Aligos Therapeutics (ALGS)


Market Price (8/9/2026): $5.7 | Market Cap: $59.5 MilSector: Health Care | Industry: Biotechnology

Aligos Therapeutics (ALGS)


Market Price (8/9/2026): $5.7
Market Cap: $59.5 Mil
Sector: Health Care
Industry: Biotechnology

Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.

0

Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -46%

Strong revenue growth
Rev Chg LTMRevenue Change % Last Twelve Months (LTM) is 893%

Valuation becoming less expensive
P/S 6M Chg %Price/Sales change over 6 months. Declining P/S indicates valuation has become less expensive. is -89%

Megatrend and thematic drivers
Megatrends include Precision Medicine. Themes include Biopharmaceutical R&D, and Targeted Therapies.

Weak multi-year price returns
2Y Excs Rtn is -99%, 3Y Excs Rtn is -147%

Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -79 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -251%

Significant share based compensation
SBC/Rev LTMShare Based Compensation / Revenue (Sales), Last Twelve Months (LTM) is 18%

Not cash flow generative
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -299%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -300%

Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -135%

Key risks
ALGS key risks include [1] its heavy dependence on the success of unproven, Show more.

0 Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -46%
1 Strong revenue growth
Rev Chg LTMRevenue Change % Last Twelve Months (LTM) is 893%
2 Valuation becoming less expensive
P/S 6M Chg %Price/Sales change over 6 months. Declining P/S indicates valuation has become less expensive. is -89%
3 Megatrend and thematic drivers
Megatrends include Precision Medicine. Themes include Biopharmaceutical R&D, and Targeted Therapies.
4 Weak multi-year price returns
2Y Excs Rtn is -99%, 3Y Excs Rtn is -147%
5 Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -79 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -251%
6 Significant share based compensation
SBC/Rev LTMShare Based Compensation / Revenue (Sales), Last Twelve Months (LTM) is 18%
7 Not cash flow generative
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -299%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -300%
8 Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -135%
9 Key risks
ALGS key risks include [1] its heavy dependence on the success of unproven, Show more.

ALGS in ETFs

Weight = ALGS's share of each fund

DFAS0.00%
DFAC0.00%

Valuation & Metrics

Price Chart

Why The Stock Moved

Qualitative Assessment

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Updated on 8/6/2026

Aligos Therapeutics (ALGS) stock has lost about 5% since 4/30/2026 because of the following key factors:

1. Analyst Price Target Revision. On May 21, 2026, an analyst price target for Aligos Therapeutics was decreased by 15% to US$58.17, indicating a downward adjustment in future valuation expectations.

2. Extended Timeline for Key Clinical Trial Data. Despite the completion of enrollment in the Phase 2 B-SUPREME study for pevifoscorvir sodium for chronic HBV infection, topline safety and efficacy data are not anticipated until late fiscal Q3 2027. This extended waiting period for significant clinical trial results can contribute to investor uncertainty and a lack of immediate catalysts for the clinical-stage biotechnology company.

Show more
Updated on 8/6/2026

Aligos Therapeutics (ALGS) stock has lost about 5% since 4/30/2026 because of the following key factors:

1. Analyst Price Target Revision. On May 21, 2026, an analyst price target for Aligos Therapeutics was decreased by 15% to US$58.17, indicating a downward adjustment in future valuation expectations.

2. Extended Timeline for Key Clinical Trial Data. Despite the completion of enrollment in the Phase 2 B-SUPREME study for pevifoscorvir sodium for chronic HBV infection, topline safety and efficacy data are not anticipated until late fiscal Q3 2027. This extended waiting period for significant clinical trial results can contribute to investor uncertainty and a lack of immediate catalysts for the clinical-stage biotechnology company.

3. Cash Runway and Increased Research and Development Expenses. Aligos Therapeutics reported a decrease in cash, cash equivalents, and investments from $77.8 million as of December 31, 2025, to $54.9 million as of March 31, 2026 (the end of fiscal Q1 2026). While an exclusive license deal secured an upfront payment of $25 million in July 2026, extending the cash runway into fiscal Q4 2026, the company's research and development expenses significantly increased to $23.4 million in fiscal Q1 2026, compared to $14.5 million in fiscal Q1 2025, reflecting continued substantial cash utilization for clinical trials.

