10x Genomics (TXG)


Market Price (9/6/2026): $62.7 | Market Cap: $8.2 BilSector: Health Care | Industry: Life Sciences Tools & Services

10x Genomics (TXG)


Market Price (9/6/2026): $62.7
Market Cap: $8.2 Bil
Sector: Health Care
Industry: Life Sciences Tools & Services

Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.

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Attractive cash flow generation
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 21%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 20%

Megatrend and thematic drivers
Megatrends include Biotechnology & Genomics, and Precision Medicine. Themes include Advanced Diagnostics, Personalized Diagnostics, Show more.

Trading close to highs
Dist 52W High is -3.8%, Dist 3Y High is -3.8%

Weak multi-year price returns
3Y Excs Rtn is -49%

Meaningful short interest
Short Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 12%

Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -92 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -15%

Expensive valuation multiples
P/CFOPrice/(Cash Flow from Operations). CFO is cash before capital expenditures. is 64x

Stock price has recently run up significantly
6M Rtn6 month market price return is 201%, 12M Rtn12 month market price return is 349%

Weak revenue growth
Rev Chg LTMRevenue Change % Last Twelve Months (LTM) is -4.3%, Rev Chg QQuarterly Revenue Change % is -13%

Significant share based compensation
SBC/Rev LTMShare Based Compensation / Revenue (Sales), Last Twelve Months (LTM) is 16%

Valuation getting more expensive
P/S 6M Chg %Price/Sales change over 6 months. Declining P/S indicates valuation has become less expensive. is 210%

Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -5.2%

Key risks
TXG key risks include [1] a sharp decline in instrument revenue due to tightening research budgets, Show more.

0 Attractive cash flow generation
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 21%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 20%
1 Megatrend and thematic drivers
Megatrends include Biotechnology & Genomics, and Precision Medicine. Themes include Advanced Diagnostics, Personalized Diagnostics, Show more.
2 Trading close to highs
Dist 52W High is -3.8%, Dist 3Y High is -3.8%
3 Weak multi-year price returns
3Y Excs Rtn is -49%
4 Meaningful short interest
Short Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 12%
5 Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -92 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -15%
6 Expensive valuation multiples
P/CFOPrice/(Cash Flow from Operations). CFO is cash before capital expenditures. is 64x
7 Stock price has recently run up significantly
6M Rtn6 month market price return is 201%, 12M Rtn12 month market price return is 349%
8 Weak revenue growth
Rev Chg LTMRevenue Change % Last Twelve Months (LTM) is -4.3%, Rev Chg QQuarterly Revenue Change % is -13%
9 Significant share based compensation
SBC/Rev LTMShare Based Compensation / Revenue (Sales), Last Twelve Months (LTM) is 16%
10 Valuation getting more expensive
P/S 6M Chg %Price/Sales change over 6 months. Declining P/S indicates valuation has become less expensive. is 210%
11 Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -5.2%
12 Key risks
TXG key risks include [1] a sharp decline in instrument revenue due to tightening research budgets, Show more.

TXG in ETFs

Weight = TXG's share of each fund

VTI0.01%
ITOT0.01%
IWM0.23%
VB0.07%
ARKK3.0%
IBB0.49%
IWO0.46%
VTWO0.18%
+9 more covered ETFs

Valuation & Metrics

Price Chart

Why The Stock Moved

Qualitative Assessment

AI Analysis | Feedback

Updated on 9/3/2026

10x Genomics (TXG) stock has gained about 120% since 5/31/2026 because of the following key factors:

1. Exceptional customer reception and strong order flow for the new Atera platform.

10x Genomics experienced an "extraordinary customer response" to its newly launched Atera spatial biology platform, with booked orders exceeding the full-year shipment target of 40 units as of June 30, 2026. This generated "very strong early order flow" and significant investor enthusiasm, leading to a stock jump of 9.6% after the Q2 2026 earnings report. The Atera platform, introduced at the AACR Annual Meeting 2026, delivers whole-transcriptome spatial analysis with single-cell sensitivity at scale, addressing previous technological limitations.

2. Stronger-than-expected Q2 2026 financial results and raised full-year revenue guidance.

For the second fiscal quarter ended June 30, 2026, 10x Genomics reported an adjusted loss per share of -$0.14, which was significantly better than analysts' consensus estimates of -$0.24. Revenue reached $151.0 million, surpassing the consensus estimate of $146.67 million. While reported revenue declined 12.7% year-over-year due to non-recurring patent litigation settlements in the prior year, revenue, excluding these settlements, increased 3% over the corresponding period of 2025. The company also raised its full-year 2026 revenue guidance to a range of $610 million to $630 million, up from the previous range of $600 million to $625 million, indicating management's confidence. Additionally, gross margin improved to 74% in Q2 2026, up from 72% in the prior year period.

Show more
Updated on 9/3/2026

10x Genomics (TXG) stock has gained about 120% since 5/31/2026 because of the following key factors:

1. Exceptional customer reception and strong order flow for the new Atera platform.

10x Genomics experienced an "extraordinary customer response" to its newly launched Atera spatial biology platform, with booked orders exceeding the full-year shipment target of 40 units as of June 30, 2026. This generated "very strong early order flow" and significant investor enthusiasm, leading to a stock jump of 9.6% after the Q2 2026 earnings report. The Atera platform, introduced at the AACR Annual Meeting 2026, delivers whole-transcriptome spatial analysis with single-cell sensitivity at scale, addressing previous technological limitations.

