HeartFlow (HTFL)
Market Price (6/24/2026): $34.56 | Market Cap: $3.0 BilSector: Health Care | Industry: Health Care Technology
HeartFlow (HTFL)
Market Price (6/24/2026): $34.56Market Cap: $3.0 BilSector: Health CareIndustry: Health Care Technology
Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.
Strong revenue growthRev Chg LTMRevenue Change % Last Twelve Months (LTM) is 41% Megatrend and thematic driversMegatrends include Biotechnology & Genomics, Precision Medicine, and Digital Health & Telemedicine. Themes include Advanced Diagnostics, Show more. | Weak multi-year price returns2Y Excs Rtn is -15%, 3Y Excs Rtn is -46% | Not profitable at operating income levelOp Inc LTMOperating Income, Last Twelve Months is -69 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -36% Not cash flow generativeCFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -37%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -40% Yield minus risk free rate is negativeERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -8.1% Key risksHTFL key risks include [1] a history of significant operating losses and [2] heavy revenue dependence on its single FFRCT Analysis product. |
| Strong revenue growthRev Chg LTMRevenue Change % Last Twelve Months (LTM) is 41% |
| Megatrend and thematic driversMegatrends include Biotechnology & Genomics, Precision Medicine, and Digital Health & Telemedicine. Themes include Advanced Diagnostics, Show more. |
| Weak multi-year price returns2Y Excs Rtn is -15%, 3Y Excs Rtn is -46% |
| Not profitable at operating income levelOp Inc LTMOperating Income, Last Twelve Months is -69 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -36% |
| Not cash flow generativeCFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -37%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -40% |
| Yield minus risk free rate is negativeERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -8.1% |
| Key risksHTFL key risks include [1] a history of significant operating losses and [2] heavy revenue dependence on its single FFRCT Analysis product. |
Qualitative Assessment
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HeartFlow (HTFL) stock has gained about 50% since 2/28/2026 because of the following key factors:
1. HeartFlow reported strong financial results for fiscal Q4 2025, which ended December 31, 2025, on March 18, 2026. The company's revenue increased by 40% year-over-year to $49.1 million, with full-year 2025 revenue also rising 40% to $176.0 million. Furthermore, HeartFlow provided an optimistic outlook for fiscal year 2026, projecting revenue between $218 million and $222 million, representing 24%–26% growth, and anticipated a non-GAAP gross margin of 80%–81%.
2. The company further boosted investor confidence with better-than-expected fiscal Q1 2026 earnings, which ended March 31, 2026, reported on May 14, 2026. HeartFlow announced an EPS of -$0.16, exceeding analyst consensus estimates by 27%, and recorded revenue of $52.6 million, surpassing estimates by 3.7% and demonstrating a 41.3% year-over-year increase. Following these results, management raised its fiscal year 2026 revenue guidance to $228 million–$232 million, indicating 29%–32% growth, and maintained its non-GAAP gross margin guidance of approximately 81%.
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HeartFlow (HTFL) stock has gained about 50% since 2/28/2026 because of the following key factors:
1. HeartFlow reported strong financial results for fiscal Q4 2025, which ended December 31, 2025, on March 18, 2026. The company's revenue increased by 40% year-over-year to $49.1 million, with full-year 2025 revenue also rising 40% to $176.0 million. Furthermore, HeartFlow provided an optimistic outlook for fiscal year 2026, projecting revenue between $218 million and $222 million, representing 24%–26% growth, and anticipated a non-GAAP gross margin of 80%–81%.
2. The company further boosted investor confidence with better-than-expected fiscal Q1 2026 earnings, which ended March 31, 2026, reported on May 14, 2026. HeartFlow announced an EPS of -$0.16, exceeding analyst consensus estimates by 27%, and recorded revenue of $52.6 million, surpassing estimates by 3.7% and demonstrating a 41.3% year-over-year increase. Following these results, management raised its fiscal year 2026 revenue guidance to $228 million–$232 million, indicating 29%–32% growth, and maintained its non-GAAP gross margin guidance of approximately 81%.
3. Expanded market access and favorable reimbursement mechanisms contributed to the positive stock trend. Aetna initiated coverage for HeartFlow Plaque Analysis across its Commercial, Medicare Advantage, and Aetna Better Health Medicaid plans, effective December 23, 2025, significantly broadening patient access. This move positioned Aetna as the fourth major national payer to align coverage with EviCore. Additionally, a new Category I CPT code (75577) became effective on January 1, 2026, establishing improved reimbursement for physicians utilizing HeartFlow's technology.
