Tearsheet

NewAmsterdam Pharma (NAMS)


Market Price (10/31/2025): $38.69 | Market Cap: $4.6 Bil
Sector: Health Care | Industry: Biotechnology

NewAmsterdam Pharma (NAMS)


Market Price (10/31/2025): $38.69
Market Cap: $4.6 Bil
Sector: Health Care
Industry: Biotechnology

Investment Highlights Why It Matters Which of these 2 stories sounds closer for this stock?

1. Generates cash flow

The stock generated 4% or more of the share price (called cash flow yield), and shows moderate 10-15% or more growth.

2. Riding a trend

Think Tesla during the pandemic of 2020 when EVs were riding a cultural high, or Nvidia in the current AI boom, or even Figma. These companies don’t have enough yield, or, enough growth, or both - however - they are riding a trend. They have momentum. These can be more volatile - they don’t have the floor of strong cash flow


0 Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -16%
Trading close to highs
Dist 52W High is -4.3%
Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -175 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -273%
1 Strong revenue growth
Rev Chg LTMRevenue Change % Last Twelve Months (LTM) is 762%
  Expensive valuation multiples
P/SPrice/Sales ratio is 72x
2 Valuation becoming less expensive
P/S 6M Chg %Price/Sales change over 6 months. Declining P/S indicates valuation has become less expensive. is -40%
  Stock price has recently run up significantly
12M Rtn12 month market price return is 115%
3   Not cash flow generative
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -194%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -194%
4   Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -8.1%
0 Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -16%
1 Strong revenue growth
Rev Chg LTMRevenue Change % Last Twelve Months (LTM) is 762%
2 Valuation becoming less expensive
P/S 6M Chg %Price/Sales change over 6 months. Declining P/S indicates valuation has become less expensive. is -40%
3 Trading close to highs
Dist 52W High is -4.3%
4 Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -175 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -273%
5 Expensive valuation multiples
P/SPrice/Sales ratio is 72x
6 Stock price has recently run up significantly
12M Rtn12 month market price return is 115%
7 Not cash flow generative
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -194%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -194%
8 Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -8.1%

Market Valuation & Key Metrics

NAMS Stock


Return vs. Risk


Price Returns Compared

 202020212022202320242025Total [1]
Returns
NAMS Return---2%130%51%228%
Peers Return-15%-9%-6%-3%-3%-16%-43%
S&P 500 Return16%27%-19%24%23%16%110%

Monthly Win Rates [3]
NAMS Win Rate--100%42%67%33% 
Peers Win Rate18%15%23%31%22%51% 
S&P 500 Win Rate58%75%42%67%75%67% 

Max Drawdowns [4]
NAMS Max Drawdown----45%0%-42% 
Peers Max Drawdown-20%-13%-14%-15%-30%-27% 
S&P 500 Max Drawdown-31%-1%-25%-1%-2%-15% 


[1] Cumulative total returns since the beginning of 2020
[2] Peers: VRTX, APM, BBOT, GDTC, HIND.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2025 data is for the year up to 10/30/2025 (YTD)

How Low Can It Go

Unique KeyEventNAMSS&P 500
2022 Inflation Shock2022 Inflation Shock  
2022 Inflation Shock% Loss% Loss-66.2%-25.4%
2022 Inflation Shock% Gain to Breakeven% Gain to Breakeven196.2%34.1%
2022 Inflation ShockTime to BreakevenTime to Breakeven86 days464 days

Compare to VRTX, APM, BBOT, GDTC, HIND


In The Past

NewAmsterdam Pharma's stock fell -66.2% during the 2022 Inflation Shock from a high on 1/30/2023. A -66.2% loss requires a 196.2% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth over time.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

About NewAmsterdam Pharma (NAMS)

Better Bets than NewAmsterdam Pharma (NAMS)

Trade Ideas

Select past ideas related to NAMS. For more, see Trefis Trade Ideas.

Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
ADMA_9302025_Dip_Buyer_ValueBuy09302025ADMAADMA BiologicsDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
5.9%5.9%-4.6%
REGN_9302025_Dip_Buyer_ValueBuy09302025REGNRegeneron PharmaceuticalsDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
16.1%16.1%-0.8%
HAE_9262025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG09262025HAEHaemoneticsDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
2.6%2.6%-0.1%
WAT_9192025_Monopoly_xInd_xCD_Getting_Cheaper09192025WATWatersMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
14.2%14.2%-4.3%
ISRG_9052025_Monopoly_xInd_xCD_Getting_Cheaper09052025ISRGIntuitive SurgicalMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
15.2%15.2%-8.0%
Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
ADMA_9302025_Dip_Buyer_ValueBuy09302025ADMAADMA BiologicsDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
5.9%5.9%-4.6%
REGN_9302025_Dip_Buyer_ValueBuy09302025REGNRegeneron PharmaceuticalsDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
16.1%16.1%-0.8%
HAE_9262025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG09262025HAEHaemoneticsDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
2.6%2.6%-0.1%
WAT_9192025_Monopoly_xInd_xCD_Getting_Cheaper09192025WATWatersMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
14.2%14.2%-4.3%
ISRG_9052025_Monopoly_xInd_xCD_Getting_Cheaper09052025ISRGIntuitive SurgicalMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
15.2%15.2%-8.0%

