Scribe Therapeutics (SCTX)


Market Price (8/6/2026): $24.03 | Market Cap: $-Sector: Health Care | Industry: Biotechnology

Scribe Therapeutics (SCTX)


Market Price (8/6/2026): $24.03
Market Cap: $-
Sector: Health Care
Industry: Biotechnology

Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.

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Megatrend and thematic drivers
Megatrends include Biotechnology & Genomics, and Precision Medicine. Themes include Gene Editing & Therapy, Targeted Therapies, Show more.

Trading close to highs
Dist 52W High is 0.0%, Dist 3Y High is 0.0%

Weak multi-year price returns
2Y Excs Rtn is -30%, 3Y Excs Rtn is -58%

High stock price volatility
Vol 12M is 127%

Key risks
SCTX key risks include [1] potential failure of its lead candidate, Show more.

0 Megatrend and thematic drivers
Megatrends include Biotechnology & Genomics, and Precision Medicine. Themes include Gene Editing & Therapy, Targeted Therapies, Show more.
1 Trading close to highs
Dist 52W High is 0.0%, Dist 3Y High is 0.0%
2 Weak multi-year price returns
2Y Excs Rtn is -30%, 3Y Excs Rtn is -58%
3 High stock price volatility
Vol 12M is 127%
4 Key risks
SCTX key risks include [1] potential failure of its lead candidate, Show more.

Valuation & Metrics

Price Chart

Why The Stock Moved

Qualitative Assessment

AI Analysis | Feedback

Updated on 8/5/2026

Scribe Therapeutics (SCTX) stock has gained about 10% since it went public on 7/24/2026 because of the following key factors:

1. Strong Investor Demand During Upsized IPO: Scribe Therapeutics priced its initial public offering at $15.00 per share, at the high end of its proposed range, and upsized the offering to 8.58 million shares, raising approximately $128.7 million. This demonstrated robust investor interest from the outset. The stock then surged nearly 67% on its first trading day, July 24, 2026, opening at $25.00 and closing at $21.65, a 44.33% gain from its IPO price, setting a strong positive foundation for subsequent trading.

2. Significant Strategic Investment and Validation from Pharmaceutical Giants: Sanofi solidified its commitment to Scribe by purchasing 500,000 shares for $7.5 million in a concurrent private placement at the IPO price, signaling strong confidence in the company's technology and pipeline. Additionally, Eli Lilly and Company indicated an interest in acquiring shares that, combined with its existing holdings, would amount to a 10.9% stake in Scribe, further validating the biotech's potential.

Show more
Updated on 8/5/2026

Scribe Therapeutics (SCTX) stock has gained about 10% since it went public on 7/24/2026 because of the following key factors:

1. Strong Investor Demand During Upsized IPO: Scribe Therapeutics priced its initial public offering at $15.00 per share, at the high end of its proposed range, and upsized the offering to 8.58 million shares, raising approximately $128.7 million. This demonstrated robust investor interest from the outset. The stock then surged nearly 67% on its first trading day, July 24, 2026, opening at $25.00 and closing at $21.65, a 44.33% gain from its IPO price, setting a strong positive foundation for subsequent trading.

2. Significant Strategic Investment and Validation from Pharmaceutical Giants: Sanofi solidified its commitment to Scribe by purchasing 500,000 shares for $7.5 million in a concurrent private placement at the IPO price, signaling strong confidence in the company's technology and pipeline. Additionally, Eli Lilly and Company indicated an interest in acquiring shares that, combined with its existing holdings, would amount to a 10.9% stake in Scribe, further validating the biotech's potential.

3. Cutting-Edge CRISPR-Based Gene Editing Technology and Promising Pipeline: Scribe Therapeutics leverages innovative in vivo CRISPR-based genetic medicine, with its lead candidate, STX-1150, aimed at silencing the PCSK9 gene to reduce "bad" cholesterol. The expectation of Phase 1 clinical trial results for STX-1150 in the first half of 2027 positions the company in a high-growth, high-impact area of cardiovascular disease treatment. The company's co-founder, Nobel Laureate Dr. Jennifer Doudna, also brings significant scientific credibility and expertise to its gene-editing platform.

