TransMedics (TMDX)


Market Price (8/21/2026): $90.85 | Market Cap: $3.1 BilSector: Health Care | Industry: Health Care Equipment

TransMedics (TMDX)


Market Price (8/21/2026): $90.85
Market Cap: $3.1 Bil
Sector: Health Care
Industry: Health Care Equipment

Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.

0

Attractive cash flow generation
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 22%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 12%

Megatrend and thematic drivers
Megatrends include Digital Health & Telemedicine, Biotechnology & Genomics, and Precision Medicine. Themes include Remote Patient Monitoring, Show more.

Weak multi-year price returns
2Y Excs Rtn is -84%, 3Y Excs Rtn is -28%

Expensive valuation multiples
P/EBITPrice/EBIT or Price/(Operating Income) ratio is 33x

Significant short interest
Short Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 22%

Key risks
TMDX key risks include [1] a class-action lawsuit alleging fraud and historical FDA scrutiny of its OCS device, Show more.

0 Attractive cash flow generation
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 22%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 12%
1 Megatrend and thematic drivers
Megatrends include Digital Health & Telemedicine, Biotechnology & Genomics, and Precision Medicine. Themes include Remote Patient Monitoring, Show more.
2 Weak multi-year price returns
2Y Excs Rtn is -84%, 3Y Excs Rtn is -28%
3 Expensive valuation multiples
P/EBITPrice/EBIT or Price/(Operating Income) ratio is 33x
4 Significant short interest
Short Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 22%
5 Key risks
TMDX key risks include [1] a class-action lawsuit alleging fraud and historical FDA scrutiny of its OCS device, Show more.

TMDX in ETFs

Weight = TMDX's share of each fund

VTI0.00%
ITOT0.00%
IWM0.09%
IJR0.17%
VB0.03%
SLYG0.34%
IJT0.34%
IWO0.19%
+10 more covered ETFs

Valuation & Metrics

Price Chart

Why The Stock Moved

Qualitative Assessment

AI Analysis | Feedback

Updated on 8/19/2026

TransMedics (TMDX) stock has lost about 10% since 4/30/2026 because of the following key factors:

1. Q2 2026 Earnings Miss on EPS and Operating Income. TransMedics reported adjusted earnings per share (EPS) of $0.44 for fiscal Q2 2026 (ended June 30, 2026), missing analysts' consensus estimates of $0.50 by $0.06. This also represented a decline from $0.92 EPS in fiscal Q2 2025. Concurrently, income from operations for fiscal Q2 2026 was $23.7 million, a notable decrease from $36.6 million in the same period of the prior year. This financial performance contributed to an 8.5% stock price drop to $73.86 on August 5, 2026.

2. Analyst Downgrades and Price Target Reductions. Following the company's fiscal Q1 2026 earnings report, Oppenheimer downgraded TransMedics Group's stock rating from "outperform" to "market perform" on May 6, 2026. After the fiscal Q2 2026 results were released, several investment firms reduced their price targets for TMDX. For example, Piper Sandler maintained an "overweight" rating but cut its price target from $120.00 to $100.00 on August 5, 2026, and Needham & Company LLC decreased its price target from $142.00 to $106.00 on August 3, 2026. These revisions by analysts likely dampened investor confidence.

Show more
Updated on 8/19/2026

TransMedics (TMDX) stock has lost about 10% since 4/30/2026 because of the following key factors:

1. Q2 2026 Earnings Miss on EPS and Operating Income. TransMedics reported adjusted earnings per share (EPS) of $0.44 for fiscal Q2 2026 (ended June 30, 2026), missing analysts' consensus estimates of $0.50 by $0.06. This also represented a decline from $0.92 EPS in fiscal Q2 2025. Concurrently, income from operations for fiscal Q2 2026 was $23.7 million, a notable decrease from $36.6 million in the same period of the prior year. This financial performance contributed to an 8.5% stock price drop to $73.86 on August 5, 2026.

2. Analyst Downgrades and Price Target Reductions. Following the company's fiscal Q1 2026 earnings report, Oppenheimer downgraded TransMedics Group's stock rating from "outperform" to "market perform" on May 6, 2026. After the fiscal Q2 2026 results were released, several investment firms reduced their price targets for TMDX. For example, Piper Sandler maintained an "overweight" rating but cut its price target from $120.00 to $100.00 on August 5, 2026, and Needham & Company LLC decreased its price target from $142.00 to $106.00 on August 3, 2026. These revisions by analysts likely dampened investor confidence.

3. Margin Compression Despite Strong Revenue Growth. While TransMedics achieved robust top-line growth, with fiscal Q2 2026 revenue increasing 21% year-over-year to $189.9 million, the decline in net income and operating profit compared to fiscal Q2 2025 indicates a compression in profit margins. This suggests that increased operational costs or strategic investments are currently outpacing the company's revenue expansion, impacting overall profitability.

