enGene Therapeutics (ENGN)
Market Price (4/15/2026): $7.59 | Market Cap: $510.5 MilSector: Health Care | Industry: Biotechnology
enGene Therapeutics (ENGN)
Market Price (4/15/2026): $7.59Market Cap: $510.5 MilSector: Health CareIndustry: Biotechnology
Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.
Cash is significant % of market capNet D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -47% Megatrend and thematic driversMegatrends include Biotechnology & Genomics, and Precision Medicine. Themes include Gene Editing & Therapy, Targeted Therapies, Show more. | Weak multi-year price returns2Y Excs Rtn is -87%, 3Y Excs Rtn is -132% | Very low revenueRev LTMTotal Revenue or Sales, Last Twelve Months is 0 Not profitable at operating income levelOp Inc LTMOperating Income, Last Twelve Months is -128 Mil Yield minus risk free rate is negativeERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -28% Key risksENGN key risks include [1] a near-total reliance on the success of its single product candidate, Show more. |
| Cash is significant % of market capNet D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -47% |
| Megatrend and thematic driversMegatrends include Biotechnology & Genomics, and Precision Medicine. Themes include Gene Editing & Therapy, Targeted Therapies, Show more. |
| Weak multi-year price returns2Y Excs Rtn is -87%, 3Y Excs Rtn is -132% |
| Very low revenueRev LTMTotal Revenue or Sales, Last Twelve Months is 0 |
| Not profitable at operating income levelOp Inc LTMOperating Income, Last Twelve Months is -128 Mil |
| Yield minus risk free rate is negativeERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -28% |
| Key risksENGN key risks include [1] a near-total reliance on the success of its single product candidate, Show more. |
Qualitative Assessment
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enGene Therapeutics (ENGN) stock has lost about 15% since 12/31/2025 because of the following key factors:
1. EnGene's stock experienced a significant decline of over 20% following its First Quarter 2026 earnings report on March 9, 2026. This sharp drop occurred despite the company reporting an earnings per share (EPS) of -$0.44, which beat analysts' consensus estimate of -$0.55 by $0.11. The market's negative reaction, leading to a 20.05% price change downward in the 48-hour period after the announcement, suggests that other factors overshadowed the EPS beat.
2. The company reported increased operating expenses and an expanding net loss in Q1 2026. For the three months ended January 31, 2026, enGene's total operating expenses rose to $31.2 million, up from $26.6 million in the same period of 2025. Consequently, the net loss attributable to common shareholders increased to approximately $29.8 million (or -$0.44 per share), compared to approximately $24.6 million (or -$0.48 per share) for the three months ended January 31, 2025. This growing cash burn, despite a better-than-expected EPS, likely raised investor concerns about future profitability and financial sustainability.
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1. EnGene's stock experienced a significant decline of over 20% following its First Quarter 2026 earnings report on March 9, 2026. This sharp drop occurred despite the company reporting an earnings per share (EPS) of -$0.44, which beat analysts' consensus estimate of -$0.55 by $0.11. The market's negative reaction, leading to a 20.05% price change downward in the 48-hour period after the announcement, suggests that other factors overshadowed the EPS beat.
2. The company reported increased operating expenses and an expanding net loss in Q1 2026. For the three months ended January 31, 2026, enGene's total operating expenses rose to $31.2 million, up from $26.6 million in the same period of 2025. Consequently, the net loss attributable to common shareholders increased to approximately $29.8 million (or -$0.44 per share), compared to approximately $24.6 million (or -$0.48 per share) for the three months ended January 31, 2025. This growing cash burn, despite a better-than-expected EPS, likely raised investor concerns about future profitability and financial sustainability.
