Matinas BioPharma (MTNB)


Market Price (9/14/2026): $0.1856 | Market Cap: $1.2 MilSector: Health Care | Industry: Biotechnology

Matinas BioPharma (MTNB)


Market Price (9/14/2026): $0.1856
Market Cap: $1.2 Mil
Sector: Health Care
Industry: Biotechnology

Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.

0

Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -65%

Megatrend and thematic drivers
Megatrends include Precision Medicine. Themes include Biopharmaceutical R&D, and Targeted Therapies.

Weak multi-year price returns
2Y Excs Rtn is -136%, 3Y Excs Rtn is -169%

Penny stock
Mkt Price is 0.2

Very low revenue
Rev LTMTotal Revenue or Sales, Last Twelve Months is 0

Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -6.7 Mil

Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -584%

High stock price volatility
Vol 12M is 115%

Key risks
MTNB key risks include [1] its questionable viability as a going concern due to a critical cash shortage and halted lead drug development, Show more.

0 Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -65%
1 Megatrend and thematic drivers
Megatrends include Precision Medicine. Themes include Biopharmaceutical R&D, and Targeted Therapies.
2 Weak multi-year price returns
2Y Excs Rtn is -136%, 3Y Excs Rtn is -169%
3 Penny stock
Mkt Price is 0.2
4 Very low revenue
Rev LTMTotal Revenue or Sales, Last Twelve Months is 0
5 Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -6.7 Mil
6 Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -584%
7 High stock price volatility
Vol 12M is 115%
8 Key risks
MTNB key risks include [1] its questionable viability as a going concern due to a critical cash shortage and halted lead drug development, Show more.

Valuation & Metrics

Price Chart

Why The Stock Moved

Qualitative Assessment

AI Analysis | Feedback

Updated on 9/1/2026

Matinas BioPharma (MTNB) stock has lost about 75% since 5/31/2026 because of the following key factors:

1. Substantial Doubt Regarding Ability to Continue as a Going Concern and Significant Financial Distress. Matinas BioPharma reported a net loss of $1.33 million for its fiscal Q2 2026, which ended on June 30, 2026, and a net loss of $3.25 million for the first half of fiscal year 2026. As of June 30, 2026, the company held only $761 thousand in cash and cash equivalents, with total stockholders' equity at $1.80 million. Matinas BioPharma explicitly stated that its existing cash was insufficient to fund operations for 12 months, concluding that "substantial doubt exists about its ability to continue as a going concern." This critical financial instability was further underscored by a "very high" financial-distress risk score of 85 out of 100 during the period from May 30, 2026, through August 27, 2026.

2. Non-Compliance with NYSE American Listing Standards. On June 26, 2026, Matinas BioPharma disclosed receipt of a notice from NYSE American indicating non-compliance with continued listing standards. Specifically, the company failed to meet the requirement of having at least $4.0 million in stockholders' equity (reporting $3.02 million as of March 31, 2026) for companies with losses in three of their four most recent fiscal years, and $6.0 million in stockholders' equity (reporting $4.83 million as of December 31, 2025) for those with losses in their five most recent fiscal years. Although a plan to regain compliance was accepted, this notice highlighted severe financial distress and posed a significant delisting risk, negatively impacting investor confidence.

Show more
Updated on 9/1/2026

Matinas BioPharma (MTNB) stock has lost about 75% since 5/31/2026 because of the following key factors:

1. Substantial Doubt Regarding Ability to Continue as a Going Concern and Significant Financial Distress. Matinas BioPharma reported a net loss of $1.33 million for its fiscal Q2 2026, which ended on June 30, 2026, and a net loss of $3.25 million for the first half of fiscal year 2026. As of June 30, 2026, the company held only $761 thousand in cash and cash equivalents, with total stockholders' equity at $1.80 million. Matinas BioPharma explicitly stated that its existing cash was insufficient to fund operations for 12 months, concluding that "substantial doubt exists about its ability to continue as a going concern." This critical financial instability was further underscored by a "very high" financial-distress risk score of 85 out of 100 during the period from May 30, 2026, through August 27, 2026.

2. Non-Compliance with NYSE American Listing Standards. On June 26, 2026, Matinas BioPharma disclosed receipt of a notice from NYSE American indicating non-compliance with continued listing standards. Specifically, the company failed to meet the requirement of having at least $4.0 million in stockholders' equity (reporting $3.02 million as of March 31, 2026) for companies with losses in three of their four most recent fiscal years, and $6.0 million in stockholders' equity (reporting $4.83 million as of December 31, 2025) for those with losses in their five most recent fiscal years. Although a plan to regain compliance was accepted, this notice highlighted severe financial distress and posed a significant delisting risk, negatively impacting investor confidence.