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Stock Movement Drivers

Fundamental Drivers

The -6.7% change in ALGS stock from 4/30/2026 to 8/8/2026 was primarily driven by a -93.5% change in the company's P/S Multiple.
(LTM values as of)43020268082026Change
Stock Price ($)5.995.59-6.7%
Change Contribution By: 
Total Revenues ($ Mil)2321341.8%
P/S Multiple28.51.8-93.5%
Shares Outstanding (Mil)1010-0.4%
Cumulative Contribution-6.7%

LTM = Last Twelve Months as of date shown

Market Drivers

4/30/2026 to 8/8/2026
ReturnCorrelation
ALGS-6.7% 
Market (SPY)7.6%25.0%
Sector (XLV)13.5%7.6%

Fundamental Drivers

The -30.7% change in ALGS stock from 1/31/2026 to 8/8/2026 was primarily driven by a -94.2% change in the company's P/S Multiple.
(LTM values as of)13120268082026Change
Stock Price ($)8.075.59-30.7%
Change Contribution By: 
Total Revenues ($ Mil)3321091.2%
P/S Multiple31.61.8-94.2%
Shares Outstanding (Mil)1010-0.6%
Cumulative Contribution-30.7%

LTM = Last Twelve Months as of date shown

Market Drivers

1/31/2026 to 8/8/2026
ReturnCorrelation
ALGS-30.7% 
Market (SPY)12.1%30.0%
Sector (XLV)7.5%15.4%

Fundamental Drivers

The -23.2% change in ALGS stock from 7/31/2025 to 8/8/2026 was primarily driven by a -90.1% change in the company's P/S Multiple.
(LTM values as of)73120258082026Change
Stock Price ($)7.285.59-23.2%
Change Contribution By: 
Total Revenues ($ Mil)332863.9%
P/S Multiple18.71.8-90.1%
Shares Outstanding (Mil)810-19.4%
Cumulative Contribution-23.2%

LTM = Last Twelve Months as of date shown

Market Drivers

7/31/2025 to 8/8/2026
ReturnCorrelation
ALGS-23.2% 
Market (SPY)23.4%20.4%
Sector (XLV)28.7%18.9%

Fundamental Drivers

The -74.9% change in ALGS stock from 7/31/2023 to 8/8/2026 was primarily driven by a -83.5% change in the company's Shares Outstanding (Mil).
(LTM values as of)73120238082026Change
Stock Price ($)22.255.59-74.9%
Change Contribution By: 
Total Revenues ($ Mil)1432124.2%
P/S Multiple2.71.8-31.9%
Shares Outstanding (Mil)210-83.5%
Cumulative Contribution-74.9%

LTM = Last Twelve Months as of date shown

Market Drivers

7/31/2023 to 8/8/2026
ReturnCorrelation
ALGS-74.9% 
Market (SPY)74.9%27.4%
Sector (XLV)29.3%16.4%

Return vs. Risk

Price Returns Compared

 202120222023202420252026Total [1]
Returns
ALGS Return-57%-92%-30%140%-77%-41%-99%
Peers Return-14%71%17%20%98%-2%298%
S&P 500 Return27%-19%24%23%16%13%105%

Monthly Win Rates [3]
ALGS Win Rate50%25%25%50%33%38% 
Peers Win Rate45%45%40%48%57%55% 
S&P 500 Win Rate75%42%67%75%67%50% 

Max Drawdowns [4]
ALGS Max Drawdown-67%-93%-73%-76%-91%-61% 
Peers Max Drawdown-41%-41%-41%-42%-35%-28% 
S&P 500 Max Drawdown-5%-25%-10%-8%-19%-9% 


[1] Cumulative total returns since the beginning of 2021
[2] Peers: MDGL, GILD, IONS, ARWR, VKTX.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 8/7/2026 (YTD)

How Low Can It Go

EventALGSS&P 500
2024 Yen Carry Trade Unwind
  % Loss-12.3%-7.8%
  % Gain to Breakeven14.0%8.5%
  Time to Breakeven1 days18 days
Summer-Fall 2023 Five Percent Yield Shock
  % Loss-39.8%-9.5%
  % Gain to Breakeven66.0%10.5%
  Time to Breakeven78 days24 days
2023 SVB Regional Banking Crisis
  % Loss-42.5%-6.7%
  % Gain to Breakeven73.9%7.1%
  Time to Breakeven629 days31 days

Compare to MDGL, GILD, IONS, ARWR, VKTX

In The Past

Aligos Therapeutics's stock fell -12.3% during the 2024 Yen Carry Trade Unwind. Such a loss loss requires a 14.0% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

