Here are 1-3 brief analogies for Ocular Therapeutix (OCUL):

• Alcon for sustained-release eye therapies.
• Bausch + Lomb for long-acting eye medications.
• Like a Moderna for eye treatments, specializing in an innovative drug delivery platform.

• DEXTENZA®: An FDA-approved corticosteroid intraocular insert for treating ocular inflammation and pain following ophthalmic surgery and for ocular itching associated with allergic conjunctivitis.
• AXPAXLI™ (axitinib intravitreal implant): An investigational bioresorbable, sustained-release axitinib intravitreal implant currently in clinical trials for the treatment of wet age-related macular degeneration (AMD) and diabetic retinopathy.
• OTX-TIC (travoprost intracameral implant): An investigational bioresorbable, sustained-release travoprost intracameral implant designed to reduce intraocular pressure in patients with primary open-angle glaucoma or ocular hypertension.

Ocular Therapeutix (OCUL) primarily sells its products to other companies, specifically major pharmaceutical wholesale distributors, rather than directly to individuals.

Based on their financial disclosures, the company's major customers, which accounted for a significant majority of their gross product revenues, are:

• AmerisourceBergen Drug Corporation (a subsidiary of AmerisourceBergen Corporation, symbol: ABC)
• Cardinal Health, Inc. (symbol: CAH)
• McKesson Corporation (symbol: MCK)

These distributors then sell Ocular Therapeutix's products, such as DEXTENZA® and ReSure® Sealant, to ophthalmologists, hospitals, and ambulatory surgery centers.

• Evonik Corporation (parent company Evonik Industries AG, FWB: EVK)

Pravin U. Dugel, MD, Executive Chairman, President, and CEO

Dr. Dugel assumed the roles of President and Chief Executive Officer in April 2024, in addition to his position as Executive Chairman of the Board. He previously served as President of Iveric Bio, Inc., Managing Partner of Retinal Consultants of Arizona and the Retinal Research Institute, Clinical Professor at the USC Eye Institute, Keck School of Medicine, University of Southern California, and a Founding Member of Spectra Eye Institute in Sun City, Arizona. Dr. Dugel founded an aviation company, enabling him to travel to Native American Reservations to treat patients with preventable blindness. He has also served on the Boards of Directors for IVERIC Bio and Aerpio Therapeutics.

Donald Notman, Chief Financial Officer and Chief Operating Officer

Mr. Notman has served as Chief Financial Officer of Ocular Therapeutix since September 2017 and was appointed Chief Operating Officer in August 2024. He brings over 20 years of financial operations and senior-level investment banking experience. Prior to Ocular Therapeutix, Mr. Notman was Senior Vice President and Chief Financial Officer of Thrasos Therapeutics Inc., where he oversaw financial operations, business development, and strategic planning, and was responsible for private equity transactions. He also served as Managing Director and Head of Private Capital Markets for Leerink Swann LLC (now Leerink Partners), where he contributed to building the firm's healthcare investment banking capabilities, and held senior investment banking positions with Deutsche Banc Alex. Brown and Alex. Brown & Sons. Earlier in his career, he was Chief Operating Officer of SmartPets, Inc., a venture-backed direct-to-consumer pet supply startup.

Jeffrey S. Heier, MD, Chief Scientific Officer

Dr. Heier serves as Chief Scientific Officer, a role he transitioned into in February 2024. He is also the Director of the Vitreoretinal Service and Director of Retina Research at Ophthalmic Consultants of Boston (OCB). He previously served as Co-President & Medical Director of OCB from 2016-2020. Dr. Heier is a leading retinal clinical researcher, having been a lead investigator on numerous clinical trials, including Phase 3 trials for treatments in macular degeneration and diabetic macular edema, and has served as a Principal Investigator in over 200 clinical trials.

Nadia K. Waheed, MD, MPH, Chief Medical Officer

Dr. Waheed was appointed Chief Medical Officer in April 2024. She brings almost 20 years of experience in ophthalmology and leadership as a retinal surgeon, scientist, clinical researcher, and Board Member. Most recently, she served as Chief Medical and Development Officer at Beacon Therapeutics. Prior to Beacon, Dr. Waheed was Chief Medical Officer and Head of Clinical Development at Gyroscope Therapeutics, where she played an instrumental role in the company's acquisition by Novartis AG. She also served as Director of the Boston Image Reading Center and Consultant at the New England Eye Center, Tufts University School of Medicine.

Sanjay Nayak, MBBS, PhD, Chief Strategy Officer

Dr. Nayak was appointed Chief Strategy Officer in February 2024. He was the founder and fund manager of Sentiv Capital, a biotech-focused private investment fund that invested in public and private biotechnology companies and was known for its in-depth due diligence and investment strategy. Before Sentiv Capital, Dr. Nayak founded and served as Managing Partner at AnalyzeRx LLC, a healthcare consulting practice providing market analytics and competitive strategy to large pharmaceutical and biotechnology companies. His earlier experience includes a role as Director at Strategic Analysis, Healthcare, which was acquired by IMS Health.