2. Stronger-than-expected Q2 2026 financial results and raised full-year revenue guidance.

For the second fiscal quarter ended June 30, 2026, 10x Genomics reported an adjusted loss per share of -$0.14, which was significantly better than analysts' consensus estimates of -$0.24. Revenue reached $151.0 million, surpassing the consensus estimate of $146.67 million. While reported revenue declined 12.7% year-over-year due to non-recurring patent litigation settlements in the prior year, revenue, excluding these settlements, increased 3% over the corresponding period of 2025. The company also raised its full-year 2026 revenue guidance to a range of $610 million to $630 million, up from the previous range of $600 million to $625 million, indicating management's confidence. Additionally, gross margin improved to 74% in Q2 2026, up from 72% in the prior year period.

3. Positive analyst upgrades and increased price targets.

Following its Q2 2026 results and the strong performance of its Atera platform, 10x Genomics saw an improvement in analyst sentiment. On August 4, 2026, the company was upgraded to a Zacks Rank #2 (Buy), reflecting an upward trend in earnings estimates. Several investment firms, including Stifel, Citi, and Morgan Stanley, raised their price targets for TXG. Notably, Stifel doubled its price target from $25 to $50 while maintaining a "Buy" rating. The consensus price target among analysts increased from $41.54 to $49.54.

4. Strategic growth initiatives including an acquisition and key research collaborations.

10x Genomics expanded its multiomics strategy through the acquisition of Proteintech Genomics, a division of Proteintech Group, which added advanced protein detection capabilities to its existing platforms. Furthermore, the company announced multi-year research collaborations with prominent institutions like Cleveland Clinic and Lausanne University Hospital. These collaborations aim to advance research in diagnostic applications of single cell and spatial technologies for cancer care, aligning with the company's diagnostics strategy.

5. Favorable trends and increased investment within the broader biotechnology market.

The biotechnology market is experiencing significant expansion, with projections indicating an increase from USD 2.02 trillion in 2026 to approximately USD 6.34 trillion by 2035, representing a compound annual growth rate (CAGR) of 13.61%. This growth is driven by rising demand for personalized medicine, bio-agriculture, and increased investment by pharmaceutical and biotech industries, coupled with the integration of advanced technologies like AI-driven drug discovery and spatial multi-omics. Healthcare venture investment in the first half of 2026 reached approximately $31 billion, with Q2 2026 being the strongest quarter, demonstrating continued capital concentration in later-stage and clinically validated programs.

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Stock Movement Drivers

Fundamental Drivers

The 121.3% change in TXG stock from 5/31/2026 to 9/5/2026 was primarily driven by a 132.2% change in the company's P/S Multiple.
(LTM values as of)53120269052026Change
Stock Price ($)28.3062.65121.3%
Change Contribution By: 
Total Revenues ($ Mil)639617-3.4%
P/S Multiple5.713.2132.2%
Shares Outstanding (Mil)128130-1.3%
Cumulative Contribution121.3%

LTM = Last Twelve Months as of date shown

Market Drivers

5/31/2026 to 9/5/2026
ReturnCorrelation
TXG121.3% 
Market (SPY)1.8%43.1%
Sector (XLV)14.7%7.9%

Fundamental Drivers

The 171.8% change in TXG stock from 2/28/2026 to 9/5/2026 was primarily driven by a 189.6% change in the company's P/S Multiple.
(LTM values as of)22820269052026Change
Stock Price ($)23.0562.65171.8%
Change Contribution By: 
Total Revenues ($ Mil)643617-4.0%
P/S Multiple4.613.2189.6%
Shares Outstanding (Mil)127130-2.2%
Cumulative Contribution171.8%

LTM = Last Twelve Months as of date shown

Market Drivers

2/28/2026 to 9/5/2026
ReturnCorrelation
TXG171.8% 
Market (SPY)12.6%45.1%
Sector (XLV)7.5%23.3%

Fundamental Drivers

The 347.2% change in TXG stock from 8/31/2025 to 9/5/2026 was primarily driven by a 390.7% change in the company's P/S Multiple.
(LTM values as of)83120259052026Change
Stock Price ($)14.0162.65347.2%
Change Contribution By: 
Total Revenues ($ Mil)644617-4.3%
P/S Multiple2.713.2390.7%
Shares Outstanding (Mil)124130-4.8%
Cumulative Contribution347.2%

LTM = Last Twelve Months as of date shown

Market Drivers

8/31/2025 to 9/5/2026
ReturnCorrelation
TXG347.2% 
Market (SPY)20.4%39.7%
Sector (XLV)26.4%23.6%

Fundamental Drivers

The 20.8% change in TXG stock from 8/31/2023 to 9/5/2026 was primarily driven by a 24.0% change in the company's P/S Multiple.
(LTM values as of)83120239052026Change
Stock Price ($)51.8562.6520.8%
Change Contribution By: 
Total Revenues ($ Mil)5686178.5%
P/S Multiple10.613.224.0%
Shares Outstanding (Mil)117130-10.2%
Cumulative Contribution20.8%

LTM = Last Twelve Months as of date shown

Market Drivers

8/31/2023 to 9/5/2026
ReturnCorrelation
TXG20.8% 
Market (SPY)77.1%45.2%
Sector (XLV)34.7%35.1%

Return vs. Risk

Price Returns Compared

 202120222023202420252026Total [1]
Returns
TXG Return5%-76%54%-74%14%288%-55%
Peers Return-4%-43%10%-21%-9%9%-54%
S&P 500 Return27%-19%24%23%16%13%106%

Monthly Win Rates [3]
TXG Win Rate50%17%67%25%58%89% 
Peers Win Rate50%37%48%40%47%58% 
S&P 500 Win Rate75%42%67%75%67%56% 

Max Drawdowns [4]
TXG Max Drawdown-34%-84%-46%-76%-56%-28% 
Peers Max Drawdown-35%-58%-46%-41%-48%-39% 
S&P 500 Max Drawdown-5%-25%-10%-8%-19%-9% 