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Stock Movement Drivers
Fundamental Drivers
The -15.8% change in ENGN stock from 12/31/2025 to 4/14/2026 was primarily driven by a -23.6% change in the company's Shares Outstanding (Mil).| (LTM values as of) | 12312025 | 4142026 | Change |
|---|---|---|---|
| Stock Price ($) | 9.03 | 7.60 | -15.8% |
| Change Contribution By: | |||
| Total Revenues ($ Mil) | 0 | 0 | 0.0% |
| P/S Multiple | ∞ | ∞ | 0.0% |
| Shares Outstanding (Mil) | 51 | 67 | -23.6% |
| Cumulative Contribution | 0.0% |
Market Drivers
12/31/2025 to 4/14/2026| Return | Correlation | |
|---|---|---|
| ENGN | -15.8% | |
| Market (SPY) | -5.4% | 15.2% |
| Sector (XLV) | -3.9% | 13.5% |
Fundamental Drivers
The 11.3% change in ENGN stock from 9/30/2025 to 4/14/2026 was primarily driven by a 0.0% change in the company's Total Revenues ($ Mil).| (LTM values as of) | 9302025 | 4142026 | Change |
|---|---|---|---|
| Stock Price ($) | 6.83 | 7.60 | 11.3% |
| Change Contribution By: | |||
| Total Revenues ($ Mil) | 0 | 0 | 0.0% |
| P/S Multiple | ∞ | ∞ | 0.0% |
| Shares Outstanding (Mil) | 51 | 67 | -24.0% |
| Cumulative Contribution | 0.0% |
Market Drivers
9/30/2025 to 4/14/2026| Return | Correlation | |
|---|---|---|
| ENGN | 11.3% | |
| Market (SPY) | -2.9% | 24.4% |
| Sector (XLV) | 7.4% | 26.1% |
Fundamental Drivers
The 69.6% change in ENGN stock from 3/31/2025 to 4/14/2026 was primarily driven by a 0.0% change in the company's Total Revenues ($ Mil).| (LTM values as of) | 3312025 | 4142026 | Change |
|---|---|---|---|
| Stock Price ($) | 4.48 | 7.60 | 69.6% |
| Change Contribution By: | |||
| Total Revenues ($ Mil) | 0 | 0 | 0.0% |
| P/S Multiple | ∞ | ∞ | 0.0% |
| Shares Outstanding (Mil) | 51 | 67 | -24.2% |
| Cumulative Contribution | 0.0% |
Market Drivers
3/31/2025 to 4/14/2026| Return | Correlation | |
|---|---|---|
| ENGN | 69.6% | |
| Market (SPY) | 16.3% | 10.8% |
| Sector (XLV) | 3.3% | 19.1% |
Fundamental Drivers
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Market Drivers
3/31/2023 to 4/14/2026| Return | Correlation | |
|---|---|---|
| ENGN | ||
| Market (SPY) | 63.3% | 6.8% |
| Sector (XLV) | 20.4% | 8.4% |
Price Returns Compared
| 2021 | 2022 | 2023 | 2024 | 2025 | 2026 | Total [1] | |
|---|---|---|---|---|---|---|---|
| Returns | |||||||
| ENGN Return | - | - | -54% | -28% | 36% | -20% | -64% |
| Peers Return | -7% | 32% | 41% | -1% | 2% | 4% | 81% |
| S&P 500 Return | 27% | -19% | 24% | 23% | 16% | -0% | 81% |
Monthly Win Rates [3] | |||||||
| ENGN Win Rate | - | - | 50% | 42% | 58% | 75% | |
| Peers Win Rate | 42% | 67% | 58% | 50% | 67% | 40% | |
| S&P 500 Win Rate | 75% | 42% | 67% | 75% | 67% | 50% | |
Max Drawdowns [4] | |||||||
| ENGN Max Drawdown | - | - | -65% | -43% | -57% | -32% | |
| Peers Max Drawdown | -25% | 0% | -2% | -3% | -23% | -12% | |
| S&P 500 Max Drawdown | -1% | -25% | -1% | -2% | -15% | -7% | |
[1] Cumulative total returns since the beginning of 2021
[2] Peers: VRTX, ALPS, DFTX, EIKN, GENB.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 4/14/2026 (YTD)
How Low Can It Go
ENGN has limited trading history. Below is the Health Care sector ETF (XLV) in its place.
