Market Movers | Winners: ENVB, CODX, SOHO | Losers: NTLA, MAMK, IRBT

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On Monday, October 27, all major indices rose in unison — the S&P 500 rising 1.23%, the Dow 30 rising 0.71%, and the Nasdaq 100 rising 1.83%. The strength was widespread, though a few names underperformed.
 

List of Market Winners

The following table shows the list of 10 stocks that generated the highest returns on the last trading day:
 

# Ticker Company Name 1-D
Returns
YTD
Returns
1 ENVB Enveric Biosciences 1074.6% 37.2%
2 CODX Co-Diagnostics 259.3% 68.0%
3 SOHO Sotherly Hotels 141.5% 130.8%
4 CLIK Click 68.4% -70.7%
5 ASST Strive 49.1% 234.4%
6 RNA Avidity Biosciences 42.4% 140.7%
7 DYN Dyne Therapeutics 41.2% 2.6%
8 DTCK Davis Commodities 35.7% 49.7%
9 ZBIO Zenas BioPharma 33.1% 288.3%
10 BKYI BIO-key International 32.5% -40.4%

 
List of Market Losers

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On the other hand, the following table shows the list of 10 stocks that generated the lowest returns:
 

# Ticker Company Name 1-D
Returns
YTD
Returns
1 NTLA Intellia Therapeutics -42.2% 26.8%
2 MAMK MaxsMaking -35.0%  
3 IRBT iRobot -33.9% -52.4%
4 FPAY FlexShopper -33.8% -99.4%
5 SCNX Scienture -29.3% -81.7%
6 WGRX Wellgistics Health -28.7%  
7 NEUP Neuphoria Therapeutics -27.4% 32.1%
8 OGN Organon -22.9% -51.6%
9 AREB American Rebel -22.3% -99.8%
10 PRE Prenetics Global -22.0% 125.5%

 
Why does this matter? Significant stock moves – up or down – deserve your attention. Sharp declines in fundamentally strong names can offer smart buying opportunities. And when momentum aligns with solid fundamentals, riding the trend can be highly rewarding.

If you seek an upside with less volatility than holding an individual stock, consider the Trefis High Quality Portfolio (HQ). HQ has outperformed its benchmark — a combination of S&P 500, Russell, and S&P midcap index — and achieved returns exceeding 91% since its inception. Risk management is key — consider what the long-term portfolio performance could be if you blended 10% commodities, 10% gold, and 2% crypto with HQ’s performance metrics.

Movers – Last One Week

Analysing over the last one week (5 trading days), a market-wide surge lifted the S&P 500 rising 2.08%, the Dow 30 rising 1.79%, and the Nasdaq 100 rising 2.71%. Gains were broad-based, though not every stock joined the rally.
 
List of 1-Week Market Winners

The following table shows the list of 10 stocks that generated the highest returns over the last week:
 

# Ticker Company Name 1-W
Returns
YTD
Returns
1 WOK WORK Medical Technology 9621.4% -99.3%
2 GNPX Genprex 3025.0% -79.5%
3 ENVB Enveric Biosciences 934.3% 37.2%
4 SMX SMX 403.4% -99.9%
5 CODX Co-Diagnostics 264.4% 68.0%
6 SOHO Sotherly Hotels 146.0% 130.8%
7 SCNX Scienture 118.2% -81.7%
8 DTCK Davis Commodities 99.9% 49.7%
9 WGRX Wellgistics Health 90.9%  
10 ASST Strive 89.8% 234.4%

 
List of 1-Week Market Losers

Similarly, the following table shows the 10 stocks that were at the bottom in terms of returns:
 

# Ticker Company Name 1-W
Returns
YTD
Returns
1 FPAY FlexShopper -95.4% -99.4%
2 NEUP Neuphoria Therapeutics -70.6% 32.1%
3 PMI Picard Medical -59.1% 7439.7%
4 ALEC Alector -54.7% -20.6%
5 ARCT Arcturus Therapeutics -50.8% -37.6%
6 CYCU Cycurion -47.3% -98.8%
7 NTLA Intellia Therapeutics -47.1% 26.8%
8 SLE Super League Enterprise -46.5% -92.5%
9 AMBI Ambipar Emergency Response -46.3% -88.6%
10 ADTX Aditxt -43.5% -99.6%

 
Movers – Last One Month

On a slightly wider timeline over the last one month, a market-wide surge lifted the S&P 500 rising 3.48%, the Dow 30 rising 2.81%, and the Nasdaq 100 rising 5.38%. Gains were broad-based, though not every stock joined the rally.
 
List of 1-Month Market Winners

The following table shows the 10 stocks that generated the maximum returns over the last one month:
 

# Ticker Company Name 1-M
Returns
YTD
Returns
1 RAYA Erayak Power Solution 10529.1% -98.4%
2 YAAS Youxin Technology 3664.9% -99.2%
3 WOLF Wolfspeed 2452.9% 363.8%
4 SPRB Spruce Biosciences 1487.4% -94.8%
5 ENVB Enveric Biosciences 1117.2% 37.2%
6 POAI Predictive Oncology 1099.8% -24.4%
7 YHGJ Yunhong Green CTI 976.1% 4.6%
8 RANI Rani Therapeutics 270.8% 29.9%
9 PRAX Praxis Precision Medicines 254.6% 141.6%
10 NUAI New Era Energy & Digital 240.8%  

 
List of 1-Month Market Losers

In the same period, these 10 stocks were at the bottom in terms of returns:
 

# Ticker Company Name 1-M
Returns
YTD
Returns
1 FPAY FlexShopper -98.6% -99.4%
2 YDKG Yueda Digital -98.1%  
3 YYAI Airwa -97.0% -94.3%
4 BINI Bollinger Innovations -96.0% -100.0%
5 KALA Kala Bio -95.8% -88.4%
6 WTO UTime -94.9% -98.3%
7 DKI Darkiris -94.3%  
8 AREB American Rebel -93.5% -99.8%
9 TDIC Dreamland -92.6%  
10 MSGY Masonglory -92.2%  

 

Picking winners on a consistent basis is not an easy task – especially given the volatility associated with a single stock. Instead, the Trefis High Quality (HQ) Portfolio, with a collection of 30 stocks, has a track record of comfortably outperforming its benchmark that includes all 3 — the S&P 500, S&P mid-cap, and Russell 2000 indices. Why is that? As a group, HQ Portfolio stocks provided better returns with less risk versus the benchmark index; less of a roller-coaster ride, as evident in HQ Portfolio performance metrics.