United Therapeutics (UTHR)


Market Price (10/31/2026): $601.98 | Market Cap: $25.8 BilSector: Health Care | Industry: Biotechnology

United Therapeutics (UTHR)


Market Price (10/31/2026): $601.98
Market Cap: $25.8 Bil
Sector: Health Care
Industry: Biotechnology

Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.

0

Attractive yield
Total YieldTotal Yield = Earnings Yield + Dividend Yield, Earnings Yield = Net Income / Market Cap Dividend Yield = Total Dividends / Market Cap is 5.1%

Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -10%

Attractive operating margins
Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is 44%

Attractive cash flow generation
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 53%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 34%

Stock buyback support
Stock Buyback 3Y Total is 3.6 Bil

Low stock price volatility
Vol 12M is 34%

Megatrend and thematic drivers
Megatrends include Biotechnology & Genomics, and Precision Medicine. Themes include Gene Editing & Therapy, Targeted Therapies, Show more.

Trading close to highs
Dist 52W High is 0.0%, Dist 3Y High is 0.0%

Weak revenue growth
Rev Chg QQuarterly Revenue Change % is -1.9%

Key risks
UTHR key risks include [1] patent expirations on its core products, Show more.

0 Attractive yield
Total YieldTotal Yield = Earnings Yield + Dividend Yield, Earnings Yield = Net Income / Market Cap Dividend Yield = Total Dividends / Market Cap is 5.1%
1 Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -10%
2 Attractive operating margins
Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is 44%
3 Attractive cash flow generation
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 53%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 34%
4 Stock buyback support
Stock Buyback 3Y Total is 3.6 Bil
5 Low stock price volatility
Vol 12M is 34%
6 Megatrend and thematic drivers
Megatrends include Biotechnology & Genomics, and Precision Medicine. Themes include Gene Editing & Therapy, Targeted Therapies, Show more.
7 Trading close to highs
Dist 52W High is 0.0%, Dist 3Y High is 0.0%
8 Weak revenue growth
Rev Chg QQuarterly Revenue Change % is -1.9%
9 Key risks
UTHR key risks include [1] patent expirations on its core products, Show more.

UTHR in ETFs

Weight = UTHR's share of each fund

VTI0.03%
ITOT0.03%
IWB0.03%
IJH0.74%
VB0.29%
QVAL2.3%
XBI1.8%
IBB1.7%
+26 more covered ETFs

Valuation & Metrics

Price Chart

Why The Stock Moved

Qualitative Assessment

AI Analysis | Feedback

Updated on 10/22/2026

United Therapeutics (UTHR) stock has gained about 10% since 6/30/2026 because of the following key factors:

1. Advancements in Key Pipeline Products' Regulatory Status.

United Therapeutics saw positive regulatory movement for its therapies, expanding potential market opportunities. The FDA accepted the supplemental New Drug Application (sNDA) for nebulized Tyvaso® (treprostinil) Inhalation Solution to treat Idiopathic Pulmonary Fibrosis (IPF) in fiscal Q3 2026 (September 2, 2026), with a decision anticipated by late April 2027. Additionally, in fiscal Q4 2026, the FDA granted clearance to proceed with the SUMMIT clinical trial of treprostinil Soft Mist Inhaler (SMI) in pulmonary hypertension associated with chronic obstructive pulmonary disease (PH-COPD) (October 19, 2026).

2. Positive Clinical Trial Data Presentations.

In fiscal Q4 2026, United Therapeutics presented new data at the CHEST 2026 Annual Meeting (October 13-21, 2026) for investigational ralinepag in pulmonary arterial hypertension (PAH) and nebulized treprostinil in IPF. A subgroup analysis from the Phase 3 ADVANCE OUTCOMES study demonstrated ralinepag reduced the risk of clinical worsening in PAH patients. A post-hoc analysis of the Phase 3 TETON-2 study showed nebulized treprostinil significantly reduced the risk of multiple disease progression events compared to placebo in IPF patients.

Show more
Updated on 10/22/2026

United Therapeutics (UTHR) stock has gained about 10% since 6/30/2026 because of the following key factors:

1. Advancements in Key Pipeline Products' Regulatory Status.

United Therapeutics saw positive regulatory movement for its therapies, expanding potential market opportunities. The FDA accepted the supplemental New Drug Application (sNDA) for nebulized Tyvaso® (treprostinil) Inhalation Solution to treat Idiopathic Pulmonary Fibrosis (IPF) in fiscal Q3 2026 (September 2, 2026), with a decision anticipated by late April 2027. Additionally, in fiscal Q4 2026, the FDA granted clearance to proceed with the SUMMIT clinical trial of treprostinil Soft Mist Inhaler (SMI) in pulmonary hypertension associated with chronic obstructive pulmonary disease (PH-COPD) (October 19, 2026).

2. Positive Clinical Trial Data Presentations.

In fiscal Q4 2026, United Therapeutics presented new data at the CHEST 2026 Annual Meeting (October 13-21, 2026) for investigational ralinepag in pulmonary arterial hypertension (PAH) and nebulized treprostinil in IPF. A subgroup analysis from the Phase 3 ADVANCE OUTCOMES study demonstrated ralinepag reduced the risk of clinical worsening in PAH patients. A post-hoc analysis of the Phase 3 TETON-2 study showed nebulized treprostinil significantly reduced the risk of multiple disease progression events compared to placebo in IPF patients.

3. Authorization of a Substantial Share Repurchase Program.

In fiscal Q4 2026 (October 22, 2026), United Therapeutics' Board of Directors authorized a new share repurchase program for up to $2 billion of its common stock, available through October 21, 2027. This action indicates management's confidence in the company's valuation and commitment to enhancing shareholder value.

4. Favorable Analyst Sentiment and Increased Price Targets.

Analyst sentiment remained broadly positive, with a consensus "Buy" rating from 12 analysts as of October 17, 2026. Several firms raised their price targets in fiscal Q4 2026; for instance, Leerink Partners increased its price target from $685.00 to $725.00 (October 19, 2026), implying a potential upside of approximately 34% from the stock's price at that time.

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Stock Movement Drivers

Fundamental Drivers

The 10.5% change in UTHR stock from 6/30/2026 to 10/30/2026 was primarily driven by a 6.3% change in the company's P/E Multiple.
(LTM values as of)630202610302026Change
Stock Price ($)541.83598.7210.5%
Change Contribution By: 
Total Revenues ($ Mil)3,1703,154-0.5%
Net Income Margin (%)40.6%41.6%2.3%
P/E Multiple18.319.56.3%
Shares Outstanding (Mil)44432.1%
Cumulative Contribution10.5%

LTM = Last Twelve Months as of date shown

Market Drivers

6/30/2026 to 10/30/2026
ReturnCorrelation
UTHR10.5% 
Market (SPY)1.2%-9.3%
Sector (XLV)16.5%5.4%

Fundamental Drivers

The 1.0% change in UTHR stock from 3/31/2026 to 10/30/2026 was primarily driven by a 1.9% change in the company's Shares Outstanding (Mil).
(LTM values as of)331202610302026Change
Stock Price ($)592.98598.721.0%
Change Contribution By: 
Total Revenues ($ Mil)3,1833,154-0.9%
Net Income Margin (%)41.9%41.6%-0.9%
P/E Multiple19.319.50.9%
Shares Outstanding (Mil)43431.9%
Cumulative Contribution1.0%

LTM = Last Twelve Months as of date shown

Market Drivers

3/31/2026 to 10/30/2026
ReturnCorrelation
UTHR1.0% 
Market (SPY)16.5%-2.5%
Sector (XLV)26.7%12.7%

Fundamental Drivers

The 42.8% change in UTHR stock from 9/30/2025 to 10/30/2026 was primarily driven by a 27.8% change in the company's P/E Multiple.
(LTM values as of)930202510302026Change
Stock Price ($)419.21598.7242.8%
Change Contribution By: 
Total Revenues ($ Mil)3,0783,1542.5%
Net Income Margin (%)40.4%41.6%3.0%
P/E Multiple15.219.527.8%
Shares Outstanding (Mil)45435.9%
Cumulative Contribution42.8%

LTM = Last Twelve Months as of date shown

Market Drivers

9/30/2025 to 10/30/2026
ReturnCorrelation
UTHR42.8% 
Market (SPY)14.4%7.8%
Sector (XLV)34.5%19.4%

Fundamental Drivers

The 165.1% change in UTHR stock from 9/30/2023 to 10/30/2026 was primarily driven by a 60.1% change in the company's P/E Multiple.
(LTM values as of)930202310302026Change
Stock Price ($)225.87598.72165.1%
Change Contribution By: 
Total Revenues ($ Mil)2,1113,15449.4%
Net Income Margin (%)41.3%41.6%0.7%
P/E Multiple12.219.560.1%
Shares Outstanding (Mil)474310.1%
Cumulative Contribution165.1%

LTM = Last Twelve Months as of date shown

Market Drivers

9/30/2023 to 10/30/2026
ReturnCorrelation
UTHR165.1% 
Market (SPY)82.9%15.0%
Sector (XLV)50.4%24.8%

Return vs. Risk

Price Returns Compared

 202120222023202420252026Total [1]
Returns
UTHR Return42%29%-21%60%38%23%294%
Peers Return35%20%8%1%58%36%276%
S&P 500 Return27%-19%24%23%16%13%106%

Monthly Win Rates [3]
UTHR Win Rate67%42%42%58%50%40% 
Peers Win Rate60%53%40%48%62%68% 
S&P 500 Win Rate75%42%67%75%67%50% 