| Event | XLV | S&P 500 |
|---|---|---|
| 2022 Inflation Shock | ||
| % Loss | -16.1% | -25.4% |
| % Gain to Breakeven | 19.1% | 34.1% |
| Time to Breakeven | 599 days | 464 days |
| 2020 Covid Pandemic | ||
| % Loss | -28.8% | -33.9% |
| % Gain to Breakeven | 40.4% | 51.3% |
| Time to Breakeven | 116 days | 148 days |
| 2018 Correction | ||
| % Loss | -15.8% | -19.8% |
| % Gain to Breakeven | 18.8% | 24.7% |
| Time to Breakeven | 326 days | 120 days |
| 2008 Global Financial Crisis | ||
| % Loss | -40.6% | -56.8% |
| % Gain to Breakeven | 68.3% | 131.3% |
| Time to Breakeven | 1,100 days | 1,480 days |
Compare to VRTX, ALPS, DFTX, EIKN, GENB
In The Past
SPDR Select Sector Fund's stock fell -16.1% during the 2022 Inflation Shock from a high on 4/8/2022. A -16.1% loss requires a 19.1% gain to breakeven.
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About enGene Therapeutics (ENGN)
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Like Moderna or BioNTech, but applying genetic technology to develop gene-based treatments for cancer rather than vaccines.
The Tesla of gene therapy delivery, focused on developing a novel non-viral method to get genetic instructions into cancer cells.
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- EG-70: A non-viral gene therapy designed to deliver interferon alpha 2b (IFNα2b) DNA directly into the bladder for the treatment of high-risk non-muscle invasive bladder cancer (NMIBC) unresponsive to BCG.
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enGene Therapeutics (ENGN) is a clinical-stage biotechnology company focused on developing gene therapies for oncology and immunology. As a company in the research and development phase, enGene Therapeutics does not currently have major customers in the traditional sense of selling products or services to other companies or individuals.
Their primary activities involve advancing their pipeline of drug candidates through preclinical and clinical trials. Revenue generation at this stage typically comes from financing activities (e.g., equity investments), grants, and potential future collaborations or licensing agreements with larger pharmaceutical companies, rather than from direct sales of commercialized products.
Therefore, enGene Therapeutics does not have identifiable major customers at this time.
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Ron Cooper, Chief Executive OfficerRon Cooper has served as enGene Therapeutics' CEO and a member of its Board of Directors since July 2024. Previously, Mr. Cooper was President and Chief Executive Officer of Albireo Pharma, a fully integrated global commercial biopharmaceutical company that was acquired by Ipsen for up to $1.2 billion in March 2023. While at Albireo Pharma, he took the company public, created a new corporate strategy, guided Bylvay® through three Phase III programs, regulatory approvals, and a global commercial launch, and raised over $850 million of capital. Earlier in his career, Mr. Cooper spent nearly 30 years at Bristol-Myers Squibb (BMS) in various roles, most recently as President, Europe, where he played a leadership role in several successful product launches. He currently serves as Chairman of the Board for C4 Therapeutics and a member of the Board of Directors of Generation Bio.
Ryan Daws, Chief Financial Officer
Ryan Daws has served as enGene's Chief Financial Officer and Head of Business Development since November 27, 2023. Prior to joining enGene, Mr. Daws was Chief Financial Officer and Head of Business Development at Obsidian Therapeutics, Inc. from July 2019 to November 2023. From June 2017 to March 2019, he was a Managing Director in the Healthcare Investment Banking Group at Robert W. Baird & Co., focusing on life sciences companies. Mr. Daws also previously served as Chief Financial Officer and Head of Business Development at Concert Pharmaceuticals, Inc. from January 2014 to June 2017. He spent nearly 15 years originating and executing equity and mergers and acquisitions transactions in the life sciences sector at Cowen and Company, LLC and Stifel, Nicolaus & Co Inc.
Anthony T. Cheung, PhD, Co-Founder & Chief Scientific Officer
Anthony T. Cheung is a Co-Founder and the Chief Scientific Officer of enGene Therapeutics.