[1] Cumulative total returns since the beginning of 2021
[2] Peers: ILMN, BDX, BIO, LAB, PACB.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 9/4/2026 (YTD)

How Low Can It Go

EventTXGS&P 500
2025 US Tariff Shock
  % Loss-41.0%-18.8%
  % Gain to Breakeven69.5%23.1%
  Time to Breakeven85 days79 days
Summer-Fall 2023 Five Percent Yield Shock
  % Loss-43.6%-9.5%
  % Gain to Breakeven77.3%10.5%
  Time to Breakeven1022 days24 days
2020 COVID-19 Crash
  % Loss-43.1%-33.7%
  % Gain to Breakeven75.7%50.9%
  Time to Breakeven107 days140 days

Compare to ILMN, BDX, BIO, LAB, PACB

In The Past

10x Genomics's stock fell -41.0% during the 2025 US Tariff Shock. Such a loss loss requires a 69.5% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

EventTXGS&P 500
2025 US Tariff Shock
  % Loss-41.0%-18.8%
  % Gain to Breakeven69.5%23.1%
  Time to Breakeven85 days79 days
Summer-Fall 2023 Five Percent Yield Shock
  % Loss-43.6%-9.5%
  % Gain to Breakeven77.3%10.5%
  Time to Breakeven1022 days24 days
2020 COVID-19 Crash
  % Loss-43.1%-33.7%
  % Gain to Breakeven75.7%50.9%
  Time to Breakeven107 days140 days

Compare to ILMN, BDX, BIO, LAB, PACB

In The Past

10x Genomics's stock fell -41.0% during the 2025 US Tariff Shock. Such a loss loss requires a 69.5% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

About 10x Genomics (TXG)

10x Genomics (TXG) is a leading life science technology company focused on developing and selling advanced instruments, consumables, and software to analyze biological systems. The company empowers researchers to explore biology at a highly detailed level, specifically by enabling single-cell analysis and understanding gene expression patterns within the spatial context of tissues. Their technologies provide critical insights that accelerate discovery across various fields.

The core of 10x Genomics' product portfolio includes their Chromium and Chromium Connect instruments, which underpin a suite of sophisticated single-cell solutions. These solutions allow scientists to measure gene activity on a cell-by-cell basis (Single Cell Gene Expression), profile the activity of immune cells (Single Cell Immune Profiling), and analyze epigenetics or DNA organization (Single Cell ATAC). A notable innovation is the Single Cell Multiome ATAC + Gene Expression solution, which simultaneously measures genetic activity and epigenetic programming within tens of thousands of individual cells. Additionally, the company offers the Visium Spatial Gene Expression solution, providing crucial information on how genes are expressed in specific locations across a tissue sample, and can be combined with immunofluorescence for protein co-detection.

10x Genomics serves a diverse global customer base, including academic institutions, government research bodies, biopharmaceutical companies, and biotechnology firms. These customers, spread across North America, Europe, the Middle East, Africa, China, and the Asia Pacific, leverage 10x Genomics' cutting-edge platforms to advance basic research, therapeutic development, and our fundamental understanding of health and disease.

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1. Illumina for single-cell and spatial genomics.

2. The Intel for advanced biological discovery.

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  • Chromium Instruments & Consumables: These are the core instruments (Chromium and Chromium Connect) and associated microfluidic chips, slides, and reagents that enable their advanced biological analyses.
  • Single Cell Gene Expression: A solution used to measure the activity of genes on a cell-by-cell basis.
  • Single Cell Immune Profiling: A solution for quantifying the activity of individual immune cells and their specific targets.
  • Single Cell Assay for Transposase Accessible Chromatin (ATAC): A solution that measures epigenetics, specifically the physical organization of DNA, at a single-cell resolution.
  • Single Cell Multiome ATAC + Gene Expression: A comprehensive solution for simultaneously measuring both genetic activity and epigenetic programming within the same individual cells.
  • Visium Spatial Gene Expression Solution: A solution designed to measure and map gene expression patterns across a single tissue sample, capable of combining with immunofluorescence for protein co-detection.

AI Analysis | Feedback

10x Genomics (TXG) primarily sells its life science technology products to various institutions rather than directly to individuals. Based on the provided company description, its major customers can be broadly categorized into the following types of institutions:

  • Academic Institutions: This includes universities, research hospitals, and other educational and research centers.
  • Government Institutions: This encompasses national research laboratories and government-funded research organizations.
  • Biopharmaceutical and Biotechnology Companies: This category includes private sector firms involved in drug discovery, development, diagnostics, and other advanced biological research.

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Serge Saxonov, Chief Executive Officer, Co-founder, and Director

  • Serge Saxonov co-founded 10x Genomics in 2012 and has served as CEO since its inception, guiding the company through rapid growth and its public debut on Nasdaq (TXG).
  • Before 10x Genomics, he was a founding architect and director of Research and Development at 23andMe, where he developed the company's core technology and product concepts.
  • He also served as Vice President of Applications at QuantaLife, a privately-held life sciences company that was acquired by Bio-Rad Laboratories in 2011.
  • He earned an A.B. in Applied Mathematics from Harvard College and a Ph.D. in Biomedical Informatics from Stanford University.

Adam Taich, Chief Financial Officer

  • Adam Taich was appointed Chief Financial Officer of 10x Genomics, effective August 12, 2024.
  • Prior to joining 10x Genomics, he served as Chief Strategy Officer at Standard BioTools Inc.
  • He previously held the roles of interim Chief Executive Officer, Chief Business Officer, and Executive Vice President of Life Sciences at SomaLogic, Inc., a proteomics company.
  • He also had a nearly 20-year career at Thermo Fisher Scientific, where he held various senior leadership positions across finance, strategy, and general management.

