Geron (GERN)


Market Price (8/25/2026): $1.525 | Market Cap: $1.0 BilSector: Health Care | Industry: Biotechnology

Geron (GERN)


Market Price (8/25/2026): $1.525
Market Cap: $1.0 Bil
Sector: Health Care
Industry: Biotechnology

Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.

0

Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -18%

Megatrend and thematic drivers
Megatrends include Precision Medicine, and Aging Population & Chronic Disease. Themes include Targeted Therapies, Biopharmaceutical R&D, Show more.

Weak multi-year price returns
2Y Excs Rtn is -102%, 3Y Excs Rtn is -116%

Meaningful short interest
Short Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 11%

Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -35 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -17%

Significant share based compensation
SBC/Rev LTMShare Based Compensation / Revenue (Sales), Last Twelve Months (LTM) is 11%

Not cash flow generative
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -56%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -56%

Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -11%

Key risks
GERN key risks include [1] its heavy dependence on a single product, Show more.

0 Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -18%
1 Megatrend and thematic drivers
Megatrends include Precision Medicine, and Aging Population & Chronic Disease. Themes include Targeted Therapies, Biopharmaceutical R&D, Show more.
2 Weak multi-year price returns
2Y Excs Rtn is -102%, 3Y Excs Rtn is -116%
3 Meaningful short interest
Short Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 11%
4 Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -35 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -17%
5 Significant share based compensation
SBC/Rev LTMShare Based Compensation / Revenue (Sales), Last Twelve Months (LTM) is 11%
6 Not cash flow generative
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -56%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -56%
7 Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -11%
8 Key risks
GERN key risks include [1] its heavy dependence on a single product, Show more.

GERN in ETFs

Weight = GERN's share of each fund

VTI0.00%
ITOT0.00%
IWM0.03%
XBI0.31%
IBB0.07%
IWO0.05%
VTWO0.02%
SCHA0.02%
+4 more covered ETFs

Valuation & Metrics

Price Chart

Why The Stock Moved

Qualitative Assessment

AI Analysis | Feedback

Updated on 8/13/2026

Geron (GERN) stock has remained largely at the same level since 4/30/2026 because of the following key factors:

1. Mixed Fiscal Q2 2026 Financial Results Presented a Balanced Outlook.

Geron (which operates on a calendar fiscal year, with its fiscal Q2 2026 ending in June 2026) reported its second quarter 2026 financial results on August 5, 2026, which presented a mixed picture, leading to a consolidation in stock movement. The company exceeded revenue expectations with RYTELO net product revenue reaching $57.5 million, representing a 17% increase year-over-year and an 11% sequential rise. This commercial momentum was further bolstered by Geron raising its full-year 2026 RYTELO net product revenue guidance to the mid-to-high end of $220 million to $240 million. However, these positive indicators were significantly offset by a wider-than-anticipated net loss of $0.02 per share, missing the consensus estimate by $0.01. Additionally, total operating expenses climbed 16% year-over-year to $70.0 million, highlighting persistent challenges in achieving profitability despite growing product sales. This combination of strong revenue growth and continued losses resulted in a balanced investor sentiment, preventing a strong directional trend in the stock.

2. Postponement of Key Clinical Trial Results Delayed Potential Catalysts.

The stock's sideways movement was influenced by the absence of imminent, significant clinical catalysts. Specifically, the postponement of the pivotal Phase 3 IMpactMF trial results for relapsed/refractory myelofibrosis until the second half of 2026 meant a lack of near-term value-creating events for investors to anticipate. While Geron's RYTELO continues its commercialization efforts, the delayed data from its pipeline effectively removed a potential driver for substantial stock appreciation or depreciation during the specified period, contributing to the stock remaining largely at the same level.

Show more
Updated on 8/13/2026

Geron (GERN) stock has remained largely at the same level since 4/30/2026 because of the following key factors:

1. Mixed Fiscal Q2 2026 Financial Results Presented a Balanced Outlook.

Geron (which operates on a calendar fiscal year, with its fiscal Q2 2026 ending in June 2026) reported its second quarter 2026 financial results on August 5, 2026, which presented a mixed picture, leading to a consolidation in stock movement. The company exceeded revenue expectations with RYTELO net product revenue reaching $57.5 million, representing a 17% increase year-over-year and an 11% sequential rise. This commercial momentum was further bolstered by Geron raising its full-year 2026 RYTELO net product revenue guidance to the mid-to-high end of $220 million to $240 million. However, these positive indicators were significantly offset by a wider-than-anticipated net loss of $0.02 per share, missing the consensus estimate by $0.01. Additionally, total operating expenses climbed 16% year-over-year to $70.0 million, highlighting persistent challenges in achieving profitability despite growing product sales. This combination of strong revenue growth and continued losses resulted in a balanced investor sentiment, preventing a strong directional trend in the stock.

2. Postponement of Key Clinical Trial Results Delayed Potential Catalysts.

The stock's sideways movement was influenced by the absence of imminent, significant clinical catalysts. Specifically, the postponement of the pivotal Phase 3 IMpactMF trial results for relapsed/refractory myelofibrosis until the second half of 2026 meant a lack of near-term value-creating events for investors to anticipate. While Geron's RYTELO continues its commercialization efforts, the delayed data from its pipeline effectively removed a potential driver for substantial stock appreciation or depreciation during the specified period, contributing to the stock remaining largely at the same level.

