Tearsheet

Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.

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Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -65%

Strong revenue growth
Rev Chg LTMRevenue Change % Last Twelve Months (LTM) is 105%

Valuation becoming less expensive
P/S 6M Chg %Price/Sales change over 6 months. Declining P/S indicates valuation has become less expensive. is -47%

Megatrend and thematic drivers
Megatrends include Precision Medicine, and Aging Population & Chronic Disease. Themes include Biopharmaceutical R&D, Targeted Therapies, Show more.

Weak multi-year price returns
2Y Excs Rtn is -93%, 3Y Excs Rtn is -108%

Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -94 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -230461%

Expensive valuation multiples
P/SPrice/Sales ratio is 8,956x

Significant share based compensation
SBC/Rev LTMShare Based Compensation / Revenue (Sales), Last Twelve Months (LTM) is 39210%

Not cash flow generative
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -164720%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -164722%

Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -28%

Significant short interest
Short Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 28%

Key risks
ALT key risks include [1] the uncertain clinical and regulatory outcome for its lead candidate, Show more.

0 Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -65%
1 Strong revenue growth
Rev Chg LTMRevenue Change % Last Twelve Months (LTM) is 105%
2 Valuation becoming less expensive
P/S 6M Chg %Price/Sales change over 6 months. Declining P/S indicates valuation has become less expensive. is -47%
3 Megatrend and thematic drivers
Megatrends include Precision Medicine, and Aging Population & Chronic Disease. Themes include Biopharmaceutical R&D, Targeted Therapies, Show more.
4 Weak multi-year price returns
2Y Excs Rtn is -93%, 3Y Excs Rtn is -108%
5 Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -94 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -230461%
6 Expensive valuation multiples
P/SPrice/Sales ratio is 8,956x
7 Significant share based compensation
SBC/Rev LTMShare Based Compensation / Revenue (Sales), Last Twelve Months (LTM) is 39210%
8 Not cash flow generative
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -164720%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -164722%
9 Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -28%
10 Significant short interest
Short Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 28%
11 Key risks
ALT key risks include [1] the uncertain clinical and regulatory outcome for its lead candidate, Show more.

Valuation, Metrics & Events

Price Chart

Why The Stock Moved

Qualitative Assessment

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Altimmune (ALT) stock has lost about 5% since 12/31/2025 because of the following key factors:

1. Positive clinical developments for pemvidutide were largely counterbalanced by weaker financial results. Altimmune received FDA Breakthrough Therapy Designation for its lead candidate, pemvidutide, for metabolic dysfunction-associated steatohepatitis (MASH) on January 5, 2026. This followed positive 48-week data from its IMPACT Phase 2b trial in December 2025, which demonstrated statistically significant improvements in non-invasive tests of liver fibrosis and continued weight loss. However, these positive clinical catalysts were offset by the company's Q4 2025 earnings report on March 5, 2026, where Altimmune reported an earnings per share (EPS) loss of -$0.27, missing analysts' expectations of -$0.25 by 8.00%, and revenue of $30,000, significantly below the consensus estimate of $717,000. The stock subsequently declined by 17.9% the day after the earnings announcement.

2. Share dilution and substantial capital requirements for Phase 3 trials impacted investor sentiment. To fund the planned initiation of its costly Phase 3 clinical trial for pemvidutide in MASH in 2026, Altimmune completed a $75 million registered direct offering in January 2026. Further increasing the potential for future dilution, stockholders approved doubling the company's authorized common shares from 200 million to 400 million on April 16, 2026. These capital-raising activities, while essential for advancing its pipeline, tend to exert downward pressure on the stock price due to the increased number of outstanding shares.

