Tearsheet

Pacira BioSciences (PCRX)


Market Price (4/25/2026): $24.505 | Market Cap: $1.0 Bil
Sector: Health Care | Industry: Pharmaceuticals

Pacira BioSciences (PCRX)


Market Price (4/25/2026): $24.505
Market Cap: $1.0 Bil
Sector: Health Care
Industry: Pharmaceuticals

Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.

0

Attractive cash flow generation
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 21%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 19%

Attractive yield
FCF Yield is 13%

Low stock price volatility
Vol 12M is 37%

Megatrend and thematic drivers
Megatrends include Precision Medicine, and Aging Population & Chronic Disease. Themes include Targeted Therapies, and Geriatric Care.

Weak multi-year price returns
2Y Excs Rtn is -51%, 3Y Excs Rtn is -118%

Meaningful short interest
Short Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 17%

Expensive valuation multiples
P/EBITPrice/EBIT or Price/(Operating Income) ratio is 33x, P/EPrice/Earnings or Price/(Net Income) is 148x

Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -3.3%

Significant short interest
Short Interest Days-to-CoverDTC = (Short Interest Share Quantity) / (Average Daily Trading Volume). Reflects how many days it would take to cover (close out) the short interest based on average volumes. High DTC can signify an increased risk of a short squeeze. is 15.7

Key risks
PCRX key risks include [1] an overwhelming revenue dependence on its flagship products, Show more.

0 Attractive cash flow generation
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 21%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 19%
1 Attractive yield
FCF Yield is 13%
2 Low stock price volatility
Vol 12M is 37%
3 Megatrend and thematic drivers
Megatrends include Precision Medicine, and Aging Population & Chronic Disease. Themes include Targeted Therapies, and Geriatric Care.
4 Weak multi-year price returns
2Y Excs Rtn is -51%, 3Y Excs Rtn is -118%
5 Meaningful short interest
Short Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 17%
6 Expensive valuation multiples
P/EBITPrice/EBIT or Price/(Operating Income) ratio is 33x, P/EPrice/Earnings or Price/(Net Income) is 148x
7 Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -3.3%
8 Significant short interest
Short Interest Days-to-CoverDTC = (Short Interest Share Quantity) / (Average Daily Trading Volume). Reflects how many days it would take to cover (close out) the short interest based on average volumes. High DTC can signify an increased risk of a short squeeze. is 15.7
9 Key risks
PCRX key risks include [1] an overwhelming revenue dependence on its flagship products, Show more.

Valuation, Metrics & Events

Price Chart

Why The Stock Moved

Qualitative Assessment

AI Analysis | Feedback

Pacira BioSciences (PCRX) stock has lost about 5% since 12/31/2025 because of the following key factors:

1. Pacira BioSciences' stock experienced a decline of approximately 9.01% in market capitalization from December 31, 2025 ($1.11 billion), to April 15, 2026 ($1.01 billion). This significant drop in valuation contributed to the negative trend observed for the specified period.

2. The company's fourth-quarter 2025 financial results, reported on February 26, 2026, missed analysts' expectations. Pacira BioSciences reported earnings per share (EPS) of $0.57, falling short of the consensus estimate of $0.85 by $0.28. Additionally, quarterly revenue of $196.87 million was below analysts' expectations of $201.93 million. This earnings and revenue miss led to a 3.71% stock decline on February 27, 2026.

