Tearsheet

Cidara Therapeutics (CDTX)


Market Price (12/5/2025): $220.35 | Market Cap: $5.9 Bil
Sector: Health Care | Industry: Biotechnology

Cidara Therapeutics (CDTX)


Market Price (12/5/2025): $220.35
Market Cap: $5.9 Bil
Sector: Health Care
Industry: Biotechnology

Investment Highlights Why It Matters Which of these 2 stories sounds closer for this stock?

1. Generates cash flow

The stock generated 4% or more of the share price (called cash flow yield), and shows moderate 10-15% or more growth.

2. Riding a trend

Think Tesla during the pandemic of 2020 when EVs were riding a cultural high, or Nvidia in the current AI boom, or even Figma. These companies don’t have enough yield, or, enough growth, or both - however - they are riding a trend. They have momentum. These can be more volatile - they don’t have the floor of strong cash flow


0 Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -16%
Trading close to highs
Dist 52W High is -0.2%, Dist 3Y High is -0.2%
Very low revenue
Rev LTMTotal Revenue or Sales, Last Twelve Months is 0
1 Megatrend and thematic drivers
Megatrends include Precision Medicine. Themes include Novel Anti-Infective Development, and Targeted Therapies.
Meaningful short interest
Short Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 12%
Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -195 Mil
2   Stock price has recently run up significantly
6M Rtn6 month market price return is 817%, 12M Rtn12 month market price return is 1005%
3   Weak revenue growth
Rev Chg LTMRevenue Change % Last Twelve Months (LTM) is null, Rev Chg 3Y AvgRevenue Change % averaged over trailing 3 years is -70%
4   Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -11%
5   High stock price volatility
Vol 12M is 171%
0 Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -16%
1 Megatrend and thematic drivers
Megatrends include Precision Medicine. Themes include Novel Anti-Infective Development, and Targeted Therapies.
2 Trading close to highs
Dist 52W High is -0.2%, Dist 3Y High is -0.2%
3 Meaningful short interest
Short Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 12%
4 Very low revenue
Rev LTMTotal Revenue or Sales, Last Twelve Months is 0
5 Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -195 Mil
6 Stock price has recently run up significantly
6M Rtn6 month market price return is 817%, 12M Rtn12 month market price return is 1005%
7 Weak revenue growth
Rev Chg LTMRevenue Change % Last Twelve Months (LTM) is null, Rev Chg 3Y AvgRevenue Change % averaged over trailing 3 years is -70%
8 Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -11%
9 High stock price volatility
Vol 12M is 171%

Valuation, Metrics & Events

CDTX Stock


Why The Stock Moved


Qualitative Assessment

AI Generated Analysis | Feedback

1. Merck Acquisition Announcement. On November 14, 2025, Merck announced its intention to acquire Cidara Therapeutics for $221.50 per share, valuing the transaction at approximately $9.2 billion. This acquisition, which focused on Cidara's lead candidate CD388, served as a primary driver for the significant increase in the stock price.

2. FDA Breakthrough Therapy Designation for CD388. On October 9, 2025, Cidara Therapeutics announced that the U.S. Food and Drug Administration (FDA) granted Breakthrough Therapy designation for CD388. This designation was for the prevention of influenza A and B in certain high-risk adults and adolescents, and it is expected to expedite the development and regulatory review process for the therapeutic.

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Stock Movement Drivers

Return vs. Risk


Price Returns Compared

 202020212022202320242025Total [1]
Returns
CDTX Return-48%-36%-40%5%69%720%187%
Peers Return2%-1%6%8%-0%3%18%
S&P 500 Return16%27%-19%24%23%17%112%

Monthly Win Rates [3]
CDTX Win Rate25%25%42%42%58%70% 
Peers Win Rate13%8%13%12%10%90% 
S&P 500 Win Rate58%75%42%67%75%70% 

Max Drawdowns [4]
CDTX Max Drawdown-55%-41%-66%-10%-36%-39% 
Peers Max Drawdown-2%-5%0%-0%-1%-2% 
S&P 500 Max Drawdown-31%-1%-25%-1%-2%-15% 