Matthew Boyd, Chief Regulatory Officer
Matthew Boyd was promoted to Chief Regulatory Officer in July 2025, having previously served as Senior Vice President, Regulatory Affairs. He has over 25 years of regulatory experience and has led the submission of numerous drug applications, including the approval of Bylvay for a rare pediatric liver disease while at Albireo Pharma.
Jill Buck, Chief Development Officer
Jill Buck was promoted to Chief Development Officer in July 2025, from her previous role as Senior Vice President, Clinical Development Operations. She has more than 25 years of global drug development experience across multiple therapeutic areas.
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Key Risks to enGene Therapeutics (ENGN)
- High Dependence on Lead Product Candidate: enGene Therapeutics' business success is highly dependent on the successful clinical development, regulatory approval, and commercialization of its lead product candidate, detalimogene voraplasmid (previously EG-70), for non-muscle invasive bladder cancer. The investment thesis for enGene "hinges on positive LEGEND trial results", and its pipeline is "focused almost entirely on one catalyst". Failure of this single asset would significantly impact the company's prospects.
- Inability to Achieve Profitability and Significant Cash Burn: enGene is a clinical-stage biotechnology company that has consistently incurred net losses since its inception and has not generated any revenue from product sales to date. The company is not forecast to become profitable over the next three years, and its ongoing research and development expenses are expected to increase, leading to substantial ongoing cash burn. This poses significant financial sustainability risks.
- Clinical Development, Regulatory, and Market Access Challenges: As a biotechnology company, enGene faces inherent operational challenges in clinical development, including the rigorous demands of clinical trials and the complex regulatory landscape for gene therapies. Obtaining positive trial data and securing regulatory approval on anticipated timelines are critical. Beyond approval, the company also faces risks related to competition, reimbursement challenges, and pricing pressures for gene therapies in the market.
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enGene Therapeutics (Nasdaq: ENGN) focuses on genetic medicines, with its primary product being detalimogene voraplasmid (formerly EG-70). This therapy targets high-risk, Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ (CIS).
The addressable market for high-risk non-muscle invasive bladder cancer (NMIBC) in the 7MM (United States, Germany, France, Italy, Spain, United Kingdom, and Japan) was approximately USD 1.60 billion in 2023. This segment is directly relevant to enGene's lead product. While the broader non-muscle invasive bladder cancer (NMIBC) market in these seven major markets was estimated to be around USD 3 billion in 2025, with the United States accounting for nearly 65% of that market, enGene's therapy specifically targets the high-risk, BCG-unresponsive population.
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enGene Therapeutics (Nasdaq: ENGN) is a clinical-stage biotechnology company focused on developing genetic medicines, primarily utilizing its proprietary Dually Derivatized Oligochitosan (DDX) platform for localized delivery of therapeutics to mucosal tissues and other organs.
The company's future revenue growth over the next 2-3 years is expected to be driven by the following factors:
- Regulatory Approval and Commercial Launch of Detalimogene: enGene's lead product candidate, detalimogene voraplasmid (also known as EG-70), for high-risk, Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ (CIS), is a key revenue driver. The company plans a Biologics License Application (BLA) submission for detalimogene in the second half of 2026, with a potential approval anticipated in 2027. This represents the company's first potential commercial product and a significant entry into the NMIBC market.
- Market Penetration and Adoption of Detalimogene: Following potential approval, a primary driver will be the successful market penetration and adoption of detalimogene within its initial indication of high-risk, BCG-unresponsive NMIBC with CIS. enGene believes detalimogene has the potential to become a "first choice therapy" in this patient population, which has a high clinical burden and unmet medical needs.
- Expansion of Detalimogene's Label or Use Cases: Beyond its initial indication, enGene anticipates that detalimogene's profile could support its potential for first-line use in patients with high-risk, BCG-unresponsive NMIBC with CIS. The company's CEO has also suggested that the broader bladder cancer market is projected to grow significantly with the introduction of new products, implying potential for expanded applications or use in earlier lines of therapy, which could further drive revenue within the 2-3 year timeframe if supported by additional data and regulatory approvals.
