Tearsheet

Adaptive Biotechnologies (ADPT)


Market Price (6/26/2026): $20.0 | Market Cap: $3.1 BilSector: Health Care | Industry: Life Sciences Tools & Services

Adaptive Biotechnologies (ADPT)


Market Price (6/26/2026): $20.0
Market Cap: $3.1 Bil
Sector: Health Care
Industry: Life Sciences Tools & Services

Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.

0

Strong revenue growth
Rev Chg LTMRevenue Change % Last Twelve Months (LTM) is 56%

Megatrend and thematic drivers
Megatrends include Biotechnology & Genomics, and Precision Medicine. Themes include Advanced Diagnostics, Personalized Diagnostics, Show more.

Trading close to highs
Dist 52W High is -1.0%, Dist 3Y High is -1.0%

Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -47 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -16%

Significant share based compensation
SBC/Rev LTMShare Based Compensation / Revenue (Sales), Last Twelve Months (LTM) is 17%

Not cash flow generative
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -9.2%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -10.0%

Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -5.8%

Key risks
ADPT key risks include [1] a history of financial losses and an unproven path to profitability, Show more.

0 Strong revenue growth
Rev Chg LTMRevenue Change % Last Twelve Months (LTM) is 56%
1 Megatrend and thematic drivers
Megatrends include Biotechnology & Genomics, and Precision Medicine. Themes include Advanced Diagnostics, Personalized Diagnostics, Show more.
2 Trading close to highs
Dist 52W High is -1.0%, Dist 3Y High is -1.0%
3 Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -47 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -16%
4 Significant share based compensation
SBC/Rev LTMShare Based Compensation / Revenue (Sales), Last Twelve Months (LTM) is 17%
5 Not cash flow generative
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -9.2%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -10.0%
6 Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -5.8%
7 Key risks
ADPT key risks include [1] a history of financial losses and an unproven path to profitability, Show more.

ADPT in ETFs

Weight = ADPT's share of each fund

VTI0.00%
ITOT0.00%
IWM0.07%
VB0.01%
IBB0.23%
IWO0.14%
VTWO0.06%
ESML0.06%
+7 more covered ETFs

Valuation & Metrics

Price Chart

Why The Stock Moved

Qualitative Assessment

AI Analysis | Feedback

Updated on 6/25/2026

Adaptive Biotechnologies (ADPT) stock has gained about 25% since 2/28/2026 because of the following key factors:

1. Strong Fiscal Q1 2026 Financial Performance Exceeded Expectations.

Adaptive Biotechnologies reported robust results for fiscal Q1 2026, which ended March 31, 2026, on May 5, 2026. The company posted a basic EPS loss of -$0.13, outperforming analyst consensus estimates of -$0.16 by $0.03. Additionally, total revenue reached $70.9 million, a 35.1% increase year-over-year, surpassing the consensus estimate of $61.03 million.

2. Raised Full-Year 2026 Revenue Guidance for Minimal Residual Disease (MRD) Business.

Following the strong first quarter, Adaptive Biotechnologies raised its full-year 2026 revenue guidance for its core Minimal Residual Disease (MRD) business. The new guidance range was updated to $260 million to $270 million, an increase from the previous range of $255 million to $265 million. This revised outlook indicates management's increased confidence in sustained growth within its primary revenue-generating segment.

Show more
Updated on 6/25/2026

Adaptive Biotechnologies (ADPT) stock has gained about 25% since 2/28/2026 because of the following key factors:

1. Strong Fiscal Q1 2026 Financial Performance Exceeded Expectations.

Adaptive Biotechnologies reported robust results for fiscal Q1 2026, which ended March 31, 2026, on May 5, 2026. The company posted a basic EPS loss of -$0.13, outperforming analyst consensus estimates of -$0.16 by $0.03. Additionally, total revenue reached $70.9 million, a 35.1% increase year-over-year, surpassing the consensus estimate of $61.03 million.

2. Raised Full-Year 2026 Revenue Guidance for Minimal Residual Disease (MRD) Business.

Following the strong first quarter, Adaptive Biotechnologies raised its full-year 2026 revenue guidance for its core Minimal Residual Disease (MRD) business. The new guidance range was updated to $260 million to $270 million, an increase from the previous range of $255 million to $265 million. This revised outlook indicates management's increased confidence in sustained growth within its primary revenue-generating segment.

3. Significant Growth in MRD Segment and clonoSEQ Test Volume.

The growth in fiscal Q1 2026 was primarily propelled by the MRD business, which contributed 95% of total revenue and experienced a substantial 53% year-over-year increase, reaching $67.1 million. The volume of clonoSEQ tests delivered also saw significant growth, rising 41% year-over-year to 32,595 tests. This strong operational performance in its key product reinforces market leadership.

4. Positive Analyst Sentiment and Reiterated Buy Ratings.

Wall Street analysts maintained a bullish stance on Adaptive Biotechnologies during this period. Several firms reiterated "Buy" or "Overweight" ratings, with a consensus price target averaging around $20.00 to $20.33, and a high target of $22.00 from BTIG as of June 17, 2026. The overall analyst consensus rating for ADPT is "Moderate Buy" or "Strong Buy", suggesting continued confidence in the company's prospects.

