Here are 1-3 brief analogies for Anika Therapeutics (ANIK):

• A focused Johnson & Johnson for joint health, offering both non-surgical pain relief and surgical repair solutions.
• A Stryker or Zimmer Biomet for joint preservation and regenerative medicine.

• Viscosupplements: A family of hyaluronic acid (HA) injections (e.g., MONOVISC®, ORTHOVISC®, CINGAL®) used to treat pain and improve joint function in osteoarthritis of the knee.
• Bone Repair and Fixation Systems: A range of devices (e.g., Mini-Mag™, Hemi-Mag™, X-Twist™) designed for fracture fixation, osteotomy, and other orthopedic bone repair procedures.
• Soft Tissue Repair Systems: Solutions (e.g., Tendonex™) used to augment or repair damaged tendons and other soft tissues in orthopedic applications.
• Total Ankle Replacement (TAR) System: The TACTAR™ Total Ankle Arthroplasty System is a device designed to replace damaged ankle joints, restoring mobility and reducing pain.

Anika Therapeutics (ANIK) primarily sells its products to other companies and healthcare organizations (B2B model).

According to the company's SEC filings, no single customer accounted for more than 10% of its consolidated net sales in recent fiscal years, indicating a diversified customer base rather than reliance on a few major accounts. Therefore, specific "major customer" company names with associated stock symbols cannot be identified.

The company's customer base is comprised of various entities within the healthcare industry, including:

• Hospitals: These institutions are direct purchasers and end-users of Anika's therapeutic products for patient care.
• Orthopedic Clinics and Healthcare Professionals: Specialists such as orthopedic surgeons within clinics or private practices purchase and utilize Anika's products.
• Group Purchasing Organizations (GPOs): These organizations represent groups of hospitals and other healthcare providers, negotiating purchasing contracts for medical supplies, including Anika's products.
• Independent Distributors: Anika partners with domestic and international distributors who purchase products from Anika and then resell them to the various healthcare providers mentioned above, particularly in markets where Anika does not have a direct sales force.

Cheryl R. Blanchard, Ph.D. President and Chief Executive Officer

Dr. Blanchard was appointed President and Chief Executive Officer of Anika Therapeutics in April 2020, after serving as interim CEO since February 2020. She joined Anika's Board of Directors in August 2018. Prior to Anika, she served as President and Chief Executive Officer of Microchips Biotech, Inc., a venture-backed biotechnology company, from 2014 until its sale to Daré Bioscience, Inc. in November 2019. From 2000 to 2012, she held various officer positions at Zimmer, Inc. (now Zimmer Biomet), including Senior Vice President, Chief Scientific Officer, and General Manager of Zimmer Biologics, where she founded and led the company's Joint Preservation/Regenerative Medicine business. Since 2012, Dr. Blanchard has also been a Principal at Blanchard Consulting, LLC, providing scientific, regulatory, and business strategy consulting services to medical device companies and private equity clients.

Steve Griffin Executive Vice President, Chief Financial Officer and Chief Operating Officer

Mr. Griffin was appointed Executive Vice President, Chief Financial Officer and Chief Operating Officer in April 2025, having joined Anika in June 2024. Most recently, he served as Senior Vice President and Chief Financial Officer at VSE Corporation, where he helped execute a strategic transformation involving organic growth, six acquisitions, and two divestitures. Before his tenure at VSE Corporation, Mr. Griffin spent over a decade at General Electric in senior finance leadership roles, including Corporate Audit, Financial Planning and Analysis, and Divisional CFO roles across GE Healthcare, GE Aerospace, and GE Power. He is also a graduate of GE's financial management program.

David Colleran Executive Vice President, General Counsel and Corporate Secretary

Mr. Colleran joined Anika in March 2020 as Executive Vice President, General Counsel and Corporate Secretary. Prior to Anika, he served as Senior Vice President, General Counsel, Corporate Secretary, and Chief Compliance Officer at Insulet Corporation from 2015 to 2019, where he provided legal and strategic support for financial transactions and a corporate headquarters acquisition. Earlier in his career, Mr. Colleran was Vice President and General Counsel for the Medical Supplies Sector at Covidien (now Medtronic) and Corporate Counsel at Ocean Spray Cranberries, Inc. He began his legal career as a corporate associate at Choate, Hall and Stewart.

James Chase Senior Vice President, International Sales and Marketing

Mr. Chase was appointed Senior Vice President of International Sales and Marketing in May 2020. He initially joined Anika Therapeutics in August 2018 as Vice President of International Sales. Before joining Anika, Mr. Chase served as the Business Unit Director of the Sports Medicine Division of Smith & Nephew for the United Kingdom and Ireland. He also held several other senior leadership positions at Smith & Nephew, including General Manager UK/Ireland, Vice President Northern Europe, and Managing Director UK/Ireland, where he successfully led large commercial teams.

