Penumbra (PEN)


Market Price (11/5/2026): $322.49 | Market Cap: $12.7 BilSector: Health Care | Industry: Health Care Equipment

Penumbra (PEN)


Market Price (11/5/2026): $322.49
Market Cap: $12.7 Bil
Sector: Health Care
Industry: Health Care Equipment

Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.

0

Attractive cash flow generation
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 17%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 13%

Low stock price volatility
Vol 12M is 27%

Megatrend and thematic drivers
Megatrends include Precision Medicine, and Aging Population & Chronic Disease. Themes include Targeted Therapies, and Geriatric Care.

Weak multi-year price returns
3Y Excs Rtn is -13%

Expensive valuation multiples
P/EBITPrice/EBIT or Price/(Operating Income) ratio is 61x, P/CFOPrice/(Cash Flow from Operations). CFO is cash before capital expenditures. is 49x, P/EPrice/Earnings or Price/(Net Income) is 81x

Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -4.2%

Key risks
PEN key risks include [1] significant litigation and regulatory fallout from the Class I recall of its Jet 7 catheter linked to patient deaths, Show more.

0 Attractive cash flow generation
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 17%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 13%
1 Low stock price volatility
Vol 12M is 27%
2 Megatrend and thematic drivers
Megatrends include Precision Medicine, and Aging Population & Chronic Disease. Themes include Targeted Therapies, and Geriatric Care.
3 Weak multi-year price returns
3Y Excs Rtn is -13%
4 Expensive valuation multiples
P/EBITPrice/EBIT or Price/(Operating Income) ratio is 61x, P/CFOPrice/(Cash Flow from Operations). CFO is cash before capital expenditures. is 49x, P/EPrice/Earnings or Price/(Net Income) is 81x
5 Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -4.2%
6 Key risks
PEN key risks include [1] significant litigation and regulatory fallout from the Class I recall of its Jet 7 catheter linked to patient deaths, Show more.

PEN in ETFs

Weight = PEN's share of each fund

VTI0.02%
ITOT0.02%
IWB0.02%
IJH0.37%
VB0.15%
IJK0.73%
MDYG0.72%
NUSC0.70%
+20 more covered ETFs

Valuation & Metrics

Price Chart

Why The Stock Moved

Qualitative Assessment

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Updated on 11/1/2026

Penumbra (PEN) stock has remained largely at the same level since 7/31/2026 because of the following key factors:

1. Pending Acquisition by Boston Scientific Limited Upside and Downside.

Penumbra's stock movement since July 31, 2026, was significantly influenced by the pending acquisition by Boston Scientific, announced on January 14, 2026, for $374 per share in cash or stock, with an expected close in early 2027. This agreed-upon acquisition price likely established an effective ceiling for Penumbra's stock, as the market discounted the price to reflect the time value of money and the remaining regulatory risks associated with the deal. This created a relatively stable trading range below the acquisition price, limiting significant upward or downward swings.

2. Mixed Fiscal Q3 2026 Financial Results.

Penumbra reported its fiscal Q3 2026 earnings (for the period ending September 30, 2026) on October 29, 2026, which presented a mixed financial picture. The company announced robust revenue growth of 15.6% year-over-year, reaching $410.1 million, surpassing analyst estimates of $401.41 million. This positive revenue performance was, however, partially offset by a diluted earnings per share (EPS) of $1.07, which missed the consensus estimate of $1.20, and a decrease in net income to $42.3 million from $45.9 million in fiscal Q3 2025. This combination of strong top-line growth and a bottom-line miss contributed to a balanced market reaction, preventing significant directional movement in the stock.

Show more
Updated on 11/1/2026

Penumbra (PEN) stock has remained largely at the same level since 7/31/2026 because of the following key factors:

1. Pending Acquisition by Boston Scientific Limited Upside and Downside.

Penumbra's stock movement since July 31, 2026, was significantly influenced by the pending acquisition by Boston Scientific, announced on January 14, 2026, for $374 per share in cash or stock, with an expected close in early 2027. This agreed-upon acquisition price likely established an effective ceiling for Penumbra's stock, as the market discounted the price to reflect the time value of money and the remaining regulatory risks associated with the deal. This created a relatively stable trading range below the acquisition price, limiting significant upward or downward swings.

2. Mixed Fiscal Q3 2026 Financial Results.

Penumbra reported its fiscal Q3 2026 earnings (for the period ending September 30, 2026) on October 29, 2026, which presented a mixed financial picture. The company announced robust revenue growth of 15.6% year-over-year, reaching $410.1 million, surpassing analyst estimates of $401.41 million. This positive revenue performance was, however, partially offset by a diluted earnings per share (EPS) of $1.07, which missed the consensus estimate of $1.20, and a decrease in net income to $42.3 million from $45.9 million in fiscal Q3 2025. This combination of strong top-line growth and a bottom-line miss contributed to a balanced market reaction, preventing significant directional movement in the stock.

