Here are 1-3 brief analogies to describe Lucid Diagnostics (LUCD):

• Exact Sciences for esophageal cancer screening.

• Hologic for esophageal cancer screening.

• EsoGuard Esophageal DNA Test: A molecular diagnostic test that analyzes DNA collected from the esophagus to detect biomarkers associated with Barrett's Esophagus and esophageal cancer.
• EsoCheck Esophageal Cell Collection Device: A minimally invasive, swallowable device used to collect cells from the esophagus for subsequent diagnostic analysis with the EsoGuard test.

Lucid Diagnostics (symbol: LUCD) primarily operates within a business-to-business (B2B) model, providing its diagnostic services and devices to healthcare entities rather than directly to individual consumers.

Given the nature of their business, which focuses on the early detection of esophageal precancer and cancer through products like the EsoGuard® Esophageal DNA Test and EsoCure® Esophageal Cell Collection Device, their major "customers" are typically the organizations that order and utilize these services for patient care.

Major Customer Categories (Business-to-Business):

Lucid Diagnostics sells primarily to other companies and organizations within the healthcare sector. While they do not publicly disclose specific major customer names due to the fragmented nature of the healthcare market and confidentiality, their customer base can be categorized as follows:

• Gastroenterology Practices and Clinics: These are a primary target for Lucid Diagnostics, as gastroenterologists are specialists who manage and treat patients at risk for esophageal diseases, making them key prescribers of the EsoGuard test.
• Primary Care Physician (PCP) Offices: Lucid Diagnostics is also expanding its reach to PCPs, aiming to educate them on the importance of early screening for at-risk patients, thereby making PCP offices a growing customer segment for ordering the diagnostic tests.
• Hospitals and Integrated Delivery Networks (IDNs): While much of their sales strategy focuses on direct physician adoption, larger hospital systems and IDNs may also represent customer opportunities where Lucid's diagnostic tests can be integrated into broader screening and care pathways.

Lucid Diagnostics' strategy involves engaging directly with these healthcare providers to integrate their testing solutions into routine patient care, with the company's CLIA-certified laboratory (LucidDx Labs) performing the actual test processing.

Lishan Aklog, MD Chief Executive Officer

Dr. Lishan Aklog is the Chairman and Chief Executive Officer of Lucid Diagnostics. He also co-founded and serves as Chairman and Chief Executive Officer of Lucid's parent company, PAVmed Inc. (Nasdaq: PAVM), since its inception in 2014. He previously co-founded a medtech holding company that established four medical device companies, and he led one of its portfolio companies which commercialized AngioVac®, one of his life-saving inventions. Dr. Aklog is an inventor on dozens of patents, including life-saving products he and his colleagues have commercialized. Before his entrepreneurial career in life sciences, he had a distinguished career as an innovator in cardiac surgery, holding faculty positions at leading academic medical centers such as Harvard Medical School and Mount Sinai Medical Center.

Dennis McGrath Chief Financial Officer

Dennis McGrath has been Lucid Diagnostics' Executive Vice President and Chief Financial Officer since March 2017. Prior to joining Lucid Diagnostics, Mr. McGrath held several senior leadership roles at PhotoMedex, Inc. (Nasdaq: PHMD), a global manufacturer and distributor of medical device equipment and services, from 2000 to 2017. His positions at PhotoMedex included director, President, and Chief Financial Officer from 2011 to 2017. Before PhotoMedex's reverse merger with Radiancy, Inc. in December 2011, he also served as Chief Executive Officer from 2009 to 2011 and as Vice President of Finance and Chief Financial Officer from 2000 to 2009.

Shaun O'Neil, MBA President & Chief Operating Officer

Shaun O'Neil has served as Lucid Diagnostics' President & Chief Operating Officer since November 2023. Before this role, he was the company's Chief Commercial Officer. Mr. O'Neil is responsible for leading strategic initiatives at Lucid Diagnostics, including the design and launch of commercial operations, sales and marketing strategy, market access, and the management of Lucid's CLIA-certified laboratory, Lucid Dx Labs.