3. Strategic Shift from Biopharmaceuticals and Divestiture of Core Assets. Matinas BioPharma announced on July 13, 2026, a strategic business combination with GH Power Inc., an advanced clean energy and green hydrogen company. This agreement fundamentally shifts the company's business focus away from biopharmaceutical development. Concurrently, Matinas signed a definitive agreement to sell its core Lipid NanoCrystal (LNC) platform technology and its lead product candidate, MAT2203, to Azurity Pharmaceuticals for a potential total consideration of up to $21.5 million plus royalties. This move effectively liquidates the company's prior pharmaceutical development pipeline and represents a significant dilution for existing shareholders, as GH Power shareholders are expected to own approximately 91% of the combined entity following the merger.

4. Cessation of Research and Development Spending. The company's fiscal Q2 2026 earnings report revealed that operating expenses of $1.56 million were "driven entirely by general and administrative costs, with no research and development spending reported." This absence of R&D investment is a strong indicator of Matinas BioPharma's abandonment of its biopharmaceutical pipeline and its focus on the new strategic direction, further signaling a lack of future growth prospects in its original sector.

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Stock Movement Drivers

Fundamental Drivers

The -77.2% change in MTNB stock from 5/31/2026 to 9/13/2026 was primarily driven by a 0.0% change in the company's Shares Outstanding (Mil).
(LTM values as of)53120269132026Change
Stock Price ($)0.810.18-77.2%
Change Contribution By: 
Total Revenues ($ Mil)000.0%
P/S Multiple0.0%
Shares Outstanding (Mil)660.0%
Cumulative Contribution0.0%

LTM = Last Twelve Months as of date shown

Market Drivers

5/31/2026 to 9/13/2026
ReturnCorrelation
MTNB-77.2% 
Market (SPY)1.0%5.2%
Sector (XLV)10.6%21.6%

Fundamental Drivers

The -69.6% change in MTNB stock from 2/28/2026 to 9/13/2026 was primarily driven by a -15.1% change in the company's Shares Outstanding (Mil).
(LTM values as of)22820269132026Change
Stock Price ($)0.610.18-69.6%
Change Contribution By: 
Total Revenues ($ Mil)000.0%
P/S Multiple0.0%
Shares Outstanding (Mil)56-15.1%
Cumulative Contribution0.0%

LTM = Last Twelve Months as of date shown

Market Drivers

2/28/2026 to 9/13/2026
ReturnCorrelation
MTNB-69.6% 
Market (SPY)11.7%3.6%
Sector (XLV)3.6%11.7%

Fundamental Drivers

The -89.8% change in MTNB stock from 8/31/2025 to 9/13/2026 was primarily driven by a -20.6% change in the company's Shares Outstanding (Mil).
(LTM values as of)83120259132026Change
Stock Price ($)1.820.18-89.8%
Change Contribution By: 
Total Revenues ($ Mil)000.0%
P/S Multiple0.0%
Shares Outstanding (Mil)56-20.6%
Cumulative Contribution0.0%

LTM = Last Twelve Months as of date shown

Market Drivers

8/31/2025 to 9/13/2026
ReturnCorrelation
MTNB-89.8% 
Market (SPY)19.5%3.7%
Sector (XLV)21.9%5.7%

Fundamental Drivers

The -97.9% change in MTNB stock from 8/31/2023 to 9/13/2026 was primarily driven by a null change in the company's Total Revenues ($ Mil).
(LTM values as of)83120239132026Change
Stock Price ($)9.000.18-97.9%
Change Contribution By: 
Total Revenues ($ Mil)30 
P/S Multiple12.19.2233720368547763E17%
Shares Outstanding (Mil)46-32.2%
Cumulative Contribution0.0%

LTM = Last Twelve Months as of date shown

Market Drivers

8/31/2023 to 9/13/2026
ReturnCorrelation
MTNB-97.9% 
Market (SPY)75.7%5.9%
Sector (XLV)30.0%4.2%

Return vs. Risk

Price Returns Compared

 202120222023202420252026Total [1]
Returns
MTNB Return-26%-50%-57%-95%15%-65%-100%
Peers Return25%-9%-9%-15%93%65%180%
S&P 500 Return27%-19%24%23%16%11%102%

Monthly Win Rates [3]
MTNB Win Rate33%42%33%25%50%56% 
Peers Win Rate50%50%38%37%65%49% 
S&P 500 Win Rate75%42%67%75%67%44% 

Max Drawdowns [4]
MTNB Max Drawdown-61%-56%-83%-97%-75%-79% 
Peers Max Drawdown-45%-45%-43%-46%-35%-35% 
S&P 500 Max Drawdown-5%-25%-10%-8%-19%-9% 


