Tearsheet

Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.

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Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -26%

Strong revenue growth
Rev Chg LTMRevenue Change % Last Twelve Months (LTM) is 3118%

Low stock price volatility
Vol 12M is 46%

Megatrend and thematic drivers
Megatrends include Precision Medicine, and Aging Population & Chronic Disease. Themes include Targeted Therapies, Oncology Treatments, Show more.

Weak multi-year price returns
2Y Excs Rtn is -69%, 3Y Excs Rtn is -54%

Meaningful short interest
Short Interest Days-to-CoverDTC = (Short Interest Share Quantity) / (Average Daily Trading Volume). Reflects how many days it would take to cover (close out) the short interest based on average volumes. High DTC can signify an increased risk of a short squeeze. is 13.96, Short Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 13%

Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -183 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -81%

Significant share based compensation
SBC/Rev LTMShare Based Compensation / Revenue (Sales), Last Twelve Months (LTM) is 22%

Not cash flow generative
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -38%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -39%

Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -10.0%

Key risks
IDYA key risks include [1] the uncertain clinical and regulatory success of its precision oncology pipeline and [2] its ongoing unprofitability and need for future funding.

0 Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -26%
1 Strong revenue growth
Rev Chg LTMRevenue Change % Last Twelve Months (LTM) is 3118%
2 Low stock price volatility
Vol 12M is 46%
3 Megatrend and thematic drivers
Megatrends include Precision Medicine, and Aging Population & Chronic Disease. Themes include Targeted Therapies, Oncology Treatments, Show more.
4 Weak multi-year price returns
2Y Excs Rtn is -69%, 3Y Excs Rtn is -54%
5 Meaningful short interest
Short Interest Days-to-CoverDTC = (Short Interest Share Quantity) / (Average Daily Trading Volume). Reflects how many days it would take to cover (close out) the short interest based on average volumes. High DTC can signify an increased risk of a short squeeze. is 13.96, Short Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 13%
6 Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -183 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -81%
7 Significant share based compensation
SBC/Rev LTMShare Based Compensation / Revenue (Sales), Last Twelve Months (LTM) is 22%
8 Not cash flow generative
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -38%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -39%
9 Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -10.0%
10 Key risks
IDYA key risks include [1] the uncertain clinical and regulatory success of its precision oncology pipeline and [2] its ongoing unprofitability and need for future funding.

Valuation, Metrics & Events

Price Chart

Why The Stock Moved

Qualitative Assessment

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Updated on 6/1/2026
IDEAYA Biosciences (IDYA) stock has lost about 15% since 2/28/2026 because of the following key factors:

1. Widening Net Loss and Declining Collaboration Revenue. IDEAYA Biosciences reported a net loss of $98.5 million for the first quarter of 2026, a significant increase from the $83.3 million net loss in the prior quarter. Concurrently, collaboration revenue declined to $6.6 million in Q1 2026, down from $10.9 million in Q4 2025. This indicated an increasing cash burn and reduced immediate income, contributing to investor concern.

2. Significant Downgrades in Future Revenue and Earnings Per Share (EPS) Estimates by Analysts. Following the Q1 2026 results, analysts drastically cut their 2026 revenue forecasts for IDEAYA Biosciences from an initial consensus of approximately $37 million to about $27 million, representing an 88% projected decline in sales compared to the trailing twelve months. Alongside this, expected per-share losses were increased to $4.29 for 2026, up from previous estimates of $4.03 per share. These revisions to the company's financial outlook signaled increased challenges for profitability and negatively impacted stock sentiment.

