Tearsheet

Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.

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Attractive cash flow generation
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 26%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 24%

Attractive yield
FCF Yield is 6.1%

Low stock price volatility
Vol 12M is 46%

Megatrend and thematic drivers
Megatrends include Precision Medicine, and Biotechnology & Genomics. Themes include Personalized Diagnostics, Targeted Therapies, Show more.

Trading close to highs
Dist 52W High is -2.3%

Weak multi-year price returns
2Y Excs Rtn is -24%, 3Y Excs Rtn is -84%

Key risks
LNTH key risks include [1] intensifying competition and pricing pressures eroding the market position of its flagship product, Show more.

0 Attractive cash flow generation
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 26%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 24%
1 Attractive yield
FCF Yield is 6.1%
2 Low stock price volatility
Vol 12M is 46%
3 Megatrend and thematic drivers
Megatrends include Precision Medicine, and Biotechnology & Genomics. Themes include Personalized Diagnostics, Targeted Therapies, Show more.
4 Trading close to highs
Dist 52W High is -2.3%
5 Weak multi-year price returns
2Y Excs Rtn is -24%, 3Y Excs Rtn is -84%
6 Key risks
LNTH key risks include [1] intensifying competition and pricing pressures eroding the market position of its flagship product, Show more.

Valuation, Metrics & Events

Price Chart

Why The Stock Moved

Qualitative Assessment

AI Analysis | Feedback

Lantheus (LNTH) stock has gained about 40% since 1/31/2026 because of the following key factors:

1. Strong Q1 2026 Financial Performance: Lantheus reported robust first-quarter 2026 results on May 7, 2026, with adjusted diluted earnings per share (EPS) of $1.46, exceeding analysts' consensus estimates by 18.7% to 18.8%. The company's revenue reached $377.3 million, surpassing expectations. Worldwide revenue increased 1.2% year-over-year, and 8.6% when excluding divested SPECT revenues. Additionally, Lantheus reaffirmed its full-year 2026 financial guidance, projecting revenue between $1.4 billion and $1.45 billion and adjusted EPS of $5.00 to $5.25, signaling continued positive outlook.

2. Key Regulatory Approvals for Enhanced Product Portfolio: Lantheus secured significant regulatory approvals within the period. On March 6, 2026, the FDA approved PYLARIFY TruVu (piflufolastat F18), a new formulation of its market-leading PSMA PET imaging agent, designed to boost manufacturing efficiency and supply, with a phased launch anticipated in the fourth quarter of 2026. Furthermore, on March 2, 2026, the company received tentative FDA approval for Lutetium Lu 177 Dotatate (PNT2003), positioning it as a potential first radioequivalent for gastroenteropancreatic neuroendocrine tumors.

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Stock Movement Drivers

Fundamental Drivers

The 41.2% change in LNTH stock from 1/31/2026 to 5/21/2026 was primarily driven by a 64.2% change in the company's Net Income Margin (%).
(LTM values as of)13120265212026Change
Stock Price ($)66.9294.4741.2%
Change Contribution By: 
Total Revenues ($ Mil)1,5261,5461.3%
Net Income Margin (%)11.0%18.0%64.2%
P/E Multiple26.821.9-18.3%
Shares Outstanding (Mil)67653.9%
Cumulative Contribution41.2%

LTM = Last Twelve Months as of date shown

Market Drivers

1/31/2026 to 5/21/2026
ReturnCorrelation
LNTH41.2% 
Market (SPY)7.6%39.6%
Sector (XLV)-3.9%26.6%

Fundamental Drivers

The 63.8% change in LNTH stock from 10/31/2025 to 5/21/2026 was primarily driven by a 50.3% change in the company's P/E Multiple.
(LTM values as of)103120255212026Change
Stock Price ($)57.6994.4763.8%
Change Contribution By: 
Total Revenues ($ Mil)1,5211,5461.7%
Net Income Margin (%)17.8%18.0%1.3%
P/E Multiple14.621.950.3%
Shares Outstanding (Mil)69655.8%
Cumulative Contribution63.8%

LTM = Last Twelve Months as of date shown

Market Drivers

10/31/2025 to 5/21/2026
ReturnCorrelation
LNTH63.8% 
Market (SPY)9.5%29.7%
Sector (XLV)3.6%33.2%