[1] Cumulative total returns since the beginning of 2021
[2] Peers: ARWR, ALNY, IONS, ABUS, MRNA.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 9/11/2026 (YTD)

How Low Can It Go

EventMTNBS&P 500
2025 US Tariff Shock
  % Loss-10.2%-18.8%
  % Gain to Breakeven11.3%23.1%
  Time to Breakeven4 days79 days
Summer-Fall 2023 Five Percent Yield Shock
  % Loss-69.3%-9.5%
  % Gain to Breakeven226.3%10.5%
  Time to Breakeven8 days24 days
2023 SVB Regional Banking Crisis
  % Loss-33.9%-6.7%
  % Gain to Breakeven51.3%7.1%
  Time to Breakeven96 days31 days
2020 COVID-19 Crash
  % Loss-59.6%-33.7%
  % Gain to Breakeven147.6%50.9%
  Time to Breakeven268 days140 days
Q4 2018 Fed Policy Error / Growth Scare
  % Loss-47.7%-19.2%
  % Gain to Breakeven91.3%23.8%
  Time to Breakeven21 days105 days

Compare to ARWR, ALNY, IONS, ABUS, MRNA

In The Past

Matinas BioPharma's stock fell -10.2% during the 2025 US Tariff Shock. Such a loss loss requires a 11.3% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

EventMTNBS&P 500
Summer-Fall 2023 Five Percent Yield Shock
  % Loss-69.3%-9.5%
  % Gain to Breakeven226.3%10.5%
  Time to Breakeven8 days24 days
2023 SVB Regional Banking Crisis
  % Loss-33.9%-6.7%
  % Gain to Breakeven51.3%7.1%
  Time to Breakeven96 days31 days
2020 COVID-19 Crash
  % Loss-59.6%-33.7%
  % Gain to Breakeven147.6%50.9%
  Time to Breakeven268 days140 days
Q4 2018 Fed Policy Error / Growth Scare
  % Loss-47.7%-19.2%
  % Gain to Breakeven91.3%23.8%
  Time to Breakeven21 days105 days

Compare to ARWR, ALNY, IONS, ABUS, MRNA

In The Past

Matinas BioPharma's stock fell -10.2% during the 2025 US Tariff Shock. Such a loss loss requires a 11.3% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

About Matinas BioPharma (MTNB)

Matinas BioPharma Holdings, Inc. (MTNB) is a clinical-stage biopharmaceutical company focused on developing novel therapeutic candidates through its proprietary Lipid Nanocrystal (LNC) platform technology. This innovative platform is designed to improve the delivery and efficacy of a wide range of molecules, including small drugs, nucleic acids, and even gene therapies, potentially making difficult-to-deliver treatments more effective or available in convenient oral formulations. The company leverages this technology to address significant unmet medical needs across various therapeutic areas, with potential applications ranging from infectious diseases to cardiovascular conditions.

The company's pipeline includes several key product candidates. Its lead product, LYPDISO, is an omega-3 free fatty acid-based composition aimed at treating cardiovascular and metabolic conditions. Matinas also develops MAT2203, an oral formulation of amphotericin B currently in Phase II trials for preventing invasive fungal infections in immunosuppressed patients, and MAT2501, an oral amikacin formulation that has completed Phase I for various multidrug-resistant bacterial infections, including non-tuberculous mycobacterium. Additionally, the versatility of its LNC platform is demonstrated through research collaborations, such as one with the National Institute of Allergy and Infectious Diseases for Gilead's antiviral remdesivir, and a feasibility collaboration with Genentech for developing oral formulations. These products target specific patient populations in need of improved, often oral, treatment options for serious diseases.

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Matinas BioPharma (MTNB) is like "Dyson for drug delivery," innovating with its unique lipid nanocrystal (LNC) platform to make medicines safer, more effective, and often turning IV treatments into convenient oral pills. It's also like "Carvana for challenging IV drugs," taking complex, difficult-to-administer intravenous medications and transforming them into simpler, patient-friendly oral versions using their advanced LNC platform.

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  • LYPDISO: A prescription-only omega-3 free fatty acid-based composition for treating cardiovascular and metabolic conditions.
  • MAT2203: An oral formulation of amphotericin B in Phase II clinical trials for preventing invasive fungal infections.
  • MAT2501: An orally administered formulation of the broad-spectrum antibiotic amikacin for treating various multidrug-resistant bacterial infections.
  • LNC Platform Technology: A lipid nanocrystal delivery technology used for the development and delivery of various therapeutic molecules.

AI Analysis | Feedback

As a clinical-stage biopharmaceutical company, Matinas BioPharma (MTNB) is focused on the research and development of product candidates that are currently in various phases of clinical trials (Phase I, Phase II). At this stage, the company does not have commercially approved products available for sale and therefore does not have major commercial customers in the traditional sense (either other companies like distributors or pharmacies, or individual end-users).