3. Balanced Analyst Sentiment and Lingering Valuation Concerns.

Analyst opinions and valuation metrics also contributed to the stable, rather than trending, stock performance. While several analysts maintained "Buy" ratings with a median 12-month price target of $4.00, implying a significant potential upside of over 170% from recent trading prices, the overall consensus rating for Geron remained "Hold" during this period. This mixed sentiment was further complicated by a downgrade from Weiss Ratings to "sell (e+)" on July 24, 2026. Compounding this, Geron's Price-to-Sales (P/S) ratio stood at 4.57, considerably below its historical median of approximately 414.2x, indicating a cautious market stance regarding the company's long-term growth prospects and profitability in the highly competitive biotechnology sector, thus tempering aggressive buying interest.

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Stock Movement Drivers

Fundamental Drivers

The -1.3% change in GERN stock from 4/30/2026 to 8/24/2026 was primarily driven by a -10.8% change in the company's P/S Multiple.
(LTM values as of)43020268242026Change
Stock Price ($)1.541.52-1.3%
Change Contribution By: 
Total Revenues ($ Mil)18420511.2%
P/S Multiple5.65.0-10.8%
Shares Outstanding (Mil)667671-0.5%
Cumulative Contribution-1.3%

LTM = Last Twelve Months as of date shown

Market Drivers

4/30/2026 to 8/24/2026
ReturnCorrelation
GERN-1.3% 
Market (SPY)6.2%3.4%
Sector (XLV)19.7%22.9%

Fundamental Drivers

The 10.9% change in GERN stock from 1/31/2026 to 8/24/2026 was primarily driven by a 11.5% change in the company's Total Revenues ($ Mil).
(LTM values as of)13120268242026Change
Stock Price ($)1.371.5210.9%
Change Contribution By: 
Total Revenues ($ Mil)18320511.5%
P/S Multiple5.05.00.0%
Shares Outstanding (Mil)667671-0.5%
Cumulative Contribution10.9%

LTM = Last Twelve Months as of date shown

Market Drivers

1/31/2026 to 8/24/2026
ReturnCorrelation
GERN10.9% 
Market (SPY)10.6%23.1%
Sector (XLV)13.4%28.6%

Fundamental Drivers

The 32.2% change in GERN stock from 7/31/2025 to 8/24/2026 was primarily driven by a 75.9% change in the company's Total Revenues ($ Mil).
(LTM values as of)73120258242026Change
Stock Price ($)1.151.5232.2%
Change Contribution By: 
Total Revenues ($ Mil)11620575.9%
P/S Multiple6.65.0-24.3%
Shares Outstanding (Mil)666671-0.7%
Cumulative Contribution32.2%

LTM = Last Twelve Months as of date shown

Market Drivers

7/31/2025 to 8/24/2026
ReturnCorrelation
GERN32.2% 
Market (SPY)21.8%25.1%
Sector (XLV)35.7%29.5%

Fundamental Drivers

The -53.1% change in GERN stock from 7/31/2023 to 8/24/2026 was primarily driven by a -99.9% change in the company's P/S Multiple.
(LTM values as of)73120238242026Change
Stock Price ($)3.241.52-53.1%
Change Contribution By: 
Total Revenues ($ Mil)020541308.7%
P/S Multiple3,570.95.0-99.9%
Shares Outstanding (Mil)544671-18.8%
Cumulative Contribution-53.1%

LTM = Last Twelve Months as of date shown

Market Drivers

7/31/2023 to 8/24/2026
ReturnCorrelation
GERN-53.1% 
Market (SPY)72.7%19.5%
Sector (XLV)36.3%21.2%

Return vs. Risk

Price Returns Compared

 202120222023202420252026Total [1]
Returns
GERN Return-23%98%-13%68%-63%15%-4%
Peers Return10%19%-7%11%28%27%121%
S&P 500 Return27%-19%24%23%16%12%104%

Monthly Win Rates [3]
GERN Win Rate42%58%50%58%25%75% 
Peers Win Rate52%60%47%62%63%70% 
S&P 500 Win Rate75%42%67%75%67%50% 

Max Drawdowns [4]
GERN Max Drawdown-43%-31%-53%-35%-70%-44% 
Peers Max Drawdown-21%-18%-25%-23%-23%-17% 
S&P 500 Max Drawdown-5%-25%-10%-8%-19%-9% 


[1] Cumulative total returns since the beginning of 2021
[2] Peers: BMY, INCY, GILD, ABBV, AMGN.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 8/24/2026 (YTD)

