Tearsheet

Investment Highlights Why It Matters Which of these 2 stories sounds closer for this stock?

1. Generates cash flow

The stock generated 4% or more of the share price (called cash flow yield), and shows moderate 10-15% or more growth.

2. Riding a trend

Think Tesla during the pandemic of 2020 when EVs were riding a cultural high, or Nvidia in the current AI boom, or even Figma. These companies don’t have enough yield, or, enough growth, or both - however - they are riding a trend. They have momentum. These can be more volatile - they don’t have the floor of strong cash flow


0 Megatrend and thematic drivers
Megatrends include Biotechnology & Genomics, Precision Medicine, and Aging Population & Chronic Disease. Themes include Advanced Diagnostics, Show more.
Weak multi-year price returns
2Y Excs Rtn is -85%, 3Y Excs Rtn is -65%
Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -92 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -13%
1   Expensive valuation multiples
P/CFOPrice/(Cash Flow from Operations). CFO is cash before capital expenditures. is 111x
2   Not cash flow generative
FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -2.4%
3   Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -12%
4   Key risks
NEO key risks include [1] persistent unprofitability and declining margins, Show more.
0 Megatrend and thematic drivers
Megatrends include Biotechnology & Genomics, Precision Medicine, and Aging Population & Chronic Disease. Themes include Advanced Diagnostics, Show more.
1 Weak multi-year price returns
2Y Excs Rtn is -85%, 3Y Excs Rtn is -65%
2 Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -92 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -13%
3 Expensive valuation multiples
P/CFOPrice/(Cash Flow from Operations). CFO is cash before capital expenditures. is 111x
4 Not cash flow generative
FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -2.4%
5 Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -12%
6 Key risks
NEO key risks include [1] persistent unprofitability and declining margins, Show more.

Valuation, Metrics & Events

NEO Stock


Why The Stock Moved


Qualitative Assessment

AI Generated Analysis | Feedback

Here are the key points explaining NeoGenomics' (NEO) stock movement for the approximate time period from August 31, 2025, to December 22, 2025:

1. Favorable Patent Litigation Outcomes
NeoGenomics experienced significant positive developments regarding its patent litigation. On August 29, 2025, a court ruled in favor of NeoGenomics in a patent infringement lawsuit against Natera, which was a crucial step for the full clinical launch of its RaDaR ST MRD assay. This positive momentum continued when Natera voluntarily withdrew its appeal in the ongoing RaDaR patent litigation on December 15, 2025, further solidifying NeoGenomics' position and market access for this key diagnostic tool.

2. Strong Q3 2025 Clinical Revenue Growth
On October 28, 2025, NeoGenomics reported robust third-quarter 2025 results. The company's total revenue increased by 12% year-over-year to $188 million, largely driven by an 18% growth in clinical revenue. Notably, Next-Generation Sequencing (NGS) revenue saw a 24% year-over-year increase, now contributing to nearly one-third of the total clinical revenue, indicating strong performance in a high-growth segment.

Show more

Stock Movement Drivers

Return vs. Risk


Price Returns Compared

 202020212022202320242025Total [1]
Returns
NEO Return84%-37%-73%75%2%-29%-60%
Peers Return23%16%-38%13%-5%55%48%
S&P 500 Return16%27%-19%24%23%16%112%

Monthly Win Rates [3]
NEO Win Rate58%33%17%58%42%42% 
Peers Win Rate63%55%35%47%48%55% 
S&P 500 Win Rate58%75%42%67%75%73% 

Max Drawdowns [4]
NEO Max Drawdown-30%-43%-81%-2%-20%-71% 
Peers Max Drawdown-43%-16%-49%-14%-28%-21% 
S&P 500 Max Drawdown-31%-1%-25%-1%-2%-15% 


[1] Cumulative total returns since the beginning of 2020
[2] Peers: LH, DGX, EXAS, GH, MYGN. See NEO Returns vs. Peers.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2025 data is for the year up to 12/19/2025 (YTD)