- Advancement and Partnerships for DDX Platform-Derived Candidates: enGene's proprietary DDX platform is designed for delivering genetic medicines to various mucosal tissues and organs, including genitourinary cancers and the lung. While specific new product launches from the platform might extend beyond the immediate 2-3 year horizon, the advancement of other pipeline candidates utilizing this platform or strategic partnerships leveraging the DDX technology could generate upfront payments, milestone revenues, or future product sales within this timeframe.
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Share Issuance
- In November 2025, enGene Therapeutics successfully closed an underwritten public offering of its common shares and pre-funded warrants.
- This public offering resulted in net proceeds of $140.1 million.
Inbound Investments
- In October 2024, the company expected to receive CAD 60.148968 million in funding from a group of investors.
- In January 2026, the Company expanded its existing loan and security agreement with Hercules Capital, Inc.
Capital Expenditures
- While specific dollar amounts for capital expenditures are not separately detailed in available summaries, enGene Therapeutics expects its cash and marketable securities to fund operating expenses, debt obligations, and capital expenditures into the second half of 2028, following a November 2025 public offering.
- The company's cash and marketable securities as of October 31, 2024, and April 30, 2025, were anticipated to fund operating expenses, debt obligations, and capital expenditures into 2027.
- Increased research and development expenses in 2025, rising by $56.2 million compared to 2024, were primarily driven by increased manufacturing, personnel, and clinical costs related to the LEGEND trial and preparation for the planned Biologics License Application (BLA) submission.
Trade Ideas
Select ideas related to ENGN.
| Date | Ticker | Company | Category | Trade Strategy | 6M Fwd Rtn | 12M Fwd Rtn | 12M Max DD |
|---|---|---|---|---|---|---|---|
| 03312026 | PGNY | Progyny | Dip Buy | DB | FCF Yield | Low D/EDip Buy with High Free Cash Flow YieldBuying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap | 0.0% | 0.0% | 0.0% |
| 03272026 | CNC | Centene | Dip Buy | DB | FCF Yield | Low D/EDip Buy with High Free Cash Flow YieldBuying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap | 2.3% | 2.3% | -0.6% |
| 03272026 | OSCR | Oscar Health | Dip Buy | DB | FCF Yield | Low D/EDip Buy with High Free Cash Flow YieldBuying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap | 3.0% | 3.0% | -2.6% |
| 03202026 | WAT | Waters | Monopoly | MY | Getting CheaperMonopoly-Like with P/S DeclineLarge cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple | -0.4% | -0.4% | -3.3% |
| 03202026 | GILD | Gilead Sciences | Quality | Q | Momentum | UpsideQuality Stocks with Momentum and UpsideBuying quality stocks with strong momentum but still having room to run | 1.6% | 1.6% | -2.2% |
Research & Analysis
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Peer Comparisons
| Peers to compare with: |
Financials
| Median | |
|---|---|
