Cybin (CYBN)
Market Price (12/18/2025): $6.76 | Market Cap: $163.6 MilSector: Health Care | Industry: Biotechnology
Cybin (CYBN)
Market Price (12/18/2025): $6.76Market Cap: $163.6 MilSector: Health CareIndustry: Biotechnology
Investment Highlights
Why It Matters
Which of these 2 stories sounds closer for this stock?
1. Generates cash flow
The stock generated 4% or more of the share price (called cash flow yield), and shows moderate 10-15% or more growth.
2. Riding a trend
Think Tesla during the pandemic of 2020 when EVs were riding a cultural high, or Nvidia in the current AI boom, or even Figma. These companies don’t have enough yield, or, enough growth, or both - however - they are riding a trend. They have momentum. These can be more volatile - they don’t have the floor of strong cash flow
| Cash is significant % of market capNet D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -33% | Weak multi-year price returns2Y Excs Rtn is -97%, 3Y Excs Rtn is -112% | Very low revenueRev LTMTotal Revenue or Sales, Last Twelve Months is 0 |
| Megatrend and thematic driversMegatrends include Precision Medicine, and Health & Wellness Trends. Themes include Biopharmaceutical R&D, Targeted Therapies, Show more. | Not profitable at operating income levelOp Inc LTMOperating Income, Last Twelve Months is -99 Mil | |
| Yield minus risk free rate is negativeERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -57% | ||
| Key risksCYBN key risks include [1] its viability hinging entirely on the clinical and regulatory success of its lead drug candidates, Show more. |
| Cash is significant % of market capNet D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -33% |
| Megatrend and thematic driversMegatrends include Precision Medicine, and Health & Wellness Trends. Themes include Biopharmaceutical R&D, Targeted Therapies, Show more. |
| Weak multi-year price returns2Y Excs Rtn is -97%, 3Y Excs Rtn is -112% |
| Very low revenueRev LTMTotal Revenue or Sales, Last Twelve Months is 0 |
| Not profitable at operating income levelOp Inc LTMOperating Income, Last Twelve Months is -99 Mil |
| Yield minus risk free rate is negativeERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -57% |
| Key risksCYBN key risks include [1] its viability hinging entirely on the clinical and regulatory success of its lead drug candidates, Show more. |
Valuation, Metrics & Events
CYBN Stock
Why The Stock Moved
Qualitative Assessment
AI Generated Analysis | Feedback
Between August 31, 2025, and December 18, 2025, Cybin (CYBN) experienced a stock movement of approximately -9.2% due to several key factors:
1. Leadership Transition with CEO Doug Drysdale's Departure: In early September 2025, Cybin announced that CEO Doug Drysdale had stepped down, with co-founder Eric So appointed as interim CEO. This unexpected leadership change introduced uncertainty and contributed to a downturn in market sentiment.
2. Delays in Clinical Trial Timelines: Investors' confidence was negatively impacted by delays in Cybin's clinical trial progress. Notably, the anticipated topline data readout for the CYB004 Phase 2 study was pushed from the first quarter of 2025 to the first quarter of 2026. Additionally, the initiation of the EMBRACE study, a pivotal component of the Phase 3 CYB003 program, while approved in various regions by August 2025, was still only expected to initiate enrollment in the fourth quarter of 2025.
Stock Movement Drivers
Return vs. Risk
Price Returns Compared
| 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total [1] | |
|---|---|---|---|---|---|---|---|
| Returns | |||||||
| CYBN Return | 0% | 513% | -75% | 38% | -43% | -24% | -10% |
| Peers Return | 2093% | -36% | -87% | 42% | 1% | 421% | 1273% |
| S&P 500 Return | 16% | 27% | -19% | 24% | 23% | 14% | 108% |
Monthly Win Rates [3] | |||||||
| CYBN Win Rate | 0% | 8% | 25% | 50% | 33% | 50% | |
| Peers Win Rate | 42% | 42% | 42% | 54% | 46% | 54% | |
| S&P 500 Win Rate | 58% | 75% | 42% | 67% | 75% | 73% | |
Max Drawdowns [4] | |||||||
| CYBN Max Drawdown | 0% | 0% | -78% | -22% | -51% | -43% | |
| Peers Max Drawdown | -25% | -45% | -90% | -18% | -47% | -41% | |
| S&P 500 Max Drawdown | -31% | -1% | -25% | -1% | -2% | -15% | |
[1] Cumulative total returns since the beginning of 2020
[2] Peers: MNMD, RLMD.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2025 data is for the year up to 12/17/2025 (YTD)
How Low Can It Go
| Event | CYBN | S&P 500 |
|---|---|---|
| 2022 Inflation Shock | ||
| % Loss | -91.7% | -25.4% |
| % Gain to Breakeven | 1106.9% | 34.1% |
| Time to Breakeven | Not Fully Recovered days | 464 days |
Compare to VRTX, AIXC, ALPS, BBOT, EVMN
In The Past
Cybin's stock fell -91.7% during the 2022 Inflation Shock from a high on 8/31/2021. A -91.7% loss requires a 1106.9% gain to breakeven.
Preserve Wealth
Limiting losses and compounding gains is essential to preserving wealth over time.
Asset Allocation
Actively managed asset allocation strategies protect wealth. Learn more.
