Tearsheet

Medpace (MEDP)


Market Price (12/4/2025): $575.97 | Market Cap: $16.2 Bil
Sector: Health Care | Industry: Life Sciences Tools & Services

Medpace (MEDP)


Market Price (12/4/2025): $575.97
Market Cap: $16.2 Bil
Sector: Health Care
Industry: Life Sciences Tools & Services

Investment Highlights Why It Matters Which of these 2 stories sounds closer for this stock?

1. Generates cash flow

The stock generated 4% or more of the share price (called cash flow yield), and shows moderate 10-15% or more growth.

2. Riding a trend

Think Tesla during the pandemic of 2020 when EVs were riding a cultural high, or Nvidia in the current AI boom, or even Figma. These companies don’t have enough yield, or, enough growth, or both - however - they are riding a trend. They have momentum. These can be more volatile - they don’t have the floor of strong cash flow


0 Attractive operating margins
Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is 21%
Expensive valuation multiples
P/EBITPrice/EBIT or Price/(Operating Income) ratio is 29x, P/EPrice/Earnings or Price/(Net Income) is 33x
1 Attractive cash flow generation
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 30%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 29%
 
2 Megatrend and thematic drivers
Megatrends include Precision Medicine, and Biotechnology & Genomics. Themes include Biopharmaceutical R&D, Gene Editing & Therapy, Show more.
 
0 Attractive operating margins
Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is 21%
1 Attractive cash flow generation
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 30%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 29%
2 Megatrend and thematic drivers
Megatrends include Precision Medicine, and Biotechnology & Genomics. Themes include Biopharmaceutical R&D, Gene Editing & Therapy, Show more.
3 Expensive valuation multiples
P/EBITPrice/EBIT or Price/(Operating Income) ratio is 29x, P/EPrice/Earnings or Price/(Net Income) is 33x

Valuation, Metrics & Events

MEDP Stock


Why The Stock Moved


Qualitative Assessment

AI Generated Analysis | Feedback

I cannot fulfill this request as the specified time period (August 31, 2025, to December 4, 2025) is in the future.

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Stock Movement Drivers

Return vs. Risk


Price Returns Compared

 202020212022202320242025Total [1]
Returns
MEDP Return66%56%-2%44%8%76%594%
Peers Return42%10%-34%7%-4%15%22%
S&P 500 Return16%27%-19%24%23%16%112%

Monthly Win Rates [3]
MEDP Win Rate75%67%58%75%33%70% 
Peers Win Rate40%42%27%46%37%53% 
S&P 500 Win Rate58%75%42%67%75%70% 

Max Drawdowns [4]
MEDP Max Drawdown-27%-5%-40%-18%-7%-17% 
Peers Max Drawdown-29%-23%-47%-31%-29%-27% 
S&P 500 Max Drawdown-31%-1%-25%-1%-2%-15% 


[1] Cumulative total returns since the beginning of 2020
[2] Peers: PTGX, ANIK, CHRS, AVRT, BLLN.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2025 data is for the year up to 12/3/2025 (YTD)

How Low Can It Go

Unique KeyEventMEDPS&P 500
2022 Inflation Shock2022 Inflation Shock  
2022 Inflation Shock% Loss% Loss-42.9%-25.4%
2022 Inflation Shock% Gain to Breakeven% Gain to Breakeven75.0%34.1%
2022 Inflation ShockTime to BreakevenTime to Breakeven261 days464 days
2020 Covid Pandemic2020 Covid Pandemic  
2020 Covid Pandemic% Loss% Loss-39.5%-33.9%
2020 Covid Pandemic% Gain to Breakeven% Gain to Breakeven65.2%51.3%
2020 Covid PandemicTime to BreakevenTime to Breakeven119 days148 days
2018 Correction2018 Correction  
2018 Correction% Loss% Loss-39.0%-19.8%
2018 Correction% Gain to Breakeven% Gain to Breakeven64.1%24.7%
2018 CorrectionTime to BreakevenTime to Breakeven181 days120 days

Compare to PTGX, ANIK, CHRS, AVRT, BLLN


In The Past

Medpace's stock fell -42.9% during the 2022 Inflation Shock from a high on 12/27/2021. A -42.9% loss requires a 75.0% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth over time.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

About Medpace (MEDP)

Better Bets than Medpace (MEDP)

Latest Trefis Analyses

Trade Ideas

Select past ideas related to MEDP. For more, see Trefis Trade Ideas.

Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
CRL_11142025_Dip_Buyer_FCFYield11142025CRLCharles River Laboratories InternationalDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
4.1%4.1%-3.7%
GDRX_11142025_Dip_Buyer_High_CFO_Margins_ExInd_DE11142025GDRXGoodRxDip BuyDB | CFO/Rev | Low D/EDip Buy with High Cash Flow Margins
Buying dips for companies with significant cash flows from operations and reasonable debt / market cap
-9.8%-9.8%-11.8%
ASTH_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025ASTHAstrana HealthDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
6.0%6.0%-5.5%
SGRY_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025SGRYSurgery PartnersDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
9.7%9.7%-1.4%
TFX_11072025_Dip_Buyer_FCFYield11072025TFXTeleflexDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
6.2%6.2%-5.1%
MEDP_4302025_Dip_Buyer_ValueBuy04302025MEDPMedpaceDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
89.6%89.3%-6.4%
MEDP_8312022_Dip_Buyer_FCFYield08312022MEDPMedpaceDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
33.0%83.1%-1.7%
Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
CRL_11142025_Dip_Buyer_FCFYield11142025CRLCharles River Laboratories InternationalDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
4.1%4.1%-3.7%
GDRX_11142025_Dip_Buyer_High_CFO_Margins_ExInd_DE11142025GDRXGoodRxDip BuyDB | CFO/Rev | Low D/EDip Buy with High Cash Flow Margins
Buying dips for companies with significant cash flows from operations and reasonable debt / market cap
-9.8%-9.8%-11.8%
ASTH_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025ASTHAstrana HealthDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
6.0%6.0%-5.5%
SGRY_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025SGRYSurgery PartnersDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
9.7%9.7%-1.4%
TFX_11072025_Dip_Buyer_FCFYield11072025TFXTeleflexDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
6.2%6.2%-5.1%
MEDP_4302025_Dip_Buyer_ValueBuy04302025MEDPMedpaceDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
89.6%89.3%-6.4%
MEDP_8312022_Dip_Buyer_FCFYield08312022MEDPMedpaceDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
33.0%83.1%-1.7%

