Inspire Medical Systems (INSP)


Market Price (9/16/2026): $74.64 | Market Cap: $2.2 BilSector: Health Care | Industry: Health Care Equipment

Inspire Medical Systems (INSP)


Market Price (9/16/2026): $74.64
Market Cap: $2.2 Bil
Sector: Health Care
Industry: Health Care Equipment

Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.

0

Attractive yield
Total YieldTotal Yield = Earnings Yield + Dividend Yield, Earnings Yield = Net Income / Market Cap Dividend Yield = Total Dividends / Market Cap is 6.3%, FCF Yield is 5.5%

Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -14%

Attractive cash flow generation
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 17%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 13%

Megatrend and thematic drivers
Megatrends include Precision Medicine, Digital Health & Telemedicine, and Aging Population & Chronic Disease. Themes include Targeted Therapies, Show more.

Weak multi-year price returns
2Y Excs Rtn is -104%, 3Y Excs Rtn is -139%

Meaningful short interest
Short Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 13%

Expensive valuation multiples
P/EBITPrice/EBIT or Price/(Operating Income) ratio is 34x

Weak revenue growth
Rev Chg QQuarterly Revenue Change % is -7.6%

Significant share based compensation
SBC/Rev LTMShare Based Compensation / Revenue (Sales), Last Twelve Months (LTM) is 13%

Key risks
INSP key risks include [1] execution failures and legal challenges from its Inspire V product launch, Show more.

0 Attractive yield
Total YieldTotal Yield = Earnings Yield + Dividend Yield, Earnings Yield = Net Income / Market Cap Dividend Yield = Total Dividends / Market Cap is 6.3%, FCF Yield is 5.5%
1 Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -14%
2 Attractive cash flow generation
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 17%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 13%
3 Megatrend and thematic drivers
Megatrends include Precision Medicine, Digital Health & Telemedicine, and Aging Population & Chronic Disease. Themes include Targeted Therapies, Show more.
4 Weak multi-year price returns
2Y Excs Rtn is -104%, 3Y Excs Rtn is -139%
5 Meaningful short interest
Short Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 13%
6 Expensive valuation multiples
P/EBITPrice/EBIT or Price/(Operating Income) ratio is 34x
7 Weak revenue growth
Rev Chg QQuarterly Revenue Change % is -7.6%
8 Significant share based compensation
SBC/Rev LTMShare Based Compensation / Revenue (Sales), Last Twelve Months (LTM) is 13%
9 Key risks
INSP key risks include [1] execution failures and legal challenges from its Inspire V product launch, Show more.

INSP in ETFs

Weight = INSP's share of each fund

VTI0.00%
ITOT0.00%
IWM0.06%
IJR0.08%
VB0.02%
SLYG0.21%
IJT0.16%
IWO0.11%
+8 more covered ETFs

Valuation & Metrics

Price Chart

Why The Stock Moved

Qualitative Assessment

AI Analysis | Feedback

Updated on 9/11/2026

Inspire Medical Systems (INSP) stock has gained about 80% since 5/31/2026 because of the following key factors:

1. Strong Fiscal Q2 2026 Performance and Upbeat Guidance.

Inspire Medical Systems reported robust financial results for fiscal Q2 2026, which ended June 30, 2026. The company announced an adjusted diluted EPS of $0.14, significantly surpassing the consensus estimate of a loss of $0.24 per share. Additionally, revenue reached $200.6 million, exceeding analysts' expectations of $194.72 million. Following these strong results, management raised its full-year 2026 revenue guidance to a range of $835 million to $875 million and adjusted diluted EPS guidance to between $1.05 and $1.45. This positive outlook signaled an improving trajectory for the company's financial health.

2. Improving Reimbursement Environment and Catalysts.

A significant factor contributing to the stock's upward trend was the improving clarity and outlook regarding reimbursement. While the company initially faced challenges in its coding and reimbursement environment earlier in 2026, management indicated that prior authorization trends were improving, signaling a recovery in the second half of 2026. Furthermore, Stifel's analysis after the June Sleep conference suggested that the worst of the reimbursement volatility was over, with "green shoots starting to emerge". A key catalyst identified was the anticipated increase of approximately $10,000 per procedure in Medicare reimbursement for hospitals and surgical centers starting in 2026, which is crucial as Medicare accounts for 25-30% of Inspire's patient mix.

Show more
Updated on 9/11/2026

Inspire Medical Systems (INSP) stock has gained about 80% since 5/31/2026 because of the following key factors:

1. Strong Fiscal Q2 2026 Performance and Upbeat Guidance.

Inspire Medical Systems reported robust financial results for fiscal Q2 2026, which ended June 30, 2026. The company announced an adjusted diluted EPS of $0.14, significantly surpassing the consensus estimate of a loss of $0.24 per share. Additionally, revenue reached $200.6 million, exceeding analysts' expectations of $194.72 million. Following these strong results, management raised its full-year 2026 revenue guidance to a range of $835 million to $875 million and adjusted diluted EPS guidance to between $1.05 and $1.45. This positive outlook signaled an improving trajectory for the company's financial health.

2. Improving Reimbursement Environment and Catalysts.

A significant factor contributing to the stock's upward trend was the improving clarity and outlook regarding reimbursement. While the company initially faced challenges in its coding and reimbursement environment earlier in 2026, management indicated that prior authorization trends were improving, signaling a recovery in the second half of 2026. Furthermore, Stifel's analysis after the June Sleep conference suggested that the worst of the reimbursement volatility was over, with "green shoots starting to emerge". A key catalyst identified was the anticipated increase of approximately $10,000 per procedure in Medicare reimbursement for hospitals and surgical centers starting in 2026, which is crucial as Medicare accounts for 25-30% of Inspire's patient mix.