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Stock Movement Drivers

Fundamental Drivers

The -13.4% change in IDYA stock from 2/28/2026 to 6/2/2026 was primarily driven by a -15.9% change in the company's P/S Multiple.
(LTM values as of)22820266022026Change
Stock Price ($)32.2027.87-13.4%
Change Contribution By: 
Total Revenues ($ Mil)2192253.0%
P/S Multiple13.011.0-15.9%
Shares Outstanding (Mil)8989-0.1%
Cumulative Contribution-13.4%

LTM = Last Twelve Months as of date shown

Market Drivers

2/28/2026 to 6/2/2026
ReturnCorrelation
IDYA-13.4% 
Market (SPY)11.0%40.1%
Sector (XLV)-8.2%48.7%

Fundamental Drivers

The -21.8% change in IDYA stock from 11/30/2025 to 6/2/2026 was primarily driven by a -25.2% change in the company's P/S Multiple.
(LTM values as of)113020256022026Change
Stock Price ($)35.6227.87-21.8%
Change Contribution By: 
Total Revenues ($ Mil)2152254.9%
P/S Multiple14.711.0-25.2%
Shares Outstanding (Mil)8989-0.2%
Cumulative Contribution-21.8%

LTM = Last Twelve Months as of date shown

Market Drivers

11/30/2025 to 6/2/2026
ReturnCorrelation
IDYA-21.8% 
Market (SPY)11.8%28.9%
Sector (XLV)-6.4%34.1%

Fundamental Drivers

The 40.1% change in IDYA stock from 5/31/2025 to 6/2/2026 was primarily driven by a 3118.1% change in the company's Total Revenues ($ Mil).
(LTM values as of)53120256022026Change
Stock Price ($)19.8927.8740.1%
Change Contribution By: 
Total Revenues ($ Mil)72253118.1%
P/S Multiple251.111.0-95.6%
Shares Outstanding (Mil)8889-0.4%
Cumulative Contribution40.1%

LTM = Last Twelve Months as of date shown

Market Drivers

5/31/2025 to 6/2/2026
ReturnCorrelation
IDYA40.1% 
Market (SPY)30.4%32.3%
Sector (XLV)12.3%37.0%

Fundamental Drivers

The 22.0% change in IDYA stock from 5/31/2023 to 6/2/2026 was primarily driven by a 374.7% change in the company's Total Revenues ($ Mil).
(LTM values as of)53120236022026Change
Stock Price ($)22.8427.8722.0%
Change Contribution By: 
Total Revenues ($ Mil)47225374.7%
P/S Multiple23.311.0-52.9%
Shares Outstanding (Mil)4889-45.5%
Cumulative Contribution22.0%

LTM = Last Twelve Months as of date shown

Market Drivers

5/31/2023 to 6/2/2026
ReturnCorrelation
IDYA22.0% 
Market (SPY)88.9%35.8%
Sector (XLV)20.4%36.8%

Return vs. Risk

Price Returns Compared

 202120222023202420252026Total [1]
Returns
IDYA Return69%-23%96%-28%35%-16%107%
Peers Return-22%-48%11%-55%54%81%-43%
S&P 500 Return27%-19%24%23%16%11%102%

Monthly Win Rates [3]
IDYA Win Rate67%58%67%25%58%50% 
Peers Win Rate42%33%45%40%55%57% 
S&P 500 Win Rate75%42%67%75%67%67% 

Max Drawdowns [4]
IDYA Max Drawdown-30%-66%-29%-47%-44%-26% 
Peers Max Drawdown-58%-66%-65%-73%-58%-34% 
S&P 500 Max Drawdown-5%-25%-10%-8%-19%-9% 


[1] Cumulative total returns since the beginning of 2021
[2] Peers: ZNTL, TNGX, KURA, RLAY, BDTX.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 6/2/2026 (YTD)

How Low Can It Go

EventIDYAS&P 500
2025 US Tariff Shock
  % Loss-29.8%-18.8%
  % Gain to Breakeven42.5%23.1%
  Time to Breakeven24 days79 days
2023 SVB Regional Banking Crisis
  % Loss-25.3%-6.7%
  % Gain to Breakeven33.9%7.1%
  Time to Breakeven12 days31 days
2022 Inflation Shock & Fed Tightening
  % Loss-65.5%-24.5%
  % Gain to Breakeven190.1%32.4%
  Time to Breakeven389 days427 days
2020 COVID-19 Crash
  % Loss-55.6%-33.7%
  % Gain to Breakeven125.1%50.9%
  Time to Breakeven52 days140 days

Compare to ZNTL, TNGX, KURA, RLAY, BDTX

In The Past

IDEAYA Biosciences's stock fell -29.8% during the 2025 US Tariff Shock. Such a loss loss requires a 42.5% gain to breakeven.