How Low Can It Go

Unique KeyEventNEOS&P 500
2022 Inflation Shock2022 Inflation Shock  
2022 Inflation Shock% Loss% Loss-89.2%-25.4%
2022 Inflation Shock% Gain to Breakeven% Gain to Breakeven828.4%34.1%
2022 Inflation ShockTime to BreakevenTime to BreakevenNot Fully Recovered days464 days
2020 Covid Pandemic2020 Covid Pandemic  
2020 Covid Pandemic% Loss% Loss-40.6%-33.9%
2020 Covid Pandemic% Gain to Breakeven% Gain to Breakeven68.4%51.3%
2020 Covid PandemicTime to BreakevenTime to Breakeven112 days148 days
2018 Correction2018 Correction  
2018 Correction% Loss% Loss-39.2%-19.8%
2018 Correction% Gain to Breakeven% Gain to Breakeven64.6%24.7%
2018 CorrectionTime to BreakevenTime to Breakeven59 days120 days
2008 Global Financial Crisis2008 Global Financial Crisis  
2008 Global Financial Crisis% Loss% Loss-69.9%-56.8%
2008 Global Financial Crisis% Gain to Breakeven% Gain to Breakeven232.1%131.3%
2008 Global Financial CrisisTime to BreakevenTime to Breakeven209 days1,480 days

Compare to TMO, A, IQV, MTD, BIO


In The Past

NeoGenomics's stock fell -89.2% during the 2022 Inflation Shock from a high on 2/12/2021. A -89.2% loss requires a 828.4% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth over time.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

About NeoGenomics (NEO)

Better Bets than NeoGenomics (NEO)

Trade Ideas

Select past ideas related to NEO. For more, see Trefis Trade Ideas.

Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
CRL_11142025_Dip_Buyer_FCFYield11142025CRLCharles River Laboratories InternationalDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
17.4%17.4%-3.7%
GDRX_11142025_Dip_Buyer_High_CFO_Margins_ExInd_DE11142025GDRXGoodRxDip BuyDB | CFO/Rev | Low D/EDip Buy with High Cash Flow Margins
Buying dips for companies with significant cash flows from operations and reasonable debt / market cap
-6.7%-6.7%-11.8%
ASTH_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025ASTHAstrana HealthDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
10.9%10.9%-5.5%
SGRY_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025SGRYSurgery PartnersDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
2.7%2.7%-1.4%
TFX_11072025_Dip_Buyer_FCFYield11072025TFXTeleflexDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
11.4%11.4%-5.1%
Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
CRL_11142025_Dip_Buyer_FCFYield11142025CRLCharles River Laboratories InternationalDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
17.4%17.4%-3.7%
GDRX_11142025_Dip_Buyer_High_CFO_Margins_ExInd_DE11142025GDRXGoodRxDip BuyDB | CFO/Rev | Low D/EDip Buy with High Cash Flow Margins
Buying dips for companies with significant cash flows from operations and reasonable debt / market cap
-6.7%-6.7%-11.8%
ASTH_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025ASTHAstrana HealthDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
10.9%10.9%-5.5%
SGRY_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025SGRYSurgery PartnersDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
2.7%2.7%-1.4%
TFX_11072025_Dip_Buyer_FCFYield11072025TFXTeleflexDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
11.4%11.4%-5.1%

Recent Active Movers

Recent Active Movers

More From Trefis

Peer Comparisons for NeoGenomics

Peers to compare with:

Financials

NEOLHDGXEXASGHMYGNMedian
NameNeoGenom.Labcorp Quest Di.Exact Sc.Guardant.Myriad G. 
Mkt Price11.83252.03176.06101.8299.746.55100.78
Mkt Cap1.520.919.719.312.40.615.9
Rev LTM70913,76510,8503,0829038251,992
Op Inc LTM-921,3651,531-155-442-82-87
FCF LTM-171,3811,393247-262-30115
FCF 3Y Avg-291,0801,004107-300-9239
CFO LTM141,8041,885387-223-2200
CFO 3Y Avg21,5311,454253-271-45127

Growth & Margins

NEOLHDGXEXASGHMYGNMedian
NameNeoGenom.Labcorp Quest Di.Exact Sc.Guardant.Myriad G. 
Rev Chg LTM10.1%8.3%13.7%14.5%30.4%0.2%11.9%
Rev Chg 3Y Avg12.6%8.6%2.2%15.5%28.0%7.8%10.6%
Rev Chg Q11.9%8.6%13.2%20.0%38.5%-3.6%12.5%
QoQ Delta Rev Chg LTM2.9%2.1%3.1%4.8%8.9%-0.9%3.0%
Op Mgn LTM-13.0%9.9%14.1%-5.0%-49.0%-9.9%-7.5%
Op Mgn 3Y Avg-14.6%9.6%13.1%-7.9%-73.1%-14.7%-11.3%
QoQ Delta Op Mgn LTM0.4%0.8%0.1%0.1%6.6%-0.8%0.3%
CFO/Rev LTM1.9%13.1%17.4%12.6%-24.7%-0.3%7.2%
CFO/Rev 3Y Avg0.1%11.9%14.5%9.0%-41.4%-5.8%4.5%
FCF/Rev LTM-2.4%10.0%12.8%8.0%-29.1%-3.6%2.8%
FCF/Rev 3Y Avg-4.8%8.4%10.0%3.6%-45.5%-11.8%-0.6%