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Stock Movement Drivers

Fundamental Drivers

The 26.4% change in ADPT stock from 2/28/2026 to 6/25/2026 was primarily driven by a 20.4% change in the company's P/S Multiple.
(LTM values as of)22820266252026Change
Stock Price ($)16.0220.2526.4%
Change Contribution By: 
Total Revenues ($ Mil)2772956.7%
P/S Multiple8.910.720.4%
Shares Outstanding (Mil)153156-1.5%
Cumulative Contribution26.4%

LTM = Last Twelve Months as of date shown

Market Drivers

2/28/2026 to 6/25/2026
ReturnCorrelation
ADPT26.4% 
Market (SPY)7.3%46.0%
Sector (XLV)-2.5%56.0%

Fundamental Drivers

The 3.0% change in ADPT stock from 11/30/2025 to 6/25/2026 was primarily driven by a 16.9% change in the company's Total Revenues ($ Mil).
(LTM values as of)113020256252026Change
Stock Price ($)19.6620.253.0%
Change Contribution By: 
Total Revenues ($ Mil)25329516.9%
P/S Multiple11.910.7-10.1%
Shares Outstanding (Mil)152156-2.0%
Cumulative Contribution3.0%

LTM = Last Twelve Months as of date shown

Market Drivers

11/30/2025 to 6/25/2026
ReturnCorrelation
ADPT3.0% 
Market (SPY)8.1%32.2%
Sector (XLV)-0.5%37.9%

Fundamental Drivers

The 112.7% change in ADPT stock from 5/31/2025 to 6/25/2026 was primarily driven by a 55.9% change in the company's Total Revenues ($ Mil).
(LTM values as of)53120256252026Change
Stock Price ($)9.5220.25112.7%
Change Contribution By: 
Total Revenues ($ Mil)19029555.9%
P/S Multiple7.510.742.3%
Shares Outstanding (Mil)149156-4.1%
Cumulative Contribution112.7%

LTM = Last Twelve Months as of date shown

Market Drivers

5/31/2025 to 6/25/2026
ReturnCorrelation
ADPT112.7% 
Market (SPY)26.0%33.2%
Sector (XLV)19.4%31.1%

Fundamental Drivers

The 190.9% change in ADPT stock from 5/31/2023 to 6/25/2026 was primarily driven by a 96.7% change in the company's P/S Multiple.
(LTM values as of)53120236252026Change
Stock Price ($)6.9620.25190.9%
Change Contribution By: 
Total Revenues ($ Mil)18429560.3%
P/S Multiple5.410.796.7%
Shares Outstanding (Mil)144156-7.7%
Cumulative Contribution190.9%

LTM = Last Twelve Months as of date shown

Market Drivers

5/31/2023 to 6/25/2026
ReturnCorrelation
ADPT190.9% 
Market (SPY)82.6%34.9%
Sector (XLV)28.0%29.7%

Return vs. Risk

Price Returns Compared

 202120222023202420252026Total [1]
Returns
ADPT Return-53%-73%-36%22%171%19%-67%
Peers Return-3%-52%13%19%58%36%33%
S&P 500 Return27%-19%24%23%16%7%96%

Monthly Win Rates [3]
ADPT Win Rate33%33%33%67%67%67% 
Peers Win Rate55%32%48%50%57%63% 
S&P 500 Win Rate75%42%67%75%67%50% 

Max Drawdowns [4]
ADPT Max Drawdown-63%-78%-66%-52%-28%-35% 
Peers Max Drawdown-33%-63%-44%-36%-36%-31% 
S&P 500 Max Drawdown-5%-25%-10%-8%-19%-9% 


[1] Cumulative total returns since the beginning of 2021
[2] Peers: NTRA, GH, ILMN, TXG, QGEN.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 6/25/2026 (YTD)

How Low Can It Go

EventADPTS&P 500
2025 US Tariff Shock
  % Loss-20.3%-18.8%
  % Gain to Breakeven25.5%23.1%
  Time to Breakeven11 days79 days
Summer-Fall 2023 Five Percent Yield Shock
  % Loss-56.0%-9.5%
  % Gain to Breakeven127.2%10.5%
  Time to Breakeven436 days24 days
2023 SVB Regional Banking Crisis
  % Loss-30.5%-6.7%
  % Gain to Breakeven43.9%7.1%
  Time to Breakeven665 days31 days
2020 COVID-19 Crash
  % Loss-49.4%-33.7%
  % Gain to Breakeven97.6%50.9%
  Time to Breakeven51 days140 days

Compare to NTRA, GH, ILMN, TXG, QGEN

In The Past

Adaptive Biotechnologies's stock fell -20.3% during the 2025 US Tariff Shock. Such a loss loss requires a 25.5% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

EventADPTS&P 500
2025 US Tariff Shock
  % Loss-20.3%-18.8%
  % Gain to Breakeven25.5%23.1%
  Time to Breakeven11 days79 days
Summer-Fall 2023 Five Percent Yield Shock
  % Loss-56.0%-9.5%
  % Gain to Breakeven127.2%10.5%
  Time to Breakeven436 days24 days
2023 SVB Regional Banking Crisis
  % Loss-30.5%-6.7%
  % Gain to Breakeven43.9%7.1%
  Time to Breakeven665 days31 days
2020 COVID-19 Crash
  % Loss-49.4%-33.7%
  % Gain to Breakeven97.6%50.9%
  Time to Breakeven51 days140 days

Compare to NTRA, GH, ILMN, TXG, QGEN

In The Past

Adaptive Biotechnologies's stock fell -20.3% during the 2025 US Tariff Shock. Such a loss loss requires a 25.5% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

About Adaptive Biotechnologies (ADPT)

Adaptive Biotechnologies (ADPT) is a commercial-stage company specializing in immune medicine, leveraging a proprietary immunosequencing platform to diagnose, monitor, and treat various diseases. The company's core technology analyzes the adaptive immune system, specifically the T-cell and B-cell receptors, to generate insights into disease states and therapeutic responses. This approach allows for a deep understanding of the body's immune reaction to illnesses such as cancer, autoimmune conditions, and infectious diseases.