3. Positive Product Development Counterbalanced by Existing Valuation and Analyst Sentiment.

Several positive company-specific developments during the period, including the FDA clearance on October 20, 2026, for Penumbra's Lightning computer assisted vacuum thrombectomy (CAVT) technology to treat deep vein thrombosis (DVT) and favorable long-term clinical data from the STRIKE-PE study for CAVT treatment of pulmonary embolism, provided a positive catalyst for the stock. However, these advancements may have been largely factored into the stock's valuation, especially given the impending acquisition. Analyst sentiment remained largely "Hold" with average price targets in the range of $362.54 to $367.07, indicating that while there was recognized value, there was no strong conviction for substantial further upside, contributing to the stock's stability.

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Stock Movement Drivers

Fundamental Drivers

The 0.4% change in PEN stock from 7/31/2026 to 11/4/2026 was primarily driven by a 3.7% change in the company's Total Revenues ($ Mil).
(LTM values as of)731202611042026Change
Stock Price ($)321.19322.450.4%
Change Contribution By: 
Total Revenues ($ Mil)1,5051,5603.7%
Net Income Margin (%)10.7%10.1%-5.7%
P/E Multiple78.780.92.8%
Shares Outstanding (Mil)3939-0.1%
Cumulative Contribution0.4%

LTM = Last Twelve Months as of date shown

Market Drivers

7/31/2026 to 11/4/2026
ReturnCorrelation
PEN0.4% 
Market (SPY)2.6%21.4%
Sector (XLV)16.7%45.7%

Fundamental Drivers

The -1.2% change in PEN stock from 4/30/2026 to 11/4/2026 was primarily driven by a -20.5% change in the company's Net Income Margin (%).
(LTM values as of)430202611042026Change
Stock Price ($)326.48322.45-1.2%
Change Contribution By: 
Total Revenues ($ Mil)1,4041,56011.2%
Net Income Margin (%)12.7%10.1%-20.5%
P/E Multiple72.080.912.4%
Shares Outstanding (Mil)3939-0.5%
Cumulative Contribution-1.2%

LTM = Last Twelve Months as of date shown

Market Drivers

4/30/2026 to 11/4/2026
ReturnCorrelation
PEN-1.2% 
Market (SPY)7.0%7.8%
Sector (XLV)30.5%40.6%

Fundamental Drivers

The 41.8% change in PEN stock from 10/31/2025 to 11/4/2026 was primarily driven by a 35.4% change in the company's P/E Multiple.
(LTM values as of)1031202511042026Change
Stock Price ($)227.37322.4541.8%
Change Contribution By: 
Total Revenues ($ Mil)1,2801,56021.9%
Net Income Margin (%)11.5%10.1%-12.8%
P/E Multiple59.880.935.4%
Shares Outstanding (Mil)3939-1.4%
Cumulative Contribution41.8%

LTM = Last Twelve Months as of date shown

Market Drivers

10/31/2025 to 11/4/2026
ReturnCorrelation
PEN41.8% 
Market (SPY)13.4%3.0%
Sector (XLV)33.2%14.3%

Fundamental Drivers

The 68.7% change in PEN stock from 10/31/2023 to 11/4/2026 was primarily driven by a 224.0% change in the company's Net Income Margin (%).
(LTM values as of)1031202311042026Change
Stock Price ($)191.15322.4568.7%
Change Contribution By: 
Total Revenues ($ Mil)9381,56066.4%
Net Income Margin (%)3.1%10.1%224.0%
P/E Multiple251.580.9-67.8%
Shares Outstanding (Mil)3839-2.7%
Cumulative Contribution68.7%

LTM = Last Twelve Months as of date shown

Market Drivers

10/31/2023 to 11/4/2026
ReturnCorrelation
PEN68.7% 
Market (SPY)89.7%24.4%
Sector (XLV)59.5%25.0%

Return vs. Risk

Price Returns Compared

 202120222023202420252026Total [1]
Returns
PEN Return64%-23%13%-6%31%4%84%
Peers Return8%-4%12%18%19%-2%61%
S&P 500 Return27%-19%24%23%16%11%102%

Monthly Win Rates [3]
PEN Win Rate58%50%67%33%50%45% 
Peers Win Rate52%52%54%58%62%50% 
S&P 500 Win Rate75%42%67%75%67%36% 

Max Drawdowns [4]
PEN Max Drawdown-24%-60%-47%-40%-26%-12% 
Peers Max Drawdown-18%-25%-17%-11%-14%-32% 
S&P 500 Max Drawdown-5%-25%-10%-8%-19%-9% 


[1] Cumulative total returns since the beginning of 2021
[2] Peers: SYK, MDT, JNJ, BSX. See PEN Returns vs. Peers.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 11/4/2026 (YTD)

How Low Can It Go

EventPENS&P 500
2025 US Tariff Shock
  % Loss-16.6%-18.8%
  % Gain to Breakeven19.9%23.1%
  Time to Breakeven183 days79 days
Summer-Fall 2023 Five Percent Yield Shock
  % Loss-39.9%-9.5%
  % Gain to Breakeven66.4%10.5%
  Time to Breakeven467 days24 days
2022 Inflation Shock & Fed Tightening
  % Loss-59.1%-24.5%
  % Gain to Breakeven144.6%32.4%
  Time to Breakeven299 days427 days
2020 COVID-19 Crash
  % Loss-35.8%-33.7%
  % Gain to Breakeven55.8%50.9%
  Time to Breakeven107 days140 days
Q4 2018 Fed Policy Error / Growth Scare
  % Loss-19.6%-19.2%
  % Gain to Breakeven24.4%23.8%
  Time to Breakeven25 days105 days
2016-2017 Trump Reflation Bond Selloff
  % Loss-22.8%-3.7%
  % Gain to Breakeven29.6%3.9%
  Time to Breakeven103 days6 days

