AbbVie (ABBV)
Market Price (12/23/2025): $227.5 | Market Cap: $402.4 BilSector: Health Care | Industry: Biotechnology
AbbVie (ABBV)
Market Price (12/23/2025): $227.5Market Cap: $402.4 BilSector: Health CareIndustry: Biotechnology
Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.
| Attractive operating marginsOp Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is 24% | Weak multi-year price returns3Y Excs Rtn is -21% | Expensive valuation multiplesP/EBITPrice/EBIT or Price/(Operating Income) ratio is 89x, P/EPrice/Earnings or Price/(Net Income) is 169x |
| Attractive cash flow generationCFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 35%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 33%, CFO LTM is 21 Bil, FCF LTM is 20 Bil | Key risksABBV key risks include [1] the steep decline of Humira sales due to biosimilar competition, Show more. | |
| Attractive yieldDividend Yield is 2.9% | ||
| Low stock price volatilityVol 12M is 26% | ||
| Megatrend and thematic driversMegatrends include Biotechnology & Genomics, Precision Medicine, and Aging Population & Chronic Disease. Themes include Advanced Diagnostics, Show more. |
| Attractive operating marginsOp Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is 24% |
| Attractive cash flow generationCFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 35%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 33%, CFO LTM is 21 Bil, FCF LTM is 20 Bil |
| Attractive yieldDividend Yield is 2.9% |
| Low stock price volatilityVol 12M is 26% |
| Megatrend and thematic driversMegatrends include Biotechnology & Genomics, Precision Medicine, and Aging Population & Chronic Disease. Themes include Advanced Diagnostics, Show more. |
| Weak multi-year price returns3Y Excs Rtn is -21% |
| Expensive valuation multiplesP/EBITPrice/EBIT or Price/(Operating Income) ratio is 89x, P/EPrice/Earnings or Price/(Net Income) is 169x |
| Key risksABBV key risks include [1] the steep decline of Humira sales due to biosimilar competition, Show more. |
Why The Stock Moved
Qualitative Assessment
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Here are the key points highlighting factors that contributed to AbbVie's stock movement: 1. Strong Q4 2024 Financial Performance and Optimistic 2025 OutlookAbbVie reported better-than-expected fourth-quarter 2024 earnings and revenue, and subsequently raised its full-year 2025 adjusted earnings per share guidance. This strong financial performance and positive outlook for the coming year likely boosted investor confidence. 2. Expanded Indications for Key Immunology Drug Rinvoq
Rinvoq (upadacitinib) received U.S. FDA approval in April 2025 for the treatment of Giant Cell Arteritis (GCA), following European Commission approval in April 2025. These expanded indications for Rinvoq broaden its market reach and contribute to AbbVie's immunology portfolio growth. Show more
Stock Movement Drivers
Fundamental Drivers
The 3.1% change in ABBV stock from 9/22/2025 to 12/22/2025 was primarily driven by a 62.6% change in the company's P/E Multiple.| 9222025 | 12222025 | Change | |
|---|---|---|---|
| Stock Price ($) | 221.00 | 227.91 | 3.13% |
| Change Contribution By | LTM | LTM | |
| Total Revenues ($ Mil) | 58328.00 | 59644.00 | 2.26% |
| Net Income Margin (%) | 6.45% | 4.00% | -37.94% |
| P/E Multiple | 103.83 | 168.83 | 62.60% |
| Shares Outstanding (Mil) | 1768.00 | 1769.00 | -0.06% |
| Cumulative Contribution | 3.13% |
Market Drivers
9/22/2025 to 12/22/2025| Return | Correlation | |
|---|---|---|
| ABBV | 3.1% | |
| Market (SPY) | 2.7% | 3.1% |
| Sector (XLV) | 13.7% | 65.0% |
Fundamental Drivers
