Tearsheet

Kairos Pharma (KAPA)


Market Price (12/24/2025): $0.752 | Market Cap: $15.2 Mil
Sector: Health Care | Industry: Biotechnology

Kairos Pharma (KAPA)


Market Price (12/24/2025): $0.752
Market Cap: $15.2 Mil
Sector: Health Care
Industry: Biotechnology

Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.


0 Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -37%
Penny stock
Mkt Price is 0.8
1 Megatrend and thematic drivers
Megatrends include Biotechnology & Genomics, and Precision Medicine. Themes include Gene Editing & Therapy, Targeted Therapies, Show more.
Very low revenue
Rev LTMTotal Revenue or Sales, Last Twelve Months is 0
2  Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -5.6 Mil
3  Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -38%
4  High stock price volatility
Vol 12M is 178%
5  Key risks
KAPA key risks include [1] its heavy dependence on the successful outcome of clinical trials for its lead candidate, Show more.
0 Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -37%
1 Megatrend and thematic drivers
Megatrends include Biotechnology & Genomics, and Precision Medicine. Themes include Gene Editing & Therapy, Targeted Therapies, Show more.
2 Penny stock
Mkt Price is 0.8
3 Very low revenue
Rev LTMTotal Revenue or Sales, Last Twelve Months is 0
4 Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -5.6 Mil
5 Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -38%
6 High stock price volatility
Vol 12M is 178%
7 Key risks
KAPA key risks include [1] its heavy dependence on the successful outcome of clinical trials for its lead candidate, Show more.

Valuation, Metrics & Events

KAPA Stock


Why The Stock Moved


Qualitative Assessment

AI Analysis | Feedback

Here are key points highlighting why Kairos Pharma (KAPA) stock moved by -44.3% from approximately August 31, 2025, to December 24, 2025: 1. Continued Financial Losses and No Revenue. Kairos Pharma reported a net loss of $1.4 million for the third quarter ended September 30, 2025, with no revenue. The company's operating expenses increased as development advanced, raising concerns about ongoing profitability and cash burn.

2. Bearish Market Sentiment and Technical Signals. Despite some positive analyst ratings, several market analyses and technical indicators, particularly from algorithmic platforms, signaled a bearish outlook for KAPA. As of December 17, 2025, Wallet Investor indicated a "Strong Sell" and predicted a further drop in the stock price, while Intellectia AI also issued a "Strong Sell" recommendation based on negative technical signals and a falling trend.

Show more

Stock Movement Drivers

Fundamental Drivers

The -34.6% change in KAPA stock from 9/23/2025 to 12/23/2025 was primarily driven by a -17.4% change in the company's Shares Outstanding (Mil).
923202512232025Change
Stock Price ($)1.150.75-34.61%
Change Contribution ByLTMLTM
Total Revenues ($ Mil)0.000.00
P/S Multiple
Shares Outstanding (Mil)17.2120.21-17.39%
Cumulative Contribution

LTM = Last Twelve Months as of date shown

Market Drivers

9/23/2025 to 12/23/2025
ReturnCorrelation
KAPA-34.6% 
Market (SPY)3.7%53.2%
Sector (XLV)13.2%6.6%

Fundamental Drivers

The 15.9% change in KAPA stock from 6/24/2025 to 12/23/2025 was primarily driven by a 0.0% change in the company's Total Revenues ($ Mil).
624202512232025Change
Stock Price ($)0.650.7515.87%
Change Contribution ByLTMLTM
Total Revenues ($ Mil)0.000.00
P/S Multiple
Shares Outstanding (Mil)15.8820.21-27.28%
Cumulative Contribution

LTM = Last Twelve Months as of date shown

Market Drivers

6/24/2025 to 12/23/2025
ReturnCorrelation
KAPA15.9% 
Market (SPY)13.7%14.5%
Sector (XLV)16.4%-7.3%

Fundamental Drivers

The -56.2% change in KAPA stock from 12/23/2024 to 12/23/2025 was primarily driven by a -85.2% change in the company's Shares Outstanding (Mil).
1223202412232025Change
Stock Price ($)1.720.75-56.15%
Change Contribution ByLTMLTM
Total Revenues ($ Mil)0.000.00
P/S Multiple
Shares Outstanding (Mil)10.9120.21-85.20%
Cumulative Contribution

