Market Movers | Winners: ACXP, SAFX, SXTP | Losers: CODX, QNTM, KITT

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On Wednesday, March 11, a calm session left the S&P 500 falling 0.08%, the Dow 30 falling 0.61%, and the Nasdaq 100 remaining flat nearly unchanged. Yet under the surface, there was more activity in specific names.
 

Trefis: RUA Stock Insights

List of Market Winners

The following table shows the list of 10 stocks that generated the highest returns on the last trading day:
 

# Ticker Company Name 1-D
Returns
YTD
Returns
1 ACXP Acurx Pharmaceuticals 107.9% 142.2%
2 SAFX XCF Global 74.5% 82.5%
3 SXTP 60 Degrees Pharmaceuticals 71.3% 58.4%
4 ASNS Actelis Networks 47.6% 12.2%
5 AMCI AMC Robotics 35.0% 19.5%
6 BODI Beachbody 31.0% 5.3%
7 OCGN Ocugen 29.9% 70.4%
8 POLA Polar Power 26.8% 16.2%
9 CVGI Commercial Vehicle 25.3% 41.0%
10 SBNY Signature Bank 25.0% -35.3%

 
List of Market Losers

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On the other hand, the following table shows the list of 10 stocks that generated the lowest returns:
 

# Ticker Company Name 1-D
Returns
YTD
Returns
1 CODX Co-Diagnostics -26.4% -35.9%
2 QNTM Quantum BioPharma -25.0% -71.2%
3 KITT Nauticus Robotics -23.2% 2.0%
4 CLIR ClearSign Technologies -21.6% -19.5%
5 FCUV Focus Universal -20.7% -45.3%
6 EZRA Reliance Global -18.6% -23.6%
7 INKT MiNK Therapeutics -17.2% 0.3%
8 PHGE BiomX -16.8% 233.7%
9 KOS Kosmos Energy -16.6% 121.5%
10 FWRD Forward Air -16.6% -26.4%

 
Why does this matter? Significant stock moves – up or down – deserve your attention. Sharp declines in fundamentally strong names can offer smart buying opportunities. And when momentum aligns with solid fundamentals, riding the trend can be highly rewarding.

Smart investing isn’t about stock picking or prediction, it’s about asset allocation. See how Trefis’ Boston-based wealth management partner does it. It has included the High Quality Portfolio as part of its asset allocation strategy.

Movers – Last One Week

Analysing over the last one week (5 trading days), a broad-based downturn weighed on the S&P 500 falling 1.36%, the Dow 30 falling 2.71%, and the Nasdaq 100 falling 0.51%. Most stocks traded lower, with limited bright spots.
 
List of 1-Week Market Winners

The following table shows the list of 10 stocks that generated the highest returns over the last week:
 

# Ticker Company Name 1-W
Returns
YTD
Returns
1 MMED Minimed 85852.4% 85852.4%
2 CAST FreeCast 29529.6% 29529.6%
3 TVGN Tevogen Bio 3917.2% -54.8%
4 KIDZ Classover 2761.6% -69.1%
5 DCOY Decoy Therapeutics Inc. 1096.3% 1.0%
6 RVPH Reviva Pharmaceuticals 1050.2% -49.6%
7 ADTX Aditxt 463.6% -59.9%
8 ELAB PMGC 323.8% -87.5%
9 ACXP Acurx Pharmaceuticals 296.7% 142.2%
10 ANTX AN2 Therapeutics 279.9% 346.5%

 
List of 1-Week Market Losers

Similarly, the following table shows the 10 stocks that were at the bottom in terms of returns:
 

# Ticker Company Name 1-W
Returns
YTD
Returns
1 ALUR Allurion Technologies -65.7% -78.8%
2 MDCX Medicus Pharma -64.8% -68.3%
3 CLDI Calidi Biotherapeutics -56.5% -70.4%
4 RBOT Vicarious Surgical -53.3% -80.6%
5 LNAI Lunai Bioworks -50.1% -78.4%
6 OWLT Owlet -49.3% -62.8%
7 ARQ Arq -49.1% -45.6%
8 CMCT Creative Media & Community Trust -45.9% -64.7%
9 QNTM Quantum BioPharma -44.7% -71.2%
10 CD Chaince Digital -38.0% -0.6%

 
Movers – Last One Month

On a slightly wider timeline over the last one month, selling pressure hit the S&P 500 falling 2.71%, the Dow 30 falling 5.42%, and the Nasdaq 100 falling 1.20%. Declines were common, though some stocks held steady.
 
List of 1-Month Market Winners

The following table shows the 10 stocks that generated the maximum returns over the last one month:
 

# Ticker Company Name 1-M
Returns
YTD
Returns
1 MMED Minimed 85852.4% 85852.4%
2 CAST FreeCast 29529.6% 29529.6%
3 ATPC Agape ATP 8427.6% -21.7%
4 HCTI Healthcare Triangle 1940.0% -91.9%
5 ANY Sphere 3D 847.1% -45.9%
6 BATL Battalion Oil 582.5% 1621.2%
7 EDSA Edesa Biotech 491.1% 366.2%
8 ANTX AN2 Therapeutics 371.3% 346.5%
9 RXT Rackspace Technology 361.0% 97.8%
10 SGN Signing Day Sports 297.3% -23.9%

 
List of 1-Month Market Losers

In the same period, these 10 stocks were at the bottom in terms of returns:
 

# Ticker Company Name 1-M
Returns
YTD
Returns
1 RPGL Republic Power -99.4% -99.5%
2 ROC Rank One Computing -92.4% -92.4%
3 OBAI Our Bond -87.8% -93.9%
4 AREB American Rebel -86.5% -99.0%
5 NUCL Eagle Nuclear Energy -84.3% -84.3%
6 LIMN Liminatus Pharma -82.4% -58.2%
7 ARTC Art Technology Acquisition -79.8% -79.8%
8 RNA Atrium Therapeutics -79.7% -79.5%
9 RBOT Vicarious Surgical -79.5% -80.6%
10 SHAZ SharonAI -78.6% -78.6%

 

Picking winners on a consistent basis is not an easy task – especially given the volatility associated with a single stock. Instead, the Trefis High Quality (HQ) Portfolio, with a collection of 30 stocks, has a track record of comfortably outperforming its benchmark that includes all 3 — the S&P 500, S&P mid-cap, and Russell 2000 indices. Why is that? As a group, HQ Portfolio stocks provided better returns with less risk versus the benchmark index; less of a roller-coaster ride, as evident in HQ Portfolio performance metrics.