3. Introduction of Strategic Growth Plan "Project Horizon".

On August 3, 2026, coinciding with its fiscal Q2 earnings, Inspire Medical Systems unveiled "Project Horizon," a strategic growth plan designed to enhance financial flexibility and accelerate growth. This initiative aims to unlock and redeploy approximately $30 million in annualized investment capacity towards targeted growth initiatives by aligning resources and streamlining the organization. This strategic move was perceived positively by investors, as it demonstrated a proactive approach to optimizing operations and fostering future expansion.

4. Positive Analyst Sentiment and Upgraded Price Targets.

Following the strong fiscal Q2 2026 results and strategic announcements, several prominent equity research firms upgraded their ratings and raised price targets for Inspire Medical Systems. Oppenheimer, for instance, upgraded the stock from "market perform" to "outperform" and set an $85.00 price objective on August 4th. Mizuho also lifted its price objective from $55.00 to $65.00 with an "outperform" rating, and Zacks Research upgraded the stock from "hold" to "strong-buy" on August 17th. Most recently, on September 11, 2026, Stifel raised its price target to $80 from $75 while maintaining a Buy rating. This wave of positive analyst revisions contributed to increased investor confidence and buying interest.

5. Enhanced Product Mix with Inspire V System.

The successful adoption and increased sales mix of the company's fifth-generation Inspire V system played a role in improving profitability. In fiscal Q2 2026, the higher gross margin of the Inspire V system, compared to the Inspire IV system, led to a 150 basis point increase in gross margin, reaching 85.5%. The Inspire V system represented the majority of implants year-to-date in 2026, indicating strong market acceptance and a favorable shift in product mix contributing to healthier margins.

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Stock Movement Drivers

Fundamental Drivers

The 80.4% change in INSP stock from 5/31/2026 to 9/15/2026 was primarily driven by a 76.0% change in the company's P/E Multiple.
(LTM values as of)53120269152026Change
Stock Price ($)41.3674.6080.4%
Change Contribution By: 
Total Revenues ($ Mil)915899-1.8%
Net Income Margin (%)14.3%15.0%4.9%
P/E Multiple9.115.976.0%
Shares Outstanding (Mil)2929-0.5%
Cumulative Contribution80.4%

LTM = Last Twelve Months as of date shown

Market Drivers

5/31/2026 to 9/15/2026
ReturnCorrelation
INSP80.4% 
Market (SPY)0.1%24.9%
Sector (XLV)12.2%19.9%

Fundamental Drivers

The 15.6% change in INSP stock from 2/28/2026 to 9/15/2026 was primarily driven by a 24.1% change in the company's P/E Multiple.
(LTM values as of)22820269152026Change
Stock Price ($)64.5174.6015.6%
Change Contribution By: 
Total Revenues ($ Mil)912899-1.5%
Net Income Margin (%)15.9%15.0%-5.8%
P/E Multiple12.815.924.1%
Shares Outstanding (Mil)29290.4%
Cumulative Contribution15.6%

LTM = Last Twelve Months as of date shown

Market Drivers

2/28/2026 to 9/15/2026
ReturnCorrelation
INSP15.6% 
Market (SPY)10.7%16.5%
Sector (XLV)5.1%26.9%

Fundamental Drivers

The -20.4% change in INSP stock from 8/31/2025 to 9/15/2026 was primarily driven by a -69.4% change in the company's P/E Multiple.
(LTM values as of)83120259152026Change
Stock Price ($)93.6974.60-20.4%
Change Contribution By: 
Total Revenues ($ Mil)8618994.3%
Net Income Margin (%)6.2%15.0%143.6%
P/E Multiple52.015.9-69.4%
Shares Outstanding (Mil)30292.3%
Cumulative Contribution-20.4%

LTM = Last Twelve Months as of date shown

Market Drivers

8/31/2025 to 9/15/2026
ReturnCorrelation
INSP-20.4% 
Market (SPY)18.4%18.7%
Sector (XLV)23.6%19.8%

Fundamental Drivers

The -67.1% change in INSP stock from 8/31/2023 to 9/15/2026 was primarily driven by a -81.0% change in the company's P/S Multiple.
(LTM values as of)83120239152026Change
Stock Price ($)226.8874.60-67.1%
Change Contribution By: 
Total Revenues ($ Mil)52689970.8%
P/S Multiple12.62.4-81.0%
Shares Outstanding (Mil)29291.4%
Cumulative Contribution-67.1%

LTM = Last Twelve Months as of date shown

Market Drivers

8/31/2023 to 9/15/2026
ReturnCorrelation
INSP-67.1% 
Market (SPY)74.1%24.2%
Sector (XLV)31.8%22.6%

Return vs. Risk

Price Returns Compared

 202120222023202420252026Total [1]
Returns
INSP Return22%9%-19%-9%-50%-19%-60%
Peers Return16%-14%-13%42%0%-7%15%
S&P 500 Return27%-19%24%23%16%11%103%

Monthly Win Rates [3]
INSP Win Rate58%58%50%50%17%56% 
Peers Win Rate50%50%48%53%47%38% 
S&P 500 Win Rate75%42%67%75%67%44% 