EventALGSS&P 500
Summer-Fall 2023 Five Percent Yield Shock
  % Loss-39.8%-9.5%
  % Gain to Breakeven66.0%10.5%
  Time to Breakeven78 days24 days
2023 SVB Regional Banking Crisis
  % Loss-42.5%-6.7%
  % Gain to Breakeven73.9%7.1%
  Time to Breakeven629 days31 days

Compare to MDGL, GILD, IONS, ARWR, VKTX

In The Past

Aligos Therapeutics's stock fell -12.3% during the 2024 Yen Carry Trade Unwind. Such a loss loss requires a 14.0% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

About Aligos Therapeutics (ALGS)

Aligos Therapeutics, Inc. (ALGS) is a clinical-stage biopharmaceutical company focused on developing novel treatments for significant unmet medical needs within viral and liver diseases. Headquartered in South San Francisco, California, the company's research and development efforts are primarily directed toward creating innovative therapies for chronic conditions such as chronic hepatitis B (CHB) and non-alcoholic steatohepatitis (NASH).

The company's pipeline includes several promising drug candidates targeting chronic hepatitis B, with lead programs like ALG-010133, an s-antigen transport-inhibiting oligonucleotide polymer currently in Phase Ib clinical trials, and ALG-000184, a capsid assembly modulator in Phase I. Aligos is also developing other approaches for CHB, including ALG-020572 (an antisense oligonucleotide) and siRNA candidates. For liver diseases, Aligos is advancing ALG-055009, a small molecule THR-ß agonist, which is in Phase 1a/1b clinical trials for the treatment of non-alcoholic steatohepatitis (NASH).

Aligos Therapeutics aims to serve patients globally who suffer from these chronic viral and liver diseases, specifically CHB and NASH. The company's business model incorporates both internal drug discovery and strategic collaborations, demonstrated through agreements with partners like Luxna Biotech, Emory University, and Merck, to leverage diverse technologies and expertise in the development and potential commercialization of its therapeutic programs.

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Here are 1-2 brief analogies for Aligos Therapeutics:

  • An early-stage Gilead Sciences, specializing in developing new treatments for chronic hepatitis B and fatty liver disease.

  • A biotech startup focused on discovering breakthrough drugs for liver and viral diseases, much like a young Vertex Pharmaceuticals before its major successes in specific disease areas.

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  • ALG-010133: An oligonucleotide polymer designed to inhibit s-antigen transport for chronic hepatitis B.
  • ALG-000184: A capsid assembly modulator in development for chronic hepatitis B.
  • ALG-020572: An antisense oligonucleotide aimed at preventing HBsAg translation and secretion.
  • ALG-055009: A small molecule THR-ß agonist targeting non-alcoholic steatohepatitis (NASH).
  • ALG-125755: An siRNA drug candidate developed to inhibit HBsAg release.
  • ALG-125097 and ALG-125819: Drug candidates designed to potently inhibit HBsAg release from HBV-infected cells.

AI Analysis | Feedback

Aligos Therapeutics, Inc. (ALGS) is a clinical-stage biopharmaceutical company focused on developing novel therapeutics. As such, it does not currently have commercial products on the market sold to individuals or traditional customers.

Instead, its major "customers" or revenue sources come from strategic collaborations and licensing agreements with other companies and institutions that provide funding, research support, and rights for future commercialization of its drug candidates and technologies. Based on the provided description, these include:

  • Luxna Biotech Co., Ltd. (Private company)
  • Emory University (Academic institution)
  • Katholieke Universiteit Leuven (Academic institution)
  • Merck (Public company, symbol: MRK) - *Correction: Merck & Co., Inc. symbol is MRK.*

