Tearsheet

Investment Highlights

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Market Valuation

 9/4/252024202320222021
Share Price CYE$720.99$615.00$380.43$378.83$350.19
Market Cap CYE ($ Bil)44.037.222.521.018.0
Total Debt ($ Bil)0.00.00.00.00.0
Total Cash ($ Bil)0.03.43.22.22.3
Enterprise Value ($ Bil)0.037.222.521.018.0
Valuation Ratios     
P/S TTM17.016.817.750.236.0
P/EBIT TTM120.5420.0-71.6-28.3-44.9
P/E TTM41.344.2-73.7-29.0-43.8
Sector Ratios     
P/S TTM (Sector)3.84.14.54.56.7
P/EBIT TTM (Sector)4.30.4-1.9-1.2-0.4
P/E TTM (Sector)-1.8-2.2-3.4-2.2-2.3
 9/4/2520242023
Share Price CYE$720.99$615.00$380.43
Market Cap CYE ($ Bil)44.037.222.5
Total Debt ($ Bil)0.00.00.0
Total Cash ($ Bil)0.03.43.2
Enterprise Value ($ Bil)0.037.222.5
Valuation Ratios   
P/S TTM17.016.817.7
P/EBIT TTM120.5420.0-71.6
P/E TTM41.344.2-73.7
Sector Ratios   
P/S TTM (Sector)3.84.14.5
P/EBIT TTM (Sector)4.30.4-1.9
P/E TTM (Sector)-1.8-2.2-3.4

Business Description

argenx SE, a biotechnology company, focuses on developing various therapies for the treatment of autoimmune diseases in the United States, the Netherlands, Belgium, Japan, Switzerland, Germany and France. Its lead product candidate is efgartigimod for the treatment of patients with myasthenia gravis, immune thrombocytopenia, pemphigus vulgaris, and chronic inflammatory demyelinating polyneuropathy in Phase III clinical trials; bullous pemphigoid and idiopathic inflammatory myopathy in Phase II/III clinical trials; and ENHANZE SC in Pre-clinical study. The company is also developing immunology innovation programs, including cusatuzumab for hematological cancer, as well as high risk MDS; ARGX-119, an antibody that targets muscle-specific tyrosine kinase stage; ARGX-117 for severe autoimmune indications; ARGX-118 for airway inflammation; and ARGX-120 to treat autoimmune diseases. Show more

Price Returns Compared

Expand for Detailed View

 202020212022202320242025Total [1]
Returns
ARGX Return83%19%8%0%62%17%320%
Peers Return11%18%23%15%2%8%103%
S&P 500 Return16%27%-19%24%23%10%100%

[1] Cumulative total returns since the beginning of 2020
[2] Peers: VRTX, ABBV, AMGN, GILD, REGN.
[3] 2025 data is for the year up to 9/3/2025 (YTD)

Latest Trefis Analyses

Recent Active Movers

Recent Active Movers

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Peer Comparisons for argenx

Financials

ARGXVRTXABBVAMGNGILDREGNMedian
Nameargenx Vertex P.AbbVie Amgen Gilead S.Regenero. 
Mkt Price-401.00211.92286.92112.71577.90286.92
Mkt Cap-102.9374.7154.4140.360.7140.3
Rev LTM-11,41958,32834,91728,86214,21428,862
Op Inc LTM--19913,6958,19210,7973,8418,192
FCF LTM-3,50018,23910,6059,3693,5569,369
FCF 3Y Avg-1,98420,2738,5908,3973,2488,397
CFO LTM-3,84619,28312,0139,8684,7449,868
CFO 3Y Avg-2,32421,1549,7538,9494,5188,949

Growth & Margins

ARGXVRTXABBVAMGNGILDREGNMedian
Nameargenx Vertex P.AbbVie Amgen Gilead S.Regenero. 
Rev Chg LTM-10.5%6.1%12.9%3.8%5.4%6.1%
Rev Chg 3Y Avg-11.0%0.6%10.0%1.6%0.3%1.6%
Rev Chg Q-12.1%6.6%9.4%1.8%3.6%6.6%
QoQ Delta Rev Chg LTM-2.9%1.7%2.3%0.4%0.9%1.7%
Op Mgn LTM--1.7%23.5%23.5%37.4%27.0%23.5%
Op Mgn 3Y Avg-26.5%27.2%26.4%39.2%30.1%27.2%
QoQ Delta Op Mgn LTM-2.0%1.0%1.6%-0.0%-0.2%1.0%
CFO/Rev LTM-33.7%33.1%34.4%34.2%33.4%33.7%
CFO/Rev 3Y Avg-22.5%37.5%32.0%31.9%33.6%32.0%
FCF/Rev LTM-30.6%31.3%30.4%32.5%25.0%30.6%
FCF/Rev 3Y Avg-19.2%36.0%28.2%30.0%24.1%28.2%

Valuation

ARGXVRTXABBVAMGNGILDREGNMedian
Nameargenx Vertex P.AbbVie Amgen Gilead S.Regenero. 
Mkt Cap-102.9374.7154.4140.360.7140.3
P/S-9.06.44.44.94.34.9
P/EBIT-23.463.614.917.112.417.1
P/E-28.399.623.322.213.623.3
P/CFO-26.819.412.814.212.814.2
Total Yield-3.5%4.0%7.5%7.3%7.6%7.3%
Dividend Yield-0.0%3.0%3.2%2.8%0.3%2.8%
FCF Yield 3Y Avg-2.1%7.3%6.2%8.0%4.4%6.2%
D/E-0.00.20.40.20.00.2
Net D/E--0.00.20.30.1-0.10.1

Returns

ARGXVRTXABBVAMGNGILDREGNMedian
Nameargenx Vertex P.AbbVie Amgen Gilead S.Regenero. 
1M Rtn--13.2%8.6%-2.6%-0.4%3.6%-0.4%
3M Rtn--10.2%14.2%-0.1%3.8%18.6%3.8%
6M Rtn--17.5%3.8%-6.5%-0.4%-14.2%-6.5%
12M Rtn--19.1%11.8%-11.2%47.3%-51.0%-11.2%
3Y Rtn-42.7%74.1%30.3%97.4%-0.0%42.7%
1M Excs Rtn--16.1%5.7%-5.4%-3.3%0.7%-3.3%
3M Excs Rtn--18.1%6.2%-7.8%-3.9%9.8%-3.9%
6M Excs Rtn--26.7%-7.7%-15.8%-11.1%-25.0%-15.8%
12M Excs Rtn--32.8%-2.4%-24.7%33.4%-66.3%-24.7%
3Y Excs Rtn--15.1%17.5%-24.3%45.4%-56.7%-15.1%

Financials

Segment Financials

Revenue by Segment

$ Mil20242023202220212020
Single Segment1,2264114974178
Total1,2264114974178


Price Behavior

Short Interest

Short Interest: As Of Date8152025
Short Interest: Shares Quantity1,805,466
Short Interest: % Change Since 7312025-4.0%
Average Daily Volume433,284
Days-to-Cover Short Interest4.17
Basic Shares Quantity60,983,325
Short % of Basic Shares3.0%