Their business model currently involves advancing their pipeline and engaging in research collaborations. The company has a research collaboration with the National Institute of Allergy and Infectious Diseases and a feasibility collaboration with Genentech, Inc. (a subsidiary of Roche Holding AG, symbol: RHHBY). These are development partners rather than customers purchasing finished products.

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Jerome D. Jabbour, Co-founder, Chairman, President, Chief Executive Officer, and Interim Chief Financial Officer

  • Mr. Jabbour is a co-founder of Matinas BioPharma.
  • He has served as CEO since March 2018, Chairman of the Board since March 2025, and President since March 2016. He assumed the duties of interim Chief Financial Officer in January 2026, following the resignation of the previous CFO.
  • His prior roles include Executive Vice President and General Counsel at MediMedia USA, Senior Vice President and Head of Global Legal Affairs for Wockhardt Limited, and senior legal positions at Reliant Pharmaceuticals (a GlaxoSmithKline subsidiary) and Alpharma, Inc.
  • At Reliant Pharmaceuticals, he was directly involved with the in-licensing of Omacor®/Lovaza® and played a key role in its strategic purchase by GlaxoSmithKline for $1.65 billion in 2007.

Theresa Matkovits, Ph.D., Chief Development Officer

  • Dr. Matkovits joined Matinas BioPharma as Chief Development Officer in October 2018.
  • She brings extensive global drug development and commercialization experience from various pharmaceutical and biotech settings.
  • Previously, she served as Chief Operating Officer of ContraVir Pharmaceuticals (now Hepion), where she was instrumental in building out its global development organization and leading antiviral portfolio development.
  • Prior to ContraVir, she was Global Program Leader at NPS Pharmaceuticals, where she led the integration of commercial assets acquired from Takeda and the successful U.S. approval of Natpara.
  • Before NPS, she was Vice President, Innovation Leader at The Medicines Company, where she led the global development and registration of oritavancin (ORBACTIV). Earlier in her career, she held various global leadership positions at Novartis.

Roelof Rongen, Co-founder (former President and Chief Executive Officer)

  • Mr. Rongen co-founded Matinas BioPharma and was integral in progressing it into a public company.
  • He served as President and Chief Executive Officer of Matinas BioPharma until March 2018.
  • He was involved in the development and commercialization of blockbuster products such as Humira® and Lovaza®.
  • Before founding Matinas BioPharma, he was the architect behind Trygg Pharma.
  • He also served as VP for IP and Portfolio Management at Reliant Pharmaceuticals (acquired by GlaxoSmithKline), where he in-licensed Lovaza®. Earlier in his career, he was Global Product Director for Humira® at BASF Pharma (acquired by Abbott/AbbVie).

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The key risks to Matinas BioPharma (MTNB) largely revolve around its immediate financial viability and the significant setbacks in its product development pipeline.

  1. Financial Viability and Going Concern Risk

    Matinas BioPharma is facing severe financial challenges, with its ability to continue as a going concern explicitly in doubt. The company's cash and cash equivalents, as of September 30, 2025, were insufficient to fund operations for the subsequent twelve months, following net losses and negligible revenue. This precarious financial position led the company to implement an 80% workforce reduction and cease all product development activities to conserve cash. Furthermore, Matinas BioPharma received a NYSE American noncompliance notice in January 2025 for failing to hold its annual meeting of stockholders for the fiscal year ending December 31, 2024.
  2. Discontinuation of Lead Product Candidate Development and Loss of Pipeline Progress

    A significant blow to the company's prospects was the termination of negotiations for global rights to MAT2203, its lead product candidate. This has resulted in the discontinuation of MAT2203's development and a halt to all other product development activities, including those related to LYPDISO and MAT2501, to preserve capital. This effectively stalls the company's pipeline, which previously represented its primary source of future value.
  3. Inability to Secure Strategic Alternatives or Partnerships

    With internal product development largely halted, Matinas BioPharma's future hinges on its ability to successfully sell MAT2203 or pursue other strategic alternatives, such as mergers, acquisitions, or in-licensing new assets. There is no assurance that the company will be able to find a suitable partner or execute these transactions on favorable terms, or at all. The evaluation of "other alternatives, including but not limited to winddown and dissolution of the Company" further highlights the critical nature of this risk.

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Matinas BioPharma (MTNB) operates in addressable markets related to its key product candidates, LYPDISO, MAT2203, and MAT2501. The market sizes for these products or services are outlined below, with regional information provided where available.