Max Drawdowns [4]
INSP Max Drawdown-34%-45%-62%-50%-67%-60% 
Peers Max Drawdown-30%-42%-46%-23%-35%-29% 
S&P 500 Max Drawdown-5%-25%-10%-8%-19%-9% 


[1] Cumulative total returns since the beginning of 2021
[2] Peers: PEN, GMED, NVCR, ABT, ISRG.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 9/15/2026 (YTD)

How Low Can It Go

EventINSPS&P 500
2023 SVB Regional Banking Crisis
  % Loss-16.4%-6.7%
  % Gain to Breakeven19.7%7.1%
  Time to Breakeven17 days31 days
2022 Inflation Shock & Fed Tightening
  % Loss-38.0%-24.5%
  % Gain to Breakeven61.3%32.4%
  Time to Breakeven205 days427 days
2020 COVID-19 Crash
  % Loss-49.2%-33.7%
  % Gain to Breakeven96.8%50.9%
  Time to Breakeven58 days140 days

Compare to PEN, GMED, NVCR, ABT, ISRG

In The Past

Inspire Medical Systems's stock fell -4.2% during the 2024 Yen Carry Trade Unwind. Such a loss loss requires a 4.4% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

EventINSPS&P 500
2022 Inflation Shock & Fed Tightening
  % Loss-38.0%-24.5%
  % Gain to Breakeven61.3%32.4%
  Time to Breakeven205 days427 days
2020 COVID-19 Crash
  % Loss-49.2%-33.7%
  % Gain to Breakeven96.8%50.9%
  Time to Breakeven58 days140 days

Compare to PEN, GMED, NVCR, ABT, ISRG

In The Past

Inspire Medical Systems's stock fell -4.2% during the 2024 Yen Carry Trade Unwind. Such a loss loss requires a 4.4% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

About Inspire Medical Systems (INSP)

Inspire Medical Systems (INSP) is a medical technology company focused on developing and commercializing minimally invasive solutions for patients with obstructive sleep apnea (OSA). Since its incorporation in 2007, the company has positioned itself as an innovator in addressing this common sleep disorder, offering an alternative to traditional treatments.

The company's core product is the Inspire system, a neurostimulation technology that provides a safe and effective treatment for moderate to severe OSA. This implanted system works by gently stimulating the hypoglossal nerve to keep the airway open during sleep. Inspire Medical Systems is also engaged in developing a novel, closed-loop solution designed to continuously monitor a patient's breathing and deliver precisely timed hypoglossal nerve stimulation.

Inspire Medical Systems serves patients with moderate to severe obstructive sleep apnea. Its market reach spans both the United States and international geographies, providing a critical treatment option for individuals who may not tolerate or benefit from other OSA therapies.

AI Analysis | Feedback

Here are 1-2 brief analogies to describe Inspire Medical Systems (INSP):

  • Like a specialized Medtronic focused on treating sleep apnea.
  • The Cochlear Limited of sleep apnea treatment.

AI Analysis | Feedback

  • Inspire system: A neurostimulation technology that provides a safe and effective treatment for moderate to severe obstructive sleep apnea (OSA).
  • Novel closed-loop solution: A developing technology designed to continuously monitor a patient's breathing and deliver mild hypoglossal nerve stimulation to maintain an open airway.

AI Analysis | Feedback

Inspire Medical Systems (INSP) sells its Inspire system primarily to healthcare providers and facilities, which then use the technology to treat individual patients with obstructive sleep apnea (OSA).

The major categories of customers for Inspire Medical Systems are:

  1. Hospitals: Large medical institutions that perform a wide range of surgical procedures and treatments, including those for sleep disorders.
  2. Ambulatory Surgical Centers (ASCs): Facilities where surgical procedures that do not require an overnight hospital stay are performed, often offering a more cost-effective setting for device implantation.
  3. Specialized ENT (Ear, Nose, and Throat) Practices and Sleep Clinics: Medical practices and centers that specialize in the diagnosis and treatment of conditions related to the ear, nose, throat, and sleep disorders, where Inspire system implantations are performed.

AI Analysis | Feedback

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AI Analysis | Feedback

The management team of Inspire Medical Systems (INSP) consists of the following members:

Timothy P. Herbert, Chairman, President and Chief Executive Officer

Mr. Herbert is the founder of Inspire Medical Systems, establishing the company in 2007. He has served as President and CEO since its inception and assumed the role of Chairman of the Board in May 2024. Before founding Inspire, Mr. Herbert spent 11 years, from 1996 to 2007, at Medtronic plc, where he held various management positions across product development, clinical research, sales, marketing, and healthcare reimbursement. He was instrumental in developing Inspire's core neurostimulation technology and leading its capital formation strategies. Mr. Herbert holds a B.S. in Electrical Engineering from North Dakota State University and an M.B.A. from the University of St. Thomas.

Matt Osberg, Executive Vice President and Chief Financial Officer

Mr. Osberg was appointed Executive Vice President and Chief Financial Officer, effective January 19, 2026. He brings over 20 years of experience in financial leadership. Prior to joining Inspire, Mr. Osberg served as Executive Vice President and CFO at Apogee Enterprises, Inc. His career also includes CFO positions at Helen of Troy, Ltd. and various finance leadership roles at Best Buy, Inc. He began his career at Ernst & Young LLP. Mr. Osberg has a background primarily outside of the medical technology industry.