4. Sustained bullish sentiment from Wall Street analysts provided a supportive backdrop for the stock. Analysts maintained a consensus "Strong Buy" rating for HTFL, with an average price target ranging from $37.00 to $38.60. This positive outlook was attributed to the scalability of HeartFlow's AI-driven cardiac diagnostic platform and the momentum in plaque revenue, underpinning expectations for continued growth.
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Stock Movement Drivers
Fundamental Drivers
The 48.9% change in HTFL stock from 2/28/2026 to 6/23/2026 was primarily driven by a 0.0% change in the company's Total Revenues ($ Mil).| (LTM values as of) | 2282026 | 6232026 | Change |
|---|---|---|---|
| Stock Price ($) | 23.16 | 34.48 | 48.9% |
| Change Contribution By: | |||
| Total Revenues ($ Mil) | � | 191 | 0.0% |
| P/S Multiple | � | 15.4 | 0.0% |
| Shares Outstanding (Mil) | 64 | 86 | -25.4% |
| Cumulative Contribution | 0.0% |
Market Drivers
2/28/2026 to 6/23/2026| Return | Correlation | |
|---|---|---|
| HTFL | 48.9% | |
| Market (SPY) | 7.2% | 30.6% |
| Sector (XLV) | -4.6% | 18.2% |
Fundamental Drivers
The 6.9% change in HTFL stock from 11/30/2025 to 6/23/2026 was primarily driven by a 0.0% change in the company's Total Revenues ($ Mil).| (LTM values as of) | 11302025 | 6232026 | Change |
|---|---|---|---|
| Stock Price ($) | 32.25 | 34.48 | 6.9% |
| Change Contribution By: | |||
| Total Revenues ($ Mil) | � | 191 | 0.0% |
| P/S Multiple | � | 15.4 | 0.0% |
| Shares Outstanding (Mil) | 64 | 86 | -25.4% |
| Cumulative Contribution | 0.0% |
Market Drivers
11/30/2025 to 6/23/2026| Return | Correlation | |
|---|---|---|
| HTFL | 6.9% | |
| Market (SPY) | 8.0% | 38.6% |
| Sector (XLV) | -2.7% | 8.1% |
Fundamental Drivers
nullnull
Market Drivers
5/31/2025 to 6/23/2026| Return | Correlation | |
|---|---|---|
| HTFL | ||
| Market (SPY) | 25.9% | 32.2% |
| Sector (XLV) | 16.8% | 16.5% |
Fundamental Drivers
nullnull
Market Drivers
5/31/2023 to 6/23/2026| Return | Correlation | |
|---|---|---|
| HTFL | ||
| Market (SPY) | 82.4% | 32.2% |
| Sector (XLV) | 25.1% | 16.5% |
Price Returns Compared
| 2021 | 2022 | 2023 | 2024 | 2025 | 2026 | Total [1] | |
|---|---|---|---|---|---|---|---|
| Returns | |||||||
| HTFL Return | - | - | - | - | 1% | 16% | 18% |
| Peers Return | 20% | -19% | 13% | 12% | 13% | -25% | 4% |
| S&P 500 Return | 27% | -19% | 24% | 23% | 16% | 9% | 99% |
Monthly Win Rates [3] | |||||||
| HTFL Win Rate | - | - | - | - | 60% | 83% | |
| Peers Win Rate | 54% | 44% | 52% | 62% | 60% | 30% | |
| S&P 500 Win Rate | 75% | 42% | 67% | 75% | 67% | 50% | |
Max Drawdowns [4] | |||||||
| HTFL Max Drawdown | - | - | - | - | - | -45% | |
| Peers Max Drawdown | -18% | -34% | -22% | -19% | -18% | -32% | |
| S&P 500 Max Drawdown | -5% | -25% | -10% | -8% | -19% | -9% | |
[1] Cumulative total returns since the beginning of 2021
[2] Peers: BSX, MDT, EW, ABT, GEHC.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 6/23/2026 (YTD)
How Low Can It Go
HTFL has limited trading history. Below is the Health Care sector ETF (XLV) in its place.