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Stock Movement Drivers

Fundamental Drivers

The -5.3% change in PCRX stock from 12/31/2025 to 4/24/2026 was primarily driven by a -67.6% change in the company's Net Income Margin (%).
(LTM values as of)123120254242026Change
Stock Price ($)25.8824.51-5.3%
Change Contribution By: 
Total Revenues ($ Mil)7177261.3%
Net Income Margin (%)3.0%1.0%-67.6%
P/E Multiple53.2148.1178.5%
Shares Outstanding (Mil)44423.6%
Cumulative Contribution-5.3%

LTM = Last Twelve Months as of date shown

Market Drivers

12/31/2025 to 4/24/2026
ReturnCorrelation
PCRX-5.3% 
Market (SPY)4.2%13.0%
Sector (XLV)-6.9%26.1%

Fundamental Drivers

The -4.9% change in PCRX stock from 9/30/2025 to 4/24/2026 was primarily driven by a -13.6% change in the company's P/S Multiple.
(LTM values as of)93020254242026Change
Stock Price ($)25.7724.51-4.9%
Change Contribution By: 
Total Revenues ($ Mil)7067262.9%
P/S Multiple1.71.4-13.6%
Shares Outstanding (Mil)45427.0%
Cumulative Contribution-4.9%

LTM = Last Twelve Months as of date shown

Market Drivers

9/30/2025 to 4/24/2026
ReturnCorrelation
PCRX-4.9% 
Market (SPY)7.0%17.7%
Sector (XLV)4.0%25.4%

Fundamental Drivers

The -1.4% change in PCRX stock from 3/31/2025 to 4/24/2026 was primarily driven by a -12.4% change in the company's P/S Multiple.
(LTM values as of)33120254242026Change
Stock Price ($)24.8524.51-1.4%
Change Contribution By: 
Total Revenues ($ Mil)7017263.6%
P/S Multiple1.61.4-12.4%
Shares Outstanding (Mil)46428.7%
Cumulative Contribution-1.4%

LTM = Last Twelve Months as of date shown

Market Drivers

3/31/2025 to 4/24/2026
ReturnCorrelation
PCRX-1.4% 
Market (SPY)28.1%13.4%
Sector (XLV)0.1%24.8%

Fundamental Drivers

The -39.9% change in PCRX stock from 3/31/2023 to 4/24/2026 was primarily driven by a -59.4% change in the company's Net Income Margin (%).
(LTM values as of)33120234242026Change
Stock Price ($)40.8124.51-39.9%
Change Contribution By: 
Total Revenues ($ Mil)6677268.9%
Net Income Margin (%)2.4%1.0%-59.4%
P/E Multiple117.7148.125.8%
Shares Outstanding (Mil)46428.0%
Cumulative Contribution-39.9%

LTM = Last Twelve Months as of date shown

Market Drivers

3/31/2023 to 4/24/2026
ReturnCorrelation
PCRX-39.9% 
Market (SPY)79.8%10.7%
Sector (XLV)16.6%15.2%

Return vs. Risk

Price Returns Compared

 202120222023202420252026Total [1]
Returns
PCRX Return1%-36%-13%-44%37%-2%-58%
Peers Return-9%12%-10%-13%-0%32%5%
S&P 500 Return27%-19%24%23%16%4%89%

Monthly Win Rates [3]
PCRX Win Rate50%33%42%33%50%75% 
Peers Win Rate38%48%47%47%52%45% 
S&P 500 Win Rate75%42%67%75%67%50% 

Max Drawdowns [4]
PCRX Max Drawdown-20%-37%-32%-65%-3%-26% 
Peers Max Drawdown-35%-31%-40%-22%-26%-16% 
S&P 500 Max Drawdown-1%-25%-1%-2%-15%-7% 


[1] Cumulative total returns since the beginning of 2021
[2] Peers: HRTX, AVNS, COLL, ASRT, VRTX.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 4/24/2026 (YTD)

How Low Can It Go

Unique KeyEventPCRXS&P 500
2022 Inflation Shock2022 Inflation Shock  
2022 Inflation Shock% Loss% Loss-67.8%-25.4%
2022 Inflation Shock% Gain to Breakeven% Gain to Breakeven210.2%34.1%
2022 Inflation ShockTime to BreakevenTime to BreakevenNot Fully Recovered days464 days
2020 Covid Pandemic2020 Covid Pandemic  
2020 Covid Pandemic% Loss% Loss-44.0%-33.9%
2020 Covid Pandemic% Gain to Breakeven% Gain to Breakeven78.5%51.3%
2020 Covid PandemicTime to BreakevenTime to Breakeven98 days148 days
2018 Correction2018 Correction  
2018 Correction% Loss% Loss-46.8%-19.8%
2018 Correction% Gain to Breakeven% Gain to Breakeven88.0%24.7%
2018 CorrectionTime to BreakevenTime to Breakeven171 days120 days

