Beta8.098.382.280.400.330.81
Up Capture69%31%84%109%79%50%
Bmk +ve Days13283667141432
Stock +ve Days9183260120337
Down Capture167%246%128%160%-101%82%
Bmk -ve Days7132757109318
Stock -ve Days8192759117378

[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with CNTB
CNTB203.8%105.3%1.53-
Sector ETF (XLV)15.8%14.6%0.78-0.7%
Equity (SPY)30.3%11.8%1.94-2.1%
Gold (GLD)37.5%26.7%1.176.0%
Commodities (DBC)39.6%18.8%1.638.3%
Real Estate (VNQ)12.5%13.1%0.64-6.8%
Bitcoin (BTCUSD)-32.0%41.6%-0.82-3.5%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 5-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with CNTB
CNTB-31.4%113.9%0.23-
Sector ETF (XLV)5.4%14.7%0.198.0%
Equity (SPY)14.3%17.0%0.669.3%
Gold (GLD)18.8%18.0%0.851.1%
Commodities (DBC)10.2%19.4%0.411.6%
Real Estate (VNQ)3.4%18.8%0.087.0%
Bitcoin (BTCUSD)14.5%54.6%0.464.2%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 10-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with CNTB
CNTB-18.6%112.6%0.20-
Sector ETF (XLV)9.9%16.5%0.498.2%
Equity (SPY)15.9%17.9%0.769.2%
Gold (GLD)13.3%16.0%0.691.1%
Commodities (DBC)7.3%17.9%0.331.5%
Real Estate (VNQ)5.7%20.7%0.246.6%
Bitcoin (BTCUSD)66.9%66.9%1.064.5%

Smart multi-asset allocation framework can stack odds in your favor. Learn How

Short Interest

Short Interest: As Of Date5152026
Short Interest: Shares Quantity1.2 Mil
Short Interest: % Change Since 43020262.1%
Average Daily Volume0.1 Mil
Days-to-Cover Short Interest8.2 days
Basic Shares Quantity56.5 Mil
Short % of Basic Shares2.0%

Earnings Returns History

Updated N/A/N/A/N/A
Expand for More
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
5/12/202614.5%1.7% 
11/12/20255.9%69.1%64.5%
8/13/20254.0%-20.3%-28.2%
5/15/2025-5.6%5.8%23.4%
SUMMARY STATS   
# Positive332
# Negative111
Median Positive5.9%5.8%43.9%
Median Negative-5.6%-20.3%-28.2%
Max Positive14.5%69.1%64.5%
Max Negative-5.6%-20.3%-28.2%

SEC Filings

Expand for More
Report DateFiling DateFiling
03/31/202605/12/202610-Q
12/31/202503/31/202610-K
09/30/202511/12/202510-Q
06/30/202508/13/202510-Q
03/31/202505/15/202510-Q
12/31/202403/31/202510-K
06/30/202409/05/20246-K
12/31/202304/16/202420-F
06/30/202309/12/20236-K
12/31/202204/11/202320-F
06/30/202209/13/20226-K
12/31/202103/31/202220-F
06/30/202108/31/20216-K
12/31/202003/19/2021424B4

Recent Forward Guidance

Updated 5/31/2026

Latest: Q1 2026 Earnings Reported 5/12/2026

Forward GuidanceGuidance Change
MetricLowMidHigh% Chg% DeltaChangePrior
2027 Cash Runway      

Prior: Q3 2025 Earnings Reported 11/12/2025

Forward GuidanceGuidance Change
MetricLowMidHigh% Chg% DeltaChangePrior
2027 Cash Runway      

Insider Activity

Updated 4/26/2026
Expand for More
#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Huang, James See FootnoteBuy40120263.451,160,0004,002,00045,402,000Form
Core Cache Last Updated: 5/31/2026