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EventIDYAS&P 500
2025 US Tariff Shock
  % Loss-29.8%-18.8%
  % Gain to Breakeven42.5%23.1%
  Time to Breakeven24 days79 days
2023 SVB Regional Banking Crisis
  % Loss-25.3%-6.7%
  % Gain to Breakeven33.9%7.1%
  Time to Breakeven12 days31 days
2022 Inflation Shock & Fed Tightening
  % Loss-65.5%-24.5%
  % Gain to Breakeven190.1%32.4%
  Time to Breakeven389 days427 days
2020 COVID-19 Crash
  % Loss-55.6%-33.7%
  % Gain to Breakeven125.1%50.9%
  Time to Breakeven52 days140 days

Compare to ZNTL, TNGX, KURA, RLAY, BDTX

In The Past

IDEAYA Biosciences's stock fell -29.8% during the 2025 US Tariff Shock. Such a loss loss requires a 42.5% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

About IDEAYA Biosciences (IDYA)

IDEAYA Biosciences, Inc., a synthetic lethality-focused precision medicine oncology company, focuses on the discovery and development of targeted therapeutics for patient populations selected using molecular diagnostics. The company's lead product candidates include IDE397, a methionine adenosyltransferase 2a inhibitor that is in Phase I clinical trial for patients with solid tumors having methylthioadenosine phosphorylase deletions; and IDE196, a protein kinase C inhibitor that is in Phase I/II clinical trial for genetically defined cancers having GNAQ or GNA11 gene mutations. Its preclinical pipeline includes various synthetic lethality programs targeting PARG inhibitor in tumors for patients having tumors with a defined biomarker based on genetic mutations and/or molecular signatures; Pol Theta inhibitors in tumors with BRCA or other homologous recombination deficiency mutations; and WRN inhibitors in tumors with high microsatellite instability. The company has a research collaboration agreement with Cancer Research UK and the University of Manchester to develop small molecule inhibitors of Poly (ADP-ribose) glycohydrolase; and a clinical trial collaboration and supply agreement with Pfizer Inc. for Phase I/II study in metastatic uveal melanoma, skin melanoma, and other solid tumors, as well as a strategic partnership with GlaxoSmithKline plc. IDEAYA Biosciences, Inc. was incorporated in 2015 and is headquartered in South San Francisco, California.

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Here are 1-2 brief analogies for IDEAYA Biosciences (IDYA):

  • Like Moderna or BioNTech, but focused on developing highly targeted cancer therapies instead of vaccines.
  • A smaller, early-stage Amgen or Gilead Sciences, singularly dedicated to discovering groundbreaking precision oncology drugs.

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  • IDE397: A methionine adenosyltransferase 2a inhibitor currently in Phase I clinical trial for solid tumors with MTAP deletions.
  • IDE196: A protein kinase C inhibitor in Phase I/II clinical trial for genetically defined cancers having GNAQ or GNA11 gene mutations.
  • PARG inhibitor program: A preclinical program developing small molecule inhibitors for tumors with a defined biomarker based on genetic mutations and/or molecular signatures.
  • Pol Theta inhibitor program: A preclinical program developing inhibitors for tumors with BRCA or other homologous recombination deficiency mutations.
  • WRN inhibitor program: A preclinical program developing inhibitors for tumors with high microsatellite instability.