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Stock Movement Drivers

Fundamental Drivers

The -9.9% change in TMDX stock from 4/30/2026 to 8/20/2026 was primarily driven by a -27.8% change in the company's Net Income Margin (%).
(LTM values as of)43020268202026Change
Stock Price ($)100.7990.85-9.9%
Change Contribution By: 
Total Revenues ($ Mil)60566810.4%
Net Income Margin (%)31.4%22.7%-27.8%
P/E Multiple18.120.714.2%
Shares Outstanding (Mil)3435-1.0%
Cumulative Contribution-9.9%

LTM = Last Twelve Months as of date shown

Market Drivers

4/30/2026 to 8/20/2026
ReturnCorrelation
TMDX-9.9% 
Market (SPY)6.1%-0.7%
Sector (XLV)18.1%5.9%

Fundamental Drivers

The -32.2% change in TMDX stock from 1/31/2026 to 8/20/2026 was primarily driven by a -58.4% change in the company's P/E Multiple.
(LTM values as of)13120268202026Change
Stock Price ($)133.9790.85-32.2%
Change Contribution By: 
Total Revenues ($ Mil)56666818.0%
Net Income Margin (%)16.2%22.7%40.1%
P/E Multiple49.820.7-58.4%
Shares Outstanding (Mil)3435-1.4%
Cumulative Contribution-32.2%

LTM = Last Twelve Months as of date shown

Market Drivers

1/31/2026 to 8/20/2026
ReturnCorrelation
TMDX-32.2% 
Market (SPY)10.5%20.8%
Sector (XLV)11.9%20.5%

Fundamental Drivers

The -23.6% change in TMDX stock from 7/31/2025 to 8/20/2026 was primarily driven by a -63.2% change in the company's P/E Multiple.
(LTM values as of)73120258202026Change
Stock Price ($)118.9790.85-23.6%
Change Contribution By: 
Total Revenues ($ Mil)53166825.8%
Net Income Margin (%)13.5%22.7%68.2%
P/E Multiple56.320.7-63.2%
Shares Outstanding (Mil)3435-1.9%
Cumulative Contribution-23.6%

LTM = Last Twelve Months as of date shown

Market Drivers

7/31/2025 to 8/20/2026
ReturnCorrelation
TMDX-23.6% 
Market (SPY)21.7%26.1%
Sector (XLV)33.9%21.5%

Fundamental Drivers

The -2.5% change in TMDX stock from 7/31/2023 to 8/20/2026 was primarily driven by a -81.4% change in the company's P/S Multiple.
(LTM values as of)73120238202026Change
Stock Price ($)93.1890.85-2.5%
Change Contribution By: 
Total Revenues ($ Mil)119668461.1%
P/S Multiple25.24.7-81.4%
Shares Outstanding (Mil)3235-6.7%
Cumulative Contribution-2.5%

LTM = Last Twelve Months as of date shown

Market Drivers

7/31/2023 to 8/20/2026
ReturnCorrelation
TMDX-2.5% 
Market (SPY)72.5%27.9%
Sector (XLV)34.5%19.5%

Return vs. Risk

Price Returns Compared

 202120222023202420252026Total [1]
Returns
TMDX Return-4%222%28%-21%95%-23%372%
Peers Return-2%-32%1%22%12%28%17%
S&P 500 Return27%-19%24%23%16%13%105%

Monthly Win Rates [3]
TMDX Win Rate50%67%58%50%58%62% 
Peers Win Rate48%43%53%47%50%55% 
S&P 500 Win Rate75%42%67%75%67%50% 

Max Drawdowns [4]
TMDX Max Drawdown-60%-38%-62%-66%-28%-58% 
Peers Max Drawdown-49%-60%-59%-41%-39%-35% 
S&P 500 Max Drawdown-5%-25%-10%-8%-19%-9% 


[1] Cumulative total returns since the beginning of 2021
[2] Peers: CDNA, BLFS, INSP, IRTC, PEN. See TMDX Returns vs. Peers.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 8/20/2026 (YTD)

How Low Can It Go

EventTMDXS&P 500
2025 US Tariff Shock
  % Loss-19.0%-18.8%
  % Gain to Breakeven23.4%23.1%
  Time to Breakeven29 days79 days
Summer-Fall 2023 Five Percent Yield Shock
  % Loss-59.6%-9.5%
  % Gain to Breakeven147.5%10.5%
  Time to Breakeven162 days24 days
2022 Inflation Shock & Fed Tightening
  % Loss-38.2%-24.5%
  % Gain to Breakeven61.8%32.4%
  Time to Breakeven22 days427 days
2020 COVID-19 Crash
  % Loss-47.7%-33.7%
  % Gain to Breakeven91.1%50.9%
  Time to Breakeven309 days140 days