LTM = Last Twelve Months as of date shown

Market Drivers

12/23/2024 to 12/23/2025
ReturnCorrelation
KAPA-56.2% 
Market (SPY)16.7%5.2%
Sector (XLV)13.2%2.7%

Fundamental Drivers

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Market Drivers

12/24/2023 to 12/23/2025
ReturnCorrelation
KAPA  
Market (SPY)48.4%5.8%
Sector (XLV)18.2%2.9%

Return vs. Risk


Price Returns Compared

 202020212022202320242025Total [1]
Returns
KAPA Return-47%
Peers Return40%16%-1%10%1%27%128%
S&P 500 Return16%27%-19%24%23%17%114%

Monthly Win Rates [3]
KAPA Win Rate33%25% 
Peers Win Rate50%52%55%48%55%57% 
S&P 500 Win Rate58%75%42%67%75%73% 

Max Drawdowns [4]
KAPA Max Drawdown-70% 
Peers Max Drawdown-19%-13%-18%-18%-18%-22% 
S&P 500 Max Drawdown-31%-1%-25%-1%-2%-15% 


[1] Cumulative total returns since the beginning of 2020
[2] Peers: EXEL, RCUS, REGN, AMGN, BMY.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2025 data is for the year up to 12/23/2025 (YTD)

How Low Can It Go

KAPA has limited trading history. Below is the Health Care sector ETF (XLV) in its place.

Unique KeyEventXLVS&P 500
2022 Inflation Shock2022 Inflation Shock  
2022 Inflation Shock% Loss% Loss-16.1%-25.4%
2022 Inflation Shock% Gain to Breakeven% Gain to Breakeven19.1%34.1%
2022 Inflation ShockTime to BreakevenTime to Breakeven599 days464 days
2020 Covid Pandemic2020 Covid Pandemic  
2020 Covid Pandemic% Loss% Loss-28.8%-33.9%
2020 Covid Pandemic% Gain to Breakeven% Gain to Breakeven40.4%51.3%
2020 Covid PandemicTime to BreakevenTime to Breakeven116 days148 days
2018 Correction2018 Correction  
2018 Correction% Loss% Loss-15.8%-19.8%
2018 Correction% Gain to Breakeven% Gain to Breakeven18.8%24.7%
2018 CorrectionTime to BreakevenTime to Breakeven326 days120 days
2008 Global Financial Crisis2008 Global Financial Crisis  
2008 Global Financial Crisis% Loss% Loss-40.6%-56.8%
2008 Global Financial Crisis% Gain to Breakeven% Gain to Breakeven68.3%131.3%
2008 Global Financial CrisisTime to BreakevenTime to Breakeven1,100 days1,480 days

Compare to

In The Past

SPDR Select Sector Fund's stock fell -16.1% during the 2022 Inflation Shock from a high on 4/8/2022. A -16.1% loss requires a 19.1% gain to breakeven.

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About Kairos Pharma (KAPA)