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Stock Movement Drivers

Fundamental Drivers

The -16.3% change in ALT stock from 12/31/2025 to 4/22/2026 was primarily driven by a -51.7% change in the company's P/S Multiple.
(LTM values as of)123120254222026Change
Stock Price ($)3.613.02-16.3%
Change Contribution By: 
Total Revenues ($ Mil)00105.0%
P/S Multiple16,140.07,794.6-51.7%
Shares Outstanding (Mil)89106-15.5%
Cumulative Contribution-16.3%

LTM = Last Twelve Months as of date shown

Market Drivers

12/31/2025 to 4/22/2026
ReturnCorrelation
ALT-3.9% 
Market (SPY)-5.4%31.3%
Sector (XLV)-5.4%30.2%

Fundamental Drivers

The -19.9% change in ALT stock from 9/30/2025 to 4/22/2026 was primarily driven by a -49.2% change in the company's P/S Multiple.
(LTM values as of)93020254222026Change
Stock Price ($)3.773.02-19.9%
Change Contribution By: 
Total Revenues ($ Mil)00105.0%
P/S Multiple15,358.57,794.6-49.2%
Shares Outstanding (Mil)81106-23.0%
Cumulative Contribution-19.9%

LTM = Last Twelve Months as of date shown

Market Drivers

9/30/2025 to 4/22/2026
ReturnCorrelation
ALT-8.0% 
Market (SPY)-2.9%23.6%
Sector (XLV)5.6%24.1%

Fundamental Drivers

The -39.6% change in ALT stock from 3/31/2025 to 4/22/2026 was primarily driven by a -56.2% change in the company's P/S Multiple.
(LTM values as of)33120254222026Change
Stock Price ($)5.003.02-39.6%
Change Contribution By: 
Total Revenues ($ Mil)00105.0%
P/S Multiple17,808.07,794.6-56.2%
Shares Outstanding (Mil)71106-32.7%
Cumulative Contribution-39.6%

LTM = Last Twelve Months as of date shown

Market Drivers

3/31/2025 to 4/22/2026
ReturnCorrelation
ALT-30.6% 
Market (SPY)16.3%25.8%
Sector (XLV)1.6%26.4%

Fundamental Drivers

The -28.4% change in ALT stock from 3/31/2023 to 4/22/2026 was primarily driven by a -350.9% change in the company's P/S Multiple.
(LTM values as of)33120234222026Change
Stock Price ($)4.223.02-28.4%
Change Contribution By: 
Total Revenues ($ Mil)-00-160.3%
P/S Multiple-3,106.77,794.6-350.9%
Shares Outstanding (Mil)50106-52.7%
Cumulative Contribution-28.4%

LTM = Last Twelve Months as of date shown

Market Drivers

3/31/2023 to 4/22/2026
ReturnCorrelation
ALT-17.8% 
Market (SPY)63.3%26.0%
Sector (XLV)18.4%24.1%

Return vs. Risk

Price Returns Compared

 202120222023202420252026Total [1]
Returns
ALT Return-19%80%-32%-36%-50%-6%-70%
Peers Return18%78%22%35%29%-2%339%
S&P 500 Return27%-19%24%23%16%3%88%

Monthly Win Rates [3]
ALT Win Rate33%42%33%42%50%50% 
Peers Win Rate50%53%42%50%47%50% 
S&P 500 Win Rate75%42%67%75%67%50% 

Max Drawdowns [4]
ALT Max Drawdown-25%-57%-87%-51%-53%-20% 
Peers Max Drawdown-15%-26%-30%-10%-20%-14% 
S&P 500 Max Drawdown-1%-25%-1%-2%-15%-7% 


[1] Cumulative total returns since the beginning of 2021
[2] Peers: VKTX, MDGL, LLY, AMGN, PFE. See ALT Returns vs. Peers.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 4/22/2026 (YTD)