Compare to CDNA, BLFS, INSP, IRTC, PEN

In The Past

TransMedics's stock fell -19.0% during the 2025 US Tariff Shock. Such a loss loss requires a 23.4% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

EventTMDXS&P 500
Summer-Fall 2023 Five Percent Yield Shock
  % Loss-59.6%-9.5%
  % Gain to Breakeven147.5%10.5%
  Time to Breakeven162 days24 days
2022 Inflation Shock & Fed Tightening
  % Loss-38.2%-24.5%
  % Gain to Breakeven61.8%32.4%
  Time to Breakeven22 days427 days
2020 COVID-19 Crash
  % Loss-47.7%-33.7%
  % Gain to Breakeven91.1%50.9%
  Time to Breakeven309 days140 days

Compare to CDNA, BLFS, INSP, IRTC, PEN

In The Past

TransMedics's stock fell -19.0% during the 2025 US Tariff Shock. Such a loss loss requires a 23.4% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

About TransMedics (TMDX)

TransMedics Group, Inc. (TMDX) is a commercial-stage medical technology company revolutionizing organ transplant therapy for patients suffering from end-stage organ failure. The company's core innovation is its proprietary Organ Care System (OCS), a portable platform designed to preserve, optimize, and monitor donor organs outside of the human body.

The Organ Care System utilizes customized technology to replicate near-physiologic conditions for organs prior to transplantation. TransMedics offers specialized OCS products for various organs, including OCS LUNG for the preservation of standard criteria donor lungs, OCS Heart for extracorporeal perfusion and preservation of donor hearts, and OCS Liver for the preservation of donor livers. These systems aim to enhance the viability and availability of donor organs.

TransMedics serves the global organ transplantation market, with its primary customers being transplant centers and hospitals in the United States and internationally. By improving the quality and accessibility of donor organs, the company ultimately benefits patients awaiting critical, life-saving transplants for lungs, hearts, and livers.

AI Analysis | Feedback

Here are 1-3 brief analogies for TransMedics:

  • It's like GE HealthCare for donor organs, providing advanced, life-sustaining systems specifically for organs outside the body.
  • Think of it as the Intuitive Surgical of organ transplantation, developing high-tech systems that transform how organs are preserved and utilized.

AI Analysis | Feedback

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  • Organ Care System (OCS): A portable organ perfusion, optimization, and monitoring system that replicates near-physiologic conditions for donor organs outside the human body.
  • OCS LUNG: A component of the OCS specifically designed for the preservation of standard criteria donor lungs for double-lung transplantation.
  • OCS Heart: A technology within the OCS used for extracorporeal perfusion and preservation of donor hearts.
  • OCS Liver: A part of the OCS utilized for the preservation of donor livers.
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AI Analysis | Feedback

TransMedics (TMDX) sells specialized medical technology, the Organ Care System (OCS), which is used in the complex process of organ transplantation. Therefore, its customers are not individuals but rather medical institutions.

The major category of customers that TransMedics serves is:

  • Hospitals and Organ Transplant Centers: These are medical institutions, often large academic medical centers or specialized hospitals, that operate organ transplant programs for heart, lung, and liver recipients. They acquire TransMedics' OCS devices to improve the preservation, assessment, and utilization of donor organs, thereby aiming to expand the donor pool and enhance the success rates of transplantation procedures for end-stage organ failure patients.

AI Analysis | Feedback

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AI Analysis | Feedback

Waleed Hassanein, M.D. TransMedics Founder, President and CEO

Dr. Waleed Hassanein founded TransMedics in 1998 with the aim of revolutionizing organ transplant therapy. His pioneering clinical research led to the development of a new field of living organ preservation for transplantation. He earned his M.D. from Georgetown University School of Medicine and completed a cardiac surgery research fellowship at the West Roxbury VA Medical Center and Brigham and Women's Hospital. In 1998, his research on ex-vivo heart perfusion for transplantation was recognized by the American Association for Thoracic Surgery. Dr. Hassanein has been recognized as a top Global Thinker in Healthcare and received the Tribeca Disruptive Innovator Award in 2018. He has served as a director of the company since August 1998.