The 26.0% change in ABBV stock from 6/23/2025 to 12/22/2025 was primarily driven by a 121.5% change in the company's P/E Multiple.| 6232025 | 12222025 | Change | |
|---|---|---|---|
| Stock Price ($) | 180.88 | 227.91 | 26.00% |
| Change Contribution By | LTM | LTM | |
| Total Revenues ($ Mil) | 57367.00 | 59644.00 | 3.97% |
| Net Income Margin (%) | 7.31% | 4.00% | -45.25% |
| P/E Multiple | 76.23 | 168.83 | 121.47% |
| Shares Outstanding (Mil) | 1768.00 | 1769.00 | -0.06% |
| Cumulative Contribution | 26.00% |
Market Drivers
6/23/2025 to 12/22/2025| Return | Correlation | |
|---|---|---|
| ABBV | 26.0% | |
| Market (SPY) | 14.4% | 3.2% |
| Sector (XLV) | 18.0% | 60.8% |
Fundamental Drivers
The 34.3% change in ABBV stock from 12/22/2024 to 12/22/2025 was primarily driven by a 188.2% change in the company's P/E Multiple.| 12222024 | 12222025 | Change | |
|---|---|---|---|
| Stock Price ($) | 169.65 | 227.91 | 34.34% |
| Change Contribution By | LTM | LTM | |
| Total Revenues ($ Mil) | 55533.00 | 59644.00 | 7.40% |
| Net Income Margin (%) | 9.22% | 4.00% | -56.59% |
| P/E Multiple | 58.59 | 168.83 | 188.15% |
| Shares Outstanding (Mil) | 1769.00 | 1769.00 | 0.00% |
| Cumulative Contribution | 34.34% |
Market Drivers
12/22/2024 to 12/22/2025| Return | Correlation | |
|---|---|---|
| ABBV | 34.3% | |
| Market (SPY) | 16.9% | 30.3% |
| Sector (XLV) | 14.5% | 67.9% |
Fundamental Drivers
The 56.0% change in ABBV stock from 12/23/2022 to 12/22/2025 was primarily driven by a 774.6% change in the company's P/E Multiple.| 12232022 | 12222025 | Change | |
|---|---|---|---|
| Stock Price ($) | 146.13 | 227.91 | 55.97% |
| Change Contribution By | LTM | LTM | |
| Total Revenues ($ Mil) | 57819.00 | 59644.00 | 3.16% |
| Net Income Margin (%) | 23.19% | 4.00% | -82.73% |
| P/E Multiple | 19.30 | 168.83 | 774.65% |
| Shares Outstanding (Mil) | 1771.00 | 1769.00 | 0.11% |
| Cumulative Contribution | 55.96% |
Market Drivers
12/23/2023 to 12/22/2025| Return | Correlation | |
|---|---|---|
| ABBV | 57.8% | |
| Market (SPY) | 47.7% | 22.8% |
| Sector (XLV) | 18.4% | 59.9% |
Price Returns Compared
| 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total [1] | |
|---|---|---|---|---|---|---|---|
| Returns | |||||||
| ABBV Return | 28% | 32% | 24% | -0% | 19% | 32% | 229% |
| Peers Return | 7% | 30% | 20% | -3% | 7% | 19% | 105% |
| S&P 500 Return | 16% | 27% | -19% | 24% | 23% | 17% | 113% |
Monthly Win Rates [3] | |||||||
| ABBV Win Rate | 58% | 75% | 67% | 50% | 67% | 58% | |
| Peers Win Rate | 47% | 55% | 63% | 38% | 47% | 55% | |
| S&P 500 Win Rate | 58% | 75% | 42% | 67% | 75% | 73% | |
Max Drawdowns [4] | |||||||
| ABBV Max Drawdown | -26% | -3% | -2% | -16% | 0% | -4% | |
| Peers Max Drawdown | -22% | -7% | -11% | -23% | -10% | -17% | |
| S&P 500 Max Drawdown | -31% | -1% | -25% | -1% | -2% | -15% | |
[1] Cumulative total returns since the beginning of 2020
[2] Peers: JNJ, PFE, MRK, BMY, LLY. See ABBV Returns vs. Peers.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2025 data is for the year up to 12/22/2025 (YTD)
How Low Can It Go
| Event | ABBV | S&P 500 |
|---|---|---|
| 2022 Inflation Shock | ||
| % Loss | -23.3% | -25.4% |
| % Gain to Breakeven | 30.4% | 34.1% |
| Time to Breakeven | 495 days | 464 days |
| 2020 Covid Pandemic | ||
| % Loss | -34.0% | -33.9% |
| % Gain to Breakeven | 51.6% | 51.3% |
| Time to Breakeven | 99 days | 148 days |
| 2018 Correction | ||
| % Loss | -48.9% | -19.8% |
| % Gain to Breakeven | 95.6% | 24.7% |
| Time to Breakeven | 847 days | 120 days |
Compare to LLY, MRK, AMGN, GILD, BMY
In The Past
AbbVie's stock fell -23.3% during the 2022 Inflation Shock from a high on 4/8/2022. A -23.3% loss requires a 30.4% gain to breakeven.
