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CERo Therapeutics (CERO)


Market Price (10/31/2025): $0.125 | Market Cap: $61,010
Sector: Health Care | Industry: Biotechnology

CERo Therapeutics (CERO)


Market Price (10/31/2025): $0.125
Market Cap: $61,010
Sector: Health Care
Industry: Biotechnology

Investment Highlights Why It Matters Which of these 2 stories sounds closer for this stock?

1. Generates cash flow

The stock generated 4% or more of the share price (called cash flow yield), and shows moderate 10-15% or more growth.

2. Riding a trend

Think Tesla during the pandemic of 2020 when EVs were riding a cultural high, or Nvidia in the current AI boom, or even Figma. These companies don’t have enough yield, or, enough growth, or both - however - they are riding a trend. They have momentum. These can be more volatile - they don’t have the floor of strong cash flow


0 Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -5430%
Weak multi-year price returns
2Y Excs Rtn is -165%, 3Y Excs Rtn is -177%
Penny stock
Mkt Price is 0.1
1   Very low revenue
Rev LTMTotal Revenue or Sales, Last Twelve Months is 0
2   Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -20 Mil
3   Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -35245%
4   High stock price volatility
Vol 12M is 1794%
5   Significant short interest
Short Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 40%
0 Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -5430%
1 Weak multi-year price returns
2Y Excs Rtn is -165%, 3Y Excs Rtn is -177%
2 Penny stock
Mkt Price is 0.1
3 Very low revenue
Rev LTMTotal Revenue or Sales, Last Twelve Months is 0
4 Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -20 Mil
5 Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -35245%
6 High stock price volatility
Vol 12M is 1794%
7 Significant short interest
Short Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 40%

Market Valuation & Key Metrics

CERO Stock


Return vs. Risk


Price Returns Compared

 202020212022202320242025Total [1]
Returns
CERO Return--4%7%-99%-100%-100%
Peers Return-15%-9%-6%-3%-3%-16%-43%
S&P 500 Return16%27%-19%24%23%16%110%

Monthly Win Rates [3]
CERO Win Rate-0%92%75%25%11% 
Peers Win Rate18%15%23%31%22%51% 
S&P 500 Win Rate58%75%42%67%75%67% 

Max Drawdowns [4]
CERO Max Drawdown--0%0%-100%-100% 
Peers Max Drawdown-20%-13%-14%-15%-30%-27% 
S&P 500 Max Drawdown-31%-1%-25%-1%-2%-15% 


[1] Cumulative total returns since the beginning of 2020
[2] Peers: VRTX, APM, BBOT, GDTC, HIND.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2025 data is for the year up to 10/30/2025 (YTD)

How Low Can It Go

Unique KeyEventCEROS&P 500
2022 Inflation Shock2022 Inflation Shock  
2022 Inflation Shock% Loss% Loss-2.6%-25.4%
2022 Inflation Shock% Gain to Breakeven% Gain to Breakeven2.7%34.1%
2022 Inflation ShockTime to BreakevenTime to Breakeven209 days464 days

Compare to VRTX, APM, BBOT, GDTC, HIND


In The Past

CERo Therapeutics's stock fell -2.6% during the 2022 Inflation Shock from a high on 4/27/2023. A -2.6% loss requires a 2.7% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth over time.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

About CERo Therapeutics (CERO)

Better Bets than CERo Therapeutics (CERO)

Trade Ideas

Select past ideas related to CERO. For more, see Trefis Trade Ideas.

Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
ADMA_9302025_Dip_Buyer_ValueBuy09302025ADMAADMA BiologicsDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
5.9%5.9%-4.6%
REGN_9302025_Dip_Buyer_ValueBuy09302025REGNRegeneron PharmaceuticalsDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
16.1%16.1%-0.8%
HAE_9262025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG09262025HAEHaemoneticsDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
2.6%2.6%-0.1%
WAT_9192025_Monopoly_xInd_xCD_Getting_Cheaper09192025WATWatersMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
14.2%14.2%-4.3%
ISRG_9052025_Monopoly_xInd_xCD_Getting_Cheaper09052025ISRGIntuitive SurgicalMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
15.2%15.2%-8.0%
Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
ADMA_9302025_Dip_Buyer_ValueBuy09302025ADMAADMA BiologicsDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
5.9%5.9%-4.6%
REGN_9302025_Dip_Buyer_ValueBuy09302025REGNRegeneron PharmaceuticalsDip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
16.1%16.1%-0.8%
HAE_9262025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG09262025HAEHaemoneticsDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
2.6%2.6%-0.1%
WAT_9192025_Monopoly_xInd_xCD_Getting_Cheaper09192025WATWatersMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
14.2%14.2%-4.3%
ISRG_9052025_Monopoly_xInd_xCD_Getting_Cheaper09052025ISRGIntuitive SurgicalMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
15.2%15.2%-8.0%

