Tearsheet

Investment Highlights Why It Matters Which of these 2 stories sounds closer for this stock?

1. Generates cash flow

The stock generated 4% or more of the share price (called cash flow yield), and shows moderate 10-15% or more growth.

2. Riding a trend

Think Tesla during the pandemic of 2020 when EVs were riding a cultural high, or Nvidia in the current AI boom, or even Figma. These companies don’t have enough yield, or, enough growth, or both - however - they are riding a trend. They have momentum. These can be more volatile - they don’t have the floor of strong cash flow


0 Megatrend and thematic drivers
Megatrends include Precision Medicine, and Biotechnology & Genomics. Themes include Biopharmaceutical R&D, Gene Editing & Therapy, Show more.
Weak multi-year price returns
2Y Excs Rtn is -136%, 3Y Excs Rtn is -154%
Very low revenue
Rev LTMTotal Revenue or Sales, Last Twelve Months is 0
1   Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -19 Mil
2   Stock price has recently run up significantly
12M Rtn12 month market price return is 123%
3   Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -50%
4   High stock price volatility
Vol 12M is 197%
0 Megatrend and thematic drivers
Megatrends include Precision Medicine, and Biotechnology & Genomics. Themes include Biopharmaceutical R&D, Gene Editing & Therapy, Show more.
1 Weak multi-year price returns
2Y Excs Rtn is -136%, 3Y Excs Rtn is -154%
2 Very low revenue
Rev LTMTotal Revenue or Sales, Last Twelve Months is 0
3 Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -19 Mil
4 Stock price has recently run up significantly
12M Rtn12 month market price return is 123%
5 Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -50%
6 High stock price volatility
Vol 12M is 197%

Valuation, Metrics & Events

QNTM Stock


Why The Stock Moved


Qualitative Assessment

AI Generated Analysis | Feedback

For Quantum BioPharma (symbol: QNTM), for the approximate time period from August 31, 2025, to December 4, 2025, several key factors could explain a significant negative stock movement. These reasons stem from ongoing legal challenges, financial concerns, and market sentiment surrounding the company during this period.

1. Allegations of Mismanagement in Market Manipulation Lawsuit: While Quantum BioPharma has filed a USD $700 million lawsuit alleging stock market manipulation, the defendant banks, including CIBC and RBC, have countered these claims. They allege that Quantum's declining stock price was due to its own mismanagement and a consistent failure to turn a profit, potentially undermining investor confidence.

2. Negative Stock Signals and Forecasts: As of December 2025, analyses of QNTM indicate several negative signals, with a general sell signal from the long-term moving average. Experts believe the stock is likely to perform weakly, with one forecast suggesting a potential fall of over 50% in the subsequent three months.

Show more

Stock Movement Drivers

Return vs. Risk


Price Returns Compared

 202020212022202320242025Total [1]
Returns
QNTM Return-71%-35%-23%17%-94%164%-97%
Peers Return2%-1%6%8%-0%2%17%
S&P 500 Return16%27%-19%24%23%16%112%

Monthly Win Rates [3]
QNTM Win Rate25%33%42%50%17%50% 
Peers Win Rate13%8%13%12%10%90% 
S&P 500 Win Rate58%75%42%67%75%70% 

Max Drawdowns [4]
QNTM Max Drawdown-75%-38%-29%-2%-95%-21% 
Peers Max Drawdown-2%-5%0%-0%-1%-2% 
S&P 500 Max Drawdown-31%-1%-25%-1%-2%-15% 


[1] Cumulative total returns since the beginning of 2020
[2] Peers: VRTX, AIXC, ALPS, BBOT, EVMN.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2025 data is for the year up to 12/3/2025 (YTD)

How Low Can It Go

Unique KeyEventQNTMS&P 500
2022 Inflation Shock2022 Inflation Shock  
2022 Inflation Shock% Loss% Loss-81.2%-25.4%
2022 Inflation Shock% Gain to Breakeven% Gain to Breakeven431.2%34.1%
2022 Inflation ShockTime to BreakevenTime to BreakevenNot Fully Recovered days464 days
2020 Covid Pandemic2020 Covid Pandemic  
2020 Covid Pandemic% Loss% Loss-87.5%-33.9%
2020 Covid Pandemic% Gain to Breakeven% Gain to Breakeven698.4%51.3%
2020 Covid PandemicTime to BreakevenTime to BreakevenNot Fully Recovered days148 days
2018 Correction2018 Correction  
2018 Correction% Loss% Loss-94.1%-19.8%
2018 Correction% Gain to Breakeven% Gain to Breakeven1595.1%24.7%
2018 CorrectionTime to BreakevenTime to Breakeven1 days120 days

Compare to VRTX, AIXC, ALPS, BBOT, EVMN


In The Past

Quantum BioPharma's stock fell -81.2% during the 2022 Inflation Shock from a high on 2/10/2021. A -81.2% loss requires a 431.2% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth over time.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

About Quantum BioPharma (QNTM)

Better Bets than Quantum BioPharma (QNTM)

Trade Ideas

Select past ideas related to QNTM. For more, see Trefis Trade Ideas.

Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
CRL_11142025_Dip_Buyer_FCFYield11142025CRLCharles River Laboratories InternationalDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
4.1%4.1%-3.7%
GDRX_11142025_Dip_Buyer_High_CFO_Margins_ExInd_DE11142025GDRXGoodRxDip BuyDB | CFO/Rev | Low D/EDip Buy with High Cash Flow Margins
Buying dips for companies with significant cash flows from operations and reasonable debt / market cap
-9.8%-9.8%-11.8%
ASTH_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025ASTHAstrana HealthDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
6.0%6.0%-5.5%
SGRY_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025SGRYSurgery PartnersDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
9.7%9.7%-1.4%
TFX_11072025_Dip_Buyer_FCFYield11072025TFXTeleflexDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
6.2%6.2%-5.1%
Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
CRL_11142025_Dip_Buyer_FCFYield11142025CRLCharles River Laboratories InternationalDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
4.1%4.1%-3.7%
GDRX_11142025_Dip_Buyer_High_CFO_Margins_ExInd_DE11142025GDRXGoodRxDip BuyDB | CFO/Rev | Low D/EDip Buy with High Cash Flow Margins
Buying dips for companies with significant cash flows from operations and reasonable debt / market cap
-9.8%-9.8%-11.8%
ASTH_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025ASTHAstrana HealthDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
6.0%6.0%-5.5%
SGRY_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025SGRYSurgery PartnersDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
9.7%9.7%-1.4%
TFX_11072025_Dip_Buyer_FCFYield11072025TFXTeleflexDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
6.2%6.2%-5.1%

Recent Active Movers

Recent Active Movers

More From Trefis

Peer Comparisons for Quantum BioPharma

Peers to compare with:

Financials

QNTMVRTXAIXCALPSBBOTEVMNMedian
NameQuantum .Vertex P.AIxCryptoALPS BridgeBi.Evommune  
Mkt Price9.99463.132.541.0711.0721.2210.53
Mkt Cap0.0118.4----59.2
Rev LTM011,7230-0100
Op Inc LTM-19-92-5--93-70-70
FCF LTM-93,337-6--60-64-9
FCF 3Y Avg-112,064-10----10
CFO LTM-93,718-6--60-64-9
CFO 3Y Avg-112,419-10----10

Growth & Margins

QNTMVRTXAIXCALPSBBOTEVMNMedian
NameQuantum .Vertex P.AIxCryptoALPS BridgeBi.Evommune  
Rev Chg LTM-10.3%----10.3%
Rev Chg 3Y Avg-10.5%----10.5%
Rev Chg Q-11.0%----11.0%
QoQ Delta Rev Chg LTM-2.7%----2.7%
Op Mgn LTM--0.8%----700.7%-350.7%
Op Mgn 3Y Avg-26.2%----26.2%
QoQ Delta Op Mgn LTM-1.0%----1.0%
CFO/Rev LTM-31.7%----635.6%-302.0%
CFO/Rev 3Y Avg-23.1%----23.1%
FCF/Rev LTM-28.5%----636.5%-304.0%
FCF/Rev 3Y Avg-19.8%----19.8%

Valuation

QNTMVRTXAIXCALPSBBOTEVMNMedian
NameQuantum .Vertex P.AIxCryptoALPS BridgeBi.Evommune  
Mkt Cap0.0118.4----59.2
P/S-8.5----8.5
P/EBIT-2.222.4----10.1
P/E-2.227.2----12.5
P/CFO-7.126.9----9.9
Total Yield-45.7%3.7%-----21.0%
Dividend Yield0.0%0.0%----0.0%
FCF Yield 3Y Avg-78.7%2.3%-----38.2%
D/E0.00.0----0.0
Net D/E0.0-0.0-----0.0

Returns

QNTMVRTXAIXCALPSBBOTEVMNMedian
NameQuantum .Vertex P.AIxCryptoALPS BridgeBi.Evommune  
1M Rtn-5.0%8.7%---9.9%--5.0%
3M Rtn-36.4%16.8%--12.5%-12.5%
6M Rtn-31.2%3.9%-----13.7%
12M Rtn123.5%1.3%----62.4%
3Y Rtn-82.5%44.1%-----19.2%
1M Excs Rtn-5.0%8.7%---9.9%--5.0%
3M Excs Rtn-35.4%11.3%--4.5%-4.5%
6M Excs Rtn-46.0%-10.8%-----28.4%
12M Excs Rtn100.4%-14.6%----42.9%
3Y Excs Rtn-154.3%-25.9%-----90.1%

Financials

Segment Financials

Assets by Segment

$ Mil20242023202220212020
Biopharmaceutical14931  
Strategic Investments387  
Single Segment   6342
Total1717386342


Price Behavior

Short Interest

Short Interest: As Of Date11142025
Short Interest: Shares Quantity32,912
Short Interest: % Change Since 1031202531.3%
Average Daily Volume58,639
Days-to-Cover Short Interest1
Basic Shares Quantity3,801,151
Short % of Basic Shares0.9%

SEC Filings

Expand for More

Report DateFiling DateFiling
9302025110620256-K 9/30/2025
630202580720256-K 6/30/2025
331202551420256-K 3/31/2025
12312024328202520-F 12/31/2024
9302024111220246-K 9/30/2024
630202481420246-K 6/30/2024
331202451520246-K 3/31/2024
12312023402202420-F 12/31/2023
9302023111520236-K 9/30/2023
630202372020236-K 6/30/2023
331202351520236-K 3/31/2023
12312022331202320-F 12/31/2022
9302022111420226-K 9/30/2022
630202281220226-K 6/30/2022
331202251320226-K 3/31/2022
12312021331202220-F 12/31/2021