Compare to HRTX, AVNS, COLL, ASRT, VRTX

In The Past

Pacira BioSciences's stock fell -67.8% during the 2022 Inflation Shock from a high on 4/8/2022. A -67.8% loss requires a 210.2% gain to breakeven.

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About Pacira BioSciences (PCRX)

Pacira BioSciences, Inc. provides non-opioid pain management and regenerative health solutions for healthcare practitioners and their patients in the United States. The company offers EXPAREL, a bupivacaine liposome injectable suspension; ZILRETTA, a triamcinolone acetonide extended-release injectable suspension; and iovera system, a non-opioid handheld cryoanalgesia device used to produce controlled doses of cold temperature only to targeted nerves. It also develops proprietary multivesicular liposome, a drug delivery technology that encapsulates drugs without altering their molecular structure. The company was formerly known as Pacira Pharmaceuticals, Inc. and changed its name to Pacira BioSciences, Inc. in April 2019. Pacira BioSciences, Inc. was incorporated in 2006 and is headquartered in Tampa, Florida.

AI Analysis | Feedback

Here are 1-3 brief analogies for Pacira BioSciences (PCRX):

  • Like Amgen or Gilead Sciences for non-opioid pain solutions.
  • Like Medtronic for non-opioid pain management technology.
  • Like Moderna for non-opioid pain therapies.