Ben Hindson, Co-founder, President, Chief Scientific Officer, and Director

  • Ben Hindson co-founded 10x Genomics in 2012 and has served as Chief Scientific Officer and a Director since its founding.
  • Before co-founding 10x Genomics, he was the Co-founder and Chief Scientific Officer of Quantalife, a privately-held life sciences company focused on a droplet digital PCR platform.
  • Quantalife was sold to Bio-Rad Laboratories in 2011.
  • Earlier in his career, he held various positions at Lawrence Livermore National Laboratory in the Chemical and Biological Weapons Nonproliferation Program.
  • He holds a B.S. and Ph.D. in Chemistry from Deakin University, Australia.

Mennah Moustafa, Chief Commercial Officer

  • Mennah Moustafa was named Chief Commercial Officer of 10x Genomics, effective August 1, 2024.
  • She joined 10x Genomics in April 2022 as Senior Vice President of Commercial Operations and served as the interim Chief Commercial Officer since January 2024.
  • Moustafa brings over two decades of experience in commercial and business development within the biotechnology and life sciences industries.
  • Prior to 10x Genomics, she was Abcam's Head of Commercial for the Americas, and later led Business Development and the Customer Experience Journey.
  • She also spent a decade at Sigma-Aldrich.

AI Analysis | Feedback

The key risks to 10x Genomics' business include:

  1. Macroeconomic Headwinds and Research Funding Uncertainty

    A significant risk for 10x Genomics is the tightening of research budgets and macroeconomic uncertainty, particularly affecting academic and government funding in the United States. This environment leads to a slowdown in instrument sales and cautious customer spending, impacting a substantial portion of the company's revenue (approximately 40-50% is linked to U.S. academic and government funding). Delays, reductions, or cancellations of grants, along with potential future budget cuts, create unpredictable purchasing behavior and reduced visibility for the company. In 2025, 10x Genomics experienced a sharp 37% year-over-year decrease in instrument revenue in Q3 due to this uncertainty.

  2. Intense Competition and Pricing Pressure

    The life science technology sector is highly competitive, with numerous established companies and emerging firms vying for market share in single-cell and spatial biology. This competitive landscape results in pricing pressure, as 10x Genomics proactively lowers prices on some assays (e.g., a 20-30% drop for Chromium Flex) to drive volume, which can immediately pressure top-line revenue and gross margins. To maintain its competitive edge and avoid technological obsolescence, the company must continuously invest heavily in research and development.

  3. Reliance on Chromium Solutions and Fluctuating Instrument Sales

    10x Genomics operates on a "razor-and-blade" business model, where initial instrument sales are critical for generating a long-term stream of consumables revenue. The company's heavy reliance on its Chromium solutions makes it vulnerable if market demand shifts or if competitors introduce superior technologies. Fluctuations in instrument sales directly impact overall revenue, and a significant slowdown in these sales, as observed with a 37% year-over-year drop in Q3 2025 instrument revenue, poses a challenge to its core business model. The unpredictability in operating results, partly due to these sales fluctuations, complicates future assessments and strategic planning.

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  • Emergence of alternative single-cell analysis platforms that offer significantly higher throughput, lower cost per cell, or simpler workflows, potentially challenging the market dominance of 10x Genomics' microfluidics-based Chromium instruments.
  • Rapid advancements and commercialization of competing spatial genomics technologies that provide superior resolution (e.g., sub-cellular), increased multiplexing capabilities, or more comprehensive multi-omic integration in tissue, thereby threatening the market position of 10x Genomics' Visium platform.

AI Analysis | Feedback

10x Genomics (NASDAQ: TXG) addresses significant and growing markets with its single-cell and spatial biology solutions.

  • As of early 2025, 10x Genomics estimated its serviceable addressable market (SAM) for single-cell and spatial solutions combined to be approximately $13 billion globally.
  • In a 2021 statement, 10x Genomics' CEO indicated that the broader life science research tools market, which the company aims to address, was about $60 billion globally and growing rapidly.

Single-Cell Analysis Market:

  • The global single-cell analysis market was valued at approximately $4.29 billion in 2024 and is projected to reach $19.90 billion by 2035. North America holds the largest share of this market.
  • Another estimate places the global single-cell analysis market at $4.32 billion in 2025, expected to grow to $12.58 billion by 2034. North America's share of this market was $1.90 billion in 2025.
  • The single-cell analysis market was valued at $1.2 billion in 2022 and is projected to reach $1.7 billion by 2025.

Spatial Genomics and Transcriptomics Market (Spatial Biology):

  • The global spatial genomics and transcriptomics market was valued at approximately $420 million in 2024 and is projected to reach $1.15 billion by 2030.
  • The global spatial transcriptomics market size was estimated at $385.7 million in 2024 and is projected to reach $1,306.4 million by 2033. North America held the largest share of 58.09% of this global market in 2024.
  • Another report states the global spatial transcriptomics market size at $469.36 million in 2025, predicted to increase to approximately $1,569.03 million by 2034. In 2024, North America dominated this market with a 48% share.