Recent Active Movers

Recent Active Movers

More From Trefis

Peer Comparisons for CERo Therapeutics

Financials

CEROVRTXAPMBBOTGDTCHINDMedian
NameCERo The.Vertex P.Aptorum BridgeBi.CytoMed .Vyome  
Mkt Price0.10419.891.4712.002.155.583.87
Mkt Cap0.0107.8----53.9
Rev LTM011,419-0--0
Op Inc LTM-20-199--93---93
FCF LTM-3,500--60--1,720
FCF 3Y Avg-1,984----1,984
CFO LTM-3,846--60--1,893
CFO 3Y Avg-2,324----2,324

Growth & Margins

CEROVRTXAPMBBOTGDTCHINDMedian
NameCERo The.Vertex P.Aptorum BridgeBi.CytoMed .Vyome  
Rev Chg LTM-10.5%----10.5%
Rev Chg 3Y Avg-11.0%----11.0%
Rev Chg Q-12.1%----12.1%
QoQ Delta Rev Chg LTM-2.9%----2.9%
Op Mgn LTM--1.7%-----1.7%
Op Mgn 3Y Avg-26.5%----26.5%
QoQ Delta Op Mgn LTM-2.0%----2.0%
CFO/Rev LTM-33.7%----33.7%
CFO/Rev 3Y Avg-22.5%----22.5%
FCF/Rev LTM-30.6%----30.6%
FCF/Rev 3Y Avg-19.2%----19.2%

Valuation

CEROVRTXAPMBBOTGDTCHINDMedian
NameCERo The.Vertex P.Aptorum BridgeBi.CytoMed .Vyome  
Mkt Cap0.0107.8----53.9
P/S-9.4----9.4
P/EBIT-0.024.5----12.3
P/E-0.029.6----14.8
P/CFO-28.0----28.0
Total Yield-35,240.1%3.4%-----17,618.4%
Dividend Yield0.0%0.0%----0.0%
FCF Yield 3Y Avg-2.1%----2.1%
D/E23.60.0----11.8
Net D/E-54.3-0.0-----27.2

Returns

CEROVRTXAPMBBOTGDTCHINDMedian
NameCERo The.Vertex P.Aptorum BridgeBi.CytoMed .Vyome  
1M Rtn-98.1%7.2%-27.2%3.6%8.0%7.7%5.4%
3M Rtn-98.8%-8.1%-5.2%-14.4%--6.6%
6M Rtn-100.0%-15.8%59.8%--6.5%--11.2%
12M Rtn-100.0%-11.6%5.0%--3.4%--7.5%
3Y Rtn-100.0%34.6%-76.8%----76.8%
1M Excs Rtn-99.9%2.2%-34.2%-1.9%5.3%-0.2%-1.1%
3M Excs Rtn-108.1%-18.5%-2.1%-8.1%--10.3%
6M Excs Rtn-121.7%-37.6%38.0%--28.3%--32.9%
12M Excs Rtn-117.1%-29.0%-17.8%--33.2%--31.1%
3Y Excs Rtn-176.8%-41.0%-151.9%----151.9%

Financials

Price Behavior

Short Interest

Short Interest: As Of Date10152025
Short Interest: Shares Quantity192,892
Short Interest: % Change Since 9302025167.2%
Average Daily Volume392,912
Days-to-Cover Short Interest1
Basic Shares Quantity488,076
Short % of Basic Shares39.5%

SEC Filings

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Report DateFiling DateFiling
6302025822202510-Q 6/30/2025
3312025515202510-Q 3/31/2025
93020241119202410-Q 9/30/2024
6302024814202410-Q 6/30/2024
12312023415202510-K 12/31/2023
93020231120202410-Q/A 9/30/2023
123120228142023S-4/A 12/31/2022

Insider Activity

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 OwnerTitleFiling DateActionPriceSharesTransacted
Value
Value of
Held Shares
Form
0YK Bioventures Opportunities GP I, LLC12132024Sell0.081,343,801107,5041,409,489Form
1YK Bioventures Opportunities GP I, LLC12102024Sell0.121,236,874148,4252,566,069Form
2SLOAN STUART M11202024Sell0.10532,48655,5382,197,388Form
3YK Bioventures Opportunities GP I, LLC11142024Sell0.103,250,000325,0002,262,078Form