AI Analysis | Feedback

IDEAYA Biosciences (IDYA) is a clinical-stage precision medicine oncology company focused on the discovery and development of targeted therapeutics. As such, it does not currently sell commercial products directly to individuals or traditional customers in the way a retail or service company would. Instead, IDEAYA Biosciences generates revenue and advances its pipeline through strategic partnerships and collaborations with larger pharmaceutical companies and research institutions. These partners contribute funding, expertise, and resources, making them the primary financial stakeholders and collaborators in IDEAYA's business model. Based on the provided information, IDEAYA Biosciences' major "customers" or strategic partners (who provide funding and support for product development) are:
  • Pfizer Inc. (NYSE: PFE)
  • GlaxoSmithKline plc (NYSE: GSK)

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Yujiro S. Hata, President, Chief Executive Officer, Founder, and Director

Mr. Hata founded IDEAYA Biosciences in June 2015 as its first employee, CEO, and Director, and led the company's IPO on NASDAQ in May 2019. From 2015 to 2018, he served as an Executive-in-Residence at 5AM Ventures. Prior to IDEAYA, he was Chief Operating Officer at Flexus Biosciences from 2014 to August 2015, guiding it through its acquisition by Bristol-Myers Squibb in April 2015. He also served as Chief Operating Officer at FLX Bio (later RAPT Therapeutics), a spinout of Flexus Biosciences. From 2010 to 2014, he was Vice President, Corporate Development and Strategy at Onyx Pharmaceuticals, including through its acquisition by Amgen. From 2002 to 2010, Mr. Hata held roles including Chief Business Officer at Enanta Pharmaceuticals, where he established a partnership with Abbott Labs that led to the discovery of protease inhibitors in HCV therapies. His background includes earlier roles at McKinsey, ImClone, and Columbia Medical School. His association with 5AM Ventures and leading Flexus Biosciences through an acquisition indicates a pattern of involvement with and successful exits from privately backed and startup companies.

Joshua Bleharski, Ph.D., Chief Financial Officer

Dr. Bleharski was appointed Chief Financial Officer in February 2025. He joined IDEAYA from J.P. Morgan, where he spent nearly 17 years as Managing Director and Global Co-Head of Biopharma in the Healthcare Investment Banking group. In this role, he advised biotechnology companies on financing and strategic transactions valued at over $65 billion. His prior experience includes serving as a Senior Staff Scientist at a private biotechnology company and completing post-doctoral fellowships at LIAI and UCLA School of Medicine. He holds a Ph.D. in Immunology from UCLA and an MBA from UC Berkeley's Haas School of Business.

Michael White, Ph.D., Senior Vice President, Chief Scientific Officer, Head of Research

Dr. White serves as the Chief Scientific Officer and Head of Research for IDEAYA Biosciences.

Darrin M. Beaupre, M.D., Ph.D., Chief Medical Officer

Dr. Beaupre is the Chief Medical Officer at IDEAYA Biosciences. He previously served as an Assistant Professor in the Department of Interdisciplinary Oncology at the Moffit Cancer Center. His distinctions include receiving a Clinical Scholars in Oncology Award from the National Cancer Institute. Dr. Beaupre completed his Medical Oncology and Hematology Fellowship and post-doctoral research training at the University of Miami Sylvester Cancer Center.

Theodora (Theo) Ross, M.D., Ph.D., Chief Development Officer

Dr. Ross was appointed Chief Development Officer in February 2026. In this role, she is responsible for leading early clinical development for IDEAYA's oncology pipeline and guiding the company's long-term R&D strategy. Prior to joining IDEAYA, Dr. Ross was Vice President, Head of Early Oncology R&D and Site Head for the Bay Area at AbbVie.

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Key Risks to IDEAYA Biosciences (IDYA)

  1. Clinical Trial Failure and Regulatory Approval Risk: IDEAYA Biosciences' primary assets are currently in early-stage clinical trials (Phase I and Phase I/II) or preclinical development. The success of these candidates, such as IDE397 and IDE196, is uncertain. Many drug candidates fail during clinical development due to lack of efficacy, unacceptable safety profiles, or other issues. Even if trials are successful, there is no guarantee that regulatory bodies (like the FDA) will approve the drugs for commercialization. Failure at any stage of development or inability to secure regulatory approval would severely impact the company's prospects and valuation.
  2. Intellectual Property Protection Risk: As a precision medicine oncology company, IDEAYA Biosciences relies heavily on its ability to discover, develop, and protect proprietary compounds and technologies. The company's competitive advantage and future revenue potential depend on obtaining and maintaining patent protection for its product candidates and related intellectual property. If the company is unable to secure strong patent protection, or if its patents are challenged, invalidated, or circumvented by competitors, it could significantly diminish the value of its pipeline and expose it to competition.
  3. Intense Competition in the Oncology Market: The field of oncology drug development is highly competitive, with numerous large pharmaceutical companies and biotechnology firms developing similar or alternative therapies. IDEAYA's product candidates, if approved, would compete with existing treatments and new therapies that are continually being developed by others. The ability to successfully commercialize its products will depend on their efficacy, safety, market acceptance, and competitive pricing, all within a rapidly evolving and competitive landscape.