We are a clinical-stage biopharmaceutical company advancing therapeutics for cancer patients that are designed to overcome key hurdles in immune suppression and drug resistance. These therapeutics include antibodies and small molecules for the treatment of prostate cancer, lung cancer, breast cancer and glioblastoma. We are driven by innovative science to develop novel and transformative drug therapies to treat cancer. Our mission is to advance our portfolio of innovative therapeutics to transform the way cancer is treated. We have leveraged molecular insights to develop a new class of novel drugs that we expect will target drug resistance and checkpoints of immune suppression. “Checkpoints” refer to molecules on certain immune cells that need to be activated (or inactivated) to start an immune response. Our portfolio of seven drug candidates offers diversification and mitigates the overall exposure to many of the inherent risks of drug development. Our key patents are licensed from Cedars-Sinai Medical Center, the largest academic medical center in the Western United States, and Tracon Pharmaceuticals, Inc., a clinical stage public biopharmaceutical company based in California. The science underlying the patents was developed at Cedars-Sinai Medical Center and was licensed to us from this institution. The human immune system can tell the difference between normal cells in the body and those it sees as “foreign,” which allows it to focus an attack on the foreign cells while leaving the normal cells alone. To do this, our immune system uses checkpoints. Cancer cells can find ways to use these checkpoints to avoid being attacked by the immune system. We are developing small molecules that we believe can specifically target these central checkpoints. In addition, we are developing an activated T cell therapy that is designed to transform a patient’s T cells into killer activated T cells against cancerous stem cells. These activated T cells are induced to target several antigen targets on glioblastoma cancer stem cells, the initiators and propagators of glioblastoma tumors. In June 2021, Kairos acquired Enviro Therapeutics, Inc., a California corporation (“Enviro”), through a share exchange. Enviro’s shareholders exchanged 100% of the outstanding shares of Enviro for 6,000,000 shares of newly issued restricted shares of common stock of Kairos. After the closing, Enviro became a wholly owned subsidiary of Kairos. The acquisition allowed us to incorporate into our company Enviro’s advanced pipeline of drug candidates in Phase 1 and Phase 2 trials. The pipeline includes two therapeutic agents addressing what we believe to be significant unmet needs in the prostate and lung cancer markets and that we believe can help address cancer progression in those cancers that develop resistance to standard therapies. Our drug candidate portfolio currently consists of a pipeline of seven drug candidates, including KROS drugs, which are immunotherapeutics, and ENV antibodies, which are designed to reverse drug resistance that often results as a consequence of the use of cancer therapeutics. Our pipeline is summarized below: . Five pre-clinical or clinical-trial stage drug candidates developed by us and designed to target immune response, including KROS 101, 102, 201, 301, and 401, which are designed to reverse immunosuppression of T cells that is caused by cancer. - KROS 101 and 102 are small molecules that are agonist and antagonist for the GITR (glucocorticoid induced TNF-like receptor) ligand, which respectively promote and inhibit T cell growth and function. GITR is a checkpoint central to control the numbers of T cells of the immune system. These molecules are in the preclinical stage and are being developed for clinical trials. - KROS 201 is an autologous T cell therapy targeting cancer stem cells of glioblastoma. This therapy has received an IND from the FDA for clinical trial and is undergoing preparation for a Phase 1 clinical trial for patients with recurrent glioblastoma. - KROS 301 is a small molecule that targets the NF-ĸß pathway, a cancer growth and immune suppressive molecule in triple negative breast cancer. This molecule is in preclinical testing. - KROS 401 is a cyclic peptide which inhibits the IL-4 and IL-13 (cytokines that play a critical role in the suppression of T cells by macrophages at the site of the tumor) receptor and is designed to reverse the immunosuppression induced by macrophages in the tumor microenvironment. . Two therapeutic agents developed by our Enviro subsidiary and designed to increase anti-tumor response in conjunction with cancer therapies by addressing resistance to these agents. - ENV 105 is an antibody that targets CD105 / Endoglin which is expressed in tumor cells and surrounding cells as the tumor becomes resistant to therapeutics in prostate cancer and lung cancer. This therapy is being tested in a randomized multicenter Phase 2 trial for prostate cancer and a Phase 1 trial in lung cancer, both of which began enrolling patients in September 2023. ENV 105 has received an IND from the FDA. - ENV 205 is an antibody that targets mitochondrial DNA which is elevated as patients become resistant to chemotherapies. This therapy is in preclinical testing. As of the date of this prospectus, our product candidates have not been approved as safe or effective by the FDA or any other comparable foreign regulator. Kairos Pharma, Ltd. was originally incorporated on June 17, 2013 under the laws of the State of California as NanoGB13, Inc. We changed our name to “Kairos Pharma, Ltd.” on July 15, 2016. On May 10, 2023, we filed a certificate of conversion with the Secretary of State of the State of California and, on the same date, we also filed with the Secretary of State of the State of Delaware a certificate of conversion from a non-Delaware corporation to a Delaware corporation pursuant to the Delaware General Corporation Law. In addition, on May 10, 2023, we also filed a certificate of incorporation with the Secretary of State of the State of Delaware and became a Delaware corporation. Our registered corporate address is 2355 Westwood Blvd., #139, Los Angeles, California.

AI Analysis | Feedback

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AI Analysis | Feedback

Kairos Pharma (symbol: KAPA) is a fictional company often used in case studies or educational materials and therefore does not have actual major products or services.

AI Analysis | Feedback

As a public pharmaceutical company, Kairos Pharma (KAPA) would primarily sell its products to other companies rather than directly to individual consumers. The major customers for a pharmaceutical manufacturer are typically the large pharmaceutical wholesale distributors, which then supply drugs to pharmacies, hospitals, and other healthcare providers.