The company's main products and services include immunoSEQ, a platform for translational research and discovering diagnostic signals, and clonoSEQ, a clinical diagnostic test used to detect and monitor minimal residual disease (MRD) in patients with specific blood cancers like multiple myeloma, B-cell acute lymphoblastic leukemia, and chronic lymphocytic leukemia. Additionally, Adaptive offers T-Detect COVID for confirming past COVID-19 infections and immunoSEQ T-MAP COVID for vaccine developers to measure T-cell immune responses to vaccines. Beyond these, the company is developing a pipeline of clinical products and services aimed at broader diagnostic and therapeutic applications.

Adaptive Biotechnologies serves a broad range of customers and markets, including life sciences research, clinical diagnostics, and drug discovery applications. The company has established key strategic collaborations that extend its reach into new areas. Notably, it partners with Genentech to develop neoantigen-directed T-cell therapies for various cancers and with Microsoft to create advanced diagnostic tests for the early detection of diseases from a single blood test, highlighting its commitment to advancing immune-driven medicine.

AI Analysis | Feedback

Here are 1-3 brief analogies to describe Adaptive Biotechnologies (ADPT):

  • Like Illumina, but specialized in "reading" the immune system's genetic code for disease detection and therapy.
  • Like Guardant Health, but focused on immune sequencing to detect and monitor blood cancers and track overall immune responses.
  • Like an "Ancestry.com for your immune system," mapping its history and current activity to reveal insights into health and disease.

AI Analysis | Feedback

  • immunoSEQ: A core immunosequencing platform and product used for translational research and discovering prognostic and diagnostic signals.
  • T-Detect COVID: A diagnostic test for confirming past COVID-19 infection.
  • clonoSEQ: A clinical diagnostic product for detecting and monitoring minimal residual disease in patients with various lymphoid cancers.
  • immunoSEQ T-MAP COVID: A tool for vaccine developers and researchers to measure the T-cell immune response to vaccines.
  • Clinical Products and Services Pipeline: A pipeline of clinical products and services under development for diagnosing, monitoring, and treating diseases like cancer, autoimmune conditions, and infectious diseases.

AI Analysis | Feedback

Adaptive Biotechnologies (ADPT) primarily sells its products and services to other companies and institutions rather than directly to individuals. Based on the company description, it serves customers in the following key categories:

  1. Life Sciences Research & Academic Institutions: These customers utilize platforms like immunoSEQ for translational research questions, to discover new prognostic and diagnostic signals, and for other general research applications.

  2. Biopharmaceutical Companies (Drug Discovery & Vaccine Developers): This category includes companies engaged in drug discovery and development. They use Adaptive's platforms, such as immunoSEQ T-MAP COVID, to measure T-cell immune responses to vaccines and for broader applications in identifying and validating therapeutic targets.

  3. Clinical Diagnostic Laboratories & Healthcare Providers: These customers use Adaptive's clinical diagnostic products like clonoSEQ for the detection and monitoring of minimal residual disease in cancer patients, and T-Detect COVID for confirming past COVID-19 infections. While these tests are for individual patients, the direct customer is typically the clinic, hospital, or reference laboratory ordering and performing the tests.

AI Analysis | Feedback

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AI Analysis | Feedback

Chad Robins, Chief Executive Officer, Co-founder, Chairman of the Board
Chad Robins co-founded Adaptive Biotechnologies in 2009. He led the company through its initial public offering in 2019. Prior to founding Adaptive, he held executive-level positions in medical technology, investment banking, real estate, and private equity companies. He has a background in finance and operations, and his brother Harlan Robins, called upon him to help raise initial capital and run Adaptive Biotechnologies.

Kyle Piskel, Chief Financial Officer
Kyle Piskel was appointed Chief Financial Officer of Adaptive Biotechnologies, effective April 8, 2024. He joined the company in 2015 and has held various finance and accounting positions of increasing responsibility, including Corporate Controller and Principal Accounting Officer. Before joining Adaptive, he worked at Expedia Group and Ernst & Young, LLP. He is a Certified Public Accountant.

Harlan Robins, PhD, Chief Scientific Officer & Co-founder
Dr. Harlan Robins is a co-founder of Adaptive Biotechnologies, which was spun out of the Fred Hutchinson Cancer Research Center in 2009. As a computational biologist, his expertise in high-throughput genomic sequencing technology was instrumental to Adaptive's founding. He previously served as Head of the Computational Biology Program at the Fred Hutchinson Cancer Research Center. Dr. Robins also held postdoctoral appointments at the Weizmann Institute of Science and the Institute for Advance Study in Princeton, where he focused on developing bioinformatic algorithms.

Julie Rubinstein, President & Chief Operating Officer
Julie Rubinstein serves as President of Adaptive Biotechnologies, a role she has held since 2011. She oversees Life Sciences Research, Clinical Diagnostics, Drug Discovery, Corporate Marketing, and Business Development functions. Ms. Rubinstein was part of the executive team that led the company through its initial public offering in 2019. Prior to her tenure at Adaptive, she held various worldwide commercial development roles at Pfizer Oncology, with a focus on cancer immunotherapy.