  • LYPDISO (formerly MAT9001): This prescription-only omega-3 free fatty acid-based composition is intended for the treatment of cardiovascular and metabolic conditions, specifically severe hypertriglyceridemia. The global omega-3 prescription drugs market was valued at approximately USD 1.25 billion in 2023 and is projected to reach around USD 2.77 billion by 2033, demonstrating a compound annual growth rate (CAGR) of 8.29% from 2024 to 2033. Other estimates place the global market size at about USD 1.4 billion in 2023, with an anticipated CAGR of 8.2% from 2024 to 2032, reaching USD 2.8 billion by 2032. Within this market, the cardiovascular diseases segment alone accounted for USD 643.9 million in 2023. North America held a significant share, with the U.S. omega-3 prescription drugs market valued at USD 0.49 billion in 2024 and expected to reach USD 0.82 billion by 2032, growing at a CAGR of 6.74%.

  • MAT2203: An oral formulation of amphotericin B, MAT2203 is being developed for the prevention and treatment of invasive fungal infections, including cryptococcal meningitis and invasive aspergillosis, in immunosuppressed patients. The global invasive fungal infections market was valued at USD 7.55 billion in 2024 and is projected to grow with a CAGR of 3.75% through 2026-2030. Another report indicates the market reached USD 7.4 billion in 2024, with a projected expansion to USD 11.2 billion by 2033, at a CAGR of 4.9% from 2025 to 2033. In 2025, North America was the largest regional market for invasive fungal infections.

  • MAT2501: This orally administered formulation of the broad-spectrum aminoglycoside antibiotic amikacin is being developed to treat various types of multidrug-resistant bacteria, including non-tuberculous mycobacterium (NTM) infections, as well as multidrug-resistant gram-negative and intracellular bacterial infections.

    • Non-tuberculous Mycobacterial (NTM) Infections: The total Nontuberculous Mycobacterial Treatment Market in the U.S. was approximately USD 360 million in 2023 and is projected to increase through 2024–2034. Globally, the Nontuberculous Mycobacterial Infection market size is expected to reach $21.01 billion by 2030, growing at a CAGR of 7.3%. North America was identified as the largest region in the NTM market in 2025.
    • Multidrug-Resistant (MDR) Bacterial Infections (including gram-negative): The global multidrug-resistant bacteria market size was valued at USD 12.19 billion in 2024 and is projected to reach USD 18.85 billion by 2032, at a CAGR of 5.60% from 2025 to 2032. The global Multiple Drug Resistance Bacterial Infection Treatment Market was valued at USD 6,584.2 million in 2024 and is projected to reach USD 11,578.5 million by 2032, with a CAGR of 7.27%. Specifically for gram-negative bacterial infection therapeutics, the global market size was estimated at USD 5200.75 million (USD 5.2 billion) in 2025, with a projected CAGR of 4.85%. The global hospital-treated Gram-negative infections market size was valued at USD 10.87 billion in 2025 and is expected to reach USD 22.10 billion by 2033, at a CAGR of 9.28%. In 2025, North America dominated the hospital-treated Gram-negative infections market with a 37.2% revenue share.

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Matinas BioPharma (MTNB) is a clinical-stage biopharmaceutical company focusing on its lipid nanocrystal (LNC) platform technology for drug delivery and various product candidates. While the company is currently undergoing restructuring and has ceased product development activities to conserve cash following the termination of a key partnership for MAT2203, potential future revenue growth over the next 2-3 years could be driven by the following factors:

  1. Proceeds and potential future royalties from the asset sale of MAT2203: Following the termination of negotiations for a global partnership for MAT2203 in October 2024, Matinas BioPharma announced its intention to retain an advisor to assist with the potential asset sale of MAT2203. A successful sale of this Phase 3-ready antifungal drug candidate could provide upfront payments and potentially future milestone or royalty revenues, contingent on the acquiring company's successful development and commercialization.

  2. New collaborations leveraging the LNC platform technology: Despite the cessation of internal product development, Matinas BioPharma's proprietary lipid nanocrystal (LNC) platform technology remains a core asset, noted for its potential in delivering small molecules, nucleic acids, gene therapies, vaccines, proteins, and peptides. The company has previously engaged in research collaborations, generating revenue from agreements such as those with BioNTech and Genentech. Securing new partnerships that involve research funding, upfront payments, or milestones for the application of its LNC platform in new therapeutic areas, such as oncology and inflammation, could serve as a source of revenue.

  3. Monetization of intellectual property related to the LNC platform: The LNC platform is described as a unique and proprietary delivery technology. Should direct product collaborations be challenging, Matinas BioPharma may pursue broader licensing agreements for its intellectual property associated with the LNC platform. Such agreements could generate licensing fees, technology access fees, and potential royalties, contributing to revenue growth without requiring the extensive capital investment of internal product development.