How Low Can It Go

Unique KeyEventALTS&P 500
2022 Inflation Shock2022 Inflation Shock  
2022 Inflation Shock% Loss% Loss-91.2%-25.4%
2022 Inflation Shock% Gain to Breakeven% Gain to Breakeven1036.0%34.1%
2022 Inflation ShockTime to BreakevenTime to BreakevenNot Fully Recovered days464 days
2020 Covid Pandemic2020 Covid Pandemic  
2020 Covid Pandemic% Loss% Loss-76.4%-33.9%
2020 Covid Pandemic% Gain to Breakeven% Gain to Breakeven324.5%51.3%
2020 Covid PandemicTime to BreakevenTime to BreakevenNot Fully Recovered days148 days
2018 Correction2018 Correction  
2018 Correction% Loss% Loss-99.6%-19.8%
2018 Correction% Gain to Breakeven% Gain to Breakeven26762.7%24.7%
2018 CorrectionTime to BreakevenTime to BreakevenNot Fully Recovered days120 days
2008 Global Financial Crisis2008 Global Financial Crisis  
2008 Global Financial Crisis% Loss% Loss-88.8%-56.8%
2008 Global Financial Crisis% Gain to Breakeven% Gain to Breakeven794.1%131.3%
2008 Global Financial CrisisTime to BreakevenTime to BreakevenNot Fully Recovered days1,480 days

Compare to VKTX, MDGL, LLY, AMGN, PFE

In The Past

Altimmune's stock fell -91.2% during the 2022 Inflation Shock from a high on 2/17/2021. A -91.2% loss requires a 1036.0% gain to breakeven.

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About Altimmune (ALT)

Altimmune, Inc., a clinical stage biopharmaceutical company, focuses on developing treatments for obesity and liver diseases. The company's lead product candidate, pemvidutide (proposed INN, formerly known as ALT-801), is a GLP-1/glucagon dual receptor agonist that is in Phase 1b trial for the treatment of obesity and non-alcoholic steatohepatitis. It is also developing HepTcell, an immunotherapeutic product candidate, which is in Phase 2 clinical trial for patients chronically infected with the hepatitis B virus. The company was formerly known as Vaxin Inc. and changed its name to Altimmune, Inc. in September 2015. Altimmune, Inc. was founded in 1997 is headquartered in Gaithersburg, Maryland.

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Here are 1-2 brief analogies for Altimmune (ALT):

  • Altimmune is like Eli Lilly or Novo Nordisk for next-generation obesity and liver disease treatments.
  • Altimmune is an early-stage biotech aiming to be the next Eli Lilly or Novo Nordisk in the metabolic disease space.

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  • Pemvidutide (ALT-801): A GLP-1/glucagon dual receptor agonist in clinical trials for treating obesity and non-alcoholic steatohepatitis.
  • HepTcell: An immunotherapeutic product candidate in clinical trials for patients with chronic hepatitis B virus infection.

AI Analysis | Feedback

Altimmune, Inc. (ALT) is a clinical-stage biopharmaceutical company focused on developing treatments for obesity and liver diseases. As a clinical-stage company, its primary activities involve research and development, including conducting clinical trials for its product candidates like pemvidutide and HepTcell.

At this stage, Altimmune does not have commercialized products on the market, and therefore, it does not have major customers in the traditional sense, whether they be other companies or individuals. The company's focus is on bringing its drug candidates through the development and regulatory approval process.

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Jerome Durso President, Chief Executive Officer and Chairman Of The Board

Jerome Durso was appointed President and Chief Executive Officer of Altimmune, Inc. effective January 1, 2026, while also retaining his role as Chairman of the Board. He has over 30 years of leadership experience in the life sciences industry.

Greg Weaver, MBA Chief Financial Officer

Greg Weaver joined Altimmune as Chief Financial Officer in November 2024. He brings over 25 years of finance experience across publicly-traded and privately-held life sciences companies. Prior to Altimmune, he was CFO of Cognito Therapeutics, and before that, CFO at atai Life Sciences (Nasdaq: ATAI), where he led a $225 million Initial Public Offering in 2021. Earlier in his career, he served as CFO at publicly-traded biotech companies including Sirna Therapeutics, which was acquired by Merck, and ILEX Oncology, which was acquired by Genzyme.

Linda M. Richardson, BA Chief Commercial Officer

Linda M. Richardson was appointed Chief Commercial Officer of Altimmune, Inc. effective September 16, 2025.