Compare to SYK, MDT, JNJ, BSX

In The Past

Penumbra's stock fell -16.6% during the 2025 US Tariff Shock. Such a loss loss requires a 19.9% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

EventPENS&P 500
Summer-Fall 2023 Five Percent Yield Shock
  % Loss-39.9%-9.5%
  % Gain to Breakeven66.4%10.5%
  Time to Breakeven467 days24 days
2022 Inflation Shock & Fed Tightening
  % Loss-59.1%-24.5%
  % Gain to Breakeven144.6%32.4%
  Time to Breakeven299 days427 days
2020 COVID-19 Crash
  % Loss-35.8%-33.7%
  % Gain to Breakeven55.8%50.9%
  Time to Breakeven107 days140 days
2016-2017 Trump Reflation Bond Selloff
  % Loss-22.8%-3.7%
  % Gain to Breakeven29.6%3.9%
  Time to Breakeven103 days6 days

Compare to SYK, MDT, JNJ, BSX

In The Past

Penumbra's stock fell -16.6% during the 2025 US Tariff Shock. Such a loss loss requires a 19.9% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

About Penumbra (PEN)

Penumbra, Inc. (PEN) is a medical device company that designs, develops, manufactures, and markets a comprehensive portfolio of innovative products. The company primarily focuses on advanced technologies for neurovascular and peripheral vascular interventions, aiming to improve patient outcomes for critical conditions such as stroke, aneurysms, and various vascular diseases.

The company's core product lines include aspiration-based thrombectomy systems, like the Penumbra System and Indigo System, which are vital for mechanical thrombectomy to remove blood clots in neurovascular and peripheral vascular applications. Penumbra also provides neurovascular embolization coiling systems (e.g., Penumbra Coil 400, POD400) to treat aneurysms and other lesions, alongside neurovascular access systems (e.g., Neuron, BENCHMARK) that facilitate intracranial access for various therapies. Additionally, they offer detachable embolic coils and occlusion devices, such as the Ruby Coil and POD, for peripheral vessel embolization.

Beyond these interventional tools, Penumbra develops neurosurgical aspiration devices for tissue and fluid removal. The company has also ventured into immersive computer-based technologies, notably the Real Immersive System, designed to promote health, motor function, and cognition. Penumbra sells its products globally through direct sales organizations and distributors, primarily serving hospitals and medical professionals specializing in neurology, neurosurgery, interventional radiology, and vascular medicine.

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Medtronic for neurovascular and peripheral vascular medical devices.

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  • Aspiration-based Thrombectomy Systems: Devices like the Penumbra System and Indigo System used for mechanical thrombectomy to remove blood clots from neurovascular and peripheral vessels.
  • Neurovascular Embolization Coiling Systems: Systems such as Penumbra Coil 400 designed to treat aneurysms and other neurovascular lesions.
  • Neurovascular Access Systems: Devices like Neuron and BENCHMARK that provide intracranial access for various neurovascular therapies.
  • Neurosurgical Aspiration Tools: The Artemis Neuro Evacuation Device for removing tissue and fluids in neurosurgery.
  • Peripheral Embolization Devices: Detachable coils (e.g., Ruby Coil) and occlusion devices (e.g., POD) for blocking blood flow in peripheral vessels.
  • Immersive Therapeutics: The Real Immersive System, which uses computer-based technologies to promote health, motor function, and cognition.

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Penumbra (PEN) sells primarily to other companies rather than individuals. As a designer, developer, manufacturer, and marketer of specialized medical devices, its major customers are healthcare institutions such as hospitals, surgical centers, and specialized clinics (e.g., those performing neurovascular and peripheral interventions) that utilize its advanced medical technologies.

The provided company description indicates that Penumbra sells its products through direct sales organizations and distributors, who then supply these medical devices to the aforementioned healthcare providers. However, the background information does not list the names of specific customer companies or distributors.

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Adam Elsesser, Chairman and Chief Executive Officer

Adam Elsesser co-founded Penumbra, Inc. in 2004 and has served as its Chief Executive Officer and a director since its inception, and as Chairman since January 2015. Before co-founding Penumbra, he led SMART Therapeutics, Inc., a medical device company focused on neuro-intervention, as its Chief Executive Officer from 2000 to 2002. Following SMART Therapeutics' acquisition by Boston Scientific Corporation, he served as President of SMART Therapeutics within Boston Scientific Corporation from 2002 to 2005. Prior to his work in the medical device industry, Mr. Elsesser was a partner in the law firm of Shartsis Friese LLP.

Maggie Yuen, Chief Financial Officer

Maggie Yuen manages the financial strategy that supports Penumbra, Inc.'s aggressive research and development spending and market expansion. She is listed as the Chief Financial Officer on the company's leadership page.

Arani Bose, M.D., Co-Founder, Chief Innovator and Director

Dr. Arani Bose co-founded Penumbra, Inc. in 2004 and has been its Chief Innovator since 2004. He previously served as Chief Medical Officer and Chairman of Penumbra, Inc. from 2005 until 2015. Dr. Bose also founded Smart Therapeutics, Inc., where he developed neurovascular stents, and served as its Chairman. He was an Assistant Professor of Radiology and Neurology at the New York University School of Medicine.