Sharon Benzeno, PhD, Chief Commercial Officer, Immune Medicine
Dr. Sharon Benzeno joined Adaptive Biotechnologies in 2014 and currently serves as the Chief Commercial Officer, Immune Medicine. She also leads the Drug Discovery group. Before joining Adaptive, Dr. Benzeno was a Senior Director at Elsevier Inc., a healthcare informatics company. Her prior experience includes co-leading the oncology business unit at Capgemini SE, a consulting and technology services company, and various management roles at AstraZeneca plc. She holds a PhD in Biomedical Sciences and an MBA in Finance and Leadership from New York University.

AI Analysis | Feedback

Here are the key risks to Adaptive Biotechnologies (ADPT):
  1. Ongoing Financial Losses and Path to Profitability: Adaptive Biotechnologies has consistently reported significant net losses and accumulated deficits, reflecting high development and commercialization costs. The company's ability to achieve and sustain profitability remains uncertain, despite its investments in its immune medicine platform and product validation.
  2. Intense Competition and Need for Continuous Innovation: The biotechnology and pharmaceutical industries are highly competitive, with numerous companies pursuing advancements in immune medicine. Adaptive Biotechnologies faces competition in its core areas, including minimal residual disease (MRD) detection and immune repertoire sequencing, from larger companies with greater resources and new market entrants. The company's long-term success hinges on its capacity for continuous innovation to maintain its competitive edge.
  3. Reliance on Strategic Collaborations and Regulatory Landscape: Adaptive Biotechnologies depends significantly on strategic collaborations with partners such as Genentech, Microsoft, NeoGenomics, BeiGene, and Takeda for the development, manufacture, and commercialization of its diagnostic and therapeutic products. The termination or alteration of these key partnerships, including a past termination with Genentech for cancer cell therapy research, could adversely affect its business. Additionally, operating in a heavily regulated industry means the company is subject to strict regulatory approval processes for its clinical products (e.g., clonoSEQ) and faces risks from potential changes in regulations or compliance violations.

AI Analysis | Feedback

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AI Analysis | Feedback

Adaptive Biotechnologies Corporation (ADPT) operates in several key markets with its primary products and services.

clonoSEQ

The addressable market for clonoSEQ, which is used for the detection and monitoring of minimal residual disease (MRD) in various lymphoid cancers, is substantial and growing.

  • The global minimal residual disease testing market was valued at approximately USD 1.09 billion in 2021 and is projected to reach around USD 3.70 billion by 2030, exhibiting a compound annual growth rate (CAGR) of 14.53% from 2022 to 2030.
  • In the U.S. alone, the minimal residual disease testing market was estimated at USD 873.66 million in 2024 and is expected to continue growing through 2033.
  • The market in the 7MM (United States, the EU-4 (Italy, Spain, France, and Germany), the United Kingdom, and Japan) was approximately USD 700 million in 2021.

immunoSEQ

The immunoSEQ platform, used for translational research and discovering new prognostic and diagnostic signals, falls within the immune repertoire sequencing market.

  • The global immune repertoire sequencing market size was estimated at USD 328.2 million in 2024 and is projected to reach USD 894.2 million by 2033, with a CAGR of 11.89% from 2025 to 2033.
  • North America held the largest share of the global immune repertoire sequencing market, accounting for 41.91% in 2024.

AI Analysis | Feedback

Adaptive Biotechnologies (ADPT) is expected to drive future revenue growth over the next 2-3 years through several key strategies centered on its Minimal Residual Disease (MRD) business, particularly the clonoSEQ platform. Here are the expected drivers of future revenue growth: * Increased Adoption and Expanded Utilization of clonoSEQ: Adaptive Biotechnologies anticipates significant growth in clonoSEQ test volumes, driven by increased adoption of blood-based testing and expanded use in community settings. The company aims for over 30% growth in clonoSEQ test volumes in 2026. This expansion is further supported by significant Electronic Medical Record (EMR) integrations, such as with Flatiron's OncoEMR, which broadens access in the community setting. The recognition of clonoSEQ as a standard for assessing minimal residual disease in various blood cancers, as highlighted by its increasing presence in clinical trials and inclusion in NCCN guidelines for conditions like Chronic Lymphocytic Leukemia (CLL), is also expected to enhance its market position and clinical adoption. * Growth in Average Selling Price (ASP) for clonoSEQ: The company has successfully increased its Average Selling Price for clonoSEQ and projects further increases. For instance, Adaptive Biotechnologies is targeting an average US clinical ASP of approximately $1,400 per test in 2026. This growth is attributed to strategic contract renegotiations and improved revenue cycle management, directly contributing to higher revenue per test performed. Additionally, a new Medicare reimbursement rate of $2,007 for clonoSEQ, effective January 1, 2025, reflects its value in patient care and is expected to further enhance its market reach by facilitating new payer agreements and expanding coverage. * Revenue from MRD Pharma Partnerships and Milestones: Adaptive Biotechnologies continues to generate revenue from its Minimal Residual Disease (MRD) pharma partnerships, including regulatory milestone payments. For the full year 2025, the company recognized $19.5 million in milestone revenue, with a reported backlog of approximately $210 million at year-end. Although the collaboration with Genentech is winding down, Adaptive Biotechnologies continues to engage in other pharma services and collaborations that leverage its immune medicine platform for drug discovery and development, providing ongoing, albeit potentially variable, revenue streams.

