Market Movers | Winners: ASST, ADIL, RLYB | Losers: EAF, ERNA, ANEB

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On Friday, February 6, stocks moved decisively higher, as seen in the S&P 500 rising 1.97%, the Dow 30 rising 2.47%, and the Nasdaq 100 rising 2.15%. Most stocks saw buying, though some stocks missed out.
 

Trefis

List of Market Winners

The following table shows the list of 10 stocks that generated the highest returns on the last trading day:
 

# Ticker Company Name 1-D
Returns
YTD
Returns
1 ASST Strive 2316.3% -19.3%
2 ADIL Adial Pharmaceuticals 2177.4% -43.3%
3 RLYB Rallybio 717.0% -13.5%
4 PLSE Pulse Biosciences 51.6% 51.1%
5 CCHH CCH 50.6% 12.2%
6 HURA TuHURA Biosciences 43.0% -16.9%
7 BILL BILL 37.2% -10.3%
8 SLNH Soluna 34.7% -12.8%
9 BGMS Bio Green Med Solution 33.7% -25.0%
10 DVLT Datavault AI 32.9% 30.4%

 
List of Market Losers

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On the other hand, the following table shows the list of 10 stocks that generated the lowest returns:
 

# Ticker Company Name 1-D
Returns
YTD
Returns
1 EAF GrafTech International -46.2% -45.6%
2 ERNA Ernexa Therapeutics -44.7% -68.6%
3 ANEB Anebulo Pharmaceuticals -39.1% -50.4%
4 LASE Laser Photonics -38.4% -75.7%
5 ASYS Amtech Systems -29.9% -11.4%
6 HCTI Healthcare Triangle -28.8% -75.6%
7 RBBN Ribbon Communications -27.9% -31.9%
8 GITS Global Interactive Technologies -25.7% 288.7%
9 MOH Molina Healthcare -25.5% -24.1%
10 PI Impinj -24.6% -33.3%

 
Why does this matter? Significant stock moves – up or down – deserve your attention. Sharp declines in fundamentally strong names can offer smart buying opportunities. And when momentum aligns with solid fundamentals, riding the trend can be highly rewarding.

Individual stocks can be volatile, but markets aren’t spared either. Think 2008 and 2020. Volatility happens. See how Trefis’ Boston-based wealth management partner’s asset allocation framework handled both.

Movers – Last One Week

Analysing over the last one week (5 trading days), index performance was mixed — the S&P 500 falling 0.10%, the Dow 30 rising 2.50%, and the Nasdaq 100 falling 1.87% offered no clear consensus. Stock-specific factors shaped outcomes throughout the market.
 
List of 1-Week Market Winners

The following table shows the list of 10 stocks that generated the highest returns over the last week:
 

# Ticker Company Name 1-W
Returns
YTD
Returns
1 ADIL Adial Pharmaceuticals 1364.8% -43.3%
2 ASST Strive 1351.1% -19.3%
3 ATOS Atossa Therapeutics 845.1% -39.7%
4 EDBL Edible Garden 642.4% -40.8%
5 RLYB Rallybio 639.8% -13.5%
6 PBM Psyence Biomedical 388.6% -89.4%
7 AREB American Rebel 289.5% -92.2%
8 LIMN Liminatus Pharma 234.4% 201.6%
9 EGHT 8×8 57.8% 33.0%
10 POAS Phaos Technology Cayman 55.6% 75.5%

 
List of 1-Week Market Losers

Similarly, the following table shows the 10 stocks that were at the bottom in terms of returns:
 

# Ticker Company Name 1-W
Returns
YTD
Returns
1 AHMA Ambitions Enterprise Management -77.3% 39.3%
2 ERNA Ernexa Therapeutics -69.2% -68.6%
3 LASE Laser Photonics -69.0% -75.7%
4 MAMO Massimo -65.9% -72.6%
5 NBY NovaBay Pharmaceuticals -59.1% -86.5%
6 MPT SALOMON BROTHERS MUNI PARTNERS FUND II. -57.9% -57.9%
7 ANEB Anebulo Pharmaceuticals -52.3% -50.4%
8 SMTK SmartKem -50.7% -62.8%
9 ELAB PMGC -49.9% -70.3%
10 IVDA Iveda Solutions -48.1% -45.6%

 
Movers – Last One Month

On a slightly wider timeline over the last one month, markets were split, as the S&P 500 rising 0.16%, the Dow 30 rising 2.29%, and the Nasdaq 100 falling 2.25% moved in different directions. Similar variation was seen across individual stocks.
 
List of 1-Month Market Winners

The following table shows the 10 stocks that generated the maximum returns over the last one month:
 

# Ticker Company Name 1-M
Returns
YTD
Returns
1 AKTS Aktis Oncology ∞% ∞%
2 CRAN Crane Harbor Acquisition II 49900.0% 49900.0%
3 LIFE Ethos Technologies 1451.1% 1451.1%
4 VMAR Vision Marine Technologies 1402.3% -62.5%
5 BNAI Brand Engagement Network 497.1% 867.7%
6 DSAC Daedalus Special Acquisition 487.1% 578.9%
7 EVTV Envirotech Vehicles 341.4% 515.4%
8 GITS Global Interactive Technologies 246.6% 288.7%
9 LVLU Lulus Fashion Lounge 206.4% 249.8%
10 OPTX Syntec Optics 195.6% 204.9%

 
List of 1-Month Market Losers

In the same period, these 10 stocks were at the bottom in terms of returns:
 

# Ticker Company Name 1-M
Returns
YTD
Returns
1 QNCX Quince Therapeutics -95.2% -95.8%
2 AREB American Rebel -92.9% -92.2%
3 NBY NovaBay Pharmaceuticals -92.9% -86.5%
4 PBM Psyence Biomedical -89.9% -89.4%
5 CALC CalciMedica -89.6% -90.9%
6 ELME Elme Communities -87.2% -87.2%
7 LHAI Linkhome -81.4% -82.3%
8 GUTS Fractyl Health -80.1% -81.1%
9 MTVA MetaVia -79.2% -78.4%
10 LRHC La Rosa -78.1% -75.1%

 

Picking winners on a consistent basis is not an easy task – especially given the volatility associated with a single stock. Instead, the Trefis High Quality (HQ) Portfolio, with a collection of 30 stocks, has a track record of comfortably outperforming its benchmark that includes all 3 — the S&P 500, S&P mid-cap, and Russell 2000 indices. Why is that? As a group, HQ Portfolio stocks provided better returns with less risk versus the benchmark index; less of a roller-coaster ride, as evident in HQ Portfolio performance metrics.