How Low Can It Go

EventGERNS&P 500
Summer-Fall 2023 Five Percent Yield Shock
  % Loss-42.0%-9.5%
  % Gain to Breakeven72.4%10.5%
  Time to Breakeven126 days24 days
2023 SVB Regional Banking Crisis
  % Loss-27.0%-6.7%
  % Gain to Breakeven37.1%7.1%
  Time to Breakeven22 days31 days
2022 Inflation Shock & Fed Tightening
  % Loss-24.4%-24.5%
  % Gain to Breakeven32.3%32.4%
  Time to Breakeven55 days427 days
2020 COVID-19 Crash
  % Loss-31.7%-33.7%
  % Gain to Breakeven46.5%50.9%
  Time to Breakeven51 days140 days
Q4 2018 Fed Policy Error / Growth Scare
  % Loss-46.1%-19.2%
  % Gain to Breakeven85.4%23.8%
  Time to Breakeven90 days105 days
2016-2017 Trump Reflation Bond Selloff
  % Loss-20.3%-3.7%
  % Gain to Breakeven25.4%3.9%
  Time to Breakeven64 days6 days

Compare to BMY, INCY, GILD, ABBV, AMGN

In The Past

Geron's stock fell -6.7% during the 2024 Yen Carry Trade Unwind. Such a loss loss requires a 7.2% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

EventGERNS&P 500
Summer-Fall 2023 Five Percent Yield Shock
  % Loss-42.0%-9.5%
  % Gain to Breakeven72.4%10.5%
  Time to Breakeven126 days24 days
2023 SVB Regional Banking Crisis
  % Loss-27.0%-6.7%
  % Gain to Breakeven37.1%7.1%
  Time to Breakeven22 days31 days
2022 Inflation Shock & Fed Tightening
  % Loss-24.4%-24.5%
  % Gain to Breakeven32.3%32.4%
  Time to Breakeven55 days427 days
2020 COVID-19 Crash
  % Loss-31.7%-33.7%
  % Gain to Breakeven46.5%50.9%
  Time to Breakeven51 days140 days
Q4 2018 Fed Policy Error / Growth Scare
  % Loss-46.1%-19.2%
  % Gain to Breakeven85.4%23.8%
  Time to Breakeven90 days105 days
2016-2017 Trump Reflation Bond Selloff
  % Loss-20.3%-3.7%
  % Gain to Breakeven25.4%3.9%
  Time to Breakeven64 days6 days
2015-2016 China Devaluation / Global Growth Scare
  % Loss-30.5%-12.2%
  % Gain to Breakeven44.0%13.9%
  Time to Breakeven745 days62 days
2014-2016 Oil Price Collapse
  % Loss-22.3%-6.8%
  % Gain to Breakeven28.6%7.3%
  Time to Breakeven21 days15 days
2011 US Debt Ceiling Crisis & European Contagion
  % Loss-51.9%-17.9%
  % Gain to Breakeven108.0%21.8%
  Time to Breakeven744 days123 days
2010 Eurozone Sovereign Debt Crisis / Flash Crash
  % Loss-21.9%-15.4%
  % Gain to Breakeven28.0%18.2%
  Time to Breakeven27 days125 days
2008-2009 Global Financial Crisis
  % Loss-63.7%-53.4%
  % Gain to Breakeven175.8%114.4%
  Time to Breakeven106 days1085 days
Summer 2007 Credit Crunch
  % Loss-29.5%-8.6%
  % Gain to Breakeven41.9%9.5%
  Time to Breakeven62 days47 days

Compare to BMY, INCY, GILD, ABBV, AMGN

In The Past

Geron's stock fell -6.7% during the 2024 Yen Carry Trade Unwind. Such a loss loss requires a 7.2% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

About Geron (GERN)

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Geron Corporation (GERN) is a late-stage clinical biopharmaceutical company primarily focused on developing and commercializing new therapeutic treatments. Its core mission is to address myeloid hematologic malignancies, which are severe forms of blood cancer affecting the bone marrow and blood cells.

The company's lead product is imetelstat, a drug currently in Phase 3 clinical trials. Imetelstat operates as a telomerase inhibitor, a mechanism designed to block the uncontrolled proliferation of malignant stem and progenitor cells responsible for these cancers. By targeting telomerase, imetelstat aims to offer a novel approach to treating these challenging conditions.

Geron's primary market consists of patients suffering from specific blood disorders. Imetelstat is being developed to treat individuals diagnosed with low or intermediate-1 risk myelodysplastic syndromes (MDS) and those with intermediate-2 or high-risk myelofibrosis (MF). These are serious conditions, positioning Geron to serve patients and the medical community specializing in hematology and oncology.

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AI Analysis | Feedback

Analogy 1: A Moderna focused on developing breakthrough treatments for specific blood cancers, currently in late-stage clinical trials for its lead drug.

Analogy 2: Like a Vertex Pharmaceuticals dedicated to rare blood cancers, aiming to bring one key innovative therapy through its final clinical trials.

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  • imetelstat: A telomerase inhibitor in Phase 3 clinical trials for treating myeloid hematologic malignancies.

AI Analysis | Feedback

Geron Corporation is a late-stage clinical biopharmaceutical company with its lead product, imetelstat, currently in Phase 3 clinical trials. As such, it does not currently have commercial product customers generating sales revenue from a marketed drug. Upon successful clinical development and regulatory approval, Geron's major customers for imetelstat would primarily be companies and institutions within the healthcare supply chain responsible for the distribution and dispensing of prescription medications. These would include:
  • Pharmaceutical Wholesalers and Distributors: Large companies that purchase drugs directly from manufacturers and distribute them to pharmacies, hospitals, and other healthcare providers. Examples include AmerisourceBergen (NYSE: ABC), Cardinal Health (NYSE: CAH), and McKesson Corporation (NYSE: MCK).
  • Hospitals and Healthcare Systems: Medical institutions that purchase and administer prescription drugs for patient care, both in inpatient and outpatient settings.
  • Specialty Pharmacies: Pharmacies that specialize in the distribution and management of high-cost, high-touch, or complex medications, often for specific disease states or chronic conditions.

