NeoGenomics (NEO)
Market Price (12/22/2025): $11.9 | Market Cap: $1.5 BilSector: Health Care | Industry: Health Care Services
NeoGenomics (NEO)
Market Price (12/22/2025): $11.9Market Cap: $1.5 BilSector: Health CareIndustry: Health Care Services
Investment Highlights
Why It Matters
Which of these 2 stories sounds closer for this stock?
1. Generates cash flow
The stock generated 4% or more of the share price (called cash flow yield), and shows moderate 10-15% or more growth.
2. Riding a trend
Think Tesla during the pandemic of 2020 when EVs were riding a cultural high, or Nvidia in the current AI boom, or even Figma. These companies don’t have enough yield, or, enough growth, or both - however - they are riding a trend. They have momentum. These can be more volatile - they don’t have the floor of strong cash flow
| Megatrend and thematic driversMegatrends include Biotechnology & Genomics, Precision Medicine, and Aging Population & Chronic Disease. Themes include Advanced Diagnostics, Show more. | Weak multi-year price returns2Y Excs Rtn is -85%, 3Y Excs Rtn is -65% | Not profitable at operating income levelOp Inc LTMOperating Income, Last Twelve Months is -92 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -13% |
| Expensive valuation multiplesP/CFOPrice/(Cash Flow from Operations). CFO is cash before capital expenditures. is 111x | ||
| Not cash flow generativeFCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -2.4% | ||
| Yield minus risk free rate is negativeERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -12% | ||
| Key risksNEO key risks include [1] persistent unprofitability and declining margins, Show more. |
| Megatrend and thematic driversMegatrends include Biotechnology & Genomics, Precision Medicine, and Aging Population & Chronic Disease. Themes include Advanced Diagnostics, Show more. |
| Weak multi-year price returns2Y Excs Rtn is -85%, 3Y Excs Rtn is -65% |
| Not profitable at operating income levelOp Inc LTMOperating Income, Last Twelve Months is -92 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -13% |
| Expensive valuation multiplesP/CFOPrice/(Cash Flow from Operations). CFO is cash before capital expenditures. is 111x |
| Not cash flow generativeFCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -2.4% |
| Yield minus risk free rate is negativeERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -12% |
| Key risksNEO key risks include [1] persistent unprofitability and declining margins, Show more. |
Valuation, Metrics & Events
NEO Stock
Why The Stock Moved
Qualitative Assessment
AI Generated Analysis | Feedback
Here are the key points explaining NeoGenomics' (NEO) stock movement for the approximate time period from August 31, 2025, to December 22, 2025:
1. Favorable Patent Litigation Outcomes
NeoGenomics experienced significant positive developments regarding its patent litigation. On August 29, 2025, a court ruled in favor of NeoGenomics in a patent infringement lawsuit against Natera, which was a crucial step for the full clinical launch of its RaDaR ST MRD assay. This positive momentum continued when Natera voluntarily withdrew its appeal in the ongoing RaDaR patent litigation on December 15, 2025, further solidifying NeoGenomics' position and market access for this key diagnostic tool.
2. Strong Q3 2025 Clinical Revenue Growth
On October 28, 2025, NeoGenomics reported robust third-quarter 2025 results. The company's total revenue increased by 12% year-over-year to $188 million, largely driven by an 18% growth in clinical revenue. Notably, Next-Generation Sequencing (NGS) revenue saw a 24% year-over-year increase, now contributing to nearly one-third of the total clinical revenue, indicating strong performance in a high-growth segment.
Stock Movement Drivers
Return vs. Risk
Price Returns Compared
| 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total [1] | |
|---|---|---|---|---|---|---|---|
| Returns | |||||||
| NEO Return | 84% | -37% | -73% | 75% | 2% | -29% | -60% |
| Peers Return | 23% | 16% | -38% | 13% | -5% | 55% | 48% |
| S&P 500 Return | 16% | 27% | -19% | 24% | 23% | 16% | 112% |
Monthly Win Rates [3] | |||||||
| NEO Win Rate | 58% | 33% | 17% | 58% | 42% | 42% | |
| Peers Win Rate | 63% | 55% | 35% | 47% | 48% | 55% | |
| S&P 500 Win Rate | 58% | 75% | 42% | 67% | 75% | 73% | |
Max Drawdowns [4] | |||||||
| NEO Max Drawdown | -30% | -43% | -81% | -2% | -20% | -71% | |
| Peers Max Drawdown | -43% | -16% | -49% | -14% | -28% | -21% | |
| S&P 500 Max Drawdown | -31% | -1% | -25% | -1% | -2% | -15% | |
[1] Cumulative total returns since the beginning of 2020
[2] Peers: LH, DGX, EXAS, GH, MYGN. See NEO Returns vs. Peers.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2025 data is for the year up to 12/19/2025 (YTD)
How Low Can It Go
| Event | NEO | S&P 500 |
|---|---|---|
| 2022 Inflation Shock | ||
| % Loss | -89.2% | -25.4% |
| % Gain to Breakeven | 828.4% | 34.1% |
| Time to Breakeven | Not Fully Recovered days | 464 days |
| 2020 Covid Pandemic | ||
| % Loss | -40.6% | -33.9% |
| % Gain to Breakeven | 68.4% | 51.3% |
| Time to Breakeven | 112 days | 148 days |
| 2018 Correction | ||
| % Loss | -39.2% | -19.8% |
| % Gain to Breakeven | 64.6% | 24.7% |
| Time to Breakeven | 59 days | 120 days |
| 2008 Global Financial Crisis | ||
| % Loss | -69.9% | -56.8% |
| % Gain to Breakeven | 232.1% | 131.3% |
| Time to Breakeven | 209 days | 1,480 days |
Compare to TMO, A, IQV, MTD, BIO
In The Past
NeoGenomics's stock fell -89.2% during the 2022 Inflation Shock from a high on 2/12/2021. A -89.2% loss requires a 828.4% gain to breakeven.