Gerardo Hernandez Omana Chief Financial Officer and Treasurer

Gerardo Hernandez Omana was appointed Chief Financial Officer and Treasurer of TransMedics, effective December 2, 2024. He brings over 25 years of experience in finance across the healthcare and consumer packaged goods sectors. Before joining TransMedics, he served as Vice President Finance, Head of Corporate Financial Planning and Analysis at Alnylam Pharmaceuticals. Prior to that, he spent nearly a decade at Shire, where he led corporate FP&A and was instrumental in the integration efforts following Shire's $62 billion acquisition by Takeda. Mr. Hernandez began his career at Unilever. He holds a Bachelor of Science degree in Finance from the University of Wisconsin–La Crosse and an MBA in Strategy & Economics from Fundação Getulio Vargas, São Paulo.

Tamer Khayal, M.D. Chief Commercial Officer

Dr. Tamer Khayal joined TransMedics in 2001 and has since taken on increasing responsibilities, culminating in his appointment as Chief Commercial Officer in January 2018. From 2007 to 2018, he served as Chief Medical Officer, overseeing global initiatives for clinical evidence, reimbursement, and integration programs to support the approval and adoption of the Organ Care System (OCS) technology. Before joining TransMedics, Dr. Khayal was the Director of Medical Affairs for Zentiva Middle East, a pharmaceutical company. He received his M.D. degree from Cairo University School of Medicine.

Anil Ranganath Senior Vice President, General Counsel and Corporate Secretary

Nicholas Corcoran Senior Vice President of Supply Chain and Operations

AI Analysis | Feedback

Here are the key risks to TransMedics (TMDX) business:

  1. Regulatory and Legal Scrutiny: TransMedics faces significant risks due to ongoing legal actions and allegations of fraudulent practices. A class-action lawsuit has been filed, accusing the company of using kickbacks, engaging in fraudulent overbilling, employing coercive tactics to boost business, and concealing safety issues. There are also allegations of steering rejected organs to certain users and inadequate training of technicians managing organs on their OCS devices. These accusations expose TransMedics to heightened regulatory risk, potential legal liabilities, and reputational damage.
  2. Competition and Market Dynamics: The company operates in a competitive environment with other players developing organ preservation technologies, such as XVIVO Perfusion, OrganOx, and Paragonix Technologies. While TransMedics currently holds a strong market position, particularly in warm perfusion organ transplants in the United States, there is a risk of market saturation and slowing growth as the U.S. market matures. The emergence of alternative organ preservation protocols, such as Normothermic Regional Perfusion (NRP), could also limit the total addressable market for TransMedics' Organ Care System (OCS). Furthermore, international expansion may be challenging due to differing reimbursement models and regulatory hurdles, and increased competition in specific organ markets (e.g., liver transplants) could pressure market share and pricing.
  3. Operational and Supply Chain Challenges: TransMedics faces operational risks related to scaling its manufacturing and sterilization capabilities to meet increasing demand for its products. The company's reliance on single-source suppliers for key components also poses a vulnerability. Additionally, its National OCS Program (NOP) involves a complex logistics infrastructure, including an owned aviation fleet, which introduces risks such as potential disruptions in aviation services, fluctuating fuel costs, maintenance issues, and the company's relatively limited experience in operating aircraft.

AI Analysis | Feedback

Increased competition in the ex-vivo organ perfusion market, particularly from companies like XVIVO Perfusion launching competing systems for various organs, directly challenging TransMedics' market share and leadership.

AI Analysis | Feedback

TransMedics (TMDX) offers its Organ Care System (OCS) for the preservation and assessment of donor organs. The addressable markets for its main products are as follows:

  • OCS Liver: The global Organ Care System market for liver is estimated to reach approximately $40.5 million by the end of 2026. In North America, the OCS market size for liver is projected to reach $17.4 million by 2026.

  • OCS Lung: The global Organ Care System market for lung is forecasted to generate approximately $5.6 million in revenue by 2026. For North America, the OCS lung market size is expected to grow to approximately $1.2 million by 2026.

  • OCS Heart: Specific addressable market size for the OCS Heart product was not explicitly quantified in the search results. However, TransMedics is actively working to expand the addressable heart transplant market through its OCS Heart technology and clinical trials.

AI Analysis | Feedback

TransMedics Group, Inc. (TMDX) is expected to drive future revenue growth over the next two to three years through several key initiatives and expansions:

  1. Increased Utilization of Organ Care System (OCS) in the U.S. The company anticipates continued revenue growth from the expanded adoption and utilization of its Organ Care System (OCS) for existing indications, particularly in liver and heart transplants, within its National OCS Program (NOP) in the United States. TransMedics reported a significant increase in U.S. OCS cases, reaching 5,139 in 2025, up 38% year-over-year.
  2. Expansion of Transplant Logistics Infrastructure. Revenue growth is also expected from the ongoing expansion and heightened utilization of TransMedics' proprietary transplant logistics services, including its aviation fleet. The company continues to invest in and leverage its robust logistics capabilities to support the National OCS Program, enhancing its ability to cover NOP missions requiring air transport.
  3. International Market Expansion. TransMedics is focused on expanding its NOP model into international markets. Active launches are underway in European markets, with Italy specifically highlighted for the first half of 2026. This international expansion is projected to significantly increase the company's total addressable market and contribute to future revenue growth.
  4. Introduction of New OCS Programs and Indications. The company is investing in and advancing its clinical pipeline to develop and launch new OCS programs and expand existing indications. This includes progress with programs such as OCS Kidney, for which the company aims to have the platform ready for FDA trials by early 2027, as well as the OCS ENHANCE Heart and DENOVO Lung programs. These new offerings are expected to broaden the clinical adoption of OCS technology and serve as significant revenue catalysts.