4. Favorable Biotechnology IPO Market Conditions: Scribe's IPO occurred during an upswing in the biotechnology IPO market in 2026, with 14 companies having priced new stock issuances that year, surpassing previous annual totals. As the first gene-editing company to go public in over two years, Scribe's successful offering capitalized on this renewed investor appetite for innovative biotech firms, contributing to its strong debut and sustained positive momentum.

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Stock Movement Drivers

Fundamental Drivers

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Market Drivers

4/30/2026 to 8/5/2026
ReturnCorrelation
SCTX  
Market (SPY)7.1%38.2%
Sector (XLV)12.4%-39.5%

Fundamental Drivers

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Market Drivers

1/31/2026 to 8/5/2026
ReturnCorrelation
SCTX  
Market (SPY)11.5%38.2%
Sector (XLV)6.5%-39.5%

Fundamental Drivers

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Market Drivers

7/31/2025 to 8/5/2026
ReturnCorrelation
SCTX  
Market (SPY)22.8%38.2%
Sector (XLV)27.5%-39.5%

Fundamental Drivers

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Market Drivers

7/31/2023 to 8/5/2026
ReturnCorrelation
SCTX  
Market (SPY)74.1%38.2%
Sector (XLV)28.1%-39.5%

Return vs. Risk

Price Returns Compared

 202120222023202420252026Total [1]
Returns
SCTX Return-----2%2%
Peers Return0%-59%-5%-52%20%10%-76%
S&P 500 Return27%-19%24%23%16%13%106%

Monthly Win Rates [3]
SCTX Win Rate-----50% 
Peers Win Rate28%30%47%33%50%65% 
S&P 500 Win Rate75%42%67%75%67%50% 

Max Drawdowns [4]
SCTX Max Drawdown------ 
Peers Max Drawdown-46%-66%-55%-67%-61%-37% 
S&P 500 Max Drawdown-5%-25%-10%-8%-19%-9% 


[1] Cumulative total returns since the beginning of 2021
[2] Peers: NTLA, CRSP, BEAM, PRME, EDIT.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 8/5/2026 (YTD)

How Low Can It Go

SCTX has limited trading history. Below is the Health Care sector ETF (XLV) in its place.

EventXLVS&P 500
2025 US Tariff Shock
  % Loss-11.7%-18.8%
  % Gain to Breakeven13.3%23.1%
  Time to Breakeven142 days79 days
2022 Inflation Shock & Fed Tightening
  % Loss-13.8%-24.5%
  % Gain to Breakeven15.9%32.4%
  Time to Breakeven166 days427 days
2020 COVID-19 Crash
  % Loss-27.9%-33.7%
  % Gain to Breakeven38.8%50.9%
  Time to Breakeven77 days140 days
Q4 2018 Fed Policy Error / Growth Scare
  % Loss-15.0%-19.2%
  % Gain to Breakeven17.6%23.8%
  Time to Breakeven191 days105 days
2015-2016 China Devaluation / Global Growth Scare
  % Loss-15.9%-12.2%
  % Gain to Breakeven18.9%13.9%
  Time to Breakeven165 days62 days
2011 US Debt Ceiling Crisis & European Contagion
  % Loss-15.8%-17.9%
  % Gain to Breakeven18.8%21.8%
  Time to Breakeven153 days123 days

Compare to NTLA, CRSP, BEAM, PRME, EDIT

In The Past

State Street Health Care Select Sector SPDR ETF's stock fell -11.7% during the 2025 US Tariff Shock. Such a loss loss requires a 13.3% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

SCTX has limited trading history. Below is the Health Care sector ETF (XLV) in its place.