Bryan K. Phillips, SVP, General Counsel, Chief Compliance Officer and Corporate Secretary

Mr. Phillips joined Inspire Medical Systems in January 2021. Before his role at Inspire, he served as Chief Legal Officer at Cerevel Therapeutics Holdings, Inc. from 2019 to 2021. He also spent 14 years at Surmodics, Inc., a publicly traded medical technology company, holding various positions including Senior Vice President, Legal and Human Resources, General Counsel, and Secretary. Earlier in his career, he was patent counsel at Guidant Corporation's Cardiac Rhythm Management Group (now part of Boston Scientific) and began his legal career at a Minneapolis-based intellectual property law firm. Mr. Phillips holds a B.S. in Mechanical Engineering from the University of Kansas and a J.D. from the University of Minnesota Law School.

Carlton W. Weatherby, Chief Strategy and Growth Officer

Mr. Weatherby has been Inspire Medical Systems' Chief Strategy and Growth Officer since January 2024. Prior to joining Inspire, he served as the Chief Commercial Officer at AliveCor, Inc., a medical device company, from July 2021 to December 2023. He also held roles as President, Commercial Operations, and Chief Commercial Officer at Intersect ENT, Inc., a medical technology company, from October 2017 to July 2021, and as Vice President, Sales & Marketing, ENT at Smith & Nephew plc from January 2013 to October 2017. Mr. Weatherby received his B.S. in Biology from West Chester University.

John C. Rondoni, Chief Product & Innovation Officer

Mr. Rondoni has served as Inspire Medical Systems' Chief Product & Innovation Officer since January 2025. He has been with Inspire since January 2010, holding various positions including Vice President of Product Development, Operations & Quality. Before joining Inspire, Mr. Rondoni spent 11 years at Medtronic, Inc., where he held leadership roles in research and development. He began his career at Boston Scientific, Inc. in research and development. Mr. Rondoni holds a B.S. in Bioengineering from Syracuse University and an M.S. in Biomedical Engineering from the University of Alabama, Birmingham.

AI Analysis | Feedback

The key risks to Inspire Medical Systems (INSP) primarily revolve around reimbursement challenges, increasing competition, and operational hurdles related to product launches.

  1. Reimbursement Uncertainty and Operational Challenges with New Product Launches: Inspire Medical Systems faces significant risks due to evolving and uncertain reimbursement policies, particularly concerning its latest device, Inspire V. There have been issues with CMS coding, including a shift from CPT code 64568 to 64582, which could reduce professional fees. A notable concern was the reversal of a key Medicare reimbursement code by administrative contractors, which negatively impacted reimbursement rates and created uncertainty about future revenue growth. Furthermore, the company is facing securities fraud lawsuits alleging that it concealed critical operational failures during the Inspire V launch, such as incomplete training and onboarding for treatment centers, delays in software updates for Medicare claims processing, and an excess inventory of the older Inspire IV device, all of which led to a significant reduction in 2025 earnings guidance.

  2. Increasing Competition from Alternative Therapies and Competitors: The market for obstructive sleep apnea (OSA) treatment is becoming more competitive. Inspire faces competition from established players like ResMed, which dominates the CPAP machine market (the standard first-line treatment for OSA). Moreover, emerging alternative therapies pose a threat, including oral appliance therapies, new pharmaceutical treatments like GLP-1 drugs (e.g., Lilly's Tirzepatide, which can improve sleep quality in obese patients), and Apnimed's AD109. These alternatives could potentially dilute Inspire's market opportunity, especially for its third-line treatment offering.

  3. Healthcare Provider Capacity Constraints: The growth and adoption of Inspire's hypoglossal nerve stimulation therapy are heavily reliant on ear, nose, and throat (ENT) surgeons who perform the implantation procedures. A potential constraint on the company's growth is the capacity of the ENT workforce. If the growth in the number of ENT surgeons or their availability to perform these procedures does not keep pace with the demand for Inspire's device, it could cap the company's growth potential.

AI Analysis | Feedback

The emergence of competing hypoglossal nerve stimulation devices represents a clear emerging threat. Specifically, Nyxoah's Genio system, which received FDA approval in August 2023, is a direct competitor to Inspire's core technology. Nyxoah's system is also designed for obstructive sleep apnea and offers a battery-free, leadless, and minimally invasive solution, which could differentiate it in the market and challenge Inspire's market share and first-mover advantage.

AI Analysis | Feedback

Inspire Medical Systems (INSP) addresses a significant market for its neurostimulation technology designed for patients with obstructive sleep apnea (OSA). The company's main product, the Inspire system, provides a minimally invasive solution for individuals with moderate to severe OSA, particularly those who cannot tolerate continuous positive airway pressure (CPAP) machines. The addressable market for Inspire's therapy is estimated to be over $10 billion in the U.S. alone. This market primarily targets the subset of patients with OSA who are unable to use or adhere to traditional CPAP therapy. Approximately 700,000 patients annually fail to comply with CPAP therapy, with Inspire estimating that about 500,000 of these patients are eligible for their therapy, creating a substantial addressable market. In broader terms, obstructive sleep apnea affects 17 million Americans and an additional 83 million people globally. The U.S. sleep apnea implants market, which includes Inspire's technology, was valued at USD 840 million in 2024 and is projected to grow to USD 4.3 billion by 2034, exhibiting a compound annual growth rate (CAGR) of 17.4% from 2025 to 2034. The global sleep apnea devices market was valued at USD 10.30 billion in 2025 and is projected to reach USD 22.87 billion by 2034. North America held the largest share of this market, accounting for 49.55% in 2025.