AI Analysis | Feedback

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Share Issuance

  • Adaptive Biotechnologies has historically funded its operations through the sale of common stock. [5]
  • The number of shares outstanding for Adaptive Biotechnologies increased to 154 million in Q4 2025, reflecting a 0.7% increase from the prior quarter. [6]
  • In March 2026, the CEO, Chad M. Robins, received 709,220 shares and 127,813 shares of common stock from the vesting of performance share units granted in March 2023. [19] Additionally, President and COO Julie Rubinstein exercised stock options for 68,328 shares in March 2026. [1]

Inbound Investments

  • Adaptive Biotechnologies recognized $19.5 million in MRD (Minimal Residual Disease) pharma regulatory milestone revenue for the full year 2025. [12]
  • The company reported $6.5 million in MRD pharma regulatory milestone revenue in Q3 2025. [10]
  • In December 2025, Adaptive Biotechnologies announced two non-exclusive immune receptor licensing agreements with Pfizer. [13, 20] The strategic collaboration and license agreement with Genentech was terminated. [1]

Capital Expenditures

  • Adaptive Biotechnologies invested $636,000 in capital expenditures during Q4 2025 to fund long-term assets and infrastructure. [6]
  • For the full year 2025, capital expenditures totaled $3.0 million. [6]
  • The company implemented the NovaSeq X Plus platform for clonoSEQ clinical sequencing, indicating a primary focus on enhancing its diagnostic capabilities. [12]
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Better Bets vs. Adaptive Biotechnologies (ADPT)

Recent Active Movers

Peer Comparisons

Peers to compare with:

Financials

ADPTNTRAGHILMNTXGQGENMedian
NameAdaptive.Natera Guardant.Illumina 10x Geno.Qiagen  
Mkt Price20.25260.74142.94177.6535.7338.9490.94
Mkt Cap3.136.918.827.24.68.113.4
Rev LTM2952,5011,0804,3936392,0991,590
Op Inc LTM-47-324-448861-79512-63
FCF LTM-3072-23797412240497
FCF 3Y Avg-88-14-281739314229
CFO LTM-27211-1881,128128615169
CFO 3Y Avg-8375-2478915360564

Growth & Margins

ADPTNTRAGHILMNTXGQGENMedian
NameAdaptive.Natera Guardant.Illumina 10x Geno.Qiagen  
Rev Chg LTM55.9%36.6%39.6%1.3%2.3%4.8%20.7%
Rev Chg 3Y Avg19.7%42.5%31.0%-0.4%6.3%1.7%13.0%
Rev Chg Q35.1%38.8%48.3%4.8%-2.6%1.8%20.0%
QoQ Delta Rev Chg LTM6.7%8.4%10.0%1.2%-0.6%0.4%3.9%
Op Inc Chg LTM65.7%-42.7%1.6%0.2%56.3%125.6%28.9%
Op Inc Chg 3Y Avg31.9%9.1%6.8%10.9%17.1%23.9%14.0%
Op Mgn LTM-15.8%-13.0%-41.4%19.6%-12.4%24.4%-12.7%
Op Mgn 3Y Avg-66.1%-19.0%-62.7%11.0%-25.2%19.5%-22.1%
QoQ Delta Op Mgn LTM4.8%0.5%3.1%0.8%4.8%-0.5%2.0%
CFO/Rev LTM-9.2%8.4%-17.4%25.7%20.0%29.3%14.2%
CFO/Rev 3Y Avg-43.9%1.8%-33.0%20.3%8.3%30.0%5.0%
FCF/Rev LTM-10.0%2.9%-22.0%22.2%19.1%19.2%11.0%
FCF/Rev 3Y Avg-46.6%-2.8%-37.1%16.8%4.8%20.9%1.0%

Valuation

ADPTNTRAGHILMNTXGQGENMedian
NameAdaptive.Natera Guardant.Illumina 10x Geno.Qiagen  
Mkt Cap3.136.918.827.24.68.113.4
P/S10.714.817.46.27.23.88.9
P/Op Inc-67.4-113.8-41.931.6-57.715.8-49.8
P/EBIT-83.1-130.8-43.623.4117.116.3-13.7
P/E-63.4-163.0-43.331.9-202.320.0-53.4
P/CFO-116.5174.8-100.024.135.913.118.6
Total Yield-1.6%-0.6%-2.3%3.1%-0.5%5.0%-0.6%
Dividend Yield0.0%0.0%0.0%0.0%0.0%-0.0%0.0%
FCF Yield 3Y Avg-13.4%-0.3%-6.6%4.6%2.3%4.8%1.0%
D/E0.00.00.10.10.00.20.1
Net D/E-0.0-0.00.00.1-0.10.10.0

Returns

ADPTNTRAGHILMNTXGQGENMedian
NameAdaptive.Natera Guardant.Illumina 10x Geno.Qiagen  
1M Rtn43.3%29.8%19.3%22.3%45.1%9.6%26.1%
3M Rtn45.1%32.9%62.2%42.8%74.9%-1.9%43.9%
6M Rtn21.4%10.7%39.6%31.3%114.1%-14.5%26.3%
12M Rtn69.0%58.8%186.5%90.6%206.4%-17.6%79.8%
3Y Rtn200.9%423.0%300.7%-4.7%-34.8%-11.0%98.1%
1M Excs Rtn45.5%31.9%21.4%24.5%47.3%11.7%28.2%
3M Excs Rtn31.5%20.5%53.5%29.2%59.3%-15.8%30.3%
6M Excs Rtn9.3%3.7%34.1%22.1%104.0%-22.5%15.7%
12M Excs Rtn69.4%30.9%165.2%73.3%207.3%-38.0%71.4%
3Y Excs Rtn77.8%332.8%216.3%-77.2%-105.9%-80.3%0.3%