AI Analysis | Feedback

Share Issuance

  • TransMedics completed an underwritten public offering of 3,250,000 shares of its common stock at $40.00 per share in August 2022, generating gross proceeds of approximately $130 million.

Capital Expenditures

  • TransMedics reported capital expenditures of approximately $151.85 million in fiscal year 2023 and $129.74 million in fiscal year 2024.
  • For the trailing twelve months ending September 30, 2025, capital expenditures were approximately $57.34 million.
  • The primary focus of capital expenditures has been on ongoing upgrades to expand manufacturing, enhancing infrastructure for long-term scalability, and the expansion of its owned and operated aircraft fleet for organ transport, which reached 22 aircraft as of December 31, 2025. Investments also support research, clinical programs, and commercial infrastructure.

Better Bets vs. TransMedics (TMDX)

Peer Outperformance in Health Care Equipment

TMDX has outperformed 94% of its 49 Health Care Equipment peers over 5Y. Health Care Equipment ranks 5th of 10 industries in Health Care by median 5Y return.
Share of Health Care Equipment constituents that TMDX has outperformed, by holding period. Peers without a full price history over a given window are excluded from that window.
1Y
20%
of 55 industry peers · -25.5% return
3Y
78%
of 54 industry peers · 39.1% return
5Y
94%
of 49 industry peers · 237.5% return
No Health Care Equipment peer with a comparable growth profile has beaten TMDX by more than 20pp over 5Y.
Median price return by industry across the Health Care sector, ranked by 5Y. Health Care Equipment is TMDX's own industry. Use this to see which corners of the sector have carried the returns.
Industry Names 1Y med3Y med5Y med Top 3 by 5Y
Health Care Distributors 7 4.4%78.3%158.4% CAH 396% · MCK 329% · COR 178%
Health Care Services 20 19.5%43.7%9.3% HIMS 348% · RDNT 152% · DGX 75%
Managed Health Care 8 32.5%-5.1%-1.2% OSCR 132% · HQY 65% · ELV 13%
Health Care Facilities 24 8.3%-2.6%-16.6% THC 275% · NHC 266% · ENSG 123%
Health Care Equipment ← 50 -1.5%-8.1%-22.2% POCI 10975% · UFPT 368% · GKOS 278%
Health Care Supplies 12 37.0%-13.7%-25.8% LNTH 301% · HAE 82% · MMSI 30%
Pharmaceuticals 63 6.0%-1.5%-32.0% LQDA 2643% · INDV 1326% · ETON 1259%
Health Care Technology 21 -17.7%-55.4%-70.5% SPOK 117% · HSTM -3% · VEEV -22%
Life Sciences Tools & Services 108 -0.5%-33.8%-71.0% SNWV 1900% · ELMD 249% · MEDP 243%
Biotechnology 365 10.3%-24.9%-77.8% BRTX 110200% · CELZ 1729% · DNTH 1587%
Median of constituents with a full price history over each window. Top names are unfiltered by size in this render.

Latest Trefis Analyses

Recent Active Movers

Peer Comparisons

Peers to compare with:

Financials

TMDXCDNABLFSINSPIRTCPENMedian
NameTransMed.CareDx BioLife .Inspire .iRhythm Penumbra  
Mkt Price90.8546.9936.9761.27127.98323.7676.06
Mkt Cap3.12.41.81.84.212.72.8
Rev LTM6684581038998251,505747
Op Inc LTM82-4354-918729
FCF LTM7984-21173921682
FCF 3Y Avg-4225264-1516313
CFO LTM146941715786278120
CFO 3Y Avg9532111013120264