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Share Issuance

  • In April 2024, Matinas BioPharma raised approximately $10 million through a registered direct offering to healthcare-focused institutional investors, involving the sale of over 33 million shares and associated warrants.
  • The company entered into an agreement in February 2025 for the acquisition of Series C Convertible Preferred Stock and warrants, projected to yield aggregate gross proceeds of $3.3 million.

Inbound Investments

  • Matinas BioPharma secured approximately $10 million in April 2024 from healthcare-focused institutional investors via a registered direct offering.
  • In February 2025, the company obtained $3.3 million in gross proceeds from investors through the sale of Preferred Stock and warrants.
  • The Cystic Fibrosis Foundation awarded Matinas BioPharma up to $3.75 million in 2021 to support the development of MAT2501 for nontuberculous mycobacterial lung disease.

Capital Expenditures

  • Matinas BioPharma reported minimal capital expenditures over the past few years, with figures including $0.0 million in 2024, -$0.9 million in 2023, and -$0.3 million in 2022. This indicates that significant capital outlay for physical assets is not a primary focus for the company.

Peer Outperformance in Biotechnology

MTNB has trailed 90% of its 361 Biotechnology peers over 5Y. Biotechnology ranks 10th of 10 industries in Health Care by median 5Y return. The sector’s gains have largely come from elsewhere.
Share of Biotechnology constituents that MTNB has outperformed, by holding period. Peers without a full price history over a given window are excluded from that window.
1Y
5%
of 455 industry peers · -89.9% return
3Y
9%
of 401 industry peers · -97.6% return
5Y
10%
of 361 industry peers · -99.7% return
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Median price return by industry across the Health Care sector, ranked by 5Y. Biotechnology is MTNB's own industry. Use this to see which corners of the sector have carried the returns.
Industry Names 1Y med3Y med5Y med Top 3 by 5Y
Health Care Distributors 7 7.1%86.3%123.6% CAH 402% · MCK 343% · COR 175%
Managed Health Care 8 43.7%-1.3%8.2% OSCR 84% · HQY 57% · ELV 23%
Health Care Services 20 18.9%44.9%0.0% HIMS 218% · RDNT 172% · DGX 67%
Health Care Facilities 24 3.7%7.9%-14.2% NHC 276% · THC 268% · ENSG 122%
Health Care Equipment 50 -1.7%-5.5%-25.7% POCI 10800% · UFPT 331% · GKOS 234%
Health Care Supplies 12 20.8%-12.1%-37.9% LNTH 308% · HAE 51% · MMSI 21%
Pharmaceuticals 62 -7.4%7.7%-40.7% LQDA 2457% · INDV 1136% · ETON 1063%
Life Sciences Tools & Services 109 -1.4%-25.5%-71.2% SNWV 1573% · MEDP 224% · NTRA 174%
Health Care Technology 20 -31.7%-52.2%-78.5% SPOK 77% · HSTM 3% · VEEV -12%
Biotechnology ← 362 1.6%-24.8%-79.6% DNTH 1632% · CELZ 1272% · ELVN 1222%
Median of constituents with a full price history over each window. Top names are unfiltered by size in this render.

Latest Trefis Analyses

TitleDate
0DASHBOARDS 
1Matinas BioPharma Earnings Notes12/16/2025
Title
0ARTICLES

Recent Active Movers

Peer Comparisons

Peers to compare with:

Financials

MTNBARWRALNYIONSABUSMRNAMedian
NameMatinas .Arrowhea.Alnylam .Ionis Ph.Arbutus .Moderna  
Mkt Price0.1882.85248.6854.215.12143.9768.53
Mkt Cap0.011.933.29.01.057.310.4
Rev LTM06694,8048741822,210772
Op Inc LTM-7-2261,000-594147-3,320-117
FCF LTM-6-75820-568-25-1,244-50
FCF 3Y Avg-12-208354-410-53-2,908-131
CFO LTM-6-59912-496-25-1,073-42
CFO 3Y Avg-12-130414-358-53-2,337-91

Growth & Margins

MTNBARWRALNYIONSABUSMRNAMedian
NameMatinas .Arrowhea.Alnylam .Ionis Ph.Arbutus .Moderna  
Rev Chg LTM-16.8%95.1%-7.4%1,078.8%-27.7%16.8%
Rev Chg 3Y Avg-913.6%63.2%12.5%358.2%-39.7%63.2%
Rev Chg Q-171.0%66.9%-40.7%-90.6%4.4%4.4%
QoQ Delta Rev Chg LTM-7.6%12.1%-17.4%-5.1%0.3%0.3%
Op Inc Chg LTM45.4%-109.7%654.9%-123.0%463.7%-1.4%22.0%
Op Inc Chg 3Y Avg29.8%-77.5%163.9%-24.5%168.1%-325.2%2.6%
Op Mgn LTM--33.8%20.8%-68.0%81.1%-150.2%-33.8%
Op Mgn 3Y Avg--945.9%6.0%-47.0%-333.7%-116.8%-116.8%
QoQ Delta Op Mgn LTM-1.9%3.3%-34.7%0.1%4.6%1.9%
CFO/Rev LTM--8.8%19.0%-56.8%-13.6%-48.6%-13.6%
CFO/Rev 3Y Avg--598.1%11.1%-41.2%-376.1%-67.3%-67.3%
FCF/Rev LTM--11.2%17.1%-64.9%-13.6%-56.3%-13.6%
FCF/Rev 3Y Avg--908.4%9.2%-47.1%-376.7%-83.5%-83.5%