AI Analysis | Feedback

Inspire Medical Systems (INSP) is expected to drive future revenue growth over the next 2-3 years through several key initiatives and market dynamics:

  1. Successful launch and adoption of new product generations: The company anticipates continued revenue growth from the successful launch and strong acceptance of its fifth-generation Inspire V system, which was a significant contributor to revenue in late 2025 and is expected to fuel momentum in 2026.
  2. Increased utilization at existing implanting centers: A primary driver of U.S. revenue growth has been, and is expected to continue to be, higher utilization of the Inspire therapy at already established medical centers.
  3. Expansion of implanting centers and sales territories: Inspire Medical Systems consistently focuses on activating new U.S. medical centers and expanding its sales organization by creating new sales territories, thereby increasing market penetration and access to its therapy.
  4. Direct-to-consumer marketing programs: The company's ongoing direct-to-consumer marketing initiatives are expected to continue raising awareness and driving patient interest, contributing to overall demand and revenue growth.
  5. Potential positive reimbursement developments: Inspire Medical Systems sees potential upside from ongoing reimbursement developments, although these have not yet been fully factored into current growth forecasts. Recent clarifications regarding CPT codes for the Inspire V procedure could influence future revenue.

AI Analysis | Feedback

Share Repurchases

  • Inspire Medical Systems' Board of Directors authorized a share repurchase program of up to $200 million on August 11, 2025, which is set to expire on August 7, 2027.
  • In 2025, the company completed $175 million in share repurchases.
  • Previously, on August 6, 2024, the Board authorized the repurchase of up to $150 million of common stock, a program that was the first of its kind for Inspire and set to expire on August 5, 2026.

Share Issuance

  • As of April 30, 2025, Inspire Medical Systems had 29,493,924 shares of common stock outstanding.
  • For 2026, the estimated weighted average diluted shares outstanding are approximately 29.4 million.
  • In February 2026, an executive acquired 2,196 shares through vested performance stock units, and another officer acquired 2,400 shares from similar vested units, along with 15,958 additional shares via a new stock award.

Capital Expenditures

  • For the upcoming year, 2026, Inspire Medical Systems anticipates capital expenditures to range between $45 million and $50 million.
  • The company made significant investments in 2025 to build its commercial infrastructure, increase patient marketing, and expand medical education expenses, particularly to support the U.S. launch of its Inspire V neurostimulation system.

Better Bets vs. Inspire Medical Systems (INSP)

Peer Outperformance in Health Care Equipment

INSP has trailed 78% of its 49 Health Care Equipment peers over 5Y. Among the peers that beat it are UFPT, ISRG and PEN. Health Care Equipment ranks 5th of 10 industries in Health Care by median 5Y return.
Share of Health Care Equipment constituents that INSP has outperformed, by holding period. Peers without a full price history over a given window are excluded from that window.
1Y
45%
of 55 industry peers · -7.6% return
3Y
13%
of 54 industry peers · -64.6% return
5Y
22%
of 49 industry peers · -69.5% return
Health Care Equipment peers with revenue growth within 4pp of INSP's that beat it on at least 2 of 3 windows, and by at least 20pp over 5Y. Growth is matched by construction, so the gap is largely a re-rating gap. The multiple column is the context for it.
Ticker Name Rev Growth 3Y Avg P/E 1Y3Y5Y 5Y Gap
INSP Inspire Medical Systems 20.2% 15.9x -7.6%-64.6%-69.5%
UFPT UFP Technologies 18.8% 29.5x 35.0%68.5%332.2% +402pp
ISRG Intuitive Surgical 18.4% 42.5x -13.1%27.6%9.4% +79pp
PEN Penumbra 17.1% 78.0x 21.0%19.0%9.3% +79pp
BSX Boston Scientific 16.2% 17.6x -56.1%-17.1%-2.3% +67pp
Price returns, excluding dividends. P/E shown for context only and not used for matching.
Median price return by industry across the Health Care sector, ranked by 5Y. Health Care Equipment is INSP's own industry. Use this to see which corners of the sector have carried the returns.
Industry Names 1Y med3Y med5Y med Top 3 by 5Y
Health Care Distributors 7 11.8%82.9%82.9% CAH 392% · MCK 344% · COR 174%
Managed Health Care 8 42.4%-0.4%7.2% OSCR 85% · HQY 56% · ELV 20%
Health Care Services 20 25.7%44.9%-0.2% HIMS 223% · RDNT 178% · DGX 76%
Health Care Facilities 24 5.6%6.5%-13.9% NHC 276% · THC 256% · ENSG 121%
Health Care Equipment ← 50 -2.8%-4.6%-23.3% POCI 10425% · UFPT 332% · GKOS 225%
Health Care Supplies 12 17.5%-10.5%-39.5% LNTH 293% · HAE 55% · MMSI 20%
Pharmaceuticals 62 -8.4%8.3%-40.9% LQDA 2380% · INDV 1129% · ETON 983%
Life Sciences Tools & Services 110 -2.0%-22.5%-70.2% SNWV 1578% · MEDP 236% · NTRA 191%
Health Care Technology 21 -25.1%-50.8%-79.7% SPOK 76% · HSTM 7% · VEEV -13%
Biotechnology 364 -1.4%-26.5%-80.1% DNTH 1425% · CELZ 1164% · ELVN 1094%
Median of constituents with a full price history over each window. Top names are unfiltered by size in this render.