Valuation

NEOLHDGXEXASGHMYGNMedian
NameNeoGenom.Labcorp Quest Di.Exact Sc.Guardant.Myriad G. 
Mkt Cap1.520.919.719.312.40.615.9
P/S2.11.51.86.313.80.72.0
P/EBIT-13.915.712.6-20.0-31.6-1.5-7.7
P/E-13.424.520.3-19.5-31.2-1.5-7.5
P/CFO111.011.610.549.8-55.8-277.211.0
Total Yield-7.5%5.2%6.7%-5.1%-3.2%-65.7%-4.2%
Dividend Yield0.0%1.2%1.8%0.0%0.0%0.0%0.0%
FCF Yield 3Y Avg-2.0%5.4%5.6%1.0%-7.8%-6.4%-0.5%
D/E0.30.30.30.10.10.30.3
Net D/E0.20.30.30.10.10.10.1

Returns

NEOLHDGXEXASGHMYGNMedian
NameNeoGenom.Labcorp Quest Di.Exact Sc.Guardant.Myriad G. 
1M Rtn3.0%-4.9%-7.9%0.9%-5.4%-11.2%-5.1%
3M Rtn38.8%-8.9%-3.7%91.0%68.6%-15.7%17.6%
6M Rtn69.0%-3.3%-1.0%92.0%103.0%33.1%51.1%
12M Rtn-27.9%11.5%17.2%71.4%214.9%-51.0%14.3%
3Y Rtn24.1%11.1%20.2%91.6%229.8%-59.8%22.2%
1M Excs Rtn12.2%-5.9%-8.2%15.3%-2.7%-1.2%-1.9%
3M Excs Rtn38.7%-11.5%-6.4%88.0%64.7%-18.6%16.2%
6M Excs Rtn55.3%-16.4%-14.6%80.4%92.0%21.3%38.3%
12M Excs Rtn-45.5%-2.6%2.4%55.7%173.3%-65.6%-0.1%
3Y Excs Rtn-64.8%-59.5%-47.3%52.5%65.1%-133.7%-53.4%

Financials

Segment Financials

Revenue by Segment

$ Mil20242023202220212020
Single Segment592    
Advanced Diagnostics 91806248
Clinical Services 419404382361
Total592510484444409


Operating Income by Segment
$ Mil20242023202220212020
Single Segment-108    
Total-108    


Net Income by Segment
$ Mil20242023202220212020
Single Segment-88    
Total-88    


Price Behavior

Short Interest

Short Interest: As Of Date11282025
Short Interest: Shares Quantity9,054,876
Short Interest: % Change Since 111520257.6%
Average Daily Volume2,126,986
Days-to-Cover Short Interest4.26
Basic Shares Quantity128,415,000
Short % of Basic Shares7.1%

Earnings Returns History

Expand for More

 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
10/28/2025-2.4%-3.7%21.5%
7/29/2025-18.7%-12.2%3.7%
4/29/2025-34.0%-21.4%-25.6%
2/18/2025-14.0%-22.5%-33.4%
11/5/20245.6%15.6%27.4%
7/29/202418.0%10.7%12.0%
4/30/2024-8.5%1.9%-9.1%
2/20/202412.1%9.7%5.7%
...
SUMMARY STATS   
# Positive91213
# Negative13109
Median Positive14.2%11.6%12.0%
Median Negative-8.3%-11.0%-10.0%
Max Positive25.4%54.2%63.1%
Max Negative-34.0%-22.5%-34.5%

SEC Filings

Expand for More

Report DateFiling DateFiling
93020251028202510-Q 9/30/2025
6302025729202510-Q 6/30/2025
3312025429202510-Q 3/31/2025
12312024218202510-K 12/31/2024
93020241105202410-Q 9/30/2024
6302024730202410-Q 6/30/2024
3312024430202410-Q 3/31/2024
12312023220202410-K 12/31/2023
93020231106202310-Q 9/30/2023
6302023808202310-Q 6/30/2023
3312023509202310-Q 3/31/2023
12312022224202310-K 12/31/2022
93020221108202210-Q 9/30/2022
6302022809202210-Q 6/30/2022
3312022509202210-Q 3/31/2022
12312021225202210-K 12/31/2021