Steven Ek Vice President, Research and Development

Mr. Ek serves as Vice President, Research and Development at Anika Therapeutics. He is one of the original founders of Arthrosurface, which was acquired by Anika Therapeutics, and previously served as its President and Chief Executive Officer, a role he assumed in November 2012. Mr. Ek has over 30 years of experience in the medical and hospital equipment industry, with a focus on orthopedics and sports medicine. His prior roles include Vice President of Engineering at STD Med, Inc. and Director of Research & Development at Smith & Nephew Endoscopy for nine years.

Anika Therapeutics (symbol: ANIK) focuses on hyaluronic acid (HA) technology for osteoarthritis (OA) pain management and regenerative solutions. The addressable markets for their main products and services are as follows:

• Overall HA Technology and Regenerative Solutions: The total addressable global market for Anika's core hyaluronic acid (HA) technology and differentiated Regenerative Solutions portfolio is estimated to be $4 billion.
• Cingal (OA Pain Management): Anika anticipates that Cingal, a next-generation, non-opioid, single-injection OA pain product, will address an incremental U.S. market of at least $1 billion.
• Integrity Implant System (Regenerative Solutions - Tendon Augmentation): The Integrity Implant System competes in the U.S. tendon augmentation market, which is estimated to be more than $220 million annually.
• Hyalofast (Regenerative Solutions - Cartilage Repair): Anika is preparing for the U.S. launch of Hyalofast, a single-stage, off-the-shelf cartilage repair therapy, which is expected to represent an incremental U.S. addressable market of at least $1 billion. The global cartilage repair market is projected to grow from $1.6 billion in 2025 to $3 billion by 2035.

For broader context, Anika Therapeutics operates within the following larger markets:

• Global Osteoarthritis Therapeutics Market: This market was approximately US$ 9.95 billion in 2024 and is forecast to rise to US$ 10.89 billion by 2025, with projections to reach US$ 24.52 billion by 2034.
• U.S. Osteoarthritis Therapeutics Market: This market is valued at approximately US$ 3.27 billion in 2024, expected to grow to US$ 3.5 billion in 2025, and projected to reach around US$ 6.46 billion by 2034.
• Global Joint Pain Injections Market: This market was valued at approximately USD 6.3 billion in 2021.

Expected Drivers of Future Revenue Growth for Anika Therapeutics (ANIK)

• Continued Growth of the Integrity Implant System: The Integrity Implant System has demonstrated robust performance, with U.S. procedures growing for six consecutive quarters and a 25% year-over-year increase in Regenerative Solutions. The company aims to more than double Integrity procedures and revenue in 2025 compared to the previous year, driven by expanding adoption and repeat use among surgeons.
• Expansion and U.S. Launch of Hyalofast: Anika is experiencing strong international growth with Hyalofast. A significant milestone was achieved with the submission of the third and final Premarket Approval (PMA) module for Hyalofast to the U.S. FDA, positioning it for future market opportunities in the U.S.
• International Market Expansion and Growth in OA Pain Management: Anika is focused on driving international sales by expanding market share in established regions and accelerating growth in new markets with its current product portfolio, particularly within OA Pain Management.
• Launch of New Products and Product Line Extensions: The company has initiated the limited release of larger Integrity shapes for expanded tendon applications, with plans for additional SKUs in upcoming quarters. New product launches and expansions are expected to contribute to continued strong growth in the commercial channel.

Share Repurchases

• In May 2019, Anika Therapeutics authorized a $50 million share repurchase program, which included a $30 million accelerated share repurchase (ASR) to be completed by the second quarter of 2020, and up to $20 million for open market repurchases.
• A new $40 million share repurchase program was authorized in May 2024, replacing a prior April 2023 authorization. This program includes a $15 million 10b5-1 trading plan to be executed by June 30, 2025, with the remainder for open market purchases.
• A second $15 million share repurchase program commenced in Q3 2025, with an expected completion by June 2026.

Share Issuance

• An Inducement Plan has reserved 350,000 shares of common stock for equity-based awards, specifically for individuals not previously employees or directors of the company.

Outbound Investments

• In January 2020, Anika acquired Parcus Medical for an upfront cash payment of approximately $35 million, with an additional $60 million contingent on achieving specific commercial milestones.
• Also in January 2020, Anika acquired Arthrosurface for an upfront cash payment of $60 million, plus an additional $40 million contingent upon successful regulatory and commercial milestones.
• Anika completed the sale of its Arthrosurface asset group in October 2024 and its Parcus Medical business to Medacta Group SA in March 2025.

Capital Expenditures

• Cash used in investing activities, primarily for capital expenditures, amounted to $8.3 million in 2024, $5.4 million in 2023, and $7.5 million in 2022.
• The increase in 2024 capital expenditures was mainly allocated to expanding manufacturing capacity at the Bedford facility and included a $0.6 million purchase of developed technology.
• In Q3 2025, capital expenditures were $1.9 million, focusing on expanding the Massachusetts manufacturing facility's capacity to support anticipated volume growth for products such as Monovisc, Cingal, Integrity, and Hyalofast.