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Lawrence M. Blatt, Ph. D., M.B.A. Chief Executive Officer Dr. Blatt co-founded Aligos Therapeutics and has served as its Chief Executive Officer and a member of the board of directors since February 2018. He is a serial biotech entrepreneur who co-founded Alios BioPharma, Inc., serving as its Chief Executive Officer, President, and Director from January 2009 until its acquisition by Johnson & Johnson in November 2014 for $1.75 billion. Prior to Alios, he was Chief Scientific Officer of InterMune, Inc., which was acquired by Roche in 2014. He also served as the Global Head of Infectious Diseases and Vaccines at Janssen Pharmaceutical Companies of Johnson & Johnson from November 2014 to February 2018. Dr. Blatt also co-founded and is Chairman of the Board of Directors for Alveo Diagnostics. He is the recipient of the Ernst & Young Entrepreneur of the Year Award in the life science category. Lesley Ann Calhoun Executive Vice President, Chief Operating Officer, and Chief Financial Officer Ms. Calhoun has served as Aligos' Executive Vice President, Chief Financial Officer since June 2020. She is an experienced finance executive with 17 years in the biopharma industry, with an earlier career in U.S. and multinational technology companies and public accounting. Prior to joining Aligos, Ms. Calhoun was Senior Vice President of Finance & Administration and Chief Accounting Officer at Global Blood Therapeutics (GBT). At GBT, she was responsible for the finance, accounting, and administrative functions, supporting the company's transition from a clinical stage to a publicly traded, commercial environment, and was involved in the successful regulatory approval and commercial launch of Oxbryta®. She also served as Vice President of Finance at Hyperion Therapeutics Inc., where she played a key role in building the finance infrastructure that led to the successful commercialization of RAVICTI®. Ms. Calhoun has served as a Director of Tango Therapeutics, Inc., a publicly traded biotechnology company, since March 2021, and is the Chair of the Audit Committee and a member of the Nominating and Corporate Governance Committee. Sushmita M. Chanda, Ph. D. Executive Vice President, Chief Development Officer Dr. Chanda serves as Aligos' Executive Vice President and Chief Development Officer. Before joining Aligos, she was Vice President, Preclinical Development at Alios BioPharma, Inc., from February 2010 to July 2018, until its acquisition by Janssen Pharmaceutical Companies of Johnson & Johnson. From 2000 to 2010, Dr. Chanda held various roles of increasing responsibilities at F. Hoffman-La Roche Ltd, including Senior Director and Head of Nonclinical Safety. James Hassard, MBA Executive Vice President, Chief Commercial Officer Mr. Hassard was appointed Executive Vice President, Chief Commercial Officer, effective January 13, 2026. In this role, he will lead and build the company's global commercial capabilities and serve as a member of Aligos' Senior Leadership Team. He is a seasoned executive with extensive experience building commercial organizations across multiple therapeutic areas. Prior to Aligos, Mr. Hassard was Chief Commercial Officer at Crinetics Pharmaceuticals and Arrowhead Pharmaceuticals, where he developed commercial capabilities and launch strategies for over four rare disease programs. His career also includes positions of increasing responsibility at Coherus Oncology, Amgen, and Merck, with global experience in the U.S., Canada, and Europe, where he launched pharmaceutical products in therapeutic areas such as hepatitis, oncology, and nephrology. Hardean Achneck, M.D. Chief Medical Officer Dr. Achneck has been appointed as Aligos' Chief Medical Officer, effective immediately. He spearheads the company's global clinical development initiatives and is a member of the Senior Leadership Team. Dr. Achneck possesses extensive experience in clinical development across various therapeutic areas, including hepatology and infectious diseases. Before joining Aligos, he was Vice President of Clinical Development at Dicerna Therapeutics, which was acquired by Novo Nordisk in 2021. He continued to lead efforts within the Novo Nordisk Dicerna Transformational Research Unit, focusing on liver-targeted therapies like xalnesiran for chronic hepatitis B. Prior to his biopharmaceutical industry career, Dr. Achneck was an Assistant Professor of Surgery and Pathology at Duke University School of Medicine, and also held a joint appointment as Assistant Professor of Cardiovascular & Metabolic Disorders at Duke-National University of Singapore.

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The key risks to Aligos Therapeutics (ALGS) are primarily related to its financial viability, the inherent challenges of drug development, and intense competition in its target therapeutic areas.

  1. Financial Health and Going Concern Risk: Aligos Therapeutics faces significant financial challenges, with reported negative operating and net margins and a low cash runway. Management has expressed substantial doubt about the company's ability to continue as a going concern without securing additional financing, as existing funds are expected to last only into the third quarter of 2026. This indicates a critical need for further capital to sustain operations and ongoing drug development programs.

  2. Clinical Development and Regulatory Approval Risk: As a clinical-stage biopharmaceutical company, Aligos' future success is highly dependent on the successful outcome of its drug candidates in clinical trials and their ability to gain regulatory approval. The company's lead candidates, such as ALG-010133, ALG-000184 (pevifoscorvir sodium), ALG-020572, and ALG-055009, are in early to mid-stage clinical trials (Phase Ib, Phase I, Phase 1a/1b, Phase 2), and there is no guarantee that they will demonstrate sufficient efficacy or safety, or ultimately receive marketing authorization.

