Tearsheet

NRX Pharmaceuticals (NRXP)


Market Price (3/21/2026): $1.85 | Market Cap: $41.1 Mil
Sector: Health Care | Industry: Biotechnology

NRX Pharmaceuticals (NRXP)


Market Price (3/21/2026): $1.85
Market Cap: $41.1 Mil
Sector: Health Care
Industry: Biotechnology

Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.

0 Megatrend and thematic drivers
Megatrends include Precision Medicine. Themes include CNS Targeted Therapies, and Critical Care Drug Development.
Weak multi-year price returns
2Y Excs Rtn is -87%, 3Y Excs Rtn is -140%
Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -14 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -5757%
1  Meaningful short interest
Short Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 11%
Expensive valuation multiples
P/SPrice/Sales ratio is 170x
2   Significant share based compensation
SBC/Rev LTMShare Based Compensation / Revenue (Sales), Last Twelve Months (LTM) is 79%
3   Not cash flow generative
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -5164%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -5164%
4   Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -97%
5   Key risks
NRXP key risks include [1] substantial doubt about its ability to continue as a going concern due to persistent net losses and a heavy reliance on raising capital, Show more.
0 Megatrend and thematic drivers
Megatrends include Precision Medicine. Themes include CNS Targeted Therapies, and Critical Care Drug Development.
1 Weak multi-year price returns
2Y Excs Rtn is -87%, 3Y Excs Rtn is -140%
2 Meaningful short interest
Short Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 11%
3 Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -14 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -5757%
4 Expensive valuation multiples
P/SPrice/Sales ratio is 170x
5 Significant share based compensation
SBC/Rev LTMShare Based Compensation / Revenue (Sales), Last Twelve Months (LTM) is 79%
6 Not cash flow generative
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -5164%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -5164%
7 Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -97%
8 Key risks
NRXP key risks include [1] substantial doubt about its ability to continue as a going concern due to persistent net losses and a heavy reliance on raising capital, Show more.

Valuation, Metrics & Events

Price Chart

Why The Stock Moved

Qualitative Assessment

AI Analysis | Feedback

NRX Pharmaceuticals (NRXP) stock has lost about 25% since 11/30/2025 because of the following key factors:

1. NRx Pharmaceuticals reported a significant earnings miss for Q3 2025 and an increased operating loss.

On November 17, 2025, the company announced Q3 2025 earnings per share (EPS) of -$0.18, missing analysts' consensus estimates of -$0.11 by $0.07. Additionally, quarterly revenue was reported at $0.24 million, significantly below analyst estimates of $6.83 million. The company's operating loss also increased to $4 million, up from $3 million in Q3 2024. This poor financial performance led to a 15.3% decline in the stock price the day following the earnings announcement.

2. Shareholders experienced substantial dilution in the past year.

Total shares outstanding for NRx Pharmaceuticals grew by 88.8% in the past year. This significant increase in the number of shares has a dilutive effect, reducing the value of existing shareholders' equity.

Show more

Stock Movement Drivers

Fundamental Drivers

The -24.5% change in NRXP stock from 11/30/2025 to 3/20/2026 was primarily driven by a -24.5% change in the company's P/S Multiple.
(LTM values as of)113020253202026Change
Stock Price ($)2.451.85-24.5%
Change Contribution By: 
Total Revenues ($ Mil)000.0%
P/S Multiple225.1169.9-24.5%
Shares Outstanding (Mil)22220.0%
Cumulative Contribution-24.5%

LTM = Last Twelve Months as of date shown

Market Drivers

11/30/2025 to 3/20/2026
ReturnCorrelation
NRXP-24.5% 
Market (SPY)-4.8%37.3%
Sector (XLV)-7.8%16.1%

Fundamental Drivers

The -20.3% change in NRXP stock from 8/31/2025 to 3/20/2026 was primarily driven by a null change in the company's P/S Multiple.
(LTM values as of)83120253202026Change
Stock Price ($)2.321.85-20.3%
Change Contribution By: 
Total Revenues ($ Mil)009.2233720368547763E17%
P/S Multiple169.9 
Shares Outstanding (Mil)1822-19.3%
Cumulative Contribution0.0%