Latest Trefis Analyses

Recent Active Movers

Peer Comparisons

Peers to compare with:

Financials

INSPPENGMEDNVCRABTISRGMedian
NameInspire .Penumbra Globus M.NovoCure Abbott L.Intuitiv. 
Mkt Price74.60318.4374.6916.15102.03377.1688.36
Mkt Cap2.212.510.11.9177.6133.611.3
Rev LTM8991,5053,14569946,58511,0342,325
Op Inc LTM54187674-1547,3463,451431
FCF LTM117216746-257,8243,223481
FCF 3Y Avg64163478-706,7511,879320
CFO LTM157278910-39,9053,706594
CFO 3Y Avg101202614-388,9472,732408

Growth & Margins

INSPPENGMEDNVCRABTISRGMedian
NameInspire .Penumbra Globus M.NovoCure Abbott L.Intuitiv. 
Rev Chg LTM4.3%17.6%19.7%11.0%8.1%20.7%14.3%
Rev Chg 3Y Avg20.2%17.1%47.0%11.3%5.1%18.4%17.7%
Rev Chg Q-7.6%14.9%5.9%15.6%13.0%18.5%14.0%
QoQ Delta Rev Chg LTM-1.8%3.5%1.4%3.7%3.2%4.3%3.3%
Op Inc Chg LTM30.7%17.6%93.7%10.6%-2.2%31.0%24.2%
Op Inc Chg 3Y Avg164.6%79.2%56.5%6.7%6.5%28.8%42.6%
Op Mgn LTM6.0%12.4%21.4%-22.1%15.8%31.3%14.1%
Op Mgn 3Y Avg2.9%10.5%14.0%-27.7%16.4%28.6%12.3%
QoQ Delta Op Mgn LTM0.4%-0.4%2.0%5.1%-1.3%0.8%0.6%
CFO/Rev LTM17.5%18.5%28.9%-0.4%21.3%33.6%19.9%
CFO/Rev 3Y Avg11.8%15.2%22.0%-6.6%20.5%28.8%17.9%
FCF/Rev LTM13.0%14.3%23.7%-3.6%16.8%29.2%15.6%
FCF/Rev 3Y Avg7.2%12.2%17.0%-11.8%15.5%18.9%13.9%

Valuation

INSPPENGMEDNVCRABTISRGMedian
NameInspire .Penumbra Globus M.NovoCure Abbott L.Intuitiv. 
Mkt Cap2.212.510.11.9177.6133.611.3
P/S2.48.33.22.73.812.13.5
P/Op Inc39.766.915.0-12.124.238.731.4
P/EBIT34.561.115.0-15.621.538.728.0
P/E15.978.018.8-12.632.742.525.8
P/CFO13.745.111.1-665.617.936.015.8
Total Yield6.3%1.3%5.3%-7.9%5.5%2.4%3.8%
Dividend Yield0.0%0.0%0.0%0.0%2.4%0.0%0.0%
FCF Yield 3Y Avg3.7%1.6%5.1%-3.7%3.6%1.2%2.6%
D/E0.00.00.00.10.20.00.0
Net D/E-0.1-0.0-0.0-0.10.2-0.0-0.0

Returns

INSPPENGMEDNVCRABTISRGMedian
NameInspire .Penumbra Globus M.NovoCure Abbott L.Intuitiv. 
1M Rtn30.6%-2.6%-13.1%-4.7%-8.3%-4.4%-4.6%
3M Rtn80.2%-0.0%-3.7%-7.7%13.4%-9.6%-1.8%
6M Rtn35.3%-5.8%-15.3%30.8%-6.6%-21.9%-6.2%
12M Rtn-7.6%21.0%28.2%27.0%-20.5%-13.1%6.7%
3Y Rtn-64.6%19.0%49.4%-16.3%6.7%27.6%12.9%
1M Excs Rtn33.2%-0.1%-10.5%-2.2%-5.7%-1.8%-2.0%
3M Excs Rtn81.0%-0.3%-3.8%-8.7%15.5%-9.9%-2.1%
6M Excs Rtn13.5%-18.5%-26.1%17.2%-19.2%-35.2%-18.9%
12M Excs Rtn-22.0%1.5%11.9%17.7%-37.2%-31.3%-10.2%
3Y Excs Rtn-137.0%-61.5%-23.3%-89.6%-62.4%-43.7%-61.9%

Comparison Analyses

null

Financials

Segment Financials

Revenue by Segment
$ Mil20252024202320222021
Inspire system912803625  
Single Segment   408233
Total912803625408233


Price Behavior

Price Behavior
Market Price$74.60 
Market Cap ($ Bil)2.2 
First Trading Date05/03/2018 
Distance from 52W High-48.2% 
   50 Days200 Days
DMA Price$58.45$65.73
DMA Trenddownup
Distance from DMA27.6%13.5%
 3M1YR
Volatility63.6%70.9%
Downside Capture-50.7795.47
Upside Capture271.9969.74
Correlation (SPY)29.3%19.3%
INSP Betas & Captures as of 8/31/2026

 1M2M3M6M1Y3Y
Beta5.642.621.160.721.061.08
Up Beta9.125.151.841.012.141.39
Down Beta-2.420.190.520.510.620.81
Up Capture594%364%231%47%35%31%
Bmk +ve Days10213268138427
Stock +ve Days10223564122365
Down Capture268%79%8%80%110%107%
Bmk -ve Days11213259113324
Stock -ve Days11202963128382