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AbbVie Inc. discovers, develops, manufactures, and sells pharmaceuticals in the worldwide. The company offers HUMIRA, a therapy administered as an injection for autoimmune and intestinal Behçet's diseases; SKYRIZI to treat moderate to severe plaque psoriasis in adults; RINVOQ, a JAK inhibitor for the treatment of moderate to severe active rheumatoid arthritis in adult patients; IMBRUVICA to treat adult patients with chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), and VENCLEXTA, a BCL-2 inhibitor used to treat adults with CLL or SLL; and MAVYRET to treat patients with chronic HCV genotype 1-6 infection. It also provides CREON, a pancreatic enzyme therapy for exocrine pancreatic insufficiency; Synthroid used in the treatment of hypothyroidism; Linzess/Constella to treat irritable bowel syndrome with constipation and chronic idiopathic constipation; Lupron for the palliative treatment of advanced prostate cancer, endometriosis and central precocious puberty, and patients with anemia caused by uterine fibroids; and Botox therapeutic. In addition, the company offers ORILISSA, a nonpeptide small molecule gonadotropin-releasing hormone antagonist for women with moderate to severe endometriosis pain; Duopa and Duodopa, a levodopa-carbidopa intestinal gel to treat Parkinson's disease; Lumigan/Ganfort, a bimatoprost ophthalmic solution for the reduction of elevated intraocular pressure (IOP) in patients with open angle glaucoma (OAG) or ocular hypertension; Ubrelvy to treat migraine with or without aura in adults; Alphagan/ Combigan, an alpha-adrenergic receptor agonist for the reduction of IOP in patients with OAG; and Restasis, a calcineurin inhibitor immunosuppressant to increase tear production, as well as other eye care products. AbbVie Inc. has a research collaboration with Dragonfly Therapeutics, Inc. The company was incorporated in 2012 and is headquartered in North Chicago, Illinois.
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Here are 1-3 brief analogies for AbbVie:
- A major pharmaceutical company like Pfizer, specializing in immunology, oncology, and neuroscience.
- Amgen, but with a broader portfolio of blockbuster drugs spanning immunology, oncology, and aesthetics.
- The dedicated research and drug development arm of a company like Abbott Laboratories, but operating as an independent entity.
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- Humira (adalimumab): A blockbuster biologic drug for various autoimmune and inflammatory conditions such as rheumatoid arthritis, psoriasis, and Crohn's disease.
- Skyrizi (risankizumab): An interleukin-23 inhibitor used to treat moderate to severe plaque psoriasis, psoriatic arthritis, and Crohn's disease.
- Rinvoq (upadacitinib): A JAK inhibitor approved for several inflammatory conditions, including rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, and atopic dermatitis.
- Botox (onabotulinumtoxinA): A neurotoxin widely used for both cosmetic purposes (reducing wrinkles) and therapeutic indications such as chronic migraine and muscle spasticity.
- Venclexta/Venclyxto (venetoclax): An oral medication for certain types of leukemia and lymphoma, specifically chronic lymphocytic leukemia (CLL) and acute myeloid leukemia (AML).
- Imbruvica (ibrutinib): A Bruton's tyrosine kinase (BTK) inhibitor used to treat various B-cell cancers, including chronic lymphocytic leukemia and mantle cell lymphoma.
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AbbVie (ABBV) primarily sells its pharmaceutical products to other companies, specifically major pharmaceutical wholesale distributors.
Its major customers in the United States, based on recent financial disclosures, are the three largest pharmaceutical wholesale distributors. These companies purchase a significant portion of AbbVie's products for distribution to pharmacies, hospitals, and other healthcare providers:
- AmerisourceBergen Corporation (Symbol: ABC)
- Cardinal Health, Inc. (Symbol: CAH)
- McKesson Corporation (Symbol: MCK)
These three distributors collectively account for a substantial majority of AbbVie's gross revenues in the United States.
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The public company AbbVie (ABBV) faces several key risks to its business, primarily stemming from patent expirations and the need to successfully launch and grow new products.
- Loss of Exclusivity for Humira and Biosimilar Competition: AbbVie's former top-selling drug, Humira (adalimumab), has faced the "patent cliff," with numerous biosimilar versions entering the market since 2023. This has already led to a significant decline in Humira's sales, with U.S. sales dropping by one-third in 2023 and expected to decline further in 2024. The company has spent years trying to lessen its reliance on Humira, which once accounted for more than half of its revenue.
- Pipeline Strength and Over-reliance on Skyrizi and Rinvoq: To offset the revenue loss from Humira, AbbVie is heavily relying on its immunology drugs Skyrizi (risankizumab) and Rinvoq (upadacitinib) to fill the gap. While these drugs have shown promising growth and the company anticipates them generating significant combined sales, there are concerns among analysts that AbbVie's late-stage pipeline is "lighter" compared to its peers. Recent pipeline setbacks, such as the discontinuation of an experimental Alzheimer's drug and the failure of emraclidine in Phase 2 trials, highlight the inherent risks in drug development and the importance of a robust pipeline for sustained growth.