Shruthi Narayan, President

Shruthi Narayan was promoted to President in September 2025, where she oversees the company's global operations and growth initiatives.

James F. Benenati, M.D., FSIR, Chief Medical Officer

Dr. James F. Benenati joined Penumbra, Inc. as Chief Medical Officer in September 2020. In this role, he contributes to clinical and medical affairs strategies and advises on global commercialization and market development activities. Prior to joining Penumbra, he practiced interventional radiology at the Miami Cardiac & Vascular Institute for over 30 years. He also served as the Director of the Fellowship Program and Medical Director of the Non-Invasive Vascular Laboratory at the institute.

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Here are the key risks to Penumbra's business:

1. Regulatory and Product Liability Risks

As a medical device company, Penumbra operates in a highly regulated environment, subject to stringent domestic and international medical device regulations. Non-compliance, unforeseen issues with product safety or efficacy, or the need to meet evolving global regulatory standards (such as the EU MDR) can impede product approvals, hinder development and manufacturing activities, and result in costly product recalls or significant legal liabilities. The company has faced past allegations of product design defects, such as with its Jet 7 Xtra Flex catheter, which led to a voluntary recall and associated legal scrutiny, highlighting the tangible nature of this risk.

2. Intense Competition and Technological Obsolescence

Penumbra operates in a highly competitive medical device market characterized by rapid technological advancements and short product life cycles. The company faces significant competition from larger, well-capitalized players with extensive resources and established distribution networks, including companies like Boston Scientific, Medtronic, and Stryker. To maintain its market position and avoid technological obsolescence, Penumbra must continuously innovate and invest significantly in research and development. Failure to successfully develop and commercialize new products or to effectively compete against superior or more cost-effective technologies introduced by rivals could adversely affect its market share and financial performance.

3. Reimbursement Landscape Changes

The demand for Penumbra's medical devices is significantly influenced by the ability of healthcare providers to obtain adequate reimbursement for procedures utilizing these products. Reimbursement levels vary substantially across different countries and regions, originating from government-sponsored and private health insurance plans. Changes in healthcare policies, shifts in private insurance coverage decisions, or requirements for additional clinical data before or after recognizing coverage and reimbursement for Penumbra's products could negatively impact their adoption and sales.

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Here are the addressable market sizes for Penumbra's main products and services:

  • Neurovascular Thrombectomy Systems (for ischemic stroke):
    • The global neurothrombectomy devices market size was estimated at USD 825.92 million in 2025 and is predicted to reach approximately USD 1,494.32 million by 2034. North America accounted for 38.12% of the neurovascular thrombectomy devices market revenue in 2025.
    • Another source reported the global neurovascular thrombectomy devices market size at USD 3.00 billion in 2024, projected to reach USD 5.00 billion by 2032.
  • Neurovascular Embolization Coiling Systems (for aneurysms and other neurovascular lesions):
    • The global neurovascular embolization market was valued at USD 1.4 billion in 2022 and is estimated to reach USD 2.5 billion by 2032. The U.S. neurovascular embolization market accounted for USD 503 million in 2022.
    • The global neuroendovascular coil market was estimated at USD 1.22 billion in 2024 and is expected to reach USD 1.98 billion by 2030. The USA neuroendovascular coil market reached USD 0.46 billion in 2024.
    • The global intracranial aneurysm market was valued at USD 1.74 billion in 2025 and is projected to grow to USD 2.95 billion by 2034. Endovascular coiling, a treatment type, accounted for 66.7% market share in 2025 for the intracranial aneurysm market and is expected to exceed USD 2.7 billion by 2035. The U.S. intracranial aneurysm market was USD 637.8 million in 2025.
  • Peripheral Aspiration-Based Thrombectomy Systems and Peripheral Embolization Devices:
    • The global peripheral thrombectomy devices market size was valued at USD 684.99 million in 2025 and is expected to reach USD 1,134.50 million by 2033. The U.S. peripheral vascular thrombectomy devices market captured 42% of the revenue share in 2025 within North America.
    • The global peripheral embolization devices market size was valued at USD 11.50 billion in 2022 and is expected to reach USD 6.10 billion by 2030, growing at a CAGR of 11.50%. Another report states the peripheral embolization device market was valued at USD 696.45 million in 2025 and is expected to increase to USD 1,118.35 million by 2032. North America dominates this market.
  • Immersive Computer-Based Technologies and Immersive Therapeutics (Real Immersive System):
    • The global digital therapeutics market size was estimated at USD 7.88 billion in 2024 and is expected to reach approximately USD 56.76 billion by 2034. North America contributed the largest market share of 44.03% in 2023.
    • The global immersive technologies market size was valued at USD 53.29 billion in 2025 and is projected to grow to USD 500.27 billion by 2034. Healthcare and life sciences represent nearly 14% of this market share.
    • The Global Immersive Technology in Healthcare Market is projected to grow from USD 4.21 billion in 2025 to USD 12.48 billion by 2031.

