Acrivon Therapeutics (ACRV)


Market Price (8/31/2026): $2.1 | Market Cap: $87.9 MilSector: Health Care | Industry: Biotechnology

Acrivon Therapeutics (ACRV)


Market Price (8/31/2026): $2.1
Market Cap: $87.9 Mil
Sector: Health Care
Industry: Biotechnology

Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.

0

Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -102%

Megatrend and thematic drivers
Megatrends include Precision Medicine, and Aging Population & Chronic Disease. Themes include Targeted Therapies, Personalized Diagnostics, Show more.

Weak multi-year price returns
2Y Excs Rtn is -115%, 3Y Excs Rtn is -156%

Very low revenue
Rev LTMTotal Revenue or Sales, Last Twelve Months is 0

Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -78 Mil

Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -91%

Key risks
ACRV key risks include [1] its critical dependence on the clinical trial success and regulatory approval of its lead candidates, Show more.

0 Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -102%
1 Megatrend and thematic drivers
Megatrends include Precision Medicine, and Aging Population & Chronic Disease. Themes include Targeted Therapies, Personalized Diagnostics, Show more.
2 Weak multi-year price returns
2Y Excs Rtn is -115%, 3Y Excs Rtn is -156%
3 Very low revenue
Rev LTMTotal Revenue or Sales, Last Twelve Months is 0
4 Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -78 Mil
5 Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -91%
6 Key risks
ACRV key risks include [1] its critical dependence on the clinical trial success and regulatory approval of its lead candidates, Show more.

ACRV in ETFs

Weight = ACRV's share of each fund

VTI0.00%

Valuation & Metrics

Price Chart

Why The Stock Moved

Qualitative Assessment

AI Analysis | Feedback

Updated on 8/26/2026

Acrivon Therapeutics (ACRV) stock has gained about 10% since 4/30/2026 because of the following key factors:

1. Positive Clinical Trial Progress for ACR-2316.

Acrivon Therapeutics announced in August 2026 the advancement of ACR-2316, a WEE1/PKMYT1 inhibitor, into the randomized dose expansion portion of its Phase 1/2 study. This progression was supported by a favorable safety profile and durable single-agent clinical activity, including partial responses in lung and endometrial cancer patients, with some heavily pretreated lung cancer subjects remaining on treatment for over one year.

2. Strong Fiscal Q2 2026 Earnings Beat and Extended Cash Runway.

On August 12, 2026, Acrivon Therapeutics reported its fiscal Q2 2026 financial results, with an earnings per share (EPS) of -$0.43, exceeding analysts' consensus estimates of -$0.50 by $0.07. The company also highlighted its cash, cash equivalents, and marketable securities totaling $90.0 million as of June 30, 2026 (the end of fiscal Q2 2026), which is projected to fund operations into fiscal Q4 2027, thereby extending its financial runway.

Show more
Updated on 8/26/2026

Acrivon Therapeutics (ACRV) stock has gained about 10% since 4/30/2026 because of the following key factors:

1. Positive Clinical Trial Progress for ACR-2316.

Acrivon Therapeutics announced in August 2026 the advancement of ACR-2316, a WEE1/PKMYT1 inhibitor, into the randomized dose expansion portion of its Phase 1/2 study. This progression was supported by a favorable safety profile and durable single-agent clinical activity, including partial responses in lung and endometrial cancer patients, with some heavily pretreated lung cancer subjects remaining on treatment for over one year.

2. Strong Fiscal Q2 2026 Earnings Beat and Extended Cash Runway.

On August 12, 2026, Acrivon Therapeutics reported its fiscal Q2 2026 financial results, with an earnings per share (EPS) of -$0.43, exceeding analysts' consensus estimates of -$0.50 by $0.07. The company also highlighted its cash, cash equivalents, and marketable securities totaling $90.0 million as of June 30, 2026 (the end of fiscal Q2 2026), which is projected to fund operations into fiscal Q4 2027, thereby extending its financial runway.

3. Encouraging Clinical Data for ACR-368 and Anticipated Near-Term Catalysts.

The fiscal Q1 2026 financial report on May 13, 2026, revealed compelling interim Phase 2b data for ACR-368, demonstrating a 52% confirmed overall response rate in serous endometrial cancer subjects. The company also reiterated its plans for a prespecified interim analysis of the registrational-intent ACR-368 Phase 2b study in the second half of 2026, acting as a significant near-term clinical catalyst.