  3. Competition: Aligos Therapeutics operates in highly competitive therapeutic areas, including chronic hepatitis B (CHB) and non-alcoholic steatohepatitis (NASH). Numerous other pharmaceutical and biotechnology companies are actively developing or marketing competing therapies for these conditions. Aligos' drug candidates, particularly ALG-055009 for NASH, are positioned in a "competitively challenged" landscape. The company's ability to differentiate its products and secure market share against existing and emerging treatments is a significant risk.

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Aligos Therapeutics (ALGS) focuses on developing novel therapeutics for viral and liver diseases, with lead drug candidates targeting Chronic Hepatitis B (CHB) and Non-alcoholic Steatohepatitis (NASH). The addressable markets for these main products are substantial globally and in key regions.

Chronic Hepatitis B (CHB)

  • The global chronic hepatitis B market was valued at approximately USD 2,709.4 million in 2023 and is projected to reach USD 3,379.3 million by 2034.
  • The Chronic Hepatitis B therapeutics market across the seven major markets (7MM), which include the U.S., EU4 (Germany, France, Italy, and Spain), the United Kingdom, and Japan, is forecast to grow from USD 1.5 billion in 2024 to USD 3.2 billion by 2034.
  • In 2024, the U.S. alone represented the largest market for CHB within the 7MM, with sales of USD 710.11 million. The U.S. Hepatitis B Treatment Market is projected to grow from USD 1.00 billion in 2025 to USD 1.54 billion by 2033.

Non-alcoholic Steatohepatitis (NASH)

  • The global NASH drugs market was valued at USD 5.7 billion in 2024, is projected to reach USD 7.7 billion in 2025, and is expected to grow significantly to USD 78.2 billion by 2035.
  • Another estimate places the global non-alcoholic steatohepatitis treatment market size at USD 7.72 billion in 2024, with a projection to reach USD 33.80 billion by 2030. Similarly, the global non-alcoholic steatohepatitis treatment market size was calculated at USD 7.75 billion in 2024 and is projected to reach around USD 92.5 billion by 2034.
  • North America dominated the global non-alcoholic steatohepatitis treatment market, accounting for a 79.12% share in 2024. The U.S. non-alcoholic steatohepatitis treatment market was valued at USD 4.56 billion in 2024 and is expected to reach USD 32.55 billion by 2032. In 2023, the U.S. NASH market was approximately USD 1,519 million.

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Here are 3-5 expected drivers of future revenue growth for Aligos Therapeutics (ALGS) over the next 2-3 years:
  1. Milestone Payments from Existing Collaboration Agreements: Aligos Therapeutics stands to generate revenue through milestone payments from its existing license and collaboration agreements. Specifically, the company has an agreement with Merck for the discovery and development of oligonucleotide therapies for non-alcoholic steatohepatitis (NASH) and up to one additional cardiometabolic/fibrosis target. Under this collaboration, Aligos is eligible for development and commercialization milestones that could reach up to $458 million to $460 million, in addition to tiered royalties on net sales. Furthermore, its partnership with Xiamen Amoytop Biotech Co. for ALG-170675, a dual-mechanism antisense oligonucleotide for chronic hepatitis B (CHB), involves Amoytop funding development costs in China and advancing the candidate into IND-enabling studies, which could trigger additional milestone payments to Aligos.
  2. New Partnership for ALG-055009 (Obesity/MASH): Aligos is actively pursuing a partnership for its small molecule THR-β agonist, ALG-055009, which is being developed for obesity and metabolic dysfunction-associated steatohepatitis (MASH). Recent preclinical data demonstrating significant synergistic weight loss when ALG-055009 is combined with incretin therapies (like GLP-1s) has substantially enhanced its commercial appeal beyond MASH, potentially accelerating discussions for a lucrative out-licensing deal. Such a new collaboration could provide Aligos with upfront payments, development milestones, and future royalties, contributing significantly to its revenue growth. The company has expressed enthusiasm and is in "continued discussions with potential partners for obesity and MASH" for ALG-055009.
  3. Advancement and Potential Monetization of Chronic Hepatitis B (CHB) Pipeline: The progression of Aligos' lead CHB drug candidate, pevifoscorvir sodium (ALG-000184), is a crucial driver. The Phase 2 B-SUPREME study for pevifoscorvir sodium has completed planned enrollment for the HBeAg- cohort and is continuing enrollment for the HBeAg+ cohort, with interim analyses expected in the first and second half of 2026, and topline data anticipated in 2027. Positive clinical trial readouts are essential to attracting new partners or expanding existing collaborations for the CHB program, which could lead to further milestone payments or new licensing agreements. The company believes pevifoscorvir sodium may impact key aspects of HBV disease pathogenesis (replication, integration, and viral reservoir maintenance).