Christophe Arbet-Engels, M.D., Ph.D. Chief Medical Officer

Christophe Arbet-Engels was appointed Chief Medical Officer of Altimmune, Inc. effective October 1, 2025.

M. Scot Roberts, Ph.D. Chief Scientific Officer

Dr. Scot Roberts has served as the Chief Scientific Officer for Altimmune since December 2012. He has over two decades of experience managing scientific operations, leading research and drug development efforts for both small molecules and biologics, with a focus on viral vectors and antiviral therapies. Before joining Altimmune, Dr. Roberts was the Chief Scientific Officer for ImQuest BioSciences, Inc., where he was responsible for scientific operations and business development in cancer and antivirals. He also held several leadership positions at Wellstat Biologics Corporation, including Director of Research and Development.

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Here are the key risks to Altimmune's business:

  1. Clinical Development and Regulatory Risk for Pemvidutide: Altimmune's core business relies heavily on the successful clinical development, regulatory approval, and commercialization of its lead product candidate, pemvidutide. While pemvidutide has shown promising results in clinical trials and received FDA Breakthrough Therapy designation for Metabolic Dysfunction-Associated Steatohepatitis (MASH), there are inherent uncertainties. The Phase 2b IMPACT trial for MASH met the primary endpoint of MASH resolution but did not achieve fibrosis improvement at 24 weeks, necessitating longer duration trials. Additionally, earlier data for obesity raised safety concerns regarding gastrointestinal adverse events leading to discontinuations at higher doses. The company's plan to introduce dose titration in the upcoming Phase 3 MASH program, a change from its prior "no titration" strategy, could impact pemvidutide's tolerability and its competitive advantage. The high failure rate, potential for delays, and significant costs associated with clinical trials pose a continuous and substantial risk to Altimmune. The company's past decision to halt development of its HepTcell program due to insufficient efficacy in Phase 2 trials underscores the challenges and risks of drug development.
  2. Intense Competition and Market Positioning for Pemvidutide: The markets for obesity and MASH treatments are highly competitive and rapidly expanding. Pemvidutide, a GLP-1/glucagon dual receptor agonist, faces significant competition from established pharmaceutical companies and other developing GLP-1-based therapies. The increasing commoditization of GLP-1 therapies could erode pemvidutide's potential differentiation and pricing power. Altimmune's ability to secure strategic partnerships for the costly commercialization of pemvidutide, particularly for its planned Phase 3 MASH program, remains a concern, as the absence of such collaborations could hinder its market entry and success.
  3. Financial Risk and Need for Additional Funding: As a clinical-stage biopharmaceutical company with no commercial products, Altimmune consistently reports financial losses and rising expenses. Although the company maintains a strong cash position that is projected to fund operations into 2028, the advancement of pemvidutide into late-stage (Phase 3) clinical trials, especially for MASH, will require substantial capital. Analysts do not anticipate profitability for Altimmune in the near future, and a projected funding gap could necessitate future equity dilution or increased debt if strategic partnerships or other funding sources are not secured.

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Addressable Markets for Altimmune's Main Products:

Pemvidutide (Obesity)

  • Global: The global obesity treatment market was valued at approximately USD 15.74 billion in 2024 and is projected to reach around USD 98.26 billion by 2034.
  • U.S.: The U.S. obesity treatment market generated revenue of USD 11,194.0 million in 2024 and is expected to reach USD 48,498.2 million by 2030.

Pemvidutide (Non-alcoholic Steatohepatitis/Metabolic Dysfunction-Associated Steatohepatitis - NASH/MASH)

  • Global: The global Non-Alcoholic Steatohepatitis Treatment Market was valued at USD 7.70 billion in 2024 and is projected to reach USD 55.52 billion by 2032.
  • U.S.: The U.S. NASH treatment market accounted for approximately USD 4.56 billion in 2024 and is forecast to rise to USD 32.55 billion by 2032.

