Tearsheet

Ascendis Pharma (ASND)


Market Price (9/4/2025): $200.1 | Market Cap: $12.1 Bil
Sector: Health Care | Industry: Biotechnology

Ascendis Pharma (ASND)


Market Price (9/4/2025): $200.1
Market Cap: $12.1 Bil
Sector: Health Care
Industry: Biotechnology

Investment Highlights

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Market Valuation

 9/4/252024202320222021
Share Price CYE$200.10$137.67$125.95$122.13$134.53
Market Cap CYE ($ Bil)12.18.27.16.87.6
Total Debt ($ Bil)0.00.90.60.50.1
Total Cash ($ Bil)0.00.60.40.70.7
Enterprise Value ($ Bil)0.09.17.77.37.7
Valuation Ratios     
P/S TTM28.421.926.6133.8947.3
P/EBIT TTM-58.5-25.9-16.5-12.5-19.4
P/E TTM-42.3-21.1-14.7-11.7-19.2
Sector Ratios     
P/S TTM (Sector)3.84.14.54.56.7
P/EBIT TTM (Sector)4.30.4-1.9-1.2-0.4
P/E TTM (Sector)-1.8-2.2-3.4-2.2-2.3
 9/4/2520242023
Share Price CYE$200.10$137.67$125.95
Market Cap CYE ($ Bil)12.18.27.1
Total Debt ($ Bil)0.00.90.6
Total Cash ($ Bil)0.00.60.4
Enterprise Value ($ Bil)0.09.17.7
Valuation Ratios   
P/S TTM28.421.926.6
P/EBIT TTM-58.5-25.9-16.5
P/E TTM-42.3-21.1-14.7
Sector Ratios   
P/S TTM (Sector)3.84.14.5
P/EBIT TTM (Sector)4.30.4-1.9
P/E TTM (Sector)-1.8-2.2-3.4

Business Description

Ascendis Pharma A/S, a biopharmaceutical company, focuses on developing therapeutics for unmet medical needs. The company offers SKYTROFA for treating patients with growth hormone deficiency (GHD). It also develops TransCon Growth Hormone (hGH) for pediatric GHD in Japan; TransCon hGH for adults with GHD; TransCon parathyroid hormone for adult hypoparathyroidism; and TransCon CNP for pediatric achondroplasia. Show more

Price Returns Compared

Expand for Detailed View

 202020212022202320242025Total [1]
Returns
ASND Return20%-19%-9%3%9%45%-8%
Peers Return11%18%23%15%2%8%103%
S&P 500 Return16%27%-19%24%23%10%100%

[1] Cumulative total returns since the beginning of 2020
[2] Peers: VRTX, ABBV, AMGN, GILD, REGN.
[3] 2025 data is for the year up to 9/3/2025 (YTD)

Recent Active Movers

Recent Active Movers

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Peer Comparisons for Ascendis Pharma

Financials

ASNDVRTXABBVAMGNGILDREGNMedian
NameAscendis.Vertex P.AbbVie Amgen Gilead S.Regenero. 
Mkt Price-401.00211.92286.92112.71577.90286.92
Mkt Cap-102.9374.7154.4140.360.7140.3
Rev LTM-11,41958,32834,91728,86214,21428,862
Op Inc LTM--19913,6958,19210,7973,8418,192
FCF LTM-3,50018,23910,6059,3693,5569,369
FCF 3Y Avg-1,98420,2738,5908,3973,2488,397
CFO LTM-3,84619,28312,0139,8684,7449,868
CFO 3Y Avg-2,32421,1549,7538,9494,5188,949

Growth & Margins

ASNDVRTXABBVAMGNGILDREGNMedian
NameAscendis.Vertex P.AbbVie Amgen Gilead S.Regenero. 
Rev Chg LTM-10.5%6.1%12.9%3.8%5.4%6.1%
Rev Chg 3Y Avg-11.0%0.6%10.0%1.6%0.3%1.6%
Rev Chg Q-12.1%6.6%9.4%1.8%3.6%6.6%
QoQ Delta Rev Chg LTM-2.9%1.7%2.3%0.4%0.9%1.7%
Op Mgn LTM--1.7%23.5%23.5%37.4%27.0%23.5%
Op Mgn 3Y Avg-26.5%27.2%26.4%39.2%30.1%27.2%
QoQ Delta Op Mgn LTM-2.0%1.0%1.6%-0.0%-0.2%1.0%
CFO/Rev LTM-33.7%33.1%34.4%34.2%33.4%33.7%
CFO/Rev 3Y Avg-22.5%37.5%32.0%31.9%33.6%32.0%
FCF/Rev LTM-30.6%31.3%30.4%32.5%25.0%30.6%
FCF/Rev 3Y Avg-19.2%36.0%28.2%30.0%24.1%28.2%

Valuation

ASNDVRTXABBVAMGNGILDREGNMedian
NameAscendis.Vertex P.AbbVie Amgen Gilead S.Regenero. 
Mkt Cap-102.9374.7154.4140.360.7140.3
P/S-9.06.44.44.94.34.9
P/EBIT-23.463.614.917.112.417.1
P/E-28.399.623.322.213.623.3
P/CFO-26.819.412.814.212.814.2
Total Yield-3.5%4.0%7.5%7.3%7.6%7.3%
Dividend Yield-0.0%3.0%3.2%2.8%0.3%2.8%
FCF Yield 3Y Avg-2.1%7.3%6.2%8.0%4.4%6.2%
D/E-0.00.20.40.20.00.2
Net D/E--0.00.20.30.1-0.10.1

Returns

ASNDVRTXABBVAMGNGILDREGNMedian
NameAscendis.Vertex P.AbbVie Amgen Gilead S.Regenero. 
1M Rtn--13.2%8.6%-2.6%-0.4%3.6%-0.4%
3M Rtn--10.2%14.2%-0.1%3.8%18.6%3.8%
6M Rtn--17.5%3.8%-6.5%-0.4%-14.2%-6.5%
12M Rtn--19.1%11.8%-11.2%47.3%-51.0%-11.2%
3Y Rtn-42.7%74.1%30.3%97.4%-0.0%42.7%
1M Excs Rtn--16.1%5.7%-5.4%-3.3%0.7%-3.3%
3M Excs Rtn--18.1%6.2%-7.8%-3.9%9.8%-3.9%
6M Excs Rtn--26.7%-7.7%-15.8%-11.1%-25.0%-15.8%
12M Excs Rtn--32.8%-2.4%-24.7%33.4%-66.3%-24.7%
3Y Excs Rtn--15.1%17.5%-24.3%45.4%-56.7%-15.1%

Financials

Segment Financials

Revenue by Segment

$ Mil20242023202220212020
SKYTROFA®17936   
Collaboration partners and license agreements8816   
YORVIPATH®00   
Licenses  231
Rendering of services  1210
Sale of clinical supply  423
Sale of commercial products  1  
Total267518713


Price Behavior

Short Interest

Short Interest: As Of Date8152025
Short Interest: Shares Quantity2,487,423
Short Interest: % Change Since 7312025-9.7%
Average Daily Volume622,417
Days-to-Cover Short Interest4
Basic Shares Quantity60,454,589
Short % of Basic Shares4.1%