- Competition and Regulatory/Pricing Pressures: Beyond biosimilar competition for Humira, AbbVie faces increasing competition in other therapeutic areas, such as oncology, where its drug Imbruvica has seen sales declines due to competitive dynamics. The broader pharmaceutical industry also faces policy risks, including potential changes to laws and regulations, and pricing pressures from initiatives like the Inflation Reduction Act, which can impact the profitability of high-priced drugs.
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- The emergence of next-generation neurotoxins, such as Daxxify (daxibotulinumtoxinA) by Revance Therapeutics, approved in 2022, offers a longer duration of effect compared to traditional botulinum toxins like AbbVie's Botox. This directly challenges Botox's market dominance by providing a differentiated product that may reduce the frequency of treatments, representing a clear new competitive pressure.
- Increased competition in the immunology market from recently approved and highly efficacious biologics and small molecules. Examples include Eli Lilly's Omvoh (mirikizumab) for ulcerative colitis, which received approvals in late 2023 and early 2024 in key markets, and Bristol Myers Squibb's Sotyktu (deucravacitinib) for psoriasis. These new entrants directly compete with AbbVie's key immunology assets like Skyrizi and Rinvoq, intensifying the fight for market share.
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AbbVie (ABBV) operates in several significant addressable markets for its main products and services, primarily focusing on immunology, oncology, and aesthetics.
- Humira (adalimumab): The global market size for Humira was estimated at approximately USD 10.34 billion in 2024. This market is projected to decline to about USD 4.11 billion by 2030, primarily due to the increasing availability of biosimilars following patent expirations. North America holds a leading position in the Humira market, accounting for 85.7% of the global share in 2024, with the U.S. dominating within North America.
- Skyrizi (risankizumab): Global sales for Skyrizi are projected to reach USD 17.1 billion in 2025. In 2024, its sales were approximately USD 11.7 billion. Combined with Rinvoq, AbbVie anticipates their immunology portfolio will generate over USD 31 billion in sales by 2027. North America was the largest region for Skyrizi in 2024.
- Rinvoq (upadacitinib): Global sales for Rinvoq are projected to be USD 8 billion in 2025. Its sales in 2024 were around USD 6 billion. The combined sales of Rinvoq and Skyrizi are expected to exceed USD 31 billion by 2027. The market size for Giant Cell Arteritis (GCA), one of its indications, is estimated to grow from USD 960 million in the 7 major markets (7MM) in 2023.
- Imbruvica (ibrutinib): The global Imbruvica market size was approximately USD 9.6982 billion in 2024. It is expected to expand to USD 44.462 billion by 2031, with a compound annual growth rate (CAGR) of 24.30% from 2024 to 2031. North America accounted for over 40% of the global revenue for Imbruvica in 2024.
- Botox (Botulinum Toxin): The global botulinum toxin market, which includes Botox, was valued at USD 9.77 billion in 2025 and is forecast to reach USD 15.10 billion by 2030. The medical Botox market specifically had a size of USD 5.4122 million in 2024 and is projected to reach USD 10.2158 billion by 2031, growing at a CAGR of 9.50% from 2024 to 2031. North America held the highest market share in the botulinum toxin market in 2024.
- Venclexta/Venclyxto (venetoclax): The global venetoclax market size was valued at USD 1.22 billion in 2024 and is estimated to reach USD 2.43 billion by 2033, growing at a CAGR of 12.92% from 2025 to 2033. North America dominates this global market.
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AbbVie (ABBV) is anticipated to drive future revenue growth over the next two to three years through several key strategies:
- Continued Growth of Immunology Blockbusters: The strong performance of immunology drugs SKYRIZI and RINVOQ is a significant growth driver. These products are consistently exceeding sales expectations, with projections for combined sales to surpass $15 billion by 2027 and over $31 billion by 2027 due to expanded indications and global market penetration.
- Expansion and Performance of the Neuroscience Portfolio: AbbVie's neuroscience portfolio, featuring products such as Vraylar, Botox Therapeutic, Ubrelvy, and Qulipta, is demonstrating robust double-digit revenue growth. Strategic acquisitions, including Cerevel Therapeutics, are expected to further bolster this segment and address unmet needs in neurodegenerative diseases.
- Advancements in the Oncology Pipeline: The oncology portfolio, with products like Venclexta, is also contributing to growth. The acquisition of ImmunoGen is poised to catalyze further expansion and innovation within AbbVie's oncology offerings.
- Strategic Investments in R&D and External Innovation: AbbVie is actively investing in research and development and pursuing strategic acquisitions to strengthen its pipeline across core therapeutic areas like immunology, oncology, neuroscience, and new growth areas such as obesity and mood disorders. Recent deals, including the acquisition of Gilgamesh Pharmaceuticals and Capstan Therapeutics, aim to expand the psychiatry and immunology pipelines, respectively.