| Name | |
| Mkt Price | 11.75 |
| Mkt Cap | 56.6 |
| Rev LTM | 0 |
| Op Inc LTM | -128 |
| FCF LTM | -104 |
| FCF 3Y Avg | -66 |
| CFO LTM | -102 |
| CFO 3Y Avg | -65 |
Growth & Margins
| Median | |
|---|---|
| Name | |
| Rev Chg LTM | 8.9% |
| Rev Chg 3Y Avg | 10.4% |
| Rev Chg Q | 9.5% |
| QoQ Delta Rev Chg LTM | 2.4% |
| Op Mgn LTM | 37.9% |
| Op Mgn 3Y Avg | 24.7% |
| QoQ Delta Op Mgn LTM | 38.7% |
| CFO/Rev LTM | 30.3% |
| CFO/Rev 3Y Avg | 20.5% |
| FCF/Rev LTM | 26.6% |
| FCF/Rev 3Y Avg | 17.0% |
Valuation
| Median | |
|---|---|
| Name | |
| Mkt Cap | 56.6 |
| P/S | 9.4 |
| P/EBIT | 10.0 |
| P/E | 12.2 |
| P/CFO | 13.0 |
| Total Yield | -10.2% |
| Dividend Yield | 0.0% |
| FCF Yield 3Y Avg | -7.4% |
| D/E | 0.0 |
| Net D/E | -0.3 |
Returns
| Median | |
|---|---|
| Name | |
| 1M Rtn | -1.7% |
| 3M Rtn | -1.1% |
| 6M Rtn | 3.6% |
| 12M Rtn | 3.6% |
| 3Y Rtn | 3.6% |
| 1M Excs Rtn | -6.8% |
| 3M Excs Rtn | -0.7% |
| 6M Excs Rtn | -2.7% |
| 12M Excs Rtn | -28.6% |
| 3Y Excs Rtn | -66.1% |
Segment Financials
Revenue by Segment| $ Mil | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|
| Developing genetic medicines to improve the lives of patients suffering from bladder cancer | 0 | 0 | ||
| Total | 0 | 0 |
| $ Mil | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|
| Developing genetic medicines to improve the lives of patients suffering from bladder cancer | -14 | |||
| Total | -14 |
| $ Mil | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|
| Developing genetic medicines to improve the lives of patients suffering from bladder cancer | 311 | 87 | 15 | |
| Total | 311 | 87 | 15 |
Price Behavior
Price Behavior
| Market Price | $7.60 | |
| Market Cap ($ Bil) | 0.5 | |
| First Trading Date | 11/01/2023 | |
| Distance from 52W High | -37.6% | |
| 50 Days | 200 Days | |
| DMA Price | $8.36 | $7.10 |
| DMA Trend | up | down |
| Distance from DMA | -9.1% | 7.1% |
| 3M | 1YR | |
| Volatility | 85.7% | 92.8% |
| Downside Capture | 0.81 | 1.09 |
| Upside Capture | 170.59 | 240.69 |
| Correlation (SPY) | 16.8% | 16.7% |
ENGN Betas & Captures as of 3/31/2026
[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
| 1M | 2M | 3M | 6M | 1Y | 3Y | |
|---|---|---|---|---|---|---|
| Beta | -0.90 | 1.02 | 0.95 | 2.11 | 0.53 | -0.24 |
| Up Beta | -3.51 | 2.05 | 0.81 | -0.65 | -0.56 | 0.45 |
| Down Beta | -2.38 | -0.34 | 0.23 | 1.55 | 0.28 | 0.05 |
| Up Capture | -321% | 12% | 71% | 481% | 362% | 21% |
| Bmk +ve Days | 7 | 16 | 27 | 65 | 139 | 424 |
| Stock +ve Days | 8 | 19 | 30 | 56 | 122 | 279 |
| Down Capture | 190% | 204% | 159% | 203% | 139% | 103% |
| Bmk -ve Days | 12 | 23 | 33 | 58 | 110 | 323 |
| Stock -ve Days | 14 | 23 | 32 | 68 | 122 | 310 |
[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
| Annualized Return | Annualized Volatility | Sharpe Ratio | Correlation with ENGN | |
|---|---|---|---|---|
| ENGN | 87.0% | 92.6% | 1.07 | - |
| Sector ETF (XLV) | 11.9% | 16.0% | 0.52 | 20.8% |
| Equity (SPY) | 24.2% | 12.9% | 1.49 | 16.8% |
| Gold (GLD) | 53.4% | 27.6% | 1.55 | 8.4% |
| Commodities (DBC) | 26.8% | 16.2% | 1.47 | -0.2% |
| Real Estate (VNQ) | 18.7% | 13.8% | 1.00 | 7.7% |