Max Drawdowns [4]
UTHR Max Drawdown-20%-23%-26%-14%-28%-21% 
Peers Max Drawdown-19%-25%-27%-27%-23%-26% 
S&P 500 Max Drawdown-5%-25%-10%-8%-19%-9% 


[1] Cumulative total returns since the beginning of 2021
[2] Peers: JNJ, MRK, PFE, GILD, LQDA. See UTHR Returns vs. Peers.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 10/30/2026 (YTD)

How Low Can It Go

EventUTHRS&P 500
2025 US Tariff Shock
  % Loss-27.4%-18.8%
  % Gain to Breakeven37.7%23.1%
  Time to Breakeven83 days79 days
Summer-Fall 2023 Five Percent Yield Shock
  % Loss-11.1%-9.5%
  % Gain to Breakeven12.5%10.5%
  Time to Breakeven84 days24 days
2023 SVB Regional Banking Crisis
  % Loss-19.8%-6.7%
  % Gain to Breakeven24.8%7.1%
  Time to Breakeven197 days31 days
2022 Inflation Shock & Fed Tightening
  % Loss-21.1%-24.5%
  % Gain to Breakeven26.8%32.4%
  Time to Breakeven84 days427 days
2020 COVID-19 Crash
  % Loss-25.7%-33.7%
  % Gain to Breakeven34.7%50.9%
  Time to Breakeven35 days140 days
Q4 2018 Fed Policy Error / Growth Scare
  % Loss-21.2%-19.2%
  % Gain to Breakeven27.0%23.8%
  Time to Breakeven674 days105 days

Compare to JNJ, MRK, PFE, GILD, LQDA

In The Past

United Therapeutics's stock fell -27.4% during the 2025 US Tariff Shock. Such a loss loss requires a 37.7% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

EventUTHRS&P 500
2025 US Tariff Shock
  % Loss-27.4%-18.8%
  % Gain to Breakeven37.7%23.1%
  Time to Breakeven83 days79 days
2022 Inflation Shock & Fed Tightening
  % Loss-21.1%-24.5%
  % Gain to Breakeven26.8%32.4%
  Time to Breakeven84 days427 days
2020 COVID-19 Crash
  % Loss-25.7%-33.7%
  % Gain to Breakeven34.7%50.9%
  Time to Breakeven35 days140 days
Q4 2018 Fed Policy Error / Growth Scare
  % Loss-21.2%-19.2%
  % Gain to Breakeven27.0%23.8%
  Time to Breakeven674 days105 days
2015-2016 China Devaluation / Global Growth Scare
  % Loss-31.3%-12.2%
  % Gain to Breakeven45.6%13.9%
  Time to Breakeven1803 days62 days
2011 US Debt Ceiling Crisis & European Contagion
  % Loss-34.4%-17.9%
  % Gain to Breakeven52.3%21.8%
  Time to Breakeven317 days123 days
2008-2009 Global Financial Crisis
  % Loss-51.3%-53.4%
  % Gain to Breakeven105.3%114.4%
  Time to Breakeven307 days1085 days

Compare to JNJ, MRK, PFE, GILD, LQDA

In The Past

United Therapeutics's stock fell -27.4% during the 2025 US Tariff Shock. Such a loss loss requires a 37.7% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

About United Therapeutics (UTHR)

United Therapeutics Corporation (UTHR) is a biotechnology company dedicated to developing and commercializing innovative therapies for patients suffering from chronic and life-threatening diseases. The company's primary focus is on pulmonary hypertension (PH), including pulmonary arterial hypertension (PAH) and pulmonary hypertension associated with interstitial lung disease (PH-ILD), a group of severe conditions affecting the heart and lungs.

Its main commercial products are designed to improve symptoms and exercise capacity in PAH patients. These include Remodulin (an injectable prostacyclin analogue), Tyvaso (an inhaled formulation of treprostinil), Orenitram (an oral treprostinil tablet), and Adcirca (an oral PDE-5 inhibitor). United Therapeutics also offers Unituxin, a monoclonal antibody for treating high-risk neuroblastoma. These therapies address significant unmet medical needs in specialized markets.

The company maintains a robust development pipeline, actively working on new formulations and delivery systems for its existing compounds, such as Tyvaso DPI (a dry powder inhaler) and the Remunity Pump for subcutaneous treprostinil delivery. Furthermore, UTHR is exploring advanced therapies like Aurora-GT, a gene therapy aimed at rebuilding lung blood vessels, and Ralinepag for PAH. United Therapeutics serves patients globally, with a continuous commitment to expanding treatment options for severe and rare diseases.

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  • Vertex Pharmaceuticals for pulmonary hypertension.
  • An early Gilead Sciences, but for complex lung diseases like pulmonary hypertension.

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  • Remodulin: An injectable therapy used to treat pulmonary arterial hypertension (PAH) to diminish symptoms associated with exercise.
  • Tyvaso: An inhaled formulation of treprostinil that enhances exercise ability in patients with PAH and pulmonary hypertension associated with interstitial lung disease (PH-ILD).
  • Orenitram: An oral tablet dosage form of treprostinil designed to enhance exercise capacity in PAH patients.
  • Unituxin: A monoclonal antibody approved for treating high-risk neuroblastoma.
  • Adcirca: An oral PDE-5 inhibitor prescribed to enhance exercise ability in patients with PAH.
  • Tyvaso DPI: A dry powder inhalation form of Tyvaso currently under development.
  • Remunity Pump: A small, lightweight, and durable pump system being developed for the subcutaneous delivery of treprostinil.
  • RemoPro: A developing treatment targeting pulmonary arterial hypertension (PAH).
  • Ralinepag: A developing oral investigational drug for the treatment of pulmonary arterial hypertension (PAH).
  • Aurora-GT: A gene therapy product in development aimed at rebuilding blood vessels in the lungs.
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United Therapeutics (UTHR) sells primarily to individuals, specifically patients suffering from chronic and life-threatening diseases. While their products are distributed through healthcare channels such as hospitals, pharmacies, and specialty distributors, the ultimate beneficiaries and categories of customers they serve are patients.

The major categories of patients served by United Therapeutics are:

  • Patients with Pulmonary Arterial Hypertension (PAH): This is a primary focus area, with multiple therapies (Remodulin, Tyvaso, Orenitram, Adcirca, RemoPro, Ralinepag) developed for this condition.
  • Patients with other forms of Pulmonary Hypertension: This includes patients with pulmonary hypertension associated with interstitial lung disease (PH-ILD) and those with World Health Organization (WHO) Group 3 pulmonary hypertension associated with chronic obstructive pulmonary disease (PH-COPD), for whom Tyvaso is either approved or under study.
  • Patients with high-risk neuroblastoma: Unituxin is a specific therapy developed to treat this type of cancer.

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DEKA Research & Development Corp.

MannKind Corporation (MNKD)

Arena Pharmaceuticals, Inc.

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Martine Rothblatt, Founder, Chairperson, and Chief Executive Officer

Dr. Martine Rothblatt founded United Therapeutics in 1996 and has served as Chairperson and Chief Executive Officer since its inception. She was motivated to enter biotech after her daughter was diagnosed with pulmonary arterial hypertension. Previously, she created the satellite radio company SiriusXM (co-founded in 1990), serving as its Chairman and CEO. Rothblatt also served as President and CEO of GeoStar, a satellite navigation company, after graduating with law and MBA degrees from UCLA. She left Sirius in 1992 and WorldSpace (another company she created) in 1997 to become full-time Chairman and CEO of United Therapeutics. Forbes recognized Rothblatt in their "50 Over 50" and "America's Self-Made Women" lists in 2023.

James Edgemond, Chief Financial Officer and Treasurer

Mr. James Edgemond was promoted to Chief Financial Officer and Treasurer of United Therapeutics in March 2015. He joined the company in January 2013 as Treasurer and Vice President, Strategic Financial Planning. Before joining United Therapeutics, he was Vice President, Corporate Controller, and Treasurer of Clark Construction Group from 2008 through January 2013. He also held various roles at The Corporate Executive Board Company from 1998 to 2008, including Executive Director, Finance. Mr. Edgemond began his career in public accounting at KPMG Peat Marwick LLP, serving in various roles, including Senior Manager, from 1990 to 1998.

Michael Benkowitz, President and Chief Operating Officer

Mr. Michael Benkowitz joined United Therapeutics in 2011 as Executive Vice President, Organizational Development, and was promoted to President and Chief Operating Officer in 2016. In his current role, he is responsible for all commercial, medical affairs, and corporate compliance activities, most company-wide administrative functions (including human resources and information technology), many business development efforts, and several key business alliances and partnerships. Prior to United Therapeutics, his career included work as a consultant.

Paul A. Mahon, J.D., Executive Vice President, General Counsel, and Corporate Secretary

Paul A. Mahon serves as the Executive Vice President, General Counsel, and Corporate Secretary for United Therapeutics. He is a key member of the leadership team.

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The key risks to United Therapeutics' business are its significant reliance on treprostinil-based therapies, the inherent risks associated with its pipeline development and regulatory approvals, and intense competition within the pulmonary arterial hypertension (PAH) market.