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Expected Drivers of Future Revenue Growth for Penumbra (PEN)

Penumbra (PEN) is anticipated to drive future revenue growth over the next 2-3 years through several key strategies and product advancements:

  1. Expansion and Innovation in Computer Assisted Vacuum Thrombectomy (CAVT) Portfolio

    Penumbra expects significant growth from its expanding portfolio of Computer Assisted Vacuum Thrombectomy (CAVT) products. Recent and anticipated product launches, such as Lightning Bolt 16 and Lightning Flash 3.0, have received FDA clearance and are designed to enhance clot detection and removal. Furthermore, the Thunderbolt system, currently in the final stages of FDA review, is expected to stimulate the U.S. market, especially for stroke treatment. The company plans to launch multiple new CAVT products in the United States, targeting market share gains and growth across deep vein thrombosis, pulmonary embolism, and arterial applications.

  2. International Market Expansion

    The company is strategically focused on materially increasing its international revenues and profitability over the next three years. This includes expanding its presence, particularly in Europe, by introducing advanced thrombectomy products, including its first-generation computer-aided devices, to global teams. Penumbra anticipates double-digit growth in its international business, with expected alleviation of China-specific headwinds by early next year.

  3. Growing Adoption of U.S. Thrombectomy and Embolization Products

    Penumbra foresees continued strong demand and increased market penetration for its thrombectomy and embolization products in the U.S. This growth is being fueled by robust demand for its U.S. VTE (Venous Thromboembolism) franchise and embolization solutions. Strategic investments, such as the dedicated expansion of the U.S. Peripheral Embolization sales team and the successful launch of products like Ruby XL, have already resulted in significant sequential growth in embolization revenue.

  4. Positive Clinical Data Driving Product Adoption

    The outcomes from landmark clinical trials, such as the STORM-PE randomized controlled trial, are crucial for accelerating product adoption. The STORM-PE results demonstrated that CAVT, combined with anticoagulation, significantly improved functional outcomes for patients with pulmonary embolism. These findings are expected to build physician confidence and lead to a more rapid integration of Penumbra's advanced thrombectomy systems into hospital protocols.

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Share Repurchases

  • Penumbra's Board of Directors authorized a share repurchase program of up to $200 million on August 5, 2024, set to expire on July 31, 2025.
  • As part of this authorization, Penumbra entered into an accelerated share repurchase agreement (ASR) on August 12, 2024, to repurchase $100 million of its common stock.
  • An initial delivery of approximately 474,000 shares of Penumbra's common stock was received on August 13, 2024, with the final settlement of the ASR expected in the third quarter of 2024.

Inbound Investments

  • Boston Scientific Corporation announced in January 2026 its definitive agreement to acquire Penumbra, Inc. for approximately $14.5 billion to $15 billion in a cash and stock deal.

Capital Expenditures

  • Penumbra's capital expenditures were approximately $19.46 million for the last 12 months as of December 31, 2024.
  • Annual capital expenditures were $13 million in 2023, $14 million in 2024, and $5.47 million in 2025.
  • Strategic capital investments have been directed towards establishing facilities, such as the Costa Rica facility, to support global market expansion.

Better Bets vs. Penumbra (PEN)

Peer Outperformance in Health Care Equipment

PEN has outperformed 71% of its 49 Health Care Equipment peers over 5Y. Among the peers that beat it are UFPT, LMAT and ISRG. Health Care Equipment ranks 5th of 10 industries in Health Care by median 5Y return.
Share of Health Care Equipment constituents that PEN has outperformed, by holding period. Peers without a full price history over a given window are excluded from that window.
1Y
70%
of 54 industry peers · 37.2% return
3Y
74%
of 53 industry peers · 63.0% return
5Y
71%
of 49 industry peers · 12.0% return
Health Care Equipment peers with revenue growth within 4pp of PEN's that beat it on at least 2 of 3 windows, and by at least 20pp over 5Y. Growth is matched by construction, so the gap is largely a re-rating gap. The multiple column is the context for it.
Ticker Name Rev Growth 3Y Avg P/E 1Y3Y5Y 5Y Gap
PEN Penumbra 16.2% 80.9x 37.2%63.0%12.0% —
UFPT UFP Technologies 18.8% 35.3x 47.9%130.4%407.7% +396pp
LMAT LeMaitre Vascular 14.0% 30.6x 1.8%86.4%77.2% +65pp
ISRG Intuitive Surgical 19.2% 56.9x -10.5%73.1%32.7% +21pp
Price returns, excluding dividends. P/E shown for context only and not used for matching.
Median price return by industry across the Health Care sector, ranked by 5Y. Health Care Equipment is PEN's own industry. Use this to see which corners of the sector have carried the returns.
Industry Names 1Y med3Y med5Y med Top 3 by 5Y
Health Care Distributors 6 13.4%63.7%103.3% CAH 490% · MCK 391% · COR 194%
Health Care Services 20 44.0%33.3%11.6% HIMS 220% · RDNT 148% · DGX 96%
Managed Health Care 8 44.6%5.6%0.6% OSCR 107% · HQY 59% · ELV 11%
Health Care Facilities 25 16.9%18.4%-3.0% THC 302% · NHC 241% · EHC 202%
Health Care Equipment ← 50 14.4%18.7%-15.0% UFPT 408% · GKOS 348% · PLSE 147%
Pharmaceuticals 60 -5.1%8.2%-35.2% LQDA 999% · KNSA 546% · LLY 448%
Health Care Supplies 11 34.9%23.0%-36.1% LNTH 267% · HAE 76% · MMSI 33%
Life Sciences Tools & Services 108 -6.2%-10.3%-74.1% AXGN 288% · NTRA 253% · MEDP 189%
Biotechnology 364 -21.1%-31.5%-81.7% ELVN 1112% · TRVI 1046% · DNTH 930%
Health Care Technology 21 -23.4%-56.5%-82.3% VEEV -3% · DOCS -52%
Median of constituents with a full price history over each window. Top names are limited to companies above $2B market cap.