| Bitcoin (BTCUSD) | -6.8% | 42.9% | -0.05 | 12.8% |
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Based On 5-Year Data
| Annualized Return | Annualized Volatility | Sharpe Ratio | Correlation with ENGN | |
|---|---|---|---|---|
| ENGN | -17.9% | 124.8% | 0.15 | - |
| Sector ETF (XLV) | 6.6% | 14.6% | 0.27 | 8.5% |
| Equity (SPY) | 11.1% | 17.0% | 0.50 | 6.8% |
| Gold (GLD) | 22.5% | 17.8% | 1.03 | 0.3% |
| Commodities (DBC) | 11.7% | 18.8% | 0.51 | 0.3% |
| Real Estate (VNQ) | 3.9% | 18.8% | 0.11 | 1.1% |
| Bitcoin (BTCUSD) | 5.8% | 56.5% | 0.32 | 10.9% |
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Based On 10-Year Data
| Annualized Return | Annualized Volatility | Sharpe Ratio | Correlation with ENGN | |
|---|---|---|---|---|
| ENGN | -9.4% | 124.8% | 0.15 | - |
| Sector ETF (XLV) | 9.9% | 16.5% | 0.49 | 8.5% |
| Equity (SPY) | 14.0% | 17.9% | 0.67 | 6.8% |
| Gold (GLD) | 14.3% | 15.9% | 0.75 | 0.3% |
| Commodities (DBC) | 8.8% | 17.6% | 0.42 | 0.3% |
| Real Estate (VNQ) | 5.4% | 20.7% | 0.23 | 1.1% |
| Bitcoin (BTCUSD) | 67.7% | 66.9% | 1.07 | 10.9% |
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Earnings Returns History
Expand for More| Forward Returns | |||
|---|---|---|---|
| Earnings Date | 1D Returns | 5D Returns | 21D Returns |
| 3/9/2026 | -18.8% | -17.5% | -15.6% |
| 12/22/2025 | 5.1% | 2.1% | 38.8% |
| 9/11/2025 | -5.8% | 14.9% | 38.4% |
| 6/12/2025 | 0.9% | 2.2% | 9.0% |
| 3/10/2025 | -1.7% | -2.1% | -21.4% |
| 12/19/2024 | -2.2% | 7.7% | 22.3% |
| 9/10/2024 | 3.1% | 6.8% | 6.5% |
| 1/29/2024 | 4.7% | 0.5% | 98.6% |
| SUMMARY STATS | |||
| # Positive | 4 | 6 | 6 |
| # Negative | 4 | 2 | 2 |
| Median Positive | 3.9% | 4.5% | 30.4% |
| Median Negative | -4.0% | -9.8% | -18.5% |
| Max Positive | 5.1% | 14.9% | 98.6% |
| Max Negative | -18.8% | -17.5% | -21.4% |
SEC Filings
Expand for More| Report Date | Filing Date | Filing |
|---|---|---|
| 01/31/2026 | 03/09/2026 | 10-Q |
| 10/31/2025 | 12/22/2025 | 10-K |
| 07/31/2025 | 09/11/2025 | 10-Q |
| 04/30/2025 | 06/12/2025 | 10-Q |
| 01/31/2025 | 03/10/2025 | 10-Q |
| 10/31/2024 | 12/19/2024 | 10-K |
| 07/31/2024 | 09/10/2024 | 10-Q |
| 04/30/2024 | 06/14/2024 | 10-Q |
| 01/31/2024 | 03/11/2024 | 10-Q |
| 10/31/2023 | 01/29/2024 | 10-K |
| 07/31/2023 | 09/26/2023 | S-4/A |
| 04/30/2023 | 08/09/2023 | S-4 |
Recent Forward Guidance [BETA]
Latest: Q1 2026 Earnings Reported 3/9/2026
| Forward Guidance | Guidance Change | ||||||
|---|---|---|---|---|---|---|---|
| Metric | Low | Mid | High | % Chg | % Delta | Change | Prior |
| 2028 Cash Runway | 2,028 | ||||||
Prior: Q4 2025 Earnings Reported 12/22/2025
| Forward Guidance | Guidance Change | ||||||
|---|---|---|---|---|---|---|---|
| Metric | Low | Mid | High | % Chg | % Delta | Change | Prior |
| 2026 BLA Submission | |||||||
| 2026 LEGEND Trial Data Update | |||||||
| 2027 Cash Runway | 2,027 | ||||||
Industry Resources
External Quote Links
| Y Finance | Barrons |
| TradingView | Morningstar |
| SeekingAlpha | ValueLine |
| Motley Fool | Robinhood |
| CNBC | Etrade |
| MarketWatch | Unusual Whales |
| YCharts | Perplexity Finance |
| FinViz |
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