Trade Ideas
Select past ideas related to CYBN. For more, see Trefis Trade Ideas.
| Date | Ticker | Company | Category | Trade Strategy | 6M Fwd Rtn | 12M Fwd Rtn | 12M Max DD |
|---|---|---|---|---|---|---|---|
| 11142025 | CRL | Charles River Laboratories International | Dip Buy | DB | FCFY OPMDip Buy with High FCF Yield and High MarginBuying dips for companies with high FCF yield and meaningfully high operating margin | 16.3% | 16.3% | -3.7% |
| 11142025 | GDRX | GoodRx | Dip Buy | DB | CFO/Rev | Low D/EDip Buy with High Cash Flow MarginsBuying dips for companies with significant cash flows from operations and reasonable debt / market cap | -7.1% | -7.1% | -11.8% |
| 11142025 | ASTH | Astrana Health | Dip Buy | DB | FCF Yield | Low D/EDip Buy with High Free Cash Flow YieldBuying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap | 3.6% | 3.6% | -5.5% |
| 11142025 | SGRY | Surgery Partners | Dip Buy | DB | FCF Yield | Low D/EDip Buy with High Free Cash Flow YieldBuying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap | 1.6% | 1.6% | -1.4% |
| 11072025 | TFX | Teleflex | Dip Buy | DB | FCFY OPMDip Buy with High FCF Yield and High MarginBuying dips for companies with high FCF yield and meaningfully high operating margin | 14.1% | 14.1% | -5.1% |
| Date | Ticker | Company | Category | Trade Strategy | 6M Fwd Rtn | 12M Fwd Rtn | 12M Max DD |
|---|---|---|---|---|---|---|---|
| 11142025 | CRL | Charles River Laboratories International | Dip Buy | DB | FCFY OPMDip Buy with High FCF Yield and High MarginBuying dips for companies with high FCF yield and meaningfully high operating margin | 16.3% | 16.3% | -3.7% |
| 11142025 | GDRX | GoodRx | Dip Buy | DB | CFO/Rev | Low D/EDip Buy with High Cash Flow MarginsBuying dips for companies with significant cash flows from operations and reasonable debt / market cap | -7.1% | -7.1% | -11.8% |
| 11142025 | ASTH | Astrana Health | Dip Buy | DB | FCF Yield | Low D/EDip Buy with High Free Cash Flow YieldBuying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap | 3.6% | 3.6% | -5.5% |
| 11142025 | SGRY | Surgery Partners | Dip Buy | DB | FCF Yield | Low D/EDip Buy with High Free Cash Flow YieldBuying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap | 1.6% | 1.6% | -1.4% |
| 11072025 | TFX | Teleflex | Dip Buy | DB | FCFY OPMDip Buy with High FCF Yield and High MarginBuying dips for companies with high FCF yield and meaningfully high operating margin | 14.1% | 14.1% | -5.1% |
Research & Analysis
Invest in Strategies
Wealth Management
Peer Comparisons for Cybin
| Peers to compare with: |
Financials
| Median | |
|---|---|
| Name | |
| Mkt Price | 6.79 |
| Mkt Cap | 0.2 |
| Rev LTM | 0 |
| Op Inc LTM | -99 |
| FCF LTM | -97 |
| FCF 3Y Avg | -68 |
| CFO LTM | -96 |
| CFO 3Y Avg | -67 |
Growth & Margins
| Median | |
|---|---|
| Name | |
| Rev Chg LTM | - |
| Rev Chg 3Y Avg | - |
| Rev Chg Q | - |
| QoQ Delta Rev Chg LTM | - |
| Op Mgn LTM | - |
| Op Mgn 3Y Avg | - |
| QoQ Delta Op Mgn LTM | - |
| CFO/Rev LTM | - |
| CFO/Rev 3Y Avg | - |
| FCF/Rev LTM | - |
| FCF/Rev 3Y Avg | - |
Valuation
| Median | |
|---|---|
| Name | |
| Mkt Cap | 0.2 |
| P/S | - |
| P/EBIT | -3.9 |
| P/E | -1.9 |
| P/CFO | -1.7 |
| Total Yield | -53.1% |
| Dividend Yield | 0.0% |
| FCF Yield 3Y Avg | -35.0% |
| D/E | 0.1 |
| Net D/E | -0.3 |
Returns
| Median | |
|---|---|
| Name | |
| 1M Rtn | 7.0% |
| 3M Rtn | 26.8% |
| 6M Rtn | 71.1% |
| 12M Rtn | 62.2% |
| 3Y Rtn | 19.0% |
| 1M Excs Rtn | 6.2% |
| 3M Excs Rtn | 26.6% |
| 6M Excs Rtn | 58.7% |
| 12M Excs Rtn | 58.3% |
| 3Y Excs Rtn | -50.1% |
SEC Filings
Expand for More| Report Date | Filing Date | Filing |
|---|---|---|
| 9302025 | 11132025 | 6-K 9/30/2025 |
| 6302025 | 8142025 | 6-K 6/30/2025 |
| 3312025 | 7012025 | 40-F 3/31/2025 |
| 12312024 | 2112025 | 6-K 12/31/2024 |
| 9302024 | 11132024 | 6-K 9/30/2024 |
| 6302024 | 8082024 | 6-K 6/30/2024 |
| 3312024 | 6262024 | 40-F 3/31/2024 |
| 12312023 | 2142024 | 6-K 12/31/2023 |
| 9302023 | 11152023 | 6-K 9/30/2023 |
| 6302023 | 8142023 | 6-K 6/30/2023 |
| 3312023 | 6272023 | 40-F 3/31/2023 |
| 12312022 | 2142023 | 6-K 12/31/2022 |
| 9302022 | 11152022 | 6-K 9/30/2022 |
| 6302022 | 8082022 | 6-K 6/30/2022 |
| 3312022 | 6222022 | 40-F 3/31/2022 |
| 12312021 | 2102022 | 6-K 12/31/2021 |
Industry Resources
External Quote Links
| Y Finance | Barrons |
| TradingView | Morningstar |
| SeekingAlpha | ValueLine |
| Motley Fool | Robinhood |
| CNBC | Etrade |
| MarketWatch | Unusual Whales |
| YCharts | Perplexity Finance |
| FinViz |