AI Analysis | Feedback

10x Genomics (TXG) is expected to drive future revenue growth over the next 2-3 years through several key strategies:

  1. New Product Launches and Innovation: The company consistently introduces new instruments and assays, such as Chromium GEM-X, Visium HD, Xenium Prime 5K assay, and Flex APEX. These innovations aim to enhance sensitivity, throughput, and cost-effectiveness of biological analysis, while also enabling multiomic spatial insights, thereby expanding product utility and market penetration.
  2. Growth in Consumables Revenue: Despite facing challenges in instrument sales due to capital expenditure constraints, the utilization of 10x Genomics' installed base of instruments is expected to drive significant growth in consumables revenue for both single-cell and spatial solutions. The adoption of new assays, like Flex APEX, is specifically boosting reaction volumes and contributing to higher consumables pull-through.
  3. Expansion in the Spatial Biology Market: The spatial transcriptomics and genomics market is experiencing substantial growth, and 10x Genomics, with its Visium HD and Xenium platforms, is a key player in this expanding field. The company is strategically targeting applications in oncology, immunology, and neuroscience, and broadening the use of its spatial solutions from fundamental research to translational and clinical applications.
  4. Increased Focus on the Biopharmaceutical Sector: 10x Genomics aims to significantly increase the revenue contribution from biopharmaceutical customers, with a strategic goal to raise this segment's share from its current 15%-20% to approximately 50%. This focus on the biopharma sector is anticipated to provide a more stable and potentially higher-spending customer base.
  5. International Market Expansion: To counter regional market headwinds, particularly in the US, 10x Genomics is prioritizing accelerated growth in the EMEA (Europe, Middle East, and Africa) and APAC (Asia Pacific) markets. This involves strategic shipments and installations to expand the company's global installed base in these regions.

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Share Repurchases

  • 10x Genomics had a 5-Year Share Buyback Ratio of -3.20% as of December 2025, indicating potential share issuance rather than buybacks.

Share Issuance

  • In February 2026, 10x Genomics filed a shelf registration for US$138.83 million, covering 7,661,479 Class A shares related to an employee stock plan.
  • Insider sales by executives in August and November 2025, including the CFO and President/Chief Scientific Officer, were primarily for tax withholding obligations from vested restricted stock units.

Inbound Investments

  • Institutional investors held approximately 84.68% of 10x Genomics' stock as of March 7, 2026.
  • Major institutional shareholders include Vanguard Group Inc, ARK Investment Management LLC, Fmr Llc, and BlackRock, Inc.
  • JPMorgan Chase & Co. significantly increased its stake in 10x Genomics in Q3 (likely 2025), acquiring an additional 951,495 shares for a total of 1,073,865 shares valued at approximately $12.6 million.

Outbound Investments

  • In August 2025, 10x Genomics signed a definitive agreement to acquire Scale Biosciences, Inc., a single cell genomics technology company.
  • The upfront payment for the Scale Biosciences acquisition in August 2025 included $9.2 million in cash and $13.5 million (1,099,992 shares) in Class A common stock.
  • An additional $20.0 million payment, in cash and Class A common stock, is expected in Q1 2026 for a technology transfer completed in Q3 2025 related to the Scale Biosciences acquisition.

Capital Expenditures

  • 10x Genomics invested $1.8 million in capital expenditures during Q4 2025, representing a 158.7% increase from the previous quarter.
  • The company anticipates 0%-4% revenue growth for 2026 amidst a challenging capital expenditure environment, with ongoing pressure on instrument sales due to funding constraints.

Better Bets vs. 10x Genomics (TXG)

Peer Outperformance in Life Sciences Tools & Services

TXG has outperformed 54% of its 108 Life Sciences Tools & Services peers over 5Y. Among the peers that beat it are IQV and A. Life Sciences Tools & Services ranks 8th of 10 industries in Health Care by median 5Y return. The sector’s gains have largely come from elsewhere.
Share of Life Sciences Tools & Services constituents that TXG has outperformed, by holding period. Peers without a full price history over a given window are excluded from that window.
1Y
98%
of 127 industry peers · 348.8% return
3Y
68%
of 117 industry peers · 20.1% return
5Y
54%
of 108 industry peers · -66.2% return
Life Sciences Tools & Services peers with revenue growth within 4pp of TXG's that beat it on at least 2 of 3 windows, and by at least 20pp over 5Y. Growth is matched by construction, so the gap is largely a re-rating gap. The multiple column is the context for it.
Ticker Name Rev Growth 3Y Avg P/E 1Y3Y5Y 5Y Gap
TXG 10x Genomics 3.0% -108.4x 348.8%20.1%-66.2%
IQV IQVIA 5.0% 32.3x 42.7%22.4%1.7% +68pp
A Agilent Technologies 2.0% 29.5x 18.1%30.9%-12.8% +53pp
Price returns, excluding dividends. P/E shown for context only and not used for matching.
Median price return by industry across the Health Care sector, ranked by 5Y. Life Sciences Tools & Services is TXG's own industry. Use this to see which corners of the sector have carried the returns.
Industry Names 1Y med3Y med5Y med Top 3 by 5Y
Health Care Distributors 7 14.0%94.3%127.8% CAH 414% · MCK 351% · COR 179%
Managed Health Care 8 32.5%0.9%3.3% OSCR 77% · HQY 48% · ELV 16%
Health Care Services 20 19.7%53.1%-1.5% HIMS 238% · RDNT 134% · DGX 68%
Health Care Facilities 24 -1.0%7.5%-19.0% THC 249% · NHC 244% · ENSG 108%
Health Care Equipment 50 -4.5%-4.9%-24.0% POCI 10775% · UFPT 318% · GKOS 200%
Health Care Supplies 12 27.9%-14.2%-35.5% LNTH 272% · HAE 59% · MMSI 23%
Pharmaceuticals 63 -1.5%1.9%-36.4% LQDA 2406% · INDV 1148% · ETON 1022%
Life Sciences Tools & Services ← 109 1.6%-27.8%-73.9% SNWV 1688% · MEDP 203% · AXGN 178%
Biotechnology 363 5.6%-26.4%-76.8% BRTX 73900% · DNTH 1558% · CELZ 1486%
Health Care Technology 20 -24.5%-57.0%-78.6% SPOK 68% · HSTM -2% · VEEV -13%
Median of constituents with a full price history over each window. Top names are unfiltered by size in this render.