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Capital Allocation Decisions (Last 3-5 Years) for AbbVie (ABBV)
Share Repurchases
- AbbVie repurchased 10 million shares for $1.6 billion in 2023, 8 million shares for $1.1 billion in 2022, and 7 million shares for $1.3 billion in 2024.
- On February 16, 2023, AbbVie's board of directors authorized a $5.0 billion increase to the existing stock repurchase authorization.
- The remaining stock repurchase authorization was $3.5 billion as of December 31, 2024.
Share Issuance
- AbbVie's shares outstanding were 1.773 billion in 2024, showing a 0% decline from 2023.
- Shares outstanding were 1.773 billion in 2023, a 0.28% decline from 2022.
- The company issued and redeemed $7.7 billion of commercial paper during 2024.
Outbound Investments
- AbbVie acquired ImmunoGen for $10.1 billion in February 2024 (agreement in November 2023) to accelerate its entry into the ovarian cancer treatment market.
- The company acquired Cerevel Therapeutics for $8.7 billion in August 2024 (agreement in December 2023) to significantly strengthen its neuroscience pipeline.
- AbbVie's deal activity surged in 2024 with 17 deals, primarily licensing and R&D collaborations to enhance its pipeline, including a partnership with FutureGen Biopharmaceutical for up to $1.7 billion for Inflammatory Bowel Disease treatment.
Capital Expenditures
- AbbVie's capital expenditures averaged $806.2 million annually from 2020 to 2024, with $974 million in 2024 and a peak of $1.044 billion in the latest twelve months (as of June 2025).
- The company plans to invest over $10 billion in U.S. manufacturing during the next decade to support volume growth and expand into new therapeutic areas like obesity.
- A $195 million investment in its North Chicago manufacturing plant to expand domestic active pharmaceutical ingredient (API) production is set to begin construction in fall 2025 and be fully operational by 2027.
Latest Trefis Analyses
| Title | |
|---|---|
| ARTICLES |
Trade Ideas
Select ideas related to ABBV. For more, see Trefis Trade Ideas.
| Date | Ticker | Company | Category | Trade Strategy | 6M Fwd Rtn | 12M Fwd Rtn | 12M Max DD |
|---|---|---|---|---|---|---|---|
| 11142025 | CRL | Charles River Laboratories International | Dip Buy | DB | FCFY OPMDip Buy with High FCF Yield and High MarginBuying dips for companies with high FCF yield and meaningfully high operating margin | 17.4% | 17.4% | -3.7% |
| 11142025 | GDRX | GoodRx | Dip Buy | DB | CFO/Rev | Low D/EDip Buy with High Cash Flow MarginsBuying dips for companies with significant cash flows from operations and reasonable debt / market cap | -6.7% | -6.7% | -11.8% |
| 11142025 | ASTH | Astrana Health | Dip Buy | DB | FCF Yield | Low D/EDip Buy with High Free Cash Flow YieldBuying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap | 10.9% | 10.9% | -5.5% |
| 11142025 | SGRY | Surgery Partners | Dip Buy | DB | FCF Yield | Low D/EDip Buy with High Free Cash Flow YieldBuying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap | 2.7% | 2.7% | -1.4% |
| 11072025 | TFX | Teleflex | Dip Buy | DB | FCFY OPMDip Buy with High FCF Yield and High MarginBuying dips for companies with high FCF yield and meaningfully high operating margin | 11.4% | 11.4% | -5.1% |