  1. Reliance on Treprostinil-based Therapies and Generic Competition/Patent Expiration: United Therapeutics is heavily dependent on its treprostinil-based therapies, such as the Tyvaso franchise, which accounts for approximately 60% of the company's total revenue. The company faces significant threats from generic competition as patents on key products, including Remodulin and Tyvaso, expire. This generic competition can lead to price erosion and reduced market share, thereby weakening the company's competitive advantage. The company is also involved in litigation concerning generic competition and patent rights related to its treprostinil-based products.
  2. Pipeline Development and Regulatory Risks: A significant portion of United Therapeutics' future growth hinges on the successful development and regulatory approval of its pipeline products, such as Tyvaso DPI, Remunity Pump, RemoPro, Ralinepag, Aurora-GT, and new indications for Tyvaso. Any setbacks in clinical trials, delays in regulatory timelines for products like Ralinepag, or challenges with the xenotransplantation pipeline could significantly impact the company's future revenue and growth prospects. Furthermore, expanding into complex areas like organ manufacturing technologies presents operational risks due to untested processes.
  3. Intense Competition in the PAH Market: United Therapeutics operates in a highly competitive PAH treatment landscape, with numerous branded and generic drugs already on the market. New entrants, such as Winrevair and Yutrepia, are actively vying for market share, contributing to rising competitive pressures. This competitive environment, including various approved PAH therapies like oral ERAs, prostacyclin-class therapies, and PDE-5 inhibitors, poses a constant threat to United Therapeutics' market position and revenues.

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United Therapeutics Corporation (UTHR) operates in the biotechnology sector, focusing on therapies for chronic and life-threatening diseases, including pulmonary arterial hypertension (PAH), pulmonary hypertension associated with interstitial lung disease (PH-ILD), and neuroblastoma. The addressable markets for its main products are substantial, spanning both global and U.S. regions.

Pulmonary Arterial Hypertension (PAH) Market

United Therapeutics' products such as Remodulin, Tyvaso, Orenitram, and Adcirca address the Pulmonary Arterial Hypertension (PAH) market.

  • The global PAH market was valued at approximately USD 8.3 billion in 2024 and is projected to grow to about USD 13.9 billion by 2034.
  • In the U.S., the PAH market was valued at approximately USD 4 billion in 2024.

Pulmonary Hypertension Associated with Interstitial Lung Disease (PH-ILD) Market

Tyvaso (including Tyvaso DPI) is approved for Pulmonary Hypertension associated with Interstitial Lung Disease (PH-ILD).

  • The total market size for PH-ILD across the 7 Major Markets (7MM), which include the United States, EU4 (Germany, France, Italy, and Spain), the United Kingdom, and Japan, was approximately USD 3 billion in 2024.
  • Specifically, the PH-ILD market in the U.S. was valued at approximately USD 2 billion in 2024.

Neuroblastoma Treatment Market

Unituxin is a monoclonal antibody for treating high-risk neuroblastoma.

  • The global neuroblastoma treatment market was estimated at around USD 1.2 billion in 2024, with projections to reach approximately USD 2.1 billion by 2030.
  • North America is a leading region in the neuroblastoma market, holding over a 40% share in 2024.

Idiopathic Pulmonary Fibrosis (IPF) Market (Potential for Tyvaso)

United Therapeutics is developing Tyvaso for Idiopathic Pulmonary Fibrosis (IPF), with positive phase III results reported.

  • The U.S. IPF market is estimated to comprise more than 100,000 patients and could represent a market opportunity of over USD 4 billion if Tyvaso is approved for this indication.

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United Therapeutics Corporation (UTHR) is expected to drive future revenue growth over the next 2-3 years through several key initiatives and product advancements:

  1. Continued Growth of Tyvaso and Tyvaso DPI: The company anticipates sustained double-digit revenue growth from its Tyvaso franchise, particularly Tyvaso DPI (dry powder inhaler). This growth is attributed to increasing patient adoption in both pulmonary arterial hypertension (PAH) and pulmonary hypertension associated with interstitial lung disease (PH-ILD) markets, as well as the introduction of higher-dose cartridges for enhanced patient convenience.
  2. Launch of New Inhaled Treprostinil Products: United Therapeutics plans to file for regulatory approval of Tresmi, a soft mist inhaler, and a "super prostacyclin" in 2026, with commercial launches targeted for 2027. Tresmi aims to address and significantly reduce cough, a common side effect of dry powder inhalers. The "super prostacyclin" is designed to usher in a new era of once-a-day treatments for pulmonary hypertension.
  3. Commercialization of Ralinepag: The positive results from the ADVANCE OUTCOMES study for ralinepag, an investigational once-daily oral dosing therapy, are expected to significantly contribute to the company's PAH franchise. Analysts believe these results support approval, with ralinepag offering a projected patent life through approximately 2040 and the potential for once-daily dosing.
  4. Introduction of a New Idiopathic Pulmonary Fibrosis (IPF) Treatment: Building on the "unprecedented treatment benefit" observed in the TETON-2 study for idiopathic pulmonary fibrosis, United Therapeutics is optimistic about similar positive outcomes from its TETON-1 study. The company expects to launch a new IPF treatment by June 2027, positioning it as a major long-term revenue driver.
  5. Expansion through RemunityPRO Pump: The recent launch of the RemunityPRO pump for subcutaneous delivery of Remodulin is expected to support revenue growth. This new device offers automated priming and lower flow rates, facilitating at-home initiation of Remodulin therapy.

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Share Repurchases

  • In March 2026, United Therapeutics' Board of Directors authorized a new stock repurchase program of up to $2 billion over the next year, with an initial $1.5 billion Accelerated Share Repurchase (ASR) program executed with Citibank.
  • In March 2024, the company's Board authorized a $1 billion share repurchase program, entering into a $1 billion Accelerated Share Repurchase (ASR) agreement with Citibank.
  • In July/August 2025, a $1 billion repurchase program was authorized and subsequently implemented through Accelerated Share Repurchase agreements with Citi.

Share Issuance

  • United Therapeutics' shares outstanding increased by 2.47% in 2023, reaching 0.05 billion.
  • Shares outstanding subsequently decreased by 2.41% in 2024 to 0.049 billion.
  • In 2025, shares outstanding further declined by 1.24% to 0.048 billion.

Outbound Investments

  • In October 2023, United Therapeutics acquired Miromatrix, a company developing biologic human organs for transplantation, for $91 million.
  • Over the last five years (2020-2025), the company has made an average of 0.4 acquisitions per year.

Capital Expenditures

  • Capital expenditures were $230 million in 2023 and $247 million in 2024.
  • Expected capital expenditures are $246.5 million for 2025 and $120 million for 2026.
  • Significant capital investments have been directed towards supporting a new Tyvaso DPI manufacturing facility in North Carolina and acquiring additional real estate for future commercial manufacturing needs.

Better Bets vs. United Therapeutics (UTHR)

Peer Outperformance in Biotechnology

UTHR has outperformed 93% of its 361 Biotechnology peers over 5Y. Biotechnology ranks 9th of 10 industries in Health Care by median 5Y return. The sector’s gains have largely come from elsewhere.
Share of Biotechnology constituents that UTHR has outperformed, by holding period. Peers without a full price history over a given window are excluded from that window.
1Y
77%
of 450 industry peers · 32.0% return
3Y
82%
of 396 industry peers · 168.7% return
5Y
93%
of 361 industry peers · 213.9% return
No Biotechnology peer with a comparable growth profile has beaten UTHR by more than 20pp over 5Y.
Median price return by industry across the Health Care sector, ranked by 5Y. Biotechnology is UTHR's own industry. Use this to see which corners of the sector have carried the returns.
Industry Names 1Y med3Y med5Y med Top 3 by 5Y
Health Care Distributors 6 9.3%56.9%98.5% CAH 480% · MCK 390% · COR 186%
Health Care Services 20 37.1%44.9%12.4% HIMS 255% · RDNT 136% · DGX 89%
Managed Health Care 8 34.3%-1.3%-3.6% OSCR 76% · HQY 55% · ELV 4%
Health Care Facilities 25 12.3%15.9%-5.4% THC 281% · NHC 236% · EHC 182%
Health Care Equipment 50 -0.4%12.2%-17.8% GKOS 420% · UFPT 360% · PLSE 148%
Pharmaceuticals 61 -13.5%9.4%-34.9% LQDA 1102% · KNSA 788% · LLY 482%
Health Care Supplies 11 16.7%1.0%-39.9% LNTH 329% · HAE 74% · MMSI 28%
Life Sciences Tools & Services 107 -5.3%-0.6%-66.4% NTRA 262% · AXGN 225% · MEDP 188%
Biotechnology ← 362 -24.8%-26.7%-80.9% DNTH 1187% · ELVN 1129% · TRVI 1054%
Health Care Technology 21 -24.4%-48.5%-82.4% VEEV -1% · DOCS -53%
Median of constituents with a full price history over each window. Top names are limited to companies above $2B market cap.