Based on the standard business model for a pharmaceutical company operating in major markets, Kairos Pharma's major customers would include:

  • McKesson Corporation (MCK)
  • AmerisourceBergen Corporation (ABC)
  • Cardinal Health, Inc. (CAH)

These three companies are the largest pharmaceutical distributors in the United States and typically account for a significant portion of a pharmaceutical manufacturer's sales revenue, acting as the crucial intermediary in the drug supply chain.

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John S. Yu, Chief Executive Officer & Chairman
Dr. John S. Yu founded Kairos Pharma on June 17, 2013. He is an accomplished neurosurgeon and immunotherapy expert, holding a BAS from Stanford, and an MD from Harvard Medical School and MIT. Dr. Yu also serves as a Professor of Neurosurgery and Director of Surgical Neuro-Oncology at Cedars-Sinai Medical Center. He has developed numerous investigational drugs with the FDA (8 new drugs mentioned) and led multiple clinical trials. Prior to Kairos Pharma, he was the CEO and Chairman of AcTcell, and a Director of Enviro Therapeutics. His career has focused on groundbreaking research in cancer therapeutics, and he holds numerous patents for immunotherapies and nanotechnologies from his NIH-funded laboratory.

Doug Samuelson, Chief Financial Officer
Doug Samuelson brings over 25 years of experience in finance, having served as CFO for various biopharma companies. He is a CPA in the State of California. His previous roles include CFO of Wellness Center USA, CFO of AdvaVet, Inc., CFO of Solis Tek, Inc., and Director of Accounting of Second Sight Medical Products, Inc. His expertise encompasses financial management and regulatory compliance.

Neil Bhowmick, Chief Scientific Officer & President, Enviro Therapeutics
Dr. Neil Bhowmick possesses over 20 years of extensive biochemistry expertise. He has filed and prosecuted patents for therapeutics and devices, authored 110 peer-reviewed publications, and led foundational and preclinical cancer research. He holds 6 patents for biomarker detection platforms and stromal targeted therapeutics, including ENV105 and ENV205. Dr. Bhowmick's background includes a fellowship at Vanderbilt University Medical Center and serving as Research Director at Oppenheimer Urologic Reference Laboratory (OURLab). He has also been a consultant at Xencor Inc. and Tracon Pharma.

Ramchandran Murali, VP, Research and Development
Dr. Ramchandran Murali is an immunologist and molecular engineer recognized for his work in developing pharmacological agents to counter immune suppression in cancer. His extensive research background is instrumental in advancing Kairos Pharma's innovative drug pipeline. He is also a Professor of Biomedical Sciences and Research in Immunology at Penn/Cedars-Sinai Medical Center, and a leading expert in X-ray crystallography, biophysical, biochemical, and immunology fields, having made significant advances in molecular engineering and cell surface receptors. He has developed numerous technologies that reverse key mechanisms of immune suppression of cancer.

AI Analysis | Feedback

Here are the key risks to Kairos Pharma's business:
  1. Clinical Trial and Drug Development Risk: As a clinical-stage biopharmaceutical company, Kairos Pharma's success is heavily reliant on the successful outcome of its ongoing clinical trials for its lead candidate, ENV-105. ENV-105 is currently in Phase 2 clinical trials for prostate cancer and Phase 1 trials for lung cancer. There is no guarantee that the data from these trials will be positive or that the drug will effectively overcome drug resistance as intended. Failure to achieve positive results in these trials, or any future trials, could significantly impact the company's viability and future prospects.
  2. Financial Position and Need for Future Funding: Kairos Pharma is currently unprofitable, with losses increasing over the past five years. Developing new pharmaceutical products through clinical trials is a capital-intensive process. While the company has a cash balance, it may need to raise additional funds to continue its research and development efforts, especially if clinical trials are extended or further studies become necessary. The ability to secure sufficient future funding is critical and is often contingent on positive clinical trial results and favorable market conditions.
  3. Regulatory Approval Risk: Even if clinical trials for ENV-105 yield positive results, Kairos Pharma faces significant regulatory hurdles. The company must obtain extensive regulatory approvals from bodies such as the U.S. Food and Drug Administration (FDA) before it can commercialize its drug candidates. The regulatory approval process is complex, lengthy, and subject to unpredictable changes, and there is no assurance that ENV-105 will ultimately receive the necessary approvals.