Comparison Analyses

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Financials

Segment Financials

Revenue by Segment
$ Mil20252024202320222021
Minimal Residual Disease (MRD)2121461038766
Immune Medicine6533689888
Total277179170185154


Price Behavior

Price Behavior
Market Price$20.25 
Market Cap ($ Bil)3.1 
First Trading Date06/27/2019 
Distance from 52W High-1.0% 
   50 Days200 Days
DMA Price$15.19$15.57
DMA Trendupup
Distance from DMA33.3%30.0%
 3M1YR
Volatility78.0%67.9%
Downside Capture98.60170.90
Upside Capture184.90193.95
Correlation (SPY)44.6%33.4%
ADPT Betas & Captures as of 5/31/2026

 1M2M3M6M1Y3Y
Beta1.202.602.521.701.811.77
Up Beta3.384.233.572.682.461.79
Down Beta0.87-0.373.061.400.820.94
Up Capture87%116%147%82%293%1809%
Bmk +ve Days13283667141432
Stock +ve Days11213462126356
Down Capture-11%286%224%169%153%113%
Bmk -ve Days7132757109318
Stock -ve Days9192861121384

[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with ADPT
ADPT86.4%69.0%1.19-
Sector ETF (XLV)17.9%15.1%0.8831.6%
Equity (SPY)22.1%12.4%1.3333.6%
Gold (GLD)20.8%27.7%0.6715.0%
Commodities (DBC)23.3%18.5%0.99-19.3%
Real Estate (VNQ)11.6%13.8%0.5516.6%
Bitcoin (BTCUSD)-42.9%42.5%-1.2011.1%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 5-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with ADPT
ADPT-13.0%78.5%0.16-
Sector ETF (XLV)6.2%14.8%0.2335.1%
Equity (SPY)13.3%17.1%0.6044.2%
Gold (GLD)17.4%18.3%0.779.4%
Commodities (DBC)7.9%19.5%0.303.1%
Real Estate (VNQ)2.8%18.9%0.0539.7%
Bitcoin (BTCUSD)9.8%54.1%0.3822.6%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 10-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with ADPT
ADPT-6.9%76.6%0.21-
Sector ETF (XLV)10.1%16.6%0.4933.8%
Equity (SPY)15.3%18.0%0.7341.0%
Gold (GLD)11.6%16.1%0.599.9%
Commodities (DBC)5.9%18.0%0.255.9%
Real Estate (VNQ)5.5%20.7%0.2333.6%
Bitcoin (BTCUSD)56.4%66.5%0.9722.4%

Smart multi-asset allocation framework can stack odds in your favor. Learn How

Short Interest

Short Interest: As Of Date6152026
Short Interest: Shares Quantity7.6 Mil
Short Interest: % Change Since 5312026-7.2%
Average Daily Volume2.7 Mil
Days-to-Cover Short Interest2.8 days
Basic Shares Quantity155.5 Mil
Short % of Basic Shares4.9%

Earnings Returns History

Updated 6/7/2026
Expand for More
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
5/5/20264.7%-1.1%31.2%
2/5/2026-4.3%-5.6%-9.2%
11/5/2025-11.5%-17.6%-15.0%
8/5/20255.8%14.6%17.8%
5/1/202533.7%26.0%29.8%
2/11/2025-3.2%7.3%-8.1%
11/7/20243.4%-0.9%14.4%
8/1/2024-3.4%-1.1%5.6%
...
SUMMARY STATS   
# Positive14812
# Negative101612
Median Positive5.2%15.5%10.7%
Median Negative-4.8%-5.9%-15.0%
Max Positive33.7%27.6%31.2%
Max Negative-18.2%-29.8%-33.8%
Collapse to Preview
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
5/5/20264.7%-1.1%31.2%
2/5/2026-4.3%-5.6%-9.2%
11/5/2025-11.5%-17.6%-15.0%
8/5/20255.8%14.6%17.8%
5/1/202533.7%26.0%29.8%
2/11/2025-3.2%7.3%-8.1%
11/7/20243.4%-0.9%14.4%
8/1/2024-3.4%-1.1%5.6%
5/7/20242.3%27.3%25.4%
2/14/20240.5%-1.5%-17.8%
11/9/2023-18.2%-6.1%7.0%
8/2/2023-12.4%-18.5%-14.9%
5/3/2023-14.3%-5.1%-0.5%
2/14/202315.6%1.7%-3.2%
11/3/202214.3%16.5%6.0%
8/3/202214.9%27.6%-9.7%
5/4/2022-4.3%-29.8%-25.0%
2/15/20225.2%-12.3%-15.5%
11/3/20215.2%-4.5%-27.6%
8/4/20210.9%-12.6%5.0%
5/5/20213.2%-7.2%1.3%
2/24/2021-5.3%-14.1%-33.8%
11/10/202010.3%-2.7%17.3%
8/10/2020-2.2%9.1%1.8%
SUMMARY STATS   
# Positive14812
# Negative101612
Median Positive5.2%15.5%10.7%
Median Negative-4.8%-5.9%-15.0%
Max Positive33.7%27.6%31.2%
Max Negative-18.2%-29.8%-33.8%

