Tearsheet

Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.

0

Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -11%

Strong revenue growth
Rev Chg LTMRevenue Change % Last Twelve Months (LTM) is 128%

Low stock price volatility
Vol 12M is 47%

Megatrend and thematic drivers
Megatrends include Biotechnology & Genomics, and Precision Medicine. Themes include Gene Editing & Therapy, Biopharmaceutical R&D, Show more.

Weak multi-year price returns
3Y Excs Rtn is -27%

Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -27 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -192%

Weak revenue growth
Rev Chg QQuarterly Revenue Change % is -33%

Significant share based compensation
SBC/Rev LTMShare Based Compensation / Revenue (Sales), Last Twelve Months (LTM) is 49%

Not cash flow generative
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -281%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -281%

Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -8.4%

Key risks
ABUS key risks include [1] the binary outcome of its high-stakes LNP patent litigation against Moderna and Pfizer/BioNTech and [2] a limited financial runway with cash projected to run out by late 2026.

0 Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -11%
1 Strong revenue growth
Rev Chg LTMRevenue Change % Last Twelve Months (LTM) is 128%
2 Low stock price volatility
Vol 12M is 47%
3 Megatrend and thematic drivers
Megatrends include Biotechnology & Genomics, and Precision Medicine. Themes include Gene Editing & Therapy, Biopharmaceutical R&D, Show more.
4 Weak multi-year price returns
3Y Excs Rtn is -27%
5 Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -27 Mil, Op Mgn LTMOperating Margin = Operating Income / Revenue Reflects profitability before taxes and before impact of capital structure (interest payments). is -192%
6 Weak revenue growth
Rev Chg QQuarterly Revenue Change % is -33%
7 Significant share based compensation
SBC/Rev LTMShare Based Compensation / Revenue (Sales), Last Twelve Months (LTM) is 49%
8 Not cash flow generative
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is -281%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is -281%
9 Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -8.4%
10 Key risks
ABUS key risks include [1] the binary outcome of its high-stakes LNP patent litigation against Moderna and Pfizer/BioNTech and [2] a limited financial runway with cash projected to run out by late 2026.

Valuation, Metrics & Events

Price Chart

Why The Stock Moved

Qualitative Assessment

AI Analysis | Feedback

Arbutus Biopharma (ABUS) stock has lost about 15% since 12/31/2025 because of the following key factors:

1. European Patent Revocation Significantly Impacted Investor Confidence.

Arbutus Biopharma experienced a substantial stock decline in January 2026, primarily due to the revocation of a crucial patent in Europe. The stock plummeted by 12% on January 16, 2026, closing at $4.04, and was trending down by over 14% on January 17, 2026. This legal setback was seen as a fundamental alteration to ABUS's market position and competitive edge, particularly amidst ongoing challenges from competitors.

2. Uncertainty Surrounding the Moderna Settlement's Contingent Payment.

While Arbutus announced a $2.25 billion global settlement with Moderna in March 2026 for LNP patent infringement, a significant portion of this settlement, $1.3 billion, remains contingent upon a favorable appellate ruling. On April 7, 2026, Jefferies analyst lowered their price target for ABUS from $7 to $5.50, citing a revised view that the probability of Moderna winning the '1498 appeal (which impacts the contingent payment) increased from 25% to 75%. This uncertainty around the full settlement value contributed to downward pressure on the stock.

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Stock Movement Drivers

Fundamental Drivers

The -13.7% change in ABUS stock from 12/31/2025 to 4/12/2026 was primarily driven by a -10.2% change in the company's P/S Multiple.
(LTM values as of)123120254122026Change
Stock Price ($)4.814.15-13.7%
Change Contribution By: 
Total Revenues ($ Mil)1514-3.6%
P/S Multiple63.256.7-10.2%
Shares Outstanding (Mil)192192-0.3%
Cumulative Contribution-13.7%

LTM = Last Twelve Months as of date shown

Market Drivers

12/31/2025 to 4/12/2026
ReturnCorrelation
ABUS-13.7% 
Market (SPY)-5.4%41.2%
Sector (XLV)-4.8%34.0%