Latest Trefis Analyses

Recent Active Movers

Peer Comparisons

Peers to compare with:

Financials

PENSYKMDTJNJBSXMedian
NamePenumbra Stryker MedtronicJohnson .Boston S. 
Mkt Price322.49339.89104.98278.9045.99278.90
Mkt Cap12.7129.9134.4672.066.6129.9
Rev LTM1,56026,30037,54199,33521,06926,300
Op Inc LTM1895,7347,14725,5254,3385,734
FCF LTM2004,5736,13219,5951,5164,573
FCF 3Y Avg1623,9505,52719,1002,3253,950
CFO LTM2615,4468,03526,1594,2345,446
CFO 3Y Avg2064,7067,36025,1703,9324,706

Growth & Margins

PENSYKMDTJNJBSXMedian
NamePenumbra Stryker MedtronicJohnson .Boston S. 
Rev Chg LTM17.0%7.9%9.8%7.8%8.9%8.9%
Rev Chg 3Y Avg16.2%9.8%6.0%5.9%15.4%9.8%
Rev Chg Q15.6%7.6%13.7%5.9%1.4%7.6%
QoQ Delta Rev Chg LTM3.7%1.8%3.2%1.4%0.3%1.8%
Op Inc Chg LTM9.5%19.8%7.5%7.9%16.6%9.5%
Op Inc Chg 3Y Avg52.4%15.8%6.3%4.4%23.2%15.8%
Op Mgn LTM12.1%21.8%19.0%25.7%20.6%20.6%
Op Mgn 3Y Avg10.6%20.5%18.5%25.4%19.2%19.2%
QoQ Delta Op Mgn LTM-0.3%0.1%0.3%-1.1%-0.4%-0.3%
CFO/Rev LTM16.7%20.7%21.4%26.3%20.1%20.7%
CFO/Rev 3Y Avg15.1%19.3%21.2%27.1%20.8%20.8%
FCF/Rev LTM12.8%17.4%16.3%19.7%7.2%16.3%
FCF/Rev 3Y Avg11.9%16.2%15.9%20.6%12.5%15.9%

Valuation

PENSYKMDTJNJBSXMedian
NamePenumbra Stryker MedtronicJohnson .Boston S. 
Mkt Cap12.7129.9134.4672.066.6129.9
P/S8.14.93.66.83.24.9
P/Op Inc67.122.718.826.315.422.7
P/EBIT60.822.818.335.916.522.8
P/E80.935.925.741.819.035.9
P/CFO48.723.916.725.715.723.9
Total Yield1.2%3.8%6.6%4.3%5.3%4.3%
Dividend Yield0.0%1.0%2.7%1.9%0.0%1.0%
FCF Yield 3Y Avg1.6%3.2%5.3%4.0%2.1%3.2%
D/E0.00.10.20.10.20.1
Net D/E-0.00.10.10.00.20.1

Returns

PENSYKMDTJNJBSXMedian
NamePenumbra Stryker MedtronicJohnson .Boston S. 
1M Rtn1.7%19.2%19.3%10.3%8.5%10.3%
3M Rtn-0.2%1.2%23.1%8.8%-3.7%1.2%
6M Rtn-0.5%16.9%37.6%25.5%-17.9%16.9%
12M Rtn37.2%-5.2%20.0%52.6%-53.5%20.0%
3Y Rtn63.0%26.7%59.6%100.7%-12.5%59.6%
1M Excs Rtn4.9%25.4%23.7%12.7%12.2%12.7%
3M Excs Rtn1.1%2.9%25.0%10.9%-4.9%2.9%
6M Excs Rtn-3.3%14.2%34.9%22.7%-20.7%14.2%
12M Excs Rtn32.1%-14.5%9.8%42.6%-63.9%9.8%
3Y Excs Rtn-13.1%-48.4%-16.1%24.2%-90.1%-16.1%

Financials

Segment Financials

Revenue by Segment
$ Mil20252024202320222021
Thrombectomy948815677511438
Embolization and Access456379381336310
Total1,4041,1951,059847748


Price Behavior

Price Behavior
Market Price$322.45 
Market Cap ($ Bil)12.7 
First Trading Date09/18/2015 
Distance from 52W High-10.3% 
   50 Days200 Days
DMA Price$320.31$327.02
DMA Trendindeterminateindeterminate
Distance from DMA0.7%-1.4%
 3M1YR
Volatility7.7%26.8%
Downside Capture3.950.56
Upside Capture-5.4842.20
Correlation (S&P 500)10.6%2.6%
PEN Betas & Captures as of 10/31/2026