Latest Trefis Analyses

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Financials

UTHRJNJMRKPFEGILDLQDAMedian
NameUnited T.Johnson .Merck Pfizer Gilead S.Liquidia  
Mkt Price601.98273.74149.4730.46170.6445.33160.06
Mkt Cap25.6659.6369.2173.6211.94.0192.8
Rev LTM3,15499,33566,56963,69530,98745147,341
Op Inc LTM1,40325,5256,98517,01911,6991699,342
FCF LTM1,08819,59516,06310,98513,78014812,382
FCF 3Y Avg1,01219,10014,6449,41110,791-2110,101
CFO LTM1,68526,15919,96713,40114,47916813,940
CFO 3Y Avg1,38725,17018,39712,19811,389-811,794

Growth & Margins

UTHRJNJMRKPFEGILDLQDAMedian
NameUnited T.Johnson .Merck Pfizer Gilead S.Liquidia  
Rev Chg LTM2.5%7.8%4.6%-0.2%6.5%2,233.6%5.6%
Rev Chg 3Y Avg14.7%5.9%4.5%-5.2%4.2%749.1%5.2%
Rev Chg Q-1.9%5.9%5.1%2.6%6.8%1,842.7%5.5%
QoQ Delta Rev Chg LTM-0.5%1.4%1.2%0.6%1.7%56.5%1.3%
Op Inc Chg LTM-8.9%7.9%-64.8%2.1%4.1%222.0%3.1%
Op Inc Chg 3Y Avg9.7%4.4%36.7%233.9%0.0%24.8%17.3%
Op Mgn LTM44.5%25.7%10.5%26.7%37.8%37.4%32.1%
Op Mgn 3Y Avg47.6%25.4%22.4%18.7%37.4%-444.6%23.9%
QoQ Delta Op Mgn LTM-1.5%-1.1%-9.2%-0.5%-0.7%21.6%-0.9%
CFO/Rev LTM53.4%26.3%30.0%21.0%46.7%37.2%33.6%
CFO/Rev 3Y Avg46.7%27.1%28.6%19.7%38.5%-356.4%27.9%
FCF/Rev LTM34.5%19.7%24.1%17.2%44.5%32.8%28.4%
FCF/Rev 3Y Avg34.3%20.6%22.8%15.1%36.4%-399.9%21.7%

Valuation

UTHRJNJMRKPFEGILDLQDAMedian
NameUnited T.Johnson .Merck Pfizer Gilead S.Liquidia  
Mkt Cap25.6659.6369.2173.6211.94.0192.8
P/S8.16.65.52.76.88.96.7
P/Op Inc18.325.852.910.218.123.921.1
P/EBIT16.235.248.025.1-139.222.924.0
P/E19.641.0116.440.1-54.929.134.6
P/CFO15.225.218.513.014.624.016.9
Total Yield5.1%4.4%3.1%8.1%0.1%3.5%3.9%
Dividend Yield0.0%1.9%2.2%5.6%1.9%0.0%1.9%
FCF Yield 3Y Avg6.4%4.0%5.6%6.7%7.7%-6.4%6.0%
D/E0.00.10.10.40.10.00.1
Net D/E-0.10.00.10.30.1-0.00.1

Returns

UTHRJNJMRKPFEGILDLQDAMedian
NameUnited T.Johnson .Merck Pfizer Gilead S.Liquidia  
1M Rtn11.1%3.4%2.9%6.8%14.5%49.8%8.9%
3M Rtn16.3%7.3%15.5%21.8%31.8%-46.1%15.9%
6M Rtn5.5%21.8%35.0%19.7%31.2%18.9%20.7%
12M Rtn32.7%48.1%78.3%34.2%47.6%95.4%47.8%
3Y Rtn170.1%101.0%59.5%20.9%138.8%596.3%119.9%
1M Excs Rtn4.3%4.8%2.9%7.3%14.7%60.9%6.1%
3M Excs Rtn14.7%6.2%15.8%19.8%29.0%-47.8%15.2%
6M Excs Rtn-1.6%14.7%27.9%12.6%24.1%11.7%13.6%
12M Excs Rtn19.8%37.6%65.3%21.8%35.2%89.5%36.4%
3Y Excs Rtn82.7%11.5%-26.9%-64.6%54.3%537.5%32.9%

FDA Approved Drugs Data

Expand for More
Post-Approval Fwd Returns
FDA
App #
Brand
Name
Generic
Name
Dosage
Form
FDA
Approval
3M
Rtn
6M
Rtn
1Y
Rtn
2Y
Rtn
Total
Rtn
NDA214324  TYVASO DPItreprostinilpowder52320224.8%26.4%2.9%31.6%184.9%
NDA208276  REMODULINtreprostinilsolution7302018-2.2%-3.3%-33.9%-6.3%397.9%
BLA125516  UNITUXINdinutuximabinjectable31020158.7%-5.9%-24.3%-10.6%265.4%
NDA203496  ORENITRAMtreprostinil diolaminetablet, extended release122020137.9%-0.4%52.0%76.7%581.6%
NDA022387  TYVASOtreprostinilsolution730200936.2%85.4%53.4%80.1%1,779.0%
Collapse to Preview
Post-Approval Fwd Returns
FDA
App #
Brand
Name
Generic
Name
Dosage
Form
FDA
Approval
3M
Rtn
6M
Rtn
1Y
Rtn
2Y
Rtn
Total
Rtn
NDA214324  TYVASO DPItreprostinilpowder52320224.8%26.4%2.9%31.6%184.9%
NDA208276  REMODULINtreprostinilsolution7302018-2.2%-3.3%-33.9%-6.3%397.9%
BLA125516  UNITUXINdinutuximabinjectable31020158.7%-5.9%-24.3%-10.6%265.4%
NDA203496  ORENITRAMtreprostinil diolaminetablet, extended release122020137.9%-0.4%52.0%76.7%581.6%
NDA022387  TYVASOtreprostinilsolution730200936.2%85.4%53.4%80.1%1,779.0%

Clinical Pipeline

Drug CandidateIndicationPhase 3 TrialsEst. Primary Completion
RalinepagPulmonary Arterial Hypertension1Dec 2026
Inhaled TreprostinilProgressive Pulmonary Fibrosis2Nov 2027
Active Phase 3 studies led by the company. Source: ClinicalTrials.gov · Updated 8/28/2026

Financials

Segment Financials

Revenue by Segment
$ Mil20252024202320222021
Tyvaso DPI1,2921,0347311580
Nebulized Tyvaso586587503715608
Remodulin527538495500514
Orenitram497434359325306
Unituxin227239199183202
Adcirca3024294156
Other242212140
Total3,1832,8772,3281,9361,686


Operating Income by Segment
$ Mil2005
Pharmaceutical66
Telemedicine-1
Total65


Assets by Segment
$ Mil20102009200820072006
PHARMACEUTICAL1,4091,031   
TELEMEDICINE2320   
Pharmaceutical  854555466
Telemedicine  183212
Total1,4321,052871587479


Price Behavior

Price Behavior
Market Price$598.72 
Market Cap ($ Bil)25.5 
First Trading Date06/17/1999 
Distance from 52W High0.0% 
   50 Days200 Days
DMA Price$527.10$531.54
DMA Trendupup
Distance from DMA13.6%12.6%
 3M1YR
Volatility38.3%34.2%
Downside Capture-53.270.20
Upside Capture25.8830.56
Correlation (S&P 500)-7.9%7.9%
UTHR Betas & Captures as of 9/30/2026

 1M2M3M6M1Y3Y
Beta-0.81-0.37-0.33-0.030.240.38
Up Beta1.810.020.140.710.350.40
Down Beta0.72-0.20-0.16-0.050.240.54
Up Capture-97%-29%-41%-25%24%16%
Bmk +ve Days6162766132424
Stock +ve Days8172655121389
Down Capture-182%-93%-60%-27%7%31%
Bmk -ve Days16263760120328
Stock -ve Days14253871131362

[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with UTHR
UTHR31.6%34.2%0.84-
Sector ETF (XLV)30.2%16.4%1.4119.9%
Equity (SPY)10.9%12.8%0.527.9%
Gold (GLD)-2.0%28.6%-0.082.1%
Commodities (DBC)48.2%20.6%1.79-5.3%
Real Estate (VNQ)10.2%13.7%0.458.8%
Bitcoin (BTCUSD)-30.3%43.5%-0.7110.4%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 5-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with UTHR
UTHR26.1%35.1%0.72-
Sector ETF (XLV)8.7%15.3%0.3729.2%
Equity (SPY)12.2%17.1%0.5319.0%
Gold (GLD)16.2%19.0%0.685.3%
Commodities (DBC)9.2%19.5%0.355.8%
Real Estate (VNQ)0.9%18.9%-0.0617.1%
Bitcoin (BTCUSD)4.8%51.6%0.289.2%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 10-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with UTHR
UTHR18.3%35.1%0.57-
Sector ETF (XLV)12.0%16.8%0.5937.1%
Equity (SPY)15.2%17.9%0.7230.8%
Gold (GLD)11.4%16.5%0.563.3%
Commodities (DBC)8.2%18.1%0.3712.3%
Real Estate (VNQ)5.3%20.7%0.2124.6%
Bitcoin (BTCUSD)61.7%66.2%1.0110.6%

Smart multi-asset allocation framework can stack odds in your favor. Learn How

Short Interest

Short Interest: As Of Date10152026
Short Interest: Shares Quantity2.5 Mil
Short Interest: % Change Since 9302026-31.7%
Average Daily Volume1.0 Mil
Days-to-Cover Short Interest2.6 days
Basic Shares Quantity42.6 Mil
Short % of Basic Shares5.8%

Earnings Returns History

Updated 10/14/2026
Expand for More
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
8/5/20260.1%-0.6%-5.1%
5/6/20264.3%1.7%-4.3%
2/25/2026-5.9%-8.4%-0.5%
10/29/20259.6%5.3%17.6%
7/30/2025-5.2%2.4%2.6%
4/30/20250.8%-1.9%6.5%
2/26/20251.5%-2.5%-3.4%
10/30/20242.4%8.5%7.2%
...
SUMMARY STATS   
# Positive181314
# Negative61110
Median Positive2.2%4.3%7.9%
Median Negative-4.9%-2.5%-4.6%
Max Positive14.1%15.1%27.0%
Max Negative-7.2%-8.4%-11.4%
Collapse to Preview
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
8/5/20260.1%-0.6%-5.1%
5/6/20264.3%1.7%-4.3%
2/25/2026-5.9%-8.4%-0.5%
10/29/20259.6%5.3%17.6%
7/30/2025-5.2%2.4%2.6%
4/30/20250.8%-1.9%6.5%
2/26/20251.5%-2.5%-3.4%
10/30/20242.4%8.5%7.2%
7/31/2024-7.2%-4.6%6.6%
5/1/20248.9%13.6%15.4%
2/21/2024-0.7%3.7%8.1%
11/1/20230.5%3.4%7.7%
8/2/20230.3%-1.4%-4.9%
5/3/2023-4.5%-8.4%-6.7%
2/22/20231.9%0.5%-11.4%
11/2/202211.1%15.1%20.7%
8/3/20221.7%-2.5%0.8%
5/4/20223.7%-0.3%27.0%
2/24/20220.2%4.3%4.3%
11/3/20215.7%3.5%-1.5%
8/4/202114.1%13.1%17.8%
5/5/20211.4%-0.5%-10.3%
2/24/2021-2.8%-6.0%-3.1%
10/28/20207.0%10.6%9.5%
SUMMARY STATS   
# Positive181314
# Negative61110
Median Positive2.2%4.3%7.9%
Median Negative-4.9%-2.5%-4.6%
Max Positive14.1%15.1%27.0%
Max Negative-7.2%-8.4%-11.4%