Fundamental Drivers

The -9.5% change in LNTH stock from 4/30/2025 to 5/21/2026 was primarily driven by a -11.4% change in the company's Net Income Margin (%).
(LTM values as of)43020255212026Change
Stock Price ($)104.3494.47-9.5%
Change Contribution By: 
Total Revenues ($ Mil)1,5341,5460.8%
Net Income Margin (%)20.4%18.0%-11.4%
P/E Multiple23.121.9-5.2%
Shares Outstanding (Mil)69656.9%
Cumulative Contribution-9.5%

LTM = Last Twelve Months as of date shown

Market Drivers

4/30/2025 to 5/21/2026
ReturnCorrelation
LNTH-9.5% 
Market (SPY)35.5%10.8%
Sector (XLV)7.3%20.5%

Fundamental Drivers

The 10.6% change in LNTH stock from 4/30/2023 to 5/21/2026 was primarily driven by a 501.2% change in the company's Net Income Margin (%).
(LTM values as of)43020235212026Change
Stock Price ($)85.4594.4710.6%
Change Contribution By: 
Total Revenues ($ Mil)9351,54665.4%
Net Income Margin (%)3.0%18.0%501.2%
P/E Multiple208.621.9-89.5%
Shares Outstanding (Mil)69655.8%
Cumulative Contribution10.6%

LTM = Last Twelve Months as of date shown

Market Drivers

4/30/2023 to 5/21/2026
ReturnCorrelation
LNTH10.6% 
Market (SPY)85.6%13.8%
Sector (XLV)16.6%19.5%

Return vs. Risk

Price Returns Compared

 202120222023202420252026Total [1]
Returns
LNTH Return114%76%22%44%-26%44%612%
Peers Return2%-51%7%-37%-17%2%-72%
S&P 500 Return27%-19%24%23%16%9%98%

Monthly Win Rates [3]
LNTH Win Rate75%58%67%67%67%100% 
Peers Win Rate43%35%47%48%42%40% 
S&P 500 Win Rate75%42%67%75%67%60% 

Max Drawdowns [4]
LNTH Max Drawdown-21%-44%-44%-38%-54%-12% 
Peers Max Drawdown-48%-61%-44%-52%-58%-36% 
S&P 500 Max Drawdown-5%-25%-10%-8%-19%-9% 


[1] Cumulative total returns since the beginning of 2021
[2] Peers: CRSP, DNLI, NEOG, NTLA, QDEL.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 5/21/2026 (YTD)

How Low Can It Go

EventLNTHS&P 500
2024 Yen Carry Trade Unwind
  % Loss-10.6%-7.8%
  % Gain to Breakeven11.9%8.5%
  Time to Breakeven9 days18 days
Summer-Fall 2023 Five Percent Yield Shock
  % Loss-28.2%-9.5%
  % Gain to Breakeven39.4%10.5%
  Time to Breakeven293 days24 days
2022 Inflation Shock & Fed Tightening
  % Loss-16.7%-24.5%
  % Gain to Breakeven20.1%32.4%
  Time to Breakeven20 days427 days
2020 COVID-19 Crash
  % Loss-44.9%-33.7%
  % Gain to Breakeven81.4%50.9%
  Time to Breakeven314 days140 days
Q4 2018 Fed Policy Error / Growth Scare
  % Loss-17.9%-19.2%
  % Gain to Breakeven21.8%23.8%
  Time to Breakeven9 days105 days
2015-2016 China Devaluation / Global Growth Scare
  % Loss-78.6%-12.2%
  % Gain to Breakeven367.8%13.9%
  Time to Breakeven203 days62 days

Compare to CRSP, DNLI, NEOG, NTLA, QDEL

In The Past

Lantheus's stock fell -9.3% during the 2025 US Tariff Shock. Such a loss loss requires a 10.2% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

EventLNTHS&P 500
Summer-Fall 2023 Five Percent Yield Shock
  % Loss-28.2%-9.5%
  % Gain to Breakeven39.4%10.5%
  Time to Breakeven293 days24 days
2020 COVID-19 Crash
  % Loss-44.9%-33.7%
  % Gain to Breakeven81.4%50.9%
  Time to Breakeven314 days140 days
2015-2016 China Devaluation / Global Growth Scare
  % Loss-78.6%-12.2%
  % Gain to Breakeven367.8%13.9%
  Time to Breakeven203 days62 days
2014-2016 Oil Price Collapse
  % Loss-73.0%-6.8%
  % Gain to Breakeven269.9%7.3%
  Time to Breakeven189 days15 days

Compare to CRSP, DNLI, NEOG, NTLA, QDEL

In The Past

Lantheus's stock fell -9.3% during the 2025 US Tariff Shock. Such a loss loss requires a 10.2% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

About Lantheus (LNTH)