Fundamental Drivers

The -8.6% change in ABUS stock from 9/30/2025 to 4/12/2026 was primarily driven by a -8.6% change in the company's Total Revenues ($ Mil).
(LTM values as of)93020254122026Change
Stock Price ($)4.544.15-8.6%
Change Contribution By: 
Total Revenues ($ Mil)1514-8.6%
P/S Multiple56.456.70.5%
Shares Outstanding (Mil)192192-0.4%
Cumulative Contribution-8.6%

LTM = Last Twelve Months as of date shown

Market Drivers

9/30/2025 to 4/12/2026
ReturnCorrelation
ABUS-8.6% 
Market (SPY)-2.9%36.4%
Sector (XLV)6.3%34.9%

Fundamental Drivers

The 18.9% change in ABUS stock from 3/31/2025 to 4/12/2026 was primarily driven by a 128.2% change in the company's Total Revenues ($ Mil).
(LTM values as of)33120254122026Change
Stock Price ($)3.494.1518.9%
Change Contribution By: 
Total Revenues ($ Mil)614128.2%
P/S Multiple107.356.7-47.2%
Shares Outstanding (Mil)190192-1.4%
Cumulative Contribution18.9%

LTM = Last Twelve Months as of date shown

Market Drivers

3/31/2025 to 4/12/2026
ReturnCorrelation
ABUS18.9% 
Market (SPY)16.3%40.3%
Sector (XLV)2.3%42.3%

Fundamental Drivers

The 37.0% change in ABUS stock from 3/31/2023 to 4/12/2026 was primarily driven by a 369.1% change in the company's P/S Multiple.
(LTM values as of)33120234122026Change
Stock Price ($)3.034.1537.0%
Change Contribution By: 
Total Revenues ($ Mil)3914-63.9%
P/S Multiple12.156.7369.1%
Shares Outstanding (Mil)156192-19.1%
Cumulative Contribution37.0%

LTM = Last Twelve Months as of date shown

Market Drivers

3/31/2023 to 4/12/2026
ReturnCorrelation
ABUS37.0% 
Market (SPY)63.3%31.3%
Sector (XLV)19.1%33.0%

Return vs. Risk

Price Returns Compared

 202120222023202420252026Total [1]
Returns
ABUS Return10%-40%7%31%47%-11%21%
Peers Return34%-12%-19%-27%74%30%56%
S&P 500 Return27%-19%24%23%16%-0%82%

Monthly Win Rates [3]
ABUS Win Rate50%42%33%42%75%25% 
Peers Win Rate48%45%40%42%60%65% 
S&P 500 Win Rate75%42%67%75%67%50% 

Max Drawdowns [4]
ABUS Max Drawdown-30%-52%-27%-10%-12%-24% 
Peers Max Drawdown-16%-38%-40%-38%-33%-7% 
S&P 500 Max Drawdown-1%-25%-1%-2%-15%-7% 


[1] Cumulative total returns since the beginning of 2021
[2] Peers: GILD, IONS, ARWR, VIR, MRNA.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 4/10/2026 (YTD)

How Low Can It Go

Unique KeyEventABUSS&P 500
2022 Inflation Shock2022 Inflation Shock  
2022 Inflation Shock% Loss% Loss-65.1%-25.4%
2022 Inflation Shock% Gain to Breakeven% Gain to Breakeven186.4%34.1%
2022 Inflation ShockTime to BreakevenTime to Breakeven689 days464 days
2020 Covid Pandemic2020 Covid Pandemic  
2020 Covid Pandemic% Loss% Loss-73.3%-33.9%
2020 Covid Pandemic% Gain to Breakeven% Gain to Breakeven275.2%51.3%
2020 Covid PandemicTime to BreakevenTime to Breakeven111 days148 days
2018 Correction2018 Correction  
2018 Correction% Loss% Loss-93.0%-19.8%
2018 Correction% Gain to Breakeven% Gain to Breakeven1319.5%24.7%
2018 CorrectionTime to BreakevenTime to BreakevenNot Fully Recovered days120 days

Compare to GILD, IONS, ARWR, VIR, MRNA

In The Past

Arbutus Biopharma's stock fell -65.1% during the 2022 Inflation Shock from a high on 2/8/2021. A -65.1% loss requires a 186.4% gain to breakeven.