| Event | XLV | S&P 500 |
|---|---|---|
| 2025 US Tariff Shock | ||
| % Loss | -11.7% | -18.8% |
| % Gain to Breakeven | 13.3% | 23.1% |
| Time to Breakeven | 142 days | 79 days |
| 2022 Inflation Shock & Fed Tightening | ||
| % Loss | -13.8% | -24.5% |
| % Gain to Breakeven | 15.9% | 32.4% |
| Time to Breakeven | 166 days | 427 days |
| 2020 COVID-19 Crash | ||
| % Loss | -27.9% | -33.7% |
| % Gain to Breakeven | 38.8% | 50.9% |
| Time to Breakeven | 77 days | 140 days |
| Q4 2018 Fed Policy Error / Growth Scare | ||
| % Loss | -15.0% | -19.2% |
| % Gain to Breakeven | 17.6% | 23.8% |
| Time to Breakeven | 191 days | 105 days |
| 2015-2016 China Devaluation / Global Growth Scare | ||
| % Loss | -15.9% | -12.2% |
| % Gain to Breakeven | 18.9% | 13.9% |
| Time to Breakeven | 165 days | 62 days |
| 2011 US Debt Ceiling Crisis & European Contagion | ||
| % Loss | -15.8% | -17.9% |
| % Gain to Breakeven | 18.8% | 21.8% |
| Time to Breakeven | 153 days | 123 days |
In The Past
State Street Health Care Select Sector SPDR ETF's stock fell -11.7% during the 2025 US Tariff Shock. Such a loss loss requires a 13.3% gain to breakeven.
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HTFL has limited trading history. Below is the Health Care sector ETF (XLV) in its place.
| Event | XLV | S&P 500 |
|---|---|---|
| 2020 COVID-19 Crash | ||
| % Loss | -27.9% | -33.7% |
| % Gain to Breakeven | 38.8% | 50.9% |
| Time to Breakeven | 77 days | 140 days |
| 2008-2009 Global Financial Crisis | ||
| % Loss | -37.9% | -53.4% |
| % Gain to Breakeven | 61.1% | 114.4% |
| Time to Breakeven | 767 days | 1085 days |
In The Past
State Street Health Care Select Sector SPDR ETF's stock fell -11.7% during the 2025 US Tariff Shock. Such a loss loss requires a 13.3% gain to breakeven.
Preserve Wealth
Limiting losses and compounding gains is essential to preserving wealth.
Asset Allocation
Actively managed asset allocation strategies protect wealth. Learn more.
About HeartFlow (HTFL)
HeartFlow (HTFL) is a medical technology company that leverages advanced software and AI to provide a more accurate and clinically effective non-invasive solution for diagnosing and managing Coronary Artery Disease (CAD), a leading cause of death worldwide. The company's platform takes data from a single Coronary Computed Tomography Angiography (CCTA) scan to generate a personalized 3D model of a patient’s heart. This proprietary technology uses AI and computational fluid dynamics to deliver actionable insights on blood flow, stenosis, plaque volume, and plaque composition, directly addressing the limitations of traditional non-invasive imaging tests and standard CCTA scans.
HeartFlow's main commercial products are the Heartflow FFRCT Analysis and Heartflow Plaque Analysis. The FFRCT Analysis, which represents 99% of current revenue, calculates fractional flow reserve (FFR) to pinpoint clinically significant CAD, guiding decisions on invasive revascularization. The Plaque Analysis provides a comprehensive assessment of coronary plaque to optimize medical treatment strategies. Both products generate revenue on a "pay-per-click" basis each time a physician reviews an analysis. The company also offers workflow efficiency tools like RoadMap Analysis and plans to launch Heartflow PCI Planner in 2026 to enhance revascularization strategies.
HeartFlow primarily serves cardiologists and healthcare providers involved in the diagnosis and management of symptomatic CAD patients, covering both stable and acute chest pain scenarios. The company estimates its current U.S. market opportunity for FFRCT and Plaque Analysis at approximately $5 billion. Its platform is widely validated by over 100 clinical studies and supported by strong clinical guidelines from organizations like the AHA and ACC. Furthermore, the Heartflow FFRCT Analysis has a dedicated Category I CPT code with established reimbursement coverage for approximately 99% of covered lives in the U.S., with Plaque Analysis slated to receive its own Category I CPT code in 2026.
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Here are 1-3 brief analogies for HeartFlow (HTFL):
- Think of HeartFlow as the 'Google Maps' for your heart's arteries, providing precise, AI-powered navigation through blood flow and blockages.
- It's like the 'FICO score' for heart health, using AI to turn complex scans into a clear, quantifiable measure of risk and treatment guidance.