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Stock Movement Drivers

Fundamental Drivers

The 11.4% change in ACRV stock from 4/30/2026 to 8/30/2026 was primarily driven by a 0.0% change in the company's Total Revenues ($ Mil).
(LTM values as of)43020268302026Change
Stock Price ($)1.852.0611.4%
Change Contribution By: 
Total Revenues ($ Mil)000.0%
P/S Multiple0.0%
Shares Outstanding (Mil)3942-7.6%
Cumulative Contribution0.0%

LTM = Last Twelve Months as of date shown

Market Drivers

4/30/2026 to 8/30/2026
ReturnCorrelation
ACRV11.4% 
Market (SPY)7.1%31.5%
Sector (XLV)17.2%9.5%

Fundamental Drivers

The 15.1% change in ACRV stock from 1/31/2026 to 8/30/2026 was primarily driven by a 0.0% change in the company's Total Revenues ($ Mil).
(LTM values as of)13120268302026Change
Stock Price ($)1.792.0615.1%
Change Contribution By: 
Total Revenues ($ Mil)000.0%
P/S Multiple0.0%
Shares Outstanding (Mil)3942-7.8%
Cumulative Contribution0.0%

LTM = Last Twelve Months as of date shown

Market Drivers

1/31/2026 to 8/30/2026
ReturnCorrelation
ACRV15.1% 
Market (SPY)11.5%37.1%
Sector (XLV)11.1%12.0%

Fundamental Drivers

The 60.9% change in ACRV stock from 7/31/2025 to 8/30/2026 was primarily driven by a 0.0% change in the company's Total Revenues ($ Mil).
(LTM values as of)73120258302026Change
Stock Price ($)1.282.0660.9%
Change Contribution By: 
Total Revenues ($ Mil)000.0%
P/S Multiple0.0%
Shares Outstanding (Mil)3842-8.3%
Cumulative Contribution0.0%

LTM = Last Twelve Months as of date shown

Market Drivers

7/31/2025 to 8/30/2026
ReturnCorrelation
ACRV60.9% 
Market (SPY)22.7%27.0%
Sector (XLV)32.9%17.1%

Fundamental Drivers

The -83.4% change in ACRV stock from 7/31/2023 to 8/30/2026 was primarily driven by a -69.1% change in the company's Shares Outstanding (Mil).
(LTM values as of)73120238302026Change
Stock Price ($)12.442.06-83.4%
Change Contribution By: 
Total Revenues ($ Mil)00.0%
P/S Multiple0.0%
Shares Outstanding (Mil)1342-69.1%
Cumulative Contribution0.0%

LTM = Last Twelve Months as of date shown

Market Drivers

7/31/2023 to 8/30/2026
ReturnCorrelation
ACRV-83.4% 
Market (SPY)74.0%25.1%
Sector (XLV)33.6%20.5%

Return vs. Risk

Price Returns Compared

 202120222023202420252026Total [1]
Returns
ACRV Return--31%-57%22%-60%-11%-87%
Peers Return6%-56%27%-44%19%92%-25%
S&P 500 Return27%-19%24%23%16%13%106%

Monthly Win Rates [3]
ACRV Win Rate-0%33%50%67%38% 
Peers Win Rate50%33%50%37%43%55% 
S&P 500 Win Rate75%42%67%75%67%50% 

Max Drawdowns [4]
ACRV Max Drawdown---84%-49%-85%-57% 
Peers Max Drawdown-48%-78%-60%-68%-65%-38% 
S&P 500 Max Drawdown-5%-25%-10%-8%-19%-9% 


[1] Cumulative total returns since the beginning of 2021
[2] Peers: ZNTL, APRE, IDYA, TNGX, ORIC.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 8/28/2026 (YTD)

About Acrivon Therapeutics (ACRV)

Acrivon Therapeutics (ACRV) is a clinical-stage biopharmaceutical company dedicated to developing precision oncology medicines. The company distinguishes itself by moving beyond traditional genomics-based patient selection methods, which often target a small percentage of cancer patients. Instead, Acrivon employs its proprietary proteomics-based platform, Acrivon Predictive Precision Proteomics (AP3), to create drug-specific OncoSignature companion diagnostics. This innovative platform directly measures critical tumor-driving proteins to identify patients whose tumors are predicted to be most sensitive to a specific medicine, thereby expanding the potential treatable population across a broader range of cancers.