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About Arbutus Biopharma (ABUS)

Arbutus Biopharma Corporation, a biopharmaceutical company, develops novel therapeutics for chronic Hepatitis B virus (HBV) infection, SARS-CoV-2, and other coronaviruses in the United States. Its HBV product pipeline consists of AB-729, a proprietary subcutaneously delivered RNA interference product candidate, which in Phase Ia/Ib clinical trial targeted to hepatocytes that inhibits viral replication and reduces various HBV antigens using novel covalently conjugated N-acetylgalactosamine (GalNAc) delivery technology; and AB-836, an oral capsid inhibitor that suppresses HBV DNA replication. The company's research and development programs include AB-161, an oral HBV RNA destabilizer to destabilize HBV RNA, which leads in the reduction of HBsAg and other viral proteins; AB-101, an oral PD-L1 inhibitor to reawaken patients' HBV-specific immune response; and small molecule antiviral medicines to treat coronaviruses, including COVID-19. It has strategic alliance, licensing, and research collaboration agreements with Talon Therapeutics, Inc.; Gritstone Oncology, Inc.; Alnylam Pharmaceuticals, Inc.; Qilu Pharmaceuticals Co, Ltd.; Assembly Biosciences, Inc.; Acuitas Therapeutics, Inc.; and Antios Therapeutics, Inc. Arbutus Biopharma Corporation also has a clinical collaboration agreement with Vaccitech plc to evaluate a triple combination of AB-729 for the treatment of chronic HBV infection. The company was formerly known as Tekmira Pharmaceuticals Corporation and changed its name to Arbutus Biopharma Corporation in July 2015. Arbutus Biopharma Corporation is headquartered in Warminster, Pennsylvania.

AI Analysis | Feedback

Like a smaller, early-stage Gilead Sciences focused on chronic viral infections like Hepatitis B.

Alnylam Pharmaceuticals for Hepatitis B, especially given its lead RNA interference drug candidate.

AI Analysis | Feedback

  • AB-729: A subcutaneously delivered RNA interference product candidate targeting hepatocytes to inhibit viral replication and reduce HBV antigens for chronic Hepatitis B virus (HBV) infection.
  • AB-836: An oral capsid inhibitor designed to suppress HBV DNA replication for chronic HBV infection.
  • AB-161: An oral HBV RNA destabilizer program aimed at reducing HBsAg and other viral proteins for chronic HBV infection.
  • AB-101: An oral PD-L1 inhibitor program intended to reawaken patients' HBV-specific immune response for chronic HBV infection.
  • Small molecule antiviral medicines: Research and development programs for antiviral medicines to treat coronaviruses, including COVID-19.

AI Analysis | Feedback

Arbutus Biopharma (ABUS) is a biopharmaceutical company focused on developing novel therapeutics. At its current stage, the company primarily generates revenue through strategic alliances, licensing, research collaborations, and clinical collaboration agreements with other companies rather than selling approved drugs directly to individuals.

Based on the provided information, its major customers and collaborators include:

  • Gritstone Oncology, Inc. (Symbol: GRTS)
  • Alnylam Pharmaceuticals, Inc. (Symbol: ALNY)
  • Assembly Biosciences, Inc. (Symbol: ASMB)
  • Vaccitech plc (Symbol: VACC)
  • Talon Therapeutics, Inc.
  • Qilu Pharmaceuticals Co, Ltd.
  • Acuitas Therapeutics, Inc.
  • Antios Therapeutics, Inc.