Recent Active Movers

Recent Active Movers

More From Trefis

Peer Comparisons for NewAmsterdam Pharma

Financials

NAMSVRTXAPMBBOTGDTCHINDMedian
NameNewAmste.Vertex P.Aptorum BridgeBi.CytoMed .Vyome  
Mkt Price38.72419.891.4712.002.155.588.79
Mkt Cap4.6107.8----56.2
Rev LTM6411,419-0--64
Op Inc LTM-175-199--93---175
FCF LTM-1243,500--60---60
FCF 3Y Avg-1,984----1,984
CFO LTM-1243,846--60---60
CFO 3Y Avg-2,324----2,324

Growth & Margins

NAMSVRTXAPMBBOTGDTCHINDMedian
NameNewAmste.Vertex P.Aptorum BridgeBi.CytoMed .Vyome  
Rev Chg LTM762.1%10.5%----386.3%
Rev Chg 3Y Avg-11.0%----11.0%
Rev Chg Q740.1%12.1%----376.1%
QoQ Delta Rev Chg LTM35.8%2.9%----19.3%
Op Mgn LTM-273.2%-1.7%-----137.5%
Op Mgn 3Y Avg-26.5%----26.5%
QoQ Delta Op Mgn LTM133.7%2.0%----67.9%
CFO/Rev LTM-193.9%33.7%-----80.1%
CFO/Rev 3Y Avg-22.5%----22.5%
FCF/Rev LTM-194.2%30.6%-----81.8%
FCF/Rev 3Y Avg-19.2%----19.2%

Valuation

NAMSVRTXAPMBBOTGDTCHINDMedian
NameNewAmste.Vertex P.Aptorum BridgeBi.CytoMed .Vyome  
Mkt Cap4.6107.8----56.2
P/S71.79.4----40.6
P/EBIT-19.124.5----2.7
P/E-27.729.6----1.0
P/CFO-37.028.0-----4.5
Total Yield-3.6%3.4%-----0.1%
Dividend Yield0.0%0.0%----0.0%
FCF Yield 3Y Avg-2.1%----2.1%
D/E0.00.0----0.0
Net D/E-0.2-0.0-----0.1

Returns

NAMSVRTXAPMBBOTGDTCHINDMedian
NameNewAmste.Vertex P.Aptorum BridgeBi.CytoMed .Vyome  
1M Rtn36.1%7.2%-27.2%3.6%8.0%7.7%7.5%
3M Rtn77.5%-8.1%-5.2%-14.4%-4.6%
6M Rtn93.3%-15.8%59.8%--6.5%-26.6%
12M Rtn115.1%-11.6%5.0%--3.4%-0.8%
3Y Rtn-34.6%-76.8%----21.1%
1M Excs Rtn30.2%2.2%-34.2%-1.9%5.3%-0.2%1.0%
3M Excs Rtn72.6%-18.5%-2.1%-8.1%-3.0%
6M Excs Rtn71.6%-37.6%38.0%--28.3%-4.9%
12M Excs Rtn85.3%-29.0%-17.8%--33.2%--23.4%
3Y Excs Rtn--41.0%-151.9%----96.5%

Financials

Price Behavior

Short Interest

Short Interest: As Of Date10152025
Short Interest: Shares Quantity6,855,986
Short Interest: % Change Since 9302025-10.3%
Average Daily Volume1,493,276
Days-to-Cover Short Interest4.59
Basic Shares Quantity118,556,492
Short % of Basic Shares5.8%

Earnings Returns History

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 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
8/6/20258.7%15.0%18.1%
5/8/20251.8%-0.9%6.4%
2/26/202510.2%20.2%26.2%
11/6/202413.7%29.3%-5.6%
8/7/2024-3.5%6.1%-0.2%
5/9/20240.3%-9.1%-11.4%
2/28/2024-2.5%-8.1%-6.3%
SUMMARY STATS   
# Positive543
# Negative234
Median Positive8.7%17.6%18.1%
Median Negative-3.0%-8.1%-6.0%
Max Positive13.7%29.3%26.2%
Max Negative-3.5%-9.1%-11.4%

SEC Filings

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Report DateFiling DateFiling
6302025806202510-Q 6/30/2025
3312025508202510-Q 3/31/2025
12312024226202510-K 12/31/2024
93020241106202410-Q 9/30/2024
6302024807202410-Q 6/30/2024
3312024508202410-Q 3/31/2024
12312023228202410-K 12/31/2023
630202380720236-K 6/30/2023
12312022331202320-F 12/31/2022
1231202110182022424B3 12/31/2021

Insider Activity

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