LTM = Last Twelve Months as of date shown

Market Drivers

8/31/2025 to 3/20/2026
ReturnCorrelation
NRXP-20.3% 
Market (SPY)1.1%36.4%
Sector (XLV)6.2%18.7%

Fundamental Drivers

The -18.5% change in NRXP stock from 2/28/2025 to 3/20/2026 was primarily driven by a null change in the company's P/S Multiple.
(LTM values as of)22820253202026Change
Stock Price ($)2.271.85-18.5%
Change Contribution By: 
Total Revenues ($ Mil)009.2233720368547763E17%
P/S Multiple169.9 
Shares Outstanding (Mil)1122-50.6%
Cumulative Contribution0.0%

LTM = Last Twelve Months as of date shown

Market Drivers

2/28/2025 to 3/20/2026
ReturnCorrelation
NRXP-18.5% 
Market (SPY)10.4%30.2%
Sector (XLV)-1.1%21.7%

Fundamental Drivers

The -81.9% change in NRXP stock from 2/28/2023 to 3/20/2026 was primarily driven by a null change in the company's P/S Multiple.
(LTM values as of)22820233202026Change
Stock Price ($)10.201.85-81.9%
Change Contribution By: 
Total Revenues ($ Mil)009.2233720368547763E17%
P/S Multiple169.9 
Shares Outstanding (Mil)722-70.1%
Cumulative Contribution0.0%

LTM = Last Twelve Months as of date shown

Market Drivers

2/28/2023 to 3/20/2026
ReturnCorrelation
NRXP-81.9% 
Market (SPY)70.3%3.2%
Sector (XLV)19.6%2.2%

Return vs. Risk

Price Returns Compared

 202120222023202420252026Total [1]
Returns
NRXP Return-80%-77%-59%-52%23%-32%-99%
Peers Return25%32%3%10%47%-2%169%
S&P 500 Return27%-19%24%23%16%-3%76%

Monthly Win Rates [3]
NRXP Win Rate42%50%42%25%50%0% 
Peers Win Rate63%62%45%50%62%47% 
S&P 500 Win Rate75%42%67%75%67%33% 

Max Drawdowns [4]
NRXP Max Drawdown-82%-89%-79%-75%-22%-38% 
Peers Max Drawdown-18%-19%-24%-7%-9%-8% 
S&P 500 Max Drawdown-1%-25%-1%-2%-15%-3% 


[1] Cumulative total returns since the beginning of 2021
[2] Peers: AXSM, JNJ, LLY, ABBV, PFE.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 3/20/2026 (YTD)

How Low Can It Go

Unique KeyEventNRXPS&P 500
2022 Inflation Shock2022 Inflation Shock  
2022 Inflation Shock% Loss% Loss-99.6%-25.4%
2022 Inflation Shock% Gain to Breakeven% Gain to Breakeven26965.2%34.1%
2022 Inflation ShockTime to BreakevenTime to BreakevenNot Fully Recovered days464 days
2020 Covid Pandemic2020 Covid Pandemic  
2020 Covid Pandemic% Loss% Loss-36.4%-33.9%
2020 Covid Pandemic% Gain to Breakeven% Gain to Breakeven57.2%51.3%
2020 Covid PandemicTime to BreakevenTime to Breakeven20 days148 days
2018 Correction2018 Correction  
2018 Correction% Loss% Loss-4.6%-19.8%
2018 Correction% Gain to Breakeven% Gain to Breakeven4.9%24.7%
2018 CorrectionTime to BreakevenTime to Breakeven169 days120 days

Compare to AXSM, JNJ, LLY, ABBV, PFE

In The Past

NRX Pharmaceuticals's stock fell -99.6% during the 2022 Inflation Shock from a high on 2/2/2021. A -99.6% loss requires a 26965.2% gain to breakeven.