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IDEAYA Biosciences (NASDAQ: IDYA) focuses on precision medicine oncology. The addressable markets for its main product candidates are as follows:

  • IDE397 (Methionine Adenosyltransferase 2a Inhibitor): This product targets solid tumors with methylthioadenosine phosphorylase (MTAP) deletions. MTAP deletion is found in approximately 15% of solid tumors globally. The global solid tumor market is projected to reach USD 283.8 billion by 2029. Therefore, the estimated global addressable market for IDE397 is approximately USD 42.6 billion. Additionally, the annual incidence of MTAP-deletion solid tumors across priority types such as non-small cell lung cancer, bladder, gastric, and esophageal cancers is estimated to be greater than 50,000 patients in the U.S., EU5 (Germany, France, Italy, Spain, and the UK), and Japan.
  • IDE196 (Protein Kinase C Inhibitor): This product is in development for genetically defined cancers having GNAQ or GNA11 gene mutations, primarily metastatic uveal melanoma. GNAQ and GNA11 gene mutations are present in approximately 80% to 90% of uveal melanoma cases. The global uveal melanoma treatment market was valued at USD 1.2 billion in 2024 and is projected to reach USD 2.5 billion by 2035. This market size is global.

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IDEAYA Biosciences (NASDAQ: IDYA) is a precision medicine oncology company with a pipeline focused on synthetic lethality. While analysts have recently adjusted down revenue estimates for 2026, forecasts for 2027 and 2028 indicate a potential increase, driven by the advancement and eventual commercialization of its therapeutic candidates and milestone achievements from strategic collaborations.

Here are 3-5 expected drivers of future revenue growth for IDEAYA Biosciences over the next 2-3 years:

  1. Commercialization of Darovasertib (IDE196) for Uveal Melanoma: Darovasertib, a protein kinase C inhibitor, is IDEAYA's lead product candidate, currently in Phase 2/3 registrational trials for metastatic uveal melanoma (mUM). Topline results for the OptimUM-02 trial, evaluating darovasertib in combination with crizotinib, are anticipated by approximately the last week of March 2026. Furthermore, darovasertib is expected to be in three randomized Phase 3 registrational trials for uveal melanoma (metastatic, neoadjuvant, and adjuvant settings) by the first half of 2026. The company has also received U.S. FDA Breakthrough Therapy Designation for darovasertib in neoadjuvant uveal melanoma. IDEAYA has partnered with Servier for exclusive rights to darovasertib outside the United States, a collaboration that includes an upfront payment, potential milestone payments of up to $320 million, and double-digit royalties on ex-U.S. net sales, while IDEAYA retains all U.S. commercial rights. Commercial readiness activities are ongoing in anticipation of these critical trial results and potential market entry.
  2. Achievement of Development and Commercial Milestone Payments from Strategic Collaborations: IDEAYA has established partnerships with major pharmaceutical companies, which serve as a significant source of current and future revenue through milestone payments. Notable collaborations include the agreement with Servier for darovasertib (outside U.S. rights), and GlaxoSmithKline (GSK) for the Werner Helicase inhibitor program and the Pol Theta program. For the Werner Helicase inhibitor, IDEAYA is eligible for up to $465 million in development and regulatory milestones, $475 million in commercial milestones, and 50% of U.S. net profits, along with tiered royalties on global non-U.S. net sales. A $7 million milestone was earned from GSK upon IND clearance of IDE275 (Werner Helicase) in October 2024. The Pol Theta Helicase program also has a potential $10 million milestone payment from GSK upon Phase 2 expansion. Additional collaborations, such as with Gilead for the IDE397 combination and Biocytogen for the B7H3/PTK7 Topo-Payload BsADC program, offer further potential milestone payments as these programs advance through development.
  3. Advancement and Potential Market Entry of IDE849 (DLL3 TOP1 ADC): IDEAYA is progressing IDE849, a DLL3 TOP1 ADC, with the initiation of a monotherapy registrational study in the second line/refractory setting of small cell lung cancer (SCLC) and/or neuroendocrine carcinomas (NEC) targeted by the end of 2026. Preliminary clinical data updates from the IDEAYA-sponsored global Phase 1 trial of IDE849 are also expected by the end of 2026. The successful progression and potential commercialization of IDE849 represent another distinct avenue for product-based revenue growth within the next 2-3 years.
  4. Progression of Other Clinical and Preclinical Synthetic Lethality Pipeline Programs: Beyond darovasertib and IDE849, IDEAYA has a robust pipeline of synthetic lethality programs that are expected to contribute to future revenue growth through continued milestone payments and eventual product launches. These include IDE397 (MAT2A inhibitor), which has ongoing Phase 1/2 combination trials with updated data expected in 2026; PARG inhibitors (IDE161); Pol Theta inhibitors (IDE705/GSK101); and Werner Helicase inhibitors (IDE275/GSK959). The company is also targeting new IND filings for IDE892 (PRMT5), IDE034 (B7H3/PTK7 ADC), and IDE574 (KAT6/7) in 2025/2026, indicating a continuous stream of potential future therapeutic candidates.

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Share Issuance

  • IDEAYA Biosciences granted non-qualified stock options to purchase an aggregate of 346,200 shares to three newly hired employees on February 26, 2026, with an exercise price of $31.90.
  • On January 29, 2026, the company granted non-qualified stock options to purchase an aggregate of 44,200 shares to a newly hired employee, with an exercise price of $32.99.

Inbound Investments

  • IDEAYA Biosciences reported approximately $1.1 billion in cash, cash equivalents, and marketable securities as of September 30, 2025, which is projected to fund operations into 2030.
  • The company received a $210.0 million upfront payment from Servier in 2025 related to an exclusive license agreement for darovasertib.
  • IDEAYA has strategic partnerships, including one with GlaxoSmithKline (GSK) that could yield up to approximately $3 billion in aggregate cash milestones across its MAT2A, Pol Theta, and Werner Helicase programs.

Capital Expenditures

  • Capital expenditures for IDEAYA Biosciences were $2.64 million in 2021, $3.44 million in 2022, and $2.37 million in 2023.
  • In 2024, capital expenditures were $3.86 million, and in 2025, they were $2.37 million.

Better Bets vs. IDEAYA Biosciences (IDYA)

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Peer Comparisons

Peers to compare with:

Financials

IDYAZNTLTNGXKURARLAYBDTXMedian
NameIDEAYA B.Zentalis.Tango Th.Kura Onc.Relay Th.Black Di. 
Mkt Price27.873.9521.508.9715.702.1812.34
Mkt Cap2.50.33.10.82.80.11.6
Rev LTM2250577211034
Op Inc LTM-183-145-118-318-296-46-164
FCF LTM-88-126-143-84-213-34-107
FCF 3Y Avg-164-163-134-37-258-30-148
CFO LTM-86-126-142-78-213-34-106
CFO 3Y Avg-160-163-133-35-256-30-147