Lantheus Holdings, Inc. develops, manufactures, and commercializes diagnostic and therapeutic products that assist clinicians in the diagnosis and treatment of heart, cancer, and other diseases worldwide. It provides DEFINITY, a microbubble ultrasound enhancing agent used in ultrasound exams of the heart; TechneLite, a technetium generator for nuclear medicine; Xenon-133 to assess pulmonary function; Neurolite to identify the area within the brain where blood flow has been blocked or reduced due to stroke; Cardiolite, an injectable Tc-99m-labeled imaging agent; Thallium-201 to detect cardiovascular disease; and Gallium-67 to detect various infections and cancerous tumors. The company also offers AZEDRA, a radiotherapeutic to treat adult and pediatric patients; Automated Bone Scan Index that calculates the disease burden of prostate cancer by quantifying the hotspots on bone scans; and Cobalt (Co 57), a non-pharmaceutical radiochemical; RELISTOR for opioid-induced constipation; and PYLARIFY for visualization of lymph nodes, bone, and soft tissue metastases to determine the presence or absence of recurrent and/or metastatic prostate cancer. It also develops flurpiridaz F 18 to assess blood flow to the heart; 1095, a PSMA-targeted iodine-131 labeled small molecule; LMI 1195 for neuroblastoma tumors in pediatric and adults; PYLARIFY AI, an AI-based medical device software to perform standardized quantitative assessment of PSMA PET/CT images in prostate cancer; and leronlimab, an investigational humanized monoclonal antibody. The company serves radio pharmacies, distributors, integrated delivery networks, hospitals, clinics, and group practices. It has strategic partnerships with NanoMab Technology Limited; Bausch Health Companies, Inc.; GE Healthcare Limited; Curium; Bayer AG; CytoDyn Inc.; ROTOP; FUJIFILM; Regeneron Pharmaceuticals, Inc.; and POINT Biopharma US Inc. The company was founded in 1956 and is headquartered in North Billerica, Massachusetts.

AI Analysis | Feedback

Here are 1-2 brief analogies for Lantheus:

  • Think of them as a highly specialized pharmaceutical company, similar to a niche Eli Lilly or Novartis, but focused on advanced diagnostic imaging agents and targeted radiotherapies for heart disease and cancer.
  • Imagine a focused GE Healthcare or Siemens Healthineers that provides the 'special dyes' and radioactive tracers for advanced medical scans and treatments, rather than the large imaging machines themselves.

AI Analysis | Feedback

  • DEFINITY: A microbubble ultrasound enhancing agent used in ultrasound exams of the heart.
  • TechneLite: A technetium generator for nuclear medicine.
  • Xenon-133: Used to assess pulmonary function.
  • Neurolite: An agent to identify areas of blocked or reduced blood flow in the brain due to stroke.
  • Cardiolite: An injectable imaging agent used for cardiac imaging.
  • Thallium-201: Used to detect cardiovascular disease.
  • Gallium-67: Used to detect various infections and cancerous tumors.
  • AZEDRA: A radiotherapeutic to treat adult and pediatric patients.
  • Automated Bone Scan Index (ABSI): Software that calculates the disease burden of prostate cancer by quantifying hotspots on bone scans.
  • Cobalt (Co 57): A non-pharmaceutical radiochemical.
  • RELISTOR: A product for treating opioid-induced constipation.
  • PYLARIFY: An agent for visualizing metastases in prostate cancer, including lymph nodes, bone, and soft tissue.

AI Analysis | Feedback

Lantheus (LNTH) primarily sells its diagnostic and therapeutic products to other organizations rather than directly to individuals. Based on the provided description, its major customers fall into the following categories:

  • Radio pharmacies
  • Distributors
  • Integrated delivery networks
  • Hospitals
  • Clinics
  • Group practices

As these are broad categories of customers and not specific named public companies, company symbols are not applicable in this context.

AI Analysis | Feedback

Major Suppliers:

  • Bausch Health Companies, Inc. (BHC)
  • GE Healthcare Limited (GEHC)
  • Curium
  • Bayer AG (BAYRY)
  • CytoDyn Inc. (CYDY)
  • ROTOP
  • FUJIFILM (FUJIY)
  • Regeneron Pharmaceuticals, Inc. (REGN)
  • NanoMab Technology Limited
  • POINT Biopharma US Inc.