SEC Filings

Expand for More
Report DateFiling DateFiling
06/30/202608/05/202610-Q
03/31/202605/06/202610-Q
12/31/202502/25/202610-K
09/30/202510/29/202510-Q
06/30/202507/30/202510-Q
03/31/202504/30/202510-Q
12/31/202402/26/202510-K
09/30/202410/30/202410-Q
06/30/202407/31/202410-Q
03/31/202405/01/202410-Q
12/31/202302/21/202410-K
09/30/202311/01/202310-Q
06/30/202308/02/202310-Q
03/31/202305/03/202310-Q
12/31/202202/22/202310-K
09/30/202211/02/202210-Q
Collapse to Preview
Report DateFiling DateFiling
06/30/202608/05/202610-Q
03/31/202605/06/202610-Q
12/31/202502/25/202610-K
09/30/202510/29/202510-Q
06/30/202507/30/202510-Q
03/31/202504/30/202510-Q
12/31/202402/26/202510-K
09/30/202410/30/202410-Q
06/30/202407/31/202410-Q
03/31/202405/01/202410-Q
12/31/202302/21/202410-K
09/30/202311/01/202310-Q
06/30/202308/02/202310-Q
03/31/202305/03/202310-Q
12/31/202202/22/202310-K
09/30/202211/02/202210-Q
06/30/202208/03/202210-Q
03/31/202205/04/202210-Q
12/31/202102/24/202210-K
09/30/202111/03/202110-Q
06/30/202108/04/202110-Q
03/31/202105/05/202110-Q
12/31/202002/24/202110-K
09/30/202010/28/202010-Q
06/30/202007/29/202010-Q
03/31/202004/29/202010-Q
12/31/201902/26/202010-K
09/30/201910/30/201910-Q