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Arbutus Biopharma (ABUS) has recently updated its management team. Here are the details for key management members:

Lindsay Androski, JD, MBA, CFA

President & CEO and Chairperson
Ms. Androski joined Arbutus Biopharma in February 2025 as President and CEO and Chairperson of the Board. She is an MIT-trained biologist with nearly 30 years of experience in biotechnology, law, and academia. Prior to Arbutus, Ms. Androski served in various roles at Roivant, including President and CEO of Roivant Social Ventures and Vice President, Head of Acquisitions. At Roivant, she was responsible for the in-licensing or acquisition of more than 30 therapeutic programs, which led to the launch and incubation of 16 subsidiary biotechs and several successful IPOs. She also currently serves as Special Counsel at Genevant Sciences, focusing on LNP litigation. Ms. Androski has a background as a trial lawyer, including over a decade as an Assistant U.S. Attorney in the Eastern District of Virginia, and as a strategy consultant advising Fortune 100 clients.

Tuan Nguyen, MBA

Chief Financial Officer
Mr. Nguyen joined Arbutus Biopharma in March 2025 as Chief Financial Officer. He brings over 15 years of strategic finance experience within biopharma companies at various stages of development. Throughout his career, Mr. Nguyen has raised more than $2 billion in capital and successfully closed a partnership deal with AstraZeneca valued at $2.2 billion. Most recently, he served as CFO at Kinevant Sciences, where he oversaw finance and operational functions to support growth opportunities. His prior experience includes senior finance leadership roles at Adverum Biotechnologies, Intarcia Therapeutics, FibroGen, and UCB.

Andrew J. Sung, JD

General Counsel
Mr. Sung joined Arbutus Biopharma in April 2025 as General Counsel. He has over 20 years of legal experience, advising companies on corporate matters, intellectual property, compliance, contracting, litigation, and employment issues. An MIT-trained chemist, Mr. Sung has executed multiple life sciences transactions, including over $24 billion in M&A deals and licensing and collaboration agreements exceeding $4 billion in potential payments. Before joining Arbutus, he was General Counsel of Harmonix Music Systems, Inc. for several years and later worked at Epic Games, Inc. following Epic's acquisition of Harmonix. He also served as a Life Sciences Corporate Associate at Ropes & Gray LLP and a Senior Consultant in the Life Sciences practice at Cap Gemini Ernst & Young.

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The key risks to Arbutus Biopharma (ABUS) primarily revolve around the inherent challenges of drug development, ongoing intellectual property disputes, and intense market competition.

1. Clinical Development and Regulatory Risk

Arbutus Biopharma is a clinical-stage company with no approved products, meaning its success hinges entirely on the progression and approval of its therapeutic candidates. The company's pipeline for chronic Hepatitis B virus (HBV) infection and coronaviruses is in early to mid-stage clinical trials (e.g., AB-729 in Phase 2a leading to Phase 2b, AB-101 in Phase 1a/1b). There is a significant risk that these therapies may fail to meet clinical efficacy or safety endpoints, delaying or preventing regulatory approval. Arbutus has a history of discontinuing development for drug candidates due to safety concerns or unsatisfactory results, such as AB-506 which was terminated after acute hepatitis cases in a Phase 1a trial, and ARB-1467 and AB-452 which also faced setbacks. Furthermore, AB-101, an oral PD-L1 inhibitor, has been placed on clinical hold by the FDA, pausing its development. Achieving a "functional cure" for chronic HBV is a complex and evolving regulatory target, adding to the uncertainty of clinical success.

2. Intellectual Property and Patent Litigation Risk

Arbutus Biopharma's business model heavily relies on its patented lipid nanoparticle (LNP) delivery technology. The company has been involved in extensive, high-stakes patent infringement litigation against major pharmaceutical companies, including Moderna and Pfizer/BioNTech, concerning the use of its LNP technology in their COVID-19 mRNA vaccines. While Arbutus and Genevant Sciences recently reached a global settlement with Moderna, potentially yielding up to $2.5 billion, which includes an upfront payment of $950 million, other patent disputes are ongoing, notably with Pfizer/BioNTech. Moreover, the European Patent Office recently revoked one of Arbutus's key patents (the '254 Patent), which could impact ongoing cases in Europe. These legal battles are costly, consume substantial resources, and carry binary outcomes that can significantly affect the company's financial stability and strategic positioning.

