Market Movers | Winners: HYLN, FJET, MEHA | Losers: TSEOF, AMSS, ADTX
On Friday, May 22, all major indices rose in unison — the S&P 500 rising 0.37%, the Dow 30 rising 0.58%, and the Nasdaq 100 rising 0.42%. The strength was widespread, though a few names underperformed.

List of Market Winners
The following table shows the list of 10 stocks that generated the highest returns on the last trading day:
| # | Ticker | Company Name | 1-D Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | HYLN | Hyliion | 42.6% | 225.5% |
| 2 | FJET | Starfighters Space | 39.8% | -38.2% |
| 3 | MEHA | Functional Brands | 38.7% | -43.9% |
| 4 | CODX | Co-Diagnostics | 36.7% | 0.2% |
| 5 | MTVA | MetaVia | 33.2% | -54.3% |
| 6 | GOVX | Geovax Labs | 32.4% | -14.9% |
| 7 | FEMY | Femasys | 29.9% | -24.0% |
| 8 | CPSH | CPS Technologies | 28.5% | 94.2% |
| 9 | AIB | BlockchAIn Digital Infrastructure | 27.7% | -88.9% |
| 10 | WW | WW International | 26.8% | -56.2% |
List of Market Losers
On the other hand, the following table shows the list of 10 stocks that generated the lowest returns:
| # | Ticker | Company Name | 1-D Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | TSEOF | Trinseo | -90.0% | -97.7% |
| 2 | AMSS | Amass Brands | -61.9% | -61.9% |
| 3 | ADTX | Aditxt | -57.8% | -99.7% |
| 4 | NGEN | NervGen Pharma | -43.5% | -65.2% |
| 5 | BDTX | Black Diamond Therapeutics | -35.8% | -6.2% |
| 6 | BTM | Bitcoin Depot | -31.5% | -94.6% |
| 7 | LIMN | Liminatus Pharma | -31.1% | -72.2% |
| 8 | NXTC | NextCure | -23.2% | -44.8% |
| 9 | WGRX | Wellgistics Health | -22.7% | -79.3% |
| 10 | ATPC | Agape ATP | -22.6% | -47.8% |
Why does this matter? Significant stock moves – up or down – deserve your attention. Sharp declines in fundamentally strong names can offer smart buying opportunities. And when momentum aligns with solid fundamentals, riding the trend can be highly rewarding.
Don’t get too attached to RUA stock, even if you love it. Stocks crash. The Trefis High Quality Portfolio lets you navigate that risk.
Movers – Last One Week
Analyzing over the last week (5 trading days), a market-wide surge lifted the S&P 500, rising 0.88%; the Dow 30, rising 2.13%; and the Nasdaq 100, rising 1.22%. Gains were broad-based, though not every stock joined the rally.
List of 1-Week Market Winners
The following table shows the list of 10 stocks that generated the highest returns over the last week:
| # | Ticker | Company Name | 1-W Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | CODX | Co-Diagnostics | 294.6% | 0.2% |
| 2 | MTVA | MetaVia | 246.8% | -54.3% |
| 3 | NXXT | NextNRG | 207.1% | -40.6% |
| 4 | GOVX | Geovax Labs | 195.9% | -14.9% |
| 5 | INM | InMed Pharmaceuticals | 168.7% | 62.3% |
| 6 | AMST | Amesite | 154.9% | 11.1% |
| 7 | HCWB | HCW Biologics | 136.9% | 197.8% |
| 8 | BIGGQ | Former BL Stores | 133.3% | 133.3% |
| 9 | NCPL | Netcapital | 117.6% | 24.1% |
| 10 | AIB | BlockchAIn Digital Infrastructure | 95.1% | -88.9% |
List of 1-Week Market Losers
Similarly, the following table shows the 10 stocks that were at the bottom in terms of returns:
| # | Ticker | Company Name | 1-W Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | TSEOF | Trinseo | -90.0% | -97.7% |
| 2 | BTM | Bitcoin Depot | -83.2% | -94.6% |
| 3 | ADTX | Aditxt | -69.8% | -99.7% |
| 4 | DBGI | Digital Brands | -68.0% | -97.2% |
| 5 | BNZI | Banzai International | -55.0% | -82.1% |
| 6 | IPST | IP Strategy | -54.3% | -85.8% |
| 7 | LABT | Lakewood-Amedex Biotherapeutics | -52.9% | -91.8% |
| 8 | NGEN | NervGen Pharma | -41.7% | -65.2% |
| 9 | CDT | CDT Equity | -39.1% | -99.9% |
| 10 | GOSS | Gossamer Bio | -38.2% | -93.2% |
Movers – Last One Month
On a slightly wider timeline over the last one month, all major indices rose in unison — the S&P 500 rising 5.14%, the Dow 30 rising 2.57%, and the Nasdaq 100 rising 10.08%. The strength was widespread, though a few names underperformed.
List of 1-Month Market Winners
The following table shows the 10 stocks that generated the maximum returns over the last one month:
| # | Ticker | Company Name | 1-M Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | BIGGQ | Former BL Stores | ∞% | 133.3% |
| 2 | VIDA | Vida Global | ∞% | ∞% |
| 3 | CHRN | ChronoScale | 407400.0% | 407400.0% |
| 4 | HCWB | HCW Biologics | 606.1% | 197.8% |
| 5 | PIII | P3 Health Partners | 386.2% | 278.2% |
| 6 | AGL | Agilon Health | 228.2% | 401.8% |
| 7 | HYLN | Hyliion | 216.9% | 225.5% |
| 8 | GOVX | Geovax Labs | 216.5% | -14.9% |
| 9 | CODX | Co-Diagnostics | 196.5% | 0.2% |
| 10 | BZFD | BuzzFeed | 195.8% | 124.7% |
List of 1-Month Market Losers
In the same period, these 10 stocks were at the bottom in terms of returns:
| # | Ticker | Company Name | 1-M Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | GDC | GD Culture | -97.3% | -97.4% |
| 2 | ADTX | Aditxt | -93.4% | -99.7% |
| 3 | BTM | Bitcoin Depot | -93.3% | -94.6% |
| 4 | LABT | Lakewood-Amedex Biotherapeutics | -91.8% | -91.8% |
| 5 | SDOT | Sadot | -90.1% | -86.8% |
| 6 | TSEOF | Trinseo | -85.0% | -97.7% |
| 7 | PMI | Picard Medical | -82.1% | -91.4% |
| 8 | ENGN | enGene Therapeutics | -79.9% | -81.8% |
| 9 | JAGX | Jaguar Health | -78.9% | -91.1% |
| 10 | DBGI | Digital Brands | -76.4% | -97.2% |
Picking winners on a consistent basis is not an easy task – especially given the volatility associated with a single stock. Instead, the Trefis High Quality (HQ) Portfolio, with a collection of 30 stocks, has a track record of comfortably outperforming its benchmark that includes all 3 — the S&P 500, S&P mid-cap, and Russell 2000 indices. Why is that? As a group, HQ Portfolio stocks provided better returns with less risk versus the benchmark index, less of a roller-coaster ride, as is evident in HQ Portfolio performance metrics.