| 04302022 | ABBV | AbbVie | Quality | Q | Momentum | UpsideQuality Stocks with Momentum and UpsideBuying quality stocks with strong momentum but still having room to run | 2.5% | 6.9% | -7.8% |
| 10312018 | ABBV | AbbVie | Dip Buy | DB | FCFY OPMDip Buy with High FCF Yield and High MarginBuying dips for companies with high FCF yield and meaningfully high operating margin | 3.9% | 8.0% | -15.8% |
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Peer Comparisons for AbbVie
| Peers to compare with: |
Financials
| Median | |
|---|---|
| Name | |
| Mkt Price | 156.02 |
| Mkt Cap | 332.2 |
| Rev LTM | 61,215 |
| Op Inc LTM | 18,904 |
| FCF LTM | 14,176 |
| FCF 3Y Avg | 13,642 |
| CFO LTM | 16,843 |
| CFO 3Y Avg | 16,176 |
Growth & Margins
| Median | |
|---|---|
| Name | |
| Rev Chg LTM | 4.5% |
| Rev Chg 3Y Avg | 2.0% |
| Rev Chg Q | 5.2% |
| QoQ Delta Rev Chg LTM | 1.3% |
| Op Mgn LTM | 25.4% |
| Op Mgn 3Y Avg | 25.1% |
| QoQ Delta Op Mgn LTM | 1.7% |
| CFO/Rev LTM | 26.4% |
| CFO/Rev 3Y Avg | 27.3% |
| FCF/Rev LTM | 20.3% |
| FCF/Rev 3Y Avg | 21.1% |
Valuation
| Median | |
|---|---|
| Name | |
| Mkt Cap | 332.2 |
| P/S | 4.7 |
| P/EBIT | 13.8 |
| P/E | 19.2 |
| P/CFO | 17.3 |
| Total Yield | 8.7% |
| Dividend Yield | 3.0% |
| FCF Yield 3Y Avg | 5.5% |
| D/E | 0.2 |
| Net D/E | 0.1 |
Returns
| Median | |
|---|---|
| Name | |
| 1M Rtn | 1.6% |
| 3M Rtn | 21.5% |
| 6M Rtn | 29.5% |
| 12M Rtn | 22.6% |
| 3Y Rtn | 15.3% |
| 1M Excs Rtn | -1.9% |
| 3M Excs Rtn | 17.4% |
| 6M Excs Rtn | 15.9% |
| 12M Excs Rtn | 6.3% |
| 3Y Excs Rtn | -60.2% |
Comparison Analyses
FDA Approved Drugs Data
Expand for More| Post-Approval Fwd Returns | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| FDA App # | Brand Name | Generic Name | Dosage Form | FDA Approval | 3M Rtn | 6M Rtn | 1Y Rtn | 2Y Rtn | Total Rtn |
| NDA217906 | EMBLAVEO | avibactam sodium | powder | 2072025 | -2.3% | 5.8% | 22.6% | 22.6% | 22.6% |
| NDA216962 | VYALEV | foscarbidopa | solution | 10162024 | -9.2% | -8.2% | 23.3% | 23.8% | 23.8% |
| NDA218347 | RINVOQ LQ | upadacitinib | solution | 4262024 | 17.1% | 19.7% | 20.8% | 50.3% | 50.3% |
| NDA214028 | VUITY | pilocarpine hydrochloride | solution/drops | 10282021 | 25.3% | 45.2% | 39.8% | 36.9% | 141.0% |
| NDA215206 | QULIPTA | atogepant | tablet | 9282021 | 26.7% | 54.5% | 40.2% | 53.6% | 149.2% |
| NDA215110 | MAVYRET | glecaprevir | pellets | 6102021 | -6.7% | 9.3% | 28.5% | 28.8% | 132.7% |
| NDA213388 | ORIAHNN (COPACKAGED) | elagolix sodium,estradiol,norethindrone acetate | capsule | 5292020 | 2.9% | 16.1% | 28.3% | 77.3% | 206.6% |
| NDA211911 | DURYSTA | bimatoprost | implant | 3042020 | 0.5% | 5.2% | 21.3% | 80.9% | 214.3% |
| NDA211765 | UBRELVY | ubrogepant | tablet | 12232019 | -27.6% | 10.9% | 20.2% | 61.8% | 223.9% |
| NDA211675 | RINVOQ | upadacitinib | tablet, extended release | 8162019 | 39.6% | 50.1% | 55.9% | 100.4% | 360.3% |
| ... | |||||||||
Segment Financials
Revenue by Segment| $ Mil | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|
| Humira | 14,404 | 21,237 | 20,694 | 19,832 | 19,169 |
| Skyrizi | 7,763 | 5,165 | 2,939 | 1,590 | 355 |
| Rinvoq | 3,969 | 2,522 | 1,651 | 731 | 47 |
| Imbruvica | 3,596 | 4,568 | 5,408 | 5,314 | 4,674 |
| All other | 3,035 | 4,137 | 5,019 | 2,923 | 2,068 |
| Botox Therapeutic | 2,991 | 2,719 | 2,451 | 1,387 | |
| Vraylar | 2,759 | 2,038 | 1,728 | 951 | |