Latest Trefis Analyses

Recent Active Movers

Peer Comparisons

Peers to compare with:

Financials

TXGILMNBDXBIOLABPACBMedian
Name10x Geno.Illumina Becton D.Bio-Rad .Standard.Pacific . 
Mkt Price62.65218.22184.74386.110.691.35123.70
Mkt Cap8.133.050.810.30.30.49.2
Rev LTM6174,49323,2502,589851591,603
Op Inc LTM-928923,344224-63-17981
FCF LTM1219312,509353-83-131237
FCF 3Y Avg487732,768293-106-183170
CFO LTM1271,0953,262493-80-118310
CFO 3Y Avg629233,487458-100-173260

Growth & Margins

TXGILMNBDXBIOLABPACBMedian
Name10x Geno.Illumina Becton D.Bio-Rad .Standard.Pacific . 
Rev Chg LTM-4.3%4.9%17.4%1.4%-4.8%2.0%1.7%
Rev Chg 3Y Avg3.0%0.3%7.1%-2.1%-5.5%4.6%1.6%
Rev Chg Q-12.6%9.4%5.4%-0.1%-7.6%-1.9%-1.0%
QoQ Delta Rev Chg LTM-3.4%2.3%1.1%-0.0%-1.9%-0.5%-0.2%
Op Inc Chg LTM39.0%8.3%26.1%0.4%30.6%70.4%28.3%
Op Inc Chg 3Y Avg17.7%675.4%10.7%-13.1%1.9%-7.6%6.3%
Op Mgn LTM-14.9%19.9%14.4%8.7%-74.0%-112.3%-3.1%
Op Mgn 3Y Avg-22.9%13.4%13.5%10.1%-84.0%-223.6%-6.4%
QoQ Delta Op Mgn LTM-2.4%0.3%-0.5%-0.2%17.0%-0.4%-0.3%
CFO/Rev LTM20.6%24.4%14.0%19.0%-94.9%-74.1%16.5%
CFO/Rev 3Y Avg9.9%21.0%16.8%17.8%-101.3%-101.2%13.4%
FCF/Rev LTM19.7%20.7%10.8%13.6%-97.6%-82.0%12.2%
FCF/Rev 3Y Avg7.7%17.6%13.3%11.4%-107.9%-107.1%9.6%

Valuation

TXGILMNBDXBIOLABPACBMedian
Name10x Geno.Illumina Becton D.Bio-Rad .Standard.Pacific . 
Mkt Cap8.133.050.810.30.30.49.2
P/S13.27.32.24.03.22.63.6
P/Op Inc-88.736.915.246.0-4.3-2.36.4
P/EBIT-493.729.619.925.9-3.7-3.48.3
P/E-108.439.953.946.43.2-3.221.6
P/CFO64.130.115.621.0-3.4-3.618.3
Total Yield-0.9%2.5%4.2%2.2%31.5%-31.3%2.3%
Dividend Yield0.0%0.0%2.3%0.0%0.0%0.0%0.0%
FCF Yield 3Y Avg1.7%4.2%5.3%4.0%-22.9%-45.8%2.8%
D/E0.00.10.30.10.11.70.1
Net D/E-0.10.00.3-0.0-1.71.10.0

Returns

TXGILMNBDXBIOLABPACBMedian
Name10x Geno.Illumina Becton D.Bio-Rad .Standard.Pacific . 
1M Rtn37.4%12.6%4.3%12.8%-14.3%15.9%12.7%
3M Rtn101.8%34.4%23.1%31.2%-40.4%-6.9%27.1%
6M Rtn201.1%75.1%12.0%43.1%-30.8%-2.2%27.6%
12M Rtn348.8%120.6%25.2%30.7%-47.3%6.3%27.9%
3Y Rtn20.1%40.3%-6.5%4.4%-76.5%-87.8%-1.1%
1M Excs Rtn37.3%12.5%4.2%12.6%-14.4%15.8%12.6%
3M Excs Rtn97.3%29.9%18.5%26.7%-44.9%-11.4%22.6%
6M Excs Rtn186.5%60.6%-2.5%28.6%-45.3%-16.7%13.0%
12M Excs Rtn343.0%104.7%7.2%14.7%-65.6%-9.8%10.9%
3Y Excs Rtn-49.4%-35.7%-82.0%-73.7%-147.8%-158.9%-77.8%

Comparison Analyses

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Financials

Segment Financials

Revenue by Segment
$ Mil20252024202320222021
Single Segment643611619516 
Consumables    419
Instruments    64
Services    7
Total643611619516490


Price Behavior

Price Behavior
Market Price$62.65 
Market Cap ($ Bil)8.1 
First Trading Date09/12/2019 
Distance from 52W High-3.8% 
   50 Days200 Days
DMA Price$49.88$28.69
DMA Trendupup
Distance from DMA25.6%118.4%
 3M1YR
Volatility78.0%72.5%
Downside Capture93.34171.57
Upside Capture400.44312.13
Correlation (SPY)44.1%40.0%
TXG Betas & Captures as of 8/31/2026

 1M2M3M6M1Y3Y
Beta1.552.652.492.372.242.01
Up Beta-1.321.781.791.862.642.12
Down Beta2.690.822.612.501.421.68
Up Capture503%628%658%623%945%1277%
Bmk +ve Days10213268138427
Stock +ve Days11183267125355
Down Capture20%147%75%144%138%112%
Bmk -ve Days11213259113324
Stock -ve Days10243259123386

