Between Johnson & Johnson and Merck, Which Stock Looks Set to Break Out?

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Trefis
MRK: Merck logo
MRK
Merck

Merck surged 5.6% during the past Day. You may be tempted to buy more, or may want to reduce your exposure. But there is an entirely different perspective you might be missing. Is there a better alternative? Turns out, its peer Johnson & Johnson gives you more. Johnson & Johnson (JNJ) stock offers superior revenue growth across key periods, better profitability, and relatively lower valuation vs Merck (MRK) stock, suggesting you may be better off investing in JNJ

  • JNJ’s quarterly revenue growth was 9.9%, vs. MRK’s 4.9%.
  • In addition, its Last 12 Months revenue growth came in at 7.9%, ahead of MRK’s 2.9%.
  • JNJ leads on profitability over both periods – LTM margin of 26.8% and 3-year average of 25.6%.

These differences become even clearer when you look at the financials side by side. The table highlights how MRK’s fundamentals stack up against those of JNJ on growth, margins, momentum, and valuation multiples.

Trefis: MRK Stock Insights

Valuation & Performance Overview

  MRK JNJ Preferred
     
Valuation      
P/EBIT Ratio 23.3 21.9 JNJ
     
Revenue Growth      
Last Quarter 4.9% 9.9% JNJ
Last 12 Months 2.9% 7.9% JNJ
Last 3 Year Average 4.4% 4.4% JNJ
     
Operating Margins      
Last 12 Months 19.7% 26.8% JNJ
Last 3 Year Average 19.9% 25.6% JNJ
     
Momentum      
Last 3 Year Return 17.2% 62.1% JNJ

Note: For “Last 3 Year Return” metric, preferred stock is one with higher returns unless the returns are too high (>300%) which creates risk of sell off.

Relevant Articles
  1. Merck Stock Pays Out $53 Bil – Investors Take Note
  2. Why Merck Stock Jumped 70%?
  3. Why Merck Stock Jumped 60%?
  4. Buy or Sell Merck Stock?
  5. Why Merck Stock Jumped 40%?
  6. Merck Stock Capital Return Hits $91 Bil

See detailed fundamentals on Buy or Sell JNJ Stock and Buy or Sell MRK Stock. Below we compare market return and related metrics across years.

Historical Market Performance

  2021 2022 2023 2024 2025 2026 Total [1] Avg Best
Returns
MRK Return 2% 49% 1% -6% 10% 11% 75%    
JNJ Return 11% 6% -9% -5% 47% 13% 71%    
S&P 500 Return 27% -19% 24% 23% 16% 9% 98%   <===
Monthly Win Rates [3]
MRK Win Rate 42% 67% 42% 33% 50% 60%   49%  
JNJ Win Rate 58% 58% 50% 42% 83% 60%   59%  
S&P 500 Win Rate 75% 42% 67% 75% 67% 60%   64% <===
Max Drawdowns [4]
MRK Max Drawdown -20% -11% -14% -27% -27% -11%   -18%  
JNJ Max Drawdown -12% -13% -17% -14% -13% -11%   -13%  
S&P 500 Max Drawdown -5% -25% -10% -8% -19% -9%   -13% <===

[1] Cumulative total returns since the beginning of 2021
[2] 2026 data is for the year up to 5/22/2026 (YTD)
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year

Still not sure about MRK or JNJ? Consider portfolio approach.

The Best Investors Think In Portfolios

Individual stocks can soar or tank, but one thing matters: staying invested. The right portfolio can help you stay invested, capture upside, and mitigate the downside associated with any individual stock.

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