AI Analysis | Feedback

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AI Analysis | Feedback

Kairos Pharma (KAPA) is a clinical-stage biopharmaceutical company focusing on oncology therapeutics. The addressable markets for their main product candidates are as follows:

  • ENV105 (Castrate-Resistant Prostate Cancer): The global castrate-resistant prostate cancer (CRPC) market was estimated at approximately USD 12.95 billion in 2024 and is projected to reach about USD 21.44 billion by 2030, growing at a Compound Annual Growth Rate (CAGR) of 8.7% from 2025 to 2030. The metastatic CRPC therapeutics market specifically was valued at USD 16.46 billion in 2024 and is projected to grow to USD 87.19 billion by 2032 with a CAGR of 22.5% during the forecast period.
  • ENV105 (Lung Cancer): The global lung cancer therapeutics market size was approximately USD 35.37 billion in 2025 and is forecasted to reach around USD 71.30 billion by 2034, exhibiting a CAGR of 8.10% from 2025 to 2034. Another estimate places the global lung cancer market at USD 38.4 billion in 2025, growing to USD 95.1 billion in 2034 with a CAGR of 10.6%.
  • KROS201 (Glioblastoma): The global glioblastoma treatment market was valued at USD 3.05 billion in 2024 and is expected to reach USD 6.22 billion by 2032, at a CAGR of 9.30% during the forecast period. Other projections estimate the global glioblastoma multiforme treatment market to grow from USD 3.72 billion in 2024 to USD 7.87 billion by 2033 with a CAGR of 8.68%.
  • KROS401 (Triple Negative Breast Cancer): The global triple negative breast cancer (TNBC) market was valued at USD 1.06 billion in 2024 and is expected to reach USD 1.63 billion by 2032, growing at a CAGR of 5.50% from 2025 to 2032. Another report indicates the global TNBC market size to be USD 1.15 billion in 2025, projected to reach USD 1.41 billion by 2029 with a CAGR of 5.1%.
  • KROS101, KROS102, KROS301: Specific addressable market sizes for these individual product candidates beyond the general oncology or immunotherapy market are not available. However, the broader global cancer immunotherapy market was valued at USD 226.38 billion in 2024 and is projected to reach USD 443.17 billion by 2030, growing at a CAGR of 11.90%. The global immunotherapy drugs market, which encompasses these types of therapies, was estimated at USD 257.6 billion in 2024 and is projected to reach USD 486.36 billion by 2030, growing at a CAGR of 11.2%.

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Expected Drivers of Future Revenue Growth for Kairos Pharma (KAPA)

Over the next 2-3 years, Kairos Pharma's potential for revenue growth is primarily linked to the successful advancement and commercialization of its clinical-stage pipeline. The key expected drivers include:

  1. Advancement and Commercialization of ENV105: Kairos Pharma's lead therapeutic candidate, ENV105, an antibody targeting CD105, is currently undergoing Phase 2 clinical trials for advanced metastatic prostate cancer and Phase 1 trials for lung cancer. The company has reported positive interim safety and efficacy results from the Phase 2 prostate cancer trial. Successful progression through clinical development, regulatory approval, and subsequent market launch of ENV105 would be a significant driver of future product revenue.
  2. Development and Launch of KROS101: The company has presented promising new data on KROS101, an investigational small molecule GITR ligand agonist, as a potential cancer immunotherapy. If KROS101 successfully navigates clinical trials and gains regulatory approval, its commercialization would introduce a new product and revenue stream for Kairos Pharma.
  3. Expansion into New Cancer Indications: Kairos Pharma's strategy involves leveraging its lead candidate, ENV105, to address multiple cancer types by reversing drug resistance and restoring the effectiveness of standard therapies. Successful clinical trials and subsequent approvals for additional cancer indications beyond prostate and lung cancer would expand the addressable market and contribute to revenue growth.
  4. Strategic Partnerships and Collaborations: Recent partnerships are anticipated to enhance Kairos Pharma's innovation in pharmaceutical products and bolster its research and development capabilities. These collaborations could generate revenue through various mechanisms, such as upfront payments, milestone payments tied to development progress, and royalty streams from licensed assets.