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- Heartflow FFRCT Analysis: This service utilizes AI and computational fluid dynamics to calculate blood flow and identify clinically significant coronary artery disease (CAD) from CCTA scans.
- Heartflow Plaque Analysis: This service provides an AI-powered comprehensive assessment of coronary plaque, enabling optimized medical treatment strategies based on CCTA scans.
- Heartflow RoadMap Analysis: An integrated feature that offers intuitive anatomic visualization of coronary arteries to enhance the efficiency of CCTA review processes for physicians.
- Heartflow PCI Planner: An upcoming integrated feature (expected 2026) that will provide advanced visualization and clinical insights to optimize revascularization strategies and guide device selection.
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HeartFlow (HTFL) primarily sells its software platform and analysis services to other companies, specifically healthcare providers and institutions.
The provided text does not list specific names of customer companies or their public symbols.
HeartFlow's customers are typically:
- Hospitals: The company's platform improves the efficiency and economics of catheterization labs and overall hospital workflows related to diagnosing and managing coronary artery disease (CAD).
- Cardiology Centers and Clinics: These are the facilities where physicians, particularly cardiologists, utilize the HeartFlow Platform to interpret CCTA scans, diagnose CAD, and plan patient treatment pathways.
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John Farquhar, President and Chief Executive Officer
John Farquhar was appointed President and Chief Executive Officer of HeartFlow on March 1, 2022, having joined the company in August 2021 as Chief Operating Officer. He brings over 20 years of leadership experience in the medical technology industry, previously holding various senior roles at Medtronic. His positions at Medtronic included Vice President and General Manager of the Aortic business, and Vice President for the Americas region for the Insulin Pump and Continuous Glucose Monitoring business unit, as well as Vice President for Asia Pacific within the Cardiovascular and Diabetes Groups. Farquhar holds a Bachelor of Arts degree from Duke University and an MBA from Northwestern University's Kellogg School of Management.
Monica Tellado, Chief Financial Officer
Monica Tellado assumed the role of Chief Financial Officer at HeartFlow on April 4, 2022. Before joining HeartFlow, she served as Senior Vice President of Finance at Gilead, where she was responsible for global finance teams and investor relations. During her 18-year tenure at Gilead, Tellado held increasingly responsible roles across finance and commercial organizations, including leading U.S. and Latin American commercial teams, and supporting new market entries and product launches in various business units. She also managed the U.S. Liver Disease business unit, overseeing a P&L of nearly $2 billion. Her earlier career included finance positions at Intel Corporation and Ford Motor Company. Ms. Tellado earned a Bachelor of Arts degree in Business Administration from Universidad Pontificia Comillas and an MBA from Carnegie Mellon University.
Charles Taylor, Founder, Chief Technology Officer
Charles Taylor is a co-founder of HeartFlow, Inc., established in 2010, and its predecessor, Cardiovascular Simulation, Inc., in 2007, serving as the Chief Technology Officer. Prior to his work with HeartFlow, he was an Associate Professor of Bioengineering and Surgery at Stanford University, starting in 1997. At Stanford, he concentrated on developing computer modeling and imaging techniques for cardiovascular disease research, device design, and surgical planning. His early research includes the first three-dimensional simulations of blood flow in the human abdominal aorta and the first simulations of blood flow in vascular models derived from medical imaging data. He is credited with initiating the field of predictive, simulation-based medicine by applying computational fluid dynamics to forecast outcomes of cardiovascular interventions in individual patients.
Campbell Rogers, Chief Medical Officer
Campbell Rogers serves as the Chief Medical Officer for HeartFlow. Before joining HeartFlow, he was the Chief Scientific Officer and Global Head of Research and Development at Cordis Corporation, a Johnson & Johnson company, where he was responsible for leading investments and research in cardiovascular devices. Prior to his time at Cordis, Dr. Rogers was an Associate Professor of Medicine at Harvard Medical School and the Director of the Cardiac Catheterization Laboratory at Brigham and Women's Hospital in Boston.
Kathleen Carey, Senior Vice President, Operations
Kathleen Carey holds the position of Senior Vice President, Operations at HeartFlow.
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The key risks to HeartFlow's business are:
-
Heavy Reliance on Heartflow FFRCT Analysis for Revenue: As of March 31, 2025, Heartflow FFRCT Analysis represented 99% of HeartFlow's total revenue. This significant concentration on a single product makes the company highly vulnerable to any factors that could negatively impact its adoption, reimbursement, or market position, such as changes in clinical guidelines, payor policies, or competitive landscape.