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About NRX Pharmaceuticals (NRXP)

NRX Pharmaceuticals, Inc., a clinical-stage pharmaceutical company, develops novel therapeutics for the treatment of central nervous system disorders and life-threatening pulmonary diseases. Its products include ZYESAMI, an investigational drug that has completed a Phase IIb/III clinical study for COVID-19 related respiratory failure; and NRX-100 and NRX-101 oral therapeutics for the treatment of bipolar depression in patients with acute suicidal behavior/ideation and sub-acute suicidal ideation and behavior. The company was founded in 2015 and is based in Wilmington, Delaware.

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  • A clinical-stage biotech striving to be the next Moderna or Gilead, specializing in mental health and critical respiratory drugs.
  • Like a biomedical Google X, dedicated to discovering innovative drugs for mental health disorders and critical lung diseases.

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  • ZYESAMI: An investigational drug developed for COVID-19 related respiratory failure.
  • NRX-100: An oral therapeutic targeting bipolar depression in patients exhibiting acute suicidal behavior or ideation.
  • NRX-101: An oral therapeutic for the treatment of bipolar depression in patients with sub-acute suicidal ideation and behavior.

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Jonathan C. Javitt, M.D., M.P.H. Chief Executive Officer, Chairman, and Chief Scientist

Dr. Jonathan C. Javitt is the co-founder, Chairman, and Chief Scientist of NRx Pharmaceuticals, and currently serves as its CEO. He has founded seven successful healthcare IT and biopharma startups that have achieved public exits. Dr. Javitt has also led drug-development engagements for prominent pharmaceutical companies including Merck, Allergan, Pharmacia, Novartis, and Pfizer. He held healthcare leadership roles under Presidents Reagan, George H.W. Bush, Clinton, and George W. Bush, notably chairing the Health Committee of the President's Information Technology Advisory Committee (PITAC) and guiding the development of Executive Order 13335, which established the Office of the National Coordinator for Health IT.

Michael Abrams Chief Financial Officer

Michael Abrams was appointed Chief Financial Officer of NRx Pharmaceuticals in November 2024. He possesses nearly three decades of experience as an executive officer, investment banker, director, and senior advisor. His prior experience as CFO includes roles at Arch Therapeutics, RiseIT Solutions, and FitLife Brands. Mr. Abrams' expertise encompasses financial operations, accounting, mergers and acquisitions, financial engineering, capital raising, and shareholder communications.

Daniel C. Javitt, M.D., Ph.D. Co-Founder and Chair of the Scientific Advisory Board

Dr. Daniel C. Javitt is a co-founder of NRx Pharmaceuticals and serves as the Chair of its Scientific Advisory Board. He is a Professor of Psychiatry and Neuroscience at Columbia University. With over 30 years dedicated to the intersection of psychiatry and brain science, his research focuses on NMDA receptors and their role in psycho-affective disorders. Dr. Javitt is credited with discovering the synergy between NMDA antagonist drugs and serotonin-targeted compounds, a foundational element of NRx Pharmaceuticals' technology platform. He has authored over 250 scientific publications and holds 10 patents in the field.

Robert Besthof Head of Operations and Chief Commercial Officer

Robert Besthof currently serves as the Head of Operations and Chief Commercial Officer for NRx Pharmaceuticals. He previously held the position of interim CEO before Stephen Willard's appointment in July 2022.

Prof. Joshua C. Brown, MD, PhD Chief Medical Innovation Officer

Prof. Joshua C. Brown was appointed Chief Medical Innovation Officer of NRx Pharmaceuticals in March 2026. He is a psychiatrist, neurologist, and neuroscientist with a focus on Transcranial Magnetic Stimulation (TMS). Prof. Brown is the current President of the Clinical TMS Society and Editor-in-Chief of the Transcranial Magnetic Stimulation journal. His background includes extensive work on neuroplasticity and its application to treating depression and PTSD.

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Key Risks to NRX Pharmaceuticals (NRXP)

  1. Financial Sustainability and Going Concern Risk

    NRX Pharmaceuticals faces significant challenges related to its financial viability. The company has a history of substantial operating losses, a large accumulated deficit, and negative shareholder equity. Its current cash position indicates a short cash runway, and management has explicitly expressed substantial doubt about the company's ability to continue as a going concern. While the company has secured operating capital through mid-2026 and recently repaid some debt, the underlying issue of consistent profitability and sufficient cash flow remains a primary concern.