EventXLVS&P 500
2020 COVID-19 Crash
  % Loss-27.9%-33.7%
  % Gain to Breakeven38.8%50.9%
  Time to Breakeven77 days140 days
2008-2009 Global Financial Crisis
  % Loss-37.9%-53.4%
  % Gain to Breakeven61.1%114.4%
  Time to Breakeven767 days1085 days

Compare to NTLA, CRSP, BEAM, PRME, EDIT

In The Past

State Street Health Care Select Sector SPDR ETF's stock fell -11.7% during the 2025 US Tariff Shock. Such a loss loss requires a 13.3% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

About Scribe Therapeutics (SCTX)

Scribe Therapeutics (SCTX) Business Summary

Scribe Therapeutics is a clinical-stage biotechnology company focused on developing purpose-built in vivo CRISPR technologies for disease prevention and durable therapeutic intervention. Unlike many genetic medicine companies that primarily target rare disorders, Scribe aims to address common diseases affecting millions, particularly within the cardiovascular and metabolic space. They employ a proprietary "CRISPR by Design" approach, which integrates generative artificial intelligence and machine learning with massively parallel experimental validation to engineer optimal CRISPR-based solutions for specific therapeutic applications.

The company has developed two distinct, proprietary CRISPR technologies derived from a novel CRISPR-CasX enzyme: ELXR (Epigenetic Long-Term X-Repressor) for precise, durable epigenetic silencing without altering underlying DNA, and XE (X-Editor) for specific and efficient gene editing. Their lead product candidate, STX-1150, utilizes the ELXR technology to durably lower LDL-C (bad cholesterol) by repressing PCSK9 expression, targeting a significant driver of atherosclerotic cardiovascular disease (ASCVD). STX-1150 is designed to offer long-lasting benefits without permanent genetic changes, aiming to significantly improve patient adherence and outcomes. A first-in-human clinical trial for STX-1150 is currently underway in Australia, with initial data anticipated in the first half of 2027.

Beyond STX-1150, Scribe's pipeline includes two additional programs, STX-1200 and STX-1400, which utilize their XE gene editing technology to address other key lipid drivers of ASCVD: elevated lipoprotein(a) (Lp(a)) and severely high triglycerides. Scribe aims to transform the treatment paradigm for these prevalent conditions from symptom management to population-level prevention, offering durable and scalable genetic medicines. Their primary market consists of millions of patients suffering from or at risk of cardiovascular and metabolic diseases who could benefit from more effective, long-lasting, and adherence-friendly therapeutic options than currently available standard-of-care treatments.

AI Analysis | Feedback

Here are 1-2 brief analogies to describe Scribe Therapeutics:

Scribe Therapeutics is like a Google for genetic engineering, building its own foundational CRISPR 'operating system' to develop solutions for common diseases.

Scribe Therapeutics is a cutting-edge biotech aiming to be a Pfizer for genetic medicines, creating 'one-and-done' treatments for widespread conditions like heart disease.

AI Analysis | Feedback

  • STX-1150: An epigenetic silencing therapy (using ELXR technology) designed to durably lower LDL-C by repressing PCSK9 expression without altering DNA.
  • STX-1200: A gene editing therapy (using XE technology) in preclinical development targeting the LPA gene to reduce elevated lipoprotein(a), a key risk factor for ASCVD.
  • STX-1400: A gene editing therapy (using XE technology) in preclinical development targeting the APOC3 gene to reduce severely high triglycerides, a key risk factor for ASCVD.
  • ELXR (Epigenetic Long-Term X-Repressor): A proprietary epigenetic silencing technology designed for precise, durable gene repression without altering the underlying DNA sequence.
  • XE (X-Editor): A proprietary technology designed for specific and efficient gene editing.

AI Analysis | Feedback

Scribe Therapeutics (SCTX) is a clinical-stage biotechnology company. As such, it does not currently have commercialized products sold directly to individuals. Its primary "customers" and revenue sources come from strategic collaborations with other pharmaceutical companies.