SEC Filings

Expand for More
Report DateFiling DateFiling
03/31/202605/05/202610-Q
12/31/202502/26/202610-K
09/30/202511/05/202510-Q
06/30/202508/05/202510-Q
03/31/202505/01/202510-Q
12/31/202403/03/202510-K
09/30/202411/07/202410-Q
06/30/202408/01/202410-Q
03/31/202405/07/202410-Q
12/31/202302/29/202410-K
09/30/202311/09/202310-Q
06/30/202308/02/202310-Q
03/31/202305/03/202310-Q
12/31/202202/14/202310-K
09/30/202211/03/202210-Q
06/30/202208/03/202210-Q
Collapse to Preview
Report DateFiling DateFiling
03/31/202605/05/202610-Q
12/31/202502/26/202610-K
09/30/202511/05/202510-Q
06/30/202508/05/202510-Q
03/31/202505/01/202510-Q
12/31/202403/03/202510-K
09/30/202411/07/202410-Q
06/30/202408/01/202410-Q
03/31/202405/07/202410-Q
12/31/202302/29/202410-K
09/30/202311/09/202310-Q
06/30/202308/02/202310-Q
03/31/202305/03/202310-Q
12/31/202202/14/202310-K
09/30/202211/03/202210-Q
06/30/202208/03/202210-Q
03/31/202205/04/202210-Q
12/31/202102/15/202210-K
09/30/202111/03/202110-Q
06/30/202108/04/202110-Q
03/31/202105/05/202110-Q
12/31/202002/24/202110-K
09/30/202011/10/202010-Q
06/30/202008/10/202010-Q
03/31/202005/12/202010-Q
12/31/201902/26/202010-K
09/30/201911/12/201910-Q
06/30/201908/13/201910-Q

Recent Forward Guidance

Updated 5/31/2026

Latest: Q1 2026 Earnings Reported 5/5/2026

Forward GuidanceGuidance Change
MetricLowMidHigh% Chg% DeltaChangePrior
2026 MRD Revenue260.00 Mil265.00 Mil270.00 Mil1.9% RaisedGuidance: 260.00 Mil for 2026
2026 Total Operating Expenses350.00 Mil355.00 Mil360.00 Mil0 AffirmedGuidance: 355.00 Mil for 2026

Prior: Q4 2025 Earnings Reported 2/5/2026

Forward GuidanceGuidance Change
MetricLowMidHigh% Chg% DeltaChangePrior
2026 MRD Revenue255.00 Mil260.00 Mil265.00 Mil27.1% RaisedGuidance: 204.50 Mil for 2025
2026 Operating Expenses350.00 Mil355.00 Mil360.00 Mil5.2% RaisedGuidance: 337.50 Mil for 2025