Growth & Margins

IDYAZNTLTNGXKURARLAYBDTXMedian
NameIDEAYA B.Zentalis.Tango Th.Kura Onc.Relay Th.Black Di. 
Rev Chg LTM3,118.1%-100.0%39.0%5.4%39.0%-100.0%22.2%
Rev Chg 3Y Avg998.7%-33.0%-944.8%-944.8%
Rev Chg Q---100.0%29.5%-60.9%-100.0%-80.5%
QoQ Delta Rev Chg LTM3.0%--8.6%6.2%-30.5%-100.0%-8.6%
Op Inc Chg LTM49.1%27.7%19.4%-56.2%21.6%-1,046.5%20.5%
Op Inc Chg 3Y Avg-63.6%14.2%-1.7%-31.6%4.1%-315.7%-16.6%
Op Mgn LTM-81.4%--206.2%-443.5%-2,776.6%--324.9%
Op Mgn 3Y Avg-2,085.3%--300.3%--2,916.5%--2,085.3%
QoQ Delta Op Mgn LTM-8.6%--27.8%6.4%-805.1%--18.2%
CFO/Rev LTM-38.1%--248.4%-108.9%-1,998.3%--178.6%
CFO/Rev 3Y Avg-1,552.5%--301.1%--2,114.3%--1,552.5%
FCF/Rev LTM-39.0%--250.1%-117.9%-1,998.5%--184.0%
FCF/Rev 3Y Avg-1,579.0%--303.2%--2,120.8%--1,579.0%

Valuation

IDYAZNTLTNGXKURARLAYBDTXMedian
NameIDEAYA B.Zentalis.Tango Th.Kura Onc.Relay Th.Black Di. 
Mkt Cap2.50.33.10.82.80.11.6
P/S11.0-54.211.1264.5-32.6
P/Op Inc-13.5-1.9-26.3-2.5-9.5-2.7-6.1
P/EBIT-13.5-1.9-26.3-2.7-9.5-2.7-6.1
P/E-17.7-2.2-28.8-2.7-10.4-2.9-6.6
P/CFO-28.8-2.2-21.8-10.2-13.2-3.7-11.7
Total Yield-5.7%-44.7%-3.5%-37.1%-9.7%-34.6%-22.1%
Dividend Yield0.0%0.0%0.0%0.0%0.0%0.0%0.0%
FCF Yield 3Y Avg-8.5%-76.1%-36.3%-0.1%-33.3%-13.2%-23.3%
D/E0.00.10.00.00.00.10.0
Net D/E-0.3-0.6-0.1-0.7-0.2-0.8-0.4

Returns

IDYAZNTLTNGXKURARLAYBDTXMedian
NameIDEAYA B.Zentalis.Tango Th.Kura Onc.Relay Th.Black Di. 
1M Rtn-1.1%-3.4%2.5%2.3%23.4%-16.2%0.6%
3M Rtn-18.8%66.0%87.0%5.5%59.4%-5.2%32.5%
6M Rtn-17.3%194.8%113.3%-19.4%109.6%-36.8%46.2%
12M Rtn31.3%208.6%746.5%42.4%393.7%-8.0%125.5%
3Y Rtn12.1%-85.0%574.0%-32.0%36.9%-6.8%2.6%
1M Excs Rtn-6.4%-8.7%-2.8%-3.0%18.2%-21.4%-4.7%
3M Excs Rtn-30.4%54.3%75.3%-6.1%47.8%-16.9%20.8%
6M Excs Rtn-32.9%165.1%86.0%-37.2%87.1%-54.0%26.5%
12M Excs Rtn11.4%197.7%839.7%28.9%394.6%-29.6%113.3%
3Y Excs Rtn-54.5%-168.8%553.0%-118.5%-43.4%-57.3%-55.9%

Comparison Analyses

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Financials

Segment Financials

Revenue by Segment
$ Mil20252024202320222021
Research and development for oncology-focused precision medicine  512820
Total  512820


Assets by Segment
$ Mil20252024202320222021
Research and development for oncology-focused precision medicine1,124649   
Total1,124649   


Price Behavior

Price Behavior
Market Price$27.87 
Market Cap ($ Bil)2.5 
First Trading Date05/23/2019 
Distance from 52W High-26.4% 
   50 Days200 Days
DMA Price$30.25$30.93
DMA Trendupdown
Distance from DMA-7.9%-9.9%
 3M1YR
Volatility44.5%45.7%
Downside Capture219.18146.85
Upside Capture53.68134.14
Correlation (SPY)39.9%32.7%
IDYA Betas & Captures as of 5/31/2026