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Share Issuance

  • On September 16, 2024, Kairos Pharma completed its Initial Public Offering (IPO), issuing 1.55 million common shares at an offering price of $4.00 per share, raising gross proceeds of $6.2 million.
  • In January 2025, the company raised an additional $3.5 million through a Private Investment in Public Equity (PIPE) transaction by selling 2.5 million common units at $1.40 each, along with warrants.
  • The total number of shares outstanding for Kairos Pharma increased by 35.56% in one year.

Inbound Investments

  • The company's Phase 2 clinical trial for ENV105 in prostate cancer is partially funded by a $3.2 million NIH grant.
  • Kairos Pharma raised $3.5 million in January 2025 via a Private Investment in Public Equity (PIPE) transaction from accredited investors.
  • In November 2025, Kairos Pharma received a Department of Defense grant to support the study of its lead candidate ENV105 for preventing drug resistance in lung cancer, and another grant for research of ENV205 to treat chemotherapy drug resistance and cachexia.

Capital Expenditures

  • Proceeds from the IPO and subsequent financings are primarily allocated to advancing clinical trials, including Phase 1 and 2 trials for its lead candidate ENV-105 in lung and prostate cancer.
  • The company's operational expenses, largely driven by research and development as a clinical-stage biopharmaceutical company, are projected to be $3.7 million for 2025 and $7.2 million for 2026.
  • Kairos Pharma reported a quarterly burn rate of approximately $0.6 million.

Latest Trefis Analyses

Title
0ARTICLES

Trade Ideas

Select ideas related to KAPA. For more, see Trefis Trade Ideas.

Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
CRL_11142025_Dip_Buyer_FCFYield11142025CRLCharles River Laboratories InternationalDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
20.9%20.9%-3.7%
GDRX_11142025_Dip_Buyer_High_CFO_Margins_ExInd_DE11142025GDRXGoodRxDip BuyDB | CFO/Rev | Low D/EDip Buy with High Cash Flow Margins
Buying dips for companies with significant cash flows from operations and reasonable debt / market cap
-7.4%-7.4%-11.8%
ASTH_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025ASTHAstrana HealthDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
13.5%13.5%-5.5%
SGRY_11142025_Dip_Buyer_High_FCF_Yield_ExInd_DE_RevG11142025SGRYSurgery PartnersDip BuyDB | FCF Yield | Low D/EDip Buy with High Free Cash Flow Yield
Buying dips for companies with significant free cash flow yield (FCF / Market Cap) and reasonable debt / market cap
1.6%1.6%-1.4%
TFX_11072025_Dip_Buyer_FCFYield11072025TFXTeleflexDip BuyDB | FCFY OPMDip Buy with High FCF Yield and High Margin
Buying dips for companies with high FCF yield and meaningfully high operating margin
11.8%11.8%-5.1%

Recent Active Movers

More From Trefis

Peer Comparisons for Kairos Pharma

Peers to compare with:

Financials

KAPAEXELRCUSREGNAMGNBMYMedian
NameKairos P.Exelixis Arcus Bi.Regenero.Amgen Bristol-. 
Mkt Price0.7546.6122.71785.17331.4954.2850.45
Mkt Cap0.012.52.481.3178.3110.546.9
Rev LTM02,28824014,24835,97148,0348,268
Op Inc LTM-6820-3753,8078,67111,4202,314
FCF LTM-4744-4643,88111,53915,3022,313
FCF 3Y Avg-2428-3133,8539,06713,5982,140
CFO LTM-4791-4625,07113,12616,6212,931
CFO 3Y Avg-2553-3034,84810,32214,8462,700

Growth & Margins

KAPAEXELRCUSREGNAMGNBMYMedian
NameKairos P.Exelixis Arcus Bi.Regenero.Amgen Bristol-. 
Rev Chg LTM-9.9%-8.7%2.9%10.6%1.3%2.9%
Rev Chg 3Y Avg-11.8%12.7%1.4%11.2%1.0%11.2%
Rev Chg Q-10.8%-45.8%0.9%12.4%2.8%2.8%
QoQ Delta Rev Chg LTM-2.6%-8.4%0.2%3.0%0.7%0.7%
Op Mgn LTM-35.8%-156.2%26.7%24.1%23.8%24.1%
Op Mgn 3Y Avg-22.5%-179.6%30.0%25.4%19.0%22.5%
QoQ Delta Op Mgn LTM-2.1%-27.2%-0.9%0.6%2.9%0.6%
CFO/Rev LTM-34.6%-192.5%35.6%36.5%34.6%34.6%
CFO/Rev 3Y Avg-26.5%-164.2%35.4%32.7%31.7%31.7%
FCF/Rev LTM-32.5%-193.3%27.2%32.1%31.9%31.9%
FCF/Rev 3Y Avg-19.8%-171.1%28.2%28.8%29.0%28.2%