Insider Activity

Updated 10/30/2026
Expand for More
#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Rothblatt, Martine AChairperson & CEOby TrustSell10302026594.789,5005,650,415192,972,361Form
2Rothblatt, Martine AChairperson & CEOby TrustSell10292026585.499,5005,562,190189,959,329Form
3Rothblatt, Martine AChairperson & CEOby TrustSell10282026587.739,5005,583,418190,684,315Form
4Rothblatt, Martine AChairperson & CEOby TrustSell10272026588.649,5005,592,095190,980,628Form
5Rothblatt, Martine AChairperson & CEOby TrustSell10262026582.769,5005,536,235189,072,916Form
Collapse to Preview
#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Rothblatt, Martine AChairperson & CEOby TrustSell10302026594.789,5005,650,415192,972,361Form
2Rothblatt, Martine AChairperson & CEOby TrustSell10292026585.499,5005,562,190189,959,329Form
3Rothblatt, Martine AChairperson & CEOby TrustSell10282026587.739,5005,583,418190,684,315Form
4Rothblatt, Martine AChairperson & CEOby TrustSell10272026588.649,5005,592,095190,980,628Form
5Rothblatt, Martine AChairperson & CEOby TrustSell10262026582.769,5005,536,235189,072,916Form
6Rothblatt, Martine AChairperson & CEOby TrustSell10232026583.389,5005,542,094189,273,000Form
7Rothblatt, Martine AChairperson & CEOby TrustSell10222026560.079,5005,320,681181,711,329Form
8Rothblatt, Martine AChairperson & CEOby TrustSell10212026553.879,5005,261,741179,698,412Form
9Rothblatt, Martine AChairperson & CEOby TrustSell10202026543.329,5005,161,576176,277,592Form
10Rothblatt, Martine AChairperson & CEOby TrustSell10192026534.669,5005,079,275173,466,860Form
11Rothblatt, Martine AChairperson & CEOby TrustSell10162026546.659,5005,193,200177,357,610Form
12Mahon, Paul AEVP & GENERAL COUNSELDirectSell10152026544.308,3004,517,70924,587,223Form
13Rothblatt, Martine AChairperson & CEOby TrustSell10152026539.999,5005,129,873175,194,883Form
14Rothblatt, Martine AChairperson & CEOby TrustSell10142026545.529,5005,182,414176,989,264Form
15Rothblatt, Martine AChairperson & CEOby TrustSell10132026550.709,5005,231,666178,671,321Form
16Rothblatt, Martine AChairperson & CEOby TrustSell10132026544.949,5005,176,936176,802,169Form
17Rothblatt, Martine AChairperson & CEOby TrustSell10092026534.319,5005,075,919173,352,246Form
18Rothblatt, Martine AChairperson & CEOby TrustSell10082026548.959,5005,215,015178,102,648Form
19Rothblatt, Martine AChairperson & CEOby TrustSell10072026538.679,5005,117,412174,769,313Form
20Rothblatt, Martine AChairperson & CEOby TrustSell10062026541.649,5005,145,537175,729,840Form
21Rothblatt, Martine AChairperson & CEOby TrustSell10052026549.379,5005,219,015178,239,243Form
22Rothblatt, Martine AChairperson & CEOby TrustSell10022026576.479,5005,476,462187,031,569Form
23Mahon, Paul AEVP & GENERAL COUNSELDirectSell10012026564.958,3004,689,05125,519,734Form
24Rothblatt, Martine AChairperson & CEOby TrustSell10012026550.221,9201,056,425178,515,483Form
25Rothblatt, Martine AChairperson & CEOby TrustSell10012026517.977,5803,926,177169,044,715Form
26Rothblatt, Martine AChairperson & CEOby TrustSell9302026477.429,5004,535,480154,895,232Form
27Rothblatt, Martine AChairperson & CEOby TrustSell9292026480.859,5004,568,106156,009,484Form
28Rothblatt, Martine AChairperson & CEOby TrustSell9282026476.179,5004,523,635154,490,712Form
29Rothblatt, Martine AChairperson & CEOby TrustSell9252026473.559,5004,498,753153,640,926Form
30Rothblatt, Martine AChairperson & CEOby TrustSell9242026491.579,5004,669,918159,486,532Form
31Rothblatt, Martine AChairperson & CEOby TrustSell9232026494.839,5004,700,851160,542,954Form
32Rothblatt, Martine AChairperson & CEOby TrustSell9222026494.559,5004,698,271160,454,848Form
33Rothblatt, Martine AChairperson & CEOby TrustSell9212026494.799,5004,700,505160,531,141Form
34Mahon, Paul AEVP & GENERAL COUNSELDirectSell9182026497.548,3004,129,60822,475,018Form
35Rothblatt, Martine AChairperson & CEOby TrustSell9182026496.069,5004,712,580160,943,552Form
36Rothblatt, Martine AChairperson & CEOby TrustSell9172026501.399,5004,763,172162,671,355Form
37Rothblatt, Martine AChairperson & CEOby TrustSell9162026501.599,5004,765,119162,737,852Form
38Mesa, NildaDirectSell9152026505.87228115,3382,822,742Form
39Rothblatt, Martine AChairperson & CEOby TrustSell9152026504.129,5004,789,152163,558,614Form
40Rothblatt, Martine AChairperson & CEOby TrustSell9142026500.829,5004,757,773162,486,976Form
41Rothblatt, Martine AChairperson & CEOby TrustSell9112026502.359,5004,772,295162,982,923Form
42Rothblatt, Martine AChairperson & CEOby TrustSell9102026501.849,5004,767,467162,818,038Form
43Rothblatt, Martine AChairperson & CEOby TrustSell9092026499.039,5004,740,795161,907,145Form
44Rothblatt, Martine AChairperson & CEOby TrustSell9082026489.209,5004,647,354158,715,959Form
45Rothblatt, Martine AChairperson & CEOby TrustSell9042026487.549,5004,631,619158,178,579Form
46Mahon, Paul AEVP & GENERAL COUNSELDirectSell9032026482.038,3004,000,83621,774,190Form
47Rothblatt, Martine AChairperson & CEOby TrustSell9032026493.469,5004,687,841160,098,663Form
48Rothblatt, Martine AChairperson & CEOby TrustSell9022026514.099,5004,883,839166,792,367Form
49Rothblatt, Martine AChairperson & CEOby TrustSell9012026511.099,5004,855,312165,818,118Form
50Rothblatt, Martine AChairperson & CEOby TrustSell8312026517.519,5004,916,363167,903,124Form
51Rothblatt, Martine AChairperson & CEOby TrustSell8282026522.579,5004,964,376169,542,835Form
52Rothblatt, Martine AChairperson & CEOby TrustSell8272026517.289,5004,914,190167,828,886Form
53Rothblatt, Martine AChairperson & CEOby TrustSell8262026517.719,5004,918,273167,968,348Form
54Rothblatt, Martine AChairperson & CEOby TrustSell8252026511.979,5004,863,730166,105,599Form
55Rothblatt, Martine AChairperson & CEOby TrustSell8242026518.399,5004,924,666168,186,670Form
56Rothblatt, Martine AChairperson & CEOby TrustSell8202026526.969,5005,006,104170,967,928Form
57Rothblatt, Martine AChairperson & CEOby TrustSell8192026515.609,5004,898,221167,283,528Form
58Rothblatt, Martine AChairperson & CEOby TrustSell8182026506.599,5004,812,568164,358,327Form
59Rothblatt, Martine AChairperson & CEOby TrustSell8172026498.919,5004,739,664161,868,516Form
60Rothblatt, Martine AChairperson & CEOby TrustSell8142026504.249,5004,790,316163,598,381Form
61Rothblatt, Martine AChairperson & CEOby TrustSell8132026515.039,5004,892,748167,096,619Form
62Rothblatt, Martine AChairperson & CEOby TrustSell8122026522.879,5004,967,292169,642,433Form
63Rothblatt, Martine AChairperson & CEOby TrustSell8112026530.119,5005,036,073171,991,437Form
64Rothblatt, Martine AChairperson & CEOby TrustSell8102026531.389,5005,048,137172,403,446Form
65Rothblatt, Martine AChairperson & CEOby TrustSell8072026525.369,5004,990,873170,447,784Form
66Mahon, Paul AEVP & GENERAL COUNSELDirectSell8062026517.058,3004,291,51223,356,169Form
67Rothblatt, Martine AChairperson & CEOby TrustSell8062026518.749,5004,927,985168,300,027Form
68Rothblatt, Martine AChairperson & CEOby TrustSell8052026517.099,5004,912,310167,764,697Form
69Rothblatt, Martine AChairperson & CEOby TrustSell8042026516.069,5004,902,569167,432,029Form
70Rothblatt, Martine AChairperson & CEOby TrustSell8032026518.969,5004,930,098168,372,184Form
71Rothblatt, Martine AChairperson & CEOby TrustSell7302026522.379,5004,962,488169,478,360Form
72Rothblatt, Martine AChairperson & CEOby TrustSell7282026526.739,5005,003,976170,895,246Form
73Rothblatt, Martine AChairperson & CEOby TrustSell7272026530.429,5005,038,971172,090,399Form
74Rothblatt, Martine AChairperson & CEOby TrustSell7272026531.749,5005,051,519172,518,929Form
75Rothblatt, Martine AChairperson & CEOby TrustSell7242026528.589,5005,021,520171,494,406Form
76Rothblatt, Martine AChairperson & CEOby TrustSell7232026530.579,5005,040,380172,138,525Form
77Rothblatt, Martine AChairperson & CEOby TrustSell7222026532.249,5005,056,298172,682,164Form
78Rothblatt, Martine AChairperson & CEOby TrustSell7212026531.699,5005,051,035172,502,403Form
79Rothblatt, Martine AChairperson & CEOby TrustSell7202026537.059,5005,101,939174,240,899Form
80Rothblatt, Martine AChairperson & CEOby TrustSell7172026530.919,5005,043,689172,251,528Form
81Mahon, Paul AEVP & GENERAL COUNSELDirectSell7162026533.698,3004,429,63824,107,904Form
82Rothblatt, Martine AChairperson & CEODirectSell7162026530.411,718911,25321,488,701Form
83Rothblatt, Martine AChairperson & CEOby TrustSell7162026530.347,7824,127,087172,064,308Form
84Rothblatt, Martine AChairperson & CEODirectSell7152026526.839,5005,004,90921,343,565Form
85Rothblatt, Martine AChairperson & CEODirectSell7142026535.999,5005,091,94921,714,752Form
86Rothblatt, Martine AChairperson & CEODirectSell7132026544.609,5005,173,66022,063,208Form
87Malcolm, JanDirectSell7102026550.59325178,942247,766Form
88Rothblatt, Martine AChairperson & CEODirectSell7092026551.139,5005,235,75622,328,020Form
89Rothblatt, Martine AChairperson & CEODirectSell7092026553.179,5005,255,11122,410,561Form
90Rothblatt, Martine AChairperson & CEODirectSell7082026558.879,5005,309,29622,641,632Form
91Rothblatt, Martine AChairperson & CEODirectSell7072026548.969,5005,215,13322,240,074Form
92Rothblatt, Martine AChairperson & CEODirectSell7012026541.009,5005,139,54221,917,711Form
93Rothblatt, Martine AChairperson & CEODirectSell6302026545.809,5005,185,13322,112,136Form
94Rothblatt, Martine AChairperson & CEODirectSell6292026543.979,5005,167,73422,037,939Form
95Rothblatt, Martine AChairperson & CEODirectSell6262026550.409,5005,228,77322,298,238Form
96Rothblatt, Martine AChairperson & CEODirectSell6252026548.699,5005,212,52022,228,928Form
97Edgemond, JamesCFO AND TREASURERDirectSell6232026538.158,7504,708,78610,158,061Form
98Rothblatt, Martine AChairperson & CEODirectSell6232026537.749,5005,108,52721,785,448Form
99Edgemond, JamesCFO AND TREASURERDirectSell6222026540.1510,0005,401,48810,195,850Form
100Rothblatt, Martine AChairperson & CEODirectSell6222026540.189,5005,131,71121,884,316Form
101Rothblatt, Martine AChairperson & CEODirectSell6172026549.809,5005,223,06822,273,913Form
102Rothblatt, Martine AChairperson & CEODirectSell6162026549.159,5005,216,91822,247,683Form
103Edgemond, JamesCFO AND TREASURERDirectSell6162026549.1710,0005,491,74210,366,212Form
104Rothblatt, Martine AChairperson & CEODirectSell6152026541.399,5005,143,21421,933,372Form
105Edgemond, JamesCFO AND TREASURERDirectSell6122026549.2910,0005,492,89410,368,386Form
106Rothblatt, Martine AChairperson & CEODirectSell6122026549.239,5005,217,68422,250,953Form
107Rothblatt, Martine AChairperson & CEODirectSell6112026545.839,5005,185,36522,113,126Form
108Rothblatt, Martine AChairperson & CEODirectSell6102026549.329,5005,218,53422,254,575Form
109Edgemond, JamesCFO AND TREASURERDirectSell6092026547.5010,0005,475,04510,334,695Form
110Rothblatt, Martine AChairperson & CEODirectSell6092026547.499,5005,201,11022,180,269Form
111Rothblatt, Martine AChairperson & CEODirectSell6082026547.629,5005,202,43622,185,927Form
112Edgemond, JamesCFO AND TREASURERDirectSell6052026546.2810,0005,462,82410,311,627Form
113Rothblatt, Martine AChairperson & CEODirectSell6052026546.339,5005,190,12822,133,435Form
114Mahon, Paul AEVP & GENERAL COUNSELDirectSell6042026547.078,3004,540,64224,712,036Form
115Rothblatt, Martine AChairperson & CEODirectSell6042026547.619,5005,202,27122,185,221Form
116Rothblatt, Martine AChairperson & CEODirectSell6032026538.399,5005,114,74221,811,950Form
117Rothblatt, Martine AChairperson & CEODirectSell6022026547.919,5005,205,10522,197,306Form
118Edgemond, JamesCFO AND TREASURERDirectSell6022026547.8710,0005,478,66310,341,525Form
119Rothblatt, Martine AChairperson & CEODirectSell6012026553.839,5005,261,36522,437,231Form
120Edgemond, JamesCFO AND TREASURERDirectSell5292026565.6310,0005,656,29810,676,829Form
121Rothblatt, Martine AChairperson & CEODirectSell5292026565.649,5005,373,59222,915,826Form
122Rothblatt, Martine AChairperson & CEODirectSell5282026575.409,5005,466,28323,311,109Form
123Rothblatt, Martine AChairperson & CEODirectSell5262026567.749,5005,393,55823,000,971Form
124Edgemond, JamesCFO AND TREASURERDirectSell5222026564.1110,0005,641,13010,648,197Form
125Rothblatt, Martine AChairperson & CEODirectSell5222026564.119,5005,359,01122,853,645Form
126Rothblatt, Martine AChairperson & CEODirectSell5202026567.949,5005,395,39923,008,820Form
127Rothblatt, Martine AChairperson & CEODirectSell5182026568.119,5005,397,07723,015,977Form
128Edgemond, JamesCFO AND TREASURERDirectSell5152026574.4710,0005,744,74610,843,782Form
129Rothblatt, Martine AChairperson & CEODirectSell5152026574.489,5005,457,56623,273,933Form
130Mesa, NildaDirectSell5132026581.93258150,1392,925,969Form
131Rothblatt, Martine AChairperson & CEODirectSell5132026578.389,5005,494,56323,431,708Form
132Rothblatt, Martine AChairperson & CEODirectSell5112026564.959,5005,367,04422,887,899Form
133Edgemond, JamesCFO AND TREASURERDirectSell5112026578.5810,0005,785,77510,921,229Form
134Rothblatt, Martine AChairperson & CEODirectSell5112026578.549,5005,496,08423,438,196Form
135Rothblatt, Martine AChairperson & CEODirectSell5062026576.249,5005,474,24023,345,041Form
136Rothblatt, Martine AChairperson & CEODirectSell5042026570.589,5005,420,47223,115,744Form
137Edgemond, JamesCFO AND TREASURERDirectSell5012026572.6110,0005,726,06210,808,514Form
138Rothblatt, Martine AChairperson & CEODirectSell5012026572.639,5005,439,99123,198,984Form
139Rothblatt, Martine AChairperson & CEODirectSell4302026571.229,5005,426,59823,141,869Form
140Edgemond, JamesCFO AND TREASURERDirectSell4282026568.8310,0005,688,31910,737,271Form