Growth & Margins

TMDXCDNABLFSINSPIRTCPENMedian
NameTransMed.CareDx BioLife .Inspire .iRhythm Penumbra  
Rev Chg LTM25.8%34.4%25.4%4.3%25.6%17.6%25.5%
Rev Chg 3Y Avg70.5%15.1%23.0%20.2%22.3%17.1%21.2%
Rev Chg Q20.7%52.2%21.5%-7.6%20.1%14.9%20.4%
QoQ Delta Rev Chg LTM5.1%11.0%5.1%-1.8%4.8%3.5%4.9%
Op Inc Chg LTM6.6%90.5%118.1%30.7%91.3%17.6%60.6%
Op Inc Chg 3Y Avg3,245.9%46.9%-25.3%164.6%29.0%79.2%63.0%
Op Mgn LTM12.2%-0.9%2.9%6.0%-1.1%12.4%4.5%
Op Mgn 3Y Avg8.8%-14.3%-8.9%2.9%-12.8%10.5%-3.0%
QoQ Delta Op Mgn LTM-2.6%2.8%18.1%0.4%3.6%-0.4%1.6%
CFO/Rev LTM21.8%20.4%16.4%17.5%10.4%18.5%18.0%
CFO/Rev 3Y Avg16.7%6.9%11.7%11.8%3.3%15.2%11.8%
FCF/Rev LTM11.8%18.3%-2.2%13.0%4.7%14.3%12.4%
FCF/Rev 3Y Avg-15.5%4.8%1.2%7.2%-3.7%12.2%3.0%

Valuation

TMDXCDNABLFSINSPIRTCPENMedian
NameTransMed.CareDx BioLife .Inspire .iRhythm Penumbra  
Mkt Cap3.12.41.81.84.212.72.8
P/S4.75.317.62.05.18.55.2
P/Op Inc38.5-571.6606.032.6-470.968.035.6
P/EBIT33.5-571.6606.028.323,651.162.147.8
P/E20.721.831.213.1-301.979.321.2
P/CFO21.525.8107.011.249.045.935.8
Total Yield4.8%4.6%3.2%7.6%-0.3%1.3%3.9%
Dividend Yield0.0%0.0%0.0%0.0%0.0%0.0%0.0%
FCF Yield 3Y Avg-0.2%1.4%0.2%3.7%-0.5%1.6%0.8%
D/E0.30.00.00.00.20.00.0
Net D/E0.1-0.1-0.0-0.20.0-0.0-0.0

Returns

TMDXCDNABLFSINSPIRTCPENMedian
NameTransMed.CareDx BioLife .Inspire .iRhythm Penumbra  
1M Rtn22.3%21.9%26.7%16.7%17.4%2.0%19.7%
3M Rtn32.0%117.8%49.4%36.9%8.6%-1.3%34.5%
6M Rtn-31.6%136.5%59.1%2.5%-19.4%-5.0%-1.2%
12M Rtn-25.5%286.1%48.1%-34.2%-21.6%26.6%2.5%
3Y Rtn39.1%445.1%237.9%-71.9%19.1%30.2%34.7%
1M Excs Rtn25.7%22.5%16.8%19.7%18.8%0.4%19.2%
3M Excs Rtn30.8%119.4%51.2%36.0%6.6%-3.9%33.4%
6M Excs Rtn-43.0%125.1%47.8%-8.9%-30.8%-16.3%-12.6%
12M Excs Rtn-45.1%287.0%31.5%-51.1%-38.4%8.7%-14.9%
3Y Excs Rtn-28.0%314.3%129.1%-147.3%-60.1%-47.7%-37.8%

Financials

Segment Financials

Revenue by Segment
$ Mil20252024202320222021
Liver revenue461310152462
Heart revenue126110733818
Lung revenue151812911
Service revenue unrelated to Organ Care System (OCS) transplant445  
Total6054422429330


Price Behavior

Price Behavior
Market Price$90.85 
Market Cap ($ Bil)3.1 
First Trading Date05/02/2019 
Distance from 52W High-39.6% 
   50 Days200 Days
DMA Price$77.72$106.46
DMA Trenddownup
Distance from DMA16.9%-14.7%
 3M1YR
Volatility51.8%57.3%
Downside Capture33.58144.40
Upside Capture158.1079.74
Correlation (SPY)19.7%26.4%
TMDX Betas & Captures as of 7/31/2026

 1M2M3M6M1Y3Y
Beta-0.250.67-0.320.871.121.26
Up Beta-1.64-0.92-2.590.221.071.37
Down Beta-1.241.071.191.441.521.01
Up Capture161%157%-73%14%56%140%
Bmk +ve Days11223567138427
Stock +ve Days13253265121363
Down Capture-64%60%39%149%120%108%
Bmk -ve Days11212859114326
Stock -ve Days9183161131387

[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with TMDX
TMDX-26.0%57.2%-0.31-
Sector ETF (XLV)27.8%15.9%1.3520.6%
Equity (SPY)20.3%12.9%1.1626.8%
Gold (GLD)36.2%28.7%1.077.7%
Commodities (DBC)44.1%20.2%1.69-3.4%
Real Estate (VNQ)13.3%13.8%0.6610.8%
Bitcoin (BTCUSD)-38.8%43.2%-1.0113.2%