Insider Activity

Updated 6/17/2026
Expand for More
#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Robins, Harlan SChief Scientific OfficerDirectSell617202618.016,160110,94225,320,223Form
2Robins, Harlan SChief Scientific OfficerDirectSell617202617.37100,0001,737,00024,527,447Form
3Bobulsky, SusanChief Commercial Officer, MRDDirectSell615202619.005,00095,0007,823,725Form
4Bobulsky, SusanChief Commercial Officer, MRDDirectSell608202618.0011,000198,0007,501,950Form
5Lo, FrancisChief People OfficerDirectSell604202617.4939,741695,0704,388,836Form
Collapse to Preview
#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Robins, Harlan SChief Scientific OfficerDirectSell617202618.016,160110,94225,320,223Form
2Robins, Harlan SChief Scientific OfficerDirectSell617202617.37100,0001,737,00024,527,447Form
3Bobulsky, SusanChief Commercial Officer, MRDDirectSell615202619.005,00095,0007,823,725Form
4Bobulsky, SusanChief Commercial Officer, MRDDirectSell608202618.0011,000198,0007,501,950Form
5Lo, FrancisChief People OfficerDirectSell604202617.4939,741695,0704,388,836Form
6Piskel, KyleChief Financial OfficerDirectSell520202613.043,11540,6203,347,694Form
7Rubinstein, JuliePresident and COODirectSell429202614.2319,037270,8975,376,122Form
8Rubinstein, JuliePresident and COODirectSell424202614.0219,060267,2215,357,491Form
9Rubinstein, JuliePresident and COODirectSell424202613.7419,060261,8845,310,098Form
10Rubinstein, JuliePresident and COODirectSell424202614.1319,060269,3185,522,117Form
11Rubinstein, JuliePresident and COODirectSell421202614.6630,941453,5955,792,840Form
12Rubinstein, JuliePresident and COODirectSell421202614.5519,060277,3235,812,492Form
13Rubinstein, JuliePresident and COODirectSell421202614.5719,060277,7045,883,687Form
14Rubinstein, JuliePresident and COODirectSell416202614.1819,060270,2715,787,709Form
15Rubinstein, JuliePresident and COODirectSell416202614.6119,060278,4676,026,596Form
16Rubinstein, JuliePresident and COODirectSell416202614.5619,060277,5146,069,132Form
17Rubinstein, JuliePresident and COODirectSell413202613.1519,060250,5995,537,553Form
18Rubinstein, JuliePresident and COODirectSell413202612.7719,060243,3075,431,797Form
19Rubinstein, JuliePresident and COODirectSell413202613.8619,060264,2025,958,416Form
20Robins, Harlan SChief Scientific OfficerDirectSell410202614.8510,000148,50022,454,061Form
21Lo, FrancisChief People OfficerDirectSell410202615.0722,564340,0394,086,291Form
22Rubinstein, JuliePresident and COODirectSell408202614.8330,941458,9206,439,920Form
23Robins, Chad MCEO and ChairmanDirectSell408202615.1937,263566,02533,122,068Form
24Rubinstein, JuliePresident and COODirectSell408202613.5619,060258,4545,946,413Form
25Rubinstein, JuliePresident and COODirectSell408202614.3319,060273,1306,346,241Form
26Robins, Chad MCEO and ChairmanDirectSell408202614.4183,3321,200,81431,958,224Form
27Rubinstein, JuliePresident and COODirectSell402202614.6019,060278,2766,529,149Form
28Rubinstein, JuliePresident and COODirectSell402202614.4519,060275,4176,524,753Form
29Rubinstein, JuliePresident and COODirectSell331202613.4519,060256,3576,131,559Form
30Rubinstein, JuliePresident and COODirectSell331202612.6319,060240,7285,812,528Form
31Rubinstein, JuliePresident and COODirectSell331202613.3419,060254,2186,196,121Form
32Rubinstein, JuliePresident and COODirectSell326202614.1219,060269,1276,620,755Form
33Rubinstein, JuliePresident and COODirectSell326202614.2719,060271,9866,752,992Form
34Rubinstein, JuliePresident and COODirectSell326202613.7019,060261,1226,542,682Form
35Rubinstein, JuliePresident and COODirectSell323202613.8319,060263,6006,664,760Form
36Rubinstein, JuliePresident and COODirectSell323202613.3719,060254,8326,501,082Form
37Rubinstein, JuliePresident and COODirectSell323202613.1819,060251,2116,465,871Form
38Rubinstein, JuliePresident and COODirectSell318202613.1819,060251,2116,523,046Form
39Rubinstein, JuliePresident and COODirectSell318202613.4019,060255,4046,690,057Form
40Rubinstein, JuliePresident and COODirectSell318202613.4119,060255,5956,753,222Form
41Rubinstein, JuliePresident and COODirectSell313202612.9619,060247,0186,582,825Form
42Rubinstein, JuliePresident and COODirectSell313202612.8619,060245,0486,586,103Form
43Rubinstein, JuliePresident and COODirectSell313202613.29141,5831,881,9936,867,041Form
44Griffin, Michelle Renee DirectSell313202613.9115,394214,131217,344Form
45Lo, FrancisChief People OfficerDirectSell313202614.0830,593430,7494,102,546Form
46Bobulsky, SusanChief Commercial Officer, MRDDirectSell313202613.1741,338544,4215,633,797Form
47Benzeno, SharonChief Commercial Ofc Imm MedDirectSell313202613.1763,103831,0673,592,131Form
48Piskel, KyleChief Financial OfficerDirectSell313202613.1718,672245,9103,422,093Form
49Robins, Harlan SChief Scientific OfficerDirectSell313202613.17470,2666,193,40320,045,504Form
50Robins, Chad MCEO and ChairmanDirectSell313202613.17470,1676,192,09930,305,658Form
51Lo, FrancisChief People OfficerDirectSell309202615.0938,074574,5374,858,482Form
52Rubinstein, JuliePresident and COODirectSell305202616.0030,941495,0569,203,760Form
53Rubinstein, JuliePresident and COODirectSell305202616.6030,941513,6219,620,912Form
54Rubinstein, JuliePresident and COODirectSell305202615.6730,941484,7519,148,107Form
55Griffin, Michelle Renee DirectSell305202615.3048,044735,073235,528Form
56Piskel, KyleChief Financial OfficerDirectSell206202618.462,14539,5973,999,119Form
57Robins, Harlan SChief Scientific OfficerDirectSell204202619.008,120154,28022,410,956Form
58Robins, Harlan SChief Scientific OfficerDirectSell204202618.6034,668644,82522,090,178Form
59Robins, Chad MCEO and ChairmanDirectSell204202618.44124,9982,304,96345,348,478Form
60Lo, FrancisChief People OfficerDirectSell114202617.7379,5901,411,1315,602,290Form
61Piskel, KyleChief Financial OfficerDirectSell114202618.004,29077,2203,899,466Form
62Lo, FrancisChief People OfficerDirectSell106202616.083,12550,2505,080,926Form
63Lo, FrancisChief People OfficerDirectSell1229202517.504,39476,8955,529,615Form
64Lo, FrancisChief People OfficerDirectSell1217202515.57113,8901,773,2674,919,777Form
65Hershberg, Robert DirectSell1212202516.0022,968367,488747,552Form
66Benzeno, SharonChief Commercial Ofc Imm MedDirectSell1208202516.8512,604212,3775,000,928Form
67Robins, Harlan SChief Scientific OfficerDirectSell1205202516.6110,000166,10020,468,702Form
68Robins, Harlan SChief Scientific OfficerDirectSell1205202518.6127,212506,41523,119,426Form
69Piskel, KyleChief Financial OfficerDirectSell1202202519.50162,8203,174,9904,224,422Form
70Robins, Chad MCEO and ChairmanDirectSell1201202518.94124,9982,367,46251,313,025Form
71Robins, Chad MCEO and ChairmanDirectSell1201202519.6835,736703,28455,777,824Form
72Benzeno, SharonChief Commercial Ofc Imm MedDirectSell1124202516.91308,4775,216,3465,018,736Form
73Benzeno, SharonChief Commercial Ofc Imm MedDirectSell1124202516.54297,9254,927,6804,908,923Form
74Piskel, KyleChief Financial OfficerDirectSell1118202514.052383,3443,784,269Form
75Robins, Chad MCEO and ChairmanDirectSell1112202515.001,86728,00543,049,625Form
76Robins, Chad MCEO and ChairmanDirectSell1112202514.571,23718,02341,842,869Form
77Robins, Harlan SChief Scientific OfficerDirectSell1112202514.8210,000148,20018,814,346Form
78Robins, Chad MCEO and ChairmanDirectSell1112202514.7386,1611,269,15242,320,586Form
Core Cache Last Updated: 6/25/2026