The company's lead product candidate is ACR-368 (also known as prexasertib), a selective small molecule inhibitor targeting CHK1 and CHK2. ACR-368 is currently advancing in a potentially registrational Phase 2 trial under an FDA master protocol, initially focusing on patients with platinum-resistant ovarian, endometrial, or bladder cancer. Patients in this trial are stratified for treatment based on their OncoSignature-predicted sensitivity to ACR-368. Acrivon also plans to study ACR-368 in additional indications such as HPV+ squamous cell carcinomas, building on demonstrated clinical activity and OncoSignature-based predictions of sensitivity.

In addition to ACR-368, Acrivon is developing a preclinical pipeline of internally discovered programs targeting key nodes in DNA Damage Response and cell cycle regulation pathways, including WEE1 and PKMYT1. By leveraging its AP3 platform, Acrivon aims to significantly accelerate drug development, increase the probability of successful treatment outcomes, and ultimately address a much larger percentage of solid tumors for which genetics-based approaches have been insufficient to identify patient responders.

AI Analysis | Feedback

Here are 1-3 brief analogies for Acrivon Therapeutics:
  • Acrivon Therapeutics is like 23andMe for cancer treatment, but instead of using DNA to understand inherited risks, they use protein analysis to precisely match patients with the right drugs for their tumor.
  • Acrivon is like Waze for cancer drug development, using real-time molecular insights (proteins) to find the most efficient path for a drug to reach the right patients, rather than relying on older, static maps (genetics).

AI Analysis | Feedback

  • ACR-368 (Prexasertib): A clinical-stage small molecule inhibitor targeting CHK1 and CHK2, currently in a potentially registrational Phase 2 trial for various solid tumors.
  • Acrivon Predictive Precision Proteomics (AP3) Platform: A proprietary proteomics-based platform used to identify patient responders for oncology drug candidates and create drug-specific OncoSignature companion diagnostics.

AI Analysis | Feedback

As a clinical-stage biopharmaceutical company, Acrivon Therapeutics (ACRV) is currently focused on the development of precision oncology medicines and companion diagnostics, advancing its lead candidate, ACR-368, through Phase 2 clinical trials. At this stage of development, the company does not have commercial products on the market.

Therefore, Acrivon Therapeutics does not currently have major customers that purchase its products or services.

AI Analysis | Feedback

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The key risks to Acrivon Therapeutics' business are:

  1. Clinical Trial Success and Regulatory Approval of Lead Drug Candidate (ACR-368): Acrivon is a clinical-stage biopharmaceutical company, and the success of its lead candidate, ACR-368, in its ongoing "potentially registrational Phase 2 trial" is paramount. There is inherent risk in drug development, and failure to achieve favorable results in clinical trials or to obtain regulatory approval from bodies like the FDA would significantly impact the company's ability to commercialize its primary asset.
  2. Regulatory Approval and Efficacy of the AP3 Platform and OncoSignature Companion Diagnostics: Acrivon's core strategy relies on its proprietary proteomics-based patient responder identification platform (AP3) and its drug-specific OncoSignature companion diagnostics. The company explicitly states that its "ACR-368 OncoSignature test... has not yet obtained regulatory approval." The successful development, validation, and regulatory approval of this companion diagnostic are critical to its precision medicine approach and its ability to identify patient responders, which it believes will increase overall response rates and accelerate clinical development. Failure to secure regulatory approval for this platform or if it does not perform as anticipated in identifying sensitive patients, would undermine its entire business model and pipeline.

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The primary clear emerging threat for Acrivon Therapeutics is the regulatory approval and prospective clinical validation of its proprietary proteomics-based patient responder identification platform, Acrivon Predictive Precision Proteomics (AP3), and its associated OncoSignature companion diagnostic. The company explicitly states that the "ACR-368 OncoSignature test, which has not yet obtained regulatory approval." The success of their lead candidate, ACR-368, in its potentially registrational Phase 2 trial is contingent upon this OncoSignature test successfully identifying patient responders and receiving regulatory approval. A failure to secure regulatory approval for the diagnostic, or if the AP3 platform and OncoSignature test fail to demonstrate robust prospective predictive power and patient enrichment in the ongoing registrational-intent clinical trials, would undermine Acrivon Therapeutics' core precision oncology strategy and its ability to bring its drug candidates to market as intended.