-
Successful Commercialization and Adoption of New Products: While HeartFlow has introduced Heartflow Plaque Analysis and plans to launch Heartflow PCI Planner in 2026, their current revenue contribution is minimal. The company's future growth and diversification are contingent upon the successful market penetration and widespread physician adoption of these new products. Failure to achieve this could prolong the company's reliance on Heartflow FFRCT Analysis and limit its ability to capture new market opportunities.
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HeartFlow (HTFL) has identified the following addressable market opportunities for its main products and services:
- The combined market opportunity in the United States for Heartflow FFRCT Analysis and Heartflow Plaque Analysis is approximately $5 billion.
- For Heartflow FFRCT Analysis, the estimated market opportunity in the United States is approximately $3.3 billion, based on an estimated 3.1 million eligible patients and a U.S. average sales price of $1,067.
- For Heartflow Plaque Analysis, the estimated incremental market opportunity in the United States is approximately $1.7 billion, based on an estimated 5.5 million eligible patients and an estimated U.S. sales price of $300.
- Beyond symptomatic CAD, HeartFlow sees a significant global market opportunity for its technologies in at-risk individuals who show no symptoms, a segment comprised of approximately 200 million people globally.
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Expected Drivers of Future Revenue Growth for HeartFlow (HTFL)
- Commercialization and Reimbursement of Heartflow Plaque Analysis: HeartFlow anticipates significant revenue growth from its Heartflow Plaque Analysis product. This product, which began limited market education in the second half of 2023, is poised for accelerated adoption with the establishment of a dedicated Category I CPT code effective January 1, 2026. This code will ensure coverage by all seven Medicare administrative contractors (MACs), unlocking an estimated incremental market opportunity of approximately $1.7 billion in the United States.
- Continued Adoption and Increased Utilization of Heartflow FFRCT Analysis: As the commercial foundation representing 99% of HeartFlow's total revenue as of March 31, 2025, the Heartflow FFRCT Analysis continues to be a core growth driver. Supported by established Category I CPT codes and coverage for approximately 99% of covered lives in the United States, there remains a substantial market opportunity of approximately 3.1 million eligible patients, translating to an estimated $3.3 billion in the U.S.
- Launch of Heartflow PCI Planner in 2026: HeartFlow expects to launch its fourth product, Heartflow PCI Planner, in 2026. While provided as an integrated feature rather than a stand-alone product, this advanced visualization and clinical insights tool is designed to optimize revascularization strategies, guide device selection, and enhance procedural efficiency. By improving workflow and patient care, it is expected to strengthen the overall value proposition of the Heartflow Platform, potentially driving broader adoption and increased utilization of the revenue-generating FFRCT and Plaque Analyses.
- Advancement of the "CCTA + Heartflow" Pathway as the Standard of Care: HeartFlow aims to establish the "CCTA + Heartflow" pathway as the definitive standard for non-invasive diagnosis and management of coronary artery disease. This is driven by the platform's demonstrated accuracy, clinical utility, and economic benefits, supported by strong clinical evidence from over 100 studies and consistent guideline support from organizations like the AHA and ACC. Increased physician and institutional adoption of this pathway, leveraging the platform's workflow efficiencies (e.g., Heartflow RoadMap Analysis), is expected to drive overall revenue growth.
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Capital Expenditures
- HeartFlow's technology is designed not to require the purchase of any capital equipment, suggesting a capital-efficient operational model.