  2. Regulatory Approval and Clinical Development Risks

    As a clinical-stage pharmaceutical company, the success of NRX Pharmaceuticals is heavily dependent on the successful development and regulatory approval of its drug candidates. There are inherent uncertainties in the FDA approval process, which could lead to delays or outright denial of marketing authorization for its lead drug candidates, NRX-100, NRX-101, and ZYESAMI. For example, ZYESAMI, an investigational drug for COVID-11 related respiratory failure, previously had its Emergency Use Authorization declined by the FDA due to insufficient data. While NRX-100 and NRX-101 are progressing through clinical development with recent positive FDA feedback for NRX-100, the path to final approval still carries significant risk.

  3. Nasdaq Delisting Risk

    NRX Pharmaceuticals has previously faced non-compliance issues with Nasdaq's continued listing requirements, specifically concerning its Market Value of Listed Securities (MVLS). Failure to maintain compliance with these requirements could result in the delisting of its common stock. A delisting would likely have a negative impact on the company's ability to raise additional capital and could significantly reduce the liquidity and market price of its shares.

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The rapidly diminishing and evolving market for COVID-19 therapeutics poses a clear emerging threat to the commercial potential of ZYESAMI. With widespread vaccination, the availability of established treatments, and a general decline in the severity and hospitalization rates associated with new variants, the addressable market for a new drug targeting COVID-19 related respiratory failure, even one that has completed late-stage clinical studies, is significantly reduced compared to earlier stages of the pandemic. This shift in market demand and the competitive landscape could severely limit the drug's future revenue generation.

AI Analysis | Feedback

NRX Pharmaceuticals (symbol: NRXP) is a clinical-stage pharmaceutical company developing therapeutics for central nervous system disorders and life-threatening pulmonary diseases. The addressable markets for its main products are as follows:

  • ZYESAMI (COVID-19 related respiratory failure): The addressable market size for ZYESAMI for COVID-19 related respiratory failure is currently null, as specific market sizing information was not identified in the provided data.
  • NRX-100 (IV ketamine for suicidal depression): The addressable market for NRX-100, a preservative-free intravenous ketamine for suicidal depression, is estimated to be between $3 billion and $5 billion in the U.S.
  • NRX-101 (oral therapeutics for bipolar depression with suicidal ideation and behavior): The addressable market for NRX-101, an oral therapeutic for bipolar depression, is estimated to be over $2 billion for its initial indication in patients at risk of akathisia, with the broad bipolar market potentially exceeding $5 billion in the U.S. If approved, the market for NRx-101 combined with transcranial magnetic stimulation (TMS) for depression and suicidality could exceed $1 billion. Furthermore, an estimated initial market of $3.7 billion in the U.S. is noted for NRX-101 addressing bipolar depression in patients with akathisia.

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NRX Pharmaceuticals (NRXP) is positioned for future revenue growth over the next 2-3 years, driven primarily by the potential commercialization of its central nervous system disorder therapeutics and the expansion of its clinical services network. Key expected drivers include:

  1. Commercialization of KETAFREE (NRX-100) via Abbreviated New Drug Application (ANDA) Pathway: NRx Pharmaceuticals has refiled its Abbreviated New Drug Application (ANDA) for KETAFREE, a preservative-free ketamine formulation, with an anticipated Goal Date for review by the second quarter of 2026. The existing generic ketamine market is estimated at approximately $750 million annually, and NRx Pharmaceuticals expects to secure a substantial share of this market upon approval. The company aims to have at least one million doses manufactured and ready for distribution by July 2026.
  2. Approval and Commercialization of NRX-101 for Suicidal Bipolar Depression: NRX-101, which holds Breakthrough Therapy Designation for suicidal bipolar depression, is progressing through its New Drug Application (NDA) filing, with a Prescription Drug User Fee Act (PDUFA) date anticipated before December 31, 2025. If approved, NRX-101 could address a significant unmet medical need for patients with acute suicidal ideation and behavior in bipolar depression.
  3. Expansion of HOPE Therapeutics Clinic Network and NRX-101 Augmentation of TMS: HOPE Therapeutics, a wholly-owned subsidiary, has initiated revenue generation from its interventional psychiatry clinics in Florida, with plans to expand its network. This expansion provides a direct revenue stream from patient services. Additionally, new real-world data indicate that NRX-101 may significantly enhance the effectiveness of Transcranial Magnetic Stimulation (TMS), potentially doubling its antidepressant and antisuicidal effects. NRx Pharmaceuticals plans a confirmatory Phase 3 trial for NRX-101 in conjunction with TMS in early 2026, targeting a potential market exceeding $1 billion for this new indication.
  4. New Drug Application (NDA) for NRX-100 (ketamine) for Suicidal Depression: NRx Pharmaceuticals is pursuing an innovative New Drug Application (NDA) pathway for NRX-100 (ketamine) under FDA Fast Track designation, aiming for a broader indication that includes suicidal ideation in depression. Following a Type C FDA meeting, the company confirmed a path to NDA submission by June 2026, utilizing existing clinical trial data alongside Real World Evidence. This innovative approach could establish NRX-100 as a treatment specifically addressing suicidal ideation in depressed patients.