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AI Analysis | Feedback

Here are 3-5 expected drivers of future revenue growth for Acrivon Therapeutics (ACRV) over the next 2-3 years:

  1. Advancement and potential regulatory approval of ACR-368 (prexasertib) for initial indications: Acrivon is currently advancing its lead candidate, ACR-368, in a potentially registrational Phase 2 trial for patients with platinum-resistant ovarian, endometrial, or bladder cancer. Successful completion of this trial and subsequent regulatory approval would be a primary driver of revenue growth as the company could begin commercializing the drug in these high-unmet-need indications.
  2. Expansion of ACR-368 into additional tumor types: Beyond its initial registrational trial, Acrivon plans to study ACR-368 in additional indications, such as human papilloma virus positive (HPV+) squamous cell carcinomas, including head and neck (SCCHN), anal, and cervical cancer. Successful clinical development and eventual approval in these expanded markets would significantly broaden the patient population and potential revenue streams for ACR-368.
  3. Commercialization and adoption of the proprietary OncoSignature companion diagnostic: Integral to Acrivon's strategy is its proprietary proteomics-based patient responder identification platform, AP3, which enables the creation of drug-specific OncoSignature companion diagnostics. The successful development, regulatory approval, and widespread adoption of the ACR-368 OncoSignature test are crucial for identifying patient responders and maximizing the efficacy and market potential of ACR-368, indirectly driving drug revenue and potentially generating revenue from the diagnostic itself.
  4. Strategic partnerships and collaborations: As Acrivon progresses its lead candidate ACR-368 and its innovative AP3 platform, the company may pursue strategic partnerships or collaborations. These could involve licensing agreements for specific regions, co-development deals, or partnerships to apply the AP3 platform to other drug candidates, generating revenue through upfront payments, milestone achievements, and royalties.

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Share Issuance

  • Acrivon Therapeutics priced its initial public offering on November 14, 2022, offering 7,550,000 shares of common stock at a price of $12.50 per share.
  • Concurrently with the IPO in November 2022, the company sold an additional 400,000 shares of common stock to an existing stockholder, Chione Limited, through a private placement. The gross proceeds from the IPO and this concurrent private placement were approximately $99.4 million.
  • In April 2024, Acrivon completed a private investment in public equity (PIPE) financing, issuing 8,235,000 shares of common stock at $8.50 per share and pre-funded warrants for up to 7,060,000 shares at $8.499 per warrant, raising approximately $130 million in gross proceeds.

Inbound Investments

  • Prior to its IPO in November 2022, Acrivon Therapeutics secured $100 million in an oversubscribed Series B financing round in November 2021.
  • The company completed a private investment in public equity (PIPE) financing in April 2024, with new and existing accredited investors providing approximately $130 million in gross proceeds.

Capital Expenditures

  • Acrivon Therapeutics invested $899K in capital expenditures in Q3 2025, primarily funding long-term assets and infrastructure.
  • Capital expenditures for the 12 months prior to Q3 2025 amounted to $2.28 million.
  • The company anticipates that its cash, cash equivalents, and investments are sufficient to fund operating expenses and capital expenditure requirements into the second quarter of 2027.

Peer Outperformance in Biotechnology

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Share of Biotechnology constituents that ACRV has outperformed, by holding period. Peers without a full price history over a given window are excluded from that window.
1Y
67%
of 459 industry peers · 53.7% return
3Y
24%
of 405 industry peers · -82.4% return
5Y
insufficient peer history
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Median price return by industry across the Health Care sector, ranked by 5Y. Biotechnology is ACRV's own industry. Use this to see which corners of the sector have carried the returns.
Industry Names 1Y med3Y med5Y med Top 3 by 5Y
Health Care Distributors 7 11.3%87.6%129.3% CAH 398% · MCK 348% · COR 178%
Managed Health Care 8 29.5%-0.6%2.9% OSCR 95% · HQY 50% · ELV 13%
Health Care Services 20 19.7%40.8%1.0% HIMS 266% · RDNT 138% · DGX 75%
Health Care Facilities 24 6.2%-4.5%-18.3% THC 254% · NHC 246% · ENSG 114%
Health Care Equipment 51 -3.6%-6.4%-20.1% POCI 10900% · UFPT 329% · GKOS 202%
Health Care Supplies 12 32.6%-15.8%-36.7% LNTH 282% · HAE 66% · MMSI 26%
Pharmaceuticals 63 -3.1%8.0%-38.3% LQDA 2435% · INDV 1218% · ETON 1034%
Life Sciences Tools & Services 108 1.5%-32.7%-70.0% SNWV 1808% · MEDP 229% · AXGN 202%
Health Care Technology 21 -25.9%-57.7%-75.1% SPOK 79% · HSTM -2% · VEEV -17%
Biotechnology ← 365 10.0%-25.2%-79.0% BRTX 99450% · DNTH 1554% · CELZ 1529%
Median of constituents with a full price history over each window. Top names are unfiltered by size in this render.