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Based On 5-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with TMDX
TMDX25.1%71.8%0.60-
Sector ETF (XLV)7.0%15.1%0.2827.0%
Equity (SPY)12.8%17.2%0.5737.7%
Gold (GLD)20.4%18.6%0.892.9%
Commodities (DBC)10.2%19.6%0.402.9%
Real Estate (VNQ)2.4%18.9%0.0226.3%
Bitcoin (BTCUSD)9.3%52.7%0.3618.3%

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Based On 10-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with TMDX
TMDX15.9%71.4%0.59-
Sector ETF (XLV)10.6%16.7%0.5228.0%
Equity (SPY)15.2%17.9%0.7235.7%
Gold (GLD)12.4%16.2%0.632.8%
Commodities (DBC)8.1%18.1%0.378.6%
Real Estate (VNQ)4.9%20.7%0.2028.0%
Bitcoin (BTCUSD)61.0%66.1%1.0116.5%

Smart multi-asset allocation framework can stack odds in your favor. Learn How

Short Interest

Short Interest: As Of Date7312026
Short Interest: Shares Quantity7.7 Mil
Short Interest: % Change Since 7152026-0.6%
Average Daily Volume0.8 Mil
Days-to-Cover Short Interest9.5 days
Basic Shares Quantity34.6 Mil
Short % of Basic Shares22.2%

Earnings Returns History

Updated 8/13/2026
Expand for More
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
8/4/2026-5.3%10.7% 
5/5/2026-23.2%-32.7%-24.8%
2/27/20267.9%4.1%-26.4%
10/29/20251.1%-7.3%12.0%
7/30/202510.5%10.3%8.4%
5/8/202519.6%30.7%49.6%
2/27/20255.8%-9.5%-4.9%
10/28/2024-29.9%-32.7%-36.1%
...
SUMMARY STATS   
# Positive161514
# Negative91010
Median Positive12.3%11.9%22.3%
Median Negative-9.3%-15.4%-15.4%
Max Positive51.2%53.1%96.6%
Max Negative-29.9%-32.7%-36.1%
Collapse to Preview
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
8/4/2026-5.3%10.7% 
5/5/2026-23.2%-32.7%-24.8%
2/27/20267.9%4.1%-26.4%
10/29/20251.1%-7.3%12.0%
7/30/202510.5%10.3%8.4%
5/8/202519.6%30.7%49.6%
2/27/20255.8%-9.5%-4.9%
10/28/2024-29.9%-32.7%-36.1%
7/31/20246.5%2.5%17.1%
4/30/202424.9%35.2%44.9%
2/26/202414.1%11.9%-4.2%
11/6/202351.2%48.4%84.0%
8/3/2023-8.3%-26.3%-21.0%
5/1/2023-5.2%-8.9%-6.7%
2/22/202320.5%26.0%14.4%
11/3/202224.0%24.6%37.2%
8/1/2022-10.3%10.8%23.7%
5/3/202240.3%15.1%30.3%
2/23/202230.0%53.1%96.6%
11/9/2021-9.3%-20.4%-26.8%
8/5/20218.5%7.4%16.0%
5/4/2021-11.1%-16.8%-9.8%
3/2/2021-5.6%-14.0%4.5%
11/4/20204.9%11.5%21.0%
8/5/20202.6%-2.4%-6.0%
SUMMARY STATS   
# Positive161514
# Negative91010
Median Positive12.3%11.9%22.3%
Median Negative-9.3%-15.4%-15.4%
Max Positive51.2%53.1%96.6%
Max Negative-29.9%-32.7%-36.1%

SEC Filings

Expand for More
Report DateFiling DateFiling
06/30/202608/04/202610-Q
03/31/202605/05/202610-Q
12/31/202502/24/202610-K
09/30/202510/29/202510-Q
06/30/202507/30/202510-Q
03/31/202505/08/202510-Q
12/31/202402/27/202510-K
09/30/202410/29/202410-Q
06/30/202408/01/202410-Q
03/31/202405/02/202410-Q
12/31/202302/27/202410-K
09/30/202311/08/202310-Q
06/30/202308/04/202310-Q
03/31/202305/04/202310-Q
12/31/202202/27/202310-K
09/30/202211/04/202210-Q
Collapse to Preview
Report DateFiling DateFiling
06/30/202608/04/202610-Q
03/31/202605/05/202610-Q
12/31/202502/24/202610-K
09/30/202510/29/202510-Q
06/30/202507/30/202510-Q
03/31/202505/08/202510-Q
12/31/202402/27/202510-K
09/30/202410/29/202410-Q
06/30/202408/01/202410-Q
03/31/202405/02/202410-Q
12/31/202302/27/202410-K
09/30/202311/08/202310-Q
06/30/202308/04/202310-Q
03/31/202305/04/202310-Q
12/31/202202/27/202310-K
09/30/202211/04/202210-Q
06/30/202208/03/202210-Q
03/31/202205/05/202210-Q
12/31/202103/01/202210-K
09/30/202111/09/202110-Q
06/30/202108/06/202110-Q
03/31/202105/07/202110-Q
12/31/202003/11/202110-K
09/30/202011/06/202010-Q
06/30/202008/10/202010-Q
03/31/202005/06/202010-Q
12/31/201903/17/202010-K
09/30/201911/08/201910-Q