Ocular Therapeutix (OCUL) has several main products and pipeline candidates with the following addressable market sizes:

• DEXTENZA® (dexamethasone ophthalmic insert):
  • For ocular inflammation and pain following ophthalmic surgery: The global market for post-operative cataract surgery inflammation treatment is projected to be USD 5.2 billion in 2025 and is expected to reach USD 10.0 billion by 2035.
  • For ocular itching associated with allergic conjunctivitis: The U.S. allergic conjunctivitis market was valued at USD 1.35 billion in 2023, with projections to grow to USD 2.32 billion by 2032. The global allergic conjunctivitis market was valued at USD 3.04 billion in 2023 and is projected to grow to USD 4.96 billion by 2032.
• AXPAXLI™ (also known as OTX-TKI):
  • For wet age-related macular degeneration (wet AMD) and other retinal diseases (targeting the anti-VEGF market): The global anti-VEGF market is estimated to be $15 billion.
• OTX-TIC: null
• OTX-DED: null
• OTX-CSI: null

Ocular Therapeutix (OCUL) is positioned for future revenue growth over the next 2-3 years, primarily driven by the expansion of its commercial product DEXTENZA and the anticipated launch and market penetration of its lead investigational drug, AXPAXLI, across multiple ophthalmic indications.

Here are the key expected drivers of future revenue growth:

1. Continued Growth of DEXTENZA: Although DEXTENZA, an FDA-approved corticosteroid for ocular inflammation and pain following ophthalmic surgery and ocular itching associated with allergic conjunctivitis, has faced a challenging reimbursement environment in 2025, the company has demonstrated sustained unit sales growth. Efforts to drive demand and increased sales to hospital outpatient departments, as evidenced by a 9.7% increase in end-user unit sales and an 8.5% increase in net product revenue in Q3 2025 compared to Q2 2025, are expected to contribute to its continued growth. The company projected full-year 2024 total net revenues for DEXTENZA to be between $62.0 million and $67.0 million.
2. Commercialization of AXPAXLI for Wet Age-Related Macular Degeneration (wAMD): The most significant future revenue driver is the potential approval and launch of AXPAXLI (OTX-TKI) for wAMD. This long-acting intravitreal implant, designed for administration every 6-12 months, aims to offer a less burdensome treatment option compared to existing therapies. Ocular Therapeutix expects topline data from its pivotal SOL-1 superiority trial in Q1 2026 and from the SOL-R non-inferiority trial in H1 2027, with an NDA filing planned shortly after the SOL-R results. A potential superiority label, if achieved, could provide a significant competitive advantage in the wAMD market.
3. Expansion of AXPAXLI into Diabetic Retinopathy (NPDR and DME): Ocular Therapeutix is actively developing AXPAXLI for non-proliferative diabetic retinopathy (NPDR) and diabetic macular edema (DME), targeting a large and underserved patient population. The company has secured a Special Protocol Assessment (SPA) agreement from the FDA for its NPDR trial (HELIOS program), which streamlines the regulatory pathway. Positive Phase 1 HELIOS data, showing 0% NPDR progression at 48 weeks, supports the advancement of this program, with plans to initiate the HELIOS registrational program (Phase 3).
4. Advancements in Earlier-Stage Pipeline Products: Beyond AXPAXLI, Ocular Therapeutix has other pipeline assets that could contribute to longer-term revenue. These include OTX-TIC (travoprost intracameral implant) in a Phase 2 clinical trial for primary open-angle glaucoma or ocular hypertension, and OTX-CSI and OTX-DED for dry eye disease, which have completed Phase 2 clinical trials. Successful development and commercialization of these products would further diversify the company's revenue streams.

Share Issuance

• In October 2025, Ocular Therapeutix completed an underwritten public offering of common stock, generating approximately $475.0 million in gross proceeds and $445 million in net proceeds.
• The proceeds from the October 2025 offering are earmarked to fund the AXPAXLI open-label extension study for wet AMD, Phase 3 trials for non-proliferative diabetic retinopathy, and investments in manufacturing infrastructure.
• The company also had a significant equity issuance of over $316 million in Q1 2024.

Inbound Investments

• Ocular Therapeutix has a license agreement and collaboration with AffaMed Therapeutics Limited for the development and commercialization of DEXTENZA and PAXTRAVA, aiming to broaden its reach.

Capital Expenditures

• A portion of the net proceeds from the October 2025 equity offering is designated for investments in infrastructure, specifically to support manufacturing.
• The company's current cash balance, including funds from the October 2025 offering, is anticipated to cover planned capital expenditure requirements into 2028.