| Botox Cosmetic | 2,682 | 2,615 | 2,232 | 1,112 | |
| Venclexta | 2,288 | 2,009 | 1,820 | 1,337 | 792 |
| Mavyret | 1,430 | 1,541 | 1,710 | 1,830 | 2,893 |
| Juvederm Collection | 1,378 | 1,428 | 1,535 | 718 | |
| Creon | 1,268 | 1,278 | 1,191 | 1,114 | 1,041 |
| Other Aesthetics | 1,234 | 1,290 | 1,466 | 760 | |
| Linzess/Constella | 1,108 | 1,035 | 1,038 | 667 | |
| Ubrelvy | 815 | 680 | 552 | 125 | |
| Other Eye Care | 803 | 747 | 1,169 | 693 | |
| Ozurdex | 472 | 428 | |||
| Duodopa | 468 | 458 | 511 | 494 | 461 |
| Restasis | 436 | 666 | 1,290 | 787 | |
| Lumigan/Ganfort | 432 | 514 | 579 | 378 | |
| Qulipta | 408 | 158 | |||
| Other Neuroscience | 276 | 475 | 685 | 539 | |
| Alphagan/Combigan | 272 | 346 | 529 | 326 | |
| Epkinly | 31 | 0 | |||
| Elahere | 0 | ||||
| Lo Loestrin | 356 | ||||
| Lupron | 752 | 887 | |||
| Orilissa/Oriahnn | 125 | 93 | |||
| Other Women's Health | 192 | ||||
| Synthroid | 771 | 786 | |||
| Total | 54,318 | 58,054 | 56,197 | 45,804 | 33,266 |
Price Behavior
Price Behavior
| Market Price | $227.91 | |
| Market Cap ($ Bil) | 403.2 | |
| First Trading Date | 01/02/2013 | |
| Distance from 52W High | -6.1% | |
| 50 Days | 200 Days | |
| DMA Price | $226.63 | $203.59 |
| DMA Trend | up | up |
| Distance from DMA | 0.6% | 11.9% |
| 3M | 1YR | |
| Volatility | 26.4% | 26.0% |
| Downside Capture | 17.93 | 20.77 |
| Upside Capture | 30.49 | 46.40 |
| Correlation (SPY) | 2.8% | 30.8% |
ABBV Betas & Captures as of 11/30/2025
[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
| 1M | 2M | 3M | 6M | 1Y | 3Y | |
|---|---|---|---|---|---|---|
| Beta | -0.24 | -0.10 | 0.05 | 0.08 | 0.40 | 0.31 |
| Up Beta | -0.68 | -0.07 | -0.02 | 0.03 | 0.31 | 0.31 |
| Down Beta | 0.43 | -0.16 | -0.19 | -0.17 | 0.66 | 0.52 |
| Up Capture | -25% | -12% | 37% | 41% | 30% | 7% |
| Bmk +ve Days | 12 | 25 | 38 | 73 | 141 | 426 |
| Stock +ve Days | 10 | 18 | 31 | 67 | 130 | 399 |
| Down Capture | -24% | -8% | -2% | -13% | 26% | 31% |
| Bmk -ve Days | 7 | 16 | 24 | 52 | 107 | 323 |
| Stock -ve Days | 9 | 23 | 31 | 57 | 117 | 350 |
[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
| Comparison of ABBV With Other Asset Classes (Last 1Y) | |||||||
|---|---|---|---|---|---|---|---|
| ABBV | Sector ETF | Equity | Gold | Commodities | Real Estate | Bitcoin | |
| Annualized Return | 34.5% | 13.6% | 14.7% | 67.3% | 6.8% | -0.5% | -16.6% |
| Annualized Volatility | 26.0% | 17.3% | 19.7% | 19.3% | 15.2% | 17.6% | 35.4% |
| Sharpe Ratio | 1.10 | 0.57 | 0.57 | 2.54 | 0.23 | -0.18 | -0.25 |
| Correlation With Other Assets | 68.4% | 31.2% | 1.4% | 3.8% | 49.5% | 3.8% | |
ETFs used for asset classes: Sector ETF = XLV, Equity = SPY, Gold = GLD, Commodities = DBC, Real Estate = VNQ, and Bitcoin = BTCUSD
Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 5-Year Data
| Comparison of ABBV With Other Asset Classes (Last 5Y) | |||||||
|---|---|---|---|---|---|---|---|
| ABBV | Sector ETF | Equity | Gold | Commodities | Real Estate | Bitcoin | |
| Annualized Return | 21.6% | 8.7% | 15.0% | 18.9% | 11.8% | 5.1% | 35.8% |
| Annualized Volatility | 22.4% | 14.5% | 17.1% | 15.5% | 18.7% | 18.9% | 48.9% |
| Sharpe Ratio | 0.84 | 0.42 | 0.71 | 0.98 | 0.51 | 0.18 | 0.63 |
| Correlation With Other Assets | 57.6% | 27.4% | 4.8% | 7.8% | 29.5% | 4.1% | |