HepTcell (Chronic Hepatitis B Virus)

  • null

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Here are 3-5 expected drivers of future revenue growth for Altimmune (ALT) over the next 2-3 years:

  1. Advancement and Potential Commercialization of Pemvidutide in Metabolic Dysfunction-Associated Steatohepatitis (MASH): Altimmune plans to initiate a global Phase 3 MASH trial for pemvidutide in 2026, building on positive 24-week Phase 2b data that demonstrated significant MASH resolution without worsening of fibrosis, along with meaningful reductions in fibrosis and liver fat. The 48-week data from the IMPACT Phase 2b MASH trial is anticipated in the fourth quarter of 2025. The U.S. FDA has granted Fast Track designation to pemvidutide for the treatment of MASH. Successful progression through Phase 3 and potential accelerated approval could pave the way for market entry or lucrative partnerships, driving significant revenue.
  2. Advancement and Potential Commercialization of Pemvidutide in Obesity: Following successful End-of-Phase 2 meetings with the FDA in late 2024 to clarify the Phase 3 design, Altimmune is preparing for a Phase 3 obesity registrational program for pemvidutide. The program will include four pivotal trials focusing on weight loss and evaluating effects on comorbidities such as elevated serum lipids and liver fat. Pemvidutide's differentiated profile, including significant weight loss with class-leading preservation of lean mass (74.5% fat loss, 25.5% lean mass loss), positions it uniquely in the competitive obesity market. Future positive clinical trial outcomes could lead to commercial partnerships or market penetration, tapping into a global obesity market projected to reach $31.1 billion by 2031.
  3. Expansion of Pemvidutide into New Indications: Altimmune is exploring additional indications for pemvidutide, with plans to submit Investigational New Drug (IND) applications for up to three new areas starting in Q4 2024. Specifically, Phase 2 trials for pemvidutide in Alcohol Use Disorder (RECLAIM) and Alcohol-Associated Liver Disease (RESTORE) were initiated in May 2025 and July 2025, respectively. Topline results from the Phase 2 RECLAIM trial for AUD are anticipated in Q3 2026. Positive results in these areas could open up new significant markets for pemvidutide, diversifying future revenue streams beyond obesity and MASH.
  4. Strategic Partnerships and Licensing Deals for Pemvidutide: As a clinical-stage biopharmaceutical company with no current commercial revenue, Altimmune's future revenue growth is heavily reliant on securing strategic partnerships or licensing agreements for pemvidutide. Successful data readouts from its ongoing and upcoming Phase 2 and Phase 3 trials in MASH, obesity, and other indications are critical catalysts that could attract large pharmaceutical partners, leading to upfront payments, milestone payments, and royalties, thereby driving significant revenue growth.

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Capital Allocation Decisions (Last 3-5 Years)

Share Issuance

  • In January 2026, Altimmune closed a registered direct offering of common stock and pre-funded warrants, generating gross proceeds of approximately $75 million.
  • The company raised an additional $8.0 million through its At-the-Market (ATM) facility in January 2026.
  • During 2025, Altimmune recorded net equity capital raised totaling approximately $174 million.

Inbound Investments

  • Altimmune completed a $75 million registered direct offering in January 2026 with Alyeska Investment Group, a new fundamental institutional investor.
  • In 2025, the company received $35 million in funding from the Hercules tranche loan facility.

Capital Expenditures

  • Capital expenditures for the year ended December 31, 2025, were minimal, approximately $11K.
  • The company's capital expenditures are not a primary focus as it does not operate a large manufacturing infrastructure.
  • Future capital expenditures are expected to remain minimal, with the main spending concentrated on research and development for clinical trials.