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Asset Allocation
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Latest Trefis Analyses
| Title | Topic | Date | |
|---|---|---|---|
| DASHBOARDS | |||
| NeoGenomics Earnings Notes | |||
| NeoGenomics Stock Jump Looks Great, But How Secure Is That Gain? | Return | ||
| Day 5 of Gains Streak for NeoGenomics Stock with 37% Return (vs. -47% YTD) [9/2/2025] | Notification | ||
| NeoGenomics (NEO) Operating Cash Flow Comparison | Financials | ||
| NeoGenomics (NEO) Net Income Comparison | Financials | ||
| NeoGenomics (NEO) EBITDA Comparison | Financials | ||
| NeoGenomics (NEO) Revenue Comparison | Financials | ||
| NeoGenomics (NEO) Debt Comparison | Financials | ||
| NeoGenomics (NEO) Tax Expense Comparison | Financials | ||
| NeoGenomics (NEO) Operating Income Comparison | Financials | ||
| ARTICLES | |||
| NEO Stock Up 37% after 5-Day Win Streak | September 2nd, 2025 | ||
| Market Movers | Winners: WOOF, NEO, AMBA | Losers: MRVL, UP, AEVA | August 29th, 2025 |
Trade Ideas
Select past ideas related to NEO. For more, see Trefis Trade Ideas.
| Date | Ticker | Company | Category | Trade Strategy | 6M Fwd Rtn | 12M Fwd Rtn | 12M Max DD |
|---|---|---|---|---|---|---|---|
| 11142025 | CRL | Charles River Laboratories International | Dip Buy | DB | FCFY OPMDip Buy with High FCF Yield and High MarginBuying dips for companies with high FCF yield and meaningfully high operating margin | 17.4% | 17.4% | -3.7% |
| 11142025 | GDRX | GoodRx | Dip Buy | DB | CFO/Rev | Low D/EDip Buy with High Cash Flow MarginsBuying dips for companies with significant cash flows from operations and reasonable debt / market cap | -6.7% | -6.7% | -11.8% |
| 11142025 | ASTH | Astrana Health | Dip Buy | DB | FCF Yield | Low D/EDip Buy with High Free Cash Flow YieldBuying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap | 10.9% | 10.9% | -5.5% |
| 11142025 | SGRY | Surgery Partners | Dip Buy | DB | FCF Yield | Low D/EDip Buy with High Free Cash Flow YieldBuying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap | 2.7% | 2.7% | -1.4% |
| 11072025 | TFX | Teleflex | Dip Buy | DB | FCFY OPMDip Buy with High FCF Yield and High MarginBuying dips for companies with high FCF yield and meaningfully high operating margin | 11.4% | 11.4% | -5.1% |
| Date | Ticker | Company | Category | Trade Strategy | 6M Fwd Rtn | 12M Fwd Rtn | 12M Max DD |
|---|---|---|---|---|---|---|---|
| 11142025 | CRL | Charles River Laboratories International | Dip Buy | DB | FCFY OPMDip Buy with High FCF Yield and High MarginBuying dips for companies with high FCF yield and meaningfully high operating margin | 17.4% | 17.4% | -3.7% |
| 11142025 | GDRX | GoodRx | Dip Buy | DB | CFO/Rev | Low D/EDip Buy with High Cash Flow MarginsBuying dips for companies with significant cash flows from operations and reasonable debt / market cap | -6.7% | -6.7% | -11.8% |
| 11142025 | ASTH | Astrana Health | Dip Buy | DB | FCF Yield | Low D/EDip Buy with High Free Cash Flow YieldBuying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap | 10.9% | 10.9% | -5.5% |
| 11142025 | SGRY | Surgery Partners | Dip Buy | DB | FCF Yield | Low D/EDip Buy with High Free Cash Flow YieldBuying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap | 2.7% | 2.7% | -1.4% |