The major customer companies identified are:

  • Sanofi (NYSE: SNY)
  • Eli Lilly and Company (NYSE: LLY)

AI Analysis | Feedback

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AI Analysis | Feedback

Benjamin L. Oakes, PhD, Co-founder, President and Chief Executive Officer Benjamin L. Oakes is a co-founder, President, and Chief Executive Officer at Scribe Therapeutics. He previously served as an Innovative Genomics Institute Entrepreneurial Fellow, where he focused on the holistic engineering of genome editing technologies. Dr. Oakes co-founded Scribe with Nobel laureate Jennifer Doudna and others, establishing a molecular engineering company dedicated to creating CRISPR-based therapies. He has contributed to over 35 publications and patent applications in synthetic biology, molecular engineering, CRISPR, and zinc finger-based genetic modification. He earned his Ph.D. in Molecular and Cellular Biology from the University of California, Berkeley, conducting research in the Doudna Lab and Savage Lab on CRISPR-Cas9 molecules. Scribe Therapeutics is backed by leading individual and institutional investors, including Andreessen Horowitz, Avoro Ventures, Avoro Capital Advisors, OrbiMed Advisors, Perceptive Advisors, T. Rowe Price Associates, Inc., Wellington Management, RA Capital Management, and Menlo Ventures. David Parrot, MBA, Chief Financial Officer David Parrot serves as the Chief Financial Officer at Scribe Therapeutics, joining the company in December 2021. He brings over 30 years of experience as an Investment Banker, advising life science companies on capital raising and strategic transactions. Before Scribe, Mr. Parrot was a managing director and Head of West Coast Life Science Investment Banking at Barclays. He also spent 11 years at Piper Jaffray as a senior member of their Biotechnology investment banking team and was a Managing Director of Investment Banking in the Healthcare Group at SunTrust Robinson Humphrey, focusing on the biotechnology sector. Svetlana Lucas, PhD, Chief Business Officer Svetlana Lucas is the Chief Business Officer at Scribe Therapeutics, contributing nearly 20 years of experience in strategy, commercialization, and business development leadership. Prior to joining Scribe, she was the Senior Vice President, Business Development at Tizona Therapeutics, Inc., a clinical-stage immunotherapy company, where she was responsible for the company's business development strategy and transactions, including a global strategic collaboration with AbbVie Inc.. Before her role at Tizona, Dr. Lucas was the Head of Oncology and Inflammation External R&D Team at Amgen Inc.. Sunny Mok, PhD, MBA, SVP of Operations Sunny Mok is the Senior Vice President of Operations at Scribe Therapeutics. Brett T. Staahl, PhD, Co-founder & VP, External Innovation Brett T. Staahl is a co-founder and the Vice President of External Innovation at Scribe Therapeutics. Previously, he held a Postdoctoral Fellow position in the lab of Jennifer Doudna, where he was instrumental in pioneering the use of CRISPR ribonucleoproteins and developing robust methods for their in vivo and ex vivo delivery to various cell types. He has also worked at and consulted for other biotech startups. Dr. Staahl has contributed to over 20 scientific publications and holds several patents. He received his Ph.D. in Developmental Biology from Stanford University. He co-founded Scribe with Nobel Laureate Jennifer Doudna, Benjamin L. Oakes, and David F. Savage.

AI Analysis | Feedback

  • The primary risk for Scribe Therapeutics, as a clinical-stage biotechnology company, is the potential for its product candidates, particularly STX-1150, to fail in clinical trials or to not receive regulatory approval. The company anticipates reporting initial data from its first-in-human clinical trial of STX-1150 in Australia in the first half of 2027. Unfavorable results or delays in clinical development and the subsequent inability to secure regulatory clearances in major markets would significantly impede its ability to commercialize its therapies.
  • Scribe Therapeutics operates in highly competitive markets, specifically the "multibillion-dollar LDL-C lowering landscape" for cardiovascular and metabolic diseases. Despite believing that current standards of care are insufficient, the company faces the challenge of competing with existing pharmaceutical therapies (small-molecule, antibody, and siRNA therapies) and other emerging genetic medicines. Achieving broad real-world impact and market adoption against established treatments with varying levels of efficacy, side effects, and adherence will be critical to its success.
  • A key risk lies in the successful development, protection, and enforcement of its proprietary CRISPR technologies, including ELXR and XE, derived from a novel CRISPR-CasX enzyme. The company's business model is predicated on these "purpose-built in vivo CRISPR technologies." Any challenges to its intellectual property portfolio, such as patent disputes or the inability to obtain necessary patents, or unforeseen complexities in scaling and manufacturing these novel genetic medicines, could significantly hinder its ability to develop and commercialize its product pipeline.

