Tearsheet

UroGen Pharma (URGN)


Market Price (3/4/2026): $18.805 | Market Cap: $903.7 Mil
Sector: Health Care | Industry: Biotechnology

UroGen Pharma (URGN)


Market Price (3/4/2026): $18.805
Market Cap: $903.7 Mil
Sector: Health Care
Industry: Biotechnology

Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.

0 Megatrend and thematic drivers
Megatrends include Aging Population & Chronic Disease, and Precision Medicine. Themes include Oncology Treatments, Biopharmaceutical R&D, Show more.
Weak multi-year price returns
2Y Excs Rtn is -33%
Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -110 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -112%
1  Meaningful short interest
Short Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 19%
Stock price has recently run up significantly
12M Rtn12 month market price return is 103%
2   Significant share based compensation
SBC/Rev LTMShare Based Compensation / Revenue (Sales), Last Twelve Months (LTM) is 10%
3   Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -20%
4   High stock price volatility
Vol 12M is 114%
5   Significant short interest
Short Interest Days-to-CoverDTC = (Short Interest Share Quantity) / (Average Daily Trading Volume). Reflects how many days it would take to cover (close out) the short interest based on average volumes. High DTC can signify an increased risk of a short squeeze. is 15.12
6   Key risks
URGN key risks include [1] regulatory and commercial uncertainty for its lead candidate UGN-102 following criticism of its clinical trial design, Show more.
0 Megatrend and thematic drivers
Megatrends include Aging Population & Chronic Disease, and Precision Medicine. Themes include Oncology Treatments, Biopharmaceutical R&D, Show more.
1 Weak multi-year price returns
2Y Excs Rtn is -33%
2 Meaningful short interest
Short Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 19%
3 Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -110 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -112%
4 Stock price has recently run up significantly
12M Rtn12 month market price return is 103%
5 Significant share based compensation
SBC/Rev LTMShare Based Compensation / Revenue (Sales), Last Twelve Months (LTM) is 10%
6 Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -20%
7 High stock price volatility
Vol 12M is 114%
8 Significant short interest
Short Interest Days-to-CoverDTC = (Short Interest Share Quantity) / (Average Daily Trading Volume). Reflects how many days it would take to cover (close out) the short interest based on average volumes. High DTC can signify an increased risk of a short squeeze. is 15.12
9 Key risks
URGN key risks include [1] regulatory and commercial uncertainty for its lead candidate UGN-102 following criticism of its clinical trial design, Show more.

Valuation, Metrics & Events

Price Chart

Why The Stock Moved

Qualitative Assessment

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UroGen Pharma (URGN) stock has lost about 35% since 11/30/2025 because of the following key factors:

1. Q4 2025 Earnings and Revenue Miss: UroGen Pharma reported its fourth-quarter 2025 earnings on March 2, 2026, with an earnings per share (EPS) of -$0.54, missing analyst expectations by 12.5%. Additionally, the company's revenue for the quarter was $37.84 million, falling short of the forecasted $41.45 million by 8.71%.

2. Widening Annual Net Loss and Increased Operating Expenses: For the full year ended December 31, 2025, UroGen Pharma reported a net loss of $153.5 million, or $3.19 per basic and diluted share, which widened from a net loss of $126.9 million in 2024. This increase was attributed to higher operating expenses, with research and development expenses rising to $67.1 million and selling, general, and administrative expenses increasing to $155.1 million in 2025.

Show more

Stock Movement Drivers

Fundamental Drivers

The -34.7% change in URGN stock from 11/30/2025 to 3/3/2026 was primarily driven by a -34.7% change in the company's P/S Multiple.
(LTM values as of)113020253032026Change
Stock Price ($)28.8118.82-34.7%
Change Contribution By: 
Total Revenues ($ Mil)98980.0%
P/S Multiple14.29.3-34.7%
Shares Outstanding (Mil)48480.0%
Cumulative Contribution-34.7%

LTM = Last Twelve Months as of date shown

Market Drivers

11/30/2025 to 3/3/2026
ReturnCorrelation
URGN-34.7% 
Market (SPY)-0.4%7.7%
Sector (XLV)-0.6%21.1%

Fundamental Drivers

The -3.2% change in URGN stock from 8/31/2025 to 3/3/2026 was primarily driven by a -7.6% change in the company's P/S Multiple.
(LTM values as of)83120253032026Change
Stock Price ($)19.4518.82-3.2%
Change Contribution By: 
Total Revenues ($ Mil)92986.1%
P/S Multiple10.09.3-7.6%
Shares Outstanding (Mil)4748-1.3%
Cumulative Contribution-3.2%

