Tearsheet

Qiagen (QGEN)


Market Price (12/18/2025): $45.27 | Market Cap: $9.8 Bil
Sector: Health Care | Industry: Life Sciences Tools & Services

Qiagen (QGEN)


Market Price (12/18/2025): $45.27
Market Cap: $9.8 Bil
Sector: Health Care
Industry: Life Sciences Tools & Services

Investment Highlights Why It Matters Which of these 2 stories sounds closer for this stock?

1. Generates cash flow

The stock generated 4% or more of the share price (called cash flow yield), and shows moderate 10-15% or more growth.

2. Riding a trend

Think Tesla during the pandemic of 2020 when EVs were riding a cultural high, or Nvidia in the current AI boom, or even Figma. These companies don’t have enough yield, or, enough growth, or both - however - they are riding a trend. They have momentum. These can be more volatile - they don’t have the floor of strong cash flow


0 Attractive operating margins
Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is 26%
Weak multi-year price returns
2Y Excs Rtn is -34%, 3Y Excs Rtn is -75%
Weak revenue growth
Rev Chg 3Y AvgRevenue Change % averaged over trailing 3 years is -2.1%
1 Attractive cash flow generation
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 32%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 23%
  Key risks
QGEN key risks include [1] navigating specific regulatory hurdles such as IVDR, Show more.
2 Low stock price volatility
Vol 12M is 26%
  
3 Megatrend and thematic drivers
Megatrends include Biotechnology & Genomics, and Precision Medicine. Themes include Advanced Diagnostics, Personalized Diagnostics, Show more.
  
0 Attractive operating margins
Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is 26%
1 Attractive cash flow generation
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 32%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 23%
2 Low stock price volatility
Vol 12M is 26%
3 Megatrend and thematic drivers
Megatrends include Biotechnology & Genomics, and Precision Medicine. Themes include Advanced Diagnostics, Personalized Diagnostics, Show more.
4 Weak multi-year price returns
2Y Excs Rtn is -34%, 3Y Excs Rtn is -75%
5 Weak revenue growth
Rev Chg 3Y AvgRevenue Change % averaged over trailing 3 years is -2.1%
6 Key risks
QGEN key risks include [1] navigating specific regulatory hurdles such as IVDR, Show more.

Valuation, Metrics & Events

QGEN Stock


Why The Stock Moved


Qualitative Assessment

AI Generated Analysis | Feedback

Here are the key points for why Qiagen (QGEN) stock moved by -2.8% from August 31, 2025, to December 18, 2025:

1. Negative Market Reaction Despite Strong Q3 2025 Earnings: Qiagen reported strong third-quarter 2025 results on November 4th/5th, exceeding analyst expectations for both adjusted diluted earnings per share (EPS) and revenue. Despite this positive financial performance, the stock experienced a slight decline in premarket trading.

2. Citigroup Analyst Downgrade in December: On December 11, 2025, Citigroup downgraded Qiagen's stock from a "Buy" to a "Neutral" rating and simultaneously lowered its price target from $55.00 to $50.00. This downgrade from a prominent financial institution likely contributed to negative investor sentiment.

Show more

Stock Movement Drivers

Return vs. Risk


Price Returns Compared

 202020212022202320242025Total [1]
Returns
QGEN Return56%5%-10%-13%6%2%38%
Peers Return40%32%-27%-13%-1%1%17%
S&P 500 Return16%27%-19%24%23%14%108%

Monthly Win Rates [3]
QGEN Win Rate75%50%58%33%58%67% 
Peers Win Rate63%73%37%48%47%50% 
S&P 500 Win Rate58%75%42%67%75%73% 

Max Drawdowns [4]
QGEN Max Drawdown-2%-12%-26%-29%-7%-15% 
Peers Max Drawdown-24%-5%-38%-33%-13%-31% 
S&P 500 Max Drawdown-31%-1%-25%-1%-2%-15% 


[1] Cumulative total returns since the beginning of 2020
[2] Peers: TMO, BIO, ILMN, DHR, A.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2025 data is for the year up to 12/17/2025 (YTD)