[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with INSP
INSP-6.8%70.8%0.18-
Sector ETF (XLV)23.1%16.1%1.1018.5%
Equity (SPY)16.3%12.8%0.9019.3%
Gold (GLD)17.6%29.3%0.559.6%
Commodities (DBC)48.6%20.6%1.82-1.7%
Real Estate (VNQ)5.3%13.5%0.1315.6%
Bitcoin (BTCUSD)-33.1%43.8%-0.7912.3%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 5-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with INSP
INSP-20.0%60.9%-0.12-
Sector ETF (XLV)5.9%15.2%0.2030.1%
Equity (SPY)12.4%17.2%0.5535.6%
Gold (GLD)18.7%18.8%0.806.1%
Commodities (DBC)11.7%19.5%0.475.9%
Real Estate (VNQ)0.8%18.9%-0.0628.6%
Bitcoin (BTCUSD)10.7%52.5%0.3819.9%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 10-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with INSP
INSP11.9%60.7%0.48-
Sector ETF (XLV)10.6%16.7%0.5138.0%
Equity (SPY)15.1%18.0%0.7140.9%
Gold (GLD)12.0%16.4%0.606.2%
Commodities (DBC)8.7%18.1%0.3911.3%
Real Estate (VNQ)4.6%20.7%0.1832.8%
Bitcoin (BTCUSD)63.4%66.2%1.0316.3%

Smart multi-asset allocation framework can stack odds in your favor. Learn How

Short Interest

Short Interest: As Of Date8312026
Short Interest: Shares Quantity3.7 Mil
Short Interest: % Change Since 8152026-16.4%
Average Daily Volume0.5 Mil
Days-to-Cover Short Interest7.5 days
Basic Shares Quantity28.8 Mil
Short % of Basic Shares12.7%

Earnings Returns History

Updated 9/3/2026
Expand for More
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
8/3/202622.8%14.4%17.8%
5/4/2026-12.0%-21.0%-26.3%
2/11/2026-12.5%-12.4%-14.1%
11/3/202515.3%16.8%90.0%
8/4/2025-32.4%-38.7%-34.1%
5/5/20252.0%-1.4%-13.1%
2/10/20251.7%-0.5%-10.2%
11/4/20243.3%4.8%2.2%
...
SUMMARY STATS   
# Positive13129
# Negative111215
Median Positive7.0%7.5%19.9%
Median Negative-12.0%-17.2%-13.2%
Max Positive31.8%39.1%90.0%
Max Negative-33.5%-38.7%-36.3%
Collapse to Preview
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
8/3/202622.8%14.4%17.8%
5/4/2026-12.0%-21.0%-26.3%
2/11/2026-12.5%-12.4%-14.1%
11/3/202515.3%16.8%90.0%
8/4/2025-32.4%-38.7%-34.1%
5/5/20252.0%-1.4%-13.1%
2/10/20251.7%-0.5%-10.2%
11/4/20243.3%4.8%2.2%
8/6/202428.1%30.7%34.2%
5/7/2024-33.5%-35.4%-36.3%
2/6/2024-10.5%-16.7%-8.9%
11/7/2023-19.7%-17.7%-0.5%
8/1/2023-4.5%-15.8%-18.3%
5/2/20237.0%12.0%17.5%
1/9/2023-1.5%4.2%1.2%
11/1/20227.5%5.4%24.7%
8/2/20220.7%-2.3%-11.7%
5/3/2022-3.1%-27.6%-13.2%
2/8/20222.0%0.0%-4.6%
11/2/2021-1.4%2.0%-18.2%
8/3/202112.8%0.6%19.9%
5/4/2021-12.6%-20.6%-26.8%
2/23/20214.9%9.5%-12.3%
11/2/202031.8%39.1%57.3%
SUMMARY STATS   
# Positive13129
# Negative111215
Median Positive7.0%7.5%19.9%
Median Negative-12.0%-17.2%-13.2%
Max Positive31.8%39.1%90.0%
Max Negative-33.5%-38.7%-36.3%

SEC Filings

Expand for More
Report DateFiling DateFiling
06/30/202608/03/202610-Q
03/31/202605/04/202610-Q
12/31/202502/13/202610-K
09/30/202511/03/202510-Q
06/30/202508/04/202510-Q
03/31/202505/05/202510-Q
12/31/202402/10/202510-K
09/30/202411/04/202410-Q
06/30/202408/06/202410-Q
03/31/202405/07/202410-Q
12/31/202302/09/202410-K
09/30/202311/07/202310-Q
06/30/202308/01/202310-Q
03/31/202305/02/202310-Q
12/31/202202/10/202310-K
09/30/202211/01/202210-Q
Collapse to Preview
Report DateFiling DateFiling
06/30/202608/03/202610-Q
03/31/202605/04/202610-Q
12/31/202502/13/202610-K
09/30/202511/03/202510-Q
06/30/202508/04/202510-Q
03/31/202505/05/202510-Q
12/31/202402/10/202510-K
09/30/202411/04/202410-Q
06/30/202408/06/202410-Q
03/31/202405/07/202410-Q
12/31/202302/09/202410-K
09/30/202311/07/202310-Q
06/30/202308/01/202310-Q
03/31/202305/02/202310-Q
12/31/202202/10/202310-K
09/30/202211/01/202210-Q
06/30/202208/02/202210-Q
03/31/202205/03/202210-Q
12/31/202102/15/202210-K
09/30/202111/02/202110-Q
06/30/202108/03/202110-Q
03/31/202105/04/202110-Q
12/31/202002/24/202110-K
09/30/202011/02/202010-Q
06/30/202008/04/202010-Q
03/31/202005/05/202010-Q
12/31/201902/25/202010-K
09/30/201911/05/201910-Q