AI Analysis | Feedback

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  • EXPAREL: A bupivacaine liposome injectable suspension for non-opioid pain management.
  • ZILRETTA: A triamcinolone acetonide extended-release injectable suspension for pain management.
  • iovera system: A non-opioid handheld cryoanalgesia device that produces controlled doses of cold temperature to targeted nerves.
  • Proprietary multivesicular liposome: A drug delivery technology that encapsulates drugs without altering their molecular structure.
```

AI Analysis | Feedback

Pacira BioSciences (PCRX) primarily sells its products through major pharmaceutical wholesalers. These wholesalers then distribute Pacira's non-opioid pain management and regenerative health solutions to hospitals, ambulatory surgical centers, and physician practices across the United States.

Based on the company's public filings, its major customers, representing a significant portion of its product net revenue, are:

  • AmerisourceBergen Corporation (Symbol: ABC)
  • Cardinal Health, Inc. (Symbol: CAH)
  • McKesson Corporation (Symbol: MCK)

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Frank D. Lee Chief Executive Officer & Director Mr. Lee joined Pacira BioSciences as Chief Executive Officer and a member of the Board of Directors in January 2024. He is an accomplished biopharmaceutical leader with thirty years of global experience. Prior to Pacira, he served as Chief Executive Officer and a director of the publicly traded Forma Therapeutics from March 2019 until its acquisition by Novo Nordisk in October 2022. During his tenure, he transformed Forma Therapeutics from an early-stage drug discovery company into one focused on clinical development. Before Forma, he spent 13 years at Genentech, a member of the Roche Group, in various leadership roles, including Senior Vice President, Global Product Strategy and Therapeutic Area Head for Immunology, Ophthalmology and Infectious Diseases, overseeing global product sales of $11 billion. Earlier in his career, he spent approximately 13 years across Novartis, Janssen, and Eli Lilly in engineering, manufacturing, sales/marketing, and business development. Mr. Lee currently serves as a Director of Bausch Health Companies, Inc. and as an Advisor to Lightstone Ventures. He also served as executive chairman of the board of privately held Therini Bio, Inc. and chairman of the board of privately held Catamaran Bio, Inc., and a member of the board of Bolt Biotherapeutics, Inc. Shawn Cross Chief Financial Officer Mr. Cross was appointed Chief Financial Officer of Pacira BioSciences in October 2024. He brings over 25 years of experience in the biopharmaceutical sector, including as a biotechnology executive, board member, and investment banker. Before joining Pacira, he was a member of the leadership team at Applied Molecular Transport Inc. (AMT), where he served as Chief Financial Officer from March 2020 to May 2022, President and Chief Operating Officer from May 2022 to March 2023, and Chief Executive Officer and a director from March 2023 through the closing of its merger with Cyclo Therapeutics, Inc. in December 2023. He led AMT through its initial public offering. Prior to AMT, Mr. Cross was an investment banker for more than 20 years, focusing on the biopharmaceutical industry, with senior roles at JMP Securities, Deutsche Bank Securities, Wells Fargo Securities, and Thomas Weisel Partners. He began his investment banking career at Alex. Brown & Sons. Mr. Cross currently serves on the board of directors of Cyclo Therapeutics. Brendan Teehan Chief Commercial Officer Mr. Teehan was named Chief Commercial Officer of Pacira BioSciences in January 2025. He is an accomplished biopharmaceutical executive with a 30-year track record of successfully building and leading commercial teams. Prior to joining Pacira, he held various commercial leadership positions at