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Share Issuance

  • Aligos Therapeutics completed a public offering in June 2021, issuing 4,400,000 shares of common stock at $19.00 per share, generating gross proceeds of approximately $83.6 million.
  • In March 2026, a registration statement was filed for the issuance of 519,783 shares of common stock under the 2020 Incentive Award Plan and 61,782 shares under the 2020 Employee Stock Purchase Plan.
  • In January 2026, the company granted non-qualified stock options for an aggregate of 81,100 shares to newly hired employees as inducement grants.

Inbound Investments

  • Aligos Therapeutics has raised a total of $225 million across four funding rounds.
  • Cash, cash equivalents, and investments totaled $77.8 million as of December 31, 2025, which is expected to provide sufficient funding into the third quarter of 2026.

Capital Expenditures

  • In the 12 months leading up to March 2026, capital expenditures amounted to -$437,000.
  • The company invested $7K in capital expenditures in Q1 2023, primarily to fund long-term assets and infrastructure.
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Better Bets vs. Aligos Therapeutics (ALGS)

Recent Active Movers

Peer Comparisons

Peers to compare with:

Financials

ALGSMDGLGILDIONSARWRVKTXMedian
NameAligos T.Madrigal.Gilead S.Ionis Ph.Arrowhea.Viking T. 
Mkt Price5.59510.04133.2156.5687.6534.2672.11
Mkt Cap0.114.9165.69.412.64.011.0
Rev LTM321,28430,4568746690772
Op Inc LTM-79-32311,716-594-226-560-275
FCF LTM-95-20612,943-568-75-418-150
FCF 3Y Avg-85-3239,736-410-208-214-211
CFO LTM-94-19813,552-496-59-418-146
CFO 3Y Avg-85-31810,296-358-130-214-172

Growth & Margins

ALGSMDGLGILDIONSARWRVKTXMedian
NameAligos T.Madrigal.Gilead S.Ionis Ph.Arrowhea.Viking T. 
Rev Chg LTM893.0%149.0%5.5%-7.4%16.8%-16.8%
Rev Chg 3Y Avg259.7%-3.6%12.5%913.6%-136.1%
Rev Chg Q2,778.5%71.2%10.2%-40.7%171.0%-71.2%
QoQ Delta Rev Chg LTM569.9%13.4%2.4%-17.4%7.6%-7.6%
Op Inc Chg LTM-0.6%-4.1%7.6%-123.0%-109.7%-163.1%-56.9%
Op Inc Chg 3Y Avg1.7%-7.7%-0.8%-24.5%-77.5%-96.1%-16.1%
Op Mgn LTM-250.6%-25.1%38.5%-68.0%-33.8%--33.8%
Op Mgn 3Y Avg-1,299.3%-1,236.0%37.0%-47.0%-945.9%--945.9%
QoQ Delta Op Mgn LTM1,782.8%2.6%-1.6%-34.7%1.9%-1.9%
CFO/Rev LTM-298.8%-15.4%44.5%-56.8%-8.8%--15.4%
CFO/Rev 3Y Avg-1,243.0%-1,047.4%35.2%-41.2%-598.1%--598.1%
FCF/Rev LTM-299.9%-16.0%42.5%-64.9%-11.2%--16.0%
FCF/Rev 3Y Avg-1,245.9%-1,063.3%33.3%-47.1%-908.4%--908.4%

Valuation

ALGSMDGLGILDIONSARWRVKTXMedian
NameAligos T.Madrigal.Gilead S.Ionis Ph.Arrowhea.Viking T. 
Mkt Cap0.114.9165.69.412.64.011.0
P/S1.811.65.410.718.8-10.7
P/Op Inc-0.7-46.114.1-15.7-55.5-7.1-11.4
P/EBIT-0.7-50.6-173.0-19.5-78.8-7.1-35.1
P/E-0.8-45.7-51.1-16.6-39.3-7.4-27.9
P/CFO-0.6-75.212.2-18.8-212.8-9.5-14.2
Total Yield-130.3%-2.2%0.5%-6.0%-2.5%-13.4%-4.3%
Dividend Yield0.0%0.0%2.5%0.0%0.0%0.0%0.0%
FCF Yield 3Y Avg-137.8%-4.2%7.7%-4.8%-6.0%-5.2%-5.0%
D/E0.10.00.20.20.10.00.1
Net D/E-0.5-0.00.1-0.0-0.0-0.1-0.0