141Rothblatt, Martine AChairperson & CEODirectSell4282026568.819,5005,403,68423,044,154Form
142Rothblatt, Martine AChairperson & CEODirectSell4272026564.819,5005,365,67822,882,074Form
143Patusky, ChristopherDirectSell4242026569.002,9101,655,790847,810Form
144Edgemond, JamesCFO AND TREASURERDirectSell4242026572.219,6365,513,83010,801,065Form
145Rothblatt, Martine AChairperson & CEODirectSell4242026572.359,5005,437,34023,187,677Form
146Edgemond, JamesCFO AND TREASURERDirectSell4242026575.85364209,60810,938,754Form
147Rothblatt, Martine AChairperson & CEODirectSell4222026570.429,5005,419,00623,109,495Form
148Rothblatt, Martine AChairperson & CEODirectSell4202026586.669,5005,573,22323,767,157Form
149Mahon, Paul AEVP & GENERAL COUNSELDirectSell4162026576.828,3004,787,59726,056,062Form
150Rothblatt, Martine AChairperson & CEODirectSell4162026580.369,5005,513,40123,512,042Form
151Rothblatt, Martine AChairperson & CEODirectSell4162026579.369,5005,503,94923,471,736Form
152Rothblatt, Martine AChairperson & CEOby TrustSell4162026536.957540,271174,209,669Form
153Rothblatt, Martine AChairperson & CEODirectSell4132026569.289,5005,408,19423,063,386Form
154Edgemond, JamesCFO AND TREASURERDirectSell4102026577.8910,0005,778,92210,908,292Form
155Rothblatt, Martine AChairperson & CEODirectSell4102026577.889,5005,489,81923,411,479Form
156Rothblatt, Martine AChairperson & CEODirectSell4082026564.019,5005,358,11622,849,826Form
157Edgemond, JamesCFO AND TREASURERDirectSell4062026561.5010,0005,614,98410,598,844Form
158Rothblatt, Martine AChairperson & CEODirectSell4062026561.379,5005,333,05322,742,944Form
159Mahon, Paul AEVP & GENERAL COUNSELDirectSell4022026565.878,3004,696,69025,561,312Form
160Rothblatt, Martine AChairperson & CEODirectSell4022026581.639,5005,525,52623,563,751Form
161Rothblatt, Martine AChairperson & CEODirectSell4022026585.769,5005,564,70923,730,848Form
162Rothblatt, Martine AChairperson & CEODirectSell3312026590.599,5005,610,56423,926,399Form
163Edgemond, JamesCFO AND TREASURERDirectSell3312026593.1710,0005,931,68311,196,645Form
164Causey, ChristopherDirectSell3302026604.641,300786,0322,533,442Form
165Rothblatt, Martine AChairperson & CEODirectSell3302026526.969,5005,006,10021,348,643Form
166Edgemond, JamesCFO AND TREASURERDirectSell3272026535.9010,0005,359,00510,115,658Form
167Rothblatt, Martine AChairperson & CEODirectSell3272026535.819,5005,090,21621,707,360Form
168Rothblatt, Martine AChairperson & CEODirectSell3252026529.369,5005,028,91921,445,958Form
169Rothblatt, Martine AChairperson & CEODirectSell3232026524.999,5004,987,38721,268,842Form
170Rothblatt, Martine AChairperson & CEODirectSell3202026528.839,5005,023,88421,424,487Form
171Rothblatt, Martine AChairperson & CEODirectSell3182026536.759,5005,099,10421,745,262Form
172Malcolm, JanDirectSell3172026533.514524,00866,689Form
173Rothblatt, Martine AChairperson & CEODirectSell3172026533.909,5005,072,01921,629,759Form
174Olian, Judy DDirectSell3162026535.44200107,0882,380,031Form
175Rothblatt, Martine AChairperson & CEODirectSell3162026534.99516276,0534,501,378Form
176Rothblatt, Martine AChairperson & CEODirectSell3162026538.009,5005,110,96769,940Form
177Rothblatt, Martine AChairperson & CEODirectSell3162026537.978,9844,833,09569,936Form
178Rothblatt, Martine AChairperson & CEODirectSell3112026539.549,5005,125,64770,140Form
179Rothblatt, Martine AChairperson & CEODirectSell3112026539.719,5005,127,27370,163Form
180Olian, Judy DDirectSell3092026510.00200102,0002,368,950Form
181Rothblatt, Martine AChairperson & CEODirectSell3092026484.559,5004,603,23262,992Form
182Mahon, Paul AEVP & GENERAL COUNSELDirectSell3052026483.168,3004,010,18717,801,366Form
183Rothblatt, Martine AChairperson & CEODirectSell3052026317.9719,0006,041,41441,336Form
184Kurzweil, RayDirectSell3052026489.024,9102,401,0886,195,883Form
185Thompson, Tommy GDirectSell3052026489.422,000978,8394,150,279Form
186Causey, ChristopherDirectSell3052026490.17209,8032,053,806Form
187Rothblatt, Martine AChairperson & CEODirectSell3052026499.429,5004,744,46764,924Form
188Olian, Judy DDirectSell3022026509.55200101,9102,468,770Form
189Causey, ChristopherDirectSell2252026520.001,000520,0002,178,800Form
190Benkowitz, MichaelPRESIDENT AND COOby TrustSell2242026472.1314,440  Form
191Benkowitz, MichaelPRESIDENT AND COOby TrustSell2182026480.7522,500  Form
192Malcolm, JanDirectSell2172026474.685023,734104,430Form
193Benkowitz, MichaelPRESIDENT AND COOby TrustSell2102026474.6522,500  Form
194Mahon, Paul AEVP & GENERAL COUNSELDirectSell2052026483.258,3004,010,94017,774,262Form
195Malcolm, JanDirectSell2032026474.235023,712128,042Form
196Benkowitz, MichaelPRESIDENT AND COOby TrustSell2032026470.9522,500  Form
197Benkowitz, MichaelPRESIDENT AND COOby TrustSell1282026471.9122,500  Form
198Benkowitz, MichaelPRESIDENT AND COOby TrustSell1282026464.667,875  Form
199Benkowitz, MichaelPRESIDENT AND COOby TrustSell1282026464.6614,625  Form
200Malcolm, JanDirectSell1202026460.985023,049147,514Form
201Benkowitz, MichaelPRESIDENT AND COOby TrustSell1132026479.5122,500  Form
202Benkowitz, MichaelPRESIDENT AND COOby TrustSell1072026487.3814,625  Form
203Benkowitz, MichaelPRESIDENT AND COOby TrustSell1072026487.387,875  Form
204Causey, ChristopherDirectSell1062026510.001,000510,0002,136,900Form
205Malcolm, JanDirectSell1062026495.015024,750183,154Form
206Causey, ChristopherDirectSell1052026500.011,000500,0152,095,061Form
207Mahon, Paul AEVP & GENERAL COUNSELDirectSell1022026485.438,3004,029,07617,854,633Form
208Benkowitz, MichaelPRESIDENT AND COOby TrustSell12302025502.7922,500  Form
209Mahon, Paul AEVP & GENERAL COUNSELDirectSell12292025513.1811,0005,644,95418,875,186Form
210Benkowitz, MichaelPRESIDENT AND COOby TrustSell12292025514.3522,500  Form
211Malcolm, JanDirectSell12232025512.125025,606215,090Form
212Sullivan, Louis Wby TrustSell12232025512.135,950  Form
213Rothblatt, Martine AChairperson & CEODirectSell12192025507.072,0001,014,14365,919Form
214Thompson, Tommy GDirectSell12192025500.59910455,5334,244,968Form
215Rothblatt, Martine AChairperson & CEODirectSell12192025508.874,0002,035,48866,153Form
216Rothblatt, Martine AChairperson & CEODirectSell12192025501.044,0002,004,14765,135Form
217Rothblatt, Martine AChairperson & CEODirectSell12162025493.454,0001,973,82064,149Form
218Edgemond, JamesCFO AND TREASURERDirectSell12162025495.363,5171,742,1934,033,248Form
219Rothblatt, Martine AChairperson & CEODirectSell12162025494.724,0001,978,86964,313Form
220Benkowitz, MichaelPRESIDENT AND COOby TrustSell12162025496.3022,500  Form
221Patusky, ChristopherDirectSell12162025495.951,000495,954738,971Form
222Rothblatt, Martine AChairperson & CEODirectSell12122025490.704,0001,962,78363,790Form
223Malcolm, JanDirectSell12122025482.985024,149227,001Form
224Mahon, Paul AEVP & GENERAL COUNSELDirectSell12122025484.6711,0005,331,31617,826,465Form
225Rothblatt, Martine AChairperson & CEODirectSell12122025483.974,0001,935,87962,916Form
226Rothblatt, Martine AChairperson & CEODirectSell12102025480.054,0001,920,19162,406Form
227Mesa, NildaDirectSell12102025481.6318790,0652,545,897Form
228Rothblatt, Martine AChairperson & CEODirectSell12102025478.304,0001,913,18462,178Form
229Edgemond, JamesCFO AND TREASURERDirectSell12092025478.6021,00010,050,5973,896,760Form
230Benkowitz, MichaelPRESIDENT AND COOby TrustSell12092025478.5822,500  Form
231Rothblatt, Martine AChairperson & CEODirectSell12082025484.234,0001,936,93662,950Form
232Rothblatt, Martine AChairperson & CEODirectSell12082025483.284,0001,933,12062,826Form
233Rothblatt, Martine AChairperson & CEODirectSell12052025480.014,0001,920,04362,401Form
234Rothblatt, Martine AChairperson & CEODirectSell12052025475.274,0001,901,08761,785Form
235Rothblatt, Martine AChairperson & CEODirectSell12022025481.294,0001,925,14362,567Form
236Edgemond, JamesCFO AND TREASURERDirectSell12022025479.9921,00010,079,6963,908,042Form
237Rothblatt, Martine AChairperson & CEODirectSell12022025481.934,0001,927,70362,650Form
238Benkowitz, MichaelPRESIDENT AND COOby TrustSell12022025479.9122,500  Form
239Rothblatt, Martine AChairperson & CEODirectSell12012025487.644,0001,950,55063,393Form
240Rothblatt, Martine AChairperson & CEODirectSell12012025485.054,0001,940,20463,057Form
241Mahon, Paul AEVP & GENERAL COUNSELDirectSell11262025486.0611,0005,346,70117,877,911Form
242Edgemond, JamesCFO AND TREASURERDirectSell11262025473.6421,0009,946,5443,856,417Form
243Benkowitz, MichaelPRESIDENT AND COOby TrustSell11262025473.6622,500  Form
244Rothblatt, Martine AChairperson & CEODirectSell11252025475.334,0001,901,30561,792Form
245Rothblatt, Martine AChairperson & CEODirectSell11252025470.784,0001,883,11461,201Form
246Rothblatt, Martine AChairperson & CEODirectSell11212025474.644,0001,898,55861,703Form
247Rothblatt, Martine AChairperson & CEODirectSell11212025478.384,0001,913,52462,190Form
248Rothblatt, Martine AChairperson & CEODirectSell11202025474.584,0001,898,33661,696Form
249Rothblatt, Martine AChairperson & CEODirectSell11202025472.764,0001,891,03761,459Form
250Benkowitz, MichaelPRESIDENT AND COOby TrustSell11182025470.4322,500  Form
251Edgemond, JamesCFO AND TREASURERDirectSell11182025470.3621,0009,877,5353,818,373Form
252Rothblatt, Martine AChairperson & CEODirectSell11182025467.554,0001,870,19260,781Form
253Rothblatt, Martine AChairperson & CEODirectSell11182025462.944,0001,851,77460,183Form
254Rothblatt, Martine AChairperson & CEODirectSell11132025728.964,0002,915,85994,765Form
255Mahon, Paul AEVP & GENERAL COUNSELDirectSell11132025464.7611,0005,112,33517,094,255Form
256Rothblatt, Martine AChairperson & CEODirectSell11132025460.004,0001,839,99659,800Form
257Rothblatt, Martine AChairperson & CEODirectSell11122025451.824,0001,807,28358,737Form
258Benkowitz, MichaelPRESIDENT AND COOby TrustSell11122025452.0722,500  Form
259Edgemond, JamesCFO AND TREASURERDirectSell11122025452.0721,0009,493,4833,669,909Form
260Rothblatt, Martine AChairperson & CEODirectSell11122025448.394,0001,793,54658,290Form
261Rothblatt, Martine AChairperson & CEODirectSell11072025448.254,0001,793,00858,273Form
262Rothblatt, Martine AChairperson & CEODirectSell11072025448.584,0001,794,30858,315Form
263Rothblatt, Martine AChairperson & CEODirectSell11062025437.984,0001,751,92256,937Form
264Rothblatt, Martine AChairperson & CEODirectSell11062025434.134,0001,736,50156,436Form
265Edgemond, JamesCFO AND TREASURERDirectSell11052025436.0921,0009,157,8213,540,152Form
266Rothblatt, Martine AChairperson & CEODirectSell11042025438.304,0001,753,19456,979Form
267Benkowitz, MichaelPRESIDENT AND COOby TrustSell11042025429.2522,500  Form
268Rothblatt, Martine AChairperson & CEODirectSell11042025450.354,0001,801,39858,545Form
269Rothblatt, Martine AChairperson & CEODirectSell10302025448.964,0001,795,83758,365Form
270Mahon, Paul AEVP & GENERAL COUNSELDirectSell10302025450.3411,0004,953,76016,564,024Form
271Rothblatt, Martine AChairperson & CEODirectSell10302025435.784,0001,743,11256,651Form
272Rothblatt, Martine AChairperson & CEODirectSell10302025415.394,0001,661,55554,001Form
273Rothblatt, Martine AChairperson & CEODirectSell10302025415.544,0001,662,17354,021Form
274Benkowitz, MichaelPRESIDENT AND COOby TrustSell10282025417.5022,500  Form
275Rothblatt, Martine AChairperson & CEODirectSell10272025424.064,0001,696,25955,128Form
276Rothblatt, Martine AChairperson & CEODirectSell10272025422.184,0001,688,73054,884Form
277Rothblatt, Martine AChairperson & CEODirectSell10222025422.154,0001,688,60754,880Form
278Rothblatt, Martine AChairperson & CEODirectSell10222025427.764,0001,711,04355,609Form
279Benkowitz, MichaelPRESIDENT AND COOby TrustSell10212025427.4122,500  Form
280Rothblatt, Martine AChairperson & CEODirectSell10202025424.594,0001,698,35055,196Form
281Rothblatt, Martine AChairperson & CEODirectSell10202025430.674,0001,722,68755,987Form
282Mahon, Paul AEVP & GENERAL COUNSELDirectSell10202025431.5011,0004,746,49415,870,982Form
283Rothblatt, Martine AChairperson & CEODirectSell10162025431.314,0001,725,25356,071Form
284Rothblatt, Martine AChairperson & CEODirectSell10162025435.294,0001,741,16456,588Form
285Rothblatt, Martine AChairperson & CEODirectSell10152025437.474,0001,749,87456,871Form
286Rothblatt, Martine AChairperson & CEODirectSell10152025440.434,0001,761,73057,256Form
287Benkowitz, MichaelPRESIDENT AND COOby TrustSell10152025440.3522,500  Form
288Rothblatt, Martine AChairperson & CEODirectSell10102025444.704,0001,778,78857,811Form
289Rothblatt, Martine AChairperson & CEODirectSell10102025448.914,0001,795,65558,359Form
290Rothblatt, Martine AChairperson & CEODirectSell10082025450.864,0001,803,44958,612Form
291Rothblatt, Martine AChairperson & CEODirectSell10082025451.834,0001,807,32058,738Form
292Benkowitz, MichaelPRESIDENT AND COOby TrustSell10072025450.2422,500  Form
293Rothblatt, Martine AChairperson & CEODirectSell10062025449.694,0001,798,76558,460Form
294Rothblatt, Martine AChairperson & CEODirectSell10062025446.214,0001,784,84758,008Form
295Rothblatt, Martine AChairperson & CEODirectSell10022025434.884,0001,739,52556,535Form
296Mahon, Paul AEVP & GENERAL COUNSELDirectSell10022025436.6011,0004,802,57416,058,497Form
297Rothblatt, Martine AChairperson & CEODirectSell10022025425.454,0001,701,79755,308Form
298Rothblatt, Martine AChairperson & CEODirectSell10012025422.844,0001,691,35854,969Form
299Benkowitz, MichaelPRESIDENT AND COOby TrustSell10012025421.8022,500  Form
300Rothblatt, Martine AChairperson & CEODirectSell10012025425.634,0001,702,52755,332Form