[1] Cumulative total returns since the beginning of 2020
[2] Peers: VRTX, AIXC, ALPS, BBOT, EVMN.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2025 data is for the year up to 12/4/2025 (YTD)

How Low Can It Go

Unique KeyEventCDTXS&P 500
2022 Inflation Shock2022 Inflation Shock  
2022 Inflation Shock% Loss% Loss-85.8%-25.4%
2022 Inflation Shock% Gain to Breakeven% Gain to Breakeven603.3%34.1%
2022 Inflation ShockTime to BreakevenTime to Breakeven1166 days464 days
2020 Covid Pandemic2020 Covid Pandemic  
2020 Covid Pandemic% Loss% Loss-59.2%-33.9%
2020 Covid Pandemic% Gain to Breakeven% Gain to Breakeven144.8%51.3%
2020 Covid PandemicTime to BreakevenTime to Breakeven2018 days148 days
2018 Correction2018 Correction  
2018 Correction% Loss% Loss-89.3%-19.8%
2018 Correction% Gain to Breakeven% Gain to Breakeven836.0%24.7%
2018 CorrectionTime to BreakevenTime to BreakevenNot Fully Recovered days120 days

Compare to VRTX, AIXC, ALPS, BBOT, EVMN


In The Past

Cidara Therapeutics's stock fell -85.8% during the 2022 Inflation Shock from a high on 2/17/2021. A -85.8% loss requires a 603.3% gain to breakeven.

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About Cidara Therapeutics (CDTX)

Better Bets than Cidara Therapeutics (CDTX)

Latest Trefis Analyses

Title
0ARTICLES

Trade Ideas

Select past ideas related to CDTX. For more, see Trefis Trade Ideas.

Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
CRL_11142025_Dip_Buyer_FCFYield11142025CRLCharles River Laboratories InternationalDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
10.0%10.0%-3.7%
GDRX_11142025_Dip_Buyer_High_CFO_Margins_ExInd_DE11142025GDRXGoodRxDip BuyDB | CFO/Rev | Low D/EDip Buy with High Cash Flow Margins
Buying dips for companies with significant cash flows from operations and reasonable debt / market cap
-7.7%-7.7%-11.8%
ASTH_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025ASTHAstrana HealthDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
6.9%6.9%-5.5%
SGRY_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025SGRYSurgery PartnersDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
11.5%11.5%-1.4%
TFX_11072025_Dip_Buyer_FCFYield11072025TFXTeleflexDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
8.9%8.9%-5.1%
Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
CRL_11142025_Dip_Buyer_FCFYield11142025CRLCharles River Laboratories InternationalDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
10.0%10.0%-3.7%
GDRX_11142025_Dip_Buyer_High_CFO_Margins_ExInd_DE11142025GDRXGoodRxDip BuyDB | CFO/Rev | Low D/EDip Buy with High Cash Flow Margins
Buying dips for companies with significant cash flows from operations and reasonable debt / market cap
-7.7%-7.7%-11.8%
ASTH_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025ASTHAstrana HealthDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
6.9%6.9%-5.5%
SGRY_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025SGRYSurgery PartnersDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
11.5%11.5%-1.4%
TFX_11072025_Dip_Buyer_FCFYield11072025TFXTeleflexDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
8.9%8.9%-5.1%

Recent Active Movers

Recent Active Movers

More From Trefis

Peer Comparisons for Cidara Therapeutics

Peers to compare with:

Financials

CDTXVRTXAIXCALPSBBOTEVMNMedian
NameCidara T.Vertex P.AIxCryptoALPS BridgeBi.Evommune  
Mkt Price220.50457.362.631.1711.5421.9316.73
Mkt Cap5.9116.9----61.4
Rev LTM011,7230-0100
Op Inc LTM-195-92-5--93-70-92
FCF LTM-1333,337-6--60-64-60
FCF 3Y Avg-1082,064-10----10
CFO LTM-1333,718-6--60-64-60
CFO 3Y Avg-1082,419-10----10