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Mary Anne Heino Executive Chairperson and Interim CEO
Mary Anne Heino serves as interim Chief Executive Officer and Executive Chairperson of Lantheus. She previously held the position of CEO from August 2015 to March 2024. Ms. Heino joined Lantheus in April 2013 as Chief Commercial Officer and was promoted to Chief Operating Officer in March 2015. With nearly 20 years of executive leadership, her background includes senior commercial and strategic leadership roles at Angelini Labopharm, Labopharm USA, and Centocor (a Johnson & Johnson company), preceded by a career in sales management at Janssen Pharmaceutica. She led Angelini Labopharm LLC and Labopharm USA as president and SVP of worldwide sales and marketing from February 2007 to March 2012. Under her leadership, Lantheus acquired Progenics in June 2020.

Robert J. Marshall Jr. Chief Financial Officer
Robert J. Marshall Jr. joined Lantheus as Chief Financial Officer and Treasurer in September 2018. He brings over 30 years of finance experience, including expertise in M&A, capital markets, and investor relations. Prior to Lantheus, Mr. Marshall spent 16 years with Zimmer Biomet Holdings, Inc., a global medical device company, where he held various senior leadership roles such as Vice President, Investor Relations, Corporate Treasurer, and Vice President.

Cheryl Ball Chief Strategy Officer and Head of Corporate Development
Cheryl Ball joined Lantheus in 2019 and serves as Chief Strategy Officer and Head of Corporate Development. Her responsibilities include leading corporate development efforts, establishing portfolio management functions, and overseeing annual strategic planning processes. Prior to Lantheus, she held leadership roles at Acorn Strategies as Vice President of Portfolio Planning and at Evidera as Senior Director of Corporate Strategy and Portfolio Management. Her earlier experience includes director roles at AstraZeneca and Quintiles, focusing on strategic assessments and market strategy initiatives.

Ludger Dinkelborg, PhD Head of Research and Development
Ludger Dinkelborg, PhD, was appointed Head of Research and Development at Lantheus, effective August 1, 2025, following the company's acquisition of Life Molecular Imaging Ltd. He previously served as CEO and Managing Director of Life Molecular Imaging and is a co-founder of the company. Dr. Dinkelborg oversees global research and development activities in oncological, neurodegenerative, and cardiovascular indications. He also held positions as Director at Piramal Imaging SA.

Amanda Morgan Chief Commercial Officer
Amanda Morgan was promoted to Chief Commercial Officer at Lantheus, effective March 25, 2024, having joined the company in November 2022 as Senior Vice President, Commercial. She possesses over 20 years of experience in the healthcare industry. Before joining Lantheus, Ms. Morgan was the Chief Revenue and Customer Officer at Acadia Pharmaceuticals, where she led the commercial organization. She also held various leadership roles with increasing responsibility at Shire Plc, including U.S. Head of Sales and U.S. Head of Patient Services, and held leadership roles at Baxter.

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Key Business Risks for Lantheus Holdings, Inc.

Lantheus Holdings, Inc. faces several key risks inherent in the biotechnology and pharmaceutical industries.

1. Clinical Development and Regulatory Approval Risk for Pipeline Products: Lantheus has a significant pipeline of investigational products, including flurpiridaz F 18, 1095, LMI 1195, PYLARIFY AI, and leronlimab, an investigational humanized monoclonal antibody. The success of these products is highly dependent on favorable outcomes in clinical trials and obtaining regulatory approvals from health authorities. Failure to demonstrate efficacy and safety, delays in clinical development, or inability to secure regulatory clearance for these pipeline candidates could significantly impact the company's future growth prospects and financial performance.

2. Competition and Market Acceptance of Existing Products: The markets for Lantheus's diagnostic and therapeutic products, such as DEFINITY, TechneLite, PYLARIFY, and others, are highly competitive. The continued commercial success of these products is subject to intense competition from existing and new market entrants, pricing pressures, evolving clinical practice guidelines, and the potential for alternative therapies or technologies to emerge. A decline in market acceptance or increased competition for its key commercialized products could adversely affect the company's revenues and profitability.

3. Specialized Supply Chain and Manufacturing Risks for Radiopharmaceuticals: A substantial portion of Lantheus's product portfolio consists of radiopharmaceuticals (e.g., TechneLite, Xenon-133, Cardiolite, Thallium-201, Gallium-67, AZEDRA). These products rely on the secure and timely supply of medical isotopes and other specialized raw materials, which often have complex and geographically concentrated global supply chains. Any disruptions in the production of these isotopes, manufacturing processes, or distribution networks due to regulatory issues, operational failures, or unforeseen events could severely impact Lantheus's ability to produce and sell its radiopharmaceutical products.