Latest Trefis Analyses
| Title | Date | |
|---|---|---|
| DASHBOARDS | ||
| HeartFlow Stock 7-Day Winning Spree: Stock Climbs 37% | 03/25/2026 | |
| HeartFlow Stock On Fire: Up 31% With 6-Day Winning Streak | 03/24/2026 | |
| HeartFlow Stock (-7.6%): Insider Sale and Tech Critique Amid Sector Weakness | 03/07/2026 | |
| HeartFlow Earnings Notes | 12/31/2026 | |
| HeartFlow Stock (+9%): Insider Buy Signals Bottoming Process | 12/19/2025 |
| Title | |
|---|---|
| ARTICLES |
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Peer Comparisons
| Peers to compare with: |
Financials
| Median | |
|---|---|
| Name | |
| Mkt Price | 72.17 |
| Mkt Cap | 59.0 |
| Rev LTM | 20,797 |
| Op Inc LTM | 3,378 |
| FCF LTM | 2,408 |
| FCF 3Y Avg | 2,525 |
| CFO LTM | 3,184 |
| CFO 3Y Avg | 3,543 |
Growth & Margins
| Median | |
|---|---|
| Name | |
| Rev Chg LTM | 11.3% |
| Rev Chg 3Y Avg | 5.2% |
| Rev Chg Q | 10.7% |
| QoQ Delta Rev Chg LTM | 2.6% |
| Op Inc Chg LTM | 6.2% |
| Op Inc Chg 3Y Avg | 4.7% |
| Op Mgn LTM | 17.9% |
| Op Mgn 3Y Avg | 18.4% |
| QoQ Delta Op Mgn LTM | 0.1% |
| CFO/Rev LTM | 20.6% |
| CFO/Rev 3Y Avg | 19.9% |
| FCF/Rev LTM | 15.5% |
| FCF/Rev 3Y Avg | 14.0% |
Segment Financials
Revenue by Segment| $ Mil | 2025 | 2024 | 2023 |
|---|---|---|---|
| Non-invasive coronary artery disease (CAD) detection solutions | 176 | 126 | 87 |
| Total | 176 | 126 | 87 |
| $ Mil | 2025 | 2024 | 2023 |
|---|---|---|---|
| Non-invasive coronary artery disease (CAD) detection solutions | -64 | -61 | -73 |
| Total | -64 | -61 | -73 |
| $ Mil | 2025 | 2024 | 2023 |
|---|---|---|---|
| Non-invasive coronary artery disease (CAD) detection solutions | -117 | -96 | -96 |
| Total | -117 | -96 | -96 |
Price Behavior
| Market Price | $34.48 | |
| Market Cap ($ Bil) | 3.0 | |
| First Trading Date | 08/08/2025 | |
| Distance from 52W High | -13.6% | |
| 50 Days | 200 Days | |
| DMA Price | $31.62 | $31.62 |
| DMA Trend | indeterminate | up |
| Distance from DMA | 9.1% | 9.1% |
| 3M | 1YR | |
| Volatility | 61.1% | 74.9% |
| Downside Capture | 238.66 | 239.06 |
| Upside Capture | 216.88 | 217.11 |
| Correlation (SPY) | 38.3% |
| 1M | 2M | 3M | 6M | 1Y | 3Y | |
|---|---|---|---|---|---|---|
| Beta | 3.52 | 2.35 | 1.61 | 2.51 | 0.13 | 0.20 |
| Up Beta | 0.83 | 0.07 | -0.20 | 1.28 | -0.33 | 0.49 |
| Down Beta | 6.59 | 4.68 | 1.44 | 3.53 | -0.60 | 0.72 |
| Up Capture | 271% | 310% | 326% | 312% | 267% | 24% |
| Bmk +ve Days | 13 | 28 | 36 | 67 | 141 | 432 |
| Stock +ve Days | 12 | 27 | 39 | 66 | 106 | 106 |
| Down Capture | 541% | 533% | 215% | 233% | 172% | 87% |
| Bmk -ve Days | 7 | 13 | 27 | 57 | 109 | 318 |
| Stock -ve Days | 8 | 13 | 23 | 57 | 94 | 94 |
[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
| Annualized Return | Annualized Volatility | Sharpe Ratio | Correlation with HTFL | |
|---|---|---|---|---|
| HTFL | 20.0% | 74.9% | 0.60 | - |
| Sector ETF (XLV) | 16.9% | 15.1% | 0.83 | 16.5% |
| Equity (SPY) | 24.6% | 12.5% | 1.48 | 32.2% |
| Gold (GLD) | 21.8% | 27.6% | 0.70 | 4.7% |
| Commodities (DBC) | 16.7% | 18.8% | 0.69 | -3.5% |
| Real Estate (VNQ) | 12.3% | 13.8% | 0.60 | 13.4% |
| Bitcoin (BTCUSD) | -38.0% | 42.5% | -1.01 | 27.0% |
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Based On 5-Year Data
| Annualized Return | Annualized Volatility | Sharpe Ratio | Correlation with HTFL | |