[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with TXG
TXG364.5%72.3%2.41-
Sector ETF (XLV)26.5%16.0%1.2823.6%
Equity (SPY)19.7%12.8%1.1339.7%
Gold (GLD)24.6%29.2%0.7531.9%
Commodities (DBC)43.8%20.3%1.67-6.5%
Real Estate (VNQ)9.1%13.6%0.3915.3%
Bitcoin (BTCUSD)-28.1%43.8%-0.6322.4%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 5-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with TXG
TXG-16.1%69.9%0.04-
Sector ETF (XLV)6.6%15.1%0.2537.6%
Equity (SPY)12.8%17.2%0.5750.9%
Gold (GLD)19.1%18.8%0.8216.9%
Commodities (DBC)10.7%19.5%0.433.5%
Real Estate (VNQ)1.7%18.9%-0.0142.1%
Bitcoin (BTCUSD)10.2%52.6%0.3826.6%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 10-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with TXG
TXG2.6%67.2%0.35-
Sector ETF (XLV)10.8%16.7%0.5334.0%
Equity (SPY)15.3%17.9%0.7242.9%
Gold (GLD)12.4%16.3%0.6214.8%
Commodities (DBC)7.9%18.1%0.355.4%
Real Estate (VNQ)4.8%20.7%0.1933.5%
Bitcoin (BTCUSD)63.7%66.2%1.0321.1%

Smart multi-asset allocation framework can stack odds in your favor. Learn How

Short Interest

Short Interest: As Of Date8142026
Short Interest: Shares Quantity15.9 Mil
Short Interest: % Change Since 73120261.9%
Average Daily Volume3.5 Mil
Days-to-Cover Short Interest4.6 days
Basic Shares Quantity130.0 Mil
Short % of Basic Shares12.3%

Earnings Returns History

Updated 9/6/2026
Expand for More
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
8/6/202614.1%27.5%37.4%
5/7/2026-3.7%-4.0%30.2%
2/12/20263.5%7.8%-4.7%
11/6/202517.3%25.8%37.2%
8/7/2025-4.0%3.4%8.8%
5/8/20251.6%6.6%16.9%
2/12/2025-0.5%-3.7%-13.8%
10/29/20244.4%9.8%-2.0%
...
SUMMARY STATS   
# Positive141311
# Negative101113
Median Positive5.2%7.8%16.9%
Median Negative-4.1%-10.7%-13.8%
Max Positive18.5%27.5%44.8%
Max Negative-21.0%-26.6%-26.5%
Collapse to Preview
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
8/6/202614.1%27.5%37.4%
5/7/2026-3.7%-4.0%30.2%
2/12/20263.5%7.8%-4.7%
11/6/202517.3%25.8%37.2%
8/7/2025-4.0%3.4%8.8%
5/8/20251.6%6.6%16.9%
2/12/2025-0.5%-3.7%-13.8%
10/29/20244.4%9.8%-2.0%
8/8/20244.5%15.8%11.6%
4/30/2024-8.1%-10.7%-23.5%
2/15/20240.8%-6.4%-24.9%
11/2/20238.7%-0.1%26.7%
8/3/2023-4.2%-11.2%-7.6%
5/3/20231.3%0.7%1.1%
2/15/202311.2%3.8%4.0%
11/2/202218.5%13.0%44.8%
8/8/20223.3%9.4%-25.5%
5/4/2022-4.0%-24.5%-13.8%
2/16/2022-14.7%-18.7%-26.5%
11/3/202111.2%1.7%-16.0%
8/4/2021-5.2%-12.7%-0.7%
5/5/2021-21.0%-26.6%-1.5%
2/17/2021-0.6%-4.3%-10.2%
11/10/20205.9%5.2%15.9%
SUMMARY STATS   
# Positive141311
# Negative101113
Median Positive5.2%7.8%16.9%
Median Negative-4.1%-10.7%-13.8%
Max Positive18.5%27.5%44.8%
Max Negative-21.0%-26.6%-26.5%

SEC Filings

Expand for More
Report DateFiling DateFiling
06/30/202608/07/202610-Q
03/31/202605/08/202610-Q
12/31/202502/13/202610-K
09/30/202511/07/202510-Q
06/30/202508/08/202510-Q
03/31/202505/09/202510-Q
12/31/202402/13/202510-K
09/30/202410/29/202410-Q
06/30/202408/08/202410-Q
03/31/202404/30/202410-Q
12/31/202302/15/202410-K
09/30/202311/03/202310-Q
06/30/202308/04/202310-Q
03/31/202305/04/202310-Q
12/31/202202/16/202310-K
09/30/202211/03/202210-Q
Collapse to Preview
Report DateFiling DateFiling
06/30/202608/07/202610-Q
03/31/202605/08/202610-Q
12/31/202502/13/202610-K
09/30/202511/07/202510-Q
06/30/202508/08/202510-Q
03/31/202505/09/202510-Q
12/31/202402/13/202510-K
09/30/202410/29/202410-Q
06/30/202408/08/202410-Q
03/31/202404/30/202410-Q
12/31/202302/15/202410-K
09/30/202311/03/202310-Q
06/30/202308/04/202310-Q
03/31/202305/04/202310-Q
12/31/202202/16/202310-K
09/30/202211/03/202210-Q
06/30/202208/09/202210-Q
03/31/202205/05/202210-Q
12/31/202102/18/202210-K
09/30/202111/05/202110-Q
06/30/202108/06/202110-Q
03/31/202105/07/202110-Q
12/31/202002/26/202110-K
09/30/202011/12/202010-Q
06/30/202008/12/202010-Q
03/31/202005/12/202010-Q
12/31/201902/27/202010-K
09/30/201911/12/201910-Q