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Harout Semerjian, President and Chief Executive Officer, Board of Directors Member Harout Semerjian became President and Chief Executive Officer and a member of the Board of Directors of Geron Corporation starting August 7, 2025. Before joining Geron, he served as the Chief Executive Officer and President of GlycoMimetics, Inc., a position he held since August 6, 2021. Michelle Robertson, Executive Vice President, Chief Financial Officer and Treasurer Michelle Robertson holds the titles of Executive Vice President, Chief Financial Officer, and Treasurer at Geron Corporation. Joseph Eid, M.D., Executive Vice President, Research and Development, Chief Medical Officer Joseph Eid, M.D., serves as the Executive Vice President of Research and Development and Chief Medical Officer at Geron Corporation. Ahmed ElNawawi, Executive Vice President, Chief Commercial Officer Ahmed ElNawawi is the Executive Vice President and Chief Commercial Officer for Geron Corporation. Shannon T. Odam, Executive Vice President, Chief People Officer Shannon T. Odam is the Executive Vice President and Chief People Officer at Geron Corporation.

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The key risks to Geron's business are:

1. Regulatory Approval and Clinical Trial Outcomes for Imetelstat

Geron Corporation faces significant risk regarding the regulatory approval and commercialization success of its primary drug candidate, imetelstat. The FDA has raised substantial concerns about the benefit-risk profile of imetelstat, particularly highlighting the high incidence of severe adverse events (Grade 3-4 neutropenia and thrombocytopenia) in clinical trials compared to the observed efficacy in achieving transfusion independence in low-to-intermediate risk myelodysplastic syndromes (MDS) patients. The agency questioned whether the magnitude and durability of the treatment's effect outweigh its risks and noted that secondary endpoints, such as overall survival and complete remission, did not strongly support a disease-modifying effect. Furthermore, concerns were raised about the applicability of trial results to the U.S. population due to a small proportion of U.S. patients in the IMerge study. The postponement of pivotal IMpactMF trial results for myelofibrosis also adds to the uncertainty surrounding the drug's future prospects.

2. Product Concentration and Single Product Dependence

Geron's business model is heavily reliant on the success of imetelstat. The company's prospects are almost entirely tied to this single product. Should imetelstat encounter any further setbacks, such as non-approval, limited market adoption, or significant competition from existing or emerging treatments like Bristol Myers Squibb's Reblozyl, Geron lacks a diverse product portfolio to mitigate these impacts. This singular focus creates substantial vulnerability to market fluctuations, regulatory decisions, and unexpected clinical outcomes.

3. Financial Health and Funding

Geron has been identified as facing financial challenges, with a "Distressed" categorization and a history of net losses. Despite efforts to extend its funding runway through initiatives like a $150 million at-the-market equity offering, such actions introduce dilution risk for existing shareholders. The company anticipates continued operating expenses and may need to raise additional funds in the coming years to sustain operations, especially if imetelstat's commercial performance does not meet expectations. This ongoing need for capital underscores a significant financial risk.

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Geron Corporation's primary product, imetelstat (marketed as Rytelo), targets two main addressable markets: low or intermediate-1 risk myelodysplastic syndromes (MDS) and intermediate-2 or high-risk myelofibrosis (MF).

Myelodysplastic Syndromes (MDS)

The global market for myelodysplastic syndrome (MDS) drugs was valued at approximately USD 4.55 billion in 2024 and is projected to reach around USD 11.17 billion by 2034, exhibiting a compound annual growth rate (CAGR) of 9.4% from 2025 to 2034. Another estimate places the global MDS market at USD 3.454.5 million in 2023, with an expected growth to USD 15,325.39 million in 2032, at a CAGR of 5.56% between 2023 and 2032. In 2024, the U.S. myelodysplastic syndrome drugs market constituted approximately 30% of the global market. North America held a dominant share of the global MDS market, with a 36% revenue share in 2024 and is projected to lead with a 39.20% share in 2026. The U.S. market alone for MDS drugs reached approximately USD 1.2 billion in 2023.

Myelofibrosis (MF)

The global myelofibrosis (MF) treatment market was valued at over USD 834.5 million in 2025 and is estimated to reach USD 1,433.9 million by the end of 2035, growing at a CAGR of 6.2% from 2026 to 2035. Another report estimates the global myelofibrosis treatment market size at USD 1.2 billion in 2025, expected to reach USD 2.75 billion by 2032, at a CAGR of 12.3% from 2025 to 2032. The market across the seven major markets (7MM), which include the U.S., Germany, Italy, France, Spain, the UK, and Japan, was approximately USD 2.2 billion in 2024. This 7MM market is projected to grow from USD 2.6 billion in 2025 to USD 5.6 billion by 2034, reflecting a CAGR of 9%. The United States represents the largest myelofibrosis market, with a valuation of approximately USD 1,700 million in 2024. North America is anticipated to hold two-fifths of the global myelofibrosis treatment industry share in 2025.