Recent Forward Guidance

Updated 8/5/2026

Latest: Q2 2026 Earnings Reported 8/4/2026

Forward GuidanceGuidance Change
MetricLowMidHigh% Chg% DeltaChangePrior
2026 Revenue737.00 Mil747.00 Mil757.00 Mil  RaisedGuidance: 742.00 Mil for 2026
2026 Revenue Growth22.0%23.5%25.0% 1.0%RaisedGuidance: 22.5% for 2026

Prior: Q3 2025 Earnings Reported 10/29/2025

Forward GuidanceGuidance Change
MetricLowMidHigh% Chg% DeltaChangePrior
2025 Revenue595.00 Mil600.00 Mil605.00 Mil  RaisedGuidance: 595.00 Mil for 2025
2025 Revenue Growth 36.0%    

Insider Activity

Updated 7/14/2026
Expand for More
#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Gunderson, Thomas J DirectSell617202675.069,624722,3771,249,149Form
2Lovell, Stephanie DirectSell3062026149.621,193178,497428,811Form
3Weill, David DirectSell3062026146.823,571524,2941,781,514Form
4Hernandez, GerardoChief Financial OfficerDirectSell3042026147.217,2361,065,2122,162,368Form
5Hernandez, GerardoChief Financial OfficerDirectSell3042026139.1237552,1702,043,534Form
Collapse to Preview
#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Gunderson, Thomas J DirectSell617202675.069,624722,3771,249,149Form
2Lovell, Stephanie DirectSell3062026149.621,193178,497428,811Form
3Weill, David DirectSell3062026146.823,571524,2941,781,514Form
4Hernandez, GerardoChief Financial OfficerDirectSell3042026147.217,2361,065,2122,162,368Form
5Hernandez, GerardoChief Financial OfficerDirectSell3042026139.1237552,1702,043,534Form
6Ranganath, Anil PSee remarksDirectSell3042026139.12864120,2001,821,220Form
7Corcoran, NicholasSee remarksDirectSell3042026139.122,966412,6304,150,089Form
8Hernandez, GerardoChief Financial OfficerDirectSell12052025139.62920128,4502,103,236Form
9Weill, David DirectSell12052025138.645,000693,2001,682,258Form
10Ranganath, Anil PSee remarksDirectSell11262025145.223,000435,6602,026,545Form
11Hassanein, Waleed HPresident & CEOthe Waleed H. Hassanein Revocable TrustBuy11182025114.008,7751,000,35056,431,026Form
12Basile, Edward M DirectSell10312025130.454,142540,324373,870Form
13Hassanein, Waleed HPresident & CEOthe Waleed H. Hassanein Revocable TrustBuy8082025116.258,475985,20956,524,124Form
14Hassanein, Waleed HPresident & CEOthe Waleed H. Hassanein Revocable TrustBuy8082025118.688,400996,91256,700,438Form
15Basile, Edward M DirectSell8052025125.514,143519,988359,712Form

Investor Activity (13F)

Updated Aug 21, 2026
13F holdings as of Mar 31, 2026 (Q1 2026)

Active managers (13F portfolio over $250M, at least 3 holdings) with a position over $5M that is either over 10% of their portfolio or held in a concentrated book of 50 or fewer total positions. Index/ETF, sovereign, bank, community-bank and charitable/donor-advised filers are excluded.

Active ManagerValue% of PortfolioTotal PositionsQoQFiling
Opti Capital Management, LP$45.4 Mil3.3%36Hold13F
Montanaro Asset Management Ltd$7.8 Mil2.3%42New13F
Active ManagerValue% of PortfolioTotal PositionsQoQFiling
Montanaro Asset Management Ltd$7.8 Mil2.3%42New13F
Active Manager
Active ManagerValue% of PortfolioTotal PositionsQoQFiling
Opti Capital Management, LP$45.4 Mil3.3%36Hold13F
Montanaro Asset Management Ltd$7.8 Mil2.3%42New13F
Core Cache Last Updated: 8/20/2026