AI Analysis | Feedback

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AI Analysis | Feedback

Lantheus (symbol: LNTH) operates in several significant addressable markets with its key diagnostic and therapeutic products:

  • PYLARIFY (prostate cancer imaging): The U.S. market potential for PSMA PET imaging, in which PYLARIFY is the number one utilized agent, may exceed $3.5 billion by the end of the decade. The global prostate cancer diagnostics market size was estimated at USD 9.72 billion in 2025 and is predicted to increase to approximately USD 18 billion by 2035, growing at a CAGR of 6.36% from 2026 to 2035. North America held the largest market share, 46%, in the global prostate cancer diagnostics market in 2025. The U.S. prostate cancer nuclear medicine diagnostics market size reached USD 119.06 million in 2023 and is projected to reach approximately USD 289.71 million by 2033, expanding at a CAGR of 9.2%.
  • DEFINITY (microbubble ultrasound enhancing agent): The global microbubbles/ultrasound contrast agents market was valued at USD 2.62 billion in 2024 and is poised to grow to USD 3.93 billion by 2033, with a CAGR of 4.6% during the forecast period (2026–2033). The overall global ultrasound-enhancing agents market was valued at US$ 756.61 million in 2023 and is projected to reach US$ 2,511.52 million by 2031, with an estimated CAGR of 16.2%. North America holds the largest market share in the ultrasound contrast agents market, accounting for approximately 35% of the global market. The global high-density ultrasound contrast agent market size was valued at USD 157 million in 2024 and is projected to grow to USD 471 million by 2032, exhibiting a CAGR of 17.2%.
  • TechneLite (technetium generator): The Technetium-99m market size is projected to reach US$ 4.54 billion in 2024 and US$ 6.03 billion by 2031, registering a CAGR of 4.2% during 2025–2031. The global Technetium 99m market size was valued at USD 6,482.4 million in 2025 and is expected to reach USD 10,122.5 million by 2034, growing at a CAGR of 5.02%. Another estimate places the global Technetium-99m (Tc-99m) market at USD 5.6 billion in 2024, projected to reach USD 8.1 billion by 2030, reflecting a CAGR of 6.3%. North America maintained a 37.67% share of the technetium-99m market size in 2024.
  • AZEDRA (radiotherapeutic for pheochromocytoma and paraganglioma):AZEDRA was discontinued in 2023 due to insufficient commercial demand, with manufacturing continuing only until Q1 2024. The pheochromocytomas and paragangliomas market size in the 7MM (7 Major Markets: US, EU4, UK, and Japan) is expected to grow from USD 314 million in 2025 to USD 662 million in 2034. The global paraganglioma market size was valued at USD 304.18 million in 2024 and is projected to grow from USD 316.71 million in 2025 to USD 437.46 million by 2033, with a CAGR of 4.12%. North America is the most significant global paraganglioma market shareholder.
  • flurpiridaz F 18 (to assess blood flow to the heart): The Flurpiridaz market is projected to grow from USD 546.9 million in 2025 to USD 1202.6 million by 2035, at a CAGR of 8.2%. From 2020 to 2024, the flurpiridaz market expanded from USD 353.8 million to USD 508.6 million. The market is expected to record a rapid expansion trajectory with a compound annual growth rate (CAGR) of 12.1%. GE HealthCare holds a dominant global position (83.5% in 2024) in the flurpiridaz market.
  • NEURACEQ (Alzheimer's radiodiagnostic): Lantheus estimates the Alzheimer's radiodiagnostic market could be a $1.5 billion total addressable market by the end of the decade and $2.5 billion by the mid-2030s. Neuraceq exited 2025 as the second largest and fastest growing commercially approved amyloid PET imaging agent utilized in the U.S.

AI Analysis | Feedback

Lantheus Holdings, Inc. (LNTH) is expected to drive future revenue growth over the next 2-3 years through a combination of new product launches, significant expansion in the Alzheimer's diagnostic market, and the continued performance of its core products.