Better Bets vs. Altimmune (ALT)

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Recent Active Movers

Peer Comparisons

Peers to compare with:

Financials

ALTVKTXMDGLLLYAMGNPFEMedian
NameAltimmuneViking T.Madrigal.Eli LillyAmgen Pfizer  
Mkt Price3.0234.23528.62919.90345.8526.82190.04
Mkt Cap0.33.912.1824.0186.1152.582.3
Rev LTM0095865,17936,75162,57918,855
Op Inc LTM-94-393-30029,6969,08017,4064,493
FCF LTM-68-279-1905,9648,1009,0752,948
FCF 3Y Avg-74-147-3261,0758,6187,901500
CFO LTM-68-279-19016,8139,95811,7044,945
CFO 3Y Avg-74-147-3239,9579,97311,0494,941

Growth & Margins

ALTVKTXMDGLLLYAMGNPFEMedian
NameAltimmuneViking T.Madrigal.Eli LillyAmgen Pfizer  
Rev Chg LTM105.0%-432.1%44.7%10.0%-1.6%44.7%
Rev Chg 3Y Avg245.4%--32.1%11.9%-12.0%22.0%
Rev Chg Q420.0%-210.8%42.6%8.6%-1.2%42.6%
QoQ Delta Rev Chg LTM105.0%-29.4%9.7%2.2%-0.3%9.7%
Op Inc Chg LTM8.4%-160.6%39.7%74.3%25.1%16.5%20.8%
Op Inc Chg 3Y Avg-3.4%-84.5%-6.9%54.7%-0.1%55.5%-1.8%
Op Mgn LTM-230,461.0%--31.3%45.6%24.7%27.8%24.7%
Op Mgn 3Y Avg-255,308.1%--37.9%24.8%19.6%22.2%
QoQ Delta Op Mgn LTM221,849.0%-10.2%1.1%0.6%0.9%1.1%
CFO/Rev LTM-164,719.5%--19.8%25.8%27.1%18.7%18.7%
CFO/Rev 3Y Avg-193,918.4%--19.3%30.5%17.8%18.5%
FCF/Rev LTM-164,722.0%--19.8%9.2%22.0%14.5%9.2%
FCF/Rev 3Y Avg-193,923.2%--0.3%26.4%12.7%6.5%

Valuation

ALTVKTXMDGLLLYAMGNPFEMedian
NameAltimmuneViking T.Madrigal.Eli LillyAmgen Pfizer  
Mkt Cap0.33.912.1824.0186.1152.582.3
P/S7,794.6-12.712.65.12.412.6
P/Op Inc-3.4-9.9-40.427.720.58.82.7
P/EBIT-3.7-9.9-45.627.715.915.05.6
P/E-3.6-10.9-42.139.924.119.68.0
P/CFO-4.7-14.0-64.049.018.713.04.1
Total Yield-24.0%-9.2%-2.4%3.2%6.9%11.5%0.4%
Dividend Yield0.0%0.0%0.0%0.7%2.8%6.4%0.3%
FCF Yield 3Y Avg-14.9%-4.3%-5.1%0.0%5.6%5.3%-2.1%
D/E0.10.00.00.10.30.40.1
Net D/E-0.7-0.2-0.10.00.20.3-0.0

Returns

ALTVKTXMDGLLLYAMGNPFEMedian
NameAltimmuneViking T.Madrigal.Eli LillyAmgen Pfizer  
1M Rtn-12.2%5.2%18.1%1.0%-1.1%0.2%0.6%
3M Rtn-34.6%2.5%6.4%-14.6%1.4%5.3%1.9%
6M Rtn-22.6%8.9%27.1%13.6%18.5%12.3%12.9%
12M Rtn-37.7%34.3%74.6%12.0%28.1%27.7%27.9%
3Y Rtn-47.8%61.4%74.2%144.1%55.8%-20.1%58.6%
1M Excs Rtn-19.6%-3.3%9.6%-7.4%-9.6%-8.3%-7.9%
3M Excs Rtn-38.0%-1.3%2.6%-18.4%-2.5%1.5%-1.9%
6M Excs Rtn-29.7%-4.6%14.2%8.1%9.6%6.4%7.3%
12M Excs Rtn-70.4%6.0%40.8%-25.0%-8.0%-7.9%-8.0%
3Y Excs Rtn-107.2%2.5%34.2%80.8%-18.8%-93.9%-8.1%

Financials

Segment Financials

Revenue by Segment
$ Mil2025202420232022
Developing novel peptide-based therapeutics for liver and cardiometabolic diseases0-048
Total0-048