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Share Issuance

  • NRX Pharmaceuticals filed a prospectus for an at-the-market (ATM) stock offering of up to $20,000,000 of its common stock.
  • The company raised approximately $1.7 million and $2.4 million through public offerings in February and April 2024, respectively.
  • On August 18, 2025, a consortium led by B Group Capital invested $6.5 million for approximately 3.9 million shares of common stock.

Inbound Investments

  • NRx Pharmaceuticals signed a development partnership with Alvogen and Lotus Pharmaceuticals, where partners committed to taking over phase 3 and commercial costs for NRX-101 and funding $330 million in commercial milestones, along with a double-digit royalty on sales.
  • The company received a $5.1 million advance against milestones from Alvogen and Lotus Pharmaceuticals.
  • NRx Pharmaceuticals secured $18.7 million in financing activities during the third quarter of 2025.

Outbound Investments

  • NRX Pharmaceuticals, through its subsidiary Hope Therapeutics, acquired a strategic interest in Cohen, LLC on October 17, 2025.
  • Hope Therapeutics entered into agreements for the acquisition of Kadima Neuroscience Institute, Dura Medical, and Neurospa TMS Holdings, which are expected to represent approximately $15 million in forward-looking pro-forma revenues.
  • The company received approval for $7.8 million of debt financing to support the acquisition of Dura Medical, NeuroSpa TMS Holdings, and Cohen and Associates.

Capital Expenditures

  • Research and Development (R&D) expenses increased by $800,000 in the third quarter of 2025 compared to the third quarter of 2024, primarily to support FDA initiatives for NRX-100 and NRX-101.
  • General and Administrative (G&A) expenses climbed by $400,000 in the third quarter of 2025, which included costs related to identifying, closing, and operating new clinic acquisition targets for the Hope Therapeutics network.
  • Research and Development expenses were reduced from $13.4 million in 2023 to $6.2 million in 2024, mainly due to the conclusion of the Phase 2 study for NRX-101 and cash conservation efforts.

Latest Trefis Analyses

TitleDate
0DASHBOARDS 
1NRX Pharmaceuticals Earnings Notes12/16/2025
Title
0ARTICLES

Trade Ideas

Select ideas related to NRXP.

Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
QDEL_2282026_Insider_Buying_45D_2Buy_200K02282026QDELQuidelOrthoInsiderInsider Buys 45DStrong Insider Buying
Companies with multiple insider buys in the last 45 days
0.0%0.0%0.0%
CHE_2272026_Dip_Buyer_FCFYield02272026CHEChemedDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
0.0%0.0%0.0%
LLY_2272026_Monopoly_xInd_xCD_Getting_Cheaper02272026LLYEli LillyMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
0.0%0.0%0.0%
HAE_2202026_Dip_Buyer_FCFYield02202026HAEHaemoneticsDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
3.5%3.5%0.0%
IQV_2132026_Dip_Buyer_ValueBuy02132026IQVIQVIADip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
7.1%7.1%-3.0%

Recent Active Movers

Peer Comparisons

Peers to compare with:

Financials

NRXPAXSMJNJLLYABBVPFEMedian
NameNRX Phar.Axsome T.Johnson .Eli LillyAbbVie Pfizer  
Mkt Price1.85156.92235.37906.70205.0726.97181.00
Mkt Cap0.07.9566.7812.2362.8153.4258.1
Rev LTM063894,19365,17961,16062,57961,870
Op Inc LTM-14-16925,59629,69620,09117,40618,748
FCF LTM-12-9419,3135,96417,8169,0757,520
FCF 3Y Avg-17-12318,3831,07519,2377,9014,488
CFO LTM-12-9324,53016,81319,03011,70414,258
CFO 3Y Avg-17-12223,8629,95720,22511,04910,503

Growth & Margins

NRXPAXSMJNJLLYABBVPFEMedian
NameNRX Phar.Axsome T.Johnson .Eli LillyAbbVie Pfizer  
Rev Chg LTM-65.5%6.0%44.7%8.6%-1.6%8.6%
Rev Chg 3Y Avg-183.0%2.6%32.1%1.9%-12.0%2.6%
Rev Chg Q-65.0%9.1%42.6%10.0%-1.2%10.0%
QoQ Delta Rev Chg LTM-13.8%2.2%9.7%2.5%-0.3%2.5%
Op Mgn LTM-5,757.4%-26.5%27.2%45.6%32.8%27.8%27.5%
Op Mgn 3Y Avg--53.2%25.6%37.9%26.3%19.6%25.6%
QoQ Delta Op Mgn LTM-8.2%1.5%1.1%8.8%0.9%1.5%
CFO/Rev LTM-5,164.0%-14.6%26.0%25.8%31.1%18.7%22.2%
CFO/Rev 3Y Avg--33.8%26.7%19.3%35.5%17.8%19.3%
FCF/Rev LTM-5,164.0%-14.7%20.5%9.2%29.1%14.5%11.8%
FCF/Rev 3Y Avg--34.0%20.6%0.3%33.8%12.7%12.7%

Valuation

NRXPAXSMJNJLLYABBVPFEMedian
NameNRX Phar.Axsome T.Johnson .Eli LillyAbbVie Pfizer  
Mkt Cap0.07.9566.7812.2362.8153.4258.1
P/S169.912.46.012.55.92.59.2
P/EBIT-1.1-44.916.927.438.215.016.0
P/E-1.1-43.421.139.485.819.720.4
P/CFO-3.3-85.123.148.319.113.116.1
Total Yield-92.5%-2.3%6.9%3.2%4.4%11.4%3.8%
Dividend Yield0.0%0.0%2.2%0.7%3.2%6.4%1.4%
FCF Yield 3Y Avg-25.5%-2.7%4.6%0.0%6.0%5.3%2.3%
D/E0.30.00.10.10.20.40.1
Net D/E0.1-0.00.00.00.20.30.1

Returns

NRXPAXSMJNJLLYABBVPFEMedian
NameNRX Phar.Axsome T.Johnson .Eli LillyAbbVie Pfizer  
1M Rtn4.2%-15.1%-3.9%-11.2%-10.3%-1.5%-7.1%
3M Rtn-21.9%2.8%14.7%-15.2%-8.9%8.9%-3.0%
6M Rtn-37.7%35.3%35.2%21.0%-6.4%16.1%18.5%
12M Rtn-10.6%24.3%48.4%8.4%-0.0%10.5%9.4%
3Y Rtn-72.8%149.6%67.2%180.0%45.8%-20.5%56.5%
1M Excs Rtn5.7%-10.5%0.5%-6.2%-3.4%5.6%-1.5%
3M Excs Rtn-15.7%9.2%15.7%-9.6%-4.6%12.7%2.3%
6M Excs Rtn-36.0%34.2%38.6%21.1%-4.3%17.4%19.3%
12M Excs Rtn-29.8%10.0%33.8%-5.5%-14.8%-4.3%-4.9%
3Y Excs Rtn-140.0%86.2%-0.4%114.2%-18.8%-86.9%-9.6%

