Market Movers | Winners: MMED, TVGN, PRSO | Losers: CLDI, IMG, MDCX
On Friday, March 6, the broader market was quiet, with the S&P 500 remaining flat, the Dow 30 remaining flat, and the Nasdaq 100 remaining flat. Despite the subdued index movement, stock-level volatility remained noticeable.

List of Market Winners
The following table shows the list of 10 stocks that generated the highest returns on the last trading day:
| # | Ticker | Company Name | 1-D Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | MMED | Minimed | 87947.6% | 87947.6% |
| 2 | TVGN | Tevogen Bio | 4613.1% | -55.8% |
| 3 | PRSO | Peraso | 151.5% | 134.5% |
| 4 | EDSA | Edesa Biotech | 80.6% | 359.2% |
| 5 | ANTX | AN2 Therapeutics | 66.7% | 150.0% |
| 6 | DAWN | Day One Biopharmaceuticals | 65.9% | 127.5% |
| 7 | SEV | Aptera Motors | 39.0% | -23.5% |
| 8 | COHN | Cohen | 36.2% | -16.0% |
| 9 | QURE | uniQure | 34.0% | -40.4% |
| 10 | AIFF | Firefly Neuroscience | 30.3% | 111.4% |
List of Market Losers
On the other hand, the following table shows the list of 10 stocks that generated the lowest returns:
| # | Ticker | Company Name | 1-D Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | CLDI | Calidi Biotherapeutics | -53.1% | -69.2% |
| 2 | IMG | CIMG | -52.8% | -90.3% |
| 3 | MDCX | Medicus Pharma | -42.9% | -74.7% |
| 4 | CCHH | CCH | -39.5% | 21.8% |
| 5 | OWLT | Owlet | -38.2% | -55.2% |
| 6 | SKYQ | Sky Quarry | -37.7% | 54.4% |
| 7 | LNAI | Lunai Bioworks | -35.8% | -73.7% |
| 8 | PROF | Profound Medical | -29.1% | -32.5% |
| 9 | NVVE | Nuvve | -25.6% | -63.4% |
| 10 | GPRO | GoPro | -24.0% | -46.1% |
Why does this matter? Significant stock moves – up or down – deserve your attention. Sharp declines in fundamentally strong names can offer smart buying opportunities. And when momentum aligns with solid fundamentals, riding the trend can be highly rewarding.
Stock picking can fail no matter how good the strategy is. The Trefis High Quality Portfolio turns single-stock insights into a robust market-beating portfolio strategy.
Movers – Last One Week
Analysing over the last one week (5 trading days), markets declined across the board, with the S&P 500 falling 2.06%, the Dow 30 falling 2.87%, and the Nasdaq 100 falling 1.40%. Although broad pressure was felt, a few stocks managed to outperform.
List of 1-Week Market Winners
The following table shows the list of 10 stocks that generated the highest returns over the last week:
| # | Ticker | Company Name | 1-W Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | MMED | Minimed | 87947.6% | 87947.6% |
| 2 | TVGN | Tevogen Bio | 2666.8% | -55.8% |
| 3 | MOBX | Mobix Labs | 530.3% | 289.1% |
| 4 | TPET | Trio Petroleum | 359.5% | 143.1% |
| 5 | BATL | Battalion Oil | 305.1% | 1878.8% |
| 6 | EDSA | Edesa Biotech | 196.4% | 359.2% |
| 7 | AIFF | Firefly Neuroscience | 165.3% | 111.4% |
| 8 | ANTX | AN2 Therapeutics | 159.1% | 150.0% |
| 9 | PRSO | Peraso | 141.3% | 134.5% |
| 10 | DAWN | Day One Biopharmaceuticals | 100.0% | 127.5% |
List of 1-Week Market Losers
Similarly, the following table shows the 10 stocks that were at the bottom in terms of returns:
| # | Ticker | Company Name | 1-W Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | IMG | CIMG | -78.1% | -90.3% |
| 2 | MDCX | Medicus Pharma | -74.7% | -74.7% |
| 3 | WORX | SCWorx | -63.5% | -34.1% |
| 4 | CLDI | Calidi Biotherapeutics | -54.6% | -69.2% |
| 5 | AARD | Aardvark Therapeutics | -53.2% | -55.4% |
| 6 | AGIG | Abundia Global Impact | -51.2% | 3.0% |
| 7 | ALUR | Allurion Technologies | -42.6% | -45.4% |
| 8 | FTCI | FTC Solar | -42.5% | -61.9% |
| 9 | CSTE | Caesarstone | -41.5% | -56.9% |
| 10 | ALBT | Avalon Globocare | -38.5% | -23.6% |
Movers – Last One Month
On a slightly wider timeline over the last one month, markets were split, as the S&P 500 falling 0.86%, the Dow 30 falling 2.88%, and the Nasdaq 100 rising 0.38% moved in different directions. Similar variation was seen across individual stocks.
List of 1-Month Market Winners
The following table shows the 10 stocks that generated the maximum returns over the last one month:
| # | Ticker | Company Name | 1-M Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | MMED | Minimed | 87947.6% | 87947.6% |
| 2 | ATPC | Agape ATP | 2507.1% | -58.9% |
| 3 | RLYB | Rallybio | 1796.7% | 98.8% |
| 4 | UGRO | Urban-gro | 1564.4% | -65.3% |
| 5 | ASST | Strive | 1368.6% | -41.1% |
| 6 | ADIL | Adial Pharmaceuticals | 1067.1% | -66.7% |
| 7 | HCTI | Healthcare Triangle | 1059.8% | -92.9% |
| 8 | PFSA | Profusa | 933.9% | -88.7% |
| 9 | BATL | Battalion Oil | 747.0% | 1878.8% |
| 10 | ANY | Sphere 3D | 716.0% | -40.5% |
List of 1-Month Market Losers
In the same period, these 10 stocks were at the bottom in terms of returns:
| # | Ticker | Company Name | 1-M Returns |
YTD Returns |
|---|---|---|---|---|
| 1 | RPGL | Republic Power | -99.5% | -99.4% |
| 2 | OBAI | Our Bond | -94.5% | -94.5% |
| 3 | ROC | Rank One Computing | -92.0% | -92.0% |
| 4 | AREB | American Rebel | -88.3% | -98.9% |
| 5 | PLYX | Polaryx Therapeutics | -87.8% | -92.2% |
| 6 | NUCL | Eagle Nuclear Energy | -86.0% | -86.0% |
| 7 | LIMN | Liminatus Pharma | -83.8% | -61.9% |
| 8 | IMG | CIMG | -83.6% | -90.3% |
| 9 | ARTC | Art Technology Acquisition | -79.9% | -79.9% |
| 10 | GOSS | Gossamer Bio | -79.6% | -83.8% |
Picking winners on a consistent basis is not an easy task – especially given the volatility associated with a single stock. Instead, the Trefis High Quality (HQ) Portfolio, with a collection of 30 stocks, has a track record of comfortably outperforming its benchmark that includes all 3 — the S&P 500, S&P mid-cap, and Russell 2000 indices. Why is that? As a group, HQ Portfolio stocks provided better returns with less risk versus the benchmark index; less of a roller-coaster ride, as evident in HQ Portfolio performance metrics.