Valuation

KAPAEXELRCUSREGNAMGNBMYMedian
NameKairos P.Exelixis Arcus Bi.Regenero.Amgen Bristol-. 
Mkt Cap0.012.52.481.3178.3110.546.9
P/S-5.510.15.75.02.35.5
P/EBIT-3.015.3-7.315.716.111.113.2
P/E-3.018.5-7.117.825.518.318.0
P/CFO-3.615.8-5.216.013.66.610.1
Total Yield-33.4%5.4%-14.1%6.0%6.8%10.0%5.7%
Dividend Yield0.0%0.0%0.0%0.3%2.8%4.5%0.2%
FCF Yield 3Y Avg-4.7%-22.3%4.9%5.9%13.2%4.9%
D/E0.00.00.00.00.30.50.0
Net D/E-0.4-0.1-0.3-0.10.30.3-0.1

Returns

KAPAEXELRCUSREGNAMGNBMYMedian
NameKairos P.Exelixis Arcus Bi.Regenero.Amgen Bristol-. 
1M Rtn11.8%9.6%3.0%3.9%-1.8%17.4%6.8%
3M Rtn-34.6%17.1%83.3%38.4%16.4%22.5%19.8%
6M Rtn15.9%1.9%159.5%50.8%21.3%18.5%19.9%
12M Rtn-56.2%39.2%42.3%10.4%29.7%-1.0%20.0%
3Y Rtn-194.4%11.3%8.6%38.2%-15.0%11.3%
1M Excs Rtn7.2%5.0%-1.7%-0.8%-6.4%12.7%2.1%
3M Excs Rtn-41.4%15.7%77.4%32.2%15.5%20.5%18.1%
6M Excs Rtn5.8%-6.3%150.0%37.9%6.6%6.0%6.3%
12M Excs Rtn-73.3%20.6%29.1%-6.3%13.3%-16.6%3.5%
3Y Excs Rtn-113.0%-105.8%-70.2%-42.9%-95.0%-70.2%

Financials

Segment Financials

Revenue by Segment
$ Mil202420232022
Single Segment000
Total000


Assets by Segment
$ Mil202420232022
Single Segment110
Total110


Price Behavior

Price Behavior
Market Price$0.75 
Market Cap ($ Bil)0.0 
First Trading Date09/16/2024 
Distance from 52W High-64.7% 
   50 Days200 Days
DMA Price$0.91$1.32
DMA Trenddowndown
Distance from DMA-17.1%-43.2%
 3M1YR
Volatility91.1%179.0%
Downside Capture369.6734.33
Upside Capture106.01-52.25
Correlation (SPY)54.2%5.5%
KAPA Betas & Captures as of 11/30/2025

 1M2M3M6M1Y3Y
Beta4.783.993.081.480.401.12
Up Beta7.566.456.193.370.13-0.68
Down Beta7.096.276.565.721.44-0.89
Up Capture104%90%-68%-7%-24%-3%
Bmk +ve Days13263974142427
Stock +ve Days7172857103123
Down Capture464%311%179%-180%13%46%
Bmk -ve Days7162452107323
Stock -ve Days13233264139170

[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
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Based On 5-Year Data
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Based On 10-Year Data
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Short Interest

Short Interest: As Of Date11282025
Short Interest: Shares Quantity124,743
Short Interest: % Change Since 11152025-0.6%
Average Daily Volume134,986
Days-to-Cover Short Interest1
Basic Shares Quantity20,206,033
Short % of Basic Shares0.6%

SEC Filings

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Report DateFiling DateFiling
93020251114202510-Q 9/30/2025
6302025812202510-Q 6/30/2025
3312025514202510-Q 3/31/2025
12312024415202510-K 12/31/2024
93020241114202410-Q 9/30/2024
33120245132024S-1/A 3/31/2024
123120239172024424B4 12/31/2023
63020239292023S-1 6/30/2023
33120239182023DRS/A 3/31/2023
123120222142024S-1/A 12/31/2022
123120213292023DRS 12/31/2021