|---|---|---|---|---|
| HTFL | 3.7% | 74.9% | 0.60 | - |
| Sector ETF (XLV) | 5.8% | 14.8% | 0.21 | 16.5% |
| Equity (SPY) | 13.1% | 17.1% | 0.59 | 32.2% |
| Gold (GLD) | 16.8% | 18.3% | 0.74 | 4.7% |
| Commodities (DBC) | 7.3% | 19.4% | 0.28 | -3.5% |
| Real Estate (VNQ) | 2.4% | 18.9% | 0.03 | 13.4% |
| Bitcoin (BTCUSD) | 9.7% | 54.1% | 0.38 | 27.0% |
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Based On 10-Year Data
| Annualized Return | Annualized Volatility | Sharpe Ratio | Correlation with HTFL | |
|---|---|---|---|---|
| HTFL | 1.8% | 74.9% | 0.60 | - |
| Sector ETF (XLV) | 9.8% | 16.6% | 0.48 | 16.5% |
| Equity (SPY) | 15.3% | 18.0% | 0.73 | 32.2% |
| Gold (GLD) | 11.9% | 16.1% | 0.61 | 4.7% |
| Commodities (DBC) | 5.9% | 18.0% | 0.25 | -3.5% |
| Real Estate (VNQ) | 5.5% | 20.7% | 0.23 | 13.4% |
| Bitcoin (BTCUSD) | 57.0% | 66.5% | 0.97 | 27.0% |
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Earnings Returns History
Updated 6/18/2026| Forward Returns | |||
|---|---|---|---|
| Earnings Date | 1D Returns | 5D Returns | 21D Returns |
| 5/14/2026 | -12.2% | -9.4% | 1.8% |
| 3/18/2026 | 1.6% | 9.0% | 23.0% |
| 11/12/2025 | -13.4% | -23.8% | -28.3% |
| SUMMARY STATS | |||
| # Positive | 1 | 1 | 2 |
| # Negative | 2 | 2 | 1 |
| Median Positive | 1.6% | 9.0% | 12.4% |
| Median Negative | -12.8% | -16.6% | -28.3% |
| Max Positive | 1.6% | 9.0% | 23.0% |
| Max Negative | -13.4% | -23.8% | -28.3% |
| Forward Returns | |||
|---|---|---|---|
| Earnings Date | 1D Returns | 5D Returns | 21D Returns |
| 5/14/2026 | -12.2% | -9.4% | 1.8% |
| 3/18/2026 | 1.6% | 9.0% | 23.0% |
| 11/12/2025 | -13.4% | -23.8% | -28.3% |
| SUMMARY STATS | |||
| # Positive | 1 | 1 | 2 |
| # Negative | 2 | 2 | 1 |
| Median Positive | 1.6% | 9.0% | 12.4% |
| Median Negative | -12.8% | -16.6% | -28.3% |
| Max Positive | 1.6% | 9.0% | 23.0% |
| Max Negative | -13.4% | -23.8% | -28.3% |
Recent Forward Guidance
Updated 6/1/2026Latest: Q1 2026 Earnings Reported 5/14/2026
| Forward Guidance | Guidance Change | ||||||
|---|---|---|---|---|---|---|---|
| Metric | Low | Mid | High | % Chg | % Delta | Change | Prior |
| 2026 Revenue | 228.00 Mil | 230.00 Mil | 232.00 Mil | 4.5% | Raised | Guidance: 220.00 Mil for 2026 | |
| 2026 Revenue Growth | 29.0% | 30.5% | 32.0% | 22.0% | 5.5% | Raised | Guidance: 25.0% for 2026 |
| 2026 Non-GAAP Gross Margin | 81.0% | 0.6% | 0.5% | Raised | Guidance: 80.5% for 2026 | ||
Prior: Q4 2025 Earnings Reported 3/18/2026
| Forward Guidance | Guidance Change | ||||||
|---|---|---|---|---|---|---|---|
| Metric | Low | Mid | High | % Chg | % Delta | Change | Prior |
| 2026 Revenue | 218.00 Mil | 220.00 Mil | 222.00 Mil | 27.0% | Raised | Guidance: 173.25 Mil for 2025 | |
| 2026 Revenue Growth | 24.0% | 25.0% | 26.0% | -33.8% | -12.8% | Lowered | Guidance: 37.75% for 2025 |
| 2026 Non-GAAP Gross Margin | 80.0% | 80.5% | 81.0% | ||||
Insider Activity
Updated 6/18/2026| # | Owner | Title | Holding | Action | Filing Date | Price | Shares | Transacted Value | Value of Held Shares | Form |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Farquhar, John CM | Chief Executive Officer | Direct | Sell | 6122026 | 28.50 | 22,562 | 643,017 | 14,159,798 | Form |
| 2 | Rogers, Campbell | Chief Medical Officer | Direct | Sell | 5202026 | 28.34 | 9,219 | 261,266 | 2,231,237 | Form |