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Expected Drivers of Future Revenue Growth for Geron (GERN) Over the Next 2-3 Years

Geron Corporation, trading under the symbol GERN, is poised for significant revenue growth over the next 2-3 years, primarily driven by the commercialization and expansion of its flagship product, RYTELO (imetelstat). RYTELO, a first-in-class telomerase inhibitor, has recently secured key regulatory approvals and is targeting substantial market opportunities in hematologic myeloid malignancies. The primary drivers of Geron's future revenue growth include:
  1. Increasing Commercial Sales of RYTELO in Lower-Risk Myelodysplastic Syndromes (LR-MDS) in the U.S. and Europe. RYTELO received FDA approval in June 2024 for adults with lower-risk MDS with transfusion-dependent anemia and subsequently gained European Union marketing authorization in March 2025. Geron has provided 2026 net revenue guidance for RYTELO ranging from $220 million to $240 million, with expectations of consistent quarter-over-quarter demand growth, especially in the latter half of the year. The company is strategically focused on expanding its commercial presence in the U.S. and refining its sales, marketing, and distribution efforts to maximize market penetration in this approved indication.
  2. Potential Expansion into the Myelofibrosis (MF) Indication. Imetelstat is currently in a pivotal Phase 3 IMpactMF clinical trial for relapsed/refractory myelofibrosis. An interim analysis for overall survival from this trial is anticipated in the second half of 2026. A positive outcome from the IMpactMF trial and subsequent regulatory approval would unlock a significant new market for RYTELO, considerably broadening its addressable patient population and providing a substantial driver of future revenue growth.
  3. Geographic Expansion of RYTELO Beyond Current U.S. and E.U. Markets. While RYTELO is approved in the U.S. and E.U. for LR-MDS, Geron is exploring potential global market opportunities and international expansion for the product. Successful navigation of regulatory pathways and commercial launches in additional countries would contribute to increased revenue streams over the next few years.
  4. Growth in Prescribing Accounts and Patient Demand. Geron's commercial strategy for 2026 targets the estimated 8,000 second-line lower-risk MDS patients in the U.S. through prioritized engagement of high-volume community accounts. The company has seen an increase in prescribing accounts and demand, and continued efforts to raise awareness among physicians and patients, along with expanding access and favorable insurance coverage, are expected to drive higher adoption rates and, consequently, revenue growth.

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Share Issuance

  • Geron launched a $150 million "at-the-market" (ATM) sales agreement for common stock with TD Securities (USA) LLC (TD Cowen) in February 2026, as part of a universal shelf registration.
  • In May 2025, stockholders approved amendments to equity incentive and employee stock purchase plans, increasing the share reserve by 20 million and 6 million shares, respectively, for employee stock-based compensation.
  • The company recently completed an upsized underwritten public offering of common stock and pre-funded warrants, generating total gross proceeds of $227.8 million, intended to fund preparatory activities for the potential U.S. commercial launch of imetelstat.

Inbound Investments

  • In January 2026, Geron amended its 5-year senior secured term loan facility with Pharmakon Advisors, LP, extending the deadline to July 30, 2026, for requesting Tranche B ($75 million) and Tranche C ($50 million) loans.
  • As of June 30, 2025, Geron maintained approximately $433 million in cash and marketable securities, with access to additional debt funding through its Pharmakon loan agreement.

Capital Expenditures

  • For 2026, Geron expects total operating expenses to be in the range of $230 million to $240 million, reflecting continued investment in RYTELO's commercial strategy and clinical development.
  • Total costs and operating expenses in 2025 were $254.7 million.
  • In December 2025, Geron initiated a strategic restructuring, including a workforce reduction, incurring $17.0 million in restructuring charges aimed at lowering future expenses.

Better Bets vs. Geron (GERN)

Peer Outperformance in Biotechnology

GERN has outperformed 76% of its 364 Biotechnology peers over 5Y. Biotechnology ranks 10th of 10 industries in Health Care by median 5Y return. The sector’s gains have largely come from elsewhere.
Share of Biotechnology constituents that GERN has outperformed, by holding period. Peers without a full price history over a given window are excluded from that window.
1Y
49%
of 460 industry peers · 4.1% return
3Y
45%
of 406 industry peers · -38.5% return
5Y
76%
of 364 industry peers · 11.8% return
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Median price return by industry across the Health Care sector, ranked by 5Y. Biotechnology is GERN's own industry. Use this to see which corners of the sector have carried the returns.
Industry Names 1Y med3Y med5Y med Top 3 by 5Y
Health Care Distributors 7 11.5%85.0%132.2% CAH 400% · MCK 348% · COR 189%
Health Care Services 20 20.9%46.0%3.9% HIMS 314% · RDNT 146% · DGX 80%
Managed Health Care 8 32.1%-1.6%3.5% OSCR 143% · HQY 64% · ELV 16%
Health Care Facilities 24 7.9%-2.8%-17.5% THC 278% · NHC 257% · ENSG 125%
Health Care Equipment 50 -2.9%-6.1%-21.0% POCI 10987% · UFPT 367% · GKOS 253%
Health Care Supplies 12 34.1%-12.7%-32.6% LNTH 301% · HAE 81% · MMSI 30%
Pharmaceuticals 63 4.3%6.4%-37.4% LQDA 2532% · INDV 1260% · ETON 1176%
Life Sciences Tools & Services 108 -3.6%-28.4%-72.7% SNWV 1827% · ELMD 249% · MEDP 243%
Health Care Technology 21 -21.8%-55.6%-74.4% SPOK 125% · HSTM -1% · VEEV -24%
Biotechnology ← 365 7.1%-26.0%-78.7% BRTX 106500% · CELZ 1629% · DNTH 1519%
Median of constituents with a full price history over each window. Top names are unfiltered by size in this render.