Latest Trefis Analyses

TitleDate
0DASHBOARDS 
1Acrivon Therapeutics Earnings Notes12/16/2025
Title
0ARTICLES

Recent Active Movers

Peer Comparisons

Peers to compare with:

Financials

ACRVZNTLAPREIDYATNGXORICMedian
NameAcrivon .Zentalis.Aprea Th.IDEAYA B.Tango Th.ORIC Pha. 
Mkt Price2.063.800.8440.1123.3413.248.52
Mkt Cap0.10.30.03.73.51.40.9
Rev LTM0002345400
Op Inc LTM-78-153-13-217-136-156-145
FCF LTM-64-128-12-114-144-112-113
FCF 3Y Avg-64-149-13-182-138-111-125
CFO LTM-63-128-12-112-144-112-112
CFO 3Y Avg-62-149-13-179-137-111-124

Growth & Margins

ACRVZNTLAPREIDYATNGXORICMedian
NameAcrivon .Zentalis.Aprea Th.IDEAYA B.Tango Th.ORIC Pha. 
Rev Chg LTM--100.0%-3,244.7%121.5%-121.5%
Rev Chg 3Y Avg---1,043.2%34.9%-539.1%
Rev Chg Q-----100.0%--100.0%
QoQ Delta Rev Chg LTM---3.9%-5.6%--0.8%
Op Inc Chg LTM17.0%10.5%10.6%43.5%13.3%-4.3%12.0%
Op Inc Chg 3Y Avg-20.4%12.2%4.2%-61.0%-7.2%-19.3%-13.2%
Op Mgn LTM----92.7%-253.4%--173.0%
Op Mgn 3Y Avg----2,393.9%-404.1%--1,399.0%
QoQ Delta Op Mgn LTM----11.2%-47.2%--29.2%
CFO/Rev LTM----47.7%-267.4%--157.6%
CFO/Rev 3Y Avg----1,778.5%-386.7%--1,082.6%
FCF/Rev LTM----48.6%-268.1%--158.4%
FCF/Rev 3Y Avg----1,806.2%-388.8%--1,097.5%

Valuation

ACRVZNTLAPREIDYATNGXORICMedian
NameAcrivon .Zentalis.Aprea Th.IDEAYA B.Tango Th.ORIC Pha. 
Mkt Cap0.10.30.03.73.51.40.9
P/S---15.865.0-40.4
P/Op Inc-1.1-1.8-3.4-17.0-25.7-9.2-6.3
P/EBIT-1.1-1.8-3.4-17.0-25.7-9.2-6.3
P/E-1.2-1.9-3.7-21.1-28.3-10.2-6.9
P/CFO-1.4-2.1-3.7-33.1-24.3-12.8-8.3
Total Yield-86.1%-51.5%-27.4%-4.7%-3.5%-9.8%-18.6%
Dividend Yield0.0%0.0%0.0%0.0%0.0%0.0%0.0%
FCF Yield 3Y Avg-90.8%-91.8%-69.5%-8.1%-14.1%-15.0%-42.3%
D/E0.00.10.00.00.00.00.0
Net D/E-1.0-0.5-0.9-0.2-0.3-0.2-0.4

Returns

ACRVZNTLAPREIDYATNGXORICMedian
NameAcrivon .Zentalis.Aprea Th.IDEAYA B.Tango Th.ORIC Pha. 
1M Rtn37.3%-19.8%35.3%13.0%-14.1%19.6%16.3%
3M Rtn28.7%-5.0%-6.0%36.1%6.2%56.7%17.5%
6M Rtn36.4%59.0%-8.5%24.6%109.5%-1.6%30.5%
12M Rtn53.7%124.9%-46.4%63.4%247.8%29.4%58.6%
3Y Rtn-82.4%-85.7%-77.3%36.6%259.6%47.8%-20.4%
1M Excs Rtn31.8%-26.4%28.4%6.5%-19.0%10.1%8.3%
3M Excs Rtn27.0%-6.7%-7.8%34.4%4.4%54.9%15.7%
6M Excs Rtn24.3%46.9%-20.6%12.5%97.4%-13.7%18.4%
12M Excs Rtn32.5%89.8%-66.6%41.5%219.3%10.1%37.0%
3Y Excs Rtn-155.9%-159.1%-150.9%-31.2%142.4%-26.6%-91.0%