| 3 | Farquhar, John CM | Chief Executive Officer | Direct | Sell | 5132026 | 29.12 | 22,562 | 657,005 | 15,124,841 | Form |
| 4 | Bain, Capital Life Sciences Investors, Llc | See footnotes | Sell | 4302026 | 29.23 | 948,757 | 27,733,644 | 246,952,810 | Form | |
| 5 | Bain, Capital Life Sciences Investors, Llc | See footnotes | Sell | 4302026 | 29.37 | 797,133 | 23,411,796 | 275,987,394 | Form |
| # | Owner | Title | Holding | Action | Filing Date | Price | Shares | Transacted Value | Value of Held Shares | Form |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Farquhar, John CM | Chief Executive Officer | Direct | Sell | 6122026 | 28.50 | 22,562 | 643,017 | 14,159,798 | Form |
| 2 | Rogers, Campbell | Chief Medical Officer | Direct | Sell | 5202026 | 28.34 | 9,219 | 261,266 | 2,231,237 | Form |
| 3 | Farquhar, John CM | Chief Executive Officer | Direct | Sell | 5132026 | 29.12 | 22,562 | 657,005 | 15,124,841 | Form |
| 4 | Bain, Capital Life Sciences Investors, Llc | See footnotes | Sell | 4302026 | 29.23 | 948,757 | 27,733,644 | 246,952,810 | Form | |
| 5 | Bain, Capital Life Sciences Investors, Llc | See footnotes | Sell | 4302026 | 29.37 | 797,133 | 23,411,796 | 275,987,394 | Form | |
| 6 | Bain, Capital Life Sciences Investors, Llc | See footnotes | Sell | 4302026 | 30.51 | 254,110 | 7,752,896 | 311,020,404 | Form | |
| 7 | Farquhar, John CM | Chief Executive Officer | Direct | Sell | 4142026 | 26.72 | 22,562 | 602,857 | 14,673,635 | Form |
| 8 | Rogers, Campbell | Chief Medical Officer | Direct | Sell | 4032026 | 24.64 | 64,533 | 1,590,093 | 1,995,889 | Form |
| 9 | Rogers, Campbell | Chief Medical Officer | Direct | Sell | 3232026 | 25.69 | 64,533 | 1,658,033 | 2,017,347 | Form |
| 10 | Farquhar, John CM | Chief Executive Officer | Direct | Sell | 3202026 | 25.00 | 9,725 | 243,125 | 14,293,125 | Form |
| 11 | Farquhar, John CM | Chief Executive Officer | Direct | Sell | 3122026 | 22.66 | 12,837 | 290,886 | 13,175,657 | Form |
| 12 | Cullivan, Julie A | Direct | Sell | 3062026 | 25.00 | 9,122 | 228,050 | 682,275 | Form | |
| 13 | Rogers, Campbell | Chief Medical Officer | Direct | Sell | 2172026 | 24.49 | 65,153 | 1,595,486 | 1,861,943 | Form |
| 14 | Farquhar, John CM | Chief Executive Officer | Direct | Sell | 2102026 | 27.46 | 22,562 | 619,553 | 16,246,874 | Form |
| 15 | Cullivan, Julie A | Direct | Sell | 2062026 | 27.32 | 8,000 | 218,560 | 994,803 | Form | |
| 16 | Bain, Capital Life Sciences Investors, Llc | See footnotes | Sell | 2062026 | 28.05 | 2,000,000 | 56,100,000 | 293,070,832 | Form | |
| 17 | Lightcap, Jeffrey C | Direct | Buy | 12172025 | 26.34 | 40,000 | 1,053,680 | 1,053,680 | Form |
Industry Resources
| Health Care Resources |
| U.S. National Library of Medicine |
| ClinicalTrials.gov |
| Modern Healthcare |
| Healthcare Dive |
| Fierce Healthcare |
| Health Affairs |
| Health Data Management |
| FDA Tracker |
| Health Care Technology Resources |
| Healthcare IT News |
| MobiHealthNews |
| HealthTech Magazine |
External Quote Links
| Y Finance | Barrons |
| TradingView | Morningstar |
| SeekingAlpha | ValueLine |
| Motley Fool | Robinhood |
| CNBC | Etrade |
| MarketWatch | Unusual Whales |
| YCharts | Perplexity Finance |
| FinViz |
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