 1M2M3M6M1Y3Y
Beta0.951.521.261.031.271.14
Up Beta2.151.661.851.701.821.08
Down Beta1.641.370.14-0.170.050.83
Up Capture32%24%83%74%194%190%
Bmk +ve Days13283667141432
Stock +ve Days8162855123377
Down Capture49%355%174%148%133%109%
Bmk -ve Days7132757109318
Stock -ve Days11243468124369

[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with IDYA
IDYA45.4%46.0%0.95-
Sector ETF (XLV)12.4%14.6%0.5836.3%
Equity (SPY)30.5%11.8%1.9532.1%
Gold (GLD)35.9%26.7%1.126.8%
Commodities (DBC)44.5%18.9%1.81-9.6%
Real Estate (VNQ)10.1%13.2%0.4721.9%
Bitcoin (BTCUSD)-32.2%41.6%-0.8218.0%

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Based On 5-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with IDYA
IDYA8.0%59.0%0.36-
Sector ETF (XLV)5.0%14.7%0.1628.7%
Equity (SPY)14.2%17.0%0.6630.6%
Gold (GLD)18.3%18.0%0.832.9%
Commodities (DBC)10.4%19.4%0.421.8%
Real Estate (VNQ)2.9%18.8%0.0625.3%
Bitcoin (BTCUSD)13.0%54.6%0.4316.0%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 10-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with IDYA
IDYA9.9%73.9%0.50-
Sector ETF (XLV)9.6%16.5%0.4725.7%
Equity (SPY)15.9%17.9%0.7626.7%
Gold (GLD)13.2%16.0%0.685.4%
Commodities (DBC)7.5%17.9%0.347.0%
Real Estate (VNQ)5.5%20.7%0.2322.9%
Bitcoin (BTCUSD)66.0%66.9%1.0512.5%

Smart multi-asset allocation framework can stack odds in your favor. Learn How

Short Interest

Short Interest: As Of Date5152026
Short Interest: Shares Quantity11.7 Mil
Short Interest: % Change Since 4302026-0.0%
Average Daily Volume0.8 Mil
Days-to-Cover Short Interest14.0 days
Basic Shares Quantity88.7 Mil
Short % of Basic Shares13.2%

Earnings Returns History

Updated 6/3/2026
Expand for More
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
5/5/2026-0.3%-2.7%-3.6%
2/17/20261.6%6.1%13.2%
11/4/2025-2.8%-1.5%14.8%
8/5/2025-3.5%-8.6%3.0%
5/6/2025-13.3%-10.4%3.1%
2/13/2025-5.4%-1.0%-15.4%
11/4/20244.9%9.4%-6.8%
8/6/2024-2.7%1.6%4.1%
...
SUMMARY STATS   
# Positive101014
# Negative141410
Median Positive2.7%1.8%11.1%
Median Negative-2.5%-3.0%-10.1%
Max Positive14.6%26.0%52.7%
Max Negative-34.8%-34.8%-20.0%

SEC Filings

Expand for More
Report DateFiling DateFiling
03/31/202605/05/202610-Q
12/31/202502/17/202610-K
09/30/202511/04/202510-Q
06/30/202508/05/202510-Q
03/31/202505/06/202510-Q
12/31/202402/18/202510-K
09/30/202411/04/202410-Q
06/30/202408/06/202410-Q
03/31/202405/07/202410-Q
12/31/202302/20/202410-K
09/30/202311/07/202310-Q
06/30/202308/10/202310-Q
03/31/202305/09/202310-Q
12/31/202203/07/202310-K
09/30/202211/08/202210-Q
06/30/202208/15/202210-Q

Insider Activity

Updated 4/26/2026
Expand for More
#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Stein, Jeffrey DirectBuy302202632.9650,0001,647,8901,788,982Form
Core Cache Last Updated: 6/2/2026