Recent Active Movers

Peer Comparisons

Peers to compare with:

Financials

GERNBMYINCYGILDABBVAMGNMedian
NameGeron Bristol-.Incyte Gilead S.AbbVie Amgen  
Mkt Price1.5267.28127.98146.74264.52443.84137.36
Mkt Cap1.0137.425.6182.4467.9239.7159.9
Rev LTM20549,1875,82030,45664,38638,09534,276
Op Inc LTM-3513,8421,84011,71621,85011,42611,571
FCF LTM-11511,4401,89012,94318,21010,17510,808
FCF 3Y Avg-16712,9888999,73618,0768,7549,245
CFO LTM-11412,7821,98013,55219,50712,47812,630
CFO 3Y Avg-16714,28297410,29619,14310,31210,304

Growth & Margins

GERNBMYINCYGILDABBVAMGNMedian
NameGeron Bristol-.Incyte Gilead S.AbbVie Amgen  
Rev Chg LTM24.4%3.1%26.9%5.5%10.4%9.1%9.7%
Rev Chg 3Y Avg4,035.6%2.9%18.5%3.6%4.9%12.8%8.8%
Rev Chg Q17.2%5.7%37.7%10.2%10.2%9.5%10.2%
QoQ Delta Rev Chg LTM4.3%1.5%8.6%2.4%2.5%2.4%2.5%
Op Inc Chg LTM54.4%39.1%85.0%7.6%59.5%39.5%47.0%
Op Inc Chg 3Y Avg29.9%22.3%552.7%-0.8%11.2%12.3%17.3%
Op Mgn LTM-17.2%28.1%31.6%38.5%33.9%30.0%30.8%
Op Mgn 3Y Avg-5,541.4%21.4%18.3%37.0%27.5%24.5%22.9%
QoQ Delta Op Mgn LTM0.6%0.1%4.6%-1.6%0.8%1.6%0.7%
CFO/Rev LTM-55.9%26.0%34.0%44.5%30.3%32.8%31.5%
CFO/Rev 3Y Avg-5,092.6%29.9%18.1%35.2%32.4%29.3%29.6%
FCF/Rev LTM-56.1%23.3%32.5%42.5%28.3%26.7%27.5%
FCF/Rev 3Y Avg-5,118.8%27.2%16.5%33.3%30.6%24.9%26.1%

Valuation

GERNBMYINCYGILDABBVAMGNMedian
NameGeron Bristol-.Incyte Gilead S.AbbVie Amgen  
Mkt Cap1.0137.425.6182.4467.9239.7159.9
P/S5.02.84.46.07.36.35.5
P/Op Inc-28.99.913.915.621.421.014.8
P/EBIT-27.310.113.0-190.640.318.511.5
P/E-15.114.815.9-56.374.227.415.4
P/CFO-8.910.713.013.524.019.213.2
Total Yield-6.6%10.5%6.3%0.5%3.9%5.9%4.9%
Dividend Yield0.0%3.7%0.0%2.2%2.6%2.2%2.2%
FCF Yield 3Y Avg-13.3%13.5%4.8%7.7%5.2%5.2%5.2%
D/E0.10.30.00.10.20.20.1
Net D/E-0.20.2-0.20.10.10.20.1

Returns

GERNBMYINCYGILDABBVAMGNMedian
NameGeron Bristol-.Incyte Gilead S.AbbVie Amgen  
1M Rtn7.0%8.4%8.8%13.5%2.0%18.7%8.6%
3M Rtn18.8%14.4%31.7%9.9%23.5%31.6%21.1%
6M Rtn-14.1%12.2%26.9%-0.9%17.1%18.6%14.6%
12M Rtn4.1%47.1%50.5%31.2%29.5%55.3%39.2%
3Y Rtn-38.5%24.8%100.4%110.7%100.0%89.4%94.7%
1M Excs Rtn3.8%5.1%5.5%10.2%-1.3%15.5%5.3%
3M Excs Rtn16.3%12.0%29.3%7.5%21.1%29.2%18.7%
6M Excs Rtn-26.0%0.3%15.0%-12.8%5.1%6.6%2.7%
12M Excs Rtn-13.8%25.5%27.8%9.5%10.0%35.3%17.7%
3Y Excs Rtn-115.5%-50.4%24.2%36.6%20.5%8.9%14.7%