| 11072025 | TFX | Teleflex | Dip Buy | DB | FCFY OPMDip Buy with High FCF Yield and High MarginBuying dips for companies with high FCF yield and meaningfully high operating margin | 11.4% | 11.4% | -5.1% |
Research & Analysis
Invest in Strategies
Wealth Management
Peer Comparisons for NeoGenomics
| Peers to compare with: |
Financials
| Median | |
|---|---|
| Name | |
| Mkt Price | 100.78 |
| Mkt Cap | 15.9 |
| Rev LTM | 1,992 |
| Op Inc LTM | -87 |
| FCF LTM | 115 |
| FCF 3Y Avg | 39 |
| CFO LTM | 200 |
| CFO 3Y Avg | 127 |
Growth & Margins
| Median | |
|---|---|
| Name | |
| Rev Chg LTM | 11.9% |
| Rev Chg 3Y Avg | 10.6% |
| Rev Chg Q | 12.5% |
| QoQ Delta Rev Chg LTM | 3.0% |
| Op Mgn LTM | -7.5% |
| Op Mgn 3Y Avg | -11.3% |
| QoQ Delta Op Mgn LTM | 0.3% |
| CFO/Rev LTM | 7.2% |
| CFO/Rev 3Y Avg | 4.5% |
| FCF/Rev LTM | 2.8% |
| FCF/Rev 3Y Avg | -0.6% |
Valuation
| Median | |
|---|---|
| Name | |
| Mkt Cap | 15.9 |
| P/S | 2.0 |
| P/EBIT | -7.7 |
| P/E | -7.5 |
| P/CFO | 11.0 |
| Total Yield | -4.2% |
| Dividend Yield | 0.0% |
| FCF Yield 3Y Avg | -0.5% |
| D/E | 0.3 |
| Net D/E | 0.1 |
Returns
| Median | |
|---|---|
| Name | |
| 1M Rtn | -5.1% |
| 3M Rtn | 17.6% |
| 6M Rtn | 51.1% |
| 12M Rtn | 14.3% |
| 3Y Rtn | 22.2% |
| 1M Excs Rtn | -1.9% |
| 3M Excs Rtn | 16.2% |
| 6M Excs Rtn | 38.3% |
| 12M Excs Rtn | -0.1% |
| 3Y Excs Rtn | -53.4% |
Comparison Analyses
Segment Financials
Revenue by Segment
| $ Mil | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|
| Single Segment | 592 | ||||
| Advanced Diagnostics | 91 | 80 | 62 | 48 | |
| Clinical Services | 419 | 404 | 382 | 361 | |
| Total | 592 | 510 | 484 | 444 | 409 |
| $ Mil | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|
| Single Segment | -108 | ||||
| Total | -108 |
| $ Mil | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|
| Single Segment | -88 | ||||
| Total | -88 |
Returns Analyses
Earnings Returns History
Expand for More| Forward Returns | |||
|---|---|---|---|
| Earnings Date | 1D Returns | 5D Returns | 21D Returns |
| 10/28/2025 | -2.4% | -3.7% | 21.5% |
| 7/29/2025 | -18.7% | -12.2% | 3.7% |
| 4/29/2025 | -34.0% | -21.4% | -25.6% |
| 2/18/2025 | -14.0% | -22.5% | -33.4% |
| 11/5/2024 | 5.6% | 15.6% | 27.4% |
| 7/29/2024 | 18.0% | 10.7% | 12.0% |
| 4/30/2024 | -8.5% | 1.9% | -9.1% |
| 2/20/2024 | 12.1% | 9.7% | 5.7% |
| ... | |||
| SUMMARY STATS | |||
| # Positive | 9 | 12 | 13 |
| # Negative | 13 | 10 | 9 |
| Median Positive | 14.2% | 11.6% | 12.0% |
| Median Negative | -8.3% | -11.0% | -10.0% |
| Max Positive | 25.4% | 54.2% | 63.1% |
| Max Negative | -34.0% | -22.5% | -34.5% |
SEC Filings
Expand for More| Report Date | Filing Date | Filing |
|---|---|---|
| 9302025 | 10282025 | 10-Q 9/30/2025 |
| 6302025 | 7292025 | 10-Q 6/30/2025 |
| 3312025 | 4292025 | 10-Q 3/31/2025 |
| 12312024 | 2182025 | 10-K 12/31/2024 |
| 9302024 | 11052024 | 10-Q 9/30/2024 |
| 6302024 | 7302024 | 10-Q 6/30/2024 |
| 3312024 | 4302024 | 10-Q 3/31/2024 |
| 12312023 | 2202024 | 10-K 12/31/2023 |
| 9302023 | 11062023 | 10-Q 9/30/2023 |
| 6302023 | 8082023 | 10-Q 6/30/2023 |
| 3312023 | 5092023 | 10-Q 3/31/2023 |
| 12312022 | 2242023 | 10-K 12/31/2022 |
| 9302022 | 11082022 | 10-Q 9/30/2022 |
| 6302022 | 8092022 | 10-Q 6/30/2022 |
| 3312022 | 5092022 | 10-Q 3/31/2022 |
| 12312021 | 2252022 | 10-K 12/31/2021 |
External Quote Links
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