Market Movers | Winners: KTTA, ZYXI, KALA | Losers: GORV, WHLR, PD

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On Wednesday, November 26, a market-wide surge lifted the S&P 500 rising 0.69%, the Dow 30 rising 0.67%, and the Nasdaq 100 rising 0.87%. Gains were broad-based, though not every stock joined the rally.
 

List of Market Winners

The following table shows the list of 10 stocks that generated the highest returns on the last trading day:
 

# Ticker Company Name 1-D
Returns
YTD
Returns
1 KTTA Pasithea Therapeutics 117.4% -66.3%
2 ZYXI Zynex 115.6% -80.1%
3 KALA Kala Bio 42.6% -86.9%
4 QNTM Quantum BioPharma 41.9% 210.1%
5 VRCA Verrica Pharmaceuticals 31.1% -4.1%
6 SBEV Splash Beverage 29.4% -79.5%
7 QNCX Quince Therapeutics 29.2% 84.5%
8 OSS One Stop Systems 29.1% 77.6%
9 GCTK GlucoTrack 23.5% -98.6%
10 ARWR Arrowhead Pharmaceuticals 23.3% 207.0%

 
List of Market Losers

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On the other hand, the following table shows the list of 10 stocks that generated the lowest returns:
 

# Ticker Company Name 1-D
Returns
YTD
Returns
1 GORV Lazydays -45.3% -98.5%
2 WHLR Wheeler Real Estate Investment Trust -27.7% -99.9%
3 PD PagerDuty -23.3% -36.3%
4 MBRX Moleculin Biotech -22.0% -83.5%
5 DGLY Digital Ally -21.1% -99.9%
6 IVP Inspire Veterinary Partners -20.8% -97.1%
7 AMBA Ambarella -18.8% 1.6%
8 SKIL Skillsoft -18.7% -56.3%
9 PHGE BiomX -18.7% -66.1%
10 SNT Senstar Technologies -18.3% 4.1%

 
Why does this matter? Significant stock moves – up or down – deserve your attention. Sharp declines in fundamentally strong names can offer smart buying opportunities. And when momentum aligns with solid fundamentals, riding the trend can be highly rewarding. Among the stocks above, we find PagerDuty (PD) attractive

Stock picking can fail no matter how good the strategy is. The Trefis High Quality Portfolio turns single-stock insights into a robust market-beating portfolio strategy.

Movers – Last One Week

Analysing over the last one week (5 trading days), a market-wide surge lifted the S&P 500 rising 2.57%, the Dow 30 rising 2.79%, and the Nasdaq 100 rising 2.42%. Gains were broad-based, though not every stock joined the rally.
 
List of 1-Week Market Winners

The following table shows the list of 10 stocks that generated the highest returns over the last week:
 

# Ticker Company Name 1-W
Returns
YTD
Returns
1 PHGE BiomX 1653.7% -66.1%
2 ZYXI Zynex 186.5% -80.1%
3 FOXX Foxx Development 163.2% -21.2%
4 KTTA Pasithea Therapeutics 122.7% -66.3%
5 AGRZ Agroz 94.4% 23.4%
6 PACS PACS 91.1% 145.3%
7 QNTM Quantum BioPharma 80.8% 210.1%
8 CETY Clean Energy Technologies 79.1% -77.6%
9 QNCX Quince Therapeutics 78.8% 84.5%
10 ALPS ALPS 74.1% 55.9%

 
List of 1-Week Market Losers

Similarly, the following table shows the 10 stocks that were at the bottom in terms of returns:
 

# Ticker Company Name 1-W
Returns
YTD
Returns
1 CLSD Clearside Biomedical -80.4% -96.1%
2 CMCT Creative Media & Community Trust -74.4% -94.1%
3 INHD Inno -69.5% -95.2%
4 BEAT HeartBeam -63.6% -73.8%
5 GORV Lazydays -59.5% -98.5%
6 HUSA Houston American Energy -54.5% -82.6%
7 TWNP Twin Hospitality -49.6% -89.5%
8 FAT FAT Brands -48.2% -90.0%
9 PBM Psyence Biomedical -43.4% -90.6%
10 CYPH Cypherpunk Technologies -42.5% -41.2%

 
Movers – Last One Month

On a slightly wider timeline over the last one month, all three indices fell — the S&P 500 falling 1.14%, the Dow 30 falling 0.59%, and the Nasdaq 100 falling 2.98%. Losses were widespread, though not universal.
 
List of 1-Month Market Winners

The following table shows the 10 stocks that generated the maximum returns over the last one month:
 

# Ticker Company Name 1-M
Returns
YTD
Returns
1 ADTX Aditxt 2298.8% -99.9%
2 Q Qnity Electronics 1060.0% 1060.0%
3 FLYE Fly-E 487.0% -94.7%
4 TERN Terns Pharmaceuticals 234.7% 419.0%
5 OLMA Olema Pharmaceuticals 222.5% 382.3%
6 CYPH Cypherpunk Technologies 216.4% -41.2%
7 PTN Palatin Technologies 185.4% 1429.7%
8 MRSN Mersana Therapeutics 169.2% -23.0%
9 PACS PACS 158.9% 145.3%
10 COGT Cogent Biosciences 151.0% 417.8%

 
List of 1-Month Market Losers

In the same period, these 10 stocks were at the bottom in terms of returns:
 

# Ticker Company Name 1-M
Returns
YTD
Returns
1 KRRO Korro Bio -86.2% -85.5%
2 CLSD Clearside Biomedical -85.6% -96.1%
3 CMND Clearmind Medicine -84.3% -88.8%
4 IVP Inspire Veterinary Partners -84.3% -97.1%
5 GORV Lazydays -80.8% -98.5%
6 MIGI Mawson Infrastructure -79.9% -69.1%
7 APLT Applied Therapeutics -79.7% -69.1%
8 INHD Inno -79.1% -95.2%
9 MVO MV Oil Trust -78.6% -84.5%
10 ECDA ECD Automotive Design -78.3% -98.6%

 

Picking winners on a consistent basis is not an easy task – especially given the volatility associated with a single stock. Instead, the Trefis High Quality (HQ) Portfolio, with a collection of 30 stocks, has a track record of comfortably outperforming its benchmark that includes all 3 — the S&P 500, S&P mid-cap, and Russell 2000 indices. Why is that? As a group, HQ Portfolio stocks provided better returns with less risk versus the benchmark index; less of a roller-coaster ride, as evident in HQ Portfolio performance metrics.