Comparison Analyses

null

FDA Approved Drugs Data

Expand for More
Post-Approval Fwd Returns
FDA
App #
Brand
Name
Generic
Name
Dosage
Form
FDA
Approval
3M
Rtn
6M
Rtn
1Y
Rtn
2Y
Rtn
Total
Rtn
NDA217779  RYTELOimetelstat sodiumpowder606202410.0%2.3%-58.9%-69.9%-60.9%
Collapse to Preview
Post-Approval Fwd Returns
FDA
App #
Brand
Name
Generic
Name
Dosage
Form
FDA
Approval
3M
Rtn
6M
Rtn
1Y
Rtn
2Y
Rtn
Total
Rtn
NDA217779  RYTELOimetelstat sodiumpowder606202410.0%2.3%-58.9%-69.9%-60.9%

Financials

Segment Financials

Revenue by Segment
$ Mil20252024202320222021
Development of therapeutic products for oncology18477011
Total18477011


Operating Income by Segment
$ Mil20252024
Development of therapeutic products for oncology-69-174
Total-69-174


Net Income by Segment
$ Mil20252024
Development of therapeutic products for oncology-84-175
Total-84-175


Price Behavior

Price Behavior
Market Price$1.52 
Market Cap ($ Bil)1.0 
First Trading Date07/31/1996 
Distance from 52W High-22.1% 
   50 Days200 Days
DMA Price$1.42$1.42
DMA Trendupup
Distance from DMA7.4%6.8%
 3M1YR
Volatility69.1%64.2%
Downside Capture-176.91147.74
Upside Capture-76.26122.31
Correlation (SPY)-0.9%25.5%
GERN Betas & Captures as of 7/31/2026

 1M2M3M6M1Y3Y
Beta-0.500.080.331.351.361.10
Up Beta-1.560.49-0.060.571.010.91
Down Beta2.221.921.251.270.881.11
Up Capture-93%-57%-28%159%211%85%
Bmk +ve Days11223567138427
Stock +ve Days8172351107324
Down Capture-119%-92%58%158%140%109%
Bmk -ve Days11212859114326
Stock -ve Days10213160118374

[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with GERN
GERN6.3%64.1%0.34-
Sector ETF (XLV)29.3%16.0%1.4132.4%
Equity (SPY)21.2%12.9%1.2325.4%
Gold (GLD)39.0%28.8%1.1413.6%
Commodities (DBC)40.9%20.2%1.58-11.0%
Real Estate (VNQ)13.9%13.8%0.7013.8%
Bitcoin (BTCUSD)-30.4%44.2%-0.6912.4%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 5-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with GERN
GERN-7.6%70.9%0.19-
Sector ETF (XLV)6.9%15.1%0.2727.1%
Equity (SPY)12.8%17.2%0.5730.6%
Gold (GLD)20.6%18.6%0.906.5%
Commodities (DBC)10.2%19.6%0.411.9%
Real Estate (VNQ)2.4%18.9%0.0227.3%
Bitcoin (BTCUSD)11.2%52.8%0.4016.3%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 10-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with GERN
GERN-11.5%72.9%0.17-
Sector ETF (XLV)10.7%16.7%0.5223.4%
Equity (SPY)15.1%17.9%0.7225.6%
Gold (GLD)12.9%16.3%0.655.3%
Commodities (DBC)7.8%18.1%0.358.2%
Real Estate (VNQ)5.0%20.7%0.2018.6%
Bitcoin (BTCUSD)63.1%66.2%1.0310.1%

Smart multi-asset allocation framework can stack odds in your favor. Learn How

Short Interest

Short Interest: As Of Date7312026
Short Interest: Shares Quantity76.8 Mil
Short Interest: % Change Since 71520269.8%
Average Daily Volume7.8 Mil
Days-to-Cover Short Interest9.9 days
Basic Shares Quantity670.7 Mil
Short % of Basic Shares11.5%

Earnings Returns History

Updated 6/3/2026
Expand for More
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
2/25/2026-11.8%-26.2%-19.5%
11/5/2025-5.2%8.7%13.9%
8/6/202515.8%12.5%15.0%
5/7/2025-0.8%-9.1%18.2%
2/26/2025-32.1%-30.0%-28.3%
11/7/20240.5%-9.4%-8.0%
8/8/20240.9%-2.6%-6.8%
5/2/2024-3.2%-6.6%-13.0%
...
SUMMARY STATS   
# Positive121414
# Negative141212
Median Positive4.6%6.7%14.8%
Median Negative-5.4%-8.2%-14.9%
Max Positive20.3%14.6%43.6%
Max Negative-32.1%-30.0%-28.3%
Collapse to Preview
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
2/25/2026-11.8%-26.2%-19.5%
11/5/2025-5.2%8.7%13.9%
8/6/202515.8%12.5%15.0%
5/7/2025-0.8%-9.1%18.2%
2/26/2025-32.1%-30.0%-28.3%
11/7/20240.5%-9.4%-8.0%
8/8/20240.9%-2.6%-6.8%
5/2/2024-3.2%-6.6%-13.0%
1/8/20247.0%1.0%-6.0%
11/2/2023-7.8%-4.1%3.1%
8/3/2023-6.3%-4.7%-21.5%
5/11/20232.5%7.1%27.7%
3/16/2023-4.5%-14.0%-22.6%
1/4/2023-22.3%3.4%0.9%
11/3/2022-5.6%-3.3%7.0%
8/11/202214.6%6.8%35.6%
5/9/202220.3%14.6%14.6%
3/10/2022-0.9%6.4%43.6%
1/10/20220.9%2.6%-13.7%
11/10/2021-1.9%-9.0%-16.0%
8/16/20216.7%9.2%13.3%
5/10/202111.2%14.4%20.0%
3/11/2021-9.0%-7.4%-24.9%
1/8/20211.8%0.9%22.0%
11/5/2020-3.3%6.6%-2.7%
8/6/20201.2%0.6%10.2%
SUMMARY STATS   
# Positive121414
# Negative141212
Median Positive4.6%6.7%14.8%
Median Negative-5.4%-8.2%-14.9%
Max Positive20.3%14.6%43.6%
Max Negative-32.1%-30.0%-28.3%