LTM = Last Twelve Months as of date shown

Market Drivers

8/31/2025 to 3/3/2026
ReturnCorrelation
URGN-3.2% 
Market (SPY)5.8%12.6%
Sector (XLV)14.6%18.9%

Fundamental Drivers

The 98.9% change in URGN stock from 2/28/2025 to 3/3/2026 was primarily driven by a 87.3% change in the company's P/S Multiple.
(LTM values as of)22820253032026Change
Stock Price ($)9.4618.8298.9%
Change Contribution By: 
Total Revenues ($ Mil)89989.1%
P/S Multiple5.09.387.3%
Shares Outstanding (Mil)4748-2.7%
Cumulative Contribution98.9%

LTM = Last Twelve Months as of date shown

Market Drivers

2/28/2025 to 3/3/2026
ReturnCorrelation
URGN98.9% 
Market (SPY)15.5%17.5%
Sector (XLV)6.6%25.4%

Fundamental Drivers

The 82.7% change in URGN stock from 2/28/2023 to 3/3/2026 was primarily driven by a 146.6% change in the company's P/S Multiple.
(LTM values as of)22820233032026Change
Stock Price ($)10.3018.8282.7%
Change Contribution By: 
Total Revenues ($ Mil)629856.2%
P/S Multiple3.89.3146.6%
Shares Outstanding (Mil)2348-52.6%
Cumulative Contribution82.7%

LTM = Last Twelve Months as of date shown

Market Drivers

2/28/2023 to 3/3/2026
ReturnCorrelation
URGN82.7% 
Market (SPY)78.1%13.8%
Sector (XLV)29.0%16.5%

Return vs. Risk

Price Returns Compared

 202120222023202420252026Total [1]
Returns
URGN Return-47%-7%69%-29%120%-19%6%
Peers Return-10%14%-9%-13%16%104%93%
S&P 500 Return27%-19%24%23%16%1%83%

Monthly Win Rates [3]
URGN Win Rate42%42%50%33%75%33% 
Peers Win Rate42%65%42%43%57%80% 
S&P 500 Win Rate75%42%67%75%67%67% 

Max Drawdowns [4]
URGN Max Drawdown-50%-46%-10%-30%-63%-20% 
Peers Max Drawdown-21%-17%-32%-23%-24%-1% 
S&P 500 Max Drawdown-1%-25%-1%-2%-15%-1% 


[1] Cumulative total returns since the beginning of 2021
[2] Peers: CGON, IBRX, JNJ, MRK, BMY.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 3/3/2026 (YTD)

How Low Can It Go

Unique KeyEventURGNS&P 500
2022 Inflation Shock2022 Inflation Shock  
2022 Inflation Shock% Loss% Loss-81.0%-25.4%
2022 Inflation Shock% Gain to Breakeven% Gain to Breakeven426.6%34.1%
2022 Inflation ShockTime to BreakevenTime to Breakeven1,280 days464 days
2020 Covid Pandemic2020 Covid Pandemic  
2020 Covid Pandemic% Loss% Loss-60.5%-33.9%
2020 Covid Pandemic% Gain to Breakeven% Gain to Breakeven152.9%51.3%
2020 Covid PandemicTime to BreakevenTime to BreakevenNot Fully Recovered days148 days
2018 Correction2018 Correction  
2018 Correction% Loss% Loss-67.7%-19.8%
2018 Correction% Gain to Breakeven% Gain to Breakeven209.5%24.7%
2018 CorrectionTime to BreakevenTime to BreakevenNot Fully Recovered days120 days

Compare to CGON, IBRX, JNJ, MRK, BMY

In The Past

UroGen Pharma's stock fell -81.0% during the 2022 Inflation Shock from a high on 2/10/2021. A -81.0% loss requires a 426.6% gain to breakeven.

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About UroGen Pharma (URGN)

UroGen Pharma Ltd., a biotechnology company, engages in the development and commercialization novel solutions for specialty cancers and urothelial diseases. It offers RTGel, a polymeric biocompatible and reverse thermal gelation hydrogel to improve therapeutic profiles of existing drugs; and Jelmyto for pyelocalyceal solution. The company's lead product candidate is UGN-102, which is in Phase III clinical trials for the treatment of several forms of non-muscle invasive urothelial cancer that include low-grade upper tract urothelial carcinoma and low-grade non-muscle invasive bladder cancer. It is also developing UGN-301 for the treatment of high-grade non-muscle invasive bladder cancer. The company has a license agreement with Allergan Pharmaceuticals International Limited for developing and commercializing pharmaceutical products that contain RTGel and clostridial toxins; Agenus Inc. to develop, make, use, sell, import, and commercialize products of Agenus for the treatment of cancers of the urinary tract via intravesical delivery; and strategic research collaboration with MD Anderson to advance investigational treatment for high-grade bladder cancer. UroGen Pharma Ltd. was incorporated in 2004 and is based in Princeton, New Jersey.

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Here are 1-3 brief analogies for UroGen Pharma (URGN):

  • Vertex Pharmaceuticals for urothelial cancers.
  • A highly specialized Bristol Myers Squibb, focused exclusively on specific urological cancers.

AI Analysis | Feedback

  • JELMYTO (mitomycin) for pyelocalyceal solution: The first and only non-surgical treatment approved for low-grade upper tract urothelial cancer (UTUC).
  • UGN-102 (mitomycin) for intravesical solution: An investigational product currently in Phase 3 clinical trials for the treatment of low-grade intermediate-risk non-muscle invasive bladder cancer (LG-IR-NMIBC).

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UroGen Pharma (URGN) sells primarily to other companies, specifically to a limited number of wholesale distributors who then supply the company's products to specialty pharmacies, hospitals, and other healthcare providers.

According to its SEC filings, the company's major customers, which are wholesale distributors, are:

  • McKesson Corporation (NYSE: MCK)
  • AmerisourceBergen Corporation (NYSE: ABC)
  • Cardinal Health, Inc. (NYSE: CAH)

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  • Recipharm
  • Evonik Industries AG (Symbol: EVK.DE)

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Liz Barrett, President and Chief Executive Officer

Ms. Barrett was appointed CEO of UroGen Pharma in January 2019. She is a highly regarded industry leader with extensive experience in leading business organizations and Fortune 500 pharmaceutical companies. Prior to UroGen, she served as CEO of Novartis Oncology and was a member of the Novartis Executive Committee. She also held the position of Global President of Oncology at Pfizer Inc., where her leadership roles included President of Global Innovative Pharma for Europe, President of the Specialty Care Business Unit for North America, and President of United States Oncology. Before Pfizer, Ms. Barrett worked at Cephalon Inc. as Vice President and General Manager of the Oncology Business Unit, and at Johnson & Johnson. She began her career at Kraft Food Groups, Inc. Ms. Barrett has overseen the launch of major cancer drugs, including Ibrance (palbociclib) at Pfizer and was involved in the commercialization of Kymriah (tisagenlecleucel) at Novartis.

Chris Degnan, Chief Financial Officer

Mr. Degnan was appointed Chief Financial Officer in October 2024. He brings extensive experience as a CFO for publicly traded biotech companies, having most recently served in this role at Galera Therapeutics and Verrica Pharmaceuticals. His expertise spans financial strategy, investor relations, SEC reporting, accounting, and compliance. Earlier in his career, Mr. Degnan held senior positions at Endo International plc and spent over 10 years at the global biopharmaceutical company AstraZeneca plc. He is a Certified Public Accountant.

Mark P. Schoenberg, M.D., Chief Medical Officer

Dr. Schoenberg joined UroGen Pharma in 2017. He is an internationally recognized expert in the treatment of urothelial cancer, with significant contributions to peer-reviewed literature in urologic oncology. Dr. Schoenberg held prominent academic positions, including the Bernard Schwartz Distinguished Professor of Urologic Oncology at Johns Hopkins University from 2005 to 2014. He completed his fellowship in urologic oncology at The James Buchanan Brady Urological Institute of Johns Hopkins University. He also served as a resident in surgery and urology at the Hospital of The University of Pennsylvania and earned his medical degree from The University of Texas (Houston). He is a founding member of the scientific advisory board of The Bladder Cancer Advocacy Network. In 2014, he was named Professor and University Chair of Urology at the Albert Einstein College of Medicine.

Jason Smith, General Counsel and Chief Compliance Officer

Mr. Smith joined UroGen Pharma in 2020. He is an experienced lawyer with extensive background in healthcare, pharmaceutical, and corporate law. Before his tenure at UroGen, he served as Chief Counsel, Oncology at Pfizer. Prior to Pfizer, Mr. Smith worked in the legal department at Wyeth, where he held various roles, including antitrust counsel, Global Product Counsel, and Chief Counsel, U.S. Pharmaceuticals. He began his legal career as an associate at Howrey, Simon, Arnold & White in Washington, D.C., focusing on antitrust and commercial litigation.

AI Analysis | Feedback

UroGen Pharma (URGN) faces several key business risks, primarily centered around regulatory hurdles for its product pipeline, its challenging financial health, and the complexities of market penetration and competition. The most significant risk stems from **regulatory hurdles and clinical trial outcomes for its product candidates, particularly UGN-102**. The FDA's Oncologic Drugs Advisory Committee (ODAC) voted against UGN-102 due to concerns over deficiencies in its clinical trial design, specifically the lack of a concurrent control arm. This resulted in substantial drops in UroGen's stock price and initiated class-action lawsuits alleging misleading statements to investors. While UGN-102 may have later received approval, its commercial viability and widespread physician adoption remain uncertain given the established surgical standards it aims to replace. Secondly, **UroGen Pharma's financial health presents a notable risk due to ongoing profitability challenges and significant debt**. The company has reported negative operating and net margins, as well as negative free cash flow, indicating difficulties in achieving overall profitability despite revenue growth. Its financial strength is rated as poor, with considerable debt levels contributing to a distress zone Z-Score. There are concerns about a limited financial runway and the potential need for future capital raises or non-dilutive financing. Finally, **market penetration, intense competition, and ensuring product acceptance are significant challenges**. UroGen's business heavily relies on the successful commercialization of its approved products, like Jelmyto, and its product candidates. The company faces hurdles in achieving broad physician adoption and market acceptance, and the actual market opportunities for its therapies may be smaller than anticipated due to competition from existing treatments and new market entrants. Additionally, the high rates of adverse reactions and the necessity for repeat procedures associated with some of its treatments could hinder patient uptake and overall market performance.

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The emerging threat to UroGen Pharma (URGN) is the advanced development and potential commercialization of TAR-200 by Johnson & Johnson (Janssen) / TARIS Biomedical. TAR-200 is an intravesical drug delivery system designed for sustained release of therapeutic agents, currently undergoing evaluation in multiple clinical trials for bladder cancer. While some studies focus on high-risk non-muscle invasive bladder cancer (NMIBC) or muscle-invasive bladder cancer, TAR-200 is also being investigated in intermediate-risk NMIBC with gemcitabine (e.g., in the SunRISe-1 study).

This directly threatens UroGen's lead pipeline asset, UGN-102 (mitomycin in RTGel™), which is targeting low-grade intermediate-risk NMIBC. Both products aim to provide sustained local delivery of chemotherapy to the bladder, offering a non-surgical or minimally invasive treatment option for NMIBC. Given Johnson & Johnson's vast resources and experience in drug development and commercialization, a successful TAR-200 could capture significant market share in a patient population that UroGen is heavily banking on for future growth with UGN-102. This represents a direct competitive platform technology from a formidable industry player, analogous to how a new disruptive technology from a major competitor can challenge an existing or emerging market leader.

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UroGen Pharma's main products and pipeline candidates address the following markets:

  • UGN-102 (ZUSDURI) for low-grade intermediate-risk non-muscle invasive bladder cancer (LG-IR-NMIBC): The estimated market opportunity for UGN-102 is over $5 billion in the U.S.. This condition affects an estimated 82,000 patients annually in the U.S.. Another estimate indicates approximately 22,000 newly diagnosed patients annually in the U.S., with 60,000 recurrences each year.
  • JELMYTO (UGN-101/UGN-104) for low-grade upper tract urothelial carcinoma (LG-UTUC): The annual treatable patient population for LG-UTUC in the United States is approximately 6,000 to 7,000 individuals.

AI Analysis | Feedback

UroGen Pharma (URGN) is poised for future revenue growth over the next 2-3 years, driven by the expansion of its commercialized products and the progression of its pipeline. Key drivers include:

  1. Accelerated Adoption and Market Penetration of ZUSDURI (UGN-102): Following its FDA approval in June 2025 for recurrent low-grade intermediate-risk non-muscle invasive bladder cancer (LG-IR-NMIBC), ZUSDURI is expected to be a significant revenue driver. The implementation of a permanent J-code in January 2026 is anticipated to accelerate its adoption, particularly in community settings, by streamlining reimbursement processes and facilitating wider usage. UroGen Pharma projects ZUSDURI to achieve over $1 billion in peak annual revenue, addressing an estimated $5 billion annual market opportunity.

  2. Continued Growth of JELMYTO: JELMYTO (mitomycin) for pyelocalyceal solution, approved for low-grade upper tract urothelial cancer (LG-UTUC), continues to demonstrate strong underlying patient demand. The company anticipates JELMYTO net product revenues to be in the range of $94 million to $98 million for 2025, representing an expected 8%-12% year-over-year growth over 2024 demand-driven revenues.

  3. Launch of Next-Generation Pipeline Products (UGN-103 and UGN-104): UroGen Pharma is advancing its pipeline with next-generation therapies. An New Drug Application (NDA) for UGN-103, a next-generation product for recurrent LG-IR-NMIBC, is planned for submission in the second half of 2026, with potential approval anticipated in 2027. UGN-104, designed as a next-generation therapy for JELMYTO, is expected to follow approximately a year later.

  4. Expanded Commercial Infrastructure and Sales Force: To maximize the market reach and adoption of its products, particularly with the launch of ZUSDURI, UroGen Pharma has significantly expanded its commercial infrastructure. This includes increasing its sales force from 40 to 82 representatives and expanding to 130 customer-facing roles. These efforts are aimed at increasing prescriber awareness and securing broad reimbursement coverage.

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Share Issuance

  • In July 2023, UroGen Pharma announced a private placement of ordinary shares, expecting to receive gross proceeds of approximately $120 million. This involved the issuance of 12,579,156 ordinary shares at a purchase price of $9.54 per share.
  • In June 2024, the company raised approximately $116.2 million in net proceeds from a public offering to support the UGN-102 launch and for business development opportunities.
  • The number of ordinary shares outstanding significantly increased from 22.14 million at the end of 2020 to 47.73 million as of November 2025.

Inbound Investments

  • A private placement in July 2023, led by RA Capital Management L.P. and Great Point Partners LLC, secured approximately $120 million from selected institutional and accredited investors.
  • The company has a $125 million term loan facility with funds managed by Pharmakon Advisors, with interest expense related to this debt reported in 2024 and 2025.

Outbound Investments

  • In February 2025, UroGen expanded its nonclinical oncology portfolio through the purchase of product candidate UGN-501 from IconOVir Bio, Inc.

Capital Expenditures

  • Capital expenditures for UroGen Pharma were $1.22 million in 2020, $0.75 million in 2021, $0.25 million in 2022, $0.19 million in 2023, and $0.30 million in 2024.

Latest Trefis Analyses

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Trade Ideas

Select ideas related to URGN.

Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
QDEL_2282026_Insider_Buying_45D_2Buy_200K02282026QDELQuidelOrthoInsiderInsider Buys 45DStrong Insider Buying
Companies with multiple insider buys in the last 45 days
0.0%0.0%0.0%
CHE_2272026_Dip_Buyer_FCFYield02272026CHEChemedDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
0.0%0.0%0.0%
LLY_2272026_Monopoly_xInd_xCD_Getting_Cheaper02272026LLYEli LillyMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
0.0%0.0%0.0%
HAE_2202026_Dip_Buyer_FCFYield02202026HAEHaemoneticsDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
3.5%3.5%0.0%
IQV_2132026_Dip_Buyer_ValueBuy02132026IQVIQVIADip BuyDB | P/E OPMDip Buy with Low PE and High Margin
Buying dips for companies with tame PE and meaningfully high operating margin
7.1%7.1%-3.0%

Recent Active Movers

Peer Comparisons

Peers to compare with:

Financials

URGNCGONIBRXJNJMRKBMYMedian
NameUroGen P.CG Oncol.Immunity.Johnson .Merck Bristol-. 
Mkt Price18.8260.5510.00246.75119.8361.2260.88
Mkt Cap0.94.69.5594.1297.3124.567.0
Rev LTM9828394,19365,01148,19524,146
Op Inc LTM-110-180-26125,59622,10813,7236,807
FCF LTM--117-32519,31312,36012,84512,360
FCF 3Y Avg--76-38118,38313,20013,14613,146
CFO LTM--117-32024,53016,47214,15614,156
CFO 3Y Avg--76-36123,86216,98214,40214,402

Growth & Margins

URGNCGONIBRXJNJMRKBMYMedian
NameUroGen P.CG Oncol.Immunity.Johnson .Merck Bristol-. 
Rev Chg LTM14.7%217.8%1,026.0%6.0%1.3%-0.2%10.4%
Rev Chg 3Y Avg19.2%-748.2%2.6%3.2%1.5%3.2%
Rev Chg Q25.8%3,774.4%425.1%9.1%5.0%1.3%17.4%
QoQ Delta Rev Chg LTM6.1%294.6%45.9%2.2%1.2%0.3%4.2%
Op Mgn LTM-112.3%-8,285.3%-315.8%27.2%34.0%28.5%-42.6%
Op Mgn 3Y Avg-103.5%-14,894.4%-23,386.2%25.6%23.5%19.6%-41.9%
QoQ Delta Op Mgn LTM5.2%20,260.8%188.3%1.5%-0.9%4.7%5.0%
CFO/Rev LTM--5,372.2%-387.3%26.0%25.3%29.4%25.3%
CFO/Rev 3Y Avg--11,550.7%-22,561.1%26.7%26.8%30.5%26.7%
FCF/Rev LTM--5,387.7%-393.4%20.5%19.0%26.7%19.0%
FCF/Rev 3Y Avg--11,557.1%-25,112.6%20.6%20.8%27.9%20.6%

Valuation

URGNCGONIBRXJNJMRKBMYMedian
NameUroGen P.CG Oncol.Immunity.Johnson .Merck Bristol-. 
Mkt Cap0.94.69.5594.1297.3124.567.0
P/S9.32,137.1114.76.34.62.67.8
P/EBIT-7.4-25.8-38.117.713.311.11.9
P/E-6.5-30.7-27.222.216.317.74.9
P/CFO--39.8-29.624.218.08.88.8
Total Yield-15.3%-3.3%-3.7%6.6%8.9%9.7%1.7%
Dividend Yield0.0%0.0%0.0%2.1%2.8%4.1%1.0%
FCF Yield 3Y Avg---19.0%4.6%5.1%12.0%4.8%
D/E0.10.00.10.10.20.40.1
Net D/E0.0-0.10.00.00.10.30.0

Returns

URGNCGONIBRXJNJMRKBMYMedian
NameUroGen P.CG Oncol.Immunity.Johnson .Merck Bristol-. 
1M Rtn-4.0%16.3%60.0%9.2%8.7%11.2%10.2%
3M Rtn-22.8%46.4%378.5%20.8%19.6%28.4%24.6%
6M Rtn-3.6%120.5%320.2%40.2%42.8%32.5%41.5%
12M Rtn103.0%141.2%250.9%51.6%33.5%7.4%77.3%
3Y Rtn82.7%62.9%405.1%75.2%22.9%1.3%69.0%
1M Excs Rtn-2.3%18.1%61.8%10.9%10.4%13.0%11.9%
3M Excs Rtn-34.2%35.5%324.2%20.4%15.8%26.4%23.4%
6M Excs Rtn-8.8%120.2%321.8%35.4%39.6%27.6%37.5%
12M Excs Rtn84.5%119.7%189.5%39.2%20.3%-6.6%61.8%
3Y Excs Rtn22.5%-8.8%214.4%1.3%-52.2%-71.7%-3.8%

Comparison Analyses

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FDA Approved Drugs Data

Expand for More
Post-Approval Fwd Returns
FDA
App #
Brand
Name
Generic
Name
Dosage
Form
FDA
Approval
3M
Rtn
6M
Rtn
1Y
Rtn
2Y
Rtn
Total
Rtn
NDA215793  ZUSDURImitomycinpowder612202573.7%101.8%71.7%71.7%71.7%
NDA211728  JELMYTOmitomycinpowder415202015.8%7.5%-13.7%-62.8%-9.6%

Financials

Segment Financials

Revenue by Segment
$ Mil20242023202220212020
Jelmyto83644812 
Single Segment    0
Total836448120


Price Behavior

Price Behavior
Market Price$18.82 
Market Cap ($ Bil)0.9 
First Trading Date05/04/2017 
Distance from 52W High-36.0% 
   50 Days200 Days
DMA Price$21.21$18.29
DMA Trendupdown
Distance from DMA-11.3%2.9%
 3M1YR
Volatility59.3%114.0%
Downside Capture147.28131.63
Upside Capture-19.09183.00
Correlation (SPY)7.5%17.5%
URGN Betas & Captures as of 2/28/2026

 1M2M3M6M1Y3Y
Beta1.290.490.500.791.030.95
Up Beta0.890.091.592.430.530.57
Down Beta0.10-1.31-0.43-0.680.951.21
Up Capture211%117%-30%107%328%158%
Bmk +ve Days9203170142431
Stock +ve Days9182659125347
Down Capture140%169%147%93%115%102%
Bmk -ve Days12213054109320
Stock -ve Days12223464122394

[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with URGN
URGN91.6%113.9%1.10-
Sector ETF (XLV)6.7%17.4%0.2225.6%
Equity (SPY)15.6%19.3%0.6317.7%
Gold (GLD)79.3%26.1%2.222.7%
Commodities (DBC)17.8%17.1%0.805.2%
Real Estate (VNQ)5.6%16.6%0.1616.5%
Bitcoin (BTCUSD)-18.7%45.2%-0.320.9%

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Based On 5-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with URGN
URGN-3.3%91.7%0.34-
Sector ETF (XLV)8.1%14.5%0.3717.3%
Equity (SPY)13.2%17.0%0.6116.6%
Gold (GLD)22.8%17.3%1.08-1.1%
Commodities (DBC)10.8%19.0%0.460.2%
Real Estate (VNQ)4.8%18.8%0.1611.0%
Bitcoin (BTCUSD)6.7%56.8%0.346.4%

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Based On 10-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with URGN
URGN2.6%80.0%0.37-
Sector ETF (XLV)10.8%16.5%0.5423.0%
Equity (SPY)15.3%17.9%0.7424.0%
Gold (GLD)14.9%15.6%0.802.3%
Commodities (DBC)9.1%17.6%0.437.5%
Real Estate (VNQ)6.5%20.7%0.2817.7%
Bitcoin (BTCUSD)66.5%66.8%1.069.4%

Smart multi-asset allocation framework can stack odds in your favor. Learn How

Short Interest

Short Interest: As Of Date2132026
Short Interest: Shares Quantity9.3 Mil
Short Interest: % Change Since 1312026-9.4%
Average Daily Volume0.6 Mil
Days-to-Cover Short Interest15.1 days
Basic Shares Quantity48.1 Mil
Short % of Basic Shares19.4%

Earnings Returns History

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 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
3/2/2026-12.4%  
11/6/202521.9%30.2%19.5%
8/7/2025-7.1%0.5%-5.6%
3/10/20251.0%12.7%1.4%
11/6/20240.2%1.1%0.0%
8/13/20243.1%1.4%-4.8%
3/14/2024-18.0%-14.4%-13.6%
11/14/2023-0.7%5.7%35.5%
...
SUMMARY STATS   
# Positive1096
# Negative8811
Median Positive2.6%4.0%10.9%
Median Negative-9.9%-5.9%-13.6%
Max Positive21.9%30.2%35.5%
Max Negative-22.9%-37.0%-48.1%

SEC Filings

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Report DateFiling DateFiling
09/30/202511/06/202510-Q
03/31/202505/12/202510-Q
12/31/202403/10/202510-K
09/30/202411/06/202410-Q
06/30/202408/13/202410-Q
03/31/202405/13/202410-Q
12/31/202303/14/202410-K
09/30/202311/14/202310-Q
06/30/202308/10/202310-Q
03/31/202305/11/202310-Q
12/31/202203/24/202310-K
09/30/202211/10/202210-Q
06/30/202208/11/202210-Q
03/31/202205/10/202210-Q
12/31/202103/21/202210-K
09/30/202111/15/202110-Q

Insider Activity

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#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Schoenberg, MarkChief Medical OfficerDirectSell1120202525.0010,000250,0003,475,625Form
2Degnan, ChrisChief Financial OfficerDirectSell1009202516.852,20337,12138,418Form
3Schoenberg, MarkChief Medical OfficerDirectSell909202519.1187116,6452,847,868Form
4Smith, Jason DrewGeneral CounselDirectSell909202519.111,52029,047827,559Form
5Schoenberg, MarkChief Medical OfficerDirectSell813202517.6910,000176,9002,622,171Form