Here are 3-5 expected drivers of future revenue growth:

  1. Launch and Expansion of New PET Radiodiagnostics: Lantheus anticipates multiple FDA approvals and commercial launches of new products within its radiodiagnostics pipeline. Key among these are OCTEVY, a PET radiodiagnostic for GEP-NET imaging with a PDUFA date of March 29, 2026, and a new formulation of PYLARIFY, aimed at increasing batch size and efficiency, with a PDUFA date of March 6, 2026. These launches are expected to provide meaningful revenue contributions starting in 2027. Additionally, royalties from flurpiridaz F 18, an FDA-approved PET myocardial perfusion imaging agent for coronary artery disease that became available in early 2025, will contribute to revenue.
  2. Growth in the Alzheimer's Disease PET Imaging Market with Neuraceq: The acquisition of Neuraceq, an approved radiodiagnostic for Alzheimer's disease, positions Lantheus for significant growth in the expanding Alzheimer's disease PET imaging market. The company projects triple-digit inorganic growth for Neuraceq in 2026, driven by the increasing adoption of disease-modifying therapies for Alzheimer's and expanded diagnostic guidelines.
  3. Continued Performance and New Formulation of PYLARIFY: Despite facing intensified competition and some pricing pressure, PYLARIFY remains a leading PSMA PET imaging agent for prostate cancer and a major revenue contributor. While net revenue for PYLARIFY is expected to decline 8-10% in 2026 due to these dynamics, increased volume is still anticipated. The planned transition to a new, more efficient PYLARIFY formulation from late 2026 onwards is expected to enhance patient access, supply resilience, and production efficiency, supporting future growth and market leadership.
  4. Steady Growth of DEFINITY: DEFINITY, Lantheus's microbubble ultrasound enhancing agent for heart exams, is a stable product in the company's portfolio. It is projected to continue generating revenue growth in the low to mid-single digits over the next few years.

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Share Repurchases

  • Lantheus' board of directors authorized a program in November 2024 to repurchase up to $250 million of its common stock over the next twelve months.
  • In August 2025, this program was superseded by a new authorization to repurchase up to $400 million of common stock through December 31, 2027.
  • The company repurchased $100 million of common stock in the third quarter of 2025 and another $100 million in the fourth quarter of 2025.

Share Issuance

  • Lantheus' shares outstanding increased from 70,905 shares (in thousands) as of December 31, 2024, to 71,607 shares (in thousands) as of March 31, 2025.

Outbound Investments

  • In 2025, Lantheus completed the acquisition of Evergreen Theragnostics, Inc., costing $276.4 million, which added OCTEVY and radioligand therapy manufacturing infrastructure.
  • In 2025, the company also completed the acquisition of Life Molecular Imaging, for approximately $355.2 million to $352.9 million, bringing Neuraceq and an expanded commercial footprint.
  • Lantheus divested its legacy SPECT business, effective January 1, 2026, to SHINE Technologies LLC, to strategically focus on innovative PET radiodiagnostics.

Capital Expenditures

  • Capital expenditures totaled $27.301 million for the full year 2025, a decrease from $35.256 million in 2024.
  • In the fourth quarter of 2025, capital expenditures were $8.8 million, which was $7.6 million less than the prior year's fourth quarter.
  • For 2026, Lantheus plans to invest in commercialization infrastructure, sales and marketing for new products like the new PSMA PET formulation and OCTEVY, and R&D for phase-gated projects, prioritizing radiodiagnostics.

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Peer Comparisons

Peers to compare with:

Financials

LNTHCRSPDNLINEOGNTLAQDELMedian
NameLantheus CRISPR T.Denali T.Neogen Intellia.QuidelOr. 
Mkt Price94.4749.9019.308.8612.3712.3915.85
Mkt Cap6.14.83.61.91.50.82.8
Rev LTM1,54610871662,657468
Op Inc LTM290-646-547-38-421-21-229
FCF LTM372-426-4216-364-159-262
FCF 3Y Avg356-301-410-17-388-105-203
CFO LTM408-400-41269-3637-178
CFO 3Y Avg419-289-39779-38282-105

Growth & Margins

LNTHCRSPDNLINEOGNTLAQDELMedian
NameLantheus CRISPR T.Denali T.Neogen Intellia.QuidelOr. 
Rev Chg LTM0.6%-97.1%--3.9%45.0%-3.9%-3.9%
Rev Chg 3Y Avg15.4%-5.0%-7.5%10.0%-5.1%7.5%
Rev Chg Q1.2%---4.4%-9.5%-10.5%-7.0%
QoQ Delta Rev Chg LTM0.3%---1.1%-2.3%-2.7%-1.7%
Op Inc Chg LTM-36.2%-36.3%-6.2%-254.6%22.2%-124.8%-36.2%
Op Inc Chg 3Y Avg512.9%-16.1%-35.5%-68.0%-1.3%-77.9%-25.8%
Op Mgn LTM18.8%-64,639.5%--4.4%-636.6%-0.8%-4.4%
Op Mgn 3Y Avg27.7%-22,035.2%-1.9%-935.8%2.3%1.9%
QoQ Delta Op Mgn LTM-1.7%---1.0%15.1%-2.8%-1.4%
CFO/Rev LTM26.4%-39,996.4%-8.0%-549.5%0.2%0.2%
CFO/Rev 3Y Avg28.1%-13,643.7%-8.7%-715.9%2.9%2.9%
FCF/Rev LTM24.0%-42,617.6%-0.7%-550.2%-6.0%-6.0%
FCF/Rev 3Y Avg23.9%-14,519.9%--1.9%-727.1%-3.8%-3.8%