 1M2M3M6M1Y3Y
Beta0.060.070.140.040.060.57
Up Beta0.350.210.22-0.010.020.78
Down Beta0.420.280.410.13-0.430.26
Up Capture-9%-6%3%0%33%32%
Bmk +ve Days12182862130427
Stock +ve Days10203467129373
Down Capture-11%5%8%7%7%80%
Bmk -ve Days10253664121325
Stock -ve Days12233059122377

[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with PEN
PEN42.8%26.8%1.28-
Sector ETF (XLV)33.1%16.7%1.5314.3%
Equity (SPY)13.2%12.9%0.683.0%
Gold (GLD)1.0%28.8%0.033.5%
Commodities (DBC)35.9%21.2%1.34-5.2%
Real Estate (VNQ)14.3%14.1%0.709.3%
Bitcoin (BTCUSD)-28.2%43.4%-0.65-12.0%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 5-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with PEN
PEN3.5%40.3%0.19-
Sector ETF (XLV)9.3%15.3%0.4036.6%
Equity (SPY)12.5%17.2%0.5540.7%
Gold (GLD)17.3%19.1%0.736.2%
Commodities (DBC)8.0%19.6%0.294.7%
Real Estate (VNQ)1.8%18.9%-0.0134.8%
Bitcoin (BTCUSD)5.5%51.5%0.2919.5%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 10-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with PEN
PEN16.1%40.9%0.50-
Sector ETF (XLV)12.5%16.8%0.6140.0%
Equity (SPY)15.4%18.0%0.7342.2%
Gold (GLD)11.9%16.5%0.596.7%
Commodities (DBC)7.4%18.1%0.3310.3%
Real Estate (VNQ)5.7%20.7%0.2334.0%
Bitcoin (BTCUSD)61.0%66.2%1.019.6%

Smart multi-asset allocation framework can stack odds in your favor. Learn How

Short Interest

Short Interest: As Of Date10152026
Short Interest: Shares Quantity2.3 Mil
Short Interest: % Change Since 93020260.8%
Average Daily Volume0.3 Mil
Days-to-Cover Short Interest6.8 days
Basic Shares Quantity39.4 Mil
Short % of Basic Shares5.7%

Earnings Returns History

Updated 11/3/2026
Expand for More
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
10/29/2026-0.9%  
7/30/20260.4%1.6%0.6%
5/6/20260.1%-0.5%-1.1%
2/25/20261.0%0.3%-0.7%
11/5/202517.3%24.3%30.7%
7/29/202511.9%5.7%17.5%
4/23/20257.0%5.0%-4.3%
2/18/202512.0%3.9%3.1%
...
SUMMARY STATS   
# Positive141212
# Negative101111
Median Positive6.8%5.4%15.3%
Median Negative-3.4%-4.1%-6.5%
Max Positive17.3%25.7%39.6%
Max Negative-9.7%-19.0%-16.2%
Collapse to Preview
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
10/29/2026-0.9%  
7/30/20260.4%1.6%0.6%
5/6/20260.1%-0.5%-1.1%
2/25/20261.0%0.3%-0.7%
11/5/202517.3%24.3%30.7%
7/29/202511.9%5.7%17.5%
4/23/20257.0%5.0%-4.3%
2/18/202512.0%3.9%3.1%
10/30/20248.3%10.6%15.5%
7/30/2024-3.5%-1.0%15.8%
5/7/2024-3.3%-0.6%-6.5%
2/22/2024-9.3%-10.6%-14.4%
11/2/2023-0.2%-7.3%15.3%
8/1/2023-9.7%-16.9%-11.5%
5/2/20237.0%11.9%11.7%
2/23/20232.2%-0.3%4.9%
11/3/20226.7%25.7%39.6%
8/5/202216.6%18.7%15.3%
5/3/2022-1.9%-19.0%-16.2%
2/22/2022-5.8%3.5%-4.7%
11/3/20213.8%-2.8%-14.2%
8/9/2021-2.0%-4.1%3.1%
5/4/2021-5.4%-8.4%-11.2%
2/23/20213.0%0.9%-6.5%
SUMMARY STATS   
# Positive141212
# Negative101111
Median Positive6.8%5.4%15.3%
Median Negative-3.4%-4.1%-6.5%
Max Positive17.3%25.7%39.6%
Max Negative-9.7%-19.0%-16.2%

SEC Filings

Expand for More
Report DateFiling DateFiling
09/30/202610/29/202610-Q
06/30/202607/30/202610-Q
03/31/202605/06/202610-Q
12/31/202502/25/202610-K
09/30/202511/05/202510-Q
06/30/202507/29/202510-Q
03/31/202504/23/202510-Q
12/31/202402/18/202510-K
09/30/202410/30/202410-Q
06/30/202407/30/202410-Q
03/31/202405/07/202410-Q
12/31/202302/22/202410-K
09/30/202311/02/202310-Q
06/30/202308/01/202310-Q
03/31/202305/02/202310-Q
12/31/202202/23/202310-K
Collapse to Preview
Report DateFiling DateFiling
09/30/202610/29/202610-Q
06/30/202607/30/202610-Q
03/31/202605/06/202610-Q
12/31/202502/25/202610-K
09/30/202511/05/202510-Q
06/30/202507/29/202510-Q
03/31/202504/23/202510-Q
12/31/202402/18/202510-K
09/30/202410/30/202410-Q
06/30/202407/30/202410-Q
03/31/202405/07/202410-Q
12/31/202302/22/202410-K
09/30/202311/02/202310-Q
06/30/202308/01/202310-Q
03/31/202305/02/202310-Q
12/31/202202/23/202310-K
09/30/202211/03/202210-Q
06/30/202208/05/202210-Q
03/31/202205/03/202210-Q
12/31/202102/22/202210-K
09/30/202111/03/202110-Q
06/30/202108/09/202110-Q
03/31/202105/04/202110-Q
12/31/202002/23/202110-K
09/30/202011/02/202010-Q
06/30/202008/03/202010-Q
03/31/202005/07/202010-Q
12/31/201902/26/202010-K