AI Analysis | Feedback

Other biotechnology companies advancing in vivo gene editing or other durable genetic medicine technologies for cardiovascular and metabolic diseases, particularly those with clinical-stage programs targeting the same genes and pathways (e.g., PCSK9, Lp(a), APOC3). For example, Verve Therapeutics is developing in vivo gene editing therapies to durably lower LDL-C and Lp(a), with lead candidates already in clinical trials. The success and earlier market entry of such competing platforms could capture market share or set a high bar for efficacy and safety, potentially undermining the competitive position and market opportunity of Scribe's lead candidates, STX-1150, STX-1200, and STX-1400.

AI Analysis | Feedback

Addressable Markets for Scribe Therapeutics' Main Products

For Scribe Therapeutics' lead product candidate, STX-1150, which is designed to lower LDL-C by repressing PCSK9, the addressable market for PCSK9-based LDL-C lowering medicines currently exceeds $5 billion annually. The specific region (e.g., U.S. or global) for this market size is not explicitly stated in the provided information. For STX-1200, targeting elevated lipoprotein(a) (Lp(a)), and STX-1400, targeting severely high triglycerides by editing the LPA and APOC3 genes respectively, the company states that these programs address "key risk factors for ASCVD affecting large populations". However, a specific quantifiable market size in dollar figures for these products is not provided in the available information.

AI Analysis | Feedback

Scribe Therapeutics (SCTX) has several expected drivers of future revenue growth over the next 2-3 years, primarily stemming from the advancement of its clinical pipeline and the continued realization of milestone payments from strategic collaborations.

  1. Advancement of Lead Product Candidate STX-1150: Scribe Therapeutics' lead product candidate, STX-1150, is currently in a first-in-human clinical trial in Australia for adults with elevated LDL-C and increased risk of atherosclerotic cardiovascular disease (ASCVD). The company anticipates reporting initial data from this trial, including safety, tolerability, and LDL-C-lowering activity, in the first half of 2027. Positive clinical trial results and subsequent progression through development stages for STX-1150, which targets a multi-billion dollar LDL-C lowering market, are expected to be a significant driver of future revenue.
  2. Initiation of Clinical Trials for STX-1200 and STX-1400: Scribe's next programs, STX-1200 and STX-1400, target elevated lipoprotein(a) (Lp(a)) and high triglycerides, respectively, using their X-Editor (XE) technology. The company anticipates initiating a Phase 1 clinical trial for one of these programs as early as 2027 and the other in 2028. The progression of these programs into human trials expands Scribe's pipeline into additional large and significant markets for ASCVD, creating new potential revenue streams upon successful development.
  3. Achievement of Milestone Payments from Strategic Collaborations: Scribe Therapeutics has established strategic collaborations with major pharmaceutical companies, including Sanofi and Eli Lilly. These partnerships involve upfront and milestone payments as programs advance. Scribe has already achieved multiple success milestones, including one for an in vivo program with Sanofi in January 2025 and a second success milestone with Eli Lilly for an in vivo program in February 2026. Scribe is eligible to receive over $1.2 billion in potential milestone payments from Sanofi and over $1.5 billion from Eli Lilly, along with future royalties. Continued progress and achievement of further research, development, regulatory, and commercial milestones within these collaborations are expected to generate significant revenue.

AI Analysis | Feedback

Share Issuance

  • Scribe Therapeutics has raised approximately $150.0 million in equity financing since its founding in 2017.
  • The company has undertaken only one dilutive financing in the past four years.

Inbound Investments

  • The California Institute for Regenerative Medicine (CIRM) awarded Scribe Therapeutics grant funding of up to approximately $25.7 million to support the development and manufacturing of its STX-1200 and STX-1400 programs.
  • The company's operating model is complemented by upfront and milestone payments from strategic collaborations, including those with Sanofi and Lilly.

Recent Active Movers

Peer Comparisons

Peers to compare with:

Financials

SCTXNTLACRSPBEAMPRMEEDITMedian
NameScribe T.Intellia.CRISPR T.Beam The.Prime Me.Editas M. 
Mkt Price23.8010.9752.4527.073.082.7517.39
Mkt Cap-1.35.12.80.50.31.3
Rev LTM-661115643939
Op Inc LTM--421-534-378-207-89-378
FCF LTM--364-374-373-159-141-364
FCF 3Y Avg--388-284-294-157-169-284
CFO LTM--363-370-359-156-141-359
CFO 3Y Avg--382-272-281-151-165-272

Growth & Margins

SCTXNTLACRSPBEAMPRMEEDITMedian
NameScribe T.Intellia.CRISPR T.Beam The.Prime Me.Editas M. 
Rev Chg LTM-45.0%-68.6%158.9%4.9%8.0%8.0%
Rev Chg 3Y Avg-10.0%-44.5%138.6%-54.7%32.4%
Rev Chg Q--9.5%--94.2%-41.1%-39.2%-40.2%
QoQ Delta Rev Chg LTM--2.3%1,000.0%-4.9%-12.9%-4.5%-4.5%
Op Inc Chg LTM-22.2%3.3%15.2%-0.0%57.0%15.2%
Op Inc Chg 3Y Avg--1.3%-9.1%-25.0%-16.5%21.1%-9.1%
Op Mgn LTM--636.6%-4,857.6%-242.3%-5,121.8%-230.1%-636.6%
Op Mgn 3Y Avg--935.8%-2,204.5%-344.8%-14,755.0%-358.4%-935.8%
QoQ Delta Op Mgn LTM-15.1%59,781.9%-15.7%-623.7%15.1%15.1%
CFO/Rev LTM--549.5%-3,359.8%-230.3%-3,877.5%-363.1%-549.5%
CFO/Rev 3Y Avg--715.9%-1,449.5%-280.5%-12,998.2%-385.0%-715.9%
FCF/Rev LTM--550.2%-3,398.2%-238.9%-3,935.1%-364.6%-550.2%
FCF/Rev 3Y Avg--727.1%-1,487.8%-290.8%-13,591.8%-394.3%-727.1%

Valuation

SCTXNTLACRSPBEAMPRMEEDITMedian
NameScribe T.Intellia.CRISPR T.Beam The.Prime Me.Editas M. 
Mkt Cap-1.35.12.80.50.31.3
P/S-19.7460.218.1135.27.019.7
P/Op Inc--3.1-9.5-7.5-2.6-3.0-3.1
P/EBIT--3.1-9.5-7.5-2.6-2.6-3.1
P/E--3.3-11.2-33.1-2.7-2.5-3.3
P/CFO--3.6-13.7-7.9-3.5-1.9-3.6
Total Yield--30.4%-8.9%-3.0%-36.4%-40.5%-30.4%
Dividend Yield-0.0%0.0%0.0%0.0%0.0%0.0%
FCF Yield 3Y Avg--25.7%-6.0%-13.0%-32.0%-67.3%-25.7%
D/E-0.10.20.10.20.10.1
Net D/E--0.2-0.3-0.3-0.0-0.4-0.3

Returns

SCTXNTLACRSPBEAMPRMEEDITMedian
NameScribe T.Intellia.CRISPR T.Beam The.Prime Me.Editas M. 
1M Rtn9.9%-38.5%-15.3%-23.4%-22.8%-24.7%-23.1%
3M Rtn9.9%-20.8%-4.8%-16.3%-9.7%-13.4%-11.5%
6M Rtn9.9%-11.2%4.5%0.4%-11.4%41.0%2.5%
12M Rtn9.9%-5.3%-5.6%44.8%-29.5%5.8%0.3%
3Y Rtn9.9%-72.3%2.9%-0.2%-77.6%-69.6%-34.9%
1M Excs Rtn7.0%-40.0%-16.6%-31.5%-25.7%-29.6%-27.7%
3M Excs Rtn3.5%-24.0%-6.3%-12.7%-15.5%-15.9%-14.1%
6M Excs Rtn-1.7%-27.6%-10.8%-14.6%-30.8%21.8%-12.7%
12M Excs Rtn-12.1%-31.5%-34.0%19.6%-53.6%-14.6%-23.0%
3Y Excs Rtn-58.4%-142.4%-76.8%-80.6%-147.9%-137.0%-108.8%

Comparison Analyses

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Financials

Segment Financials

Revenue by Segment
$ Mil20252024
Researching and developing genetic medicines using CRISPR-based tools5127
Total5127


Net Income by Segment
$ Mil20252024
Researching and developing genetic medicines using CRISPR-based tools-22-48
Total-22-48


Price Behavior

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SCTX Betas & Captures as of 7/31/2026

 1M2M3M6M1Y3Y
Beta-0.281.337.70-1.731.39-0.63
Up Beta-13.2210.8819.80-1.77-14.76-1.24
Down Beta
Up Capture-172%-72%-45%-19%-8%-1%
Bmk +ve Days11223567138427
Stock +ve Days222222
Down Capture-27%-11%-10%-5%-3%-2%
Bmk -ve Days11212859114326
Stock -ve Days333333

[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with SCTX
SCTX10.0%127.4%2.88-
Sector ETF (XLV)25.1%15.6%1.24-39.5%
Equity (SPY)23.1%12.9%1.3438.2%
Gold (GLD)25.4%28.3%0.7953.0%
Commodities (DBC)29.5%19.8%1.1934.0%
Real Estate (VNQ)14.4%13.7%0.74-25.8%
Bitcoin (BTCUSD)-44.6%42.9%-1.2560.0%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 5-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with SCTX
SCTX1.9%127.4%2.88-
Sector ETF (XLV)6.1%15.0%0.23-39.5%
Equity (SPY)13.4%17.2%0.6038.2%
Gold (GLD)18.2%18.6%0.7953.0%
Commodities (DBC)8.1%19.6%0.3134.0%
Real Estate (VNQ)2.5%18.9%0.03-25.8%
Bitcoin (BTCUSD)9.9%53.0%0.3760.0%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 10-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with SCTX
SCTX1.0%127.4%2.88-
Sector ETF (XLV)10.0%16.6%0.49-39.5%
Equity (SPY)15.3%17.9%0.7338.2%
Gold (GLD)12.0%16.2%0.6053.0%
Commodities (DBC)7.1%18.0%0.3134.0%
Real Estate (VNQ)4.9%20.7%0.20-25.8%
Bitcoin (BTCUSD)58.2%66.2%0.9860.0%

Smart multi-asset allocation framework can stack odds in your favor. Learn How

SEC Filings

Expand for More
Report DateFiling DateFiling
03/31/202607/02/2026S-1
Collapse to Preview
Report DateFiling DateFiling
03/31/202607/02/2026S-1

Insider Activity

Updated 7/29/2026
Expand for More
#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Ah, Bio Fund Ii, LPAH Bio Fund II, L.P.Buy729202615.00333,3334,999,99535,776,125Form
2Gordon, Carl LSee footnotesBuy729202615.001,000,00015,000,00020,232,375Form
3Orbimed, Advisors LlcSee footnotesBuy729202615.001,000,00015,000,00020,232,375Form
4Aghazadeh, BehzadSee footnotesBuy728202618.257,905144,26656,372,206Form
5Aghazadeh, BehzadSee footnotesBuy728202615.152,383,33336,115,49546,687,234Form
Collapse to Preview
#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Ah, Bio Fund Ii, LPAH Bio Fund II, L.P.Buy729202615.00333,3334,999,99535,776,125Form
2Gordon, Carl LSee footnotesBuy729202615.001,000,00015,000,00020,232,375Form
3Orbimed, Advisors LlcSee footnotesBuy729202615.001,000,00015,000,00020,232,375Form
4Aghazadeh, BehzadSee footnotesBuy728202618.257,905144,26656,372,206Form
5Aghazadeh, BehzadSee footnotesBuy728202615.152,383,33336,115,49546,687,234Form
6Lucas, SvetlanaChief Business OfficerSpouseBuy727202615.003,00045,00045,000Form
7Parrot, DavidChief Financial OfficerSpouseBuy727202615.001,33319,99519,995Form
8Parrot, DavidChief Financial OfficerChildBuy727202615.001,33319,99519,995Form
Core Cache Last Updated: 8/5/2026