Valuation

LNTHCRSPDNLINEOGNTLAQDELMedian
NameLantheus CRISPR T.Denali T.Neogen Intellia.QuidelOr. 
Mkt Cap6.14.83.61.91.50.82.8
P/S4.04,793.0-2.222.20.34.0
P/Op Inc21.1-7.4-6.6-50.7-3.5-39.7-7.0
P/EBIT15.5-7.4-6.6-3.4-3.5-0.9-3.5
P/E21.9-8.4-7.1-3.2-3.7-0.7-3.4
P/CFO15.0-12.0-8.727.8-4.0128.05.5
Total Yield4.6%-11.9%-14.1%-31.6%-26.9%-143.3%-20.5%
Dividend Yield0.0%0.0%0.0%0.0%0.0%0.0%0.0%
FCF Yield 3Y Avg6.8%-7.6%-14.0%-0.8%-30.5%-6.5%-7.1%
D/E0.10.20.00.40.13.40.1
Net D/E0.0-0.3-0.30.3-0.23.2-0.1

Returns

LNTHCRSPDNLINEOGNTLAQDELMedian
NameLantheus CRISPR T.Denali T.Neogen Intellia.QuidelOr. 
1M Rtn15.8%-10.2%-4.1%-5.9%-19.2%2.9%-5.0%
3M Rtn29.1%-8.7%-4.6%-19.3%-5.1%-47.5%-6.9%
6M Rtn76.3%1.2%12.5%63.8%53.9%-41.9%33.2%
12M Rtn25.7%34.9%41.0%42.4%34.5%-58.1%34.7%
3Y Rtn-3.9%-24.2%-38.7%-45.5%-72.1%-86.1%-42.1%
1M Excs Rtn9.7%-15.9%-9.0%-11.2%-29.7%-0.2%-10.1%
3M Excs Rtn20.1%-14.4%-12.2%-29.6%-9.9%-52.6%-13.3%
6M Excs Rtn64.1%-19.2%-2.1%37.1%33.5%-54.3%15.7%
12M Excs Rtn-2.4%1.8%9.7%17.6%2.6%-87.1%2.2%
3Y Excs Rtn-84.2%-100.3%-115.3%-128.1%-152.9%-166.8%-121.7%

Comparison Analyses

null

FDA Approved Drugs Data

Expand for More
Post-Approval Fwd Returns
FDA
App #
Brand
Name
Generic
Name
Dosage
Form
FDA
Approval
3M
Rtn
6M
Rtn
1Y
Rtn
2Y
Rtn
Total
Rtn
NDA204677  NEURACEQflorbetaben f-18solution3192014     
NDA021711  ABLAVARgadofosveset trisodiumsolution12222008     

Financials

Segment Financials

Revenue by Segment
$ Mil20252024202320222021
PYLARIFY1,05885152743 
DEFINITY318280245233196
TechneLite9587899185
Strategic partnerships and other revenue3852472512
Other precision diagnostics2423232737
Other radiopharmaceutical oncology034510
Neuraceq0    
Total1,5341,296935425339


Price Behavior

Price Behavior
Market Price$94.47 
Market Cap ($ Bil)6.2 
First Trading Date06/25/2015 
Distance from 52W High-2.3% 
   50 Days200 Days
DMA Price$83.50$66.52
DMA Trendupup
Distance from DMA13.1%42.0%
 3M1YR
Volatility38.6%46.4%
Downside Capture92.2950.65
Upside Capture157.0962.44
Correlation (SPY)44.6%14.3%
LNTH Betas & Captures as of 4/30/2026

 1M2M3M6M1Y3Y
Beta1.171.180.980.800.410.51
Up Beta0.880.630.420.490.480.53
Down Beta3.550.750.78-0.190.160.39
Up Capture133%178%183%199%14%17%
Bmk +ve Days15223166141428
Stock +ve Days12193364127388
Down Capture288%133%81%83%72%81%
Bmk -ve Days4183056108321
Stock -ve Days10243161124364