Recent Active Movers

Recent Active Movers

More From Trefis

Peer Comparisons for Medpace

Peers to compare with:

Financials

MEDPPTGXANIKCHRSAVRTBLLNMedian
NameMedpace Protagon.Anika Th.Coherus .Avertix .BillionT. 
Mkt Price576.4986.079.471.22-102.7686.07
Mkt Cap16.25.50.10.1--2.8
Rev LTM2,358209113278--243
Op Inc LTM50719-12-93--3
FCF LTM677641-90--32
FCF 3Y Avg53058-4-138--27
CFO LTM711658-90--37
CFO 3Y Avg566594-138--31

Growth & Margins

MEDPPTGXANIKCHRSAVRTBLLNMedian
NameMedpace Protagon.Anika Th.Coherus .Avertix .BillionT. 
Rev Chg LTM13.9%-35.4%30.6%152.1%--22.2%
Rev Chg 3Y Avg19.9%--6.2%30.9%--19.9%
Rev Chg Q23.7%0.8%-5.9%91.2%--12.3%
QoQ Delta Rev Chg LTM5.7%0.0%-1.5%2.0%--1.0%
Op Mgn LTM21.5%9.1%-11.0%-33.4%---1.0%
Op Mgn 3Y Avg19.8%-2.1%-108.0%--2.1%
QoQ Delta Op Mgn LTM0.1%-2.4%-2.9%1.6%---1.1%
CFO/Rev LTM30.2%31.3%7.2%-32.5%--18.7%
CFO/Rev 3Y Avg27.0%-3.9%-70.9%--3.9%
FCF/Rev LTM28.7%30.5%0.6%-32.5%--14.6%
FCF/Rev 3Y Avg25.3%--3.4%-71.0%---3.4%

Valuation

MEDPPTGXANIKCHRSAVRTBLLNMedian
NameMedpace Protagon.Anika Th.Coherus .Avertix .BillionT. 
Mkt Cap16.25.50.10.1--2.8
P/S6.120.21.20.7--3.7
P/EBIT28.5222.9-10.92.2--15.4
P/E33.492.3-4.11.2--17.3
P/CFO20.364.716.7-2.1--18.5
Total Yield3.0%1.1%-24.4%81.3%--2.0%
Dividend Yield0.0%0.0%0.0%0.0%--0.0%
FCF Yield 3Y Avg5.0%-0.8%-1.3%-56.9%---1.1%
D/E0.00.00.20.2--0.1
Net D/E-0.0-0.1-0.2-0.8---0.2

Returns

MEDPPTGXANIKCHRSAVRTBLLNMedian
NameMedpace Protagon.Anika Th.Coherus .Avertix .BillionT. 
1M Rtn-3.0%13.3%-3.6%-23.8%---3.3%
3M Rtn19.8%48.1%5.1%-3.2%--12.5%
6M Rtn84.3%67.0%-18.7%53.1%--60.1%
12M Rtn69.9%108.7%-45.4%-28.7%--20.6%
3Y Rtn175.8%966.5%-70.0%-82.4%--52.9%
1M Excs Rtn-2.9%13.4%-3.5%-23.7%---3.2%
3M Excs Rtn14.2%39.1%-1.2%-12.2%--6.5%
6M Excs Rtn69.6%52.3%-33.4%38.4%--45.3%
12M Excs Rtn55.7%83.0%-60.1%-13.5%--21.1%
3Y Excs Rtn98.3%996.6%-140.6%-153.9%---21.1%

Financials

Segment Financials

Revenue by Segment

$ Mil20242023202220212020
Single Segment1,886    
Antiviral and Anti-infective (AVAI) 11811110386
Cardiology 1751209591
Central Nervous System 1581228892
Metabolic 245160126139
Oncology 468363298257
Other 297267215196
Total1,8861,4601,142926861


Price Behavior

Short Interest

Short Interest: As Of Date11142025
Short Interest: Shares Quantity1,377,401
Short Interest: % Change Since 103120256.1%
Average Daily Volume246,315
Days-to-Cover Short Interest5.59
Basic Shares Quantity28,136,000
Short % of Basic Shares4.9%

SEC Filings

Expand for More

Report DateFiling DateFiling
93020251023202510-Q 9/30/2025
6302025722202510-Q 6/30/2025
3312025422202510-Q 3/31/2025
12312024211202510-K 12/31/2024
93020241022202410-Q 9/30/2024
6302024723202410-Q 6/30/2024
3312024423202410-Q 3/31/2024
12312023213202410-K 12/31/2023
93020231024202310-Q 9/30/2023
6302023725202310-Q 6/30/2023
3312023425202310-Q 3/31/2023
12312022214202310-K 12/31/2022
93020221025202210-Q 9/30/2022
6302022726202210-Q 6/30/2022
3312022426202210-Q 3/31/2022
12312021215202210-K 12/31/2021