Insider Activity

Updated 9/17/2026
Expand for More
#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Grewal, Harpreet DirectSell4062026328.2210032,8222,861,750Form
2Yuen, MaggieChief Financial OfficerDirectSell3042026342.302,432832,4746,282,232Form
3Wilder, Thomas DirectSell1062026310.72186  Form
4Bose, AraniLLCSell12152025308.8215,0004,632,29279,818,099Form
5Roberts, JohannaEVP, Gen. Counsel & SecretaryDirectSell12092025300.1330090,03919,159,099Form
Collapse to Preview
#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Grewal, Harpreet DirectSell4062026328.2210032,8222,861,750Form
2Yuen, MaggieChief Financial OfficerDirectSell3042026342.302,432832,4746,282,232Form
3Wilder, Thomas DirectSell1062026310.72186  Form
4Bose, AraniLLCSell12152025308.8215,0004,632,29279,818,099Form
5Roberts, JohannaEVP, Gen. Counsel & SecretaryDirectSell12092025300.1330090,03919,159,099Form
6Grewal, Harpreet DirectSell12032025292.9810029,2982,465,720Form
7Roberts, JohannaEVP, Gen. Counsel & SecretaryDirectSell12032025294.94600176,96618,916,497Form
8Roberts, JohannaEVP, Gen. Counsel & SecretaryDirectSell11262025300.061,800540,10819,424,684Form
9Bose, AraniLLCSell11262025300.197,5002,251,42582,630,600Form
10Bose, AraniLLCSell11252025290.567,5002,179,21282,159,507Form
11Roberts, JohannaEVP, Gen. Counsel & SecretaryDirectSell11122025266.98600160,18916,995,213Form
12Grewal, Harpreet DirectSell11062025227.5818642,3301,938,071Form
13Grewal, Harpreet DirectSell10032025248.6118646,2412,163,404Form
14Roberts, JohannaEVP, Gen. Counsel & SecretaryDirectSell10032025249.70600149,82016,045,016Form
15Wilder, Thomas DirectSell10032025253.9318647,23147,231Form
16Elsesser, AdamCEODirectSell9042025269.6515,8004,260,45749,200,188Form
17Grewal, Harpreet DirectSell9042025272.1918650,6272,419,225Form
18Roberts, JohannaEVP, Gen. Counsel & SecretaryDirectSell9042025270.58600162,34717,548,904Form

Investor Activity (13F)

Updated Nov 5, 2026
13F holdings as of Mar 31, 2026 (Q1 2026)

Active managers (13F portfolio over $250M, at least 3 holdings) with a position over $5M that is either over 10% of their portfolio or held in a concentrated book of 50 or fewer total positions. Index/ETF, sovereign, bank, community-bank and charitable/donor-advised filers are excluded.

Active ManagerValue% of PortfolioTotal PositionsQoQFiling
Decagon Asset Management LLP$55.0 Mil14.3%74New13F
Slotnik Capital, LLC$33.2 Mil9.9%24New13F
Birnam Oak Advisors, LP$31.5 Mil8.7%43New13F
Sand Grove Capital Management LLP$28.5 Mil6.7%18New13F
PSquared Asset Management AG$14.0 Mil4.9%15New13F
Melqart Asset Management (UK) Ltd$26.9 Mil2.6%41New13F
Active ManagerValue% of PortfolioTotal PositionsQoQFiling
Decagon Asset Management LLP$55.0 Mil14.3%74New13F
Slotnik Capital, LLC$33.2 Mil9.9%24New13F
Birnam Oak Advisors, LP$31.5 Mil8.7%43New13F
Sand Grove Capital Management LLP$28.5 Mil6.7%18New13F
Melqart Asset Management (UK) Ltd$26.9 Mil2.6%41New13F
PSquared Asset Management AG$14.0 Mil4.9%15New13F
Active Manager
Active ManagerValue% of PortfolioTotal PositionsQoQFiling
Decagon Asset Management LLP$55.0 Mil14.3%74New13F
Slotnik Capital, LLC$33.2 Mil9.9%24New13F
Birnam Oak Advisors, LP$31.5 Mil8.7%43New13F
Sand Grove Capital Management LLP$28.5 Mil6.7%18New13F
Melqart Asset Management (UK) Ltd$26.9 Mil2.6%41New13F
PSquared Asset Management AG$14.0 Mil4.9%15New13F
Core Cache Last Updated: 11/4/2026