Recent Forward Guidance

Updated 8/4/2026

Latest: Q2 2026 Earnings Reported 8/3/2026

Forward GuidanceGuidance Change
MetricSourceLowMidHigh% Chg% DeltaChangePrior
2026 RevenueReported835.00 Mil855.00 Mil875.00 Mil0.6% RaisedGuidance: 850.00 Mil for 2026
2026 Adjusted Operating MarginReported4.0%5.0%6.0% 2.0%RaisedGuidance: 3.0% for 2026
2026 Diluted EPSReported-0.42-0.120.17-136.2% LoweredGuidance: 0.34 for 2026
2026 Adjusted Diluted EPSReported1.051.251.4525.0% RaisedGuidance: 1 for 2026
2026 Capital ExpendituresReported35.00 Mil37.50 Mil40.00 Mil-11.8% LoweredGuidance: 42.50 Mil for 2026


Prior: Q1 2026 Earnings Reported 5/4/2026

Forward GuidanceGuidance Change
MetricSourceLowMidHigh% Chg% DeltaChangePrior
2026 RevenueReported825.00 Mil850.00 Mil875.00 Mil-12.8% LoweredGuidance: 975.00 Mil for 2026
2026 Adjusted Operating MarginReported2.0%3.0%4.0% -4.0%LoweredGuidance: 7.0% for 2026
2026 Diluted EPSReported0.070.340.62-77.3% LoweredGuidance: 1.52 for 2026
2026 Adjusted Diluted EPSReported0.7511.25-52.4% LoweredGuidance: 2.1 for 2026
2026 Capital ExpendituresReported40.00 Mil42.50 Mil45.00 Mil-10.5% LoweredGuidance: 47.50 Mil for 2026

Q4 2025 Earnings Reported 2/11/2026

Forward GuidanceGuidance Change
MetricSourceLowMidHigh% Chg% DeltaChangePrior
2026 RevenueReported950.00 Mil975.00 Mil1.00 Bil7.7% Higher NewGuidance: 905.00 Mil for 2025
2026 Revenue GrowthReported4.0%7.0%10.0% -5.5%Lower NewGuidance: 12.5% for 2025
2026 Adjusted Operating MarginReported6.0%7.0%8.0% -78.0%Lower NewGuidance: 85.0% for 2025
2026 Net Income per Diluted ShareReported1.231.521.8160.0% Higher NewGuidance: 0.95 for 2025
2026 Adjusted Net Income per Diluted ShareReported1.852.12.35121.1% Higher NewGuidance: 0.95 for 2025
2026 Capital ExpendituresReported45.00 Mil47.50 Mil50.00 Mil   

Q3 2025 Earnings Reported 11/3/2025

Forward GuidanceGuidance Change
MetricSourceLowMidHigh% Chg% DeltaChangePrior
2025 RevenueReported900.00 Mil905.00 Mil910.00 Mil0 AffirmedGuidance: 905.00 Mil for 2025
2025 Revenue GrowthReported12.0%12.5%13.0% 0AffirmedGuidance: 12.5% for 2025
2025 Gross ProfitCalculated756.00 Mil769.25 Mil782.60 Mil  Rev x Gross Margin
2025 Gross MarginReported84.0%85.0%86.0% 0AffirmedGuidance: 85.0% for 2025
2025 EPSReported0.90.951111.1%50.0%RaisedGuidance: 0.45 for 2025

Insider Activity

Updated 9/2/2026
Expand for More
#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Kelly, Jason PSee RemarksDirectSell811202659.5596357,3471,130,557Form
2Rondoni, JohnSee RemarksDirectSell519202643.282,641114,3021,175,701Form
3Rondoni, JohnSee RemarksDirectSell515202643.0170030,1071,281,956Form
4McCormick, ShawnDirectSell511202645.3169631,5361,255,631Form
5Rondoni, JohnSee RemarksDirectSell1122026100.0010910,9001,379,700Form
Collapse to Preview
#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Kelly, Jason PSee RemarksDirectSell811202659.5596357,3471,130,557Form
2Rondoni, JohnSee RemarksDirectSell519202643.282,641114,3021,175,701Form
3Rondoni, JohnSee RemarksDirectSell515202643.0170030,1071,281,956Form
4McCormick, ShawnDirectSell511202645.3169631,5361,255,631Form
5Rondoni, JohnSee RemarksDirectSell1122026100.0010910,9001,379,700Form
6McCormick, ShawnDirectSell12042025139.001,200166,8003,453,594Form
7McCormick, ShawnDirectSell12012025127.482,000254,9603,320,344Form
8Curet, MyriamDirectSell1124202577.284309260,032Form
9Curet, MyriamDirectSell11242025153.222306516,211Form
10Curet, MyriamDirectBuy11242025148.261148499,791Form
11Curet, MyriamDirectBuy11242025163.844655552,137Form
12Buchholz, RichardChief Financial OfficerDirectSell902202593.3911,0001,027,2904,190,129Form
Core Cache Last Updated: 9/15/2026