Acadia Pharmaceuticals, Inc., most recently as Chief Operating Officer and Head of Commercial. He also served in commercial leadership roles at Tesaro, Inc., Raintree Oncology Services, Amgen, Inc., and Johnson & Johnson. Mr. Teehan has extensive expertise in both privately and publicly held companies across multiple large and rare disease therapeutic categories and development stages. Krys Corbett Chief Business Officer Ms. Corbett was named Chief Business Officer of Pacira BioSciences in January 2025. She brings more than 25 years of industry experience across business development, strategic transactions, alliance management, and product portfolio management. Before joining Pacira, she led portfolio and product strategy for clinical and preclinical-stage programs at Lyell Immunopharma. She also served as Head of Business Development, General Counsel, and Corporate Secretary for Oric Pharmaceuticals. Earlier in her career, Ms. Corbett held alliance and asset management leadership roles at Roche and Genentech. She began her career at the law firm Wilson Sonsini Goodrich and Rosati. Kristen Williams, Esq. Chief Administrative Officer & Secretary Ms. Williams serves as Chief Administrative Officer & Secretary at Pacira BioSciences. She holds a Bachelor of Science Degree in Business Administration from Bucknell University and a J.D. Degree from the University of Denver, College of Law.

AI Analysis | Feedback

Pacira BioSciences (PCRX) faces several key risks to its business, primarily stemming from its reliance on core products, the ongoing threat of generic competition, and intense market dynamics.

  1. High Dependence on Key Products: Pacira BioSciences exhibits a significant dependence on a limited number of products, with EXPAREL and ZILRETTA accounting for 95% of its total revenue in 2024. EXPAREL alone contributed 78% of the company's total revenue in the same year. This concentration makes the company particularly vulnerable to market shifts, regulatory challenges, or competitive pressures impacting these products.

  2. Generic Competition and Patent Erosion for EXPAREL: Despite comprehensive patent strategies and recent litigation settlements, the threat of generic competition for its flagship product, EXPAREL, remains a key risk. While some EXPAREL patents extend into the 2040s, a settlement in April 2025 permits volume-limited generic bupivacaine liposome injectable suspension to enter the U.S. market starting in early 2030, with unlimited generic production allowed from 2039. Additionally, a 2024 district court ruling invalidated one of Pacira's patents, potentially opening the door for generic entry, though the manufacturing complexity of EXPAREL’s proprietary multivesicular liposome (pMVL) technology is noted as a significant barrier.

  3. Intense Competition and Market Adoption Challenges: The pain management market is highly competitive and dynamic, posing a continuous challenge for Pacira BioSciences. The company faces direct competition from other long-acting anesthetics, such as Heron Therapeutics’ ZYNRELEF, and larger pharmaceutical companies investing in non-opioid pain relief solutions. Moreover, products like ZILRETTA have experienced challenges with market traction and sales force transitions, and the iovera system competes in a field with numerous emerging players. Changes in healthcare policies, insurance coverage, and reimbursement rates also present regulatory and market risks that can impact the profitability and adoption of Pacira's products.

AI Analysis | Feedback

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AI Analysis | Feedback

Pacira BioSciences, Inc. (symbol: PCRX) operates in the non-opioid pain management and regenerative health solutions markets with its key products EXPAREL, ZILRETTA, and the iovera system.

Here are the addressable market sizes for their main products:

  • EXPAREL (bupivacaine liposome injectable suspension): The global EXPAREL market size was valued at approximately $1.2 billion in 2023 and is forecasted to reach $3.1 billion by 2032. North America accounted for approximately 45% of the global market in 2023.
  • ZILRETTA (triamcinolone acetonide extended-release injectable suspension): The broader global intra-articular corticosteroid market, which includes ZILRETTA, was valued at approximately $1.6 billion globally in 2022. More specifically for its indication, the U.S. knee osteoarthritis (OA) injectable treatments market size was $1.02 billion in 2024 and is projected to reach around $1.95 billion by 2034.
  • iovera system (cryoanalgesia device): Null

AI Analysis | Feedback

Pacira BioSciences (PCRX) is expected to drive future revenue growth over the next 2-3 years through several key initiatives and product expansions:

  1. Accelerated EXPAREL Volume Growth and Expanded Market Access: Pacira anticipates continued growth from its flagship product, EXPAREL, driven by increased volume, broader commercial and government reimbursement access, and expanded patent protection extending through 2039. The NOPAIN Act is also cited as positively impacting the adoption and reimbursement of non-opioid alternatives, thereby enhancing EXPAREL's market presence.
  2. Strategic Partnerships for ZILRETTA and International Expansion: The company's strategic collaboration with Johnson & Johnson MedTech is projected to significantly expand the market reach of ZILRETTA by tripling promotional efforts and extending its presence into new physician specialties. Additionally, a partnership with LG Chem is aimed at expanding EXPAREL and ZILRETTA coverage in select Asia-Pacific markets, with initial revenues expected in 2027.
  3. Growing Adoption and Expanded Indications for iovera System: The iovera system is demonstrating promising outcomes in studies for chronic low back pain, showing better results than traditional radiofrequency ablation. Recent FDA clearance for a new SmartTip designed for deeper nerve access in lumbar applications further supports the potential for increased utilization and growth, particularly in spine-related pain management.
  4. Advancement of Pipeline Products: Pacira is investing in and progressing its pipeline, including PCRX-201, a gene therapy for osteoarthritis, and PCRX-2002, a ropivacaine-based long-acting local analgesic. Key data readouts for these programs are anticipated, offering potential for future revenue streams beyond the current commercial portfolio.
  5. Execution of the "5x30" Strategy: Pacira's overarching "5x30" strategy aims to significantly increase patient access to its products, targeting 3 million patients annually by 2030. This strategy emphasizes accelerating commercial portfolio growth, enhancing market penetration, and fostering continuous innovation across its product lines, thereby serving as a broad driver for revenue growth.

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Share Repurchases

  • Pacira BioSciences authorized a new share repurchase program of up to $300 million on April 17, 2025, which supersedes a previous authorization from May 7, 2024, and is set to expire on December 31, 2026.
  • In 2025, the company completed $150 million in stock repurchases, reducing the shares outstanding to 41 million.
  • From October 1, 2025, to December 31, 2025, Pacira repurchased 2,000,000 shares for $50 million, completing the repurchase of 5,932,106 shares for $150.05 million under the buyback announced on May 8, 2025.

Outbound Investments

  • In February 2025, Pacira acquired the remaining 81% equity interest of GQ Bio Therapeutics GmbH for approximately $32 million, building on prior investments and partnerships for the development of a gene therapy platform.
  • In November 2021, Pacira acquired Flexion Therapeutics for approximately $425 million, which strengthened its position in non-opioid pain management.