Returns

ALGSMDGLGILDIONSARWRVKTXMedian
NameAligos T.Madrigal.Gilead S.Ionis Ph.Arrowhea.Viking T. 
1M Rtn-17.4%-8.9%-1.2%-12.0%4.3%-16.7%-10.5%
3M Rtn-13.2%0.0%2.1%-25.3%20.6%9.4%1.0%
6M Rtn-23.6%6.8%-11.6%-34.6%35.8%20.5%-2.4%
12M Rtn-27.3%47.5%14.5%35.8%433.8%-9.6%25.1%
3Y Rtn-77.0%202.3%83.4%41.4%202.1%134.8%109.1%
1M Excs Rtn-20.3%-11.8%-4.0%-14.8%1.5%-19.6%-13.3%
3M Excs Rtn-13.0%-10.4%-5.7%-31.3%6.7%2.8%-8.0%
6M Excs Rtn-28.0%-4.0%-23.8%-46.4%21.5%16.2%-13.9%
12M Excs Rtn-52.7%28.6%1.7%16.7%415.1%-14.8%9.2%
3Y Excs Rtn-147.0%85.1%22.4%-31.9%94.0%74.4%48.4%

Comparison Analyses

null

Financials

Segment Financials

Revenue by Segment
$ Mil20252024202320222021
Discovering and developing drug candidates in both liver and viral diseases2416144
Total2416144


Net Income by Segment
$ Mil202520242023
Discovering and developing drug candidates in both liver and viral diseases-24-131-88
Total-24-131-88


Assets by Segment
$ Mil20202019
Discovering and developing drug candidates in both liver and viral diseases265147
Total265147


Price Behavior

Price Behavior
Market Price$5.59 
Market Cap ($ Bil)0.1 
First Trading Date10/16/2020 
Distance from 52W High-58.0% 
   50 Days200 Days
DMA Price$5.38$7.31
DMA Trenddowndown
Distance from DMA3.8%-23.6%
 3M1YR
Volatility84.2%82.9%
Downside Capture114.7072.43
Upside Capture30.4519.00
Correlation (SPY)26.2%20.1%
ALGS Betas & Captures as of 7/31/2026

 1M2M3M6M1Y3Y
Beta1.240.611.351.621.271.86
Up Beta4.981.781.892.802.731.73
Down Beta1.131.792.022.351.972.42
Up Capture-198%-102%5%14%5%138%
Bmk +ve Days11223567138427
Stock +ve Days8172859127353
Down Capture249%77%176%157%100%111%
Bmk -ve Days11212859114326
Stock -ve Days12233264122383

[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with ALGS
ALGS-30.6%82.8%-0.08-
Sector ETF (XLV)28.7%15.5%1.4218.5%
Equity (SPY)23.3%12.8%1.3620.1%
Gold (GLD)28.5%28.4%0.878.1%
Commodities (DBC)32.9%19.8%1.32-4.9%
Real Estate (VNQ)14.2%13.8%0.728.5%
Bitcoin (BTCUSD)-43.7%43.0%-1.2119.5%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 5-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with ALGS
ALGS-56.9%99.6%-0.37-
Sector ETF (XLV)6.2%15.0%0.2315.5%
Equity (SPY)13.5%17.2%0.6125.0%
Gold (GLD)18.6%18.6%0.811.4%
Commodities (DBC)8.2%19.6%0.314.0%
Real Estate (VNQ)2.3%18.9%0.0214.4%
Bitcoin (BTCUSD)9.0%53.0%0.3619.9%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 10-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with ALGS
ALGS-34.4%99.8%-0.26-
Sector ETF (XLV)10.1%16.6%0.4915.1%
Equity (SPY)15.4%17.9%0.7323.7%
Gold (GLD)12.1%16.2%0.611.0%
Commodities (DBC)7.4%18.0%0.333.9%
Real Estate (VNQ)4.8%20.7%0.2014.0%
Bitcoin (BTCUSD)58.4%66.2%0.9817.3%

Smart multi-asset allocation framework can stack odds in your favor. Learn How

Short Interest

Short Interest: As Of Date7152026
Short Interest: Shares Quantity0.5 Mil
Short Interest: % Change Since 6302026-4.0%
Average Daily Volume0.5 Mil
Days-to-Cover Short Interest1.0 days
Basic Shares Quantity10.4 Mil
Short % of Basic Shares5.0%