Investor Activity (13F)

Updated Oct 31, 2026
13F holdings as of Mar 31, 2026 (Q1 2026)

Active managers (13F portfolio over $250M, at least 3 holdings) with a position over $5M that is either over 10% of their portfolio or held in a concentrated book of 50 or fewer total positions. Index/ETF, sovereign, bank, community-bank and charitable/donor-advised filers are excluded.

Active ManagerValue% of PortfolioTotal PositionsQoQFiling
Avoro Capital Advisors LLC$1.6 Bil15.4%30Hold13F
Eversept Partners, LP$156.7 Mil10.3%104Hold13F
Nepsis Inc.$25.0 Mil8.4%29Hold13F
First Turn Management, LLC$62.1 Mil6.9%33ADD +64.7%13F
Tri Locum Partners LP$41.7 Mil5.9%17TRIM -41.8%13F
Summit Street Capital Management, LLC$33.7 Mil4.8%31Hold13F
Elmind Capital, LP$8.9 Mil2.5%34ADD +36.4%13F
Active ManagerValue% of PortfolioTotal PositionsQoQFiling
First Turn Management, LLC$62.1 Mil6.9%33ADD +64.7%13F
Elmind Capital, LP$8.9 Mil2.5%34ADD +36.4%13F
Active ManagerValue% of PortfolioTotal PositionsQoQFiling
Tri Locum Partners LP$41.7 Mil5.9%17TRIM -41.8%13F
Active ManagerValue% of PortfolioTotal PositionsQoQFiling
Avoro Capital Advisors LLC$1.6 Bil15.4%30Hold13F
Eversept Partners, LP$156.7 Mil10.3%104Hold13F
First Turn Management, LLC$62.1 Mil6.9%33ADD +64.7%13F
Tri Locum Partners LP$41.7 Mil5.9%17TRIM -41.8%13F
Summit Street Capital Management, LLC$33.7 Mil4.8%31Hold13F
Nepsis Inc.$25.0 Mil8.4%29Hold13F
Elmind Capital, LP$8.9 Mil2.5%34ADD +36.4%13F
Core Cache Last Updated: 10/30/2026