SEC Filings

Expand for More
Report DateFiling DateFiling
06/30/202608/05/202610-Q
03/31/202605/06/202610-Q
12/31/202503/02/202610-K
09/30/202511/07/202510-Q
06/30/202508/06/202510-Q
03/31/202505/07/202510-Q
12/31/202402/27/202510-K
09/30/202411/07/202410-Q
06/30/202408/08/202410-Q
03/31/202405/02/202410-Q
12/31/202302/28/202410-K
09/30/202311/02/202310-Q
06/30/202308/03/202310-Q
03/31/202305/11/202310-Q
12/31/202203/16/202310-K
09/30/202211/07/202210-Q
Collapse to Preview
Report DateFiling DateFiling
06/30/202608/05/202610-Q
03/31/202605/06/202610-Q
12/31/202503/02/202610-K
09/30/202511/07/202510-Q
06/30/202508/06/202510-Q
03/31/202505/07/202510-Q
12/31/202402/27/202510-K
09/30/202411/07/202410-Q
06/30/202408/08/202410-Q
03/31/202405/02/202410-Q
12/31/202302/28/202410-K
09/30/202311/02/202310-Q
06/30/202308/03/202310-Q
03/31/202305/11/202310-Q
12/31/202203/16/202310-K
09/30/202211/07/202210-Q
06/30/202208/11/202210-Q
03/31/202205/09/202210-Q
12/31/202103/10/202210-K
09/30/202111/09/202110-Q
06/30/202108/16/202110-Q
03/31/202105/10/202110-Q
12/31/202003/11/202110-K
09/30/202011/05/202010-Q
06/30/202008/06/202010-Q
03/31/202005/28/202010-Q
12/31/201903/12/202010-K
09/30/201911/06/201910-Q

Recent Forward Guidance

Updated 7/27/2026

Latest: Q4 2025 Earnings Reported 2/25/2026

Forward GuidanceGuidance Change
MetricLowMidHigh% Chg% DeltaChangePrior
2026 RYTELO net product revenue220.00 Mil230.00 Mil240.00 Mil   
2026 Total operating expenses230.00 Mil235.00 Mil240.00 Mil-7.8% LoweredGuidance: 255.00 Mil for 2025

Prior: Q3 2025 Earnings Reported 11/5/2025

Forward GuidanceGuidance Change
MetricLowMidHigh% Chg% DeltaChangePrior
2025 Total Operating Expenses250.00 Mil255.00 Mil260.00 Mil-8.1% LoweredGuidance: 277.50 Mil for 2025

Insider Activity

Updated 7/1/2026
Expand for More
#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Robertson, MichelleEVP, CHIEF FINANCIAL OFFICERDirectSell21920261.949,85519,11934,231Form
Collapse to Preview
#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Robertson, MichelleEVP, CHIEF FINANCIAL OFFICERDirectSell21920261.949,85519,11934,231Form

Investor Activity (13F)

Updated Aug 25, 2026
13F holdings as of Mar 31, 2026 (Q1 2026)

Active managers (13F portfolio over $250M, at least 3 holdings) with a position over $5M that is either over 10% of their portfolio or held in a concentrated book of 50 or fewer total positions. Index/ETF, sovereign, bank, community-bank and charitable/donor-advised filers are excluded.

Active ManagerValue% of PortfolioTotal PositionsQoQFiling
Vivo Capital, LLC$12.9 Mil1.1%46TRIM -68.1%13F
Kynam Capital Management, LP$10.2 Mil0.6%36ADD +97.8%13F
Active ManagerValue% of PortfolioTotal PositionsQoQFiling
Kynam Capital Management, LP$10.2 Mil0.6%36ADD +97.8%13F
Active ManagerValue% of PortfolioTotal PositionsQoQFiling
Vivo Capital, LLC$12.9 Mil1.1%46TRIM -68.1%13F
Active ManagerValue% of PortfolioTotal PositionsQoQFiling
Vivo Capital, LLC$12.9 Mil1.1%46TRIM -68.1%13F
Kynam Capital Management, LP$10.2 Mil0.6%36ADD +97.8%13F
Core Cache Last Updated: 8/24/2026