How Low Can It Go

Unique KeyEventQGENS&P 500
2022 Inflation Shock2022 Inflation Shock  
2022 Inflation Shock% Loss% Loss-37.4%-25.4%
2022 Inflation Shock% Gain to Breakeven% Gain to Breakeven59.9%34.1%
2022 Inflation ShockTime to BreakevenTime to BreakevenNot Fully Recovered days464 days
2020 Covid Pandemic2020 Covid Pandemic  
2020 Covid Pandemic% Loss% Loss-15.8%-33.9%
2020 Covid Pandemic% Gain to Breakeven% Gain to Breakeven18.8%51.3%
2020 Covid PandemicTime to BreakevenTime to Breakeven83 days148 days
2018 Correction2018 Correction  
2018 Correction% Loss% Loss-38.6%-19.8%
2018 Correction% Gain to Breakeven% Gain to Breakeven62.9%24.7%
2018 CorrectionTime to BreakevenTime to Breakeven45 days120 days
2008 Global Financial Crisis2008 Global Financial Crisis  
2008 Global Financial Crisis% Loss% Loss-45.2%-56.8%
2008 Global Financial Crisis% Gain to Breakeven% Gain to Breakeven82.4%131.3%
2008 Global Financial CrisisTime to BreakevenTime to Breakeven532 days1,480 days

Compare to A, ATEC, CERS, BLLN, BNBX


In The Past

Qiagen's stock fell -37.4% during the 2022 Inflation Shock from a high on 9/2/2021. A -37.4% loss requires a 59.9% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth over time.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

About Qiagen (QGEN)

Better Bets than Qiagen (QGEN)

Trade Ideas

Select past ideas related to QGEN. For more, see Trefis Trade Ideas.

Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
CRL_11142025_Dip_Buyer_FCFYield11142025CRLCharles River Laboratories InternationalDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
16.8%16.8%-3.7%
GDRX_11142025_Dip_Buyer_High_CFO_Margins_ExInd_DE11142025GDRXGoodRxDip BuyDB | CFO/Rev | Low D/EDip Buy with High Cash Flow Margins
Buying dips for companies with significant cash flows from operations and reasonable debt / market cap
-6.4%-6.4%-11.8%
ASTH_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025ASTHAstrana HealthDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
5.2%5.2%-5.5%
SGRY_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025SGRYSurgery PartnersDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
3.4%3.4%-1.4%
TFX_11072025_Dip_Buyer_FCFYield11072025TFXTeleflexDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
14.4%14.4%-5.1%
Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
CRL_11142025_Dip_Buyer_FCFYield11142025CRLCharles River Laboratories InternationalDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
16.8%16.8%-3.7%
GDRX_11142025_Dip_Buyer_High_CFO_Margins_ExInd_DE11142025GDRXGoodRxDip BuyDB | CFO/Rev | Low D/EDip Buy with High Cash Flow Margins
Buying dips for companies with significant cash flows from operations and reasonable debt / market cap
-6.4%-6.4%-11.8%
ASTH_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025ASTHAstrana HealthDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
5.2%5.2%-5.5%
SGRY_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025SGRYSurgery PartnersDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
3.4%3.4%-1.4%
TFX_11072025_Dip_Buyer_FCFYield11072025TFXTeleflexDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
14.4%14.4%-5.1%

Recent Active Movers

Recent Active Movers

More From Trefis

Peer Comparisons for Qiagen

Peers to compare with:

Financials

QGENTMOBIOILMNDHRAMedian
NameQiagen Thermo F.Bio-Rad .Illumina Danaher Agilent . 
Mkt Price45.21562.56301.28129.56222.63136.66179.64
Mkt Cap9.8212.68.119.8158.238.829.3
Rev LTM2,07143,7352,5584,28824,2686,7885,538
Op Inc LTM5408,0512237984,6131,4441,121
FCF LTM4726,1113371,0005,0171,0881,044
FCF 3Y Avg4026,8112615725,6121,308940
CFO LTM6587,6514921,1226,3181,4951,308
CFO 3Y Avg5758,3074267406,8971,6621,201