Valuation

MTNBARWRALNYIONSABUSMRNAMedian
NameMatinas .Arrowhea.Alnylam .Ionis Ph.Arbutus .Moderna  
Mkt Cap0.011.933.29.01.057.310.4
P/S-17.76.910.35.625.910.3
P/Op Inc-0.2-52.533.2-15.16.9-17.3-7.6
P/EBIT-0.2-74.529.5-18.76.6-18.8-9.4
P/E-0.2-37.141.1-15.96.6-18.2-8.0
P/CFO-0.2-201.136.4-18.1-41.1-53.4-29.6
Total Yield-580.3%-2.7%2.4%-6.3%15.1%-5.5%-4.1%
Dividend Yield0.0%0.0%0.0%0.0%0.0%0.0%0.0%
FCF Yield 3Y Avg-151.0%-6.0%1.0%-4.8%-8.4%-15.3%-7.2%
D/E0.00.10.00.20.00.00.0
Net D/E-0.7-0.1-0.1-0.0-0.1-0.1-0.1

Returns

MTNBARWRALNYIONSABUSMRNAMedian
NameMatinas .Arrowhea.Alnylam .Ionis Ph.Arbutus .Moderna  
1M Rtn-20.9%-4.4%8.8%-5.3%9.6%127.4%2.2%
3M Rtn-76.3%11.2%-12.1%-26.0%20.2%188.5%-0.5%
6M Rtn-71.2%50.5%-20.7%-23.9%20.2%173.9%-0.2%
12M Rtn-89.9%178.8%-46.6%-14.2%14.8%512.4%0.3%
3Y Rtn-97.6%171.3%28.8%24.2%149.8%27.6%28.2%
1M Excs Rtn-21.7%-3.9%12.2%-2.9%12.7%127.3%4.7%
3M Excs Rtn-80.8%7.8%-17.6%-30.1%15.8%186.5%-4.9%
6M Excs Rtn-85.8%35.9%-36.4%-39.8%3.8%154.9%-16.3%
12M Excs Rtn-105.8%169.6%-64.2%-32.5%-6.4%475.0%-19.5%
3Y Excs Rtn-169.2%112.1%-48.0%-35.2%74.7%-38.5%-36.8%

Comparison Analyses

null

Financials

Segment Financials

Revenue by Segment
$ Mil20242023202220212020
Single Segment01300
Total01300


Assets by Segment
$ Mil2025202420232016
Single Segment7132510
Total7132510


Price Behavior

Price Behavior
Market Price$0.18 
Market Cap ($ Bil)0.0 
First Trading Date03/02/2017 
Distance from 52W High-91.0% 
   50 Days200 Days
DMA Price$0.32$0.57
DMA Trenddowndown
Distance from DMA-42.9%-67.4%
 3M1YR
Volatility161.6%115.1%
Downside Capture594.26237.85
Upside Capture-195.63-74.18
Correlation (SPY)6.7%3.8%
MTNB Betas & Captures as of 8/31/2026

 1M2M3M6M1Y3Y
Beta4.843.521.170.560.460.90
Up Beta-3.17-3.33-1.68-1.92-1.87-0.20
Down Beta22.835.160.380.091.141.40
Up Capture329%61%-83%16%-28%9%
Bmk +ve Days10213268138427
Stock +ve Days7142456110320
Down Capture1222%746%388%229%168%112%
Bmk -ve Days11213259113324
Stock -ve Days13273965131406