Price Behavior

Price Behavior
Market Price$3.47 
Market Cap ($ Bil)0.4 
First Trading Date10/06/2005 
Distance from 52W High-55.0% 
   50 Days200 Days
DMA Price$3.74$4.09
DMA Trenddowndown
Distance from DMA-7.2%-15.1%
 3M1YR
Volatility81.9%92.0%
Downside Capture1.440.92
Upside Capture284.3198.75
Correlation (SPY)33.1%18.0%
ALT Betas & Captures as of 3/31/2026

 1M2M3M6M1Y3Y
Beta2.771.592.171.491.271.60
Up Beta8.902.492.572.141.351.58
Down Beta-0.460.89-0.040.180.651.50
Up Capture330%42%409%204%117%323%
Bmk +ve Days7162765139424
Stock +ve Days7112150107337
Down Capture352%246%246%172%144%111%
Bmk -ve Days12233358110323
Stock -ve Days13293871137400

[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with ALT
ALT-19.9%91.5%0.26-
Sector ETF (XLV)12.0%15.9%0.5221.4%
Equity (SPY)26.7%12.5%1.7717.7%
Gold (GLD)38.9%27.4%1.191.1%
Commodities (DBC)23.5%16.2%1.32-4.2%
Real Estate (VNQ)15.6%13.6%0.8218.7%
Bitcoin (BTCUSD)-12.8%42.6%-0.2112.3%

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Based On 5-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with ALT
ALT-21.3%94.3%0.21-
Sector ETF (XLV)5.6%14.6%0.2019.9%
Equity (SPY)10.5%17.1%0.4823.5%
Gold (GLD)21.5%17.8%0.993.6%
Commodities (DBC)10.7%18.8%0.471.1%
Real Estate (VNQ)3.6%18.8%0.0924.0%
Bitcoin (BTCUSD)3.8%56.4%0.2916.0%

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Based On 10-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with ALT
ALT-26.1%384.6%0.38-
Sector ETF (XLV)9.5%16.5%0.462.4%
Equity (SPY)13.8%17.9%0.663.9%
Gold (GLD)13.9%15.9%0.731.7%
Commodities (DBC)8.1%17.6%0.383.0%
Real Estate (VNQ)5.4%20.7%0.233.0%
Bitcoin (BTCUSD)68.1%66.9%1.072.2%

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Short Interest

Short Interest: As Of Date3312026
Short Interest: Shares Quantity29.2 Mil
Short Interest: % Change Since 315202610.4%
Average Daily Volume3.8 Mil
Days-to-Cover Short Interest7.6 days
Basic Shares Quantity105.8 Mil
Short % of Basic Shares27.6%

Earnings Returns History

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 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
3/5/2026-17.9%-11.0%-21.8%
11/6/20255.1%12.8%49.6%
8/12/20257.1%5.3%8.6%
5/13/2025-4.2%-8.5%8.8%
2/27/20258.1%-3.7%-6.2%
11/12/202429.1%-2.7%18.9%
8/8/202415.1%12.4%12.7%
3/27/20242.8%7.4%-16.8%
...
SUMMARY STATS   
# Positive171111
# Negative41010
Median Positive7.0%7.4%18.9%
Median Negative-10.2%-7.7%-16.9%
Max Positive29.1%33.7%157.7%
Max Negative-17.9%-26.6%-62.6%

SEC Filings

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Report DateFiling DateFiling
12/31/202503/06/202610-K
09/30/202511/06/202510-Q
06/30/202508/12/202510-Q
03/31/202505/13/202510-Q
12/31/202402/27/202510-K
09/30/202411/12/202410-Q
06/30/202408/08/202410-Q
03/31/202405/09/202410-Q
12/31/202303/27/202410-K
09/30/202311/07/202310-Q
06/30/202308/10/202310-Q
03/31/202305/11/202310-Q
12/31/202202/28/202310-K
09/30/202211/10/202210-Q
06/30/202208/11/202210-Q
03/31/202205/12/202210-Q