Comparison Analyses

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Financials

Segment Financials

Net Income by Segment
$ Mil202520242023
Research and development of precision oncology therapies-78-81-60
Total-78-81-60


Assets by Segment
$ Mil202320222021
Research and development of precision oncology therapies138181107
Total138181107


Price Behavior

Price Behavior
Market Price$2.06 
Market Cap ($ Bil)0.1 
First Trading Date11/15/2022 
Distance from 52W High-31.6% 
   50 Days200 Days
DMA Price$1.80$1.87
DMA Trendindeterminateup
Distance from DMA14.6%10.4%
 3M1YR
Volatility73.3%95.8%
Downside Capture52.96195.86
Upside Capture168.53204.93
Correlation (SPY)33.5%26.5%
ACRV Betas & Captures as of 7/31/2026

 1M2M3M6M1Y3Y
Beta1.751.701.762.041.971.70
Up Beta5.744.303.533.252.061.79
Down Beta2.552.091.791.291.631.73
Up Capture-93%60%57%165%311%114%
Bmk +ve Days11223567138427
Stock +ve Days8202656113335
Down Capture163%97%170%182%157%112%
Bmk -ve Days11212859114326
Stock -ve Days13213465125388

[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with ACRV
ACRV51.7%95.2%0.86-
Sector ETF (XLV)26.7%16.0%1.2916.8%
Equity (SPY)20.1%12.8%1.1626.4%
Gold (GLD)30.9%29.0%0.9211.6%
Commodities (DBC)39.9%20.3%1.54-7.2%
Real Estate (VNQ)9.9%13.7%0.448.4%
Bitcoin (BTCUSD)-30.1%43.7%-0.7021.0%

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Based On 5-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with ACRV
ACRV-33.8%102.4%-0.06-
Sector ETF (XLV)6.3%15.1%0.2317.4%
Equity (SPY)13.1%17.2%0.5923.0%
Gold (GLD)19.7%18.7%0.858.3%
Commodities (DBC)11.5%19.6%0.462.0%
Real Estate (VNQ)2.0%18.9%0.0015.9%
Bitcoin (BTCUSD)9.6%52.7%0.3711.2%

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Based On 10-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with ACRV
ACRV-18.6%102.4%-0.06-
Sector ETF (XLV)10.5%16.7%0.5117.4%
Equity (SPY)15.2%17.9%0.7223.0%
Gold (GLD)12.2%16.3%0.618.3%
Commodities (DBC)7.3%18.0%0.332.0%
Real Estate (VNQ)5.0%20.7%0.2015.9%
Bitcoin (BTCUSD)63.4%66.1%1.0311.2%

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Short Interest

Short Interest: As Of Date8142026
Short Interest: Shares Quantity1.2 Mil
Short Interest: % Change Since 7312026-8.8%
Average Daily Volume0.3 Mil
Days-to-Cover Short Interest4.0 days
Basic Shares Quantity41.8 Mil
Short % of Basic Shares3.0%

Earnings Returns History

Updated 8/21/2026
Expand for More
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
8/12/20267.6%39.0% 
5/13/20260.0%-8.3%-22.9%
3/19/20263.7%-7.3%8.5%
1/8/2026-34.6%-38.0%-43.4%
11/13/20258.2%9.2%16.9%
8/13/20256.1%-0.8%16.0%
5/14/2025-3.5%0.9%5.3%
3/25/2025-51.6%-68.8%-63.1%
...
SUMMARY STATS   
# Positive976
# Negative799
Median Positive6.8%9.2%16.5%
Median Negative-5.5%-8.3%-16.3%
Max Positive10.6%39.0%30.9%
Max Negative-51.6%-68.8%-63.1%
Collapse to Preview
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
8/12/20267.6%39.0% 
5/13/20260.0%-8.3%-22.9%
3/19/20263.7%-7.3%8.5%
1/8/2026-34.6%-38.0%-43.4%
11/13/20258.2%9.2%16.9%
8/13/20256.1%-0.8%16.0%
5/14/2025-3.5%0.9%5.3%
3/25/2025-51.6%-68.8%-63.1%
11/13/2024-5.5%-24.0%-16.3%
8/13/2024-4.5%9.7%25.2%
5/14/2024-1.4%0.8%-11.0%
3/28/202410.6%3.5%30.9%
11/9/2023-19.2%-8.6%-11.4%
8/11/20236.8%-4.8%-0.1%
5/9/20236.8%10.9%-1.9%
3/13/20235.1%-0.2%-50.4%
SUMMARY STATS   
# Positive976
# Negative799
Median Positive6.8%9.2%16.5%
Median Negative-5.5%-8.3%-16.3%
Max Positive10.6%39.0%30.9%
Max Negative-51.6%-68.8%-63.1%