[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with MTNB
MTNB-88.7%115.1%-1.32-
Sector ETF (XLV)22.1%16.2%1.045.8%
Equity (SPY)18.3%12.8%1.034.1%
Gold (GLD)19.0%29.2%0.593.8%
Commodities (DBC)48.3%20.6%1.80-9.7%
Real Estate (VNQ)7.6%13.6%0.296.4%
Bitcoin (BTCUSD)-32.4%43.8%-0.778.3%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 5-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with MTNB
MTNB-64.8%182.2%0.00-
Sector ETF (XLV)5.5%15.2%0.186.7%
Equity (SPY)12.5%17.2%0.559.3%
Gold (GLD)18.7%18.8%0.812.5%
Commodities (DBC)11.4%19.5%0.46-2.0%
Real Estate (VNQ)0.7%18.9%-0.0710.9%
Bitcoin (BTCUSD)9.4%52.6%0.364.0%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 10-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with MTNB
MTNB-49.2%148.3%0.03-
Sector ETF (XLV)10.4%16.7%0.509.9%
Equity (SPY)15.2%17.9%0.7211.9%
Gold (GLD)12.3%16.3%0.623.3%
Commodities (DBC)8.7%18.1%0.392.3%
Real Estate (VNQ)4.7%20.7%0.199.9%
Bitcoin (BTCUSD)63.2%66.2%1.033.8%

Smart multi-asset allocation framework can stack odds in your favor. Learn How

Short Interest

Short Interest: As Of Date8312026
Short Interest: Shares Quantity0.3 Mil
Short Interest: % Change Since 815202639.0%
Average Daily Volume1.7 Mil
Days-to-Cover Short Interest1
Basic Shares Quantity6.4 Mil
Short % of Basic Shares4.9%

Earnings Returns History

Updated 9/4/2026
Expand for More
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
8/14/2024-2.5%-31.1%-51.1%
5/9/2024-0.6%-2.1%-10.5%
11/8/2023-12.2%-18.8%-9.5%
8/9/2023-40.9%-51.5%-50.7%
5/10/2023-29.7%-34.9%-44.4%
3/15/20236.9%-4.2%2.3%
11/2/2022-3.5%-9.6%-15.3%
8/11/2022-4.2%-11.4%-12.9%
...
SUMMARY STATS   
# Positive416
# Negative10138
Median Positive3.7%3.5%18.4%
Median Negative-4.6%-6.9%-14.1%
Max Positive6.9%3.5%49.1%
Max Negative-40.9%-51.5%-51.1%
Collapse to Preview
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
8/14/2024-2.5%-31.1%-51.1%
5/9/2024-0.6%-2.1%-10.5%
11/8/2023-12.2%-18.8%-9.5%
8/9/2023-40.9%-51.5%-50.7%
5/10/2023-29.7%-34.9%-44.4%
3/15/20236.9%-4.2%2.3%
11/2/2022-3.5%-9.6%-15.3%
8/11/2022-4.2%-11.4%-12.9%
5/12/20222.0%3.5%31.9%
3/8/20225.4%-3.1%49.1%
11/8/2021-5.6%-2.8%-5.6%
8/10/2021-5.0%-6.9%2.6%
5/10/2021-2.7%-3.2%5.5%
11/6/20200.1%-4.8%31.3%
SUMMARY STATS   
# Positive416
# Negative10138
Median Positive3.7%3.5%18.4%
Median Negative-4.6%-6.9%-14.1%
Max Positive6.9%3.5%49.1%
Max Negative-40.9%-51.5%-51.1%

SEC Filings

Expand for More
Report DateFiling DateFiling
06/30/202608/13/202610-Q
03/31/202605/08/202610-Q
12/31/202503/31/202610-K
09/30/202511/10/202510-Q
06/30/202508/14/202510-Q
03/31/202505/15/202510-Q
12/31/202404/15/202510-K
09/30/202411/13/202410-Q
06/30/202408/14/202410-Q
03/31/202405/09/202410-Q
12/31/202303/27/202410-K
09/30/202311/08/202310-Q
06/30/202308/09/202310-Q
03/31/202305/10/202310-Q
12/31/202203/15/202310-K
09/30/202211/02/202210-Q
Collapse to Preview
Report DateFiling DateFiling
06/30/202608/13/202610-Q
03/31/202605/08/202610-Q
12/31/202503/31/202610-K
09/30/202511/10/202510-Q
06/30/202508/14/202510-Q
03/31/202505/15/202510-Q
12/31/202404/15/202510-K
09/30/202411/13/202410-Q
06/30/202408/14/202410-Q
03/31/202405/09/202410-Q
12/31/202303/27/202410-K
09/30/202311/08/202310-Q
06/30/202308/09/202310-Q
03/31/202305/10/202310-Q
12/31/202203/15/202310-K
09/30/202211/02/202210-Q
06/30/202208/11/202210-Q
03/31/202205/12/202210-Q
12/31/202103/08/202210-K
09/30/202111/08/202110-Q
06/30/202108/10/202110-Q
03/31/202105/10/202110-Q
12/31/202003/29/202110-K
09/30/202011/06/202010-Q
06/30/202008/10/202010-Q
03/31/202005/11/202010-Q
12/31/201903/09/202010-K
09/30/201911/13/201910-Q
Core Cache Last Updated: 9/13/2026