Recent Forward Guidance

Updated 8/7/2026

Latest: Q2 2026 Earnings Reported 8/6/2026

Forward GuidanceGuidance Change
MetricSourceLowMidHigh% Chg% DeltaChangePrior
2026 RevenueReported610.00 Mil620.00 Mil630.00 Mil1.2% RaisedGuidance: 612.50 Mil for 2026
2026 Revenue GrowthReported2.0%3.5%5.0% 1.5%RaisedGuidance: 2.0% for 2026


Prior: Q1 2026 Earnings Reported 5/7/2026

Forward GuidanceGuidance Change
MetricSourceLowMidHigh% Chg% DeltaChangePrior
2026 RevenueReported600.00 Mil612.50 Mil625.00 Mil0 AffirmedGuidance: 612.50 Mil for 2026
2026 Revenue GrowthReported0.0%2.0%4.0% 0AffirmedGuidance: 2.0% for 2026

Q4 2025 Earnings Reported 2/12/2026

Forward GuidanceGuidance Change
MetricSourceLowMidHigh% Chg% DeltaChangePrior
2026 RevenueReported600.00 Mil612.50 Mil625.00 Mil   
2026 Revenue GrowthReported0.0%2.0%4.0%   

Q3 2025 Earnings Reported 11/6/2025

Forward GuidanceGuidance Change
MetricSourceLowMidHigh% Chg% DeltaChangePrior
Q4 2025 RevenueReported154.00 Mil156.00 Mil158.00 Mil9.9% Higher NewGuidance: 142.00 Mil for Q3 2025

Insider Activity

Updated 9/3/2026
Expand for More
#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Saxonov, SergeChief Executive OfficerDirectSell828202663.6910,486667,90168,493,842Form
2Saxonov, SergeChief Executive OfficerDirectSell826202663.0218,5451,168,77568,433,339Form
3Taich, AdamChief Financial OfficerDirectSell826202663.0217,1661,081,85322,860,459Form
4Hindson, Benjamin JSee RemarksDirectSell826202663.0213,818870,86030,766,987Form
5Suliman, Shehnaaz DirectSell826202663.652,207140,4781,878,662Form
Collapse to Preview
#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Saxonov, SergeChief Executive OfficerDirectSell828202663.6910,486667,90168,493,842Form
2Saxonov, SergeChief Executive OfficerDirectSell826202663.0218,5451,168,77568,433,339Form
3Taich, AdamChief Financial OfficerDirectSell826202663.0217,1661,081,85322,860,459Form
4Hindson, Benjamin JSee RemarksDirectSell826202663.0213,818870,86030,766,987Form
5Suliman, Shehnaaz DirectSell826202663.652,207140,4781,878,662Form
6Teichmann, Sarah A DirectSell817202657.152,273129,9021,603,515Form
7Teichmann, Sarah A DirectSell817202657.295,278302,3771,737,663Form
8Stuelpnagel, John R DirectSell813202657.7520,0001,155,05520,123,144Form
9Saxonov, SergeChief Executive OfficerDirectSell624202634.4430,0001,033,26938,175,143Form
10Suliman, Shehnaaz DirectSell618202632.635,723186,7561,035,170Form
11Saxonov, SergeChief Executive OfficerDirectSell527202624.7110,718264,83328,128,459Form
12Saxonov, SergeChief Executive OfficerDirectSell527202624.4418,175444,22428,085,679Form
13Hindson, Benjamin JSee RemarksDirectSell527202624.4411,595283,39912,269,633Form
14Taich, AdamChief Financial OfficerDirectSell527202624.4415,098369,0189,285,277Form
15Saxonov, SergeChief Executive OfficerDirectSell416202624.565,000122,78428,664,490Form
16Saxonov, SergeChief Executive OfficerDirectSell325202619.525,00097,61222,885,465Form
17Saxonov, SergeChief Executive OfficerDirectSell325202619.1310,000191,29722,520,879Form
18Saxonov, SergeChief Executive OfficerDirectSell304202622.7316,152367,09727,356,493Form
19Teichmann, Sarah A DirectSell227202619.417,579147,108519,800Form
20Saxonov, SergeChief Executive OfficerDirectSell225202618.589,632178,92819,726,725Form
21Taich, AdamChief Financial OfficerDirectSell225202618.588,968166,5935,357,750Form
22Hindson, Benjamin JSee RemarksDirectSell225202618.587,826145,3797,890,865Form
23Taich, AdamChief Financial OfficerDirectSell1125202519.0011,888225,8525,649,809Form
24Hindson, Benjamin JSee RemarksDirectSell1125202519.008,283157,3638,218,760Form
25Saxonov, SergeChief Executive OfficerDirectSell1125202519.0013,261251,93619,407,827Form

Investor Activity (13F)

Updated Sep 6, 2026
13F holdings as of Mar 31, 2026 (Q1 2026)

Active managers (13F portfolio over $250M, at least 3 holdings) with a position over $5M that is either over 10% of their portfolio or held in a concentrated book of 50 or fewer total positions. Index/ETF, sovereign, bank, community-bank and charitable/donor-advised filers are excluded.

Active ManagerValue% of PortfolioTotal PositionsQoQFiling
Casdin Capital, LLC$48.3 Mil3.7%40ADD +62.5%13F
Sands Capital Alternatives, LLC$10.2 Mil2.4%21Hold13F
Active ManagerValue% of PortfolioTotal PositionsQoQFiling
Casdin Capital, LLC$48.3 Mil3.7%40ADD +62.5%13F
Active Manager
Active ManagerValue% of PortfolioTotal PositionsQoQFiling
Casdin Capital, LLC$48.3 Mil3.7%40ADD +62.5%13F
Sands Capital Alternatives, LLC$10.2 Mil2.4%21Hold13F
Core Cache Last Updated: 9/5/2026