SEC Filings

Expand for More
Report DateFiling DateFiling
06/30/202608/12/202610-Q
03/31/202605/13/202610-Q
12/31/202503/19/202610-K
09/30/202511/13/202510-Q
06/30/202508/13/202510-Q
03/31/202505/14/202510-Q
12/31/202403/27/202510-K
09/30/202411/13/202410-Q
06/30/202408/13/202410-Q
03/31/202405/14/202410-Q
12/31/202303/28/202410-K
09/30/202311/09/202310-Q
06/30/202308/11/202310-Q
03/31/202305/09/202310-Q
12/31/202203/28/202310-K
09/30/202212/15/202210-Q
Collapse to Preview
Report DateFiling DateFiling
06/30/202608/12/202610-Q
03/31/202605/13/202610-Q
12/31/202503/19/202610-K
09/30/202511/13/202510-Q
06/30/202508/13/202510-Q
03/31/202505/14/202510-Q
12/31/202403/27/202510-K
09/30/202411/13/202410-Q
06/30/202408/13/202410-Q
03/31/202405/14/202410-Q
12/31/202303/28/202410-K
09/30/202311/09/202310-Q
06/30/202308/11/202310-Q
03/31/202305/09/202310-Q
12/31/202203/28/202310-K
09/30/202212/15/202210-Q
06/30/202211/16/2022424B4

Recent Forward Guidance

Updated 8/13/2026

Latest: Q2 2026 Earnings Reported 8/12/2026

Forward GuidanceGuidance Change
MetricLowMidHigh% Chg% DeltaChangePrior
2027 Cash Runway 4 33.3% RaisedGuidance: 3 for 2027

Prior: Q1 2026 Earnings Reported 5/13/2026

Forward GuidanceGuidance Change
MetricLowMidHigh% Chg% DeltaChangePrior
Q3 2027 Cash Runway 3   RaisedGuidance: 2 for Q2 2027

Insider Activity

Updated 8/27/2026
Expand for More
#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Blume-Jensen, PeterPresident and CEODirectSell82720262.2114,03630,9694,920,387Form
2Peterson, KatharineChief Accounting OfficerDirectSell82020262.0110120336,246Form
3Miller, MaryChief Legal OfficerDirectSell82020262.01185372164,838Form
4Gamelin, ErickChief Development OfficerDirectSell82020262.01400804105,710Form
5Devroe, EricChief Operating OfficerDirectSell82020262.016041,214294,161Form
Collapse to Preview
#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Blume-Jensen, PeterPresident and CEODirectSell82720262.2114,03630,9694,920,387Form
2Peterson, KatharineChief Accounting OfficerDirectSell82020262.0110120336,246Form
3Miller, MaryChief Legal OfficerDirectSell82020262.01185372164,838Form
4Gamelin, ErickChief Development OfficerDirectSell82020262.01400804105,710Form
5Devroe, EricChief Operating OfficerDirectSell82020262.016041,214294,161Form
6Blume-Jensen, PeterPresident and CEODirectSell82020262.011,2292,4704,510,617Form
7Blume-Jensen, PeterPresident and CEOSee FootnoteSell82020262.01484973775,577Form
8Levy, Adam DChief Financial OfficerDirectSell80620261.571,1421,793103,633Form
9Miller, MaryChief Legal OfficerDirectSell72320261.765731,008144,661Form
10Blume-Jensen, PeterPresident and CEODirectBuy11620261.6849,00082,1243,512,512Form
11Levy, Adam DChief Financial OfficerDirectBuy11620261.708,83214,99935,635Form
12Devroe, EricChief Operating OfficerDirectBuy11520261.7210,00017,218129,665Form
Core Cache Last Updated: 8/30/2026