ETFs used for asset classes: Sector ETF = XLV, Equity = SPY, Gold = GLD, Commodities = DBC, Real Estate = VNQ, and Bitcoin = BTCUSD
Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 10-Year Data
| Comparison of ABBV With Other Asset Classes (Last 10Y) | |||||||
|---|---|---|---|---|---|---|---|
| ABBV | Sector ETF | Equity | Gold | Commodities | Real Estate | Bitcoin | |
| Annualized Return | 20.1% | 10.0% | 14.9% | 14.9% | 6.7% | 5.5% | 69.9% |
| Annualized Volatility | 26.0% | 16.7% | 18.0% | 14.8% | 17.6% | 20.8% | 55.8% |
| Sharpe Ratio | 0.73 | 0.50 | 0.71 | 0.84 | 0.30 | 0.23 | 0.90 |
| Correlation With Other Assets | 63.8% | 43.4% | -0.4% | 15.0% | 35.7% | 4.7% | |
ETFs used for asset classes: Sector ETF = XLV, Equity = SPY, Gold = GLD, Commodities = DBC, Real Estate = VNQ, and Bitcoin = BTCUSD
Smart multi-asset allocation framework can stack odds in your favor. Learn How
Returns Analyses
Earnings Returns History
Expand for More| Forward Returns | |||
|---|---|---|---|
| Earnings Date | 1D Returns | 5D Returns | 21D Returns |
| 10/3/2025 | -1.6% | -0.7% | -8.7% |
| 7/3/2025 | -1.6% | 0.9% | 4.3% |
| 4/3/2025 | -7.3% | -13.6% | -1.9% |
| 1/6/2025 | -0.3% | -2.5% | 8.2% |
| 10/3/2024 | -0.6% | -0.6% | 5.0% |
| 7/3/2024 | -1.3% | 1.3% | 15.4% |
| 4/3/2024 | -5.3% | -4.7% | -8.5% |
| 1/5/2024 | -0.4% | 1.1% | 7.9% |
| ... | |||
| SUMMARY STATS | |||
| # Positive | 9 | 13 | 15 |
| # Negative | 16 | 12 | 10 |
| Median Positive | 2.8% | 2.5% | 7.9% |
| Median Negative | -1.4% | -2.4% | -5.9% |
| Max Positive | 5.9% | 16.1% | 29.6% |
| Max Negative | -7.3% | -13.6% | -12.0% |
SEC Filings
Expand for More| Report Date | Filing Date | Filing |
|---|---|---|
| 9302025 | 11042025 | 10-Q 9/30/2025 |
| 6302025 | 8042025 | 10-Q 6/30/2025 |
| 3312025 | 5092025 | 10-Q 3/31/2025 |
| 12312024 | 2142025 | 10-K 12/31/2024 |
| 9302024 | 11042024 | 10-Q 9/30/2024 |
| 6302024 | 8072024 | 10-Q 6/30/2024 |
| 3312024 | 5032024 | 10-Q 3/31/2024 |
| 12312023 | 2202024 | 10-K 12/31/2023 |
| 9302023 | 11062023 | 10-Q 9/30/2023 |
| 6302023 | 8072023 | 10-Q 6/30/2023 |
| 3312023 | 5052023 | 10-Q 3/31/2023 |
| 12312022 | 2172023 | 10-K 12/31/2022 |
| 9302022 | 11042022 | 10-Q 9/30/2022 |
| 6302022 | 8042022 | 10-Q 6/30/2022 |
| 3312022 | 5062022 | 10-Q 3/31/2022 |
| 12312021 | 2182022 | 10-K 12/31/2021 |
Insider Activity
Expand for More| Owner | Title | Filing Date | Action | Price | Shares | TransactedValue | Value ofHeld Shares | Form | |
|---|---|---|---|---|---|---|---|---|---|
| 0 | Donoghoe Nicholas | EVP, CHIEF BUS/STRAT OFFICER | 8072025 | Sell | 198.27 | 3,234 | 641,239 | 13,543,427 | Form |
| 1 | Reents Scott T | EVP, CHIEF FINANCIAL OFFICER | 3182025 | Sell | 212.34 | 17,644 | 3,746,527 | 2,458,260 | Form |
| 2 | Buckbee Kevin K | SVP, CONTROLLER | 2282025 | Sell | 203.40 | 2,684 | 545,926 | 2,572,196 | Form |
| 3 | RICHMOND TIMOTHY J. | EVP, CHIEF HR OFFICER | 2282025 | Sell | 202.06 | 1,400 | 282,884 | 10,222,417 | Form |
| 4 | Siatis Perry C | EVP, GC AND SECRETARY | 2242025 | Sell | 197.40 | 1,784 | 352,162 | 5,206,425 | Form |
Industry Resources
External Quote Links
| Y Finance | Barrons |
| TradingView | Morningstar |
| SeekingAlpha | ValueLine |
| Motley Fool | Robinhood |
| CNBC | Etrade |
| MarketWatch | Unusual Whales |
| YCharts | Perplexity Finance |
| FinViz |
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