Growth & Margins

QGENTMOBIOILMNDHRAMedian
NameQiagen Thermo F.Bio-Rad .Illumina Danaher Agilent . 
Rev Chg LTM5.3%3.2%-0.9%-2.3%2.2%4.5%2.7%
Rev Chg 3Y Avg-2.1%-0.3%-3.0%-3.0%-1.9%0.8%-2.0%
Rev Chg Q6.1%4.9%0.5%0.4%4.4%10.1%4.7%
QoQ Delta Rev Chg LTM1.5%1.2%0.1%0.1%1.1%2.4%1.1%
Op Mgn LTM26.1%18.4%8.7%18.6%19.0%21.3%18.8%
Op Mgn 3Y Avg19.2%17.6%11.2%6.6%21.0%21.5%18.4%
QoQ Delta Op Mgn LTM0.4%0.2%-0.0%-0.6%0.6%-0.1%0.1%
CFO/Rev LTM31.8%17.5%19.2%26.2%26.0%22.0%24.0%
CFO/Rev 3Y Avg28.7%19.3%16.3%17.0%30.3%24.6%21.9%
FCF/Rev LTM22.8%14.0%13.2%23.3%20.7%16.0%18.4%
FCF/Rev 3Y Avg20.1%15.8%10.0%13.2%24.7%19.4%17.6%

Valuation

QGENTMOBIOILMNDHRAMedian
NameQiagen Thermo F.Bio-Rad .Illumina Danaher Agilent . 
Mkt Cap9.8212.68.119.8158.238.829.3
P/S4.74.23.03.45.84.94.4
P/EBIT17.921.7-9.514.631.722.219.8
P/E23.927.9-11.220.740.227.525.7
P/CFO14.724.015.413.022.322.418.8
Total Yield4.2%3.6%-9.0%4.8%2.5%4.5%3.9%
Dividend Yield0.0%0.0%0.0%0.0%0.0%0.8%0.0%
FCF Yield 3Y Avg4.1%3.3%3.0%3.4%3.3%3.7%3.4%
D/E0.20.20.20.20.10.10.2
Net D/E0.00.2-0.00.10.10.10.1

Returns

QGENTMOBIOILMNDHRAMedian
NameQiagen Thermo F.Bio-Rad .Illumina Danaher Agilent . 
1M Rtn2.4%-0.7%-0.9%7.9%1.0%-5.4%0.1%
3M Rtn-0.5%19.1%7.5%28.4%15.6%8.1%11.8%
6M Rtn-2.4%43.5%29.9%43.5%14.9%18.8%24.3%
12M Rtn0.2%6.8%-10.8%-9.5%-4.1%1.0%-1.9%
3Y Rtn-5.7%5.8%-26.2%-33.2%-2.9%-6.4%-6.1%
1M Excs Rtn1.7%-1.5%-1.6%7.2%0.3%-6.2%-0.6%
3M Excs Rtn-2.5%15.7%3.8%24.4%12.9%5.9%9.4%
6M Excs Rtn-14.8%31.2%17.5%31.2%2.5%6.4%11.9%
12M Excs Rtn-11.0%-3.9%-21.5%-21.0%-15.7%-12.0%-13.8%
3Y Excs Rtn-74.6%-68.4%-96.4%-104.5%-75.4%-78.5%-77.0%

Financials

Segment Financials

Revenue by Segment

$ Mil20242023202220212020
Diagnostic solutions698661639461466
Sample technologies663797851804548
Polymerase Chain Reaction (PCR) / Nucleic acid amplification300391434364225
Genomics / Next-Generation Sequencing (NGS)239225245166184
Other66688377104
Total1,9652,1422,2521,8701,526


Price Behavior

Short Interest

Short Interest: As Of Date11282025
Short Interest: Shares Quantity5,602,267
Short Interest: % Change Since 11152025-9.1%
Average Daily Volume1,174,629
Days-to-Cover Short Interest4.77
Basic Shares Quantity216,871,000
Short % of Basic Shares2.6%

Returns Analyses

SEC Filings

Expand for More

Report DateFiling DateFiling
9302025110620256-K 9/30/2025
630202582120256-K 6/30/2025
331202551320256-K 3/31/2025
12312024331202520-F 12/31/2024
9302024110820246-K 9/30/2024
630202480220246-K 6/30/2024
331202450120246-K 3/31/2024
12312023311202420-F 12/31/2023
9302023110120236-K 9/30/2023
630202381020236-K 6/30/2023
331202350520236-K 3/31/2023
12312022313202320-F 12/31/2022
9302022110920226-K 9/30/2022
630202272920226-K 6/30/2022
331202242920226-K 3/31/2022
12312021314202220-F 12/31/2021