Growth & Margins

CDTXVRTXAIXCALPSBBOTEVMNMedian
NameCidara T.Vertex P.AIxCryptoALPS BridgeBi.Evommune  
Rev Chg LTM-100.0%10.3%-----44.8%
Rev Chg 3Y Avg-69.7%10.5%-----29.6%
Rev Chg Q-11.0%----11.0%
QoQ Delta Rev Chg LTM-2.7%----2.7%
Op Mgn LTM--0.8%----700.7%-350.7%
Op Mgn 3Y Avg-26.2%----26.2%
QoQ Delta Op Mgn LTM-1.0%----1.0%
CFO/Rev LTM-31.7%----635.6%-302.0%
CFO/Rev 3Y Avg-23.1%----23.1%
FCF/Rev LTM-28.5%----636.5%-304.0%
FCF/Rev 3Y Avg-19.8%----19.8%

Valuation

CDTXVRTXAIXCALPSBBOTEVMNMedian
NameCidara T.Vertex P.AIxCryptoALPS BridgeBi.Evommune  
Mkt Cap5.9116.9----61.4
P/S-8.5----8.5
P/EBIT-13.222.4----4.6
P/E-13.927.2----6.7
P/CFO-19.426.9----3.8
Total Yield-7.2%3.7%-----1.8%
Dividend Yield0.0%0.0%----0.0%
FCF Yield 3Y Avg-89.9%2.3%-----43.8%
D/E0.00.0----0.0
Net D/E-0.2-0.0-----0.1

Returns

CDTXVRTXAIXCALPSBBOTEVMNMedian
NameCidara T.Vertex P.AIxCryptoALPS BridgeBi.Evommune  
1M Rtn119.6%8.5%-23.2%-4.6%-15.8%
3M Rtn239.6%15.2%--14.5%-15.2%
6M Rtn816.8%3.1%----409.9%
12M Rtn1,005.3%-1.4%----501.9%
3Y Rtn1,737.5%44.0%----890.8%
1M Excs Rtn118.4%7.2%-22.0%-5.9%-14.6%
3M Excs Rtn243.3%9.7%--10.8%-10.8%
6M Excs Rtn801.4%-12.4%----394.5%
12M Excs Rtn1,062.0%-15.2%----523.4%
3Y Excs Rtn1,455.2%-28.7%----713.3%

Financials

Segment Financials

Revenue by Segment

$ Mil20242023202220212020
Single Segment 64501221
Total 64501221


Assets by Segment
$ Mil20242023202220212020
Single Segment67    
Total67    


Price Behavior

Short Interest

Short Interest: As Of Date11142025
Short Interest: Shares Quantity3,297,917
Short Interest: % Change Since 103120253.0%
Average Daily Volume2,222,352
Days-to-Cover Short Interest1.48
Basic Shares Quantity26,882,366
Short % of Basic Shares12.3%

SEC Filings

Expand for More

Report DateFiling DateFiling
93020251106202510-Q 9/30/2025
6302025807202510-Q 6/30/2025
3312025508202510-Q 3/31/2025
12312024306202510-K 12/31/2024
93020241107202410-Q 9/30/2024
6302024813202410-Q 6/30/2024
3312024515202410-Q 3/31/2024
12312023422202410-K 12/31/2023
93020231102202310-Q 9/30/2023
6302023803202310-Q 6/30/2023
3312023511202310-Q 3/31/2023
12312022323202310-K 12/31/2022
93020221103202210-Q 9/30/2022
6302022809202210-Q 6/30/2022
3312022511202210-Q 3/31/2022
12312021307202210-K 12/31/2021

Insider Activity

Expand for More

 OwnerTitleFiling DateActionPriceSharesTransacted
Value
Value of
Held Shares
Form
0Davarpanah Nicole NegarChief Medical Officer9152025Sell62.8647429,7971,975,020Form
1RA CAPITAL MANAGEMENT, L.P.6302025Buy44.002,272,72799,999,988148,083,012Form
2Mineo Chrysa 6042025Buy21.712,27049,28149,281Form
3Ward ShaneCOO & CLO3132025Sell21.961,66436,542322,247Form
4Tari LeslieCHIEF SCIENTIFIC OFFICER3132025Sell21.961,77338,940356,124Form