  • Pacira BioSciences entered into an exclusive global licensing agreement with AmacaThera for US$230 million in November 2025.

Capital Expenditures

  • Capital expenditures for Pacira BioSciences were $40 million in 2025, $25 million in 2024, $19 million in 2023, $15 million in 2022, and $10 million in 2021.
  • The company has invested in its 200-liter facilities in Swindon and San Diego to enhance manufacturing efficiencies and ensure ample production capacity.

Better Bets vs. Pacira BioSciences (PCRX)

Trade Ideas

Select ideas related to PCRX.

Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
PGNY_3312026_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG03312026PGNYProgynyDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
0.0%0.0%0.0%
CNC_3272026_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG03272026CNCCenteneDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
2.3%2.3%-0.6%
OSCR_3272026_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG03272026OSCROscar HealthDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
3.0%3.0%-2.6%
WAT_3202026_Monopoly_xInd_xCD_Getting_Cheaper03202026WATWatersMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
-0.4%-0.4%-3.3%
GILD_3202026_Quality_Momentum_RoomToRun_10%03202026GILDGilead SciencesQualityQ | Momentum | UpsideQuality Stocks with Momentum and Upside
Buying quality stocks with strong momentum but still having room to run
1.6%1.6%-2.2%
PCRX_12312022_Dip_Buyer_High_CFO_Margins_ExInd_DE12312022PCRXPacira BioSciencesDip BuyDB | CFO/Rev | Low D/EDip Buy with High Cash Flow Margins
Buying dips for companies with significant cash flows from operations and reasonable debt / market cap
3.8%-12.6%-31.8%

Recent Active Movers

Peer Comparisons

Peers to compare with:

Financials

PCRXHRTXAVNSCOLLASRTVRTXMedian
NamePacira B.Heron Th.Avanos M.Collegiu.Assertio Vertex P. 
Mkt Price24.511.1924.6632.5018.04430.2924.59
Mkt Cap1.00.21.11.00.1109.11.0
Rev LTM72615570178111912,001714
Op Inc LTM34-315178-174,55425
FCF LTM137-2843328-283,19490
FCF 3Y Avg152-3747268161,83299
CFO LTM152-2875329-283,631113
CFO 3Y Avg165-3669270162,225117

Growth & Margins

PCRXHRTXAVNSCOLLASRTVRTXMedian
NamePacira B.Heron Th.Avanos M.Collegiu.Assertio Vertex P. 
Rev Chg LTM3.6%7.4%1.9%23.6%-5.0%8.9%5.5%
Rev Chg 3Y Avg2.9%13.0%-0.9%19.1%-8.5%10.4%6.6%
Rev Chg Q5.1%-0.5%0.7%12.9%-57.9%9.5%2.9%
QoQ Delta Rev Chg LTM1.3%-0.1%0.2%3.1%-13.6%2.4%0.8%
Op Inc Chg LTM-65.5%78.0%-62.0%6.9%8.3%2,051.3%7.6%
Op Inc Chg 3Y Avg-10.2%68.1%237.0%136.0%-93.7%644.7%102.0%
Op Mgn LTM4.6%-1.6%2.2%22.9%-14.5%37.9%3.4%
Op Mgn 3Y Avg10.5%-32.2%2.9%26.3%-6.3%24.7%6.7%
QoQ Delta Op Mgn LTM-3.7%-2.7%-2.2%2.7%-2.2%38.7%-2.2%
CFO/Rev LTM20.9%-17.8%10.7%42.2%-23.7%30.3%15.8%
CFO/Rev 3Y Avg23.6%-26.6%10.0%41.0%10.0%20.5%15.3%
FCF/Rev LTM18.8%-18.0%6.1%42.0%-23.7%26.6%12.5%
FCF/Rev 3Y Avg21.7%-27.3%6.8%40.9%10.0%17.0%13.5%

Valuation

PCRXHRTXAVNSCOLLASRTVRTXMedian
NamePacira B.Heron Th.Avanos M.Collegiu.Assertio Vertex P. 
Mkt Cap1.00.21.11.00.1109.11.0
P/S1.41.41.61.31.09.11.4
P/Op Inc30.9-88.374.15.8-6.724.014.9
P/EBIT33.1-21.2-19.65.9-4.223.40.8
P/E148.1-11.1-15.716.4-3.827.66.3
P/CFO6.9-8.115.33.1-4.130.05.0
Total Yield0.7%-9.0%-6.4%6.1%-26.2%3.6%-2.9%
Dividend Yield0.0%0.0%0.0%0.0%0.0%0.0%0.0%
FCF Yield 3Y Avg14.0%-15.0%7.0%24.0%10.7%1.7%8.9%
D/E0.40.60.10.80.30.00.4
Net D/E0.20.40.00.4-0.2-0.00.1

Returns

PCRXHRTXAVNSCOLLASRTVRTXMedian
NamePacira B.Heron Th.Avanos M.Collegiu.Assertio Vertex P. 
1M Rtn4.3%49.4%78.7%-2.3%-2.9%-5.4%1.0%
3M Rtn18.6%-16.2%88.4%-28.6%56.7%-8.1%5.2%
6M Rtn12.7%-0.8%109.2%-7.9%46.6%2.1%7.4%
12M Rtn-5.7%-47.6%96.8%21.4%90.9%-12.6%7.8%
3Y Rtn-44.8%-52.8%-18.5%42.7%-77.6%29.6%-31.6%
1M Excs Rtn-4.4%40.7%70.0%-11.0%-11.5%-14.1%-7.7%
3M Excs Rtn15.0%-19.8%84.8%-32.2%53.1%-11.7%1.6%
6M Excs Rtn7.1%-7.0%101.5%-15.9%41.5%-6.0%0.5%
12M Excs Rtn-36.0%-79.2%65.1%-8.2%65.7%-45.9%-22.1%
3Y Excs Rtn-118.5%-128.4%-91.1%-30.4%-152.6%-41.5%-104.8%