[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with LNTH
LNTH23.7%46.5%0.62-
Sector ETF (XLV)12.0%14.7%0.5527.6%
Equity (SPY)26.8%12.1%1.6714.1%
Gold (GLD)37.5%26.8%1.163.4%
Commodities (DBC)43.5%18.6%1.80-8.4%
Real Estate (VNQ)12.0%13.4%0.5920.7%
Bitcoin (BTCUSD)-27.2%41.8%-0.655.1%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 5-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with LNTH
LNTH35.1%57.3%0.75-
Sector ETF (XLV)5.4%14.6%0.1926.0%
Equity (SPY)13.8%17.0%0.6426.8%
Gold (GLD)19.3%18.0%0.876.5%
Commodities (DBC)10.8%19.4%0.4410.2%
Real Estate (VNQ)3.8%18.8%0.1027.5%
Bitcoin (BTCUSD)9.3%55.6%0.377.1%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 10-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with LNTH
LNTH45.5%62.0%0.86-
Sector ETF (XLV)9.8%16.5%0.4829.7%
Equity (SPY)15.5%17.9%0.7431.9%
Gold (GLD)13.2%16.0%0.683.0%
Commodities (DBC)7.8%17.9%0.3513.9%
Real Estate (VNQ)5.4%20.7%0.2229.2%
Bitcoin (BTCUSD)67.3%66.9%1.066.4%

Smart multi-asset allocation framework can stack odds in your favor. Learn How

Short Interest

Short Interest: As Of Date4302026
Short Interest: Shares Quantity5.7 Mil
Short Interest: % Change Since 415202611.1%
Average Daily Volume0.7 Mil
Days-to-Cover Short Interest8.4 days
Basic Shares Quantity64.7 Mil
Short % of Basic Shares8.8%

Earnings Returns History

Expand for More
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
5/7/20265.6%12.0% 
2/26/2026-0.4%2.8%0.8%
11/6/2025-6.2%-4.8%8.8%
8/6/2025-28.6%-25.8%-25.9%
5/7/2025-23.2%-24.7%-23.4%
1/28/2025-7.3%-8.9%-5.1%
11/6/2024-20.7%-25.9%-22.3%
7/31/2024-4.5%-10.6%-0.1%
...
SUMMARY STATS   
# Positive81112
# Negative14119
Median Positive14.8%12.0%8.1%
Median Negative-6.5%-15.9%-16.4%
Max Positive39.1%81.6%76.5%
Max Negative-28.6%-25.9%-25.9%

SEC Filings

Expand for More
Report DateFiling DateFiling
03/31/202605/07/202610-Q
12/31/202502/26/202610-K
09/30/202511/06/202510-Q
06/30/202508/06/202510-Q
03/31/202505/07/202510-Q
12/31/202402/26/202510-K
09/30/202411/06/202410-Q
06/30/202407/31/202410-Q
03/31/202405/02/202410-Q
12/31/202302/22/202410-K
09/30/202311/02/202310-Q
06/30/202308/03/202310-Q
03/31/202305/04/202310-Q
12/31/202202/23/202310-K
09/30/202211/03/202210-Q
06/30/202208/04/202210-Q

Recent Forward Guidance [BETA]

Latest: Q1 2026 Earnings Reported 5/7/2026

Forward GuidanceGuidance Change
MetricLowMidHigh% Chg% DeltaChangePrior
2026 Revenue1.40 Bil1.43 Bil1.45 Bil0 AffirmedGuidance: 1.43 Bil for 2026
2026 Adjusted fully diluted EPS55.125.250 AffirmedGuidance: 5.12 for 2026

Prior: Q4 2025 Earnings Reported 2/26/2026

Forward GuidanceGuidance Change
MetricLowMidHigh% Chg% DeltaChangePrior
2026 Revenue1.40 Bil1.43 Bil1.45 Bil-5.0% Lower NewActual: 1.50 Bil for 2025
2026 Adjusted fully diluted EPS55.125.25-8.1% Lower NewActual: 5.58 for 2025

Insider Activity

Expand for More
#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Patel, Rajiv A See FootnotesSell821202556.153,365,000188,944,750195,246,296Form
2Farallon, Partners L L C/ca See FootnotesSell821202556.153,365,000188,944,750195,246,296Form
3Patel, Rajiv A See FootnotesSell821202555.3441,0002,268,940378,648,842Form
4Farallon, Partners L L C/ca See FootnotesSell821202555.3441,0002,268,940378,648,842Form
5Blanchfield, PaulPresidentDirectSell815202553.573,060163,9245,797,024Form