Tearsheet

Investment Highlights Why It Matters Which of these 2 stories sounds closer for this stock?

1. Generates cash flow

The stock generated 4% or more of the share price (called cash flow yield), and shows moderate 10-15% or more growth.

2. Riding a trend

Think Tesla during the pandemic of 2020 when EVs were riding a cultural high, or Nvidia in the current AI boom, or even Figma. These companies don’t have enough yield, or, enough growth, or both - however - they are riding a trend. They have momentum. These can be more volatile - they don’t have the floor of strong cash flow


0 Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -33%
Weak multi-year price returns
2Y Excs Rtn is -97%, 3Y Excs Rtn is -112%
Very low revenue
Rev LTMTotal Revenue or Sales, Last Twelve Months is 0
1 Megatrend and thematic drivers
Megatrends include Precision Medicine, and Health & Wellness Trends. Themes include Biopharmaceutical R&D, Targeted Therapies, Show more.
  Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -99 Mil
2   Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -57%
3   Key risks
CYBN key risks include [1] its viability hinging entirely on the clinical and regulatory success of its lead drug candidates, Show more.
0 Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -33%
1 Megatrend and thematic drivers
Megatrends include Precision Medicine, and Health & Wellness Trends. Themes include Biopharmaceutical R&D, Targeted Therapies, Show more.
2 Weak multi-year price returns
2Y Excs Rtn is -97%, 3Y Excs Rtn is -112%
3 Very low revenue
Rev LTMTotal Revenue or Sales, Last Twelve Months is 0
4 Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -99 Mil
5 Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -57%
6 Key risks
CYBN key risks include [1] its viability hinging entirely on the clinical and regulatory success of its lead drug candidates, Show more.

Valuation, Metrics & Events

CYBN Stock


Why The Stock Moved


Qualitative Assessment

AI Generated Analysis | Feedback

Between August 31, 2025, and December 18, 2025, Cybin (CYBN) experienced a stock movement of approximately -9.2% due to several key factors:

1. Leadership Transition with CEO Doug Drysdale's Departure: In early September 2025, Cybin announced that CEO Doug Drysdale had stepped down, with co-founder Eric So appointed as interim CEO. This unexpected leadership change introduced uncertainty and contributed to a downturn in market sentiment.

2. Delays in Clinical Trial Timelines: Investors' confidence was negatively impacted by delays in Cybin's clinical trial progress. Notably, the anticipated topline data readout for the CYB004 Phase 2 study was pushed from the first quarter of 2025 to the first quarter of 2026. Additionally, the initiation of the EMBRACE study, a pivotal component of the Phase 3 CYB003 program, while approved in various regions by August 2025, was still only expected to initiate enrollment in the fourth quarter of 2025.

Show more

Stock Movement Drivers

Return vs. Risk


Price Returns Compared

 202020212022202320242025Total [1]
Returns
CYBN Return0%513%-75%38%-43%-24%-10%
Peers Return2093%-36%-87%42%1%421%1273%
S&P 500 Return16%27%-19%24%23%14%108%

Monthly Win Rates [3]
CYBN Win Rate0%8%25%50%33%50% 
Peers Win Rate42%42%42%54%46%54% 
S&P 500 Win Rate58%75%42%67%75%73% 

Max Drawdowns [4]
CYBN Max Drawdown0%0%-78%-22%-51%-43% 
Peers Max Drawdown-25%-45%-90%-18%-47%-41% 
S&P 500 Max Drawdown-31%-1%-25%-1%-2%-15% 


[1] Cumulative total returns since the beginning of 2020
[2] Peers: MNMD, RLMD.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2025 data is for the year up to 12/17/2025 (YTD)

How Low Can It Go

Unique KeyEventCYBNS&P 500
2022 Inflation Shock2022 Inflation Shock  
2022 Inflation Shock% Loss% Loss-91.7%-25.4%
2022 Inflation Shock% Gain to Breakeven% Gain to Breakeven1106.9%34.1%
2022 Inflation ShockTime to BreakevenTime to BreakevenNot Fully Recovered days464 days

Compare to VRTX, AIXC, ALPS, BBOT, EVMN


In The Past

Cybin's stock fell -91.7% during the 2022 Inflation Shock from a high on 8/31/2021. A -91.7% loss requires a 1106.9% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth over time.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

About Cybin (CYBN)

Better Bets than Cybin (CYBN)

Trade Ideas

Select past ideas related to CYBN. For more, see Trefis Trade Ideas.

Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
CRL_11142025_Dip_Buyer_FCFYield11142025CRLCharles River Laboratories InternationalDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
16.3%16.3%-3.7%
GDRX_11142025_Dip_Buyer_High_CFO_Margins_ExInd_DE11142025GDRXGoodRxDip BuyDB | CFO/Rev | Low D/EDip Buy with High Cash Flow Margins
Buying dips for companies with significant cash flows from operations and reasonable debt / market cap
-7.1%-7.1%-11.8%
ASTH_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025ASTHAstrana HealthDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
3.6%3.6%-5.5%
SGRY_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025SGRYSurgery PartnersDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
1.6%1.6%-1.4%
TFX_11072025_Dip_Buyer_FCFYield11072025TFXTeleflexDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
14.1%14.1%-5.1%
Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
CRL_11142025_Dip_Buyer_FCFYield11142025CRLCharles River Laboratories InternationalDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
16.3%16.3%-3.7%
GDRX_11142025_Dip_Buyer_High_CFO_Margins_ExInd_DE11142025GDRXGoodRxDip BuyDB | CFO/Rev | Low D/EDip Buy with High Cash Flow Margins
Buying dips for companies with significant cash flows from operations and reasonable debt / market cap
-7.1%-7.1%-11.8%
ASTH_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025ASTHAstrana HealthDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
3.6%3.6%-5.5%
SGRY_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025SGRYSurgery PartnersDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
1.6%1.6%-1.4%
TFX_11072025_Dip_Buyer_FCFYield11072025TFXTeleflexDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
14.1%14.1%-5.1%

Recent Active Movers

Recent Active Movers

More From Trefis

Peer Comparisons for Cybin

Peers to compare with:

Financials

CYBNMNMDRLMDMedian
NameCybin Mind Med.Relmada . 
Mkt Price6.7912.134.016.79
Mkt Cap0.21.00.10.2
Rev LTM0000
Op Inc LTM-99-151-58-99
FCF LTM-97-114-40-97
FCF 3Y Avg-68-82-57-68
CFO LTM-96-114-40-96
CFO 3Y Avg-67-82-57-67

Growth & Margins

CYBNMNMDRLMDMedian
NameCybin Mind Med.Relmada . 
Rev Chg LTM----
Rev Chg 3Y Avg----
Rev Chg Q----
QoQ Delta Rev Chg LTM----
Op Mgn LTM----
Op Mgn 3Y Avg----
QoQ Delta Op Mgn LTM----
CFO/Rev LTM----
CFO/Rev 3Y Avg----
FCF/Rev LTM----
FCF/Rev 3Y Avg----

Valuation

CYBNMNMDRLMDMedian
NameCybin Mind Med.Relmada . 
Mkt Cap0.21.00.10.2
P/S----
P/EBIT-1.7-6.2--3.9
P/E-1.9-6.0-1.2-1.9
P/CFO-1.7-8.9-1.7-1.7
Total Yield-53.1%-16.6%-84.2%-53.1%
Dividend Yield0.0%0.0%0.0%0.0%
FCF Yield 3Y Avg-45.5%-24.5%--35.0%
D/E0.20.0-0.1
Net D/E-0.3-0.2--0.3

Returns

CYBNMNMDRLMDMedian
NameCybin Mind Med.Relmada . 
1M Rtn11.9%7.0%1.0%7.0%
3M Rtn13.2%26.8%165.6%26.8%
6M Rtn-14.1%71.1%472.9%71.1%
12M Rtn-28.3%62.2%1,008.7%62.2%
3Y Rtn-32.5%346.0%19.0%19.0%
1M Excs Rtn11.1%6.2%0.3%6.2%
3M Excs Rtn11.8%26.6%141.7%26.6%
6M Excs Rtn-26.4%58.7%460.6%58.7%
12M Excs Rtn-41.7%58.3%981.6%58.3%
3Y Excs Rtn-112.1%287.6%-50.1%-50.1%

Financials

Segment Financials

Assets by Segment

$ Mil2025202420232022
Single Segment224406773
Total224406773


Price Behavior

Short Interest

Short Interest: As Of Date11282025
Short Interest: Shares Quantity2,168,206
Short Interest: % Change Since 11152025-2.6%
Average Daily Volume543,562
Days-to-Cover Short Interest3.99
Basic Shares Quantity24,205,871
Short % of Basic Shares9.0%

SEC Filings

Expand for More

Report DateFiling DateFiling
9302025111320256-K 9/30/2025
630202581420256-K 6/30/2025
3312025701202540-F 3/31/2025
1231202421120256-K 12/31/2024
9302024111320246-K 9/30/2024
630202480820246-K 6/30/2024
3312024626202440-F 3/31/2024
1231202321420246-K 12/31/2023
9302023111520236-K 9/30/2023
630202381420236-K 6/30/2023
3312023627202340-F 3/31/2023
1231202221420236-K 12/31/2022
9302022111520226-K 9/30/2022
630202280820226-K 6/30/2022
3312022622202240-F 3/31/2022
1231202121020226-K 12/31/2021