Comparison Analyses

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Financials

Segment Financials

Revenue by Segment
$ Mil20252024202320222021
EXPAREL549538537507413
ZILRETTA11811110613 
iovera°232015169
Bupivacaine liposome injectable suspension73644
Royalty revenue43323
Collaborative licensing and milestone revenue  00 
Total701675667542430


Price Behavior

Price Behavior
Market Price$24.51 
Market Cap ($ Bil)1.0 
First Trading Date02/03/2011 
Distance from 52W High-10.0% 
   50 Days200 Days
DMA Price$23.07$23.58
DMA Trendindeterminateup
Distance from DMA6.3%4.0%
 3M1YR
Volatility34.0%37.4%
Downside Capture0.030.41
Upside Capture74.2844.11
Correlation (SPY)21.9%16.4%
PCRX Betas & Captures as of 3/31/2026

 1M2M3M6M1Y3Y
Beta0.270.830.460.600.290.36
Up Beta3.931.173.041.48-0.030.14
Down Beta1.461.290.330.710.540.47
Up Capture-14%145%-27%21%27%7%
Bmk +ve Days7162765139424
Stock +ve Days12253572126379
Down Capture-70%-0%32%49%63%79%
Bmk -ve Days12233358110323
Stock -ve Days9162753124368

[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with PCRX
PCRX-2.8%37.5%0.00-
Sector ETF (XLV)7.7%15.8%0.2826.7%
Equity (SPY)34.0%12.6%2.0516.5%
Gold (GLD)42.9%27.2%1.292.6%
Commodities (DBC)46.4%18.0%1.97-10.2%
Real Estate (VNQ)14.2%13.3%0.7417.5%
Bitcoin (BTCUSD)-16.6%42.1%-0.3210.5%

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Based On 5-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with PCRX
PCRX-17.4%45.5%-0.24-
Sector ETF (XLV)5.1%14.6%0.1723.5%
Equity (SPY)12.7%17.1%0.5822.1%
Gold (GLD)21.2%17.8%0.975.2%
Commodities (DBC)14.5%19.1%0.623.9%
Real Estate (VNQ)3.7%18.8%0.1020.4%
Bitcoin (BTCUSD)7.0%56.3%0.349.3%

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Based On 10-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with PCRX
PCRX-9.2%47.1%-0.02-
Sector ETF (XLV)9.3%16.5%0.4631.9%
Equity (SPY)14.9%17.9%0.7130.6%
Gold (GLD)13.9%15.9%0.730.1%
Commodities (DBC)10.1%17.8%0.479.7%
Real Estate (VNQ)5.4%20.7%0.2325.5%
Bitcoin (BTCUSD)68.3%66.9%1.077.8%

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Short Interest

Short Interest: As Of Date4152026
Short Interest: Shares Quantity7.4 Mil
Short Interest: % Change Since 3312026-8.3%
Average Daily Volume0.5 Mil
Days-to-Cover Short Interest15.7 days
Basic Shares Quantity42.5 Mil
Short % of Basic Shares17.4%

Earnings Returns History

Expand for More
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
2/26/2026-3.0%1.2%1.3%
11/6/20254.5%11.9%17.4%
8/5/2025-0.6%10.1%18.6%
5/8/20250.8%2.8%2.0%
2/27/2025-5.2%-6.0%-1.9%
11/6/20240.2%-6.9%9.1%
7/30/20245.7%10.6%-23.7%
2/29/2024-0.6%0.7%-2.3%
...
SUMMARY STATS   
# Positive141513
# Negative9810
Median Positive2.1%4.6%9.8%
Median Negative-3.0%-3.7%-4.3%
Max Positive7.5%16.7%22.5%
Max Negative-7.2%-8.2%-23.7%

SEC Filings

Expand for More
Report DateFiling DateFiling
12/31/202502/26/202610-K
09/30/202511/06/202510-Q
06/30/202508/05/202510-Q
03/31/202505/08/202510-Q
12/31/202402/27/202510-K
09/30/202411/06/202410-Q
06/30/202407/30/202410-Q
03/31/202405/07/202410-Q
12/31/202302/29/202410-K
09/30/202311/02/202310-Q
06/30/202308/02/202310-Q
03/31/202305/03/202310-Q
12/31/202202/28/202310-K
09/30/202211/03/202210-Q
06/30/202208/03/202210-Q
03/31/202205/04/202210-Q

Recent Forward Guidance [BETA]

Latest: Q4 2025 Earnings Reported 2/26/2026

Forward GuidanceGuidance Change
MetricLowMidHigh% Chg% DeltaChangePrior
2026 EXPAREL net product sales600.00 Mil610.00 Mil620.00 Mil   
2026 Total revenue745.00 Mil757.50 Mil770.00 Mil   
2026 Non-GAAP gross margin77.0%78.0%79.0%   
2026 Non-GAAP R&D expense105.00 Mil110.00 Mil115.00 Mil   
2026 Non-GAAP SG&A expense320.00 Mil330.00 Mil340.00 Mil   
2026 Stock-based compensation54.00 Mil58.00 Mil62.00 Mil   
2026 Share Repurchases 150.00 Mil    

Prior: Q4 2025 Earnings Reported 1/8/2026

Forward GuidanceGuidance Change
MetricLowMidHigh% Chg% DeltaChangePrior
2026 Share Repurchases 150.00 Mil