Comparison Analyses

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Financials

Segment Financials

Assets by Segment
$ Mil2024202320222021
Development of novel therapeutics for the treatment of central nervous system disorders including726333
Total726333


Price Behavior

Price Behavior
Market Price$1.85 
Market Cap ($ Bil)0.0 
First Trading Date12/04/2017 
Distance from 52W High-49.6% 
   50 Days200 Days
DMA Price$1.96$2.61
DMA Trenddowndown
Distance from DMA-5.8%-29.2%
 3M1YR
Volatility73.4%74.4%
Downside Capture248.11196.88
Upside Capture166.52154.97
Correlation (SPY)50.9%30.5%
NRXP Betas & Captures as of 2/28/2026

 1M2M3M6M1Y3Y
Beta5.333.332.592.211.160.97
Up Beta6.376.605.763.230.781.00
Down Beta3.862.382.352.551.053.73
Up Capture577%142%91%137%171%46%
Bmk +ve Days9203170142431
Stock +ve Days9172755114343
Down Capture496%362%243%190%141%111%
Bmk -ve Days12213054109320
Stock -ve Days10203064126384

[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with NRXP
NRXP-16.5%74.5%0.07-
Sector ETF (XLV)0.2%17.6%-0.1424.0%
Equity (SPY)15.8%18.9%0.6430.4%
Gold (GLD)48.2%27.0%1.458.7%
Commodities (DBC)17.8%17.4%0.8317.2%
Real Estate (VNQ)1.0%16.4%-0.1116.2%
Bitcoin (BTCUSD)-19.0%44.2%-0.3538.1%

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Based On 5-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with NRXP
NRXP-63.6%381.0%0.33-
Sector ETF (XLV)6.3%14.5%0.264.1%
Equity (SPY)11.8%17.0%0.544.9%
Gold (GLD)20.7%17.5%0.974.9%
Commodities (DBC)10.9%19.0%0.462.5%
Real Estate (VNQ)2.8%18.8%0.064.5%
Bitcoin (BTCUSD)4.7%56.7%0.306.9%

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Based On 10-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with NRXP
NRXP-33.7%355.1%0.37-
Sector ETF (XLV)9.6%16.5%0.473.5%
Equity (SPY)14.2%17.9%0.684.6%
Gold (GLD)13.3%15.7%0.704.2%
Commodities (DBC)8.3%17.6%0.391.8%
Real Estate (VNQ)5.0%20.7%0.214.4%
Bitcoin (BTCUSD)66.9%66.8%1.066.4%

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Short Interest

Short Interest: As Of Date2272026
Short Interest: Shares Quantity2.5 Mil
Short Interest: % Change Since 2152026-8.4%
Average Daily Volume0.5 Mil
Days-to-Cover Short Interest4.7 days
Basic Shares Quantity22.2 Mil
Short % of Basic Shares11.1%

Earnings Returns History

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 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
8/18/2025-9.2%-2.5%5.8%
3/21/2025-0.5%-2.4%-8.2%
11/15/20249.2%5.9%37.8%
8/15/2024-0.6%17.2%-1.7%
4/2/2024-90.5%-89.6%-95.1%
11/14/20234.3%-7.3%-1.5%
3/31/2023-10.6%-21.4%-22.5%
11/14/2022-10.0%14.0%10.0%
SUMMARY STATS   
# Positive233
# Negative655
Median Positive6.8%14.0%10.0%
Median Negative-9.6%-7.3%-8.2%
Max Positive9.2%17.2%37.8%
Max Negative-90.5%-89.6%-95.1%

SEC Filings

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Report DateFiling DateFiling
09/30/202511/14/202510-Q
06/30/202508/18/202510-Q
03/31/202505/15/202510-Q
12/31/202403/14/202510-K
09/30/202411/14/202410-Q
06/30/202408/14/202410-Q
03/31/202405/14/202410-Q
12/31/202303/29/202410-K
09/30/202311/14/202310-Q
06/30/202308/14/202310-Q
03/31/202305/15/202310-Q
12/31/202203/31/202310-K
09/30/202211/14/202210-Q
06/30/202208/15/202210-Q
03/31/202205/16/202210-Q
12/31/202103/31/202210-K