Earnings Returns History

Updated 8/9/2026
Expand for More
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
8/6/202616.2%  
5/7/20266.8%10.9%-17.7%
3/5/2026-2.9%10.3%16.2%
11/6/2025-3.1%-11.9%47.1%
8/6/20251.1%-4.9%41.0%
5/6/2025-9.3%12.5%24.6%
3/10/2025-19.6%-11.6%-61.0%
11/6/20246.1%109.4%206.6%
...
SUMMARY STATS   
# Positive111111
# Negative121111
Median Positive5.7%10.3%21.8%
Median Negative-3.0%-11.6%-17.7%
Max Positive21.9%109.4%206.6%
Max Negative-19.6%-17.6%-61.0%
Collapse to Preview
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
8/6/202616.2%  
5/7/20266.8%10.9%-17.7%
3/5/2026-2.9%10.3%16.2%
11/6/2025-3.1%-11.9%47.1%
8/6/20251.1%-4.9%41.0%
5/6/2025-9.3%12.5%24.6%
3/10/2025-19.6%-11.6%-61.0%
11/6/20246.1%109.4%206.6%
8/6/202421.9%20.6%6.8%
5/7/2024-0.9%-12.5%-26.8%
3/12/20240.0%7.1%21.8%
11/2/20231.4%2.7%-9.3%
8/3/2023-0.6%9.0%-2.2%
5/4/2023-8.8%-17.6%-16.2%
3/9/2023-2.9%-2.9%-34.4%
11/2/2022-1.9%-16.5%-10.3%
8/4/20227.9%0.7%-12.2%
5/4/2022-11.3%-12.1%5.6%
3/10/20225.7%12.2%-26.5%
11/4/20215.5%5.0%-20.5%
8/5/2021-2.5%-3.1%5.1%
5/10/20215.6%-10.1%19.4%
3/23/2021-9.8%-1.9%22.3%
SUMMARY STATS   
# Positive111111
# Negative121111
Median Positive5.7%10.3%21.8%
Median Negative-3.0%-11.6%-17.7%
Max Positive21.9%109.4%206.6%
Max Negative-19.6%-17.6%-61.0%

SEC Filings

Expand for More
Report DateFiling DateFiling
06/30/202608/06/202610-Q
03/31/202605/07/202610-Q
12/31/202503/05/202610-K
09/30/202511/06/202510-Q
06/30/202508/06/202510-Q
03/31/202505/06/202510-Q
12/31/202403/10/202510-K
09/30/202411/06/202410-Q
06/30/202408/06/202410-Q
03/31/202405/07/202410-Q
12/31/202303/12/202410-K
09/30/202311/02/202310-Q
06/30/202308/03/202310-Q
03/31/202305/04/202310-Q
12/31/202203/09/202310-K
09/30/202211/02/202210-Q
Collapse to Preview
Report DateFiling DateFiling
06/30/202608/06/202610-Q
03/31/202605/07/202610-Q
12/31/202503/05/202610-K
09/30/202511/06/202510-Q
06/30/202508/06/202510-Q
03/31/202505/06/202510-Q
12/31/202403/10/202510-K
09/30/202411/06/202410-Q
06/30/202408/06/202410-Q
03/31/202405/07/202410-Q
12/31/202303/12/202410-K
09/30/202311/02/202310-Q
06/30/202308/03/202310-Q
03/31/202305/04/202310-Q
12/31/202203/09/202310-K
09/30/202211/02/202210-Q
06/30/202208/04/202210-Q
03/31/202205/04/202210-Q
12/31/202103/10/202210-K
09/30/202111/04/202110-Q
06/30/202108/05/202110-Q
03/31/202105/10/202110-Q
12/31/202003/23/202110-K
09/30/202011/25/202010-Q
06/30/202010/19/2020424B4

Recent Forward Guidance

Updated 8/7/2026

Latest: Q2 2026 Earnings Reported 8/6/2026

Forward GuidanceGuidance Change
MetricLowMidHigh% Chg% DeltaChangePrior
Q3 2026 Milestone Payment 3.00 Mil    

Prior: Q3 2025 Earnings Reported 11/6/2025

Forward GuidanceGuidance Change
MetricLowMidHigh% Chg% DeltaChangePrior
Q3 2026 Cash Runway      
Core Cache Last Updated: 8/8/2026