3. Competition Risk

The markets for treatments of chronic HBV and coronaviruses are highly competitive, with numerous pharmaceutical and biotechnology companies actively developing and commercializing therapies. Arbutus faces competition in recruiting patients for its clinical programs targeting chronic HBV. Established companies with greater financial resources, larger research and development staffs, and more extensive marketing and sales capabilities could develop products that are more effective, safer, or less costly, thereby gaining a competitive advantage. This intense competition could impact Arbutus's ability to successfully develop, gain approval for, and commercialize its product candidates, even if they prove to be safe and effective.

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Addressable Markets for Arbutus Biopharma's Main Products

Arbutus Biopharma (ABUS) focuses on developing therapeutics for chronic Hepatitis B virus (HBV) infection and small molecule antiviral medicines for coronaviruses, including SARS-CoV-2 (COVID-19).

Chronic Hepatitis B (CHB) Therapeutics Market

  • The market for chronic Hepatitis B therapeutics across the seven major pharmaceutical markets (7MM), which include the U.S., France, Germany, Italy, Spain, the U.K., and Japan, was valued at approximately USD 1.6 billion in 2025. This market is projected to grow to US$3.2 billion by 2034, exhibiting a Compound Annual Growth Rate (CAGR) of 12.3% from 2025–2034.
  • Within the 7MM, the United States is the largest contributor to the CHB market, with sales of USD 710.11 million in 2024, capturing approximately 72% of the total 7MM market share in the same year.
  • Globally, the chronic hepatitis B market was valued at USD 4.6 billion in 2021 and is estimated to reach USD 6.2 billion by 2031, growing at a CAGR of 3% from 2022 to 2031. Other estimates place the global market value at USD 2,709.4 million in 2023, expected to reach USD 3,379.3 million by 2034 at a CAGR of 2.03% (2024-2034), or USD 2,764.4 million in 2024, projected to reach USD 3,482.3 million by 2035 at a CAGR of 2.13% (2025-2035).

SARS-CoV-2 and Other Coronaviruses Antiviral Medicines Market

  • The global market for specific antiviral drugs for COVID-19 experienced rapid growth, increasing from USD 15.23 billion in 2025 to USD 17.83 billion in 2026, at a CAGR of 17.1%. This market is further anticipated to grow to USD 33.17 billion by 2030, with a CAGR of 16.8%. North America was the largest regional market for specific antiviral drugs for COVID-19 in 2025.
  • The global antiviral drugs market, which includes treatments for coronavirus infection, is estimated to grow from USD 69 billion in 2025 to USD 74 billion in 2026 and reach USD 127 billion by 2035, with a CAGR of 6.1% during the 2026-2035 period. Antiviral drugs for COVID-19 treatment account for 15.7% of this overall antiviral market share.
  • The global COVID-19 therapeutics market is expected to grow at a 15.0% CAGR during the forecast period from 2026 to 2035.

AI Analysis | Feedback

Arbutus Biopharma Corporation (NASDAQ: ABUS) is a clinical-stage biopharmaceutical company primarily focused on developing novel therapeutics for chronic Hepatitis B virus (HBV) infection. Over the next 2-3 years, the company's expected revenue growth will largely be driven by the advancement of its key pipeline assets and the realization of milestone payments from strategic partnerships.

Here are 3-5 expected drivers of future revenue growth:

  1. Progression and Potential Commercialization of Imdusiran (AB-729): Arbutus Biopharma's lead RNA interference (RNAi) therapeutic, imdusiran (AB-729), is a primary expected driver of future revenue. The company has reported positive Phase 2a results, demonstrating encouraging durability and a meaningful functional cure rate in a proportion of patients with chronic HBV. Arbutus plans to initiate a placebo-controlled Phase 2b trial for imdusiran in the first half of 2025, which, if successful, could significantly advance the drug towards eventual commercialization and generate substantial revenue.
  2. Milestone Payments from the Qilu Pharmaceutical Partnership for AB-729: Arbutus has an exclusive licensing agreement and strategic partnership with Qilu Pharmaceutical for the development and commercialization of AB-729 in mainland China, Hong Kong, Macau, and Taiwan. This agreement includes potential payments of up to $245 million upon reaching certain development, regulatory, and sales milestones. As AB-729 progresses through its clinical development and regulatory pathways in these territories, Arbutus stands to receive these non-dilutive milestone payments.
  3. Advancement of AB-101 (Oral PD-L1 Inhibitor) and AB-836 (Oral Capsid Inhibitor): Arbutus is also developing AB-101, an oral PD-L1 inhibitor, and AB-836, an oral capsid inhibitor, both aimed at treating HBV infection. AB-101 is in Phase 1a/1b clinical trials, with preliminary data expected in the first half of 2024 (and 2025 in later updates). AB-836 has shown positive preliminary data in its ongoing Phase 1a/1b clinical trial. Successful progression of these candidates through clinical development could lead to further licensing opportunities, partnerships, or direct commercialization, thereby contributing to future revenue growth.

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Share Issuance

  • Arbutus Biopharma received $21.8 million in net proceeds from its at-the-market (ATM) offering program during Q1 2024, with an additional $22.4 million received in April 2024, totaling $44.2 million from this program.
  • The company did not anticipate utilizing its "at-the-market" program in 2025.
  • As of September 30, 2025, Arbutus Biopharma had 192.0 million common shares issued and outstanding.

Inbound Investments

  • Arbutus Biopharma recognized $10.4 million of previously deferred revenue during the nine months ended September 30, 2025, following the termination of its license agreement with Qilu Pharmaceutical Co., Ltd.
  • In March 2026, Arbutus Biopharma and Genevant Sciences announced a global settlement with Moderna, which includes a $950 million upfront payment due in July 2026 and a potential additional $1.3 billion contingent on a favorable appellate ruling.

Capital Expenditures

  • Arbutus Biopharma's capital expenditures were $86,000 for the trailing twelve months as of March 6, 2026.
  • The company recorded $12.6 million of restructuring costs year-to-date as of November 11, 2025, which included exiting its headquarters and discontinuing in-house research.

Better Bets vs. Arbutus Biopharma (ABUS)

Trade Ideas

Select ideas related to ABUS.

Unique KeyDateTickerCompanyCategoryTrade Strategy6M Fwd Rtn12M Fwd Rtn12M Max DD
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WAT_3202026_Monopoly_xInd_xCD_Getting_Cheaper03202026WATWatersMonopolyMY | Getting CheaperMonopoly-Like with P/S Decline
Large cap with monopoly-like margins or cash flow generation and getting cheaper based on P/S multiple
-0.4%-0.4%-3.3%
GILD_3202026_Quality_Momentum_RoomToRun_10%03202026GILDGilead SciencesQualityQ | Momentum | UpsideQuality Stocks with Momentum and Upside
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Recent Active Movers

Peer Comparisons

Peers to compare with:

Financials

ABUSGILDIONSARWRVIRMRNAMedian
NameArbutus .Gilead S.Ionis Ph.Arrowhea.Vir Biot.Moderna  
Mkt Price4.15139.1175.2665.509.5051.0558.28
Mkt Cap0.8172.612.29.01.320.010.6
Rev LTM1429,4419441,091671,9221,017
Op Inc LTM-2711,699-382301-480-3,074-204
FCF LTM-409,456-326322-397-2,075-183
FCF 3Y Avg-649,061-405-217-550-3,318-311
CFO LTM-4010,019-269339-392-1,873-154
CFO 3Y Avg-639,618-359-116-539-2,665-238

