Market Movers | Winners: ASST, ADIL, RLYB | Losers: EAF, ERNA, ANEB
On Friday, February 6, stocks moved decisively higher, as seen in the S&P 500 rising 1.97%, the Dow 30 rising 2.47%, and the Nasdaq 100 rising 2.15%. Most stocks saw buying, though some stocks missed out.

List of Market Winners
The following table shows the list of 10 stocks that generated the highest returns on the last trading day:
| # | Ticker | Company Name | 1-D Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | ASST | Strive | 2316.3% | -19.3% |
| 2 | ADIL | Adial Pharmaceuticals | 2177.4% | -43.3% |
| 3 | RLYB | Rallybio | 717.0% | -13.5% |
| 4 | PLSE | Pulse Biosciences | 51.6% | 51.1% |
| 5 | CCHH | CCH | 50.6% | 12.2% |
| 6 | HURA | TuHURA Biosciences | 43.0% | -16.9% |
| 7 | BILL | BILL | 37.2% | -10.3% |
| 8 | SLNH | Soluna | 34.7% | -12.8% |
| 9 | BGMS | Bio Green Med Solution | 33.7% | -25.0% |
| 10 | DVLT | Datavault AI | 32.9% | 30.4% |
List of Market Losers
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- Does Caterpillar Stock Have More Upside?
- Is Royal Caribbean Stock Poised for a Rally?
On the other hand, the following table shows the list of 10 stocks that generated the lowest returns:
| # | Ticker | Company Name | 1-D Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | EAF | GrafTech International | -46.2% | -45.6% |
| 2 | ERNA | Ernexa Therapeutics | -44.7% | -68.6% |
| 3 | ANEB | Anebulo Pharmaceuticals | -39.1% | -50.4% |
| 4 | LASE | Laser Photonics | -38.4% | -75.7% |
| 5 | ASYS | Amtech Systems | -29.9% | -11.4% |
| 6 | HCTI | Healthcare Triangle | -28.8% | -75.6% |
| 7 | RBBN | Ribbon Communications | -27.9% | -31.9% |
| 8 | GITS | Global Interactive Technologies | -25.7% | 288.7% |
| 9 | MOH | Molina Healthcare | -25.5% | -24.1% |
| 10 | PI | Impinj | -24.6% | -33.3% |
Why does this matter? Significant stock moves – up or down – deserve your attention. Sharp declines in fundamentally strong names can offer smart buying opportunities. And when momentum aligns with solid fundamentals, riding the trend can be highly rewarding.
Individual stocks can be volatile, but markets aren’t spared either. Think 2008 and 2020. Volatility happens. See how Trefis’ Boston-based wealth management partner’s asset allocation framework handled both.
Movers – Last One Week
Analysing over the last one week (5 trading days), index performance was mixed — the S&P 500 falling 0.10%, the Dow 30 rising 2.50%, and the Nasdaq 100 falling 1.87% offered no clear consensus. Stock-specific factors shaped outcomes throughout the market.
List of 1-Week Market Winners
The following table shows the list of 10 stocks that generated the highest returns over the last week:
| # | Ticker | Company Name | 1-W Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | ADIL | Adial Pharmaceuticals | 1364.8% | -43.3% |
| 2 | ASST | Strive | 1351.1% | -19.3% |
| 3 | ATOS | Atossa Therapeutics | 845.1% | -39.7% |
| 4 | EDBL | Edible Garden | 642.4% | -40.8% |
| 5 | RLYB | Rallybio | 639.8% | -13.5% |
| 6 | PBM | Psyence Biomedical | 388.6% | -89.4% |
| 7 | AREB | American Rebel | 289.5% | -92.2% |
| 8 | LIMN | Liminatus Pharma | 234.4% | 201.6% |
| 9 | EGHT | 8×8 | 57.8% | 33.0% |
| 10 | POAS | Phaos Technology Cayman | 55.6% | 75.5% |
List of 1-Week Market Losers
Similarly, the following table shows the 10 stocks that were at the bottom in terms of returns:
| # | Ticker | Company Name | 1-W Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | AHMA | Ambitions Enterprise Management | -77.3% | 39.3% |
| 2 | ERNA | Ernexa Therapeutics | -69.2% | -68.6% |
| 3 | LASE | Laser Photonics | -69.0% | -75.7% |
| 4 | MAMO | Massimo | -65.9% | -72.6% |
| 5 | NBY | NovaBay Pharmaceuticals | -59.1% | -86.5% |
| 6 | MPT | SALOMON BROTHERS MUNI PARTNERS FUND II. | -57.9% | -57.9% |
| 7 | ANEB | Anebulo Pharmaceuticals | -52.3% | -50.4% |
| 8 | SMTK | SmartKem | -50.7% | -62.8% |
| 9 | ELAB | PMGC | -49.9% | -70.3% |
| 10 | IVDA | Iveda Solutions | -48.1% | -45.6% |
Movers – Last One Month
On a slightly wider timeline over the last one month, markets were split, as the S&P 500 rising 0.16%, the Dow 30 rising 2.29%, and the Nasdaq 100 falling 2.25% moved in different directions. Similar variation was seen across individual stocks.
List of 1-Month Market Winners
The following table shows the 10 stocks that generated the maximum returns over the last one month:
| # | Ticker | Company Name | 1-M Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | AKTS | Aktis Oncology | ∞% | ∞% |
| 2 | CRAN | Crane Harbor Acquisition II | 49900.0% | 49900.0% |
| 3 | LIFE | Ethos Technologies | 1451.1% | 1451.1% |
| 4 | VMAR | Vision Marine Technologies | 1402.3% | -62.5% |
| 5 | BNAI | Brand Engagement Network | 497.1% | 867.7% |
| 6 | DSAC | Daedalus Special Acquisition | 487.1% | 578.9% |
| 7 | EVTV | Envirotech Vehicles | 341.4% | 515.4% |
| 8 | GITS | Global Interactive Technologies | 246.6% | 288.7% |
| 9 | LVLU | Lulus Fashion Lounge | 206.4% | 249.8% |
| 10 | OPTX | Syntec Optics | 195.6% | 204.9% |
List of 1-Month Market Losers
In the same period, these 10 stocks were at the bottom in terms of returns:
| # | Ticker | Company Name | 1-M Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | QNCX | Quince Therapeutics | -95.2% | -95.8% |
| 2 | AREB | American Rebel | -92.9% | -92.2% |
| 3 | NBY | NovaBay Pharmaceuticals | -92.9% | -86.5% |
| 4 | PBM | Psyence Biomedical | -89.9% | -89.4% |
| 5 | CALC | CalciMedica | -89.6% | -90.9% |
| 6 | ELME | Elme Communities | -87.2% | -87.2% |
| 7 | LHAI | Linkhome | -81.4% | -82.3% |
| 8 | GUTS | Fractyl Health | -80.1% | -81.1% |
| 9 | MTVA | MetaVia | -79.2% | -78.4% |
| 10 | LRHC | La Rosa | -78.1% | -75.1% |
Picking winners on a consistent basis is not an easy task – especially given the volatility associated with a single stock. Instead, the Trefis High Quality (HQ) Portfolio, with a collection of 30 stocks, has a track record of comfortably outperforming its benchmark that includes all 3 — the S&P 500, S&P mid-cap, and Russell 2000 indices. Why is that? As a group, HQ Portfolio stocks provided better returns with less risk versus the benchmark index; less of a roller-coaster ride, as evident in HQ Portfolio performance metrics.