Brian deGuzman, MD Chief Technology and Compliance Officer

Dr. Brian deGuzman has been the Chief Technology Officer of Lucid Diagnostics since April 2023 and Chief Compliance Officer since January 2022. He previously held the position of Chief Medical Officer from October 2014 until April 2023. Dr. deGuzman, along with Dr. Lishan Aklog, transitioned from practicing medicine to pursue entrepreneurship full-time, founding PAVmed in 2012 as a vehicle for their ventures. He currently oversees technology, compliance, and regulatory aspects for the company.

Michael Gordon General Counsel and Secretary

Michael Gordon has served as General Counsel and Secretary of Lucid Diagnostics since May 2022. Prior to joining Lucid, he was a partner in the corporate department of the law firm Friedman Kaplan Seiler & Adelman LLP from January 2013 to May 2022, and a member of the firm's management committee from January 2019 to May 2022. During his time at Friedman Kaplan, Mr. Gordon represented PAVmed and Lucid in various M&A, financing, and other corporate and commercial transactions, and advised their boards on corporate governance matters.

Lucid Diagnostics' primary product, the EsoGuard Esophageal DNA Test, has an addressable market estimated to be approximately $60 billion in the U.S.. This market is based on an estimated 30 million at-risk patients suffering from chronic gastroesophageal reflux disease (GERD).

Furthermore, an NCI-sponsored study suggests that the addressable market could expand by up to 70% by including at-risk patients who do not present with GERD symptoms.

• Growth in EsoGuard Test Volume: Lucid Diagnostics has demonstrated consistent growth in the volume of EsoGuard tests performed. The company reported a record 4,042 EsoGuard tests in Q4 2024, representing an 84% year-over-year growth and a 45% sequential increase from Q3 2024. This growth trend continued into Q2 2025, with revenue climbing 40% sequentially. The ongoing commercialization efforts for EsoGuard are expected to sustain this increase in test adoption.
• Expansion of Commercial Revenue Channels: The company is strategically diversifying its revenue streams for EsoGuard. It is focusing on a three-pronged approach that includes traditional claims submissions to insurance, direct contracting with employers and self-insured entities, and implementing a new cash-pay program specifically for concierge medicine practices. This multi-channel strategy aims to enhance monetization and expand accessibility.
• Achievement of Medicare Coverage: Securing Medicare coverage for EsoGuard is identified as a critical catalyst for significant market expansion and is expected to drive broader adoption by private insurers. A Medicare Contractor Advisory Committee (CAC) meeting was held in September 2025, and Lucid Diagnostics anticipates a draft Local Coverage Determination by the end of 2025, with potential final coverage in early 2026.
• Expanded Indication for EsoGuard: A National Cancer Institute (NCI)-sponsored study, published in the American Journal of Gastroenterology, has shown that EsoGuard effectively detects esophageal precancer in at-risk patients even without GERD symptoms. This evidence supports an expanded indication for the test, which could potentially increase its total addressable market opportunity by up to 70%, significantly broadening the patient population that could benefit from EsoGuard testing.

Share Issuance

• In 2025, Lucid Diagnostics completed multiple offerings, including a public offering in September that generated approximately $26.9 million in net proceeds from 28,750,000 common shares at $1.00 each, another public offering in April that raised about $16.1 million in net proceeds from 14,375,000 shares at $1.20 each, and a registered direct offering in March resulting in $15.3 million in gross proceeds from 13,939,331 shares at $1.10 each.
• In October 2023, the company sold 5,000 shares of Series A-1 Preferred Stock to accredited investors, generating aggregate gross proceeds of $5.0 million.
• Lucid Diagnostics completed its Initial Public Offering (IPO) in October 2021, which involved offering up to 5,000,000 shares of common stock.

Inbound Investments

• PAVmed Inc. holds a controlling financial interest in Lucid Diagnostics, owning approximately 70.1% as of December 31, 2023, and 64.9% as of March 21, 2024, of the combined voting power of outstanding common stock.
• Lucid Diagnostics relies on PAVmed for various critical services, including management, technical, research and development, legal, accounting, and administrative support.
• The company received $5.0 million in gross proceeds from the sale of Series A-1 Preferred Stock to accredited investors in October 2023.