Growth & Margins

ABUSGILDIONSARWRVIRMRNAMedian
NameArbutus .Gilead S.Ionis Ph.Arrowhea.Vir Biot.Moderna  
Rev Chg LTM128.2%2.4%33.8%43,539.2%4.4%-39.9%19.1%
Rev Chg 3Y Avg2.9%2.6%19.2%14,468.6%-10.6%-52.3%2.8%
Rev Chg Q-33.2%4.7%-10.3%10,461.3%465.3%-29.3%-2.8%
QoQ Delta Rev Chg LTM-3.6%1.2%-2.4%31.5%373.9%-12.7%-0.6%
Op Mgn LTM-192.1%39.7%-40.5%27.6%-720.9%-159.9%-100.2%
Op Mgn 3Y Avg-585.4%36.4%-50.9%-8,391.7%-1,095.3%-115.3%-350.4%
QoQ Delta Op Mgn LTM22.6%1.1%-11.7%15.7%3,216.2%-2.7%8.4%
CFO/Rev LTM-281.5%34.0%-28.5%31.1%-589.0%-97.5%-63.0%
CFO/Rev 3Y Avg-602.0%33.7%-46.2%-6,576.1%-1,087.2%-79.2%-340.6%
FCF/Rev LTM-281.5%32.1%-34.5%29.5%-596.2%-108.0%-71.2%
FCF/Rev 3Y Avg-604.9%31.8%-51.9%-7,685.5%-1,111.6%-97.1%-351.0%

Valuation

ABUSGILDIONSARWRVIRMRNAMedian
NameArbutus .Gilead S.Ionis Ph.Arrowhea.Vir Biot.Moderna  
Mkt Cap0.8172.612.29.01.320.010.6
P/S56.75.913.08.219.910.411.7
P/EBIT-23.916.0-41.326.0-2.8-7.3-5.0
P/E-23.820.3-32.044.4-3.0-7.1-5.1
P/CFO-20.117.2-45.526.5-3.4-10.7-7.0
Total Yield-4.2%7.3%-3.1%2.3%-33.1%-14.1%-3.7%
Dividend Yield0.0%2.3%0.0%0.0%0.0%0.0%0.0%
FCF Yield 3Y Avg-11.8%7.5%-5.7%-11.0%-50.5%-17.7%-11.4%
D/E0.00.10.20.00.10.10.1
Net D/E-0.10.1-0.1-0.1-0.3-0.2-0.1

Returns

ABUSGILDIONSARWRVIRMRNAMedian
NameArbutus .Gilead S.Ionis Ph.Arrowhea.Vir Biot.Moderna  
1M Rtn-2.6%-4.1%5.7%19.0%2.6%-2.9%0.0%
3M Rtn-10.2%15.5%-6.3%1.5%62.4%48.8%8.5%
6M Rtn1.0%20.2%7.6%85.0%63.8%90.3%42.0%
12M Rtn32.2%37.8%169.7%455.6%71.8%94.8%83.3%
3Y Rtn40.7%84.9%100.4%114.8%-61.6%-68.2%62.8%
1M Excs Rtn-12.7%-5.3%0.0%12.1%-3.9%-9.4%-4.6%
3M Excs Rtn-9.2%17.4%-6.2%2.3%61.2%52.3%9.9%
6M Excs Rtn-1.7%18.2%6.6%76.4%56.1%81.9%37.1%
12M Excs Rtn7.3%1.6%158.2%518.6%46.2%70.3%58.3%
3Y Excs Rtn-27.4%21.2%46.6%93.7%-125.5%-133.7%-3.1%

Comparison Analyses

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Financials

Segment Financials

Revenue by Segment
$ Mil20252024202320222021
Single segment18   6
Collaborations and licenses 3154 
Non-cash royalty revenue 863 
Total18391176


Net Income by Segment
$ Mil20252024202320222021
Single segment-73    
Total-73    


Price Behavior

Price Behavior
Market Price$4.15 
Market Cap ($ Bil)0.8 
First Trading Date08/03/2015 
Distance from 52W High-16.2% 
   50 Days200 Days
DMA Price$4.35$4.17
DMA Trendupdown
Distance from DMA-4.5%-0.4%
 3M1YR
Volatility56.4%46.3%
Downside Capture1.190.90
Upside Capture268.68162.22
Correlation (SPY)41.8%33.4%
ABUS Betas & Captures as of 3/31/2026

 1M2M3M6M1Y3Y
Beta2.792.781.741.481.030.91
Up Beta3.541.852.481.630.910.83
Down Beta2.753.040.890.890.610.57
Up Capture403%467%248%210%201%145%
Bmk +ve Days7162765139424
Stock +ve Days11223162124346
Down Capture193%177%170%149%127%104%
Bmk -ve Days12233358110323
Stock -ve Days10172960114354

[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with ABUS
ABUS46.6%47.3%0.96-
Sector ETF (XLV)12.3%16.8%0.5239.2%
Equity (SPY)31.2%17.3%1.4738.4%
Gold (GLD)60.1%27.8%1.695.6%
Commodities (DBC)29.8%16.6%1.58-5.9%
Real Estate (VNQ)21.3%15.2%1.0728.5%
Bitcoin (BTCUSD)-4.3%43.7%0.0220.4%

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Based On 5-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with ABUS
ABUS4.5%55.5%0.28-
Sector ETF (XLV)6.3%14.6%0.2525.7%
Equity (SPY)11.1%17.0%0.5028.1%
Gold (GLD)22.1%17.8%1.025.4%
Commodities (DBC)11.8%18.8%0.52-0.3%
Real Estate (VNQ)3.7%18.8%0.1024.2%
Bitcoin (BTCUSD)4.3%56.5%0.3016.3%

Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 10-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with ABUS
ABUS0.1%85.6%0.36-
Sector ETF (XLV)9.8%16.5%0.4819.7%
Equity (SPY)13.8%17.9%0.6621.3%
Gold (GLD)14.2%15.9%0.745.0%
Commodities (DBC)8.6%17.6%0.417.3%
Real Estate (VNQ)5.1%20.7%0.2214.9%
Bitcoin (BTCUSD)67.6%66.9%1.079.3%

Smart multi-asset allocation framework can stack odds in your favor. Learn How

Short Interest

Short Interest: As Of Date3312026
Short Interest: Shares Quantity16.2 Mil
Short Interest: % Change Since 3152026-1.4%
Average Daily Volume2.3 Mil
Days-to-Cover Short Interest7.0 days
Basic Shares Quantity192.4 Mil
Short % of Basic Shares8.4%

Earnings Returns History

Expand for More
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
3/23/20264.2%1.2% 
11/13/2025-5.8%-11.8%2.3%
8/6/20251.8%-0.3%17.6%
3/27/2025-2.4%4.8%-1.8%
11/6/2024-1.0%-8.1%-8.3%
8/1/20241.1%-6.9%1.6%
2/29/2024-2.8%-4.9%-10.4%
11/7/2023-1.6%-4.8%9.6%
...
SUMMARY STATS   
# Positive9711
# Negative11138
Median Positive1.8%5.0%9.6%
Median Negative-2.4%-6.9%-7.6%
Max Positive10.1%16.7%31.0%
Max Negative-13.0%-21.5%-44.2%

SEC Filings

Expand for More
Report DateFiling DateFiling
12/31/202503/23/202610-K
09/30/202511/13/202510-Q
06/30/202508/06/202510-Q
03/31/202505/14/202510-Q
12/31/202403/27/202510-K
09/30/202411/06/202410-Q
06/30/202408/08/202410-Q
03/31/202405/02/202410-Q
12/31/202303/05/202410-K
09/30/202311/07/202310-Q
06/30/202308/03/202310-Q
03/31/202305/04/202310-Q
12/31/202203/02/202310-K
09/30/202211/09/202210-Q
06/30/202208/04/202210-Q
03/31/202205/05/202210-Q

Insider Activity

Expand for More
#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Hastings, David CChief Financial OfficerDirectSell20520253.2822,18372,827524,374Form
2Sims, KarenChief Medical OfficerDirectSell20520253.2819,34863,519348,635Form
3McElhaugh, Michael JInterim President & CEODirectSell20520253.2823,79078,1034,862,133Form
4Naftzger, J. ChristopherGeneral Counsel and CCODirectSell20520253.2811,33337,206283,139Form