Tearsheet

Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.

0

Megatrend and thematic drivers
Megatrends include Precision Medicine, and Aging Population & Chronic Disease. Themes include Targeted Therapies, Biopharmaceutical R&D, Show more.

Trading close to highs
Dist 52W High is 0.0%, Dist 3Y High is 0.0%

Meaningful short interest
Short Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 13%

Very low revenue
Rev LTMTotal Revenue or Sales, Last Twelve Months is 0

Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -410 Mil

Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -9.7%

Significant short interest
Short Interest Days-to-CoverDTC = (Short Interest Share Quantity) / (Average Daily Trading Volume). Reflects how many days it would take to cover (close out) the short interest based on average volumes. High DTC can signify an increased risk of a short squeeze. is 16.16

Key risks
SRRK key risks include [1] manufacturing and regulatory delays for its lead asset, Show more.

0 Megatrend and thematic drivers
Megatrends include Precision Medicine, and Aging Population & Chronic Disease. Themes include Targeted Therapies, Biopharmaceutical R&D, Show more.
1 Trading close to highs
Dist 52W High is 0.0%, Dist 3Y High is 0.0%
2 Meaningful short interest
Short Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 13%
3 Very low revenue
Rev LTMTotal Revenue or Sales, Last Twelve Months is 0
4 Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -410 Mil
5 Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -9.7%
6 Significant short interest
Short Interest Days-to-CoverDTC = (Short Interest Share Quantity) / (Average Daily Trading Volume). Reflects how many days it would take to cover (close out) the short interest based on average volumes. High DTC can signify an increased risk of a short squeeze. is 16.16
7 Key risks
SRRK key risks include [1] manufacturing and regulatory delays for its lead asset, Show more.

SRRK in ETFs

Weight = SRRK's share of each fund

VTI0.01%
ITOT0.01%
IWM0.18%
VB0.00%
XBI1.1%
IBB0.40%
IWO0.35%
VTWO0.12%
+7 more covered ETFs

Valuation & Metrics

Price Chart

Why The Stock Moved

Qualitative Assessment

AI Analysis | Feedback

Updated on 7/9/2026

Scholar Rock (SRRK) stock has gained about 20% since 3/31/2026 because of the following key factors:

1. Significant Regulatory Progress for Apitegromab in Spinal Muscular Atrophy (SMA).

Scholar Rock announced the FDA's acceptance of its Biologics License Application (BLA) for apitegromab on May 7, 2026, for the treatment of SMA. This followed encouraging engagement with the FDA regarding manufacturing facility remediation and reinforced the anticipated U.S. commercial launch in 2026, de-risking the company's lead product. Additionally, a Committee for Medicinal Products for Human Use (CHMP) opinion for the apitegromab Marketing Authorisation Application (MAA) was expected near mid-2026, preceding a planned European launch in the second half of 2026, beginning with Germany.

2. Advancement of the Clinical Pipeline.

The company demonstrated continued pipeline progress with the expected initiation of the Phase 2 FORGE trial for apitegromab in Facioscapulohumeral Muscular Dystrophy (FSHD) in mid-2026. Furthermore, a Phase 1 study for SRK-439, a novel subcutaneously administered myostatin inhibitor, was underway in healthy volunteers, with topline data anticipated in the second half of 2026. These developments highlight future growth opportunities beyond SMA.

Show more
Updated on 7/9/2026

Scholar Rock (SRRK) stock has gained about 20% since 3/31/2026 because of the following key factors:

1. Significant Regulatory Progress for Apitegromab in Spinal Muscular Atrophy (SMA).

Scholar Rock announced the FDA's acceptance of its Biologics License Application (BLA) for apitegromab on May 7, 2026, for the treatment of SMA. This followed encouraging engagement with the FDA regarding manufacturing facility remediation and reinforced the anticipated U.S. commercial launch in 2026, de-risking the company's lead product. Additionally, a Committee for Medicinal Products for Human Use (CHMP) opinion for the apitegromab Marketing Authorisation Application (MAA) was expected near mid-2026, preceding a planned European launch in the second half of 2026, beginning with Germany.

2. Advancement of the Clinical Pipeline.

The company demonstrated continued pipeline progress with the expected initiation of the Phase 2 FORGE trial for apitegromab in Facioscapulohumeral Muscular Dystrophy (FSHD) in mid-2026. Furthermore, a Phase 1 study for SRK-439, a novel subcutaneously administered myostatin inhibitor, was underway in healthy volunteers, with topline data anticipated in the second half of 2026. These developments highlight future growth opportunities beyond SMA.

3. Strong Analyst Confidence and Positive Market Sentiment.

During the period, multiple analyst firms reiterated "Buy" ratings and increased price targets for Scholar Rock. For instance, as of June 18, 2026, 18 analysts polled by S&P Global assigned SRRK a consensus "Strong Buy" rating with an average price target of $59.31, indicating a 12.24% upside from the stock price at that time. This robust analyst sentiment reflected growing confidence in the company's clinical milestones and commercial prospects.

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Stock Movement Drivers

Fundamental Drivers

The 17.9% change in SRRK stock from 3/31/2026 to 7/9/2026 was primarily driven by a 0.0% change in the company's Total Revenues ($ Mil).
(LTM values as of)33120267092026Change
Stock Price ($)49.1657.9417.9%
Change Contribution By: 
Total Revenues ($ Mil)000.0%
P/S Multiple0.0%
Shares Outstanding (Mil)121127-5.3%
Cumulative Contribution0.0%

LTM = Last Twelve Months as of date shown

Market Drivers

3/31/2026 to 7/9/2026
ReturnCorrelation
SRRK17.9% 
Market (SPY)15.6%13.3%
Sector (XLV)10.6%26.5%

Fundamental Drivers

The 31.5% change in SRRK stock from 12/31/2025 to 7/9/2026 was primarily driven by a 0.0% change in the company's Total Revenues ($ Mil).
(LTM values as of)123120257092026Change
Stock Price ($)44.0557.9431.5%
Change Contribution By: 
Total Revenues ($ Mil)000.0%
P/S Multiple0.0%
Shares Outstanding (Mil)114127-10.6%
Cumulative Contribution0.0%

LTM = Last Twelve Months as of date shown

Market Drivers

12/31/2025 to 7/9/2026
ReturnCorrelation
SRRK31.5% 
Market (SPY)10.5%32.0%
Sector (XLV)5.2%29.9%

Fundamental Drivers

The 63.6% change in SRRK stock from 6/30/2025 to 7/9/2026 was primarily driven by a 0.0% change in the company's Total Revenues ($ Mil).
(LTM values as of)63020257092026Change
Stock Price ($)35.4257.9463.6%
Change Contribution By: 
Total Revenues ($ Mil)000.0%
P/S Multiple0.0%
Shares Outstanding (Mil)112127-12.1%
Cumulative Contribution0.0%

LTM = Last Twelve Months as of date shown

Market Drivers

6/30/2025 to 7/9/2026
ReturnCorrelation
SRRK63.6% 
Market (SPY)22.7%22.6%
Sector (XLV)21.9%18.1%

Fundamental Drivers

The 668.4% change in SRRK stock from 6/30/2023 to 7/9/2026 was primarily driven by a 0.0% change in the company's Total Revenues ($ Mil).
(LTM values as of)63020237092026Change
Stock Price ($)7.5457.94668.4%
Change Contribution By: 
Total Revenues ($ Mil)000.0%
P/S Multiple0.0%
Shares Outstanding (Mil)80127-37.5%
Cumulative Contribution0.0%

LTM = Last Twelve Months as of date shown

Market Drivers

6/30/2023 to 7/9/2026
ReturnCorrelation
SRRK668.4% 
Market (SPY)75.6%5.4%
Sector (XLV)27.9%6.2%

Return vs. Risk

Price Returns Compared

 202120222023202420252026Total [1]
Returns
SRRK Return-49%-64%108%130%2%27%15%
Peers Return-20%19%-1%-0%27%3%24%
S&P 500 Return27%-19%24%23%16%9%99%

Monthly Win Rates [3]
SRRK Win Rate42%42%50%58%42%71% 
Peers Win Rate47%58%48%47%52%51% 
S&P 500 Win Rate75%42%67%75%67%43% 

Max Drawdowns [4]
SRRK Max Drawdown-65%-81%-54%-62%-48%-17% 
Peers Max Drawdown-47%-30%-38%-37%-43%-23% 
S&P 500 Max Drawdown-5%-25%-10%-8%-19%-9% 


[1] Cumulative total returns since the beginning of 2021
[2] Peers: BIIB, IONS, SRPT, PTCT, REGN. See SRRK Returns vs. Peers.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 7/9/2026 (YTD)

How Low Can It Go

EventSRRKS&P 500
2025 US Tariff Shock
  % Loss-35.6%-18.8%
  % Gain to Breakeven55.3%23.1%
  Time to Breakeven93 days79 days
2023 SVB Regional Banking Crisis
  % Loss-42.1%-6.7%
  % Gain to Breakeven72.7%7.1%
  Time to Breakeven149 days31 days
2022 Inflation Shock & Fed Tightening
  % Loss-81.1%-24.5%
  % Gain to Breakeven429.6%32.4%
  Time to Breakeven859 days427 days
2020 COVID-19 Crash
  % Loss-27.4%-33.7%
  % Gain to Breakeven37.7%50.9%
  Time to Breakeven2 days140 days
Q4 2018 Fed Policy Error / Growth Scare
  % Loss-32.7%-19.2%
  % Gain to Breakeven48.6%23.8%
  Time to Breakeven651 days105 days

Compare to BIIB, IONS, SRPT, PTCT, REGN

In The Past

Scholar Rock's stock fell -35.6% during the 2025 US Tariff Shock. Such a loss loss requires a 55.3% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

EventSRRKS&P 500
2025 US Tariff Shock
  % Loss-35.6%-18.8%
  % Gain to Breakeven55.3%23.1%
  Time to Breakeven93 days79 days
2023 SVB Regional Banking Crisis
  % Loss-42.1%-6.7%
  % Gain to Breakeven72.7%7.1%
  Time to Breakeven149 days31 days
2022 Inflation Shock & Fed Tightening
  % Loss-81.1%-24.5%
  % Gain to Breakeven429.6%32.4%
  Time to Breakeven859 days427 days
2020 COVID-19 Crash
  % Loss-27.4%-33.7%
  % Gain to Breakeven37.7%50.9%
  Time to Breakeven2 days140 days
Q4 2018 Fed Policy Error / Growth Scare
  % Loss-32.7%-19.2%
  % Gain to Breakeven48.6%23.8%
  Time to Breakeven651 days105 days

Compare to BIIB, IONS, SRPT, PTCT, REGN

In The Past

Scholar Rock's stock fell -35.6% during the 2025 US Tariff Shock. Such a loss loss requires a 55.3% gain to breakeven.

Preserve Wealth

Limiting losses and compounding gains is essential to preserving wealth.

Asset Allocation

Actively managed asset allocation strategies protect wealth. Learn more.

About Scholar Rock (SRRK)

Scholar Rock (SRRK) is a biopharmaceutical company focused on discovering and developing novel medicines for serious diseases where protein growth factor signaling is a key factor. The company aims to address unmet medical needs in areas such as neuromuscular disorders, various cancers, and fibrotic diseases by targeting these specific biological pathways with innovative therapeutic candidates.

The company's lead product candidate, Apitegromab, has completed Phase 3 clinical trials and is being developed for the treatment of Spinal Muscular Atrophy (SMA). Additionally, Scholar Rock is advancing SRK-181 through Phase 1 clinical trials, which targets cancers that have become resistant to existing checkpoint inhibitor therapies, such as anti-PD-1 treatments. The company also maintains a broader pipeline of product candidates and has a strategic collaboration with Gilead Sciences, Inc. to discover and develop specific inhibitors for transforming growth factor beta activation, intended for fibrotic diseases.

AI Analysis | Feedback

1. An early-stage Vertex Pharmaceuticals focused on rare neuromuscular disorders.

2. A developing biotech similar to Biogen, with drugs for neurological diseases, cancer, and fibrosis.

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Scholar Rock's major products are experimental drug candidates in various stages of clinical development:

  • Apitegromab: An inhibitor designed to treat spinal muscular atrophy, having completed Phase 3 clinical trials.
  • SRK-181: A drug candidate in Phase 1 clinical trials targeting cancers resistant to checkpoint inhibitor therapies.
  • Novel product candidates: A pipeline of developing therapies aimed at neuromuscular disorders, cancer, and fibrosis.
  • TGFβ inhibitors: Specific inhibitors of transforming growth factor beta activation being discovered and developed in collaboration with Gilead Sciences for fibrotic diseases.

AI Analysis | Feedback

Scholar Rock (SRRK) is a biopharmaceutical company focused on the discovery and development of medicines. Given its stage of development, with drug candidates primarily in clinical trials, it does not currently have major customers in the traditional sense of selling finished products directly to individuals or end-users.

Instead, its revenue or strategic relationships typically come from collaborations or partnerships with larger pharmaceutical companies that license, co-develop, or acquire its drug candidates. Based on the provided description, the company sells primarily to other companies in this context.

The major customer or strategic partner explicitly mentioned in the background information is:

  • Gilead Sciences, Inc. (GILD)

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David Hallal
Chief Executive Officer & Chairman

David Hallal was appointed Chief Executive Officer in April 2025 and has served as Chairman of Scholar Rock's Board of Directors since 2017. Prior to joining Scholar Rock, he spent over a decade as CEO, COO, and CCO of Alexion, where he was responsible for building and leading the company's 50-country operating platform.

Vikas Sinha
Chief Financial Officer

Vikas Sinha was appointed Chief Financial Officer in April 2025. He previously held the position of Chief Financial Officer at Alexion and ElevateBio.

Akshay Vaishnaw M.D., Ph.D.
President, R&D

Akshay Vaishnaw was appointed to the newly created role of President of Research & Development in April 2025. He has been a member of Scholar Rock's Board of Directors since 2019 and previously served as President of Alnylam.

R. Keith Woods
Chief Operating Officer

R. Keith Woods was appointed to the newly created role of Chief Operating Officer in April 2025, with a focus on evolving the organization into a fully integrated global commercial enterprise. He was formerly the Chief Operating Officer of argenx.

Lisa Wyman
Chief Technical and Quality Officer

Lisa Wyman was appointed Chief Technical and Quality Officer in January 2025. She brings over 20 years of leadership and functional experience in technical and quality operations, including executive team responsibilities at Generate:Biomedicines and Acceleron Pharma. Acceleron Pharma was acquired by Merck in 2021.

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Key Risks for Scholar Rock (SRRK)

  1. Regulatory approval and commercial success of lead product candidates: Scholar Rock's future revenue and profitability are heavily dependent on the successful regulatory approval and subsequent commercialization of its lead product candidate, Apitegromab, which has completed Phase 3 clinical trials for spinal muscular atrophy. There is no guarantee that Apitegromab will receive regulatory approval or achieve significant market acceptance, which would severely impact the company's business and financial prospects. Similarly, the success of other pipeline candidates, such as SRK-181 (in Phase 1 clinical trials), is critical but also uncertain.
  2. Reliance on a limited number of product candidates: The company's business model is significantly concentrated around the successful development and commercialization of a small number of product candidates, primarily Apitegromab and SRK-181. A setback, failure in clinical trials, or adverse regulatory decision for either of these key programs could have a disproportionately negative impact on Scholar Rock's financial condition and ability to continue operations.

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Apitegromab (Spinal Muscular Atrophy)

The addressable market for Apitegromab in the treatment of spinal muscular atrophy (SMA) is substantial. In the U.S. market, Apitegromab's revenue is projected to reach an annual total of $433 million by 2037. Globally, the spinal muscular atrophy treatment market size was estimated at USD 4.40 billion in 2024 and is projected to reach USD 13.09 billion by 2030, growing at a CAGR of 18.0% from 2025 to 2030. Another source projects the global spinal muscular atrophy therapeutics market to rise from USD 6.06 billion in 2026 to USD 13.48 billion by 2031. Scholar Rock plans to launch apitegromab commercially in the US and Europe in 2026 and aims to expand its market reach to 50 countries, targeting 35,000 SMA patients. Analyst estimates indicate peak sales for Apitegromab could reach $1.5 billion.

SRK-181 (Cancers Resistant to Checkpoint Inhibitor Therapies)

SRK-181 targets cancers that are resistant to checkpoint inhibitor therapies, such as anti-PD-1 or anti-PD-L1 antibody therapies. The global market for checkpoint inhibitor refractory cancer drugs was estimated at USD 42,632.94 million in 2025 and is expected to grow to USD 95,548.35 million by 2032, at a Compound Annual Growth Rate (CAGR) of 12.67% from 2025 to 2032. This market encompasses the expanding patient pool that does not respond to, or progresses after, PD-(L)1 and CTLA-4 checkpoint inhibitor therapy.

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Expected Drivers of Future Revenue Growth for Scholar Rock (SRRK)

Over the next 2-3 years, Scholar Rock Holding Corporation's future revenue growth is primarily anticipated to be driven by the following key factors:

  1. U.S. Commercial Launch and Ramp-up of Apitegromab for Spinal Muscular Atrophy (SMA): Scholar Rock is preparing for the U.S. commercial launch of apitegromab in 2026, following a constructive meeting with the FDA and progress in addressing manufacturing facility observations. This therapy aims to be the first muscle-targeted treatment approved for both children and adults with SMA.
  2. European Commercial Launch and Expansion of Apitegromab for SMA: Following the anticipated U.S. launch, a regulatory decision from the European Medicines Agency (EMA) is expected by mid-2026, with a European launch projected for the second half of 2026, starting with Germany. This will open up significant international market access for apitegromab.
  3. Global Market Expansion of Apitegromab: Beyond the initial U.S. and European markets, Scholar Rock plans to establish a 50-country operating platform, targeting a broad patient population of approximately 35,000 SMA patients, with a focus on expansion into regions like Asia-Pacific and Latin America.
  4. Advancement of Apitegromab into Additional Indications and Formulations: The company is actively pursuing the expansion of apitegromab's market potential through further clinical development. This includes the Phase 2 OPAL study evaluating apitegromab in combination with gene therapy for infants and toddlers under two years old with SMA. Additionally, Scholar Rock is exploring the development of a subcutaneous version of apitegromab, which could broaden its administration options and patient reach following the approval of the intravenous formulation.

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Share Issuance

  • Scholar Rock completed an upsized public offering of common stock and pre-funded warrants in October 2024, generating approximately $300 million in gross proceeds to support commercialization, advance clinical programs, and for general corporate purposes.
  • The company reported $60.4 million from warrant exercises in the fourth quarter of 2025, contributing to its cash balance.

Inbound Investments

  • Scholar Rock secured a new debt facility of up to $550 million with Blue Owl Capital, with an additional $100 million expected to be drawn by the end of the first quarter of 2026, to support commercial and pipeline initiatives.
  • The company anticipates monetizing a rare pediatric disease priority review voucher, potentially valued between $150 million and $200 million, upon apitegromab approval.

Capital Expenditures

  • Annual capital expenditures were $5.25 million in 2021, $1.06 million in 2022, $0.06 million in 2023, $0.10 million in 2024, and $0.60 million in 2025.
  • Current and planned capital expenditures are focused on commercial readiness and inventory build-out for apitegromab, advancing clinical programs, and developing its technology platform.
  • The company is investing in a second U.S. fill-finish facility to strengthen supply continuity and support future commercial demand for apitegromab.

Recent Active Movers

Peer Comparisons

Peers to compare with:

Financials

SRRKBIIBIONSSRPTPTCTREGNMedian
NameScholar .Biogen Ionis Ph.Sarepta .PTC Ther.Regenero. 
Mkt Price57.94198.9164.2720.5289.55667.9576.91
Mkt Cap7.429.310.62.27.469.59.0
Rev LTM09,9371,0582,18482714,9201,621
Op Inc LTM-4102,304-3521-673,843-33
FCF LTM-3042,316-978108-5173,791-98
FCF 3Y Avg-2291,965-629-414-153,561-122
CFO LTM-3032,591-911175-2185,013-21
CFO 3Y Avg-2282,272-579-3021394,568-45

Growth & Margins

SRRKBIIBIONSSRPTPTCTREGNMedian
NameScholar .Biogen Ionis Ph.Sarepta .PTC Ther.Regenero. 
Rev Chg LTM-1.2%47.5%-2.2%-53.3%5.9%1.2%
Rev Chg 3Y Avg--0.5%24.9%33.6%19.4%6.4%19.4%
Rev Chg Q-1.9%87.0%-1.9%-76.8%19.0%1.9%
QoQ Delta Rev Chg LTM-0.5%12.1%-0.6%-52.2%4.0%0.5%
Op Inc Chg LTM-51.3%-1.1%25.4%100.9%-107.7%-2.4%-1.7%
Op Inc Chg 3Y Avg-35.7%-3.4%6.9%53.7%113.8%-6.3%1.7%
Op Mgn LTM-23.2%-33.3%0.0%-8.1%25.8%0.0%
Op Mgn 3Y Avg-22.2%-49.8%-4.0%3.6%28.1%3.6%
QoQ Delta Op Mgn LTM--1.8%7.2%30.0%-57.6%-0.1%-0.1%
CFO/Rev LTM-26.1%-86.1%8.0%-26.4%33.6%8.0%
CFO/Rev 3Y Avg-23.1%-65.9%-18.2%2.1%32.6%2.1%
FCF/Rev LTM-23.3%-92.4%5.0%-62.5%25.4%5.0%
FCF/Rev 3Y Avg-20.0%-71.8%-24.3%-15.4%25.5%-15.4%

Valuation

SRRKBIIBIONSSRPTPTCTREGNMedian
NameScholar .Biogen Ionis Ph.Sarepta .PTC Ther.Regenero. 
Mkt Cap7.429.310.62.27.469.59.0
P/S-2.910.01.08.94.74.7
P/Op Inc-18.012.7-30.12,057.6-110.118.1-2.6
P/EBIT-18.415.4-43.827.0-107.913.3-2.5
P/E-18.021.3-32.433.1-39.615.7-1.2
P/CFO-24.311.3-11.612.3-33.913.9-0.2
Total Yield-5.5%4.7%-3.1%3.0%-2.5%6.9%0.2%
Dividend Yield0.0%0.0%0.0%0.0%0.0%0.5%0.0%
FCF Yield 3Y Avg-6.7%8.1%-8.4%-4.0%-0.4%4.3%-2.2%
D/E0.00.20.20.50.10.00.1
Net D/E-0.00.10.00.2-0.2-0.1-0.0

Returns

SRRKBIIBIONSSRPTPTCTREGNMedian
NameScholar .Biogen Ionis Ph.Sarepta .PTC Ther.Regenero. 
1M Rtn27.1%-0.1%-13.8%29.1%21.5%8.4%15.0%
3M Rtn17.8%12.3%-15.9%-7.7%26.4%-12.9%2.3%
6M Rtn39.0%6.9%-21.2%-11.4%16.5%-16.4%-2.2%
12M Rtn56.6%49.5%50.1%5.9%83.7%21.5%49.8%
3Y Rtn688.3%-29.4%53.8%-81.3%122.4%-4.3%24.8%
1M Excs Rtn30.4%1.4%-14.5%30.1%24.5%7.4%15.9%
3M Excs Rtn4.7%-0.7%-25.5%-17.5%14.4%-25.0%-9.1%
6M Excs Rtn31.6%0.3%-29.8%-16.8%8.1%-22.4%-8.3%
12M Excs Rtn48.0%26.8%34.3%-13.3%66.8%1.4%30.5%
3Y Excs Rtn614.7%-99.6%-12.9%-151.2%46.9%-75.5%-44.2%

Financials

Segment Financials

Revenue by Segment
$ Mil20232022202120202019
Single Segment033191520
Total033191520


Net Income by Segment
$ Mil2025
Single Segment-378
Total-378


Assets by Segment
$ Mil20242023202220212018
Single Segment475311358304181
Total475311358304181


Price Behavior

Price Behavior
Market Price$57.94 
Market Cap ($ Bil)7.4 
First Trading Date05/24/2018 
Distance from 52W High0.0% 
   50 Days200 Days
DMA Price$48.48$43.43
DMA Trendupup
Distance from DMA19.5%33.4%
 3M1YR
Volatility38.8%62.4%
Downside Capture-17.8576.40
Upside Capture53.87111.86
Correlation (SPY)14.4%22.3%
SRRK Betas & Captures as of 6/30/2026

 1M2M3M6M1Y3Y
Beta0.290.670.991.191.120.78
Up Beta2.302.072.412.471.511.23
Down Beta1.870.720.430.980.990.96
Up Capture-16%78%70%93%132%178%
Bmk +ve Days11244067140429
Stock +ve Days13233563125369
Down Capture-143%-32%-13%68%94%82%
Bmk -ve Days10172358112321
Stock -ve Days8182862125376

[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with SRRK
SRRK69.6%62.8%1.07-
Sector ETF (XLV)21.8%15.7%1.0619.7%
Equity (SPY)22.3%12.5%1.3322.4%
Gold (GLD)24.4%27.8%0.773.5%
Commodities (DBC)23.6%18.7%1.00-5.5%
Real Estate (VNQ)13.2%13.9%0.6515.0%
Bitcoin (BTCUSD)-42.8%42.8%-1.1815.1%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 5-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with SRRK
SRRK15.0%180.0%0.46-
Sector ETF (XLV)6.8%14.9%0.279.2%
Equity (SPY)13.4%17.1%0.619.9%
Gold (GLD)18.0%18.3%0.80-0.2%
Commodities (DBC)7.5%19.5%0.283.1%
Real Estate (VNQ)2.9%18.9%0.068.9%
Bitcoin (BTCUSD)12.3%53.5%0.427.4%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 10-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with SRRK
SRRK14.1%157.0%0.49-
Sector ETF (XLV)10.6%16.6%0.5210.1%
Equity (SPY)15.8%17.9%0.7510.7%
Gold (GLD)11.7%16.1%0.59-0.1%
Commodities (DBC)6.1%18.0%0.274.6%
Real Estate (VNQ)5.2%20.7%0.226.9%
Bitcoin (BTCUSD)58.0%66.2%0.984.4%

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Short Interest

Short Interest: As Of Date6152026
Short Interest: Shares Quantity16.7 Mil
Short Interest: % Change Since 53120261.8%
Average Daily Volume1.0 Mil
Days-to-Cover Short Interest16.2 days
Basic Shares Quantity127.3 Mil
Short % of Basic Shares13.1%

Earnings Returns History

Updated 6/10/2026
Expand for More
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
5/7/2026-1.4%6.5%-6.0%
3/3/20261.9%1.7%13.1%
1/12/20263.3%6.6%12.9%
11/14/202524.4%26.4%47.4%
8/6/2025-6.4%-12.9%-12.3%
5/14/2025-2.7%0.4%6.1%
2/27/2025-2.9%-2.4%-9.9%
11/12/2024-5.3%-6.3%49.8%
...
SUMMARY STATS   
# Positive171713
# Negative9913
Median Positive5.8%6.6%9.6%
Median Negative-2.5%-6.3%-9.9%
Max Positive24.4%32.5%49.8%
Max Negative-6.4%-18.8%-44.6%
Collapse to Preview
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
5/7/2026-1.4%6.5%-6.0%
3/3/20261.9%1.7%13.1%
1/12/20263.3%6.6%12.9%
11/14/202524.4%26.4%47.4%
8/6/2025-6.4%-12.9%-12.3%
5/14/2025-2.7%0.4%6.1%
2/27/2025-2.9%-2.4%-9.9%
11/12/2024-5.3%-6.3%49.8%
8/8/2024-1.0%11.6%-2.7%
5/7/2024-2.5%-9.4%-34.7%
3/19/202414.8%21.3%3.8%
1/8/20245.8%1.2%-1.1%
11/7/20231.5%-18.8%30.9%
8/9/202311.3%9.0%1.0%
5/9/20236.0%3.7%-15.8%
3/7/20236.6%2.3%-13.2%
11/14/20221.1%0.2%-0.9%
8/8/20226.7%32.5%4.9%
5/16/202215.0%-0.6%-3.3%
3/7/20223.7%-9.5%-9.9%
11/9/20213.8%24.1%-8.2%
8/10/20213.5%12.1%3.3%
5/13/2021-0.5%-3.9%10.6%
3/9/20218.3%15.8%-44.6%
11/9/2020-0.5%2.8%9.6%
8/7/20202.3%-0.2%5.0%
SUMMARY STATS   
# Positive171713
# Negative9913
Median Positive5.8%6.6%9.6%
Median Negative-2.5%-6.3%-9.9%
Max Positive24.4%32.5%49.8%
Max Negative-6.4%-18.8%-44.6%

SEC Filings

Expand for More
Report DateFiling DateFiling
03/31/202605/07/202610-Q
12/31/202503/03/202610-K
09/30/202511/14/202510-Q
06/30/202508/06/202510-Q
03/31/202505/14/202510-Q
12/31/202402/27/202510-K
09/30/202411/12/202410-Q
06/30/202408/08/202410-Q
03/31/202405/07/202410-Q
12/31/202303/19/202410-K
09/30/202311/07/202310-Q
06/30/202308/09/202310-Q
03/31/202305/09/202310-Q
12/31/202203/07/202310-K
09/30/202211/14/202210-Q
06/30/202208/08/202210-Q
Collapse to Preview
Report DateFiling DateFiling
03/31/202605/07/202610-Q
12/31/202503/03/202610-K
09/30/202511/14/202510-Q
06/30/202508/06/202510-Q
03/31/202505/14/202510-Q
12/31/202402/27/202510-K
09/30/202411/12/202410-Q
06/30/202408/08/202410-Q
03/31/202405/07/202410-Q
12/31/202303/19/202410-K
09/30/202311/07/202310-Q
06/30/202308/09/202310-Q
03/31/202305/09/202310-Q
12/31/202203/07/202310-K
09/30/202211/14/202210-Q
06/30/202208/08/202210-Q
03/31/202205/16/202210-Q
12/31/202103/07/202210-K
09/30/202111/09/202110-Q
06/30/202108/10/202110-Q
03/31/202105/13/202110-Q
12/31/202003/09/202110-K
09/30/202011/09/202010-Q
06/30/202008/07/202010-Q
03/31/202005/07/202010-Q
12/31/201903/12/202010-K
09/30/201911/12/201910-Q
06/30/201908/14/201910-Q

Recent Forward Guidance

Updated 7/8/2026

Latest: Q1 2026 Earnings Reported 5/7/2026

Forward GuidanceGuidance Change
MetricLowMidHigh% Chg% DeltaChangePrior
Q3 2026 Commercial Supply Availability      
2026 Phase 2 FORGE Trial Initiation      
2026 SRK-439 Topline Data      

Prior: Q4 2025 Earnings Reported 3/3/2026

Forward GuidanceGuidance Change
MetricLowMidHigh% Chg% DeltaChangePrior
Q1 2026 Debt Facility Drawdown 100.00 Mil    
2026 Debt Facility Availability 150.00 Mil    

Q4 2025 Earnings Reported 1/12/2026

Forward GuidanceGuidance Change
MetricLowMidHigh% Chg% DeltaChangePrior
2027 Cash Runway 2,027    

Q3 2025 Earnings Reported 11/14/2025

Forward GuidanceGuidance Change
MetricLowMidHigh% Chg% DeltaChangePrior
2025 Cash from warrants 60.00 Mil    

Insider Activity

Updated 7/6/2026
Expand for More
#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Flier, Jeffrey S DirectSell706202653.883,053164,4901,500,832Form
2Burow, Kristina DirectSell706202653.743,053164,0646,161,502Form
3Reed, Joshua DirectSell706202653.743,053164,0671,048,892Form
4Peng, Katie DirectSell706202653.885,446293,4051,847,974Form
5Gilman, Michael DirectSell706202653.872,544137,0583,206,154Form
Collapse to Preview
#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Flier, Jeffrey S DirectSell706202653.883,053164,4901,500,832Form
2Burow, Kristina DirectSell706202653.743,053164,0646,161,502Form
3Reed, Joshua DirectSell706202653.743,053164,0671,048,892Form
4Peng, Katie DirectSell706202653.885,446293,4051,847,974Form
5Gilman, Michael DirectSell706202653.872,544137,0583,206,154Form
6Woods, KeithChief Operating OfficerDirectSell420202649.5710,220506,65130,738,917Form
7Vaishnaw, AkshayPresident of R&DDirectSell420202649.5712,246607,08931,258,804Form
8Sinha, VikasChief Financial OfficerDirectSell420202649.5710,410516,07130,729,051Form
9Hallal, DavidChief Executive OfficerDirectSell420202649.5730,6151,517,72381,254,291Form
10Qatanani, MoCHIEF SCIENTIFIC OFFICERDirectSell225202647.078,484399,3514,633,909Form
11Parlavecchio, CarynCHRODirectSell219202646.539,035420,3827,867,314Form
12Qatanani, MoCHIEF SCIENTIFIC OFFICERDirectSell219202646.537,989371,7144,975,214Form
13Marantz, Jing LCHIEF MEDICAL OFFICERDirectSell219202646.534,157193,4185,863,112Form
14Ho, JunlinGENERAL COUNSELDirectSell219202646.539,580445,74011,238,654Form
15Qatanani, MoCHIEF SCIENTIFIC OFFICERDirectSell123202646.7114,898695,9384,001,477Form
16Qatanani, MoCHIEF SCIENTIFIC OFFICERDirectSell121202644.488,406373,8804,472,589Form
17Parlavecchio, CarynCHRODirectSell121202644.486,600293,5536,621,128Form
18Marantz, Jing LCHIEF MEDICAL OFFICERDirectSell121202644.485,798257,8824,255,938Form
19Ho, JunlinGENERAL COUNSELDirectSell121202644.488,016356,5339,542,824Form
20Qatanani, MoCHIEF SCIENTIFIC OFFICERDirectSell116202645.2013,112592,6114,924,748Form
21Sinha, VikasChief Financial OfficerDirectSell115202642.7016,755715,43824,904,562Form
22Woods, KeithChief Operating OfficerDirectSell115202642.7016,746715,05424,904,946Form
23Vaishnaw, AkshayPresident of R&DDirectSell115202642.7020,438872,70325,439,251Form
24Hallal, DavidChief Executive OfficerDirectSell115202642.7057,4502,453,11565,828,242Form
25Peng, KatieDirectSell1218202544.091,00644,3521,450,820Form
26Akkaraju, SrinivasSamsara Opportunity Fund, L.P.Buy1216202539.9229,5991,181,63421,159,862Form
27Qatanani, MoCHIEF SCIENTIFIC OFFICERDirectSell1205202545.21136,4626,169,7884,926,535Form
28Akkaraju, SrinivasSamsara Opportunity Fund, L.P.Buy1007202538.65113,0254,368,80819,343,703Form
29Akkaraju, SrinivasSamsara Opportunity Fund, L.P.Buy1007202537.27387,41414,438,54414,438,544Form
30Qatanani, MoCHIEF SCIENTIFIC OFFICERDirectSell924202530.673,353102,8463,342,242Form
31Peng, KatieDirectSell917202532.531,00632,7261,103,240Form
32Qatanani, MoCHIEF SCIENTIFIC OFFICERDirectSell917202533.523,178106,5273,764,866Form
33Parlavecchio, CarynCHRODirectSell819202531.172,17867,8804,845,238Form
34Flier, Jeffrey STrustSell718202540.0211,136  Form
35Qatanani, MoCHIEF SCIENTIFIC OFFICERDirectSell710202534.4424,066828,8983,977,960Form
Core Cache Last Updated: 7/9/2026