Tearsheet

Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.

0

Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -61%

Megatrend and thematic drivers
Megatrends include Biotechnology & Genomics, Precision Medicine, and Aging Population & Chronic Disease. Themes include Gene Editing & Therapy, Show more.

Weak multi-year price returns
2Y Excs Rtn is -34%, 3Y Excs Rtn is -138%

Meaningful short interest
Short Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 18%

Very low revenue
Rev LTMTotal Revenue or Sales, Last Twelve Months is 0

Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -374 Mil

Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -115%

High stock price volatility
Vol 12M is 1699%

Key risks
VOR key risks include [1] a distressed financial position causing significant shareholder dilution, Show more.

0 Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -61%
1 Megatrend and thematic drivers
Megatrends include Biotechnology & Genomics, Precision Medicine, and Aging Population & Chronic Disease. Themes include Gene Editing & Therapy, Show more.
2 Weak multi-year price returns
2Y Excs Rtn is -34%, 3Y Excs Rtn is -138%
3 Meaningful short interest
Short Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 18%
4 Very low revenue
Rev LTMTotal Revenue or Sales, Last Twelve Months is 0
5 Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -374 Mil
6 Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -115%
7 High stock price volatility
Vol 12M is 1699%
8 Key risks
VOR key risks include [1] a distressed financial position causing significant shareholder dilution, Show more.

VOR in ETFs

Weight = VOR's share of each fund

VTI0.00%
ITOT0.00%
IWM0.03%
XBI0.31%
IWO0.03%
IWN0.02%
VHT0.00%
ONEQ0.00%
+1 more covered ETF

Valuation & Metrics

Price Chart

Why The Stock Moved

Qualitative Assessment

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Updated on 7/13/2026

Vor Biopharma (VOR) stock has gained about 5% since 3/31/2026 because of the following key factors:

1. Mixed Fiscal Q1 2026 Financial Results and Market Reaction.

Vor Biopharma reported a substantial net loss of $219.6 million for fiscal Q1 2026 (ended March 31, 2026), significantly wider than the $32.5 million net loss in fiscal Q1 2025, primarily due to a change in the fair value of liability-classified warrants. The company's reported Q1 2026 net loss per share of -$5.11 also significantly missed the consensus estimate of -$0.79, representing a negative surprise of 548.31%. Despite this significant financial miss, the stock notably rose by 7.84% to 6.45% following the earnings announcement, indicating investors focused more on operational advancements rather than near-term financial results.

2. Steady Progress in Global Phase 3 Trials and Strong Cash Runway.

The company continued to advance its two global Phase 3 UPSTREAM trials for telitacicept in generalized myasthenia gravis (gMG) and primary Sjögren's disease (SjD), with enrollment proceeding as planned. Topline data for the gMG trial is anticipated in the first half of fiscal 2027. Financially, Vor Biopharma maintained a solid cash position of $491.5 million as of March 31, 2026, which is projected to fund operations into early fiscal 2029, alleviating immediate capital concerns.

Show more
Updated on 7/13/2026

Vor Biopharma (VOR) stock has gained about 5% since 3/31/2026 because of the following key factors:

1. Mixed Fiscal Q1 2026 Financial Results and Market Reaction.

Vor Biopharma reported a substantial net loss of $219.6 million for fiscal Q1 2026 (ended March 31, 2026), significantly wider than the $32.5 million net loss in fiscal Q1 2025, primarily due to a change in the fair value of liability-classified warrants. The company's reported Q1 2026 net loss per share of -$5.11 also significantly missed the consensus estimate of -$0.79, representing a negative surprise of 548.31%. Despite this significant financial miss, the stock notably rose by 7.84% to 6.45% following the earnings announcement, indicating investors focused more on operational advancements rather than near-term financial results.

2. Steady Progress in Global Phase 3 Trials and Strong Cash Runway.

The company continued to advance its two global Phase 3 UPSTREAM trials for telitacicept in generalized myasthenia gravis (gMG) and primary Sjögren's disease (SjD), with enrollment proceeding as planned. Topline data for the gMG trial is anticipated in the first half of fiscal 2027. Financially, Vor Biopharma maintained a solid cash position of $491.5 million as of March 31, 2026, which is projected to fund operations into early fiscal 2029, alleviating immediate capital concerns.

3. Positive Clinical Validation from China Approvals for Telitacicept.

Telitacicept, Vor Biopharma's lead asset, received multiple approvals in China for various autoimmune indications, including conditional approval for IgA nephropathy in June 2026 through its partner RemeGen Co., Ltd. The Phase 3 TELIGAN trial results in IgA nephropathy, published in The New England Journal of Medicine, demonstrated a 55.0% relative reduction in proteinuria compared with placebo. This series of regulatory successes in China provided external validation for telitacicept's mechanism and potential, offsetting some domestic financial concerns.

4. Significant Insider Selling Activity.

During the period, there was notable insider selling. Ra Capital Management, L.P., a director, executed multiple sales in April 2026 that exceeded the $5 million threshold. This included selling 458,411 shares at an average price of $16.28 for a total value of approximately $7.46 million on April 17, 2026, and 530,610 shares at an average price of $16.15 for approximately $8.57 million on April 13, 2026. Overall, insiders were net sellers, with total reported sales of over $16 million in the ninety days prior to July 13, 2026, which may have exerted downward pressure or capped upward movement.

5. Analyst Consensus for Long-Term Potential Amidst Awaiting Key Data Readouts.

Analyst ratings generally remained positive, with a consensus of "Buy" or "Strong Buy" and an average price target ranging from $26.33 to $40.43, suggesting significant upside potential. However, with the most anticipated global Phase 3 data (gMG) not expected until the first half of fiscal 2027, investors were likely maintaining positions and awaiting these future catalysts, contributing to the stock's consolidation at its current level rather than experiencing a sharp directional move based on short-term news.

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Stock Movement Drivers

Fundamental Drivers

The 3.7% change in VOR stock from 3/31/2026 to 7/14/2026 was primarily driven by a 0.0% change in the company's Total Revenues ($ Mil).
(LTM values as of)33120267142026Change
Stock Price ($)17.8418.503.7%
Change Contribution By: 
Total Revenues ($ Mil)000.0%
P/S Multiple0.0%
Shares Outstanding (Mil)3943-10.0%
Cumulative Contribution0.0%

LTM = Last Twelve Months as of date shown

Market Drivers

3/31/2026 to 7/14/2026
ReturnCorrelation
VOR3.7% 
Market (SPY)15.6%16.5%
Sector (XLV)8.0%24.7%

Fundamental Drivers

The 41.4% change in VOR stock from 12/31/2025 to 7/14/2026 was primarily driven by a 0.0% change in the company's Total Revenues ($ Mil).
(LTM values as of)123120257142026Change
Stock Price ($)13.0818.5041.4%
Change Contribution By: 
Total Revenues ($ Mil)000.0%
P/S Multiple0.0%
Shares Outstanding (Mil)743-84.5%
Cumulative Contribution0.0%

LTM = Last Twelve Months as of date shown

Market Drivers

12/31/2025 to 7/14/2026
ReturnCorrelation
VOR41.4% 
Market (SPY)10.6%17.6%
Sector (XLV)2.7%28.9%

Fundamental Drivers

The -42.9% change in VOR stock from 6/30/2025 to 7/14/2026 was primarily driven by a -85.5% change in the company's Shares Outstanding (Mil).
(LTM values as of)63020257142026Change
Stock Price ($)32.4018.50-42.9%
Change Contribution By: 
Total Revenues ($ Mil)000.0%
P/S Multiple0.0%
Shares Outstanding (Mil)643-85.5%
Cumulative Contribution0.0%

LTM = Last Twelve Months as of date shown

Market Drivers

6/30/2025 to 7/14/2026
ReturnCorrelation
VOR-42.9% 
Market (SPY)22.7%4.2%
Sector (XLV)19.0%-0.2%

Fundamental Drivers

The -70.1% change in VOR stock from 6/30/2023 to 7/14/2026 was primarily driven by a -92.3% change in the company's Shares Outstanding (Mil).
(LTM values as of)63020237142026Change
Stock Price ($)61.8018.50-70.1%
Change Contribution By: 
Total Revenues ($ Mil)000.0%
P/S Multiple0.0%
Shares Outstanding (Mil)343-92.3%
Cumulative Contribution0.0%

LTM = Last Twelve Months as of date shown

Market Drivers

6/30/2023 to 7/14/2026
ReturnCorrelation
VOR-70.1% 
Market (SPY)75.6%3.5%
Sector (XLV)24.9%1.4%

Return vs. Risk

Price Returns Compared

 202120222023202420252026Total [1]
Returns
VOR Return-69%-43%-66%-51%-41%38%-98%
Peers Return-0%-37%-8%9%-2%47%-8%
S&P 500 Return27%-19%24%23%16%10%100%

Monthly Win Rates [3]
VOR Win Rate45%42%33%33%42%57% 
Peers Win Rate46%42%42%45%48%46% 
S&P 500 Win Rate75%42%67%75%67%57% 

Max Drawdowns [4]
VOR Max Drawdown--69%-76%-78%-97%-33% 
Peers Max Drawdown-55%-56%-57%-52%-51%-32% 
S&P 500 Max Drawdown-5%-25%-10%-8%-19%-9% 


[1] Cumulative total returns since the beginning of 2021
[2] Peers: VRTX, VERA, CRSP, ALLO, FATE.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 7/14/2026 (YTD)

How Low Can It Go

EventVORS&P 500
2025 US Tariff Shock
  % Loss-89.3%-18.8%
  % Gain to Breakeven831.9%23.1%
  Time to Breakeven52 days79 days
2024 Yen Carry Trade Unwind
  % Loss-15.3%-7.8%
  % Gain to Breakeven18.0%8.5%
  Time to Breakeven11 days18 days

Compare to VRTX, VERA, CRSP, ALLO, FATE

In The Past

Vor Biopharma's stock fell -89.3% during the 2025 US Tariff Shock. Such a loss loss requires a 831.9% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

EventVORS&P 500
2025 US Tariff Shock
  % Loss-89.3%-18.8%
  % Gain to Breakeven831.9%23.1%
  Time to Breakeven52 days79 days

Compare to VRTX, VERA, CRSP, ALLO, FATE

In The Past

Vor Biopharma's stock fell -89.3% during the 2025 US Tariff Shock. Such a loss loss requires a 831.9% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

About Vor Biopharma (VOR)

Vor Biopharma, Inc. is a clinical-stage biotechnology company dedicated to developing innovative cell therapies for cancer patients. The company specializes in creating engineered hematopoietic stem cells (eHSCs) to provide a novel and targeted treatment approach for various blood cancers, aiming to improve both the effectiveness and safety of existing therapies.

The company's lead product candidate is VOR33, currently undergoing Phase 1/2 clinical trials. VOR33 consists of eHSCs specifically designed to lack the CD33 protein, which is commonly expressed on acute myeloid leukemia (AML) cancer cells. This engineering allows patients to safely receive CD33-targeted therapies, such as CAR-T cells, bispecific antibodies, or antibody-drug conjugates, which can then selectively destroy CD33-expressing cancer cells without harming healthy blood cells derived from the transplanted VOR33 eHSCs.

Vor Biopharma primarily targets patients suffering from acute myeloid leukemia (AML) and other challenging hematological malignancies. By enabling more potent and selective destruction of cancer cells while protecting healthy ones, the company aims to offer transformative treatment options that could lead to better outcomes and reduced side effects for patients with these severe blood cancers. The company also collaborates with Akron BioProducts on the development and manufacturing of cGMP nucleases.

AI Analysis | Feedback

Here are 1-3 brief analogies to describe Vor Biopharma:

  • Like a specialized CRISPR Therapeutics, but instead of correcting disease-causing genes, Vor uses gene editing to make a patient's healthy stem cells resistant to powerful cancer treatments.

  • Vor Biopharma is like the 'Intel Inside' for certain targeted cancer therapies, developing a critical biological component (engineered stem cells) that allows other companies' powerful drugs to safely destroy cancer cells without harming healthy tissue.

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  • VOR33: An engineered hematopoietic stem cell (eHSC) product candidate in clinical trials for treating acute myeloid leukemia (AML) and other hematological malignancies.
  • eHSC Targeted Therapies: A platform for developing therapies, including CAR-Ts, bispecific antibodies, and antibody-drug conjugates, designed to treat blood cancers.

AI Analysis | Feedback

As a clinical-stage biopharmaceutical company, Vor Biopharma (VOR) is currently focused on the research and development of its engineered hematopoietic stem cell (eHSC) therapies, such as VOR33, which is in Phase 1/2 clinical trials. At this stage, the company does not have commercial products available for sale and therefore does not have major customers in the traditional sense. Its activities are centered on clinical development, regulatory processes, and potentially partnerships or licensing agreements in the future once its therapies are approved.

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Major Suppliers:

  • Akron BioProducts (private company)

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Here is the management team for Vor Biopharma (VOR):

Jean-Paul Kress, MD Chief Executive Officer and Chairman

Dr. Kress brings decades of executive leadership experience in the pharmaceutical and biotech industries. He most recently served as Chief Executive Officer of MorphoSys, where he led the development, approval, and commercialization of Monjuvi® (tafasitamab). He also advanced MorphoSys' pipeline through the landmark acquisition of Constellation Pharmaceuticals in 2021, which strengthened MorphoSys' position in oncology innovation and ultimately led to its subsequent acquisition by Novartis in 2024.

Sandy Mahatme Chief Financial Officer, Chief Business Officer

Mr. Mahatme has over 30 years of executive leadership experience in the biopharmaceutical industry, with a strong background in capital markets, business development, global operations, and shareholder value creation. He co-founded National Resilience, Inc., a biomanufacturing company, where he most recently served as President, Chief Operating Officer, and Chief Financial Officer. Before that, he was Executive Vice President, Chief Financial Officer, and Chief Business Officer at Sarepta Therapeutics, where he led capital formation efforts exceeding $3.5 billion. Mr. Mahatme also held senior positions at Celgene Corporation, Pfizer, Inc., and Ernst & Young, LLP. He currently serves on the boards of CRISPR Therapeutics and Idorsia Pharmaceuticals.

Jeremy Sokolove, MD Chief Medical Officer

Dr. Sokolove is the Chief Medical Officer at Vor Biopharma.

Dallan Murray Chief Commercial Officer

Mr. Murray brings more than 25 years of experience leading commercial strategy, global product launches, and customer-facing organizations in biotechnology and pharmaceutical companies. He previously served as Executive Vice President, Chief Customer Officer at Sarepta Therapeutics, where he led the commercial and medical affairs organizations and the international business unit, contributing to approximately $1.8 billion in net product revenue in 2024.

Adi Osovsky, SJD General Counsel

Dr. Osovsky serves as the General Counsel for Vor Biopharma.

AI Analysis | Feedback

Vor Biopharma (VOR) faces significant key risks primarily stemming from its recent strategic transformation and the inherent challenges of clinical-stage biotechnology development.
  1. High Uncertainty Regarding Strategic Transformation and Financial Viability: Vor Biopharma undertook a substantial strategic shift in May 2025, halting its primary engineered hematopoietic stem cell (eHSC) development programs for cancer, including its lead candidates trem-cel (formerly VOR33) and VCAR33. This decision was attributed to disappointing clinical results and a challenging fundraising environment, leading to a significant workforce reduction of approximately 95% and the winding down of clinical and manufacturing operations. Subsequently, the company pivoted by acquiring global rights to telitacicept, an autoimmune therapy already approved in China. This drastic change in strategic direction introduces substantial uncertainty about Vor Biopharma's ability to successfully execute its new multifaceted strategy, secure adequate ongoing funding, and achieve long-term financial viability.
  2. Clinical Development and Regulatory Approval Risk for Product Candidates: Despite some positive Phase 3 data for telitacicept in China, its path to approval in major markets like the U.S. and Europe is not guaranteed. It will require extensive and costly clinical trials and navigating complex regulatory hurdles. Although the company had cited "disappointing clinical results" for its original eHSC programs, some recent information suggests a continued or renewed effort around trem-cel (VOR33) and VCAR-017, potentially moving them into expanded AML cohorts. Any such ongoing or re-initiated eHSC development efforts will face the inherent high failure rates typical of early-stage clinical development, coupled with complex manufacturing and logistical challenges unique to cell and gene therapies.
  3. Intense Competitive Landscape: Vor Biopharma operates in highly competitive therapeutic areas. For its acquired autoimmune therapy, telitacicept, the company will compete against established treatments and numerous other drugs in development targeting multi-billion dollar autoimmune markets. If Vor Biopharma continues to pursue its eHSC platform in oncology, it will face significant competition from other developers of engineered cell therapies, CAR-T treatments, and other therapies for acute myeloid leukemia (AML) and related hematological malignancies. This intense competition could significantly impact market penetration and commercial success, even if therapies achieve regulatory approval.

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AI Analysis | Feedback

Vor Biopharma's main product, VOR33, targets acute myeloid leukemia (AML) and other hematological malignancies. The addressable markets for these therapies are substantial. For **Acute Myeloid Leukemia (AML) Treatment:** The global market for acute myeloid leukemia treatment was estimated at approximately USD 2.6 billion to USD 3.87 billion in 2025. This market is projected to grow to approximately USD 5.1 billion to USD 10.64 billion by 2032-2035. North America is a leading region in the AML treatment market, holding nearly 38.2% of the global market share in 2025. The U.S. market for acute myeloid leukemia treatment significantly dominates the North American market, accounting for 90.9% in 2024. For **Hematological Malignancies (including AML):** The global hematologic malignancies market was valued between USD 65.1 billion and USD 75.47 billion in 2024. It is expected to grow to approximately USD 151.31 billion to USD 169.4 billion by 2032-2035. In the U.S., the hematologic malignancies market was valued at USD 16.48 billion in 2024 and is projected to reach USD 32.60 billion by 2032. North America held the largest share of the hematologic malignancies market in 2024, attributed to its well-developed healthcare infrastructure and high incidence of blood cancer.

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For Vor Biopharma (VOR), the expected drivers of future revenue growth over the next 2-3 years are primarily centered on the advancement and potential commercialization of telitacicept for autoimmune diseases, following a significant strategic pivot by the company in June 2025.

  1. Successful Global Commercialization of Telitacicept for Generalized Myasthenia Gravis (gMG): Vor Biopharma is focused on advancing telitacicept, a novel dual-target fusion protein, through a global Phase 3 clinical trial for generalized myasthenia gravis (gMG) to support potential regulatory approvals and commercialization in key markets such as the United States, Europe, and Japan. This represents the most advanced and direct pathway to generating product revenue for the company.
  2. Expansion of Telitacicept into Additional Autoimmune Indications and Geographies (ex-Greater China): Telitacicept has demonstrated positive Phase 3 results in Sjögren's disease and is already approved in China for systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). Future revenue growth is anticipated from pursuing regulatory approvals and subsequent commercialization of telitacicept for these or other autoimmune conditions in territories outside of Greater China, significantly broadening its market reach and revenue potential.
  3. Milestone Payments and Royalties from the RemeGen Licensing Agreement: Vor Biopharma's licensing agreement with RemeGen for ex-Greater China rights to telitacicept includes potential milestone payments that could reach up to $4 billion, in addition to royalties on future sales. These payments are expected to contribute to the company's revenue as telitacicept progresses through clinical development, achieves regulatory approvals, and is commercialized in the licensed territories.
  4. Strategic Partnerships and Licensing Agreements for the Engineered Hematopoietic Stem Cell (eHSC) Platform: While the company's primary focus has shifted, Vor Biopharma's engineered hematopoietic stem cell (eHSC) platform, including its lead candidate VOR33, remains an asset for potential revenue generation through strategic collaborations. The company aims to pursue co-development, licensing deals, and non-dilutive funding by partnering its eHSC "shield-and-target" approach with oncology innovators developing CAR-Ts, bispecific antibodies, and antibody-drug conjugates.

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Capital Allocation Decisions for Vor Biopharma (VOR)

Share Repurchases

  • Vor Biopharma made minor share repurchases, with a dollar amount of $1.2 million in 2023 and $0.3 million in 2024.

Share Issuance

  • In December 2025, Vor Biopharma raised approximately $150 million through a private placement by selling 13.9 million shares of common stock at $10.81 per share.
  • The company completed an underwritten public offering in November 2025, raising $100 million by selling 10 million shares of common stock at $10.00 per share.
  • In August 2024, Vor Biopharma successfully raised $110 million in a Series C funding round.

Inbound Investments

  • A private placement in December 2025 saw participation from institutional investors including RA Capital Management, Forbion, Frazier Life Sciences, Caligan Partners, Logos Capital, and Venrock Healthcare Capital Partners.
  • The August 2024 Series C funding round was led by 5AM Ventures, Fidelity, SR One, Novartis Venture Fund, and Cormorant Asset Management.
  • As part of a licensing deal for telitacicept in June 2025, Vor Biopharma issued $80 million worth of warrants to a RemeGen subsidiary, granting them a 23% stake in Vor.

Outbound Investments

  • In June 2025, Vor Biopharma made an upfront payment of $45 million to RemeGen to acquire exclusive ex-China rights to telitacicept, an autoimmune asset.

Capital Expenditures

  • Vor Biopharma reported capital expenditures of approximately $0.2 million in 2024 and $1.1 million in 2023.
  • In Q3 2025, the company invested $244,000 in capital expenditures, primarily for funding long-term assets and infrastructure.
  • Capital expenditures for the last 12 months ending in early 2026 were approximately $699,000.

Latest Trefis Analyses

Title
0ARTICLES

Recent Active Movers

Peer Comparisons

Peers to compare with:

Financials

VORVRTXVERACRSPALLOFATEMedian
NameVor Biop.Vertex P.Vera The.CRISPR T.Allogene.Fate The. 
Mkt Price18.50476.3143.1350.461.852.9930.82
Mkt Cap0.8121.03.14.80.40.41.9
Rev LTM012,21801060
Op Inc LTM-3744,662-383-646-188-139-281
FCF LTM-1513,710-294-426-110-108-130
FCF 3Y Avg-1201,977-183-301-178-124-151
CFO LTM-1504,241-293-400-109-103-130
CFO 3Y Avg-1192,401-183-289-178-121-149

Growth & Margins

VORVRTXVERACRSPALLOFATEMedian
NameVor Biop.Vertex P.Vera The.CRISPR T.Allogene.Fate The. 
Rev Chg LTM-10.1%--97.1%--52.6%-52.6%
Rev Chg 3Y Avg-9.9%--5.0%--14.0%-5.0%
Rev Chg Q-7.8%----20.3%-6.2%
QoQ Delta Rev Chg LTM-1.8%----5.0%-1.6%
Op Inc Chg LTM-205.8%1,214.0%-98.4%-36.3%25.8%24.9%-5.7%
Op Inc Chg 3Y Avg-76.0%364.1%-61.7%-16.1%18.9%18.9%1.4%
Op Mgn LTM-38.2%--64,639.5%--2,207.5%-2,207.5%
Op Mgn 3Y Avg-24.1%--22,035.2%--2,296.1%-2,296.1%
QoQ Delta Op Mgn LTM-0.2%---15.0%7.6%
CFO/Rev LTM-34.7%--39,996.4%--1,632.3%-1,632.3%
CFO/Rev 3Y Avg-21.5%--13,643.7%--1,556.1%-1,556.1%
FCF/Rev LTM-30.4%--42,617.6%--1,711.4%-1,711.4%
FCF/Rev 3Y Avg-17.7%--14,519.9%--1,602.6%-1,602.6%

Valuation

VORVRTXVERACRSPALLOFATEMedian
NameVor Biop.Vertex P.Vera The.CRISPR T.Allogene.Fate The. 
Mkt Cap0.8121.03.14.80.40.41.9
P/S-9.9-4,846.7-56.856.8
P/Op Inc-2.126.0-8.0-7.5-2.4-2.6-2.5
P/EBIT-2.123.9-8.5-7.5-2.6-2.6-2.6
P/E-0.927.9-8.4-8.5-2.6-2.8-2.7
P/CFO-5.328.5-10.5-12.1-4.1-3.5-4.7
Total Yield-111.0%3.6%-12.0%-11.7%-39.1%-36.2%-24.1%
Dividend Yield0.0%0.0%0.0%0.0%0.0%0.0%0.0%
FCF Yield 3Y Avg-1,200.2%1.8%-8.3%-7.6%-37.3%-75.9%-22.8%
D/E0.00.00.00.20.20.20.1
Net D/E-0.6-0.0-0.2-0.3-0.4-0.3-0.3

Returns

VORVRTXVERACRSPALLOFATEMedian
NameVor Biop.Vertex P.Vera The.CRISPR T.Allogene.Fate The. 
1M Rtn28.8%7.1%25.9%1.3%-2.6%45.1%16.5%
3M Rtn16.6%7.2%-2.8%-11.3%-18.9%123.1%2.2%
6M Rtn37.1%4.8%-12.2%-10.2%12.8%193.1%8.8%
12M Rtn-61.3%0.8%81.4%-10.6%43.4%162.3%22.1%
3Y Rtn-68.2%35.0%154.6%-11.3%-62.7%-36.8%-24.1%
1M Excs Rtn29.3%5.0%26.2%-1.6%-3.6%49.8%15.6%
3M Excs Rtn6.3%-1.3%-10.9%-17.5%-49.1%118.7%-6.1%
6M Excs Rtn28.5%-5.6%-19.7%-14.6%-0.1%176.5%-2.9%
12M Excs Rtn-83.5%-18.9%60.6%-31.7%24.0%139.5%2.6%
3Y Excs Rtn-137.8%-30.6%98.4%-78.7%-137.4%-108.8%-93.7%

Comparison Analyses

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Financials

Segment Financials

Net Income by Segment
$ Mil20252024
Commercial development of its product candidates-696-117
Total-696-117


Assets by Segment
$ Mil20232022202120202019
Commercial development of its product candidates1982992437610
Total1982992437610


Price Behavior

Price Behavior
Market Price$18.50 
Market Cap ($ Bil)0.8 
First Trading Date02/05/2021 
Distance from 52W High-62.0% 
   50 Days200 Days
DMA Price$15.74$16.61
DMA Trenddownup
Distance from DMA17.5%11.4%
 3M1YR
Volatility79.2%1,702.5%
Downside Capture3.76526.01
Upside Capture66.57301.45
Correlation (SPY)26.6%4.4%
VOR Betas & Captures as of 6/30/2026

 1M2M3M6M1Y3Y
Beta1.941.702.001.195.822.25
Up Beta4.655.444.244.50-2.090.31
Down Beta2.662.611.61-0.48-0.890.51
Up Capture241%109%97%81%1811%863%
Bmk +ve Days11244067140429
Stock +ve Days10182759113326
Down Capture-19%-66%56%30%202%113%
Bmk -ve Days10172358112321
Stock -ve Days11223565134404

[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with VOR
VOR-63.1%1,699.2%0.93-
Sector ETF (XLV)18.7%15.8%0.890.0%
Equity (SPY)21.7%12.6%1.284.2%
Gold (GLD)20.5%27.9%0.654.7%
Commodities (DBC)27.3%18.9%1.14-5.4%
Real Estate (VNQ)13.0%13.9%0.64-4.1%
Bitcoin (BTCUSD)-47.0%42.7%-1.37-1.3%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 5-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with VOR
VOR-45.4%766.8%0.43-
Sector ETF (XLV)5.9%14.9%0.222.2%
Equity (SPY)13.1%17.1%0.593.8%
Gold (GLD)17.2%18.4%0.763.6%
Commodities (DBC)8.6%19.5%0.33-2.2%
Real Estate (VNQ)2.7%18.9%0.040.6%
Bitcoin (BTCUSD)12.8%53.4%0.420.7%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 10-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with VOR
VOR-31.0%738.0%0.40-
Sector ETF (XLV)10.0%16.6%0.492.3%
Equity (SPY)15.4%17.9%0.733.9%
Gold (GLD)11.2%16.1%0.573.6%
Commodities (DBC)6.3%18.0%0.27-2.0%
Real Estate (VNQ)5.0%20.7%0.210.6%
Bitcoin (BTCUSD)57.3%66.2%0.971.1%

Smart multi-asset allocation framework can stack odds in your favor. Learn How

Short Interest

Short Interest: As Of Date6302026
Short Interest: Shares Quantity7.7 Mil
Short Interest: % Change Since 615202630.1%
Average Daily Volume2.1 Mil
Days-to-Cover Short Interest3.8 days
Basic Shares Quantity43.0 Mil
Short % of Basic Shares18.0%

Earnings Returns History

Updated 7/7/2026
Expand for More
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
1/12/20264.7%16.5%2.7%
SUMMARY STATS   
# Positive111
# Negative000
Median Positive4.7%16.5%2.7%
Median Negative   
Max Positive4.7%16.5%2.7%
Max Negative   
Collapse to Preview
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
1/12/20264.7%16.5%2.7%
SUMMARY STATS   
# Positive111
# Negative000
Median Positive4.7%16.5%2.7%
Median Negative   
Max Positive4.7%16.5%2.7%
Max Negative   

SEC Filings

Expand for More
Report DateFiling DateFiling
03/31/202605/13/202610-Q
12/31/202503/30/202610-K
09/30/202511/13/202510-Q
06/30/202508/12/202510-Q
03/31/202505/14/202510-Q
12/31/202403/20/202510-K
09/30/202411/07/202410-Q
06/30/202408/08/202410-Q
03/31/202405/09/202410-Q
12/31/202303/20/202410-K
09/30/202311/07/202310-Q
06/30/202308/10/202310-Q
03/31/202305/11/202310-Q
12/31/202203/23/202310-K
09/30/202211/10/202210-Q
06/30/202208/11/202210-Q
Collapse to Preview
Report DateFiling DateFiling
03/31/202605/13/202610-Q
12/31/202503/30/202610-K
09/30/202511/13/202510-Q
06/30/202508/12/202510-Q
03/31/202505/14/202510-Q
12/31/202403/20/202510-K
09/30/202411/07/202410-Q
06/30/202408/08/202410-Q
03/31/202405/09/202410-Q
12/31/202303/20/202410-K
09/30/202311/07/202310-Q
06/30/202308/10/202310-Q
03/31/202305/11/202310-Q
12/31/202203/23/202310-K
09/30/202211/10/202210-Q
06/30/202208/11/202210-Q
03/31/202205/12/202210-Q
12/31/202103/14/202210-K
09/30/202111/10/202110-Q
06/30/202108/09/202110-Q
03/31/202105/06/202110-Q
12/31/202003/25/202110-K
09/30/202002/08/2021424B4

Insider Activity

Updated 7/9/2026
Expand for More
#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Ra, Capital Management, LPSee footnotesSell424202615.77165,1502,604,41637,881,038Form
2Ra, Capital Management, LPSee footnotesSell421202615.77171,9632,711,85740,485,454Form
3Ra, Capital Management, LPSee footnotesSell421202616.28458,4117,462,93144,594,306Form
4Ra, Capital Management, LPSee footnotesSell415202616.0153,644858,84051,193,880Form
5Ra, Capital Management, LPSee footnotesSell415202615.97153,7352,455,14851,922,670Form
Collapse to Preview
#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Ra, Capital Management, LPSee footnotesSell424202615.77165,1502,604,41637,881,038Form
2Ra, Capital Management, LPSee footnotesSell421202615.77171,9632,711,85740,485,454Form
3Ra, Capital Management, LPSee footnotesSell421202616.28458,4117,462,93144,594,306Form
4Ra, Capital Management, LPSee footnotesSell415202616.0153,644858,84051,193,880Form
5Ra, Capital Management, LPSee footnotesSell415202615.97153,7352,455,14851,922,670Form
6Ra, Capital Management, LPSee footnotesSell415202616.15530,6108,569,35254,990,718Form
7Ra, Capital Management, LPSee footnotesSell410202615.7582813,04161,985,826Form
8Ra, Capital Management, LPSee footnotesSell410202616.59135,2012,242,98565,305,473Form
9Ra, Capital Management, LPSee footnotesSell410202616.48484,1047,977,78667,098,491Form
10Ra, Capital Management, LPSee footnotesSell406202616.59589,2579,777,89875,596,165Form
11Ra, Capital Management, LPSee footnotesSell406202618.23260,0004,741,06693,818,361Form
12Ra, Capital Management, LPSee footnotesSell1030202525.1224,579617,42419,584,858Form
13Ra, Capital Management, LPSee footnotesSell1030202525.22251,5186,343,28420,282,706Form
14Ra, Capital Management, LPSee footnotesSell1030202527.42124,3113,408,23028,945,428Form
15Ra, Capital Management, LPSee footnotesSell1027202528.1290,9412,557,26133,183,287Form
16Ra, Capital Management, LPSee footnotesSell1027202528.0153,3451,494,19335,600,738Form
17Ra, Capital Management, LPSee footnotesSell1027202528.0176,8802,153,40937,094,931Form
18Ra, Capital Management, LPSee footnotesSell1022202528.1125,027703,50939,388,463Form
19Ra, Capital Management, LPSee footnotesSell1022202529.6792,023  Form
20Reprogrammed, Interchange LlcDirectSell1021202530.072006,01535,094,788Form
21Reprogrammed, Interchange LlcDirectSell1021202530.0511,616349,10135,075,710Form
22Reprogrammed, Interchange LlcDirectSell1021202530.2525,717777,98735,658,614Form
23Ra, Capital Management, LPSee footnotesSell1017202529.39260,8597,667,444443,953Form
24Reprogrammed, Interchange LlcDirectSell1017202530.452,02161,54936,681,040Form
25Ra, Capital Management, LPSee footnotesSell1017202529.45151,8034,470,6041,705,746Form
26Reprogrammed, Interchange LlcDirectSell1017202531.9271,6552,287,19538,509,750Form
27Ra, Capital Management, LPSee footnotesSell1017202530.5551,3631,569,3132,530,920Form
28Reprogrammed, Interchange LlcDirectSell1015202530.3233,6681,020,78738,751,515Form
29Reprogrammed, Interchange LlcDirectSell1015202532.4422,006713,78642,549,060Form
30Reprogrammed, Interchange LlcDirectSell1015202530.9740,9831,269,13341,303,937Form
31Reprogrammed, Interchange LlcDirectSell1010202532.0748,8841,567,61144,086,264Form
32Reprogrammed, Interchange LlcDirectSell1010202533.8775,2622,548,75748,212,393Form
33Reprogrammed, Interchange LlcDirectSell1008202533.8427,624934,71150,718,840Form
34Reprogrammed, Interchange LlcDirectSell1008202537.0170,7632,618,78856,494,183Form
35Reprogrammed, Interchange LlcDirectSell1003202537.837,901298,91160,429,379Form
36Reprogrammed, Interchange LlcDirectSell1003202539.8332,4511,292,45763,932,197Form
37Reprogrammed, Interchange LlcDirectSell1003202539.191,40054,87064,183,990Form
38Reprogrammed, Interchange LlcDirectSell91820251.54447,278688,85350,486,340Form
39Reprogrammed, Interchange LlcDirectSell91520251.64400,000656,32054,521,301Form
40Reprogrammed, Interchange LlcDirectSell91520251.75300,000526,23058,987,729Form
41Reprogrammed, Interchange LlcDirectSell91520251.83284,805521,42162,116,274Form
42Reprogrammed, Interchange LlcDirectSell91020251.82350,000635,28562,100,546Form
43Reprogrammed, Interchange LlcDirectSell91020252.00449,226898,63269,140,409Form
44Reprogrammed, Interchange LlcDirectSell91020251.99464,421924,05869,664,407Form
45Reprogrammed, Interchange LlcDirectSell90520251.97400,000787,28069,825,711Form
46Reprogrammed, Interchange LlcDirectSell90520251.93453,016873,64169,188,677Form
47Reprogrammed, Interchange LlcDirectSell90520252.00554,6121,107,06172,518,223Form
48Reprogrammed, Interchange LlcDirectSell82920252.01806,3511,621,97574,193,307Form
49Reprogrammed, Interchange LlcDirectSell82920252.01611,6471,226,53675,581,598Form
50Reprogrammed, Interchange LlcDirectSell82720252.08284,190591,34379,699,977Form
51Reprogrammed, Interchange LlcDirectSell82720252.12387,346819,74081,661,150Form

Investor Activity (13F)

Updated Jul 15, 2026
13F holdings as of Mar 31, 2026 (Q1 2026)

Active managers (13F portfolio over $250M, at least 3 holdings) with a position over $5M that is either over 10% of their portfolio or held in a concentrated book of 50 or fewer total positions. Index/ETF, sovereign, bank and community-bank filers are excluded.

Active ManagerValue% of PortfolioTotal PositionsQoQFiling
FCPM III Services B.V.$73.5 Mil10.2%14ADD +13.8%13F
Great Point Partners LLC$31.2 Mil7.6%39ADD +27.7%13F
TCG Crossover Management, LLC$96.5 Mil2.8%49New13F
Caligan Partners LP$34.3 Mil2.4%24ADD +108.1%13F
Venrock Adviser, LLC$54.3 Mil2.0%33ADD +56.5%13F
Frazier Life Sciences Management, L.P.$45.4 Mil1.2%38Hold13F
Paradigm Biocapital Advisors LP$31.2 Mil0.6%35Hold13F
Active ManagerValue% of PortfolioTotal PositionsQoQFiling
TCG Crossover Management, LLC$96.5 Mil2.8%49New13F
Caligan Partners LP$34.3 Mil2.4%24ADD +108.1%13F
Venrock Adviser, LLC$54.3 Mil2.0%33ADD +56.5%13F
Great Point Partners LLC$31.2 Mil7.6%39ADD +27.7%13F
FCPM III Services B.V.$73.5 Mil10.2%14ADD +13.8%13F
Active Manager
Active ManagerValue% of PortfolioTotal PositionsQoQFiling
TCG Crossover Management, LLC$96.5 Mil2.8%49New13F
FCPM III Services B.V.$73.5 Mil10.2%14ADD +13.8%13F
Venrock Adviser, LLC$54.3 Mil2.0%33ADD +56.5%13F
Frazier Life Sciences Management, L.P.$45.4 Mil1.2%38Hold13F
Caligan Partners LP$34.3 Mil2.4%24ADD +108.1%13F
Great Point Partners LLC$31.2 Mil7.6%39ADD +27.7%13F
Paradigm Biocapital